This is a non-core endpoint: only basic statistics are computed.
Gangrene and necrosis of lung
J10_LUNGNECROSIS
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
10 |
4. Check minimum number of eventsNone |
10 |
5. Include endpointsNone |
10 |
6. Filter based on genotype QC (FinnGen only) |
8 |
Control definitions (FinnGen only)
- Control exclude
- J10_NECROTIC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J85
- Name in latin
- Necrosis pulmonis
Similar endpoints
↥List of similar endpoints to
Gangrene and necrosis of lung
based on the number of shared cases.
Similar with more cases:
- Suppurative and necrotic conditions of lower respiratory tract
- Other pulmonary diagnosis
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: unknown.
No upset table: unknown.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 263 | 84 | 175 |
| Only index persons | 158 | 58 | 100 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 61.42 | 64.70 | 59.89 |
| Only index persons | 58.09 | 56.91 | 58.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8 | - | 6 |
| Unadjusted period prevalence (%) | 0.00 | - | 0.00 |
| Median age at first event (years) | 60.12 | - | 69.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
11
7.84
2.25
3.0
1.4
—
—
—
0
0
5
11
7.84
2.25
3.0
1.5
—
—
—
0
0
0
17
0.00
0.45
0.0
2.0
—
516.53
—
0
17
0
11
0.00
0.23
0.0
2.4
—
—
—
0
0
0
11
0.00
0.23
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_LUNGNECROSIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have J10_LUNGNECROSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: J10_LUNGNECROSIS – Gangrene and necrosis of lung
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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