Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3019832	s-trpaab	— (—)	48239	82288	100.00%	Distribution not available
3019832	trpaab	— (—)	3589	5059	100.00%	Distribution not available
3019832	treponemapallidum,vasta-aineet	— (—)	424	491	100.00%	Distribution not available
3019832	s-treponemapallidum,vasta-aineet	— (—)	320	327	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Factors influencing health status and contact with health services

2063

3922

2.79

312.62

1.8

1.4

—

Diabetes mellitus in pregnancy

7019

23251

2.60

307.65

1.7

—

Antenatal screening

4573

7976

4.51

307.65

1.8

1.6

—

Perineal laceration during delivery

3830

17827

2.78

307.65

1.7

—

Transplanted organ and tissue status

933

2274

5.09

307.65

2.6

1.7

—

Special screening examination for infectious and parasitic diseases

6481

18762

3.66

307.65

2.2

1.6

—

Single delivery by forceps and vacuum extractor

3258

7774

3.78

307.65

1.7

1.6

—

Persons encountering health services in circumstances related to reproduction

5368

15186

2.67

307.65

1.7

1.8

—

Complications of labour and delivery

7574

23061

2.07

307.65

1.7

—

Maternal care for known or suspected fetal abnormality and damage

3135

13158

2.93

307.65

1.9

1.6

—

Other obstetric conditions, not elsewhere classified

8362

27689

2.87

307.65

1.8

1.7

—

Maternal care for known or suspected abnormality of pelvic organs

3939

14159

2.34

307.65

1.8

1.6

—

Pregnancy, childbirth and the puerperium

4255

7382

3.77

307.65

1.8

1.6

—

Maternal care related to the fetus and amniotic cavity and possible delivery problems

6904

19052

2.59

307.65

1.8

1.6

—

Postpartum haemorrhage

4215

18589

2.48

307.65

1.8

1.7

—

Other maternal disorders predominantly related to pregnancy

8135

25960

2.31

307.65

1.8

1.6

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

8321

27605

2.89

307.65

1.8

1.7

—

Premature rupture of membranes

4267

15152

2.77

307.65

1.8

1.6

—

Gestational diabetes (for exclusion)

7509

28766

2.40

307.65

1.7

—

Pregnancy examination and test

3705

7085

5.03

307.65

1.9

1.7

—

Postpartum care and examination

3704

6778

5.95

307.65

1.9

1.7

—

Labour and delivery complicated by fetal stress [distress]

4964

18476

2.33

307.65

1.7

—

Nephropathy related operations

1017

2404

5.09

307.65

2.7

1.6

—

Single delivery by caesarean section

3618

8372

3.46

307.65

1.8

1.6

—

Maternal care for other known or suspected fetal problems

5305

16478

2.85

307.65

1.8

1.6

—

Supervision of high-risk pregnancy

3712

7208

4.22

307.65

1.9

1.6

—

Dialysis, with operation codes

1025

2466

4.95

307.65

2.7

1.6

—

Prolonged pregnancy

3146

14128

2.81

307.65

1.8

1.6

—

Delivery

5234

10606

3.15

307.65

1.8

1.6

—

Care involving dialysis

750

1484

6.37

307.65

3.0

1.6

—

Outcome of delivery

3479

6718

4.66

307.65

1.8

1.6

—

Delivery, wide proxy

5015

9190

3.67

307.65

1.8

1.6

—

Other complications of labour and delivery, not elsewhere classified

3110

15192

3.37

307.65

1.7

—

False labour

5522

17446

2.51

307.65

1.9

1.6

—

Single spontaneous delivery

4977

10532

3.00

307.65

1.8

1.6

—

Supervision of normal pregnancy

4168

7771

4.17

307.65

1.9

1.6

—

Procreative management

3143

11493

2.61

307.65

1.7

1.8

—

Extracorporeal dialysis

557

1094

6.49

283.83

3.2

1.6

—

Dental caries 2

7761

40403

1.62

278.05

1.8

1.7

—

Maternal care for known or suspected malpresentation of fetus

3253

13188

2.31

277.36

1.8

1.6

—

Neurotic, stress-related and somatoform disorders

8396

40070

1.58

274.03

1.8

1.7

—

Dental caries 2 and operation codes

7694

40602

1.61

273.26

1.8

1.7

—

Dental caries 2, only avohilmo

7708

40406

1.61

272.67

1.8

1.7

—

Chronic kidney disease

1150

3781

3.22

270.34

2.6

1.5

—

Anxiety disorders

8402

40120

1.57

269.07

1.8

1.7

—

Female infertility

5226

20001

1.88

265.89

1.7

—

Anxiety (asthma-related co-morbidities)

6863

35388

1.66

265.04

1.9

1.7

—

All anxiety disorders

7127

38178

1.63

255.84

1.9

1.7

—

Long labour

3492

17404

2.07

250.80

1.7

—

Female infertility, cervigal, vaginal, other or unspecified origin

4601

18860

1.91

247.95

1.7

—

Infections with a predominantly sexual mode of transmission

4507

27868

1.87

245.17

2.4

1.7

—

Dialysis

422

807

6.91

223.46

3.3

1.6

—

Depression

8427

40594

1.50

219.70

1.8

1.7

—

Other disorders of amniotic fluid and membranes

2284

12081

2.37

215.71

1.8

1.6

—

Anxiety disorders, excluding more controls

7296

33203

1.53

208.87

1.8

1.7

—

Human immunodeficiency virus [HIV] disease

326

547

10.12

206.69

2.9

1.7

—

Kidney transplant status

530

1313

5.19

206.13

3.3

1.7

—

Mood [affective] disorders

8708

40801

1.47

202.86

1.8

1.7

—

Mood disorders

8708

40808

1.46

200.94

1.8

1.7

—

Spontaneous abortion

5220

23297

1.67

198.05

1.9

1.6

—

Renal failure

1461

5815

2.40

193.48

2.3

1.5

—

Other abnormal products of conception

4879

21410

1.73

192.59

2.0

1.6

—

Maternal care for other conditions predominantly related to pregnancy

3112

18458

1.96

191.85

1.8

1.6

—

Postpartum hemorraghe, all women as controls

4215

27506

1.80

189.67

1.8

1.7

—

Human immunodeficiency virus [HIV] disease resulting in other conditions

294

495

10.06

185.81

2.8

1.7

—

Other dialysis

331

616

7.37

182.02

3.2

1.6

—

Medical treatment for female infertility

3335

20871

1.90

179.51

1.8

1.6

—

Primary_lymphoid and hematopoietic malignant neoplasms

1053

4168

2.70

177.68

1.5

1.6

—

Multiple myeloma and malignant plasma cell neoplasms

261

380

7.97

175.34

1.5

1.3

—

Multiple myeloma, excluding all cancers (controls excluding all cancers)

262

388

7.83

173.27

1.5

1.4

—

Multiple myeloma and malignant plasma cell neoplasms

261

386

7.85

172.85

1.5

1.3

—

Primary_lymphoid and hematopoietic malignant neoplasms

1053

4228

2.66

172.29

1.5

1.6

—

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

343

665

5.68

170.67

1.5

1.4

—

Abnormal findings on antenatal screening of mother

1933

11139

2.51

164.01

1.9

1.7

—

Dermatitis and eczema

8702

42202

1.40

160.53

1.8

1.7

—

Other sexually transmitted chlamydial diseases

1543

8367

2.74

157.60

2.9

1.7

—

Gonococcal infection

356

807

5.78

155.58

5.6

1.6

—

Obstructed labour due to malposition and malpresentation of fetus

2781

15972

1.86

155.41

1.7

1.6

—

Pregnancy with abortive outcome

7189

27251

1.47

152.60

1.9

1.6

—

Preparatory care for dialysis

327

690

5.79

152.40

2.9

1.6

—

Failed induction of labour

1228

6192

3.02

152.24

1.7

—

Persons with potential health hazards related to communicable diseases

5144

36082

1.55

146.91

2.3

1.7

—

Mood disorders, excluding more controls

7528

33571

1.42

145.18

1.8

1.7

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

8615

36713

1.38

144.14

1.8

1.7

—

Cystitis

7513

33790

1.42

143.71

1.7

—

Haemorrhage in early pregnancy

2927

17899

1.76

143.02

1.8

1.6

—

Contraceptive management

2665

11228

1.76

137.00

1.7

—

L04AD Calcineurin inhibitors

816

3334

2.79

134.88

2.5

1.7

—

Acute upper respiratory infections

8033

37830

1.38

131.62

1.8

1.7

—

Syphilis

263

534

6.43

130.42

3.7

1.6

—

Unspecified human immunodeficiency virus [HIV] disease

177

254

12.68

130.39

3.1

1.8

—

Tonsillectomy and adenotomy

7119

37301

1.42

128.13

1.8

1.7

—

Disorders resulting from impaired renal tubular function

270

572

5.75

125.27

3.3

1.6

—

Other anxiety disorders

5545

36014

1.47

123.24

1.9

1.7

—

Early syphilis

180

283

10.20

120.21

4.3

1.6

—

Examination and observation for other reasons

4792

20539

1.48

116.02

1.9

1.6

—

Coxarthrosis, primary, with hip surgery

907

3873

2.27

110.50

1.2

1.4

—

Persons encountering health services in other circumstances, wide

9065

36774

1.31

107.27

1.8

1.7

—

Other diseases of hard tissues of teeth

4545

24166

1.46

106.58

1.8

1.7

—

Recurrent or chronic depression

3916

19786

1.51

104.97

1.8

1.7

—

Donors of organs and tissues

252

639

6.90

103.62

2.0

1.7

—

Multiple myeloma

128

150

9.86

103.21

1.5

1.2

—

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS)

128

150

9.86

103.21

1.5

1.2

—

Genitourinary diseases

5548

20423

1.41

102.37

1.8

1.7

—

Postpartum hemorraghe, parous women as controls

4215

27219

1.54

101.70

1.8

1.7

—

Acute upper respiratory infections of multiple and unspecified sites

6413

36571

1.37

101.14

1.8

1.7

—

Secondary hypertension

514

1891

2.98

100.65

2.9

1.6

—

Complications predominantly related to the puerperium

3123

21637

1.59

100.12

1.8

1.7

—

Atopic dermatitis

5859

38267

1.37

93.87

1.8

1.7

—

Antepartum haemorrhage, not elsewhere classified

1161

6457

2.15

93.79

1.8

1.6

—

Bronchitis

8150

42349

1.30

90.85

1.8

1.7

—

Contact with and exposure to communicable diseases

4447

33247

1.45

90.24

2.0

1.7

—

Certain infectious and parasitic diseases

8393

33275

1.30

89.83

1.8

1.6

—

Any event in cancer register

3610

29872

0.70

87.00

1.6

1.7

—

Pre-eclampsia or poor fetal growth

3705

27092

1.49

86.06

1.8

1.7

—

Coxarthrosis, primary

1150

5351

1.90

85.66

1.2

1.5

—

Other diseases of urinary system

8014

35824

1.29

85.33

1.7

—

Glomerular diseases

945

4891

2.06

84.23

2.4

1.6

—

Exclusions for E4_PCOS_CONSORTIUM

4001

33939

0.71

83.29

1.7

—

Glomerular disorders in diseases classified elsewhere

651

2952

2.40

83.24

2.5

1.7

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

449

1701

2.79

82.58

1.4

1.5

—

Headache

5548

35690

1.35

82.01

1.7

—

Diabetes, insulin treatment (Kela reimbursement)

2834

24983

0.68

81.12

1.7

—

Diabetes mellitus

4234

33999

0.72

80.75

1.7

—

Other predominantly sexually transmitted diseases, not elsewhere classified

2220

15144

1.64

78.40

2.2

1.7

—

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

4517

29979

1.39

78.33

1.7

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

2781

24384

0.68

78.06

1.7

—

Anogenital herpesviral [herpes simplex] infection

965

5449

2.22

77.94

2.1

1.7

—

Preterm labour and delivery

1787

11408

1.67

77.66

1.7

1.6

—

Diabetes, varying definitions

4161

33343

0.73

77.47

1.7

—

Diabetes medication

4118

33553

0.73

76.56

1.7

—

Depression or dysthymia

4987

21102

1.36

76.52

1.8

1.7

—

Female infertility, associated with anovulation

1692

11342

1.88

76.23

1.7

—

Coxarthrosis [arthrosis of hip](FG)

1242

5074

1.80

75.73

1.3

1.5

—

Bacterial infection, other or unspecified

1971

11515

1.59

74.95

1.7

1.6

—

Chronic diseases of tonsils and adenoids

6864

34581

1.30

74.63

1.8

1.7

—

General examination and investigation of persons without complaint and reported diagnosis

5092

20626

1.35

74.35

1.8

1.6

—

Need for other prophylactic measures

375

1401

3.04

74.13

6.3

1.6

—

Non-follicular lymphoma, hilmo, excluding all cancers

329

1132

3.10

72.86

1.4

1.5

—

Pregnancy hypertension

4255

29284

1.39

71.50

1.7

—

Poor fetal growth

2124

14961

1.68

70.71

1.8

1.7

—

Fever of other and unknown origin

3654

25067

1.40

70.66

1.7

—

Any operation in hilmo

576

1269

2.51

70.12

1.8

1.7

—

Finngen Rheumatological endpoints

5145

37663

0.76

69.99

1.6

1.7

—

Coxarthrosis

1210

4694

1.78

69.94

1.3

1.5

—

Medical observation and evaluation for suspected diseases and conditions

5234

20629

1.34

69.87

1.8

1.6

—

Non-follicular lymphoma

329

1162

3.02

69.52

1.4

1.5

—

Gout

578

2406

2.25

68.06

1.9

1.6

—

Other disorders of kidney and ureter

488

2115

2.45

68.01

2.6

1.5

—

Asymptomatic human immunodeficiency virus [HIV] infection status

140

11.27

66.45

3.1

1.6

—

Persons encountering health services for examination and investigation

5299

20629

1.32

65.78

1.8

1.6

—

Placenta praevia

613

3147

2.40

63.86

1.7

1.6

—

Other and unspecified polyneuropathies, also in other diseases

551

2580

2.22

62.90

1.6

—

Diseases of male genital organs

2028

6796

1.54

62.25

2.0

1.8

—

Dental caries 2 and operation codes, only avohilmo

5945

29591

1.29

61.38

1.8

1.7

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

4941

31914

1.31

59.94

1.7

—

Polyhydramnios

667

3645

2.28

59.10

1.7

1.6

—

General symptoms and signs

8903

37188

1.23

58.87

1.7

—

Anaemia in chronic diseases classified elsewhere

142

330

4.98

58.34

3.6

1.6

—

Nerve, nerve root and plexus disorders

4114

33379

0.76

58.24

1.6

1.7

—

Primary coxarthrosis, bilateral

490

2269

2.21

56.70

1.3

1.4

—

Intestinal infectious diseases

6916

44266

1.25

56.57

1.8

1.7

—

Other puerperal infections

1407

9644

1.79

56.27

1.8

1.7

—

Polyneuropathies and other disorders of the peripheral nervous system

642

3332

2.00

55.38

1.6

—

Infections of genitourinary tract in pregnancy

1195

7720

1.77

55.28

1.6

—

Gout, FINNGEN

578

2885

2.05

54.98

1.9

1.5

—

Explicit Sepsis

1888

12458

1.50

54.82

1.9

1.6

—

Acute renal failure

542

2670

2.10

53.99

2.0

1.5

—

Diseases of middle ear and mastoid

5979

40191

1.27

53.39

1.8

1.7

—

Implicit bacterial Sepsis

1062

5896

1.69

53.23

1.9

1.6

—

Multiple delivery

551

2805

2.15

53.13

1.7

1.5

—

Other disorders of penis

380

1649

2.44

52.96

2.2

1.8

—

Cardiovascular diseases (excluding rheumatic etc)

5038

36050

0.78

52.78

1.7

—

Symptoms and signs involving the digestive system and abdomen

7645

31875

1.23

51.19

1.8

1.7

—

Septicaemia

1453

9231

1.55

51.13

1.9

1.6

—

Aplastic and other anaemias

1367

8441

1.57

51.00

1.8

1.6

—

Other septicaemia

1281

8101

1.59

50.67

1.9

1.6

—

Multiple gestation

936

5759

1.81

50.57

1.7

1.6

—

Abdominal and pelvic pain

7600

31875

1.22

49.52

1.8

1.7

—

Other special examinations and investigations of persons without complaint or reported diagnosis

5092

20629

1.28

49.47

1.7

1.6

—

Twin gestation

909

5587

1.81

49.37

1.7

1.6

—

Other diseases of intestines

5995

42291

0.81

49.09

1.8

1.7

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

2768

21829

0.74

49.07

1.5

1.6

—

Gestational [pregnancy-induced] hypertension

2930

22495

1.39

49.06

1.7

1.6

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

2771

21842

0.74

48.98

1.5

1.6

—

Malignant neoplasm, wide definition for exclusion

2771

21842

0.74

48.97

1.5

1.6

—

Failure and rejection of transplanted organs and tissues

128

327

5.03

48.32

2.4

1.7

—

Excessive vomiting in pregnancy

991

6338

1.78

47.69

1.8

1.6

—

Diseases of oesophagus, stomach and duodenum

4504

34129

0.79

47.50

1.7

—

Unspecified kidney failure

267

1030

2.71

47.39

2.4

1.5

—

Statin medication

2192

16889

0.71

47.05

1.7

1.6

—

Triptan medication for migraine, single purchase ok

6832

38719

1.23

46.90

1.7

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

6832

38719

1.23

46.90

1.7

—

Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)

146

6.64

46.86

1.4

1.5

—

Asthma/COPD (KELA code 203)

5055

43642

0.80

46.52

1.7

—

Personal history of other diseases and conditions

1308

8868

1.63

46.43

2.2

1.7

—

Non-Hodgkin lymphoma, all

129

331

4.18

45.46

1.4

1.5

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

4758

30532

1.28

44.84

1.7

—

Type 2 diabetes

3536

26781

0.77

44.80

1.7

1.6

—

Covid-19 confirmed case

1931

13977

1.45

44.72

1.8

1.7

—

Chronic periapical parodontitis

912

5619

1.69

44.57

1.8

1.6

—

Bacterial Sepsis

1384

8305

1.51

43.43

1.8

1.6

—

Other heart diseases, wide

4337

33318

0.79

43.34

1.7

—

Antihypertensive medication - note that there are other indications

5972

38940

0.81

42.63

1.7

—

Mantle cell lymphoma

9.41

42.40

1.4

1.3

—

L04AA Selective immunosuppressants

1135

7491

1.58

41.95

2.1

1.7

—

Parodontitis or/and operation codes

2628

20421

0.75

41.64

1.7

—

Inflammatory bowel disease treatment related agents

6427

43379

0.83

41.52

1.6

1.7

—

Fall on same level

6754

44580

0.83

40.87

1.7

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

3059

24163

1.33

40.64

1.8

1.7

—

Other (not insulin) diabetes medications

3025

23432

0.77

40.53

1.7

1.6

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

574

6600

0.56

40.48

1.3

1.5

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

574

6597

0.56

40.41

1.3

1.5

—

Medical abortion

5869

26675

1.23

40.19

1.7

1.6

—

Other anaemias

1181

7581

1.53

40.06

1.7

1.6

—

Noninflammatory disorders of female genital tract

5558

23348

1.25

39.90

1.7

—

Chronic periodontitis

481

2537

1.97

39.90

2.1

1.6

—

Any gastric operation

7957

34157

1.19

39.80

1.8

1.7

—

GASTRO-related operations

7957

34157

1.19

39.80

1.8

1.7

—

Other and unspecified anaemias

1165

7489

1.54

39.77

1.7

1.6

—

Other symptoms and signs involving cognitive functions and awareness

1367

8801

1.49

39.63

1.5

1.6

—

Gingivitis and periodontal diseases

5721

24503

1.23

39.52

1.7

1.6

—

Polycystic ovarian syndrome, broad definition

2065

15998

1.49

39.50

1.7

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

3059

24253

1.33

39.49

1.8

1.7

—

Malignant neoplasm

2512

19558

0.75

39.48

1.5

1.6

—

Inflammatory diseases of female pelvic organs

5558

35134

1.23

38.87

1.8

1.7

—

Disorders of gallbladder, biliary tract and pancreas

3146

25708

0.78

38.21

1.6

—

Psychiatric diseases

7808

33468

1.19

37.87

1.7

—

Other obstetric trauma

668

4129

1.89

37.80

1.7

1.6

—

Malignant neoplasm of breast

557

6986

0.57

37.65

1.3

1.5

—

Type 2 diabetes, definitions combined, including avohilmo

3066

23075

0.77

37.65

1.7

1.6

—

Viral Sepsis

859

5475

1.63

36.76

1.9

1.7

—

Oral corticosteroids

5219

37782

0.82

36.59

1.6

1.7

—

Implicit viral Sepsis

855

5459

1.63

36.32

1.9

1.7

—

Leiomyoma of uterus

1379

10984

0.69

35.95

1.5

1.6

—

Enlarged lymph nodes

937

6147

1.60

35.93

1.7

—

8061

36716

1.18

35.84

1.7

—

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

1979

15134

1.42

35.70

1.8

1.7

—

Leiomyoma of uterus

1500

11903

0.70

35.66

1.5

—

Biguanides

2899

22673

0.78

35.21

1.6

—

Diseases of pulp and periapical tissues

1796

13285

1.39

35.18

1.8

1.6

—

Diseases of oral cavity, salivary glands and jaws

5701

24516

1.21

35.16

1.7

1.6

—

Mycoses

1358

9627

1.46

34.84

1.8

1.7

—

Male infertility

296

1399

2.31

34.79

1.7

2.0

—

Parasetamol

7604

33449

1.18

34.75

1.8

1.7

—

Iridocyclitis

1137

7804

1.51

34.61

1.5

1.7

—

Diffuse large B-cell lymphoma, helper endpoint

138

445

3.31

34.52

1.4

1.5

—

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

138

445

3.31

34.52

1.4

1.5

—

Malignant neoplasm of breast, HER2-negative

519

6591

0.57

34.39

1.3

1.5

—

Need for immunization against other single viral diseases

143

485

3.44

34.38

2.5

1.6

—

Other and unspecified dermatitis

2731

21490

1.30

34.27

1.7

—

Any event in hilmo or specialist outpatient

120

5.04

33.99

1.9

1.3

—

Hypertensive Renal Disease

102

272

3.96

33.99

2.4

1.4

—

Pain in throat and chest

4150

30780

0.81

33.96

1.8

1.7

—

Heart failure, not strict

1882

9584

1.37

33.83

2.0

1.5

—

Other intervertebral disc disorders

3258

24824

0.79

33.75

1.6

1.7

—

Habitual aborter

392

2231

2.39

33.59

2.2

1.6

—

Provisional assignment of new diseases of uncertain etiology

3598

29427

1.26

33.55

1.8

1.7

—

Codes for special purposes

3601

29454

1.26

33.55

1.8

1.7

—

Diffuse large B-cell lymphoma

138

453

3.25

33.52

1.4

1.5

—

Diabetic nephropathy

515

2900

1.83

33.48

2.3

1.6

—

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

125

386

3.42

33.39

1.5

1.4

—

Cystic kidney disease

213

902

2.66

33.01

2.7

1.7

—

Type 2 diabetes, strict (exclude DM1)

2988

22395

0.79

32.96

1.7

1.6

—

Any mental disorder

7772

33676

1.17

32.74

1.7

—

Abnormalities of breathing

5580

38997

0.83

32.53

1.7

—

Certain disorders involving the immune mechanism

804

5197

1.61

32.36

1.7

—

Type 2 diabetes, definitions combined

2992

22361

0.79

32.32

1.7

1.6

—

Menorrhagia

1731

12766

0.73

32.18

1.6

—

Alzheimer’s disease, wide definition, excluding more controls

193

496

2.69

32.11

1.1

1.2

—

Dermatitis

3213

25950

1.26

32.06

1.7

—

Pain (limb, back, neck, head abdominally)

5757

24425

1.20

31.99

1.7

—

Persons encountering health services in other circumstances

2846

22788

1.29

31.72

1.8

1.7

—

ILD medications: immunosuppressive drugs

3700

29128

1.24

31.66

1.8

1.7

—

Cytomegalovirus infection, IBD co-morbidity

153

565

3.13

31.57

2.2

1.7

—

Disorders of sclera, cornea, iris and ciliary body

2921

23397

1.28

31.57

1.7

—

Artrosis, including avohilmo

2473

17342

0.77

31.30

1.5

1.6

—

Pre-eclampsia

1800

13728

1.39

31.17

1.7

1.6

—

Pre-eclampsia or eclampsia

1842

14079

1.38

31.14

1.7

1.6

—

Other and unspecified syphilis

10.46

31.03

3.1

1.7

—

Retained placenta and membranes, without haemorrhage

759

4933

1.63

30.98

1.8

1.6

—

Alzheimer’s disease (Late onset), excluding more controls

167

396

2.86

30.94

1.1

1.2

—

Diabetic retinopathy, strict definition

630

3402

1.69

30.72

2.0

1.7

—

Chronic nephritic syndrome

202

861

2.56

30.23

2.8

1.6

—

Polycystic ovarian syndrome, consortium definition

5102

36094

0.83

30.07

1.7

—

Other necrotizing vasculopathies

246

1133

2.29

30.02

1.6

—

Other necrotizing vasculopathies (FG)

203

862

2.49

29.92

1.5

1.6

—

Ectopic pregnancy

1187

8501

1.47

29.71

1.7

1.6

—

Cytomegaloviral disease

157

607

2.97

29.65

2.2

1.7

—

Anterior Iridocyclitis

996

6885

1.50

29.33

1.6

1.7

—

Other disorders involving the immune mechanism, not elsewhere classified

210

935

2.53

29.22

2.4

1.7

—

ILD medications: prednisolone, methylprednisolone, prednisone

6170

40391

0.85

29.14

1.7

—

Other/unspecified cytomegaloviral diseases

136

495

3.21

29.04

2.3

1.7

—

Candidiasis

848

5738

1.56

28.80

1.9

1.7

—

Hyperlipidaemia, other/unspecified

718

4355

1.58

28.69

1.7

1.5

—

Endometriosis diagnosis and infertility diagnosis occurring together

1066

7644

1.51

28.46

1.7

1.6

—

Heart failure and antihypertensive medication

626

2538

1.66

28.37

1.8

1.5

—

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

198

873

2.56

28.25

2.4

1.7

—

Other obstructed labour

563

3512

1.73

28.11

1.6

—

Cholelithiasis, broad definition with cholecystitis

2613

22363

0.79

28.06

1.6

—

Alzheimer disease, excluding more controls

210

593

2.40

27.73

1.1

1.3

—

Gout, strict definition

300

1523

2.01

27.57

2.0

1.4

—

Acute and subacute iridocyclitis

939

6498

1.50

27.54

1.6

1.7

—

Gout, unspecified

351

1880

1.91

27.49

2.0

1.4

—

Labour and delivery complicated by umbilical cord complications

442

2625

1.87

27.44

1.8

1.6

—

Gout, idiopatic and unspecified

420

2378

1.80

27.42

2.0

1.5

—

Cardiac arrhythmias

3112

25064

0.80

27.26

1.7

—

Chorioretinal inflammation

195

871

2.52

27.00

1.4

1.7

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

3915

16355

1.23

26.93

1.8

1.7

—

Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases

10.71

26.80

3.2

2.0

—

Other disorders of ear

2792

22925

0.80

26.41

1.6

—

Abnormalities of forces of labour

717

4818

1.58

25.43

1.7

1.6

—

Secondary and unspecified malignant neoplasm of lymph nodes

307

1636

1.97

25.26

1.5

1.6

—

Dementia, including avohilmo

561

2382

1.64

25.10

1.2

1.4

—

Lung transplant status

159

5.07

25.08

1.2

1.7

—

Persons encountering health services for specific procedures and health care

5719

40773

0.86

25.01

1.8

1.7

—

Codeine or tramadol medication

6574

41518

0.86

24.79

1.7

—

Unspecific neurodegenerative disorder

444

1779

1.74

24.62

1.1

1.3

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

3269

27211

1.24

24.50

1.8

1.7

—

Infections of breast associated with childbirth

533

3519

1.81

24.42

1.8

1.7

—

Dental operations

3141

13220

1.24

24.20

1.7

1.6

—

Hyperparathyroidism

372

2088

1.80

24.15

2.5

1.5

—

Glomerulonephritis

442

2664

1.74

24.14

2.3

1.6

—

Benign neoplasms

6600

41889

0.87

24.09

1.7

—

Dentinal caries

1237

9146

1.39

23.99

2.0

1.7

—

Cholelithiasis

2520

21772

0.80

23.98

1.6

—

Migraine

4925

36297

1.19

23.95

1.7

—

Lung transplantation

165

4.86

23.91

1.2

1.7

—

Dementia

519

2192

1.65

23.83

1.2

1.4

—

Diseases of the skin and subcutaneous tissue

7772

34499

1.15

23.79

1.7

—

Organic, including symptomatic, mental disorders

874

4350

1.47

23.71

1.4

1.5

—

Influenza and pneumonia

5733

43161

0.86

23.59

1.7

—

Substance abuse

3258

25989

1.22

23.55

1.8

1.7

—

Dental caries 1 and operation codes

4989

21963

1.18

23.46

1.7

—

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

280

1066

1.98

23.28

1.4

1.6

—

Diabetic nephropathy, excluding more controls

507

2640

1.66

23.21

2.3

1.7

—

Liveborn infants according to place of birth

116

417

3.43

23.19

2.0

1.7

—

Disorders of parathyroid gland

444

2647

1.69

23.12

2.4

1.5

—

Mental and behavioural disorders due to psychoactive substance use

3399

26921

1.21

23.10

1.8

1.7

—

Complications of the puerperium, not elsewhere classified

531

3523

1.75

23.00

1.6

1.7

—

994

7240

1.45

22.98

1.9

1.7

—

Acute peritonitis

231

1160

2.09

22.66

2.7

1.6

—

Assault

1121

8365

1.42

22.61

2.0

1.8

—

Other assisted single delivery

182

875

2.50

22.37

1.7

1.6

—

Dental caries

1439

10937

1.34

22.36

1.9

1.7

—

Viral infections characterized by skin and mucous membrane lesions

2338

19033

1.26

22.07

1.9

1.7

—

Substance use, excluding alcohol

1384

10638

1.35

22.02

1.9

1.8

—

Chronic periodontitis, complicated

280

1513

1.92

21.93

2.1

1.6

—

ILD medications: nintedanib

8.69

21.87

1.3

—

Inflammatory disease of uterus

1440

11255

1.36

21.70

1.8

1.7

—

Other disorders of teeth and supporting structures

899

6440

1.44

21.63

1.8

1.6

—

Other diseases of blood and blood-forming organs, wide

816

5744

1.46

21.62

1.6

1.7

—

Gout due to impairment of renal function

5.42

21.27

3.0

1.6

—

Dental caries 3 and operation codes

5481

24497

1.16

21.22

1.7

—

Mature T/NK-cell lymphomas, hilmo

143

4.41

21.17

1.4

—

Other specific joint derangements/joint disorders

5015

38473

0.86

21.11

1.7

—

Use of hypnotics and sedatives

4525

30276

0.85

20.87

1.7

—

Giant cell arteritis

332

2.99

20.69

1.2

1.4

—

Injuries to the ankle and foot

5485

44005

1.16

20.51

1.8

1.7

—

Progressive vascular leukoencephalopathy

153

4.01

20.48

1.1

1.2

—

Any dementia, excluding more controls

408

1695

1.69

20.47

1.2

1.3

—

Viral hepatitis, IBD co-morbidity

480

3116

1.66

20.47

2.0

1.7

—

Other nutritional deficiencies

4557

38744

1.17

20.46

1.7

—

Mature T/NK-cell lymphomas, hilmo, excluding all cancers

147

4.29

20.41

1.4

—

Thrombocytopenia, unspecified

295

1674

1.86

20.16

1.5

1.6

—

IgA nephropathy (IgA glomerulonephritis)

155

715

2.42

19.98

2.7

1.7

—

Use of other anti-dementia drugs

237

1076

1.94

19.62

1.1

1.2

—

Use of memantine

237

1076

1.94

19.62

1.1

1.2

—

Endometriosis

2493

17798

0.81

19.61

1.7

1.6

—

Oedema, not elsewhere classified

1109

8283

1.36

19.59

1.7

1.6

—

Delirium, not induced by alcohol and other psychoactive substances

229

1196

1.96

19.58

1.6

1.5

—

Substance abuse, excluding more controls

3258

24181

1.20

19.57

1.8

1.7

—

Mental and behavioural disorders due to alcohol

2612

21158

1.22

19.54

1.9

1.7

—

Other reaction to severe stress, and adjustment disorders

3341

28592

1.20

19.54

1.8

1.7

—

Late syphilis

211

3.67

19.47

2.9

1.6

—

Abnormal findings on diagnostic imaging of lung

922

6531

1.39

19.45

1.4

1.5

—

Other disorders of breast and lactation associated with childbirth

359

2374

2.09

19.41

1.9

1.7

—

Endocrine, nutritional and metabolic diseases

7761

35451

1.13

19.31

1.8

1.7

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

630

2970

1.51

19.31

1.9

1.5

—

Codeine

6202

38359

0.88

19.29

1.7

—

Heart failure,strict

862

4451

1.41

19.13

1.7

1.4

—

Selective serotonin reuptake inhibitors

7337

34553

1.13

19.07

1.8

1.7

—

Hypertensive heart and/or renal disease

393

1853

1.66

19.05

2.2

1.4

—

Coagulation defects, purpura and other haemorrhagic conditions

1020

7645

1.38

19.04

1.7

—

Benign neoplasms

6237

39602

0.88

19.04

1.7

—

Intrahepatic Cholestasis of Pregnancy (ICP)

833

6197

1.48

18.87

1.8

1.7

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

1808

13429

1.26

18.78

1.5

1.6

—

Idiopathic pulmonary fibrosis

138

606

2.34

18.72

1.3

1.4

—

Alzheimer’s disease, wide definition

224

972

1.95

18.71

1.1

1.2

—

Purpura and other haemorrhagic conditions

644

4483

1.49

18.67

1.7

—

Disorders of vitreous body

1007

7324

1.36

18.66

1.7

1.5

—

Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8

851

6322

1.45

18.65

1.8

1.7

—

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

299

4100

0.58

18.59

1.2

1.4

—

Disorders of vitreous body and globe

1045

7619

1.35

18.58

1.7

1.5

—

Pneumocystosis

222

3.48

18.54

1.7

—

Conjunctivitis

5621

43489

1.15

18.32

1.7

—

Pruritus

615

4275

1.51

18.24

1.8

1.7

—

Secondary uncertain malignant neoplasm

336

2020

1.71

18.18

1.4

1.6

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2569

21422

1.21

17.96

1.7

1.6

—

Hyperkalaemia

124

531

2.42

17.94

2.6

1.6

—

Missing teeth due to accident, extraction or parodontitis

368

2277

1.67

17.93

1.8

1.6

—

COPD/asthma/ILD related infections

7650

34463

1.12

17.87

1.7

—

COPD/asthma related infections

7650

34463

1.12

17.87

1.7

—

Other pulmonary diagnosis

6057

26937

1.14

17.82

1.7

—

Inflammatory disorders of breast

749

5541

1.50

17.81

1.9

1.7

—

Dental operations, only avohilmo

3260

14156

1.19

17.78

1.7

1.6

—

Hypothyroidism (congenital or acquired)

3720

18522

1.19

17.78

1.8

1.7

—

Alzheimer disease, including avohilmo

323

1372

1.71

17.46

1.1

1.2

—

Symptoms and signs involving the skin and subcutaneous tissue

3693

31806

1.17

17.45

1.8

1.7

—

Excluding asthma or asthma-COPD overlap

6049

26937

1.14

17.43

1.7

—

Postpartum haemorrhage due to anatomy

2115

18120

1.31

17.42

1.8

1.7

—

Deposits [accretions] on teeth

370

2246

1.68

17.42

2.1

1.7

—

N06DA Anticholinesterases

311

1477

1.72

17.36

1.1

1.3

—

Use of anticholinesterases

311

1477

1.72

17.36

1.1

1.3

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

117

498

2.46

17.34

1.4

1.5

—

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

233

1283

1.88

17.30

1.5

—

Sleep disorders (combined)

4156

31229

0.86

17.27

1.7

—

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

198

3.39

17.23

1.2

1.4

—

Chronic lymphocytic leukaemia, helper endpoint

198

3.39

17.23

1.2

1.4

—

Alzheimer’s disease (Late onset)

192

836

1.99

17.17

1.1

1.2

—

ILD medications: pirfenidone

6.14

17.16

1.2

1.3

—

Hernia of abdominal wall, postoperative

536

3637

1.51

17.11

1.9

1.5

—

Chronic lymphocytic leukaemia

199

3.37

17.09

1.2

1.4

—

ILD, hospital admission 2, with pulmonary infections

196

1021

1.97

17.06

1.4

1.5

—

Hypothyroidism, levothyroxine purchases

3692

18461

1.19

16.94

1.8

1.7

—

Hypothyroidism and >3 levothyroxin purchases

3692

18461

1.19

16.94

1.8

1.7

—

Other respiratory diseases principally affecting the interstitium

338

2069

1.66

16.89

1.6

1.5

—

Degenerative diseases of the nervous system

347

1587

1.66

16.80

1.1

1.3

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo

117

506

2.42

16.74

1.4

1.5

—

Excessive attrition of teeth

3005

13896

1.20

16.69

1.8

1.7

—

Any dementia

418

1878

1.58

16.46

1.2

1.4

—

Erosion of teeth, including avohilmo

1602

12576

1.28

16.42

1.8

1.7

—

Other disorders of fluid, electrolyte and acid-base balance

687

4730

1.42

16.42

1.8

1.6

—

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

149

727

2.21

16.35

1.4

1.7

—

Persons encountering health services for specific procedures, not carried out

536

3735

1.52

16.22

2.1

1.7

—

Ovarian cyst

3012

20231

0.84

16.20

1.7

—

COPD differential diagnosis

6018

26911

1.13

16.19

1.7

—

Chlamydial lymphogranuloma (venereum)

65.74

16.11

3.4

1.8

—

ILD differential diagnosis

6011

26890

1.13

16.05

1.7

—

Gender identity disorders

1553

0.34

16.02

1.8

—

Alcohol use disorder, ICD-based

1869

15384

1.24

15.83

1.8

1.7

—

ILD, hospital admissions 1, main diag only

248

1425

1.78

15.76

1.4

1.5

—

Orchitis and epididymitis

248

1430

1.78

15.70

2.1

1.8

—

Polyarthrosis

272

1533

1.72

15.64

1.4

—

Spirochaetal infections, other/unspecified

311

1920

1.69

15.62

1.5

1.6

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

501

3429

1.50

15.59

1.7

1.6

—

All pneumoniae

5123

39683

0.88

15.57

1.7

—

Shoulder lesions

2100

15468

0.82

15.53

1.5

1.6

—

Congenital malformations of the urinary system

396

2625

1.62

15.46

2.3

1.8

—

Other inflammation of vagina/vulva

434

2999

1.64

15.39

1.9

1.7

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

1989

16496

1.22

15.39

1.8

1.7

—

Rare circulating lymphoid malignancy

149

746

2.15

15.29

1.4

1.7

—

Chronic viral hepatitis

434

2957

1.58

15.17

1.9

1.8

—

Pain in joint

4110

23902

1.16

15.16

1.7

—

ILD, hospital admissions

274

1637

1.71

15.12

1.4

1.5

—

ILD medications

7068

42788

0.90

15.11

1.7

—

Problems related to lifestyle

848

6462

1.38

15.03

1.9

1.7

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

3065

23169

0.85

15.00

1.6

—

Other interstitial pulmonary diseases

275

1651

1.70

14.90

1.4

1.5

—

Interstitial lung disease

275

1651

1.70

14.90

1.4

1.5

—

Interstitial lung disease endpoints

275

1651

1.70

14.90

1.4

1.5

—

Malignant immunoproliferative diseases

4.85

14.89

1.4

1.3

—

Autoimmune diseases excluding thyroid diseases, strict definition

6250

38606

0.89

14.85

1.7

—

Protozoal diseases

127

606

2.26

14.82

1.6

1.7

—

Polyarthropathies

2959

22887

0.85

14.77

1.7

—

Disorders of conjunctiva

5843

44061

1.13

14.75

1.7

—

Placental disorders

136

709

2.50

14.73

1.8

1.6

—

Other diseases of upper respiratory tract

7483

35430

1.11

14.73

1.7

—

Pneumonias (Asthma/COPD co-morbidities)

5070

39316

0.88

14.73

1.7

—

Other diseases of anus and rectum

960

7372

1.32

14.48

1.8

1.6

—

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

657

4863

1.44

14.48

1.7

1.6

—

Dental pulpitis 3, only avohilmo

2696

17300

1.24

14.46

1.9

1.8

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

385

2532

1.56

14.41

1.4

1.6

—

Dental caries 3

4733

21445

1.14

14.24

1.7

—

Autoimmune diseases excluding thyroid diseases

6375

39099

0.90

14.24

1.7

—

Malignant immunoproliferative diseases

4.67

14.23

1.4

—

Other viral diseases

2424

20702

1.20

14.18

1.9

1.7

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2323

19692

1.19

14.11

1.7

1.6

—

Malignant neoplasm of breast, HER-positive

293

4565

0.63

14.05

1.2

1.4

—

Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, excluding all cancers (controls excluding all cancers)

5.62

14.00

1.5

1.3

—

First line medication for Crohn's disease

7079

42416

0.90

13.99

1.7

—

Pain in limb

4327

35199

0.88

13.94

1.7

—

Other viral hepatitis

481

3393

1.51

13.91

1.9

1.7

—

Complications associated with artificial fertilization

281

1845

1.86

13.86

1.8

1.7

—

Temporal arteritis

300

2.67

13.77

1.1

1.4

—

Dysphagia

691

5103

1.38

13.75

1.7

1.6

—

Presence of other functional implants

1006

5498

1.31

13.72

1.6

1.5

—

Acute alcohol intoxication

1168

9298

1.28

13.68

1.8

1.7

—

Other antidepressants

7261

34487

1.11

13.67

1.8

1.7

—

Other mental disorders due to brain damage and dysfunction and to physical disease

239

1418

1.72

13.66

1.4

1.5

—

Alcohol abuse, main dg, excluding more controls

860

6624

1.34

13.48

1.8

1.7

—

Vulvovaginal ulceration/inflammation in other diseases

678

5158

1.44

13.43

1.8

1.7

—

Alcohol dependence

888

6829

1.32

13.43

1.8

1.7

—

Heart failure, strict

883

4836

1.32

13.38

1.7

1.5

—

Diseases of peritoneum

321

2068

1.60

13.37

2.4

1.6

—

Infections of the skin and subcutaneous tissue

3510

30762

1.15

13.33

1.8

1.7

—

Unspecified dementia

101

402

2.29

13.24

1.1

1.2

—

Venous complications and haemorrhoids in pregnancy

230

1436

1.89

13.19

1.8

1.6

—

Fracture of skull and facial bones

1086

8623

1.29

13.19

1.8

1.7

—

4891

34162

0.89

13.12

1.7

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

4891

34162

0.89

13.12

1.7

—

Scleritis

405

2.56

13.10

1.5

1.6

—

Other problems related to primary support group, including family circumstances

1191

9437

1.30

13.08

1.9

1.7

—

Dental pulpitis 2

3788

17044

1.15

13.07

1.7

—

Haemorrhoids and perianal venous thrombosis

824

6288

1.33

13.03

1.7

1.6

—

Inflammatory diseases of prostate (prostatitis)

267

1652

1.65

12.96

1.8

1.7

—

1476

12423

1.29

12.96

1.7

—

Viral hepatitis

503

3614

1.47

12.94

2.0

1.7

—

Dental caries 1

4121

18629

1.14

12.85

1.7

—

Diseases of pulp and periapical tissues, including avohilmo

8019

38215

1.10

12.85

1.7

—

Chronic lower respiratory diseases

7448

43973

0.91

12.83

1.7

—

Giant cell arteritis with polymyalgia rheumatica

311

2.57

12.82

1.1

1.4

—

2891

23080

1.16

12.80

1.8

1.7

—

Disorders of psychological development

1025

11740

0.77

12.78

1.9

1.8

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

4773

37358

0.89

12.77

1.7

—

Chronic ulcer of skin, not elsewhere classified

177

986

1.85

12.77

1.6

—

Dental pulpitis 3

2843

18185

1.21

12.74

1.9

1.8

—

Dental caries 3, only avohilmo

4774

21805

1.13

12.72

1.7

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

392

4474

0.68

12.71

1.4

1.5

—

Infections, IBD-co-morbidities

840

4693

1.33

12.70

1.8

1.7

—

Dental pulpitis 4

8018

38229

1.10

12.69

1.7

—

Diabetic retinopathy

819

3926

1.34

12.68

1.9

1.6

—

Dental pulpitis 1

8018

38241

1.10

12.66

1.7

—

Dental caries, including avohilmo

4114

18622

1.14

12.61

1.7

—

Atrial fibrillation and flutter with reimbursement

470

2085

1.46

12.56

1.4

—

Diaphragmatic hernia

790

6028

1.33

12.49

1.6

—

Other disorders of skin and subcutaneous tissue

2577

20371

1.17

12.45

1.7

1.6

—

Postpartum haemorrhage due to retained placenta

1745

14917

1.25

12.44

1.7

—

Dental pulpitis 2, only avohilmo

3821

17259

1.14

12.35

1.7

—

Bacterial intestinal infections, IBD co-morbidities

625

4642

1.38

12.22

1.7

—

Fungal Sepsis

141

748

1.99

12.17

1.9

1.6

—

Premature separation of placenta [abruptio placentae]

202

1222

1.84

12.12

1.9

1.6

—

Alzheimer disease

255

1179

1.64

12.06

1.1

1.2

—

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

428

2.29

12.03

1.3

1.5

—

Nausea and vomiting

1439

11697

1.23

12.02

1.8

1.7

—

Zoster [herpes zoster]

525

3805

1.41

11.93

1.9

1.6

—

Systemic connective tissue disorders

1378

11332

1.24

11.91

1.5

1.6

—

Other skin changes

555

4067

1.40

11.87

1.8

1.6

—

Iron deficiency

309

2140

1.72

11.87

2.1

1.7

—

Memory loss

186

1073

1.77

11.85

1.5

—

Chronic iridocyclitis

262

1675

1.65

11.84

1.4

1.7

—

Testicular dysfunction

130

678

2.02

11.76

2.0

1.9

—

Oxycodone

764

5657

1.32

11.74

1.7

1.6

—

Ovarian hyperstimulation (induction)

266

1798

1.80

11.74

1.8

1.6

—

Alcohol use disorder, Swedish definition

2490

20009

1.17

11.71

1.8

1.7

—

Dental caries 1, only avohilmo

4176

19017

1.13

11.70

1.7

—

Heart failure and hypertrophic cardiomyopathy

165

3.15

11.67

1.3

1.4

—

Female infertility, tubal origin

368

2552

1.53

11.63

1.7

1.6

—

Asthma (only as main-diagnosis)

4913

26720

1.12

11.62

1.7

—

Dysplasia of cervi uteri

2604

17628

1.18

11.62

1.7

—

Assault by bodily force

621

4710

1.39

11.62

2.0

1.8

—

Other diseases of lip and oral mucosa

499

3604

1.41

11.60

1.7

1.6

—

Disorders of other endocrine glands

2667

22913

1.16

11.57

1.8

1.7

—

Other encephalitis

167

962

1.88

11.52

1.4

1.7

—

Obesity due to excess calories

3095

27334

1.15

11.51

1.7

—

Obesity and other hyperalimentation

4151

36890

1.13

11.50

1.7

—

Disorders of lacrimal system

1620

13574

1.21

11.49

1.7

1.6

—

Retinal detachments and breaks

670

5055

1.34

11.49

1.6

1.5

—

Agranulocytosis

397

2767

1.48

11.48

1.6

—

Dental pulpitis 1, only avohilmo

8071

38870

1.09

11.48

1.7

—

Other bacterial intestinal infections

632

4751

1.36

11.45

1.7

—

Acute alcohol intoxication, ICD10

1087

8791

1.27

11.44

1.8

1.7

—

Complications of medical and surgical care

3253

27271

1.14

11.44

1.7

1.6

—

Other disorders of lacrimal gland

1322

10878

1.24

11.41

1.7

1.6

—

Obesity

4140

36833

1.13

11.40

1.7

—

Implicit fungal Sepsis

131

694

1.99

11.40

1.9

1.6

—

Used for control exclusion in common control thyroid runs

8179

38271

1.09

11.39

1.7

—

Dental pulpitis 4, only avohilmo

8051

38783

1.09

11.35

1.7

—

Diseases of the eye and adnexa

7626

35187

1.10

11.30

1.8

1.7

—

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

168

965

1.83

11.27

2.3

1.6

—

Myeloid leukaemia

430

2.27

11.24

1.5

1.6

—

Asthma (mode)

5399

26890

1.11

11.22

1.7

—

Other and unspecified disorders of vitreous body

646

4838

1.34

11.19

1.5

1.4

—

Vitreous haemorrhage

305

2025

1.55

11.18

2.2

1.6

—

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

290

2.52

11.14

1.2

1.4

—

ILD, hospital admissions 3, with pneumonia sepsis

146

799

1.87

11.09

1.5

—

Myeloid leukaemia

433

2.25

11.05

1.5

1.7

—

Autoimmune diseases

8382

39598

1.09

11.05

1.7

—

Mental retardation, wide definition

1763

0.47

11.04

2.3

1.8

—

All influenza

1134

9227

1.25

11.02

1.8

1.7

—

Haemophagocytic lymphohistiocytosis

9.69

10.98

2.9

1.8

—

Encephalitis

174

1028

1.83

10.97

1.4

1.7

—

Hypertensive Heart Disease

303

1630

1.53

10.89

2.1

1.4

—

Polymyalgia rheumatica

162

919

1.79

10.84

1.2

1.4

—

Personal history of certain other diseases

303

2142

1.70

10.84

2.0

1.7

—

Maltreatment syndromes

538

4072

1.43

10.81

2.0

1.8

—

Disorders of male genital organs in diseases classified elsewhere

102

3.88

10.80

1.6

1.9

—

Symptoms and signs involving the circulatory and respiratory systems

8454

39265

1.09

10.79

1.8

1.7

—

Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

251

1678

1.72

10.76

1.9

1.6

—

Sarcoidosis

407

2879

1.45

10.75

1.5

1.6

—

Mental retardation

1730

0.47

10.74

2.3

1.8

—

Arthrosis

1910

12335

0.84

10.72

1.5

1.6

—

Family history of certain disabilities and chronic diseases leading to disablement

479

3581

1.45

10.55

2.1

1.7

—

Depression medications

4313

19598

1.13

10.53

1.8

1.7

—

Other and unspecified iridocyclitis

230

1475

1.65

10.39

1.4

1.7

—

Asthma (only as main-diagnosis), excluding more controls

4901

26480

1.11

10.37

1.7

—

Cutaneous abscess, furuncle and carbuncle

1475

12423

1.21

10.33

1.8

1.7

—

Other noninflammatory disorders of vulva and perineum

723

5685

1.33

10.31

1.7

—

Maternal care for cervical incompetence

333

2342

1.54

10.30

1.9

1.6

—

Testicular hypofunction

113

590

2.01

10.26

2.1

1.9

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

1898

14040

0.85

10.25

1.7

1.6

—

Oxicams

852

6099

0.78

10.14

1.6

1.7

—

Benign neoplasm: Colon

889

6933

1.27

10.04

1.5

—

Pediculosis, acariasis and other infestations

330

2301

1.51

10.01

2.1

1.7

—

Streptococcal septicaemia

253

1658

1.57

9.91

1.8

1.7

—

All-cause Heart Failure

835

4741

1.28

9.86

1.7

1.5

—

3056

24321

1.14

9.82

1.8

1.7

—

Endocarditis

110

577

1.99

9.79

1.6

—

Amputation

168

994

1.72

9.79

2.3

1.5

—

Conductive and sensorineural hearing loss

1727

14023

0.85

9.78

1.5

1.6

—

Other and unspecified effects of external causes

2084

18165

1.17

9.78

1.8

1.7

—

Artificial joint operation, meniscal resection

2040

15717

0.86

9.76

1.5

1.6

—

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

600

4656

1.36

9.69

2.0

1.8

—

Benign neoplasm of colon, rectum, anus and anal canal

1132

8377

1.23

9.68

1.6

1.5

—

Transport accidents

3594

28667

1.13

9.67

1.8

1.7

—

Implicit Sepsis

2870

19726

1.14

9.66

1.7

1.6

—

Dementia in Alzheimer disease

132

618

1.84

9.65

1.0

1.2

—

Other spirochaetal diseases

853

6824

1.27

9.64

1.6

1.7

—

Other/unspecified dorsalgia

1944

16723

1.17

9.63

1.7

—

Malignant neoplasm of prostate

273

2565

0.67

9.60

1.3

1.4

—

Benzodiazepine use

5251

40801

0.91

9.55

1.7

—

Ulcer of lower limb, not elsewhere classified

253

1665

1.54

9.54

1.9

1.6

—

Scleritis and episcleritis

297

2045

1.52

9.52

1.5

1.7

—

Cardiomyopathy

365

2585

1.43

9.46

1.4

1.6

—

Inflammatory diseases of the central nervous system

392

2837

1.43

9.45

1.5

1.7

—

Other diseases of pericardium

128

713

1.86

9.44

1.7

1.6

—

Abnormal findings on diagnostic imaging of central nervous system

259

1746

1.57

9.43

1.6

1.7

—

Hypo-osmolality and hyponatraemia

307

2100

1.48

9.41

1.7

1.5

—

Diabetic retinopathy, excluding more controls

737

3239

1.30

9.38

1.9

1.7

—

Undefined dementia

102

479

1.98

9.36

1.1

1.2

—

Macular pucker

175

1059

1.67

9.35

1.5

1.3

—

Mental and behavioural disorders due to cannabinoids

318

2271

1.54

9.32

2.0

1.9

—

Alcohol abuse, main dg

860

6951

1.27

9.27

1.8

1.7

—

Enterocolitis due to Clostridium difficile

302

2080

1.49

9.27

1.7

1.6

—

Symptoms and signs involving speech and voice

1120

9263

1.23

9.22

1.6

—

Fluid overload

5.17

9.22

2.2

2.1

—

Diagnoses used for exclusion with ILD

633

4902

1.31

9.19

1.5

1.6

—

Explicit bacterial Sepsis

396

2876

1.41

9.17

1.8

1.7

—

Mild mental retardation

1180

0.42

9.17

2.6

1.8

—

Sleep apnoea, including avohilmo

3202

23251

0.89

9.17

1.7

—

Asthma

5437

26720

1.10

9.16

1.7

—

Unspecified abortion

188

1177

1.66

9.14

1.9

1.5

—

Spinal stenosis

755

4660

1.28

9.10

1.3

1.5

—

Amputation of toe

125

697

1.83

9.05

2.4

1.5

—

Mental retardation, excluding more controls

1609

0.50

9.03

2.3

1.7

—

Disorders of calcium metabolism

186

1164

1.65

8.98

1.8

1.6

—

Polyuria

629

4889

1.31

8.98

1.7

1.6

—

Other surgical follow-up care

242

1636

1.59

8.97

1.9

1.7

—

Redundant prepuce, phimosis and paraphimosis

663

5168

1.30

8.93

2.3

1.9

—

Atrial fibrillation and flutter

820

4262

1.27

8.91

1.5

1.6

—

Retinal detachment with retinal break

242

1603

1.53

8.90

1.6

1.5

—

Other headache syndromes

2645

23506

1.14

8.90

1.7

—

Lyme disease

826

6649

1.26

8.88

1.6

1.7

—

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

116

2044

0.56

8.87

1.3

1.5

—

Hernia

3511

26445

0.89

8.83

1.7

—

Degeneration of macula and posterior pole

559

3508

1.32

8.83

1.5

1.4

—

Superficial injury of head

1118

9309

1.22

8.82

1.8

1.7

—

Other soft tissue disorders, not elsewhere classified

5943

39730

0.92

8.79

1.7

—

Asthma, excluding more controls

5412

26480

1.10

8.78

1.7

—

Excessive, frequent and irregular menstruation

3650

22397

0.89

8.76

1.7

—

Use of donepezil

160

923

1.68

8.76

1.2

—

Viral pneumonia

568

4391

1.33

8.75

1.9

1.7

—

Symptoms and signs involving the nervous and musculoskeletal systems

2656

23585

1.14

8.75

1.6

1.7

—

Osteonecrosis

153

917

1.72

8.74

1.6

1.5

—

Peripheral artery operations in Hilmo

193

1219

1.60

8.70

2.3

1.4

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

4349

33433

0.90

8.70

1.6

1.7

—

Lichen simplex chronicus and prurigo

205

1326

1.60

8.65

1.8

1.6

—

Wide developmental disorders

177

2673

0.61

8.61

2.1

1.8

—

Umbilical hernia

993

8187

1.23

8.54

1.8

1.6

—

Seborrhoeic keratosis

366

2643

1.40

8.49

1.7

1.5

—

Impotence

113

625

1.86

8.48

1.8

—

Aortic aneurysm

324

2249

1.43

8.47

1.5

—

Cardiomyopathies, Primary/intrinsic

245

1646

1.51

8.45

1.3

1.6

—

Amyloidosis, other/unspecified

168

2.75

8.40

1.7

1.5

—

Voice disturbances

927

7606

1.24

8.37

1.6

—

Disorders of mineral metabolism

247

1673

1.52

8.37

1.9

1.6

—

Frontotemporal dementia, wide, incl. Pick's disease

4.86

8.29

1.1

1.3

—

Lichen sclerosus et atrophicus

281

1954

1.47

8.29

1.7

1.6

—

Venous thromboembolism

1385

11433

1.19

8.21

1.6

—

ILD-related respiratory insufficiency

274

2.30

8.16

1.5

—

Nephrotic syndrome

141

851

1.75

8.15

2.6

1.7

—

Malignant neoplasm of digestive organs

285

3982

0.70

8.14

1.4

1.5

—

Mental and behavioural disorders due to sedatives or hypnotics

398

2973

1.39

8.13

1.9

1.7

—

Direct fill therapy

703

5643

1.28

8.12

1.9

1.7

—

Paracetamol of NSAID medication

1973

8678

1.17

8.11

1.8

1.7

—

Renal tubulo-interstitial disorders in diseases classified elsewhere

192

2.68

8.08

2.3

1.7

—

Other benign neoplasms of skin

1175

9892

1.20

8.01

1.8

1.6

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

361

2647

1.40

8.01

1.7

1.6

—

L04AX Other immunosuppressants

2664

23809

1.13

7.98

1.6

1.7

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

2394

20810

1.14

7.98

1.7

—

Other cataract

775

4823

1.25

7.96

1.7

1.5

—

Senile cataract

1000

5104

1.22

7.89

1.5

1.4

—

Thoracic aortic aneurysm

224

1500

1.52

7.87

1.6

—

Small fibre neuropathy

436

2.02

7.85

1.5

1.6

—

Herpesviral [herpes simplex] infections

591

4673

1.30

7.80

1.8

1.7

—

Intracranial trauma

3666

30068

0.90

7.79

1.8

1.7

—

Scabies

275

1952

1.49

7.79

2.0

1.7

—

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

4.02

7.76

2.4

1.7

—

Gastrointestinal diseases

6264

29165

1.09

7.76

1.8

1.7

—

Viral infections of the central nervous system

396

2975

1.38

7.75

1.7

—

Puerperal sepsis

542

4235

1.31

7.74

1.7

1.6

—

Other arrhythmias

2405

20691

0.88

7.73

1.6

—

Osteopathy in diseases classified elsewhere

3.42

7.71

1.9

1.5

—

Polyp of the female genital tract

1159

7990

0.83

7.71

1.6

—

Lower back pain or/and sciatica

5792

43275

0.92

7.69

1.7

—

Visual disturbances and blindness

2343

20841

1.14

7.67

1.7

—

Respiratory insufficiency

112

634

1.79

7.67

1.5

1.4

—

Dermatophytosis

387

2882

1.37

7.66

1.8

1.7

—

Insomnia

1121

9510

1.21

7.65

1.8

1.7

—

Carrier of infectious disease

190

1274

1.63

7.59

1.9

1.7

—

Cardiomyopathy (excluding other)

249

1717

1.47

7.58

1.4

1.6

—

Other and unspecified vascular occlusions

135

811

1.69

7.55

1.4

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

345

2520

1.38

7.51

1.5

—

Other extrapyramidal and movement disorders in other diseases

649

5185

1.27

7.51

1.7

1.6

—

Traumatic subdural haemorrhage

187

1196

1.56

7.48

1.5

1.6

—

Varicose veins of other sites

207

1388

1.53

7.44

1.9

1.8

—

Metabolic disorders

3131

21538

0.90

7.43

1.7

1.6

—

Wide developmental disorders, excluding more controls

177

2567

0.63

7.41

2.1

1.8

—

Nonorganic sleeping disorders, excluding more controls

1407

12188

1.18

7.40

1.8

1.7

—

Spondylopathies

2218

15212

0.88

7.40

1.5

1.6

—

Idiopathic gout

132

794

1.69

7.37

1.7

1.4

—

Lymphoid leukaemia

153

962

1.64

7.33

1.3

1.6

—

Dentofacial anomalies [including malocclusion]

1951

17072

1.15

7.31

1.7

—

Charcot foot

290

2.23

7.30

2.1

1.6

—

Malaise and fatigue

2100

15482

1.14

7.29

1.6

—

Secondary thrombocytopenia

266

2.32

7.29

1.5

1.7

—

Cardiodefibrillation

486

3742

1.31

7.28

1.4

1.5

—

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

182

2741

0.66

7.26

1.3

1.5

—

2837

25421

1.12

7.25

1.7

—

Diseases of the respiratory system

4924

22750

1.09

7.23

1.7

—

Actinic keratosis

359

2516

1.36

7.21

1.5

1.3

—

243

1485

1.46

7.16

1.4

1.2

—

Embedded and impacted teeth

4021

31638

1.11

7.15

1.8

—

Chronic gastritis

517

4034

1.29

7.14

1.6

1.5

—

Malignant neoplasm of testis, excluding all cancers (controls excluding all cancers)

425

1.99

7.11

1.9

2.0

—

Iron deficiency anaemia

1528

13147

1.16

7.10

1.7

1.6

—

Pacemaker

435

3222

1.32

7.10

1.4

1.5

—

Obesity related asthma

1211

10347

1.18

7.06

1.7

1.6

—

Hypothyroidism, drug reimbursement

782

6769

0.81

7.06

1.6

—

Irritable bowel syndrome

1656

14521

1.16

7.06

1.8

1.7

—

Autism

149

2222

0.61

7.05

2.1

1.9

—

Type 1 diabetes, strict definition

609

7446

0.78

7.04

1.7

1.8

—

Nutritional anaemias

1683

14324

1.15

7.03

1.7

1.6

—

Osteoporosis

399

2871

1.34

7.01

1.6

1.5

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

1924

16904

1.14

6.99

1.8

1.7

—

Tramadol

3136

22232

0.90

6.99

1.7

1.6

—

Autism spe

142

2133

0.61

6.96

2.1

1.9

—

Use of rivastigmine

121

719

1.69

6.96

1.1

1.2

—

L02BA Anti-estrogens

191

2817

0.67

6.95

1.3

1.5

—

Malignant neoplasm of testis

394

2.03

6.95

1.9

2.0

—

Pain, not elsewhere classified

1490

12979

1.17

6.93

1.7

—

Disturbances of skin sensation

1732

15266

1.16

6.92

1.7

—

169

1033

1.56

6.92

1.4

1.2

—

Benign neoplasm: Sigmoid colon

274

1956

1.42

6.91

1.4

1.5

—

Disorders of skin appendages

3340

30497

1.11

6.90

1.8

1.7

—

Second line medication for Crohn's disease

2798

25290

1.12

6.90

1.6

1.7

—

Asthma-related pneumonia

1287

11052

1.18

6.90

1.7

—

Lymphoid leukaemia

153

978

1.61

6.87

1.3

1.6

—

Asthma-related pneumonia or sepsis

1293

11111

1.17

6.87

1.7

—

Asthma, hospital admissions 3, pneumonia

1293

11111

1.17

6.87

1.7

—

Visual disturbances

2221

19843

1.13

6.84

1.7

—

Asthma, hospital admission 2, infections

3286

29474

1.11

6.83

1.7

—

Asthma-related infections

3286

29474

1.11

6.83

1.7

—

Inguinal hernia

1853

14168

0.88

6.81

1.7

—

Abnormalities of gait and mobility

281

2027

1.41

6.79

1.4

1.6

—

Chronic tubulo-interstitial nephritis

118

710

1.72

6.77

2.2

1.6

—

Other maltreatment syndromes

209

1452

1.53

6.77

1.9

1.8

—

Urticaria and erythema

2368

21287

1.13

6.75

1.7

—

Hernia of abdominal wall

1420

12317

1.16

6.74

1.8

1.6

—

Macular cyst

238

2.26

6.74

1.3

1.4

—

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

231

1983

0.69

6.73

1.4

1.5

—

Type1 diabetes, definitions combined, early onset

547

6694

0.77

6.70

1.8

—

Skin changes due to chronic exposure to nonionizing radiation

383

2734

1.33

6.68

1.5

1.3

—

Open wound of head

2101

18437

1.13

6.65

1.8

1.7

—

Benign neoplasm: Colon, unspecified

365

2731

1.34

6.64

1.6

1.5

—

Circumscribed brain atrophy

140

2.66

6.64

1.3

—

Unspecified haematuria

970

6982

1.20

6.63

1.8

1.6

—

Arthropathies in other diseases classified elsewhere

133

833

1.66

6.63

1.9

1.7

—

Viral pneumonia (known virus, not influenza)

106

630

1.78

6.61

2.3

1.7

—

malignant neoplasm of male genital organs

347

2939

0.75

6.53

1.5

—

Non-selective monoamine reuptake inhibitors

993

8133

1.19

6.53

1.5

1.6

—

Deviated nasal septum

1077

9165

1.19

6.52

1.6

1.7

—

Pulmonary heart disease, diseases of pulmonary circulation

655

5318

1.24

6.48

1.5

1.6

—

Cerebrovascular diseases (FINNGEN)

986

5943

1.20

6.45

1.6

—

Sleep disorders

1533

13494

1.16

6.43

1.8

1.7

—

Pneumonia due to other infectious organisms, not elsewhere classified

123

763

1.68

6.42

1.5

1.7

—

Poisoning by drugs, medicaments and biological substances

1878

16747

1.14

6.42

1.9

1.7

—

Drug-induced cataract

491

1.86

6.42

2.2

1.6

—

Presence of cardiac and vascular implants and grafts

656

4017

1.24

6.41

1.5

1.4

—

Type 1 diabetes, definitions combined

677

8128

0.80

6.38

1.7

1.8

—

Special screening examination for other diseases and disorders

512

4086

1.29

6.37

1.8

1.6

—

Other benign neoplasms of skin

1175

9903

1.18

6.36

1.8

1.6

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

5001

36648

0.92

6.36

1.7

—

Mental and behavioural disorders due to use of other stimulants, including caffeine

274

2041

1.45

6.33

2.0

1.8

—

Viral encephalitis, not elsewhere classified/unspecified

586

1.80

6.32

1.4

1.7

—

Acute sinusitis

3740

32121

1.10

6.32

1.7

—

Chronic sinusitis

2165

19400

1.13

6.31

1.6

1.7

—

Unspecified nephritic syndrome

442

1.90

6.30

2.4

1.6

—

Type 1 diabetes, strict definition, subgroup 1

600

7255

0.79

6.29

1.7

1.8

—

Recurring oral aphthae, including avohilmo

701

5794

1.24

6.28

1.8

1.7

—

Type 1 diabetes, strict (exclude DM2)

677

8114

0.80

6.28

1.7

1.8

—

Retinal vascular disorders

172

1146

1.52

6.27

1.4

—

Other disorders of eyelid

753

6008

1.22

6.26

1.5

—

Restless leg syndrome

398

3073

1.32

6.26

1.7

1.6

—

Retinal vascular occlusion

170

1131

1.52

6.25

1.4

—

Atrophic disorders of skin

527

4216

1.27

6.24

1.7

—

Temporomandibular joint disorders

1112

9584

1.19

6.20

1.7

—

Alzheimer’s disease (Atypical or mixed), excluding more controls

209

2.17

6.20

1.1

1.2

—

Other and unspecified iron deficiency

1274

11047

1.17

6.20

1.7

1.6

—

Benign neoplasm: Sigmoid colon

274

1995

1.39

6.20

1.4

1.5

—

Follicular lymphoma

463

1.84

6.19

1.4

1.5

—

Other specified and unspecified retinal disorders

108

653

1.72

6.18

1.7

1.6

—

Hyperplasia of prostate

549

2482

1.27

6.18

1.8

1.5

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

3947

35881

1.09

6.17

1.7

—

Spondylopathies in diseases classified elsewhere

111

2.84

6.16

1.4

1.5

—

Heart failure and bmi 25plus

466

2506

1.29

6.16

1.6

1.4

—

Benign neoplasm: Colon, unspecified

365

2778

1.33

6.15

1.6

1.5

—

Extrapyramidal and movement disorders

908

7658

1.20

6.14

1.6

—

Fenamates

857

6844

0.83

6.12

1.6

1.7

—

Other viral diseases, not elsewhere classified

1122

9658

1.18

6.11

1.8

1.7

—

Frontotemporal dementia

4.81

6.10

1.0

1.4

—

Dependence on enabling machines and devices, not elsewhere classified

237

2.25

6.09

3.7

1.8

—

Disorders of lens

1346

7351

1.16

6.06

1.7

1.5

—

Sensorineural hearing loss

1447

11584

0.87

6.05

1.5

1.6

—

Injuries to the knee and lower leg

7262

44083

0.94

6.04

1.7

—

Prurigo nodularis

375

1.94

6.03

1.4

1.5

—

Dorsopathies

8230

39707

1.07

6.02

1.7

—

Conjunctivitis (acute, non atopic)

1737

15415

1.14

5.94

1.8

1.7

—

Schizophrenia

555

6812

0.80

5.91

1.7

—

Benign neoplasm: Rectum, anus and anal canal

315

2363

1.35

5.90

1.6

1.5

—

Non-ischemic cardiomyopathy

437

2802

1.29

5.90

1.6

1.5

—

Wet age-related macular degeneration

133

832

1.58

5.89

1.4

1.2

—

Alzheimer’s disease (Early onset), excluding more controls

162

2.36

5.88

1.1

1.2

—

466

3459

1.27

5.87

1.6

1.4

—

Pain associated with micturition

500

4013

1.27

5.86

1.9

1.7

—

Other specified/unspecified necrotizing vasculopathies

248

2.18

5.86

2.0

1.6

—

Tinnitus

724

6020

1.22

5.85

1.6

—

Follicular lymphoma, hilmo

472

1.80

5.83

1.4

—

Phlebitis and thrombophlebitis (not including DVT)

662

5459

1.23

5.81

1.7

1.6

—

Early onset COPD, excluding more controls

403

3135

1.30

5.79

1.6

—

Childhood allergy (age < 16)

2655

23659

0.89

5.78

1.8

—

Amyloidosis

228

2.18

5.75

1.7

1.6

—

Other disorders of male genital organs

114

712

1.65

5.74

2.0

—

Other local infections of skin and subcutaneous tissue

400

3135

1.31

5.72

1.9

1.7

—

Erectile dysfunction

107

654

1.66

5.72

1.4

—

Amputation of ankle bones

222

2.19

5.69

2.4

1.6

—

Keratitis

1703

15165

1.14

5.68

1.8

1.7

—

Unspecified acute lower respiratory infection

616

5069

1.24

5.67

1.9

1.7

—

DVT of lower extremities and pulmonary embolism

917

7768

1.19

5.66

1.6

—

296

2308

1.44

5.64

1.9

1.7

—

Osteoporosis with pathological fracture (FG)

366

1.88

5.63

1.3

1.4

—

Disorders of the thyroid gland

6373

39205

1.07

5.61

1.7

—

Cardiomyopathy in other diseases

4.76

5.61

1.4

1.3

—

Pulmonary embolism

594

4856

1.23

5.59

1.5

1.6

—

Pulmonary heart disease

594

4856

1.23

5.59

1.5

1.6

—

Abnormal findings on examination of urine, without diagnosis

204

1458

1.46

5.57

1.9

1.7

—

Assault by unspecified means

163

1133

1.55

5.54

2.1

1.8

—

Intracranial injury

3227

28695

1.10

5.54

1.8

1.7

—

Delayed milestone in childhood

862

0.50

5.54

1.7

1.8

—

Moderate mental retardation

266

0.20

5.51

3.2

1.8

—

Other pleural conditions

153

1025

1.51

5.51

1.6

1.5

—

Recurring oral aphthae

211

1520

1.44

5.50

1.7

—

Urticaria

2043

18455

1.12

5.49

1.7

—

Colorectal adenocarcinoma

109

1718

0.63

5.49

1.3

1.4

—

Benign neoplasm: Rectum, anus and anal canal

315

2391

1.33

5.48

1.6

1.5

—

Use of pramipexole

449

3572

1.27

5.47

1.7

1.5

—

Myocarditis

185

1297

1.47

5.46

1.7

—

Other and unspecified coagulation defects

301

2305

1.37

5.46

1.6

1.7

—

Autism spe, excluding more controls

142

2033

0.64

5.45

2.1

1.8

—

Osteonecrosis due to drugs

156

2.44

5.44

1.4

1.6

—

Episcleritis

237

1743

1.41

5.43

1.5

1.7

—

Diseases of the musculoskeletal system and connective tissue

5917

27907

1.07

5.43

1.7

—

Leukaemia of unspecified cell type

177

2.38

5.41

1.3

1.8

—

Procedures for purposes other than remedying health state

123

801

1.61

5.40

1.8

1.6

—

Invasive ventilation

223

1618

1.41

5.40

1.8

1.7

—

Tobacco use

306

2351

1.36

5.39

1.7

—

Peripheral arterial reconstruction

176

1216

1.46

5.38

2.0

1.4

—

All dysplastic lesions of the cervix uteri, vagina or vulva

2755

25181

1.11

5.37

1.7

—

Other inflammation of eyelid

493

3989

1.26

5.37

1.8

1.7

—

Fracture of rib(s), sternum and thoracic spine

754

6341

1.20

5.36

1.6

1.7

—

Acquired haemolytic anaemia

550

1.73

5.35

1.6

1.7

—

Isolated proteinuria

149

1015

1.55

5.35

2.0

1.7

—

Leukaemia of unspecified cell type

178

2.37

5.34

1.3

1.8

—

Malignant neoplasm of bronchus and lung

1286

0.59

5.33

1.1

1.3

—

Hypertensive diseases

2700

16751

0.91

5.31

1.8

1.6

—

Other acute lower respiratory infections

2846

24910

1.10

5.29

1.8

1.7

—

Fissure and fistula of anal and rectal regions

924

7925

1.18

5.29

1.8

1.7

—

Pericarditis

104

649

1.65

5.28

1.6

—

Human immunodeficiency virus [HIV] disease resulting in other specified diseases

14.24

5.28

2.2

1.5

—

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

229

3057

0.73

5.28

1.4

1.5

—

Other symptoms and signs involving the nervous and musculoskeletal systems

2035

18378

1.12

5.27

1.7

—

Complications specific to multiple gestation

311

2.26

5.25

1.6

—

Adjustment and management of implanted device

305

2322

1.33

5.22

1.3

1.5

—

Nonorganic sleeping disorders

1407

12506

1.15

5.21

1.8

1.7

—

Soft tissue disorders related to use, overuse and pressure

732

6160

1.20

5.19

1.7

1.6

—

Pneumonia, organism unspecified

4164

32328

0.93

5.18

1.7

—

Mental and behavioural disorders due to tobacco

328

2543

1.32

5.16

1.8

1.7

—

Hydrocele

212

1530

1.40

5.16

2.2

1.8

—

Viral warts

653

5488

1.22

5.15

1.9

1.7

—

Poisoning by medicine

1706

15342

1.13

5.15

1.9

1.7

—

Cardiovascular diseases

6622

38103

0.94

5.15

1.8

1.7

—

Stomatitis and related lesions

440

3546

1.27

5.13

1.8

1.6

—

Hypertension

2696

16691

0.91

5.11

1.8

1.6

—

Osteomyelitis

175

1229

1.46

5.11

1.9

1.6

—

Other autoimmune haemolytic anaemias

194

2.24

5.09

1.6

—

Reactive arthropathies

377

2980

1.29

5.09

1.7

—

Other disorders of bladder

281

2128

1.34

5.09

1.8

1.6

—

Other and unspecified local infections of skin and subcutaneous tissue

383

3035

1.29

5.08

1.9

1.7

—

Seborrhoeic dermatitis

332

2581

1.31

5.07

1.8

1.7

—

Chronic conjunctivitis

137

926

1.55

5.06

1.7

1.6

—

Smoking dependency

328

2551

1.32

5.05

1.8

1.7

—

Bipolar affective disorders

1569

14068

1.14

5.05

1.9

1.7

—

Other infectious diseases

254

1903

1.36

5.05

1.9

1.6

—

Other CVD

310

2378

1.32

5.03

1.6

1.5

—

Myalgia

1366

12124

1.14

5.00

1.7

—

Acute bronchitis

1864

16463

1.12

4.99

1.7

—

Other arthritis (FG)

1322

11688

1.14

4.97

1.6

1.7

—

Manic episode

197

1437

1.44

4.97

1.7

—

Drug-induced neutropenia

198

1430

1.42

4.95

1.5

1.6

—

Atherosclerosis, excluding cerebral and coronary sclerosis

462

2968

1.25

4.94

1.8

1.4

—

Reactive arthropathies, FINNGEN

331

2589

1.31

4.93

1.7

—

Glucosamine medication

560

3667

1.22

4.93

1.2

1.4

—

Glaucoma

987

7483

1.16

4.92

1.5

—

Volume depletion

225

1658

1.38

4.91

1.8

1.6

—

Other diseases of pleura

811

6116

1.18

4.90

1.6

—

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

109

1671

0.65

4.89

1.3

1.4

—

Other symptoms and signs involving the digestive system and abdomen

586

4870

1.22

4.88

1.7

1.6

—

Continuous positive airway pressure

396

2710

1.27

4.87

1.5

1.6

—

Speech and linguistic disorders

747

8309

0.83

4.87

1.9

1.8

—

Hypotension

260

1957

1.34

4.85

1.6

1.5

—

Spondylosis

1066

7949

1.16

4.85

1.5

—

Disorders of thyroid, IBD co-morbidities

1277

10499

0.87

4.84

1.6

1.7

—

717

0.47

4.84

1.1

1.5

—

Neurological diseases, wide definition

4043

18938

1.09

4.84

1.8

1.7

—

Papulosquamous disorders

1318

11667

1.14

4.81

1.6

—

Injuries to the wrist and hand

6518

44728

1.06

4.81

1.7

—

Vocal cord dysfunction

613

4760

1.21

4.80

1.7

1.6

—

Immunodeficiency with predominantly antibody defects

134

916

1.54

4.78

1.7

—

Faecal incontinence

198

1436

1.40

4.77

1.6

1.5

—

Traumatic subarachnoid haemorrhage

479

1.71

4.77

1.7

1.6

—

Complications of surgical and medical care, not elsewhere classified

4596

35144

0.93

4.74

1.7

—

Allergic conjunctivitis

4090

37677

1.08

4.73

1.7

—

Cellulitis

914

7916

1.17

4.73

1.9

1.7

—

Primary open-angle glaucoma

328

2489

1.29

4.72

1.3

1.4

—

Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms

10.53

4.70

2.0

1.5

—

Postmenopausal bleeding

323

1365

1.31

4.69

1.3

1.4

—

Mixed specific developmental disorders

122

1628

0.65

4.68

1.9

1.8

—

Alcohol-induced chronic pancreatitis

147

1016

1.48

4.67

1.5

1.7

—

ILD medications: azathioprine

842

7270

1.18

4.67

1.8

1.7

—

Radiculopathy

369

2929

1.27

4.66

1.5

1.6

—

Ptosis of eyelid

198

1441

1.39

4.66

1.5

—

Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma

4.72

4.66

1.6

1.5

—

Neovascular glaucoma

121

807

1.54

4.66

1.7

1.6

—

Chronic pancreatitis

253

1913

1.34

4.65

1.7

1.6

—

Calcific aortic valvular stenosis, including rheumatic fever

313

2376

1.30

4.63

1.6

1.4

—

Other and unspecified immunodeficiencies with predominantly antibody defects

393

1.83

4.59

1.7

—

Other external causes of accidental injury

6438

30528

1.06

4.58

1.7

—

Assault by other specified means

524

1.76

4.57

1.9

1.8

—

Hypertensive diseases (excluding secondary)

2312

14708

0.91

4.56

1.8

1.6

—

Operations 2 for CAVS

311

2366

1.29

4.56

1.6

1.4

—

Calcific aortic valvular stenosis, diagnosis (helper)

311

2366

1.29

4.56

1.6

1.4

—

Unspecified fall

2244

20353

1.10

4.56

1.8

1.7

—

Accidents

6436

30528

1.06

4.53

1.7

—

Glaucoma secondary to other eye disorders

121

813

1.53

4.51

1.7

1.6

—

Erysipelas

1307

10574

1.13

4.51

1.8

1.6

—

Other heart diseases

2478

17823

0.91

4.50

1.7

—

Abnormal findings on diagnostic imaging of other body structures

351

2791

1.28

4.46

1.6

—

Diabetic neuropathy

218

1616

1.36

4.44

2.0

1.6

—

Personality disorders, excluding more controls

2296

21121

1.10

4.43

1.9

1.7

—

Behavioural syndromes associated with physiological disturbances and physical factors

3018

28067

1.09

4.43

1.9

1.7

—

All dysplastic lesions of the cervix uteri

2628

24311

1.10

4.42

1.7

—

Lichen ruber planus, wide definition including periferal and oral lichen planus

486

4002

1.23

4.42

1.6

—

Psoriasis vulgaris

674

5730

1.19

4.42

1.7

—

Neurological diseases

7594

36406

1.06

4.41

1.7

—

Blepharochalasis

351

2786

1.27

4.39

1.4

—

Haemolytic anaemias

149

1055

1.47

4.38

1.6

1.7

—

Calcific aortic valvular stenosis

312

2389

1.28

4.37

1.6

1.4

—

Calcific aortic valvular stenosis, operated

312

2389

1.28

4.37

1.6

1.4

—

Other and unspecified disorders of orbit

136

2.46

4.33

1.6

1.7

—

Amputation of foot

219

2.01

4.33

2.7

1.4

—

Alopecia areata

184

1365

1.43

4.33

1.6

1.7

—

Benign neoplasm: Skin of eyelid, including canthus

329

2603

1.28

4.32

1.6

—

Peripheral artery disease

563

3775

1.21

4.32

1.9

1.5

—

Spondylolisthesis/Spondylolysis

465

3823

1.23

4.32

1.5

1.6

—

Kela-code for behavioural disturbances in mental retardation

215

0.22

4.32

1.4

1.7

—

Endometriosis of ovary

1059

9327

1.15

4.31

1.7

1.6

—

Injuries to the thorax

1561

14049

1.12

4.31

1.7

—

Hyperhidrosis

246

1908

1.36

4.31

1.8

1.7

—

Special screening examination for neoplasms

626

1.58

4.30

2.3

1.5

—

Mental and behavioural disorders due to opioids

330

2659

1.31

4.29

1.8

—

Lack of expected normal physiological development

176

2031

0.70

4.29

1.8

—

Other disorders of veins

1099

9683

1.14

4.28

1.6

—

Abnormal blood-pressure reading, without diagnosis

192

1422

1.39

4.28

1.7

—

Pure hypercholesterolaemia

1487

8920

1.12

4.28

1.6

—

Glaucoma suspect

641

5426

1.19

4.28

1.6

1.5

—

Undetermined asthma, excluding more controls

539

4508

1.21

4.27

1.6

1.7

—

Diverticular disease of intestine

1301

7665

1.13

4.27

1.5

—

Undetermined asthma

539

4509

1.21

4.27

1.6

1.7

—

Other functional intestinal disorders

1818

15717

1.11

4.25

1.7

—

Toxic effects of substances chiefly nonmedicinal as to source

691

5935

1.19

4.24

1.8

—

Glaucoma, exfoliation

101

657

1.55

4.24

1.1

1.3

—

Chronic inflammatory disorders of orbit

3.00

4.24

1.5

1.6

—

Other specified disorders of kidney and ureter

112

754

1.54

4.21

1.9

1.6

—

Malignant neoplasm of breast, HER-negative

226

2966

0.75

4.21

1.4

1.5

—

Benign neoplasm: Rectum

258

1984

1.31

4.20

1.6

1.5

—

Immunodeficiencies

211

1592

1.37

4.20

1.7

—

Rash and other nonspecific skin eruption

382

3099

1.26

4.19

1.7

1.6

—

Monoamine oxidase A inhibitors

339

2706

1.27

4.19

1.9

1.6

—

Post-traumatic stress disorder

1039

9280

1.17

4.15

2.0

1.7

—

Superficial injury of abdomen, lower back and pelvis

938

8247

1.16

4.15

1.8

1.7

—

Azathioprine

842

7342

1.17

4.14

1.8

1.7

—

Chronic rhinitis, nasopharyngitis and pharyngitis

1579

14280

1.12

4.13

1.7

—

Colon adenocarcinoma

935

0.57

4.12

1.3

1.4

—

Gastric ulcer

287

2244

1.29

4.12

1.6

1.5

—

Corneal ulcer

874

7638

1.16

4.10

1.7

—

Internal derangement of knee

1765

16003

1.11

4.10

1.7

—

Haemorrhage, not elsewhere classified

579

1.59

4.10

1.7

1.6

—

Cardiomyopathy, other and unspecified

158

1135

1.41

4.09

1.5

1.6

—

Polyarteritis nodosa

145

2.30

4.07

1.7

—

Emotionally unstable personality disorder

1387

12572

1.14

4.06

2.1

1.7

—

Wegener granulomatosis

367

1.78

4.05

1.6

1.7

—

Guillain-Barre syndrome

429

1.72

4.05

1.6

1.7

—

Congenital malformations, deformations and chromosomal abnormalities

4709

42649

1.07

4.02

1.8

1.7

—

Alcohol-induced acute pancreatitis

590

1.58

4.02

1.8

1.7

—

Fracture of lumbar spine and pelvis

559

4706

1.20

4.01

1.6

1.7

—

Other hammer toe(s) (acquired)

206

1446

1.34

4.01

1.4

1.5

—

Certain conditions originating in the perinatal period

876

8760

0.86

4.00

1.8

—

Anti-inflammatory and antirheumatic products, non-steroids

2608

12111

1.09

3.98

1.8

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

124

1482

0.69

3.96

1.2

1.4

—

Colorectal cancer

175

2364

0.74

3.95

1.4

1.5

—

Sciatica+with lumbago

2186

19074

1.10

3.95

1.6

—

HSIL lesion of the cervix uteri, vagina or vulva

1914

17607

1.11

3.94

1.7

—

Mental and behabioural disorders of puerperum, not classified elsewhere, excluding more controls

130

944

1.54

3.93

1.8

1.7

—

Pleural effusion

217

1646

1.33

3.93

1.7

1.5

—

Non-seminoma of testis, excluding all cancers (controls excluding all cancers)

190

2.13

3.92

1.7

2.0

—

Toxic effect of ethanol

292

2338

1.30

3.91

1.9

1.8

—

Disorders of synovium and tendon

2396

23346

0.92

3.90

1.7

—

Coronary atherosclerosis

1088

6191

1.14

3.90

1.7

1.5

—

Uterine polyps

270

2119

1.29

3.89

1.5

1.6

—

Other and unspecified degenerative diseases of nervous system

193

2.02

3.88

1.2

1.4

—

Parkinson's disease, strict definition, excluding more controls

106

697

1.50

3.88

1.1

1.3

—

Kaposi sarcoma, excluding all cancers (controls excluding all cancers)

9.68

3.88

1.6

1.3

—

Diarrhoea and gastroenteritis of presumed infectious origin

4611

39594

1.07

3.87

1.8

1.7

—

Carpal tunnel syndrome

1680

16675

0.90

3.87

1.6

—

Rosacea

477

3994

1.22

3.87

1.7

—

Lichen planus, including avohilmo

409

3362

1.23

3.86

1.6

—

Pneumonia derived septicemia

149

1081

1.43

3.85

1.6

1.7

—

AV-block

258

1821

1.30

3.85

1.6

1.5

—

Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

106

713

1.50

3.85

1.4

1.5

—

Other systemic involvement of connective tissue (FG)

959

8403

1.14

3.83

1.5

1.7

—

Urethritis and urethral syndrome

112

775

1.51

3.81

2.0

1.7

—

Symptoms and signs concerning food and fluid intake

420

3475

1.23

3.80

1.7

—

Assault by blunt object

633

1.59

3.80

1.7

1.8

—

Other diseases of the respiratory system

348

2814

1.25

3.80

1.6

—

Other respiratory disorders and diseases

348

2814

1.25

3.80

1.6

—

Melanocytic naevi

1705

15568

1.11

3.80

1.8

1.7

—

Poisoning by narcotics and psychodysleptics [hallucinogens]

148

1094

1.46

3.79

2.0

1.8

—

Sequelae of external causes of morbidity and mortality

799

6968

1.16

3.79

1.8

1.7

—

Parkinson's disease, excluding more controls

118

792

1.46

3.79

1.1

1.4

—

Diseases of spleen

429

1.69

3.78

1.6

1.7

—

Melanocytic naevi

1705

15574

1.11

3.77

1.8

1.7

—

Infectious mononucleosis

1067

9599

1.15

3.76

1.8

—

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

315

2404

0.80

3.76

1.5

1.6

—

malignant neoplasm of female genital organs

154

2098

0.73

3.75

1.4

1.5

—

Other coagulation defects

390

3224

1.24

3.75

1.7

—

Propionic acid derivatives

2601

12111

1.09

3.74

1.8

—

Malignant neoplasm of respiratory system and intrathoracic organs

129

1669

0.71

3.74

1.2

1.4

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

1412

12766

1.12

3.73

1.6

—

L01XE Protein kinase inhibitors

100

672

1.51

3.73

1.3

1.5

—

Melanocytic naevi of trunk

621

5345

1.19

3.72

1.9

1.7

—

Colonic or urogenital fistula

958

8469

1.14

3.72

1.8

1.7

—

Encephalopathy

110

2.37

3.72

1.4

1.6

—

Hodgkin lymphoma, hilmo

158

1170

1.41

3.71

1.5

1.7

—

Isolated proteinuria with specified morphological lesion

287

1.85

3.70

2.5

1.6

—

Benign neoplasm: Colon

883

5925

1.15

3.70

1.5

—

HSIL lesion of the cervix uteri

1857

17126

1.11

3.69

1.7

—

Acute pharyngitis

1391

12551

1.12

3.69

1.9

1.7

—

Injuries to the shoulder and upper arm

3325

29754

0.93

3.69

1.7

—

Other and unspecified visual disturbances

377

3103

1.24

3.68

1.7

—

Lumbar disc prolapse

2372

20370

0.92

3.68

1.6

1.7

—

Familial hypercholesterolemia

234

1812

1.30

3.67

1.7

1.5

—

LSIL lesion of the cervix uteri, vagina or vulva

1163

10476

1.14

3.67

1.6

—

Disorder of lipoprotein metabolism, unspecified

186

1395

1.34

3.67

1.9

1.5

—

Other diseases of arteries and capillaries

235

1827

1.31

3.67

1.6

—

Other disorders of the musculoskeletal system and connective tissue

367

3004

1.24

3.66

1.5

1.6

—

Cryoglobulinemia

3.73

3.64

1.5

1.9

—

Unspecified privation

452

3789

1.21

3.64

1.8

1.7

—

Constipation

2868

22045

0.93

3.64

1.7

1.6

—

Other and unspecified mental retardation

604

0.50

3.63

1.7

1.8

—

Eosinophilic disease (BM)

411

1.69

3.61

1.5

1.7

—

Collagenous colitis

307

2476

1.26

3.61

1.7

1.6

—

Seminoma of testis, excluding all cancers (controls excluding all cancers)

201

1.99

3.60

2.0

1.8

—

Adverse effects, not elsewhere classified

1314

11897

1.12

3.60

1.7

—

Hypertrophic cardiomyopathy

655

1.52

3.59

1.5

1.6

—

Other gastritis (incl. Duodenitis)

548

4661

1.19

3.58

1.6

—

Colorectal cancer, excluding all cancers (controls excluding all cancers)

234

2894

0.78

3.57

1.4

1.5

—

Non-seminoma of testis

197

2.05

3.56

1.7

2.0

—

Other nonscarring hair loss

551

1.65

3.56

1.8

1.7

—

Benign neoplasm: Rectum

258

2034

1.28

3.54

1.6

1.5

—

Primary angle-closure glaucoma

385

1.66

3.54

1.4

—

Mental and behavioural disorders associated with the puerperium

130

963

1.50

3.53

1.8

1.7

—

Postprocedural disorders of nervous system

583

5040

1.19

3.53

1.8

1.7

—

Marginal zone B-cell lymphoma, excluding all cancers (controls excluding all cancers)

187

1.99

3.53

1.6

1.5

—

Hodgkin lymphoma

158

1181

1.40

3.52

1.5

1.7

—

Covid-19 suspected case

1697

15585

1.11

3.52

1.8

1.7

—

Discitis, unspecified

180

2.01

3.51

1.5

1.6

—

Any prescribed medicine buy

156

1.87

3.51

1.8

1.6

—

Behçet disease

131

2.41

3.50

1.6

—

Iron deficiency anaemia secondary to blood loss (chronic)

369

3035

1.23

3.50

1.9

1.6

—

Benign neoplasm: Skin of eyelid, including canthus

329

2675

1.24

3.49

1.6

—

Transepidermal elimination disorders

6.53

3.49

1.3

1.5

—

Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified

201

1549

1.33

3.49

1.6

—

Diseases of external ear

1342

12148

1.11

3.48

1.7

—

Melanocytic naevi of trunk

621

5376

1.18

3.48

1.9

1.7

—

Other CVD (FINNGEN)

249

1538

1.29

3.48

1.6

—

Diplopia

441

3701

1.21

3.47

1.6

1.7

—

Acute myeloid leukaemia and myelodysplastic syndromes

202

1.94

3.47

1.5

—

Haemorrhage from respiratory passages

866

7080

1.14

3.46

1.7

1.6

—

Hypertrichosis

159

2059

0.72

3.45

1.7

—

Localized swelling, mass and lump of skin and subcutaneous tissue

1192

10729

1.12

3.44

1.8

1.7

—

Specific personality disorders

2052

19023

1.10

3.42

2.0

1.7

—

Ischaemic heart disease, wide definition

1372

7745

1.11

3.42

1.6

1.5

—

Other symptoms and signs involving the urinary system

285

2291

1.26

3.41

1.9

1.6

—

D07AA Corticosteroids, weak (group I)

1259

11413

1.12

3.41

1.8

1.7

—

Peritonsillar abscess

1599

14659

1.11

3.40

1.8

1.7

—

Sequelae of cerebrovascular disease

482

3566

1.19

3.40

1.5

—

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

310

3660

0.81

3.39

1.4

1.5

—

Hordeolum and other deep inflammation of eyelid

290

2353

1.27

3.38

1.9

1.7

—

Acute tubulo-interstitial nephritis

3233

26922

1.07

3.38

1.7

—

Endometriosis of pelvic peritoneum

1194

10657

1.12

3.38

1.7

1.6

—

Mental and behavioural disorders of puerperium, not classified elsewhere

130

971

1.49

3.37

1.8

1.7

—

Other and unspecified disorders of skin and subcutaneous tissue

202

1562

1.32

3.37

1.7

1.6

—

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

883

0.61

3.37

1.3

1.4

—

Any reimbursement code in KELA

6296

32987

0.95

3.36

1.7

—

Asthma, including avohilmo

7839

43708

1.05

3.36

1.7

—

Subjective visual disturbances

1087

9762

1.13

3.35

1.6

1.7

—

Impetigo

319

2629

1.26

3.35

1.8

—

Other and unspecified disorders of psychological development

784

0.58

3.34

1.7

1.9

—

Osteopathies and chondropathies

2058

18033

1.09

3.34

1.7

—

Renal tubulo-interstitial diseases

4678

34043

1.06

3.31

1.9

1.7

—

Polycystic ovarian syndrome

886

8012

1.17

3.30

1.7

—

Temporomandibular joint disorders, including avohilmo

3736

35312

1.07

3.30

1.8

1.7

—

Other meningitis

643

1.53

3.30

1.4

1.7

—

Hydatidiform mole

111

799

1.49

3.30

1.9

1.6

—

Heart failure and coronary heart disease

320

1934

1.24

3.30

1.7

1.4

—

Functional dyspepsia

1098

9869

1.12

3.30

1.7

1.6

—

Speech and linguistic disorders, excluding more controls

746

7913

0.86

3.29

1.9

1.8

—

All influenza (not pneumonia)

698

6108

1.16

3.29

1.8

1.7

—

Heartburn

436

3680

1.20

3.29

1.7

—

Kaposi sarcoma

7.02

3.28

1.6

1.4

—

Behavioural disorders, excluding more controls

239

1931

1.32

3.27

2.2

1.8

—

Other noninfective gastroenteritis and colitis

1136

10231

1.12

3.27

1.7

—

Hyphaema and other vascular disorders of iris and ciliary body

421

1.63

3.26

1.7

—

Other specified/unspecified arthritis

1138

10255

1.12

3.26

1.6

1.7

—

Oligomenorrhoea

371

3130

1.25

3.26

1.8

1.7

—

Use of disulfiram, acamprosate or naltrexone

297

2416

1.25

3.25

1.8

1.7

—

Specific development disorders of speech and language

395

4482

0.82

3.25

1.8

1.9

—

Follicular cysts of skin and subcutaneous tissue

660

5754

1.16

3.25

1.7

—

Pneumococcal septicemia

141

1046

1.39

3.25

1.6

1.7

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

896

0.62

3.22

1.2

1.4

—

Complications of cardiac and vascular prosthetic devices, implants and grafts

222

1.85

3.22

2.4

1.6

—

Panic disorder

1577

14538

1.11

3.20

1.8

1.7

—

Car occupant injured in other and unspecified transport accidents

1412

12919

1.11

3.20

1.8

1.7

—

Vascular dementia

336

1.65

3.19

1.2

—

Seminoma of testis

210

1.90

3.19

2.0

1.8

—

Abnormal involuntary movements

482

4112

1.19

3.19

1.7

—

Pervasive developmental disorders excl. Autism + Asperger

764

0.58

3.19

2.2

1.8

—

Cervicalgia

739

6499

1.15

3.18

1.6

1.7

—

Overexertion and strenuous or repetitive movements

447

3796

1.20

3.18

1.8

1.7

—

Diseases of salivary glands

755

6654

1.15

3.17

1.7

1.6

—

Other disorders of iris and ciliary body

635

1.50

3.16

1.6

1.7

—

Injury of eye and orbit

750

6622

1.15

3.16

1.7

1.8

—

Dermatographic urticaria

435

3705

1.21

3.15

1.8

1.7

—

Convulsions, not elsewhere classified

1473

13317

1.10

3.15

1.8

1.7

—

Trochanteric bursitis

322

2645

1.23

3.15

1.6

1.5

—

Lichen planus

257

2060

1.26

3.15

1.6

—

Other disorders of gingiva or/and edentulous alveolar ridge

208

1636

1.30

3.13

1.9

1.6

—

Injury, poisoning and certain other consequences of external causes

4756

22651

1.06

3.13

1.7

—

Gastroduodenal ulcer

397

3315

1.20

3.12

1.7

1.5

—

Decubitus ulcer and pressure area

691

1.45

3.11

1.7

1.6

—

Carcinoma in situ of oral cavity, oesophagus and stomach

3.03

3.09

1.2

1.7

—

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

473

4055

1.19

3.08

1.7

1.6

—

Personality disorders

2296

21461

1.08

3.08

1.9

1.7

—

Blindness, monocular

127

2.14

3.07

1.6

—

Salpingitis and oophoritis

544

4695

1.17

3.07

1.6

—

Selective deficiency of immunoglobulin G [IgG] subclasses

261

1.83

3.07

1.7

—

Malignant neoplasm of ovary

756

0.60

3.04

1.5

—

Other abnormalities of plasma proteins

250

1.79

3.03

1.5

1.6

—

Malignant neoplasm of rectum

882

0.63

3.03

1.2

1.4

—

Abnormalities of heart beat

1713

15658

1.09

3.03

1.7

—

Other medical care

1256

11141

1.11

3.03

1.6

—

Benign neoplasm: Descending colon

620

1.47

3.02

1.5

1.4

—

Hirsutism in women

147

1882

0.73

3.02

1.7

—

Non-allergic asthma (mode), excluding more controls

868

7671

1.13

3.01

1.8

1.7

—

Other embolism and thrombosis

327

2705

1.22

3.01

1.7

1.6

—

Deforming dorsopathies

1345

12283

1.11

3.01

1.6

1.7

—

Papilloedema, unspecified

150

1147

1.38

3.01

1.6

1.8

—

Diseases caused by chlamydiae

314

1.71

3.00

1.9

1.6

—

Postzoster neuralgia

184

1.91

3.00

1.4

—

Arterial embolism and thrombosis

654

1.45

2.99

2.0

1.5

—

Episodal and paroxysmal disorders

8275

40839

1.04

2.99

1.7

—

Dementia in other diseases classified elsewhere

516

1.52

2.99

1.5

—

Diseases of the ear and mastoid process

8402

40956

1.04

2.98

1.7

—

Pain in thoracic spine

686

6042

1.15

2.98

1.7

—

Noninfective enteritis and colitis

2505

23426

1.08

2.98

1.7

—

Other disorders of white blood cells

184

1433

1.31

2.98

1.5

1.6

—

Cerebral amyloid angiopathy

3.54

2.97

1.1

1.5

—

Other prurigo

268

1.76

2.97

2.3

1.6

—

L02BX Other hormone antagonists and related agents

379

0.44

2.96

1.8

1.4

—

Alzheimer’s disease (Early onset)

227

1.78

2.96

1.1

1.2

—

Other epidermal thickening

153

1165

1.35

2.94

1.8

1.7

—

Varicose veins

1024

8603

0.90

2.94

1.4

1.5

—

Other and unspecified rosacea

295

2429

1.24

2.93

1.6

—

Non-allergic asthma (mode)

868

7686

1.13

2.93

1.8

1.7

—

L01XX Other antineoplastic agents

469

1.53

2.93

1.4

—

Suicide or other Intentional self-harm

1626

15017

1.10

2.93

1.9

1.7

—

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

1173

0.69

2.91

1.2

1.4

—

Benign neoplasm of male genital organs

200

1.84

2.90

1.6

—

Otitis externa

1046

9460

1.12

2.90

1.7

—

Feeding problems of newborn

295

1.83

2.90

1.7

1.8

—

Bell's palsy

440

3761

1.19

2.89

1.8

1.7

—

Other/unspecified reactive arthropathies

291

2402

1.24

2.89

1.7

—

Use of galantamine

312

1.65

2.89

1.0

1.2

—

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

1309

12007

1.11

2.88

1.9

1.7

—

Disorders of vestibular function (Vertigo)

1189

10725

1.11

2.88

1.6

—

Carcinoma in situ of oral cavity, oesophagus and stomach

2.90

2.88

1.2

1.7

—

Use of fingolimod

739

0.59

2.87

1.4

1.7

—

Spermatocele

108

777

1.40

2.87

1.5

1.8

—

Benign paroxysmal vertigo

696

6139

1.14

2.86

1.6

—

Filariasis

5.74

2.86

1.3

1.5

—

Specific developmental disorder of motor function

1080

0.67

2.85

2.1

1.9

—

Behavioural disorders

239

1967

1.29

2.85

2.2

1.8

—

Abdominal aortic aneurysm (AAA)

580

1.46

2.85

1.2

1.3

—

Ulcer of vagina/vulva

189

1506

1.32

2.85

1.8

1.7

—

Primary open-angle glaucoma, strict

250

2015

1.24

2.84

1.4

—

Bleeding

2357

18345

0.93

2.83

1.7

1.6

—

Congenital hydrocephalus

210

0.35

2.83

3.0

1.8

—

Diseases of tongue

201

1593

1.28

2.83

1.8

1.6

—

Biomechanical lesions, not elsewhere classified

145

1102

1.34

2.82

1.4

1.6

—

Adenocarcinoma and papilloma adenocarcinoma of rectum

854

0.64

2.81

1.2

1.4

—

Cerebral palsy

1031

0.66

2.80

1.6

1.8

—

Injuries to the neck

1534

14170

1.10

2.80

1.8

1.7

—

L02BB Anti-androgens

568

0.56

2.80

1.4

1.3

—

Acute myeloid leukaemia

146

2.00

2.79

1.6

—

2.75

2.79

1.1

1.6

—

Lichen simplex chronicus

701

1.43

2.79

1.8

1.5

—

Oral leukoplakia and related diseases, including avohilmo

181

1416

1.29

2.78

1.8

1.6

—

Gingival hyperplasia

130

978

1.37

2.77

2.1

1.6

—

Motor disorders, excluding more controls

1044

0.67

2.76

2.1

1.8

—

Otitis externa, unspecified

568

4979

1.16

2.76

1.7

—

Meniscus derangement

1390

10381

0.91

2.76

1.5

1.7

—

Sequelae of other external causes

185

1459

1.29

2.74

1.7

1.6

—

Diseases of the digestive system

1536

14124

1.09

2.74

1.8

1.7

—

Visual impairment including blindness (binocular or monocular)

190

1502

1.29

2.72

1.7

1.6

—

Other systemic involvement of connective tissue

981

8865

1.12

2.72

1.5

1.6

—

Alcoholic gastritis

161

1.91

2.72

1.5

—

Vascular disorders of the intestines

567

1.46

2.72

1.9

1.5

—

Benign neoplasm of colon, rectum, anus and anal canal

1103

7135

1.11

2.72

1.6

1.5

—

Idiopathic thrombocytopenic purpura

141

1080

1.35

2.71

1.8

1.7

—

Other bacterial diseases

3876

25443

1.06

2.70

1.8

1.7

—

Diseases of liver

919

8274

1.12

2.69

1.7

1.6

—

Other and unspecified follicular disorders

188

1496

1.29

2.69

1.9

1.7

—

Transient global amnesia

102

736

1.40

2.68

1.4

—

Benign neoplasm: Adrenal gland

125

934

1.35

2.67

1.5

—

Crowding of teeth, including avohilmo

959

8668

0.89

2.67

1.8

—

Carcinoma in situ of breast, intraductal

1068

0.69

2.67

1.6

1.5

—

Nonischemic cardiomyopathy

117

867

1.37

2.66

1.4

1.6

—

Other specified/unspecified bacterial intestinal infections

188

1490

1.28

2.66

1.6

—

DVT of lower extremities

406

3465

1.18

2.66

1.6

—

Other diseases caused by chlamydiae

341

1.63

2.64

2.1

1.7

—

Family history of other conditions

116

880

1.42

2.64

1.9

1.7

—

LSIL lesion of the cervix uteri

1051

9615

1.12

2.64

1.7

—

Pyogenic arthritis

174

1366

1.29

2.63

1.7

—

Acute hepatitis B

123

2.12

2.62

3.3

1.7

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

189

1996

0.79

2.62

1.3

1.5

—

Hypokalaemia

262

2154

1.23

2.62

1.7

1.6

—

Aortic valve malfunction, age under 60 years

257

2112

1.23

2.61

1.8

1.7

—

Other and unspecified nonscarring hair loss

449

1.61

2.61

2.0

1.7

—

Eosinophilia

447

1.54

2.60

1.5

1.7

—

Sequelae with surgical and medical care as external cause

535

4675

1.15

2.60

1.8

1.6

—

Presbyopia

121

905

1.35

2.59

1.3

1.5

—

Unspecified/other endometriosis

936

8526

1.12

2.58

1.7

1.6

—

Laparoscopic right hemicolectomy

489

0.55

2.58

1.7

1.4

—

Benign neoplasm: Descending colon

641

1.42

2.58

1.5

1.4

—

Benign neoplasm: Small intestine

403

1.54

2.57

1.5

—

Pyogenic granuloma

702

1.43

2.57

1.6

1.7

—

Unspecified maternal hypertension

126

978

1.41

2.57

1.9

1.6

—

Hypertension, essential

2478

15062

0.94

2.57

1.7

1.6

—

Malignant neoplasm of pancreas

514

0.56

2.56

1.3

1.5

—

Thyrotoxicosis, other and/or unspecified

911

8241

1.12

2.56

1.6

1.7

—

Motor disorders

1075

0.68

2.56

2.1

1.9

—

Combinations of oral blood glucose lowering drugs

321

3815

0.84

2.56

1.5

—

Benign neoplasm of other and ill-defined parts of digestive system

339

2860

1.19

2.56

1.6

—

Acquired pure red cell aplasia [erythroblastopenia]

110

2.16

2.56

1.8

1.7

—

Conduct disorder

237

1972

1.27

2.56

2.3

1.9

—

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

713

0.63

2.55

1.4

—

Other and unspecified mood [affective] disorders

734

6613

1.14

2.55

1.9

1.7

—

Restrictive cardiomyopathy

3.00

2.55

1.2

1.9

—

Exposure to other specified factors

4602

41292

1.05

2.54

1.8

1.7

—

Superficial injuries involving multiple body regions

156

1227

1.32

2.54

2.2

1.7

—

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

339

2904

1.22

2.53

1.8

—

Paralytic strabismus

181

1437

1.28

2.53

1.5

1.6

—

Amiodarone users

121

907

1.35

2.53

1.3

1.4

—

Type 2 diabetes, wide definition

1758

12340

0.93

2.53

1.8

1.6

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

868

0.66

2.53

1.2

1.4

—

Postmenopausal atrophic vaginitis

333

1678

1.20

2.52

1.3

1.4

—

Other noninfective disorders of lymphatic vessels and lymph nodes

105

775

1.39

2.52

1.7

1.6

—

Disorders of lipoprotein metabolism and other lipidaemias

1881

10992

1.08

2.52

1.7

1.6

—

Other joint disorders

7120

39298

0.96

2.50

1.7

—

Retinal breaks without detachment

272

2254

1.22

2.50

1.7

1.5

—

Secondary polycythaemia

359

1.57

2.50

1.7

—

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

1063

0.70

2.49

1.5

1.6

—

Carcinoma in situ of breast, intraductal

1052

0.70

2.48

1.6

1.5

—

Tongue abnormality

149

1158

1.31

2.48

1.9

1.6

—

Other general symptoms and signs

276

2284

1.22

2.48

1.7

—

Erythema intertrigo

475

1.49

2.47

1.8

1.6

—

Acute myeloid leukaemia, excluding all cancers (controls excluding all cancers)

153

1.90

2.46

1.6

1.5

—

Acute myeloid leukaemia, helper endpoint

153

1.90

2.46

1.6

1.5

—

Endometriosis of rectovaginal septum and vagina

392

3377

1.18

2.46

1.6

—

Measles

228

1.73

2.46

1.8

1.6

—

Aspergillosis

125

2.01

2.44

2.0

1.6

—

Other diseases of blood and blood-forming organs

164

1293

1.29

2.43

1.7

—

Adenocarcinoma and Papillary adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

2.18

2.43

2.5

1.5

—

Viral pneumonia (unknown virus, not influenza)

330

2809

1.20

2.43

1.8

1.7

—

Dissocial personality disorder

521

1.48

2.43

1.5

1.9

—

Atopic dermatitis, strict definition with reimbursement

3112

28709

1.06

2.43

1.8

1.7

—

Falls/tendency to fall

8335

40383

1.04

2.40

1.7

—

Other or ill-defined heart diseases

165

1305

1.28

2.40

2.1

1.7

—

Chronic laryngitis and laryngotracheitis

367

3141

1.18

2.39

1.7

1.6

—

Cyst of kidney

103

762

1.37

2.38

1.8

1.5

—

Disease of hard tissues of teeth, NOS

384

1.57

2.38

1.7

1.6

—

Focal brain injury

178

1421

1.27

2.38

1.7

—

Disorders of oesophagus in diseases classified elsewhere

276

1.63

2.37

1.3

1.6

—

Injuries involving multiple body regions

202

1649

1.26

2.37

2.1

1.7

—

Vascular dementia (subcortical)

111

2.00

2.37

1.1

1.2

—

Other inflammatory liver diseases

218

1785

1.24

2.36

1.7

1.6

—

Cervical disc disorders

782

7033

1.12

2.36

1.5

1.6

—

Cardiac arrest

114

737

1.35

2.36

1.6

1.5

—

Torsion of testis

650

1.41

2.36

2.1

2.0

—

Vascular diseases of the intestine

355

1.54

2.35

2.1

1.6

—

Psoriasis

984

8970

1.10

2.34

1.6

1.7

—

Benign neoplasm of urinary organs

612

1.41

2.34

1.5

—

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

841

0.67

2.34

1.2

1.4

—

Hydronephrosis

330

2808

1.19

2.34

2.0

1.6

—

Other diseases of jaws

319

2716

1.20

2.33

1.7

1.6

—

Abnormal results of function studies

327

2787

1.19

2.33

1.7

—

Cardiomyopathy, Hypertrophic obstructive

286

1.61

2.32

1.3

1.5

—

External causes of morbidity and mortality

5563

26796

1.05

2.31

1.7

—

Allergic asthma (mode), excluding more controls

2131

19707

1.07

2.30

1.7

—

Background retinopathy and retinal vascular changes

375

1.53

2.30

2.7

1.6

—

Exposure to other and unspecified animate mechanical forces

211

1745

1.26

2.30

1.9

1.8

—

Carcinoma in situ of lip, oral cavity and pharynx

3.34

2.30

1.3

1.9

—

Other noninflammatory disorders of vagina

420

3660

1.17

2.30

1.7

1.6

—

Monoarthritis, not elsewhere classified

167

1335

1.28

2.29

1.6

1.7

—

Benign neoplasm: Transverse colon

132

1019

1.31

2.28

1.5

—

Other female pelvic inflammatory diseases

751

6776

1.12

2.28

1.7

1.6

—

severe traumatic brain injury, does not include concussion

456

3978

1.15

2.28

1.6

1.7

—

Examination and encounter for administrative purposes

126

971

1.32

2.28

1.7

1.6

—

Misadventures to patients during surgical and medical care

471

4130

1.15

2.26

1.7

1.6

—

Other and unspecified myopathies

178

1430

1.26

2.26

1.7

1.6

—

Fall on and from stairs and steps

988

9032

1.10

2.26

1.9

1.7

—

Chronic myeloproliferative disease

150

1.85

2.25

1.4

1.5

—

Vascular syndromes of brain in cerebrovascular disorders

424

1.48

2.25

1.3

1.4

—

ILD and respiratory illness in diseases classified elsewhere

2.36

2.25

1.1

1.6

—

Insulin, fast-acting (human)

785

8651

0.90

2.24

1.9

1.7

—

Suppurative and unspecified otitis media

3888

33031

1.05

2.23

1.8

1.7

—

Iridocyclitis in diseases classified elsewhere

530

1.45

2.22

1.4

1.7

—

Acute alcohol intoxication ICD-9

352

1.53

2.22

1.5

1.4

—

Aneurysms, operations, SAH

295

2494

1.19

2.22

1.6

—

Psoriasis (vulgaris), strict definition

115

881

1.34

2.22

1.6

1.7

—

Gastro-oesophageal reflux disease

2490

20837

1.06

2.22

1.7

1.6

—

Other and unspecified psoriasis

177

1427

1.26

2.22

1.6

—

Cerebral aneurysm, nonruptured

178

1434

1.25

2.21

1.6

—

Dislocation, sprain and strain of joints and ligaments at neck level

1181

10931

1.10

2.21

1.8

1.7

—

Cerebrovascular diseases

1448

9611

1.08

2.21

1.5

1.6

—

Cough

1788

16060

1.07

2.21

1.7

—

Assault by hanging, strangulation and suffocation

233

1.90

2.20

2.3

1.8

—

Polyarteritis nodosa and related conditions

448

1.49

2.20

1.6

1.7

—

Allergic asthma (mode)

2131

19743

1.07

2.20

1.7

—

Other and unspecified urticaria

1191

11012

1.09

2.20

1.6

1.7

—

Other and unspecified epidermal thickening

113

867

1.34

2.19

1.9

1.7

—

Meningitis

204

1678

1.24

2.18

1.6

1.7

—

Malignant neoplasm of other and unspecified female genital organs, excluding all cancers (controls excluding all cancers)

253

0.43

2.17

1.0

1.4

—

Dissection of aorta

258

1.61

2.17

1.2

1.5

—

Other noninflammatory disorders of uterus, except cervix

332

2648

0.85

2.17

1.6

1.5

—

Benign neoplasm: Small intestine

420

1.47

2.16

1.5

—

Inflammatory disorders of male genital organs, not elsewhere classified

167

1.78

2.16

2.2

1.8

—

Infective dermatitis

399

3473

1.16

2.16

1.8

1.7

—

Degenerative macular diseases

149

1178

1.27

2.15

1.5

1.4

—

Other arterial embolism and thrombosis

331

1.54

2.15

2.5

1.6

—

Disorders of orbit

167

1347

1.27

2.15

1.6

1.7

—

Other erythematous conditions

111

850

1.34

2.15

1.7

1.6

—

Problems related to social environment

163

1317

1.28

2.14

1.7

—

Early lumbar disc prolapse operation

586

6532

0.88

2.14

1.7

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

146

1.85

2.14

1.3

1.8

—

Benign neoplasm of male genital organs

221

1.66

2.13

1.6

—

Serous carcinoma of ovary

433

0.57

2.12

1.2

1.4

—

Alzheimer’s disease (Atypical or mixed)

354

1.50

2.12

1.1

1.2

—

Carcinoma in situ of oral cavity

3.75

2.11

1.4

2.0

—

Carcinoma in situ of oral cavity

3.75

2.11

1.4

2.1

—

Tuberculosis, IBD comorbidity

103

778

1.34

2.11

1.6

1.4

—

Benign neoplasm: Ascending colon

162

1298

1.26

2.10

1.5

—

Malignant neoplasm of gallbladder, excluding all cancers (controls excluding all cancers)

0.00

2.10

0.0

1.2

—

Other and unspecified aplastic anaemias

296

1.59

2.09

1.7

1.6

—

Other keratitis

587

5261

1.13

2.09

1.9

1.7

—

Third [oculomotor] nerve palsy

278

1.59

2.09

1.3

1.7

—

Benign neoplasm: Caecum

125

971

1.30

2.09

1.5

1.4

—

Other salmonella infections

128

1003

1.30

2.09

1.5

1.6

—

Diseases of arteries, arterioles and capillaries

1391

9628

1.08

2.09

1.7

1.6

—

Malignant neoplasm of corpus uteri, excluding all cancers (controls excluding all cancers)

785

0.68

2.09

1.2

1.4

—

Myocardial infarction, without ST-elevation

414

3328

1.15

2.08

1.5

1.4

—

Benign neoplasm of other and ill-defined parts of digestive system

339

2918

1.17

2.08

1.6

—

Abnormal findings on examination of blood, without diagnosis

1256

10880

1.08

2.08

1.6

—

Other shoulder lesions

400

3498

1.16

2.07

1.7

—

Unspecified contracted kidney

134

1.90

2.06

2.0

1.7

—

Other/unspecified crystal arthropathies

2.31

2.06

1.1

1.5

—

Nonhereditary hypogammaglobulinemia

314

1.57

2.06

1.8

1.7

—

Injuries to unspecified part of trunk, limb or body region

419

3679

1.16

2.06

1.9

1.7

—

Testicular dysfunction, other/unspecified

2.21

2.05

1.6

1.9

—

Malignant neoplasm of oesophagus

175

0.40

2.05

1.1

1.3

—

Acute lymphadenitis

379

3317

1.17

2.05

1.8

1.7

—

Non-small cell lung cancer

1211

0.75

2.05

1.2

1.4

—

Gonarthrosis

1267

7857

0.92

2.04

1.4

1.6

—

Benign neoplasm: Adrenal gland

125

976

1.29

2.04

1.5

—

Other aneurysm

534

1.40

2.04

2.0

1.5

—

Diseases of inner ear

1407

12819

1.08

2.04

1.6

—

Non-small cell lung cancer, adenocarcinoma, helper endpoint

467

0.59

2.04

1.1

1.3

—

Non-small cell lung cancer, adenocarcinoma

467

0.59

2.04

1.1

1.3

—

Other specified and unspecified personality disorders

618

5574

1.13

2.04

1.9

1.7

—

Transient ischemic attack

779

5849

1.11

2.03

1.5

—

Hypersplenism

106

2.03

1.5

1.6

—

Ischaemic Stroke, excluding all haemorrhages

841

5779

1.10

2.03

1.4

1.5

—

131

1027

1.29

2.02

1.7

1.6

—

Crystal arthropathies, rheuma endpoint

133

1.84

2.02

1.3

1.5

—

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

149

1.81

2.02

1.3

1.8

—

Benign neoplasm: Anus and anal canal

411

1.46

2.01

1.9

1.6

—

Benign neoplasm of mouth and pharynx

288

2459

1.18

2.01

1.7

1.6

—

Ovarian dysfunction

1022

9511

1.11

2.00

1.7

—

Ulcer of oesophagus

105

803

1.32

2.00

1.3

1.5

—

Carcinoma in situ of lip, oral cavity and pharynx

2.92

2.00

1.3

1.8

—

Benign neoplasm of urinary organs

631

1.37

1.99

1.5

—

Injury of unspecified body region

306

2634

1.18

1.99

1.9

1.7

—

Hallux rigidus

179

1460

1.23

1.99

1.4

1.5

—

Androgenic alopecia

352

1.54

1.99

1.6

—

Other diseases of the digestive system

735

6663

1.11

1.98

1.8

1.6

—

Viral meningitis

237

2009

1.22

1.98

1.8

1.7

—

Haemolytic-uraemic syndrome

148

1.95

1.97

2.0

1.8

—

Early onset COPD

403

3528

1.15

1.97

1.6

—

719

1.39

1.97

2.0

1.8

—

Mononeuritis multiplex

2.48

1.96

1.8

1.6

—

Enteropathic arthropathies

110

857

1.32

1.96

1.7

—

Carcinoma in situ of oropharynx, excluding all cancers

3.50

1.95

1.1

1.5

—

Carcinoma in situ of oral cavity and pharynx

3.50

1.95

1.1

1.6

—

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

1133

0.75

1.95

1.2

1.4

—

Maternal care for (suspected) damage to fetus from alcohol

350

1.66

1.95

1.7

—

Disorders of speech understanding and production

229

2642

0.83

1.95

1.8

1.9

—

Colectomy operation

233

2765

0.84

1.94

1.6

—

In situ neoplasms

1352

12608

1.08

1.94

1.7

1.6

—

Serous carcinoma of ovary, excluding all cancers (controls excluding all cancers)

421

0.59

1.93

1.2

1.5

—

Other acute viral hepatitis

479

1.44

1.93

2.0

1.8

—

Benign neoplasm: Duodenum

259

1.57

1.93

1.5

—

Other endophthalmitis

2.08

1.92

1.5

1.8

—

Kela reimbursement Agammaglobulinemia (D80-84)

296

1.57

1.92

1.7

—

Thyrotoxicosis

1038

9593

1.09

1.91

1.6

—

Open wound of hip and thigh

180

1491

1.24

1.91

2.1

1.8

—

Other follicular disorders

421

3729

1.15

1.91

1.8

1.7

—

Other complications of surgical and medical care, not elsewhere classified

384

3371

1.15

1.91

1.7

—

Obesity, other/unspecified

1985

18772

1.07

1.90

1.8

1.7

—

Venous complications and haemorrhoids in the puerperium

447

1.46

1.90

1.9

1.7

—

Cervicobrachial syndrome

804

7347

1.10

1.90

1.5

1.6

—

Urethral stricture

662

1.34

1.89

2.3

1.6

—

Other disorders of eye and adnexa

691

6283

1.11

1.89

1.6

1.7

—

Malignant neoplasm of colon

113

1442

0.78

1.89

1.4

—

Use of teriflunomide

576

0.64

1.89

1.4

1.7

—

Mouth breathing

1272

11833

1.08

1.88

1.7

—

Retention of urine

687

5257

1.11

1.88

1.7

1.6

—

Benign neoplasm: Anus and anal canal

417

1.44

1.88

1.9

1.6

—

Infective bursitis

434

1.43

1.88

1.6

—

Sleep apnoea

2779

19789

0.95

1.88

1.7

1.6

—

Vitiligo

448

1.45

1.88

1.5

1.7

—

Malaria

170

1.76

1.87

1.8

1.7

—

Other disorders of conjunctiva

281

2408

1.18

1.87

1.8

1.6

—

Hypopituitarism

281

2416

1.18

1.87

1.6

1.8

—

Carcinoma in situ of skin of other and unspecified parts of face

424

1.42

1.87

1.3

1.2

—

Childhood asthma (age<16), excluding more controls

2326

17607

1.07

1.86

1.8

—

Motor neuron disease

122

1.83

1.86

1.4

—

Pain and other conditions associated with female genital organs and menstrual cycle

2200

20076

1.06

1.85

1.7

—

Unspecified urinary incontinence

241

2045

1.19

1.85

1.6

—

Complications of other internal prosthetic devices, implants and grafts

728

1.33

1.85

1.7

1.6

—

Benign neoplasm: Duodenum

262

1.55

1.85

1.5

1.4

—

Adenocarcinoma and Papillary adenocarcinoma of kidney

101

1.93

1.84

2.5

1.6

—

Childhood asthma (age<16)

2326

17620

1.07

1.84

1.8

—

Melanocytic naevi, other sites/unspecified

370

3254

1.16

1.84

1.9

1.7

—

Superficial injury of hip and thigh

515

4609

1.13

1.84

1.7

—

Other and unspecified drugs and medicaments

323

2811

1.17

1.84

1.8

1.7

—

Injury of muscle and tendon at neck level

114

2.10

1.84

1.3

1.6

—

Nocardiosis

3.81

1.84

1.2

1.9

—

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

751

1.31

1.83

1.4

1.3

—

Other disorders of pigmentation

128

1022

1.27

1.83

1.6

1.7

—

Exposure to unspecified factor

6017

45217

1.04

1.82

1.8

1.7

—

Other and unspecified tonsillitis

3658

29852

1.05

1.82

1.9

1.7

—

Ocular pain

427

3797

1.14

1.81

1.6

1.7

—

Achilles tendinitis

259

2214

1.18

1.81

1.8

1.6

—

Speech disturbances, not elsewhere classified

193

1608

1.21

1.81

1.5

1.6

—

Insulin medication

2159

19464

0.94

1.81

1.8

1.7

—

Open wound of lower leg

626

5676

1.11

1.81

1.7

—

Dislocation of lens

146

1.75

1.80

1.9

1.6

—

Other disorders of optic [2nd] nerve and visual pathways

270

2325

1.18

1.80

1.6

1.7

—

Melanocytic naevi, other sites/unspecified

370

3260

1.15

1.80

1.9

1.7

—

conjunctival haemorrhage

132

1057

1.26

1.80

1.8

1.5

—

Other melanin hyperpigmentation

256

1.55

1.80

1.4

1.5

—

Benign neoplasm of mouth and pharynx

288

2485

1.17

1.80

1.7

1.6

—

Benign neoplasm of eye and adnexa

237

2013

1.19

1.79

1.7

1.6

—

Non-rheumatic valve diseases

982

6606

1.09

1.79

1.7

1.6

—

Other parasitologically confirmed or unspecified malaria

2.14

1.79

1.6

1.9

—

Certolizumab pegol

167

1400

1.26

1.79

1.7

—

Congenital malformations and deformations of the musculoskeletal system

608

6639

0.89

1.79

1.8

—

Other crystal arthropathies

139

1.75

1.78

1.3

1.4

—

Myocardial infarction, with ST-elevation

186

1543

1.21

1.78

1.4

1.5

—

Motor neuron disease (with DMD)

139

1.75

1.77

1.5

1.4

—

Lichen planopilaris

2.45

1.77

2.5

1.7

—

Abscess of anal and rectal regions

337

2950

1.16

1.77

1.8

1.7

—

Vasculitis limited to skin, not elsewhere classified

500

1.39

1.77

1.7

1.6

—

Anxious personality disorder

114

1411

0.77

1.76

2.1

1.8

—

Sequelae of injuries of head

196

1645

1.21

1.76

1.8

1.7

—

Tuberculosis of other organs

225

1.58

1.76

1.5

1.4

—

Stroke, excluding SAH

943

6452

1.09

1.76

1.4

1.5

—

Generalized anxiety disorder

1604

15168

1.07

1.75

1.9

1.7

—

Allergic contact dermatitis

767

7041

1.10

1.75

1.7

—

Sequelae of inflammatory diseases of the central nervous system

2.09

1.75

1.5

1.7

—

Adenocarcinoma and ductal carcinoma of pancreas

244

0.49

1.75

1.5

1.3

—

Tuberculosis, wide

105

820

1.29

1.74

1.6

1.4

—

Inguinal hernia, bilateral

169

1394

1.22

1.74

1.5

1.6

—

Weight loss

338

2963

1.15

1.74

1.7

—

Left ventricular outflow tract obstruction (LVOTO), broad definition

293

2540

1.17

1.74

1.9

1.7

—

Other secondary coxarthrosis

509

1.38

1.74

1.5

1.6

—

Persistent mood disorders

971

8998

1.09

1.73

1.8

1.7

—

Lung cancer and mesothelioma

127

1353

0.80

1.73

1.2

1.4

—

COPD-related respiratory insufficiency

125

998

1.26

1.73

1.8

1.4

—

Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

243

0.49

1.73

1.5

1.3

—

Other and unspecified erythematous conditions

764

1.31

1.73

1.7

—

Ventral hernia

522

4691

1.12

1.72

1.7

1.6

—

Emphysema

690

1.31

1.72

1.3

1.4

—

Injury of muscle and tendon at shoulder and upper arm level

649

5896

1.10

1.72

1.5

1.6

—

Nail disorders

349

3072

1.15

1.72

1.8

1.7

—

Postviral fatigue syndrome

621

1.40

1.72

1.6

1.7

—

Thrombotic microangiopathy

190

1.67

1.71

2.1

1.9

—

Other and unspecified nail disorders

600

1.35

1.71

1.5

1.6

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

481

0.64

1.71

1.3

1.4

—

Fasciculation

465

1.42

1.71

1.7

—

Chronic crepitant synovitis/bursitis of hand and wrist/periarthritis of wrist

310

1.49

1.70

1.5

1.6

—

Benign neoplasm: Prostate

2.45

1.70

1.5

1.3

—

Other neurotic disorders

125

1004

1.26

1.70

1.5

1.6

—

Other dorsopathies, not elsewhere classified

7696

39497

1.03

1.70

1.7

—

Other, unspecified and serous retinal detachments

426

1.41

1.70

1.5

1.6

—

Familial hypercholesterolemia, with ischemic heart disease

665

1.32

1.69

1.7

1.4

—

Oral leukoplakia and related diseases

693

1.31

1.69

1.7

1.5

—

Ascorbic acid deficiency

4.08

1.69

1.8

—

Other sleep disorders

450

4026

1.13

1.69

1.9

1.7

—

Corns and callosities

176

1467

1.21

1.68

1.8

1.6

—

Tuberculosis of other organs, strict

252

1.53

1.68

1.5

1.4

—

Low back pain

4505

35908

0.96

1.68

1.7

—

Asthma and allergy

1326

12323

1.08

1.67

1.8

1.7

—

Congenital malformations of uterus and cervix

249

2178

1.21

1.67

1.8

1.7

—

Ulcerative ileocolitis

150

1810

0.81

1.67

1.7

—

Polycythaemia vera

301

1.48

1.67

1.4

—

Valvular heart disease excluding rheumatic fever

996

6735

1.08

1.67

1.7

1.6

—

Striking against or struck by other objects

1986

18857

1.06

1.67

1.7

1.8

—

Cholesteatoma of middle ear

1065

0.76

1.67

1.6

—

Cyst of Bartholin Gland

226

1940

1.19

1.66

1.7

1.6

—

Other specified/unspecified soft tissue disorders

133

1079

1.25

1.66

1.5

—

Later onset COPD

150

1436

0.82

1.66

1.3

—

Use of antiglaucoma preparations and miotics

108

853

1.28

1.66

1.4

1.5

—

Relapsing polychondritis

2.17

1.66

1.4

1.7

—

TMD related pain

240

2075

1.19

1.66

1.6

1.7

—

Other diseases of pancreas

129

1042

1.25

1.65

1.8

1.5

—

Oral lichen ruber planus wide, hypothyreosis or thyroxin

740

1.30

1.65

1.5

—

Asthma and allergy, excluding more controls

1326

12330

1.08

1.65

1.8

1.7

—

Adult respiratory distress syndrome

174

1.65

2.0

1.6

—

Amenorrhoea

908

8474

1.10

1.65

1.8

1.7

—

Persistent delusional disorders

206

1745

1.19

1.65

1.7

—

Other diseases of stomach and duodenum

119

953

1.26

1.65

1.7

1.5

—

Miliary tuberculosis

3.78

1.65

1.0

1.8

—

Superficial injury of lower leg

1434

13506

1.07

1.64

1.8

1.7

—

Inguinal or femoral hernia, bilateral

172

1431

1.21

1.64

1.5

1.6

—

Helminthiases

623

1.34

1.64

1.8

1.7

—

Hypermobility syndrome

387

4319

0.87

1.64

1.6

1.7

—

Congenital malformations of the nervous system

123

1499

0.79

1.64

1.8

—

Biliary cirrhosis, NAS

2.63

1.64

2.0

1.5

—

Complications following abortion and ectopic and molar pregnancy

672

1.32

1.64

1.6

1.5

—

Arthropathy in Crohn disease

435

1.42

1.63

1.8

1.7

—

Diseases of the myoneural junction and muscle

287

2496

1.16

1.63

1.6

1.7

—

Benign neoplasm of other and unspecified endocrine glands

347

3059

1.14

1.63

1.6

—

Sub-endpoint used in defining T1D endpoints

1358

14203

0.93

1.63

1.9

1.7

—

Acquired absence of limb

144

1.72

1.62

2.4

1.7

—

Type 1 diabetes, wide definition, subgroup 2

275

0.54

1.62

1.5

1.7

—

Injuries to the elbow and forearm

3748

35140

0.96

1.62

1.7

—

GI-bleeding

732

6711

1.10

1.62

1.7

1.6

—

Medicines for HER+ breast cancer

625

6682

0.91

1.62

1.6

1.5

—

Impingement syndrome of shoulder

450

4027

1.12

1.61

1.4

1.5

—

Kela-code for severe mental illness

1927

20277

0.94

1.61

1.8

1.7

—

Car occupant injured in noncollision transport accident

253

2201

1.18

1.61

1.8

—

Cholecystectomy

2124

19736

0.95

1.61

1.6

—

Angina pectoris

797

4941

1.09

1.60

1.5

—

Other vitreous opacities

104

825

1.28

1.60

1.8

1.6

—

Infection due to other mycobacteria

199

1.59

1.60

1.4

1.6

—

Noninfectious colitis NAS

597

5440

1.11

1.60

1.8

1.7

—

Fracture at wrist and hand level

1799

17050

1.06

1.60

1.8

—

Other and unspecified glaucoma

637

1.31

1.60

1.6

1.5

—

Other and unspecified vasculitis limited to skin

458

1.38

1.59

1.8

1.7

—

Visual field defects

213

1816

1.18

1.59

1.5

1.6

—

Psychotic depression

365

3247

1.14

1.59

1.8

1.6

—

Campylobacter enteritis

108

865

1.28

1.58

1.9

1.7

—

Intermittent hydrarthrosis

2.33

1.58

1.5

1.9

—

Other and unspecified cicatricial alopecia

2.25

1.58

1.5

1.6

—

Paralytic ileus and intestinal obstruction

470

4220

1.12

1.58

1.6

—

Other and unspecified mononeuropathies, also in other diseases

562

1.34

1.58

1.8

1.6

—

Malignant neoplasm of rectosigmoid junction, excluding all cancers (controls excluding all cancers)

234

0.51

1.57

1.6

1.4

—

Cicatricial alopecia [scarring hair loss]

170

1.65

1.56

1.9

1.6

—

Other specific arthropathies, wide

502

0.66

1.56

1.2

1.6

—

Varicella [chickenpox]

232

2004

1.18

1.55

1.8

—

Opioids

7411

39942

0.97

1.55

1.8

1.7

—

Symptoms and signs involving the urinary system

2742

20288

1.05

1.55

1.8

1.6

—

Coxibs

2052

11481

0.95

1.55

1.7

1.8

—

Tubulo-interstitial nephritis, not specified as acute or chronic

240

2074

1.17

1.54

1.6

—

Asthma, hospital admissions , main diagnosis only

5088

44171

1.03

1.54

1.7

—

Intracranial and intraspinal abscess and granuloma

194

1.59

1.54

1.4

1.6

—

Other diseases of intestine

204

1736

1.18

1.53

1.8

1.5

—

Disorders of adult personality and behaviour

2438

23363

1.05

1.53

2.0

1.7

—

Malignant neoplasm of cervix uteri, excluding all cancers (controls excluding all cancers)

1010

0.76

1.53

1.5

1.6

—

Other abortion

558

1.37

1.53

1.7

1.6

—

Carcinoma in situ of cervix uteri

1002

9405

1.09

1.53

1.7

—

Left side

0.00

1.53

0.0

1.4

—

Other degenerative diseases of the basal ganglia

108

1.79

1.52

1.1

1.2

—

Total colectomy

112

1379

0.80

1.52

1.7

—

Total colectomy operation

112

1379

0.80

1.52

1.7

—

Use of rasagiline

205

0.48

1.52

1.2

1.4

—

Palindromic rheumatism

216

0.49

1.52

1.3

1.6

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

364

3242

1.14

1.52

1.8

1.7

—

Dermatitis herpetiformis

446

1.38

1.52

1.5

1.6

—

Other and unspecified acquired haemolytic anaemias

171

1.63

1.52

1.5

1.6

—

Other disorders of patella

944

8795

1.08

1.52

1.6

1.7

—

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

5220

34390

1.03

1.51

1.9

1.6

—

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

926

8346

1.08

1.51

2.0

1.7

—

Infection of intervertebral disc (pyogenic)

116

1.76

1.51

1.9

1.5

—

Cerebral arteritis

2.18

1.51

1.3

1.8

—

Retrobulbar neuritis in diseases classified elsewhere

245

0.52

1.51

1.3

1.7

—

Nummular dermatitis

218

1873

1.18

1.50

1.6

—

Relapsing fevers

1.97

1.50

2.0

1.6

—

Allergic urticaria

511

4652

1.12

1.49

1.7

—

Gonarthrosis, primary, with knee surgery

607

4519

1.10

1.49

1.2

1.4

—

Use of levodopa decarboxylase inhibitor

120

973

1.24

1.49

1.2

1.4

—

Squamous cell neoplasms and carcinomas of the skin

776

1.27

1.49

1.4

1.3

—

Nystagmus and other irregular eye movements

596

0.70

1.49

1.7

1.6

—

Idiopathic urticaria

144

1207

1.24

1.48

1.8

1.7

—

Reimbursement for rheumatic diseases

2372

22632

1.05

1.48

1.6

1.7

—

Moderate visual impairment, binocular

472

1.35

1.48

1.8

1.6

—

Other specified transport accidents

266

1.54

1.48

2.1

1.8

—

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

428

0.65

1.48

1.1

1.3

—

Juvenile osteochondrosis

266

2343

1.17

1.47

1.9

1.8

—

Cervicocranial syndrome

386

3454

1.13

1.47

1.7

—

Complications of genitourinary prosthetic devices, implants and grafts

739

1.29

1.47

1.9

1.6

—

Deep bite

611

5817

0.91

1.47

1.7

1.8

—

Calculus of kidney and ureter

762

7038

1.09

1.47

1.7

1.6

—

COPD (mode)

426

3030

1.12

1.46

1.5

—

Toxic encephalopathy

2.88

1.46

1.5

1.3

—

Somatoform disorder

836

7768

1.09

1.46

1.7

—

Bullous disorders

136

1124

1.22

1.46

1.6

—

Malignant melanoma, excluding all cancers (controls excluding all cancers)

283

2480

1.15

1.46

1.5

—

Opening and dilatation of root channel of tooth

370

3317

1.13

1.46

1.6

1.7

—

Epileptic seizures related to drugs

147

0.44

1.45

2.0

1.8

—

Type 1 diabetes, strict definition, subgroup 2

147

0.44

1.45

1.4

1.8

—

Benign neoplasm: Transverse colon

132

1086

1.22

1.45

1.5

—

Early lumbar disc prolapse, operated

573

6247

0.91

1.45

1.7

—

Benign neoplasm of eye and adnexa

237

2055

1.16

1.45

1.7

1.6

—

Nontraumatic intracranial haemmorrhage

263

2292

1.15

1.45

1.5

—

Urolithiasis

805

7456

1.08

1.45

1.7

1.6

—

Explicit viral Sepsis

3.52

1.45

2.4

1.5

—

Arterial embolism and thrombosis of lower extremity artery

353

1.40

1.45

1.8

1.6

—

Other congenital malformations of ear

182

1582

1.23

1.44

1.8

—

Anorexia

764

1.29

1.44

1.7

—

Malignant neoplasm of other and unspecified parts of biliary tract, excluding all cancers (controls excluding all cancers)

154

0.45

1.44

1.1

1.4

—

Monocytic leukaemia

2.19

1.44

1.8

1.6

—

Stroke, including SAH

1040

7183

1.07

1.44

1.5

—

Mental and behavioural disorders due to cocaine

2.05

1.43

2.9

1.7

—

Cholera

364

0.63

1.43

1.5

1.3

—

286

2565

1.18

1.43

2.0

1.8

—

Alcohol withdrawal state with delirium

122

998

1.23

1.43

1.4

1.6

—

Etanercept

243

2777

0.86

1.43

1.6

1.7

—

Complications of procedures, not elsewhere classified

3799

31707

1.04

1.43

1.7

1.6

—

Other and unspecified disorders of autonomic nervous system

177

1.65

1.43

1.6

1.8

—

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

161

1911

0.84

1.43

1.5

—

Other acquired deformities of musculoskeletal system and connective tissue

134

1110

1.22

1.43

1.9

1.6

—

Carcinoma in situ of cervix uteri

1002

9431

1.08

1.43

1.7

—

STROKE

1367

8935

1.06

1.42

1.5

1.6

—

Secondary right heart disease

580

1.31

1.42

1.5

—

Benign neoplasm: Prostate

2.23

1.42

1.5

1.2

—

Other specified/unspecified systemic involvement of connective tissue

203

1747

1.18

1.41

1.5

1.6

—

Other/unspecified disorders of vestibular function

705

1.28

1.41

1.5

—

Other bullous disorders

680

1.29

1.41

1.6

1.7

—

Acute posthaemorrhagic anaemia

528

1.32

1.41

1.9

1.5

—

Primary gonarthrosis, bilateral

588

4699

1.10

1.41

1.4

—

Benign neoplasm: Ascending colon

162

1364

1.19

1.40

1.5

1.4

—

Ankle and foot

319

0.60

1.40

1.9

1.7

—

Cyst of spleen

100

1.94

1.40

1.9

1.7

—

Status post-ami

318

0.64

1.40

1.2

—

Autoimmune hyperthyroidism

287

2537

1.15

1.40

1.6

1.7

—

Hypertrophy of (infrapatellar) fat pad

351

1.42

1.40

1.5

1.7

—

Intermittent heterotropia

427

4692

0.89

1.40

1.8

1.7

—

Hypoparathyroidism

698

1.28

1.39

1.7

1.6

—

Complications of anaesthesia during labour and delivery

362

1.49

1.39

1.9

1.7

—

Drug-induced adrenocortical insufficiency

410

1.38

1.39

2.1

1.6

—

Plasmodium falciparum malaria

2.00

1.39

1.8

1.7

—

Emotional disorders starting during childhood or adolescence

722

6696

1.10

1.39

2.0

1.8

—

Hepatomegaly and splenomegaly, not elsewhere classified

309

1.45

1.39

2.3

1.7

—

Secondary systemic amyloidosis

2.70

1.39

2.2

1.6

—

Other hypertrichosis

250

0.55

1.38

1.9

1.8

—

Failed attempted abortion

138

1172

1.25

1.38

1.8

1.6

—

Heterophoria

544

4993

1.11

1.38

1.7

—

Monocytic leukaemia

2.15

1.38

1.8

1.6

—

Benign neoplasm: Caecum

125

1029

1.22

1.38

1.5

1.4

—

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

104

843

1.25

1.38

1.8

1.6

—

Psoriatic and enteropathic arthropathies

392

3526

1.12

1.38

1.6

1.7

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

445

4915

0.90

1.37

1.7

1.6

—

Clefts and syndromes for tooth agenesis exclusion, including avohilmo

177

2049

0.84

1.37

1.8

—

Other bursopathies

296

2617

1.14

1.37

1.6

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

243

2119

1.15

1.37

1.5

1.6

—

Stenosis and insufficiency of lacrimal passages

242

2113

1.16

1.37

1.7

1.6

—

Other and unspecified disorders of white blood cells

121

998

1.23

1.37

1.5

1.6

—

Cytomegaloviral hepatitis

1.93

1.36

1.7

—

Tick-borne viral encephalitis

1.94

1.36

1.0

1.8

—

Intercostal neuropathy

185

1.57

1.35

1.5

1.7

—

Acidosis

266

1.45

1.35

2.4

1.6

—

Viral conjunctivitis

119

987

1.24

1.35

1.8

1.7

—

Contact with sharp glass

271

2403

1.15

1.35

1.8

—

Acute nephritic syndrome

543

1.32

1.35

2.4

1.7

—

Other pulmonary heart/vessel disease

620

1.29

1.35

1.5

—

Acute pancreatitis

437

3954

1.11

1.35

1.7

1.6

—

Burkitt lymphoma, excluding all cancers (controls excluding all cancers)

3.16

1.35

1.4

2.6

—

Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

181

1560

1.19

1.34

1.6

1.7

—

Parodontitis, operation under 40 years and operation codes

1436

13713

1.07

1.34

1.8

—

Ischemic heart diseases

1426

8436

1.06

1.34

1.6

—

Use of bromocriptine

2.66

1.34

1.5

1.8

—

Entropion and trichiasis of eyelid

735

1.26

1.34

1.5

1.4

—

Mixed and other personality disorders

510

4673

1.11

1.33

1.8

1.7

—

Vascular dementia (mixed)

1.99

1.33

1.2

—

Carcinoma in situ of skin of other and unspecified parts of face

453

1.33

1.3

1.2

—

Adult-onset Still disease

155

1.65

1.33

1.4

1.7

—

Benign neoplasm: Stomach

136

1134

1.21

1.33

1.6

1.5

—

Rapidly progressive nephritic syndrome

2.02

1.33

1.4

1.8

—

Palmar fascial fibromatosis [Dupuytren]

171

1454

1.18

1.33

1.5

1.4

—

Enthesopathies of lower limb, excluding foot

803

7474

1.08

1.33

1.7

—

Contact with other and unspecified heat and hot substances

220

1.53

1.32

1.5

1.7

—

Other histiocytosis syndromes

2.49

1.32

1.5

1.6

—

Agoraphobia

257

2887

0.86

1.32

1.8

1.7

—

Acute appendicitis, no complications

3402

32795

1.04

1.32

1.7

—

Dermatitis due to substances taken internally

260

2295

1.15

1.32

1.9

1.7

—

Disorders of plasma-protein metabolism, not elsewhere classified

220

1.52

1.32

1.4

1.8

—

Chalazion

516

4725

1.10

1.32

1.7

—

Impacted teeth

2885

25982

1.05

1.32

1.8

—

Ankylosing hyperostosis [Forestier]

137

1.64

1.32

1.2

1.6

—

Caries in Clefts patients

733

0.74

1.31

1.5

1.7

—

Parodontitis, under 40 years and operation codes

1434

13703

1.07

1.31

1.8

—

Social phobias

769

8220

0.92

1.31

1.9

1.7

—

Disorders of magnesium metabolism

1.77

1.31

1.9

1.6

—

Sicca syndrome [Sjögren]

222

1934

1.16

1.31

1.7

1.6

—

Rheumatoid arthritis

830

8094

0.93

1.31

1.5

1.6

—

Cleft hard palate NOS

477

0.67

1.31

1.6

1.8

—

Benign neoplasm of other and unspecified endocrine glands

347

3111

1.12

1.30

1.6

—

Assault by sharp object

637

1.29

1.30

1.6

1.9

—

Toxic effect of other and unspecified substances

786

1.27

1.30

1.8

1.7

—

Erythema annulare centrifugum

2.40

1.30

1.8

1.5

—

Embedded teeth, including avohilmo

1010

10683

0.93

1.30

1.8

—

Other specified congenital malformation syndromes affecting multiple systems

914

0.77

1.29

1.8

—

Dermatopolymyositis (FG)

261

1.45

1.29

1.5

1.7

—

Folate deficiency anaemia

107

1.73

1.29

1.5

1.6

—

Abnormal weight loss

266

2351

1.14

1.29

1.7

—

Other symptoms and signs involving the circulatory and respiratory systems

247

2174

1.15

1.29

1.8

1.7

—

Convulsions of newborn

0.00

1.28

0.0

1.8

—

Cirrhosis of liver, NAS

536

1.30

1.28

1.7

1.5

—

Drug-induced hypoglycaemia without coma

478

1.33

1.28

1.7

—

Motor- or nonmotor-vehicle accident in traffic area

387

1.40

1.28

1.9

1.8

—

Autonomic disorders

557

1.30

1.27

1.6

1.7

—

Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers)

304

0.62

1.27

1.3

—

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

450

4114

1.11

1.27

1.9

1.7

—

Intestinal malabsorption

184

1590

1.18

1.27

2.2

1.7

—

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

1157

10922

1.06

1.27

1.7

—

Tumor necrosis factor alpha inhibitors

747

8007

0.92

1.26

1.6

1.7

—

Secondary parkinsonism, excluding more controls

261

1.43

1.26

1.2

1.7

—

Mesothelioma

118

0.42

1.26

1.2

1.4

—

Mesothelioma, excluding all cancers (controls excluding all cancers)

118

0.42

1.26

1.2

1.4

—

Filling of root of tooth

122

1019

1.22

1.26

1.7

—

Other and unspecified injuries of abdomen, lower back and pelvis

779

1.27

1.26

1.8

1.7

—

Polyclonal hypergammaglobulinaemia

2.87

1.25

2.0

1.5

—

Appendectomy

4085

38178

1.03

1.25

1.7

—

Renal agenesis and other reduction defects of kidney

182

1.57

1.25

2.0

1.8

—

Malignant neoplasm of nasal cavity and sinuses

1.96

1.25

1.3

1.6

—

Crohn's disease of small intestine

394

3579

1.12

1.25

1.8

1.7

—

Pulmonary oedema

179

1.53

1.25

2.5

1.5

—

Infarction of spleen

1.86

1.25

1.1

1.5

—

Dorsalgia

7085

39268

0.97

1.25

1.7

—

Unknown and unspecified causes of morbidity

296

2642

1.13

1.24

1.6

1.7

—

Other disorders of breast

645

5984

1.09

1.24

1.6

—

Respiratory tuberculosis, bacteriologically and histologically confirmed

254

1.44

1.24

1.7

1.6

—

135

1510

0.83

1.24

1.7

1.8

—

Knuckle pads

2.27

1.24

2.5

1.5

—

Dipeptidyl peptidase 4 (DPP-4) inhibitors

130

1088

1.20

1.24

1.6

1.4

—

Other nutritional anaemias

116

1.67

1.23

1.7

1.5

—

Myelodysplastic syndrome

2.08

1.23

1.2

1.5

—

Adenocarcinoma of pancreas, excluding all cancers (controls excluding all cancers)

189

0.52

1.23

1.6

1.3

—

Adenocarcinoma of pancreas

189

0.52

1.23

1.6

1.3

—

Non-small cell lung cancer, squamous, helper endpoint

265

0.60

1.23

1.1

1.3

—

Non-small cell lung cancer, squamous

265

0.60

1.23

1.1

1.3

—

Crohn disease

741

6914

1.08

1.23

1.8

1.7

—

Benign neoplasm: Rectosigmoid junction

385

0.67

1.23

1.5

1.4

—

Erosion of teeth

707

1.27

1.22

2.0

1.7

—

Dyspnoea

3830

30254

0.97

1.22

1.7

—

Carcinoma in situ of breast, other/unspecified

143

0.48

1.22

1.1

1.3

—

Malignant neoplasm of rectosigmoid junction

142

0.49

1.22

1.4

1.6

—

Pregnant state, incidental

2.52

1.22

1.6

1.4

—

Other hyperalimentation

1.83

1.22

1.5

1.7

—

Fibrosis and cirrhosis of liver

117

972

1.21

1.22

1.7

1.5

—

Convalescence

179

1547

1.17

1.22

1.7

1.6

—

Sequelae of injuries, of poisoning and of other consequences of external causes

927

8706

1.07

1.22

1.7

—

Fitting and adjustment of external prosthetic device

2.20

1.21

1.8

1.4

—

Open wound of ankle and foot

504

4634

1.10

1.21

1.8

1.7

—

Mental and behavioural disorders due to hallucinogens

322

1.43

1.20

2.0

1.8

—

Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence

636

5854

1.10

1.20

2.0

1.8

—

Parodontitis, under 40 years, or operation codes

1501

14392

1.06

1.20

1.8

1.7

—

Non-small cell lung cancer, squamous, excluding all cancers (controls excluding all cancers)

263

0.61

1.20

1.1

1.2

—

Presence of other devices

403

3655

1.11

1.20

1.6

1.5

—

Normal-pressure hydrocephalus

315

1.37

1.19

1.2

1.3

—

Microscopic polyangiitis

1.79

1.19

2.1

1.6

—

Subacute thyroiditis

143

1219

1.19

1.6

—

Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances

212

1867

1.16

1.19

1.7

—

Molar incisor enamel hypoplasia, with caries

267

1.44

1.19

1.7

1.8

—

Other and unspecified injuries of head

222

1954

1.15

1.19

1.6

1.7

—

Ill-defined and unknown causes of mortality

602

0.74

1.18

1.6

1.5

—

Seropositive rheumatoid arthritis, strict definition

329

3652

0.90

1.18

1.5

1.6

—

Migraine with aura

2198

21164

1.05

1.18

1.7

—

IPHG Phlebitis and thrombophlebitis of intracranial venous sinuses

0.00

1.18

0.0

1.6

—

Benign neoplasm of other and unspecified female genital organs

136

1154

1.20

1.18

1.6

—

Myeloproliferative diseases

146

1243

1.18

1.17

1.5

—

Allergic purpura

165

1428

1.18

1.17

1.8

1.7

—

Allergic bronchopulmonary aspergillosis (ABPA)

2.12

1.17

2.5

1.7

—

Parodontitis, under 40 years

1499

14382

1.06

1.17

1.8

1.7

—

Obsessive-compulsive disorder

733

6883

1.09

1.17

2.1

1.7

—

Endometriosis ASRM stages 3,4

1336

12712

1.06

1.17

1.7

1.6

—

Biological medication for rheuma

819

8723

0.93

1.17

1.6

1.7

—

Respiratory tuberculosis, confirmed

249

1.43

1.17

1.7

1.6

—

Postmenopausal osteoporosis with pathological fracture

342

1.35

1.16

1.1

1.3

—

Haemophilus septicemia

2.13

1.16

1.8

—

Intracerebral haemorrhage

145

1233

1.18

1.16

1.4

1.5

—

Defect, injury or illness of lumbar spine

203

0.55

1.16

1.5

1.7

—

Maternal care for known or suspected disproportion

224

1980

1.15

1.16

1.6

—

Fracture of lower leg, including ankle

2256

21608

1.04

1.16

1.8

1.7

—

Rheumatism, unspecified

346

3125

1.11

1.16

1.4

1.6

—

Emotional disorders and disorders of social functioning with onset specific to childhood

784

7305

1.09

1.16

2.1

1.8

—

Bulimia nervosa (incl. atypical)

526

4911

1.11

1.16

1.9

1.7

—

Other symptoms and signs involving general sensations and perceptions

146

1250

1.19

1.15

1.9

1.7

—

Benign neoplasm: Choroid

815

1.23

1.15

1.6

—

Carcinoma in situ of skin of upper limb, including shoulder

142

1.57

1.15

1.5

1.2

—

Benign neoplasm: Eye, unspecified

1.74

1.15

2.4

1.7

—

Benign neoplasm: Eye, unspecified

1.74

1.15

2.4

1.7

—

TMD related operations

893

8406

1.07

1.15

1.7

—

Toxic effect of carbon monoxide

540

1.29

1.15

1.6

1.7

—

Benign neoplasm: Urinary organ, other/unspecified

2.09

1.15

1.5

—

Pediculosis and phthiriasis

129

1.66

1.15

3.3

1.9

—

Congenital malformations of cardiac septa

298

3198

0.89

1.15

1.7

1.8

—

Other hearing loss

437

3922

1.10

1.15

1.5

1.6

—

Oral lichen ruber planus, including avohilmo

116

971

1.21

1.15

1.4

1.5

—

110

1262

0.82

1.14

1.7

1.8

—

Burkitt lymphoma

2.68

1.14

1.4

2.5

—

Burkitt lymphoma, helper endpoint

2.68

1.14

1.4

2.5

—

Congenital deformities of feet

134

1560

0.84

1.14

2.0

1.8

—

Malignant neoplasm of other and unspecified female genital organs

114

0.43

1.14

1.0

1.3

—

Benign neoplasm: Skin of trunk

140

1196

1.19

1.13

1.8

1.6

—

Myocardial infarction

653

4348

1.08

1.13

1.5

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

804

5869

0.93

1.13

1.5

—

Disorders of myoneural junction and muscle in diseases classified elsewhere

144

1.57

1.13

1.5

1.6

—

Syncope and collapse

1762

14944

1.05

1.12

1.7

—

Transient retinal artery occlusion

2.06

1.12

1.9

1.6

—

Crohn's disease NAS

338

3066

1.12

1.9

1.7

—

Coeliac disease

600

5577

1.09

1.12

1.7

—

Erectile dysfunction, exclusion

2.33

1.12

2.1

1.7

—

Prepatellar bursitis

102

846

1.22

1.12

1.8

1.7

—

Other lack of coordination

338

1.36

1.12

1.3

1.6

—

Atypical virus infections of central nervous system

144

1.56

1.11

2.4

1.5

—

Unspecified event, undetermined intent

131

1119

1.20

1.11

1.7

1.8

—

Benign neoplasm: Urinary organ, other/unspecified

2.03

1.11

1.5

—

Carcinoma in situ of colon

136

0.51

1.11

2.1

1.4

—

Other infective otitis externa

221

1955

1.14

1.11

1.8

1.6

—

Pemphigus erythematosus

2.36

1.11

1.4

1.7

—

Other infiltrative disorders of skin and subcutaneous tissue

121

1.64

1.11

1.6

1.7

—

Respiratory disorders in diseases classified elsewhere

287

1.39

1.11

1.3

1.6

—

Abscess of Bartholin gland

205

1817

1.16

1.11

1.7

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

4734

33037

1.03

1.11

1.7

—

Anosmia

385

1.33

1.11

1.5

—

Malignant neoplasm of other connective and soft tissue

364

1.34

1.11

1.8

1.7

—

Malignant neoplasm of other and ill-defined digestive organs, excluding all cancers (controls excluding all cancers)

136

0.51

1.11

1.9

1.4

—

Dislocation, sprain and strain of joint and ligaments of hip

748

1.23

1.11

1.7

1.6

—

Dislocation, sprain and strain of joints and ligaments of thorax

140

1201

1.19

1.11

1.7

—

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder

293

0.64

1.11

1.3

—

Primary ovarian failure

106

1252

0.82

1.10

1.6

1.7

—

Acute pancreatitis (for exclusion)

437

4003

1.10

1.7

1.6

—

Hypoplasia of dental enamel, including avohilmo

298

1.40

1.10

1.7

1.8

—

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

122

1029

1.19

1.10

1.7

1.5

—

Hypertensive encephalopathy

2.26

1.10

1.3

1.7

—

Carcinoma in situ of skin

656

1.24

1.10

1.7

1.4

—

Herpesviral keratitis and keratoconjunctivitis

131

1116

1.19

1.10

1.7

1.6

—

Lesion of lateral popliteal nerve

137

1171

1.18

1.09

1.5

1.7

—

Polyarteritis with lung involvement [Churg-Strauss]/EGPA

1.75

1.09

1.5

1.6

—

Intracranial and intraspinal phlebitis and thrombophlebitis

0.00

1.09

0.0

1.6

—

Other deformity of hallux (acquired)

129

1.59

1.08

1.9

1.5

—

Valvular operations

200

1755

1.14

1.08

1.4

1.6

—

Other disorders originating in the perinatal period

549

1.29

1.08

1.7

1.8

—

Complications of anaesthesia during the puerperium

315

1.44

1.08

1.6

1.7

—

Thyrotoxicosis with diffuse goitre

666

6224

1.08

1.6

1.7

—

Dislocation, sprain and strain of joints and ligaments of head

268

2413

1.13

1.08

1.8

1.7

—

Other disorders of nervous system

118

996

1.19

1.07

1.5

1.6

—

Exclusion endpoint for supernumerary teeth

899

0.79

1.07

1.6

1.8

—

Brain astrocytoma

211

0.58

1.07

1.3

1.7

—

Use of interferon beta-1a

111

1305

0.83

1.07

1.4

1.7

—

Ectropion of eyelid

253

1.39

1.07

1.2

1.3

—

Fracture of foot, except ankle

1393

13307

1.05

1.06

1.8

1.7

—

Disorders of muscles

380

3472

1.10

1.06

1.7

—

Nonspecific lymphadenitis

239

2133

1.13

1.06

1.7

—

Moderate visual impairment, monocular

115

1.65

1.05

1.2

1.8

—

Thyroiditis

322

2924

1.11

1.05

1.6

—

Trigeminal neuralgia

170

1483

1.16

1.05

1.6

—

Carcinoma in situ of prostate

2.00

1.05

1.1

1.3

—

Benign neoplasm: Stomach

136

1164

1.17

1.05

1.6

1.5

—

Other congenital malformations of skin

227

2027

1.14

1.05

1.5

1.7

—

Emotional disorders starting during childhood or adolecense, excluding more controls

720

6665

1.09

1.05

2.0

1.7

—

Female infertility, uterine origin

243

1.45

1.04

2.0

1.7

—

Arthropathies

7886

39349

1.02

1.04

1.7

—

Cauda equina syndrome

370

1.33

1.04

1.4

1.7

—

Disorders of eyelid, lacrimal system and orbit

3362

27163

0.97

1.04

1.7

1.6

—

Brain astrocytoma, excluding all cancers (controls excluding all cancers)

209

0.58

1.03

1.3

1.7

—

Systemic sclerosis (FG)

511

1.27

1.03

1.3

1.6

—

Other and unspecified injuries of neck

536

1.29

1.03

1.9

1.7

—

Benign neoplasm of other and unspecified female genital organs

136

1170

1.18

1.03

1.6

—

Mixed connective tissue disease

228

2033

1.13

1.03

1.5

1.6

—

Use of amantadine

274

0.65

1.03

1.2

1.6

—

Burns and corrosions of external body surface, specified by site

529

4915

1.09

1.03

1.8

—

Exposure to excessive natural heat

1.83

1.03

1.3

1.7

—

Exclusion endpoint for clefts

1126

0.82

1.03

1.9

1.8

—

Benign neoplasm: Skin of other and unspecified parts of face

265

2380

1.12

1.02

1.7

1.6

—

Migraine without aura and triptan purchases

1468

15297

0.95

1.02

1.7

—

LSIL lesion of the vagina

578

1.26

1.02

1.5

1.6

—

Hereditary deficiency of other clotting factors

400

1.33

1.02

1.8

1.7

—

Disorders of optic nerve, not elsewhere classified

361

1.32

1.02

1.7

1.6

—

Benign neoplasm: Skin of trunk

140

1209

1.17

1.02

1.8

1.6

—

Adenomyosis (Endometriosis of uterus)

425

3910

1.09

1.02

1.6

—

Other specified disorders of external ear

547

1.26

1.02

1.7

1.6

—

Pneumonia due to Streptococcus pneumoniae

135

1162

1.18

1.01

1.8

1.7

—

Implicit parasitic Sepsis

116

1.62

1.01

2.9

1.6

—

Other conditions originating in the perinatal period

2.15

1.01

1.9

2.1

—

Type 1 diabetes, wide definition

1220

12775

0.95

1.01

1.9

1.7

—

Mixed disorders of conduct and emotions, excluding more controls

350

3235

1.12

1.01

2.2

1.7

—

Constitutional tall stature

544

0.73

1.01

1.8

—

Benign neoplasm: Parotid gland

130

1512

0.85

1.01

1.5

1.6

—

Calcinosis cutis

2.07

1.01

2.0

1.7

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

287

2198

1.11

1.01

1.5

—

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

545

5863

0.93

1.01

1.5

1.6

—

Telogen effluvium

1.87

1.00

1.9

1.6

—

Coronary angioplasty

401

3359

0.91

1.00

1.5

—

Carcinoma in situ of colon

131

0.53

1.00

2.1

1.4

—

Use of trihexyphenidyl

0.00

1.00

0.0

1.8

—

Carcinoma in situ of breast, other/unspecified

132

0.52

1.00

1.1

1.3

—

Mental disorders, not otherwise specified

630

5910

1.08

1.00

1.9

1.7

—

Functional disorders of polymorphonuclear neutrophils

2.52

1.00

1.7

—

Burn and corrosion of wrist and hand

192

1702

1.15

1.00

1.8

—

Benign neoplasm: Skin of ear and external auricular canal

730

1.22

1.00

2.4

1.6

—

Accidental poisoning by and exposure to alcohol

157

1382

1.17

1.00

2.0

1.8

—

Other ulcerative colitis

232

2585

0.89

0.99

1.6

1.7

—

Common variable immunodeficiency with predominant abnormalities of T-cell numbers and function

0.00

0.99

0.0

1.6

—

Actinomycosis

1.76

0.99

2.5

1.8

—

Malnutrition in pregnancy

2.62

0.99

1.3

1.7

—

Atopic dermatitis, strict definition

2981

28394

1.04

0.99

1.8

1.7

—

Atrial septal defect

142

1619

0.86

0.99

1.5

1.7

—

Thyroiditis, ILD-related definition

632

5924

1.08

0.98

1.6

1.7

—

Carcinoma in situ of vulva

200

1.45

0.98

1.7

—

Phobic anxiety disorders

1236

12907

0.95

0.98

1.9

1.7

—

Carcinoma in situ of prostate

1.84

0.98

1.1

1.3

—

Other and unspecified diseases of blood and blood-forming organs

497

1.27

0.98

1.9

1.6

—

Cysts of oral region, not elsewhere classified

137

1185

1.17

0.98

1.9

1.6

—

Mixed disorders of conduct and emotions

350

3241

1.12

0.98

2.2

1.8

—

Other and unspecified disorders of binocular movement

298

1.38

0.97

1.7

—

Benign neoplasm of major salivary glands

157

1796

0.87

0.97

1.5

1.6

—

Cerebral cysts

308

2808

1.11

0.97

1.6

1.7

—

IBD (strict) with PSC

462

0.73

0.97

1.8

—

Abnormal findings in bronchial washings nasal secretions pleural fluid sputum throat scrapings

1.84

0.97

1.2

1.5

—

Short Achilles tendon (acquired)

789

0.80

0.97

1.6

1.7

—

All dysplastic lesions of the vulva

145

1261

1.16

0.97

1.5

1.6

—

Wilms' tumor

142

0.55

0.97

1.5

1.7

—

Wilms' tumor, excluding all cancers (controls excluding all cancers)

143

0.54

0.97

1.5

1.6

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

209

1857

1.13

0.97

1.7

1.6

—

Dislocation, sprain and strain of joints and ligaments of knee

3651

34816

0.97

1.6

1.7

—

Other Crohn's disease

394

3633

1.10

0.97

1.9

1.7

—

Postinfectious hypothyroidism

101

1.63

0.97

1.3

1.7

—

Vaginal lichen planus

1.82

0.96

1.3

—

Other and unspecified acne

128

1116

1.19

0.96

1.7

1.8

—

Benign neoplasm: Skin of ear and external auricular canal

733

1.21

0.96

2.4

1.6

—

Torsion of ovary, ovarian pedicle and fallopian tube

168

1486

1.16

0.96

1.7

—

Congenital malformation syndromes predominantly affecting facial appearance

214

0.60

0.96

1.9

1.7

—

Vascular dementia (undefined)

115

1.56

0.96

1.1

—

Congenital malformations of heart and great arteries

591

6110

0.93

0.96

1.7

—

Family history of mental and behavioural disorders

155

1.59

0.96

1.6

1.8

—

Malignant neoplasm of accessory sinuses

2.32

0.96

1.3

1.5

—

Other specified and unspecified disorders of choroid

1.71

0.95

1.4

1.6

—

Small kidney of unknown cause

1.86

0.95

1.9

—

Cholecystitis

255

2295

1.12

0.95

1.6

—

Malignant neoplasm of tonsil, excluding all cancers (controls excluding all cancers)

183

1.44

0.95

1.3

1.5

—

Unspecified misadventure during surgical and medical care

147

1281

1.16

0.95

1.9

1.6

—

Internuclear ophthalmoplegia

127

1.58

0.95

1.3

1.7

—

Other renal tubulo-interstitial diseases

681

1.22

0.95

1.9

1.5

—

Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)

217

1.40

0.95

1.5

1.6

—

Thalassaemia

249

1.43

0.95

1.7

—

Open wound of abdomen, lower back and pelvis

169

1494

1.15

0.94

1.9

1.7

—

Other disorders of binocular movement

177

1575

1.16

0.94

1.7

—

Sequelae of complication of pregnancy, childbirth and the puerperium

2.42

0.94

2.1

1.7

—

Paraplegia, diplegia of upper limbs

518

1.26

0.94

1.6

—

Congenital malformations of genital organs

852

8042

1.07

0.94

1.8

1.7

—

Fourth [trochlear] nerve palsy

491

1.26

0.94

1.8

1.6

—

Foreign body on external eye

482

5186

0.92

0.94

1.6

1.8

—

Cleft lip

179

0.57

0.94

1.3

2.0

—

Disorders of globe

392

1.29

0.94

1.6

—

Blood alcohol or alcohol intoxication level

153

1346

1.16

0.94

2.0

1.8

—

Other menopausal disorders

553

2964

1.08

0.94

1.4

—

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

134

1158

1.16

0.94

1.6

1.5

—

Carcinoma in situ of skin of upper limb, including shoulder

150

1.48

0.94

1.5

1.2

—

Preparation and fitting of bite rail to mouth

695

6546

1.07

0.94

1.7

—

Myositis

618

1.23

0.93

1.7

1.6

—

Rhinophyma

1.76

0.93

2.9

1.4

—

Chronic suppurative otitis media

249

2754

0.89

0.93

1.6

1.7

—

Exclusions for E4_PCOS_BROAD

813

7687

1.06

0.93

1.7

—

Kyphosis

262

1.36

0.92

1.6

1.7

—

Schizophrenia, schizotypal and delusional disorders

1695

17601

0.96

0.92

1.8

1.7

—

Adenocarcinoma and papillary adenocarcinoma of stomach

220

0.63

0.92

2.1

1.3

—

Vitamin B12 deficiency anaemia

154

1347

1.15

0.92

1.8

1.5

—

Contusion of ankle

206

2292

0.88

0.92

1.7

1.8

—

Chondromalacia

761

0.80

0.92

1.4

1.6

—

Focal epilepsy

755

7990

0.94

0.92

1.6

1.7

—

Cleft lip, lip and palate or palate

1067

0.83

0.91

1.5

1.8

—

Postprocedural disorders of eye and adnexa, not elsewhere classified

1.99

0.91

1.3

1.8

—

Mandibular retrognathia

454

4214

1.09

0.91

1.7

—

Vitamin deficiency

165

1456

1.15

0.91

1.6

1.7

—

Vitamin deficiency, wide

165

1456

1.15

0.91

1.6

1.7

—

Malignant neoplasm of cervix uteri

625

0.78

0.91

1.5

1.6

—

Findings of drugs and other substances, not normally found in blood

1.67

0.91

1.9

1.8

—

Benign neoplasm: Rectosigmoid junction

360

0.72

0.91

1.5

1.4

—

Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers)

219

0.63

0.91

2.1

1.4

—

Hypermetropia

375

3461

1.10

0.91

1.9

1.7

—

Other and unspecified disorders of pigmentation

256

1.38

0.91

1.9

1.6

—

Abrasion of teeth

1162

8945

0.95

0.91

1.8

1.6

—

Acute inflammation of orbit

283

1.36

0.91

1.8

—

Ehlers-Danlos syndrome

770

0.79

0.90

1.6

1.7

—

Benign neoplasm: Skin of lower limb, including hip

639

1.22

0.90

1.8

1.6

—

Spondyloarthritis

787

7443

1.06

0.90

1.6

1.7

—

Nontoxic multinodular goitre

361

3317

1.09

0.90

1.4

1.5

—

Use of dimethyl fumarate

629

0.78

0.90

1.3

1.7

—

Other and unspecified parapsoriasis

1.95

0.90

1.4

—

Other/unspecified seropositive rheumatoid arthritis

551

5894

0.93

0.90

1.5

1.6

—

Malignant neoplasm of accessory sinuses, excluding all cancers (controls excluding all cancers)

1.95

0.90

1.3

1.4

—

Endometroid carcinoma of ovary, excluding all cancers (controls excluding all cancers)

130

0.53

0.90

1.1

1.5

—

Acquired absence of organs, not elsewhere classified

229

1.38

0.89

2.7

1.7

—

Benign neoplasm: Choroid

840

1.19

0.89

1.6

1.5

—

Malignant neoplasm of corpus uteri

574

0.78

0.89

1.2

1.3

—

Exposure to controlled fire, not in building or structure

111

0.51

0.89

1.3

1.6

—

Dementia due to Parkinsons disease, excluding more controls

1.70

0.89

1.2

—

Ulcerative proctitis

338

3111

1.10

0.89

1.7

—

Event of undetermined intent

338

3111

1.10

0.89

2.0

1.8

—

Other and unspecified disorders of adult personality and behaviour

421

1.31

0.89

2.0

1.7

—

Hallux valgus (acquired)

698

5366

0.94

0.89

1.5

1.6

—

Benign neoplasm: Scrotum

1.91

0.89

1.4

1.7

—

Oesophageal obstruction

395

1.28

0.89

1.3

1.5

—

Pedestrian injured in collision with railway train or railway vehicle

2.11

0.89

2.8

1.4

—

Benign neoplasm: Kidney

449

1.26

0.89

1.6

1.4

—

Exposure to ignition of highly flammable material

129

1.54

0.88

1.3

2.0

—

Asthma (diagnoses ohter than nonallergic)

5006

43727

0.98

0.88

1.7

—

Schizophrenia or delusion

1696

17590

0.96

0.88

1.8

1.7

—

Other factor of the environment

462

1.27

0.88

2.4

1.7

—

Emergency coronary revascularization (for ACS)

587

4505

0.93

0.88

1.6

1.5

—

Other adrenocortical overactivity

492

0.75

0.87

1.7

1.8

—

Other disorders starting during childhood or adolecense, excluding more controls

617

5628

1.08

0.87

1.9

1.7

—

Glucagon-like peptide-1 (GLP-1) analogues

803

6245

1.06

0.87

1.7

1.5

—

Other disorders starting during childhood or adolescence

617

5790

1.08

0.87

1.9

1.8

—

Other peripheral vertigo

197

1761

1.13

0.87

1.4

1.6

—

Hereditary motor and sensory neuropathy

261

0.67

0.87

1.3

1.7

—

Toxoplasmosis

189

1.43

0.86

1.3

1.8

—

Crossbite

404

4027

0.92

0.86

1.7

1.8

—

Shigellosis

1.63

0.86

3.1

1.8

—

Atrioventricular septal defect

199

0.62

0.86

1.3

1.6

—

Benign neoplasm: Skin of lower limb, including hip

643

1.21

0.86

1.8

1.6

—

Autoimmune diseases related-to ILD

4809

41384

1.02

0.86

1.7

—

Barrett oesophagus

523

1.23

0.86

1.3

1.4

—

SLE (Finngen)

138

1211

1.16

0.85

1.6

—

Oral leukoplakia

196

1.39

0.85

2.3

1.5

—

Family history of malignant neoplasm

456

4887

0.93

0.85

1.7

1.6

—

Retinoschisis and retinal cysts

239

1.35

0.85

1.6

1.4

—

Asthma, unspecified (mode), excluding more controls

2428

19650

0.97

0.85

1.6

—

Seropositive rheumatoid arthritis, wide

562

5992

0.93

0.85

1.5

1.6

—

Congenital malformations of gallbladder, bile ducts and liver

180

1.42

0.85

2.0

1.6

—

Chronic myeloid leukaemia [CML], BCR/ABL-positive

146

1.47

0.85

1.4

1.7

—

Aortic arch syndrome [Takayasu]

1.75

0.85

1.2

1.7

—

Schizoaffective disorder

355

3837

0.92

0.84

1.8

1.7

—

Qualitative platelet defects

114

1.56

0.84

1.3

1.7

—

Other protozoal intestinal diseases

602

1.23

0.84

2.4

1.6

—

Abscess of tendon sheath

190

1.42

0.84

1.9

1.7

—

Optic atrophy

476

0.76

0.84

1.4

1.6

—

Ingrowing nail

238

2161

1.11

0.84

1.9

1.7

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

1558

15014

1.04

0.84

1.8

1.7

—

Colitis, primary sclerosing

606

0.79

0.84

1.8

—

Traumatic cerebral oedema

123

1.55

0.83

1.7

1.6

—

Small cell lung cancer, excluding all cancers (controls excluding all cancers)

139

0.57

0.83

1.5

1.3

—

Small cell lung cancer, helper endpoint

140

0.57

0.83

1.5

1.3

—

Small cell lung cancer

140

0.57

0.83

1.5

1.3

—

Diffuse brain injury

143

1260

1.15

0.83

1.7

—

Other misadventures during surgical and medical care

564

1.23

0.83

1.6

1.7

—

Toxic liver disease

365

1.28

0.83

2.1

1.6

—

Adhesive capsulitis of shoulder

300

2747

1.10

0.83

1.5

—

Nasal polyp

479

4472

1.08

0.83

1.4

1.6

—

Oral lichen ruber planus, hypothyreosis or thyroxin

241

1.35

0.82

1.2

1.5

—

Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

1.63

0.82

1.3

1.7

—

Benign neoplasm: Cerebral meninges

142

1248

1.14

0.82

1.3

1.5

—

Other sex chromosome abnormalities, male phenotype, not elsewhere classified

1.63

0.82

2.1

2.0

—

Symptoms and signs involving emotional state

178

1597

1.14

0.82

1.7

—

Other recurrent vertebral subluxation

0.00

0.82

0.0

2.0

—

Unspecified behavioural syndromes associated with physiological disturbances and physical factors +Physiological and behavioural factors associated with disorders of diseases classified elsewhere

907

0.83

0.82

1.8

1.7

—

Malignant neoplasm of urinary organs

109

940

1.16

0.81

1.7

1.4

—

Olecranon bursitis

848

1.17

0.81

2.3

1.7

—

Disorder of bilirubin metabolism, other/unspecified

0.00

0.81

0.0

1.4

—

Dermatitis due to ingested food

366

3283

1.10

0.81

1.8

—

Mucosal proctocolitis

640

6770

0.94

0.81

1.7

—

Drug-induced interstitial lung disorders, unspecified

1.91

0.81

1.5

1.7

—

Malignant neoplasm of other endocrine glands and related structures, excluding all cancers (controls excluding all cancers)

125

0.54

0.81

1.7

—

Disorders of continuity of bone

384

3565

1.09

0.81

1.7

—

141

1.50

0.81

2.1

1.9

—

Malignant neoplasm of bone and articular cartilage of other and unspecified sites, excluding all cancers (controls excluding all cancers)

216

1.37

0.81

1.6

1.7

—

Hookworm diseases

2.10

0.81

1.9

—

Monosomies and deletions from the autosomes, not elsewhere classified

134

0.56

0.81

1.3

1.7

—

Lifestyle-related condition

422

1.27

0.81

2.4

1.7

—

Chondrocostal junction syndrome [Tietze]

151

1340

1.14

0.81

1.5

1.7

—

Animal-rider or occupant of animal-drawn vehicle injured in transport accident

102

1163

0.84

0.81

1.6

1.7

—

Carcinoma in situ of skin of scalp and neck

122

1.49

0.80

1.3

1.2

—

Pyoderma gangrenosum

244

1.36

0.80

1.3

1.7

—

Unspecified contact dermatitis due to drugs in contact with skin

2.39

0.80

1.8

1.4

—

Neuroendocrine tumor and carcinoma of small intestine, excluding all cancers (controls excluding all cancers)

149

0.60

0.80

1.8

1.4

—

Benign neoplasm: Ill-defined sites within the digestive system

0.50

0.80

1.6

1.5

—

Bacterial pneumonia (organism specified)

1433

12556

1.04

0.80

1.7

—

Sequelae of injuries of lower limb

348

3220

1.09

0.80

1.6

1.7

—

Malignant neoplasm of gallbladder

0.00

0.80

0.0

1.5

—

Neuroendocrine tumor and carcinoma of stomach

1.85

0.80

1.7

1.5

—

Parodontitis or operation codes

3184

24057

0.97

0.80

1.7

1.6

—

Lesion of radial nerve

731

1.19

0.79

1.5

1.6

—

Endometroid carcinoma of ovary

121

0.57

0.79

1.1

1.5

—

Assault by drugs, medicaments and biological substances

1.79

0.79

1.4

1.7

—

Other intracranial haemorrhages

242

1.33

0.79

1.4

1.5

—

Toxic effect of alcohol

604

1.21

0.79

1.7

—

Lateral epicondylitis

305

3314

0.92

0.79

1.5

1.6

—

Hereditary hypogammaglobulinemia

1.60

0.79

2.0

1.4

—

Mixed hyperlipidaemia

529

1.22

0.79

1.7

1.5

—

Injury of intra-abdominal organs

126

1109

1.16

0.79

1.7

1.8

—

Other specified and unspecified disorders of conjunctiva

253

1.34

0.79

1.6

1.7

—

Fracture of shoulder and upper arm

1302

12507

1.04

0.79

1.7

—

Contact with other hot metals

468

1.24

0.79

1.7

—

Radial styloid tenosynovitis [de Quervain]

277

2544

1.10

0.78

1.6

1.7

—

Myeloproliferative diseases (CML excluded)

125

1094

1.15

0.78

1.5

—

Other specified/unspecified hearing loss

159

1414

1.13

0.78

1.6

—

Pneumothorax

151

1339

1.13

0.78

1.8

1.7

—

Alzheimer’s disease (undefined)

0.00

0.78

0.0

1.1

—

Acne vulgaris

1029

9891

1.06

0.78

1.9

1.8

—

Lesion of ulnar nerve

384

3567

1.08

0.78

1.7

—

Glaucoma secondary to drugs

1.71

0.78

1.4

1.7

—

Parodontitis

3180

24039

0.97

0.78

1.7

1.6

—

Alcohol induced polyneuropathy

115

1.50

0.78

1.3

1.4

—

Other congenital malformations of skull and face bones

205

0.64

0.78

2.0

1.7

—

Toxic effect of other inorganic substances

2.27

0.78

1.2

1.8

—

Cleft palate

854

0.82

0.78

1.5

1.8

—

Carcinoma in situ of skin of scalp and neck

123

1.47

0.78

1.3

1.2

—

Lung diseases due to external agents

220

1992

1.11

0.78

1.5

1.6

—

Carcinoma in situ of skin

685

1.19

0.78

1.7

1.4

—

Other helminthiases

1.98

0.78

1.4

1.5

—

Other osteochondropathies

259

2826

0.91

0.78

1.8

1.7

—

Respiratory and cardiovascular disorders specific to the perinatal period

109

1111

0.86

0.78

1.8

—

Malignant neoplasm of bladder

462

0.78

1.2

1.3

—

Achalasia of cardia

370

0.75

0.77

1.5

1.6

—

Social disorders starting during childhood or adolecense, excluding more controls

774

1.21

0.77

2.2

1.8

—

Unspecified mental disorder

2374

24411

0.97

0.77

1.8

1.7

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Treponema pallidum Ab [Presence] in Serum

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS