Disorders of male genital organs in diseases classified elsewhere

N14_MALEGENINOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only males

244368

2. Check conditions

None

244368

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N51*
  • Cause of death: ICD-10 N51*

2 out of 7 registries used, show all original rules.

273

4. Check minimum number of events

None

273

5. Include endpoints

None

273

6. Filter based on genotype QC (FinnGen only)

245

Control definitions (FinnGen only)

Control exclude
N14_MALEGEN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2125 - 2125
Only index persons 2038 - 2038
Unadjusted period prevalence (%)
Whole population 0.06 - 0.06
Only index persons 0.08 - 0.08
Median age at first event (years)
Whole population - - 34.45
Only index persons - - 34.35

-FinnGen-

Key figures

All Female Male
Number of individuals 245 - 245
Unadjusted period prevalence (%) 0.11 - 0.11
Median age at first event (years) 47.71 - 47.71

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
256
Matched controls
2560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N51.8*A60.0
ICD-10 Finland
Herpes simplex infection of the genitals in men
501.7
122.7
113
*
N51.2*B37.4
ICD-10 Finland
Candidal balanitis
276.9
64.4
63
*
N48.1
ICD-10 Finland
Balanoposthitis
19.5
57.9
48
30
J05AB11
ATC
valaciclovir; oral
7.2
44.7
84
163
N51.2
ICD-10 Finland
Balanitis in diseases classified elsewhere
215.2
36.8
37
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
7.0
31.7
55
96
J05AB01
ATC
aciclovir; systemic
5.1
29.8
81
214
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
8.5
28.0
39
53
J02AC01
ATC
fluconazole; systemic
4.6
26.6
84
248
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
4.1
24.9
95
321
KGH10
NOMESCO Finland
Operation for phimosis
216.0
19.8
20
*
N51.8
ICD-10 Finland
Other disorders of male genital organs in diseases classified elsewhere
216.0
19.8
20
*
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
23.1
19.1
27
13
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.7
18.5
48
119
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
35.9
18.3
23
7
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
21.1
17.2
25
13
N40
ICD-10 Finland
Hyperplasia of prostate
3.5
15.9
69
246
UKC02
NOMESCO Finland
Cystoscopy
4.2
15.4
46
127
XKD00
NOMESCO Finland
Uroflowmetry
4.0
14.2
46
134
G04CB01
ATC
finasteride; oral
4.0
13.3
42
120
J01MA02
ATC
ciprofloxacin; systemic
2.7
13.0
108
547
N03AF01
ATC
carbamazepine; oral, rectal
5.9
12.4
23
42
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.2
11.4
51
183
A63.0
ICD-10 Finland
Anogenital (venereal) warts
5.6
11.3
22
42
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.9
11.3
65
270
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
10.7
128
753
KED22
NOMESCO Finland
Transurethral resection of prostate
34.1
10.4
13
*
N02BF01
ATC
gabapentin; oral
3.8
10.3
33
95
G04CA01
ATC
alfuzosin; oral
2.9
10.1
57
233
N41.1
ICD-10 Finland
Chronic prostatitis
8.7
10.1
21
26
N02AX02
ATC
tramadol; systemic, rectal
2.3
9.8
122
722
N51.1
ICD-10 Finland
Disorders of testis and epididymis in diseases classified elsewhere
57.2
9.7
11
*
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
9.7
9.7
19
21
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.0
9.4
28
76
G04CA02
ATC
tamsulosin; oral
2.4
9.3
85
438
H04.10
ICD-10 Finland
Dry eye syndrome
3.6
9.2
32
97
N03AX12
ATC
[U] gabapentin; oral
2.9
9.1
48
188
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
9.0
135
855
J01MA01
ATC
ofloxacin; systemic
4.2
8.9
25
65
K08.80
ICD-10 Finland
Toothache NOS
3.8
8.8
28
80
D07AC01
ATC
betamethasone; topical
2.3
8.6
99
560
G04CB02
ATC
dutasteride; oral
3.7
8.3
28
83
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
8.0
8.3
18
24
N03AE01
ATC
clonazepam; systemic
4.3
8.3
22
55
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
8.2
51
218
Y04
ICPC
Penis symptom/complaint other
12.3
8.2
14
12
K30
ICD-10 Finland
Functional dyspepsia
3.3
7.9
31
102
M03BX02
ATC
tizanidine; oral
2.1
7.9
158
1100
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
7.9
88
490
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
7.8
30
97
N06AX21
ATC
duloxetine; oral
3.2
7.8
32
108
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.9
7.8
41
160
N48.8
ICD-10 Finland
Other specified disorders of penis
46.4
7.8
9
*
N03AX16
ATC
[U] pregabalin
2.4
7.6
60
287
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
7.6
97
568
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
7.5
65
325
J01DB01
ATC
cefalexin; oral
2.5
7.3
213
1699
J01DA01
ATC
[U] cefalexin
2.0
7.2
150
1047
M79.6
ICD-10 Finland
Pain in limb
2.1
7.1
108
672
J02AC02
ATC
itraconazole; systemic
2.7
7.0
41
169
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.2
7.0
19
48
M01AB05
ATC
diclofenac; systemic, rectal
2.1
7.0
176
1310
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
6.9
73
394
R31
ICD-10 Finland
Unspecified haematuria
3.1
6.7
29
101
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
6.7
75
415
L03
ICPC
Low back symptom/complaint
2.1
6.7
75
415
J01MA12
ATC
levofloxacin; systemic
2.4
6.6
49
227
G04BD12
ATC
mirabegron; oral
3.3
6.6
26
86
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
6.5
46
208
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
6.4
131
895
KED52
NOMESCO Finland
Visual laser resection of prostate
+∞
6.3
6
*
KGB00
NOMESCO Finland
Biopsy of penis
+∞
6.3
6
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
6.3
6
*
D07AD01
ATC
clobetasol; topical
2.5
6.2
42
186
R12
ICD-10 Finland
Heartburn
3.3
6.2
24
78
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.1
6.2
26
89
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.0
6.1
28
101
A02BC05
ATC
esomeprazole; systemic
2.0
6.1
93
573
D06BB04
ATC
podophyllotoxin; topical
3.3
6.1
23
74
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.6
6.0
36
150

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
152
3.94
15.34
2.0
2.0
—
—
—
0
0
47
150
3.61
12.69
3.8
4.4
7.37
7.33
ph
0.90
34
118
122
677
2.53
11.92
7.5
7.1
—
—
—
0
0
206
1529
2.78
9.92
10.6
9.2
76.21
80.66
u/l
0.63
199
1473
85
428
2.48
9.89
2.3
2.0
—
—
—
0
0
156
1042
2.27
9.19
8.5
7.6
0.21
0.21
e9/l
0.04
136
922
144
931
2.25
9.18
10.3
9.7
1.20
1.20
mmol/l
0.34
130
828
146
953
2.24
9.05
7.6
7.1
56.17
57.65
%
0.78
138
928
144
940
2.22
8.86
8.1
7.4
9.25
9.13
%
0.23
136
905
143
938
2.19
8.60
8.1
7.3
0.63
0.65
%
0.24
135
900
142
935
2.16
8.39
8.1
7.2
3.00
2.98
%
0.04
134
898
151
1021
2.17
8.30
7.7
7.0
0.04
0.04
e9/l
0.01
134
884
151
1022
2.16
8.26
7.7
7.0
0.63
0.61
e9/l
0.50
134
882
133
858
2.14
8.23
7.5
5.9
36.87
36.26
g/l
0.58
127
814
145
972
2.13
8.06
8.0
7.2
28.50
26.53
%
1.53
139
936
152
1039
2.14
8.01
7.7
7.3
1.91
1.83
e9/l
0.55
135
920
140
932
2.11
7.86
3.3
2.9
0.00
0.00
estimate
-0.00
13
184
140
937
2.09
7.69
3.3
2.9
0.00
9.77
estimate
0.50
15
179
129
842
2.07
7.54
9.5
9.1
1.20
1.20
mmol/l
0.33
120
791
90
513
2.16
7.52
2.3
2.4
—
0.00
—
0
12
140
945
2.06
7.43
3.4
2.9
0.00
1.82
estimate
0.50
14
165
240
2030
3.92
7.41
21.7
15.2
20.79
26.30
mg/l
2.02
209
1657
117
745
2.05
7.23
3.2
2.8
6.08
6.11
ph
0.10
65
435
13
13
10.46
7.12
1.4
1.0
—
—
—
0
0
24
73
3.52
6.88
1.4
1.3
—
—
—
0
0
137
940
1.98
6.71
15.7
13.0
1.22
1.23
inr
0.12
117
776
51
245
2.35
6.34
1.6
1.7
—
—
—
0
0
113
745
1.93
6.05
5.3
3.7
8.79
8.96
mmol/l
0.14
94
655
48
229
2.35
6.05
1.5
1.4
—
—
—
0
0
49
239
2.30
5.86
1.2
1.3
—
—
—
0
0
59
315
2.13
5.65
1.9
1.8
—
—
—
0
0
31
124
2.71
5.62
1.8
2.3
5.74
5.97
ph
0.63
17
74
69
394
2.03
5.52
3.3
4.1
1810.63
761.52
ng/l
0.34
51
314
121
836
1.85
5.45
2.9
2.8
—
—
estimate
—
0
0
27
102
2.84
5.44
3.4
3.7
—
—
—
0
0
211
1755
2.15
5.24
5.2
3.8
1.79
1.92
mu/l
1.11
189
1630
58
317
2.07
5.20
1.8
1.6
—
—
—
0
0
151
1128
1.83
5.18
12.0
11.7
4.00
4.18
e9/l
0.52
136
991
156
1180
1.82
5.11
7.6
6.8
7.02
6.87
mmol/l
0.34
149
1143
46
232
2.20
5.06
3.2
3.1
99.50
173.81
ug/g
1.87
38
199
94
615
1.84
4.94
4.5
3.0
54.78
66.12
u/l
0.85
89
587
114
792
1.79
4.90
2.2
2.0
99.55
91.31
pmol/l
0.87
57
463
84
532
1.86
4.89
2.2
2.5
0.00
0.18
estimate
0.52
11
144
69
412
1.92
4.80
2.0
1.9
0.98
1.59
mg/l
1.01
55
319
48
253
2.10
4.71
1.5
1.4
316.36
265.78
titre
0.32
11
45
91
597
1.81
4.70
5.0
4.6
—
—
—
0
0
16
48
3.49
4.69
1.8
1.5
240.63
249.86
ug/g
—
8
33
114
801
1.76
4.66
5.4
3.6
30.76
47.90
ng/l
1.02
84
568
22
82
2.84
4.55
2.6
2.2
—
—
—
0
0
97
656
1.77
4.49
4.8
3.8
32.38
53.28
mg/l
1.14
69
471
52
288
2.01
4.46
4.2
2.6
—
—
—
0
0
99
675
1.76
4.44
5.5
4.4
4.31
8.66
mg/mmol
1.52
64
467
171
1365
1.76
4.31
3.7
3.0
14.85
14.80
pmol/l
0.08
156
1261
19
68
2.94
4.22
2.5
2.8
—
—
—
0
0
118
859
1.69
4.11
1.8
1.9
1.50
1.49
mmol/l
0.04
106
735
165
1314
1.72
4.10
6.0
4.1
7.68
1.85
ug/l
0.55
151
1174
103
725
1.70
4.05
3.0
2.9
0.00
0.00
estimate
-0.00
11
159
68
439
1.75
3.59
2.9
2.4
13.82
14.40
nmol/l
0.25
57
410
9
17
5.45
3.54
1.6
1.1
—
—
—
0
0
15
52
3.00
3.53
1.1
1.1
—
—
—
0
0
92
653
1.64
3.39
4.6
3.6
24.81
91.56
e6/l
0.81
71
468
232
2089
2.18
3.38
24.9
18.5
4.02
4.02
mmol/l
0.15
226
2051
58
364
1.77
3.36
1.6
1.5
2.69
2.82
g/l
0.24
39
249
39
216
1.95
3.33
4.0
4.3
1.46
1.51
mmol/l
0.03
34
190
83
576
1.65
3.33
3.9
3.1
16.08
167.56
e6/l
0.73
66
437
92
661
1.61
3.19
2.2
2.1
—
—
—
0
0
81
564
1.64
3.19
4.4
3.9
2.34
2.34
mmol/l
0.14
76
520
32
169
2.02
3.12
1.7
2.9
77.73
66.72
e9/l
0.73
27
126
87
620
1.61
3.11
2.5
2.5
—
—
—
0
0
52
323
1.77
3.11
1.8
2.3
—
—
—
0
0
64
422
1.69
3.09
3.7
3.0
1.02
1.02
kg/l
0.19
43
264
39
222
1.89
3.08
1.8
1.7
—
—
—
0
0
8
16
5.12
3.07
2.0
1.5
—
—
—
0
0
243
2246
2.61
3.05
16.0
11.4
31.41
33.24
u/l
0.86
237
2204
27
135
2.12
3.04
11.1
21.2
17.15
16.09
%
0.72
27
127
230
2082
2.03
3.02
24.9
18.3
139.72
139.67
mmol/l
0.11
225
2047
80
563
1.61
2.99
3.0
3.0
352.20
376.32
umol/l
1.42
69
510
39
226
1.86
2.91
3.8
4.2
5.76
5.73
kpa
0.05
39
221
7
13
5.50
2.89
2.0
2.4
784.43
779.62
u/ml
—
7
13
11
33
3.44
2.85
1.1
1.3
—
—
—
0
0
43
259
1.79
2.84
1.3
1.3
1.43
13.55
u/ml
1.61
12
109
44
267
1.78
2.84
1.3
1.5
—
—
—
0
0
39
228
1.84
2.84
1.7
2.7
1.66
1.74
%
0.22
33
210
70
483
1.62
2.82
3.6
3.0
0.00
0.01
estimate
0.50
15
161
25
125
2.11
2.82
1.1
1.2
—
—
—
0
0
39
229
1.83
2.80
4.3
4.3
7.36
7.38
ph
0.65
22
130
73
513
1.59
2.72
4.7
4.9
88.16
86.76
%
0.21
73
505
232
2124
1.98
2.67
5.5
4.9
4.61
4.55
mmol/l
0.40
218
2017
13
49
2.74
2.66
1.6
1.4
—
—
—
0
0
44
274
1.73
2.60
1.5
1.2
10.60
38.71
iu/ml
—
9
85
234
2153
2.01
2.58
6.2
5.3
2.73
2.75
mmol/l
0.16
216
2035
26
137
2.00
2.57
3.0
4.5
24.58
24.01
mmol/l
0.46
26
137
6
11
5.55
2.56
1.5
1.0
—
—
—
0
0
231
2120
1.92
2.51
5.5
4.7
1.26
1.28
mmol/l
0.33
212
1999
103
796
1.49
2.46
3.1
2.7
179.77
191.82
ug/l
0.13
94
755
77
564
1.52
2.36
1.3
1.3
—
—
—
0
0
42
266
1.69
2.34
9.8
14.0
7.42
7.42
ph
0.24
21
144
41
260
1.69
2.27
9.9
14.3
1.47
0.65
mmol/l
1.10
35
211
7
19
3.76
2.16
1.0
1.2
—
—
—
0
0
14
62
2.33
2.11
1.2
1.1
—
—
—
0
0
62
443
1.53
2.11
2.2
2.2
2.52
2.94
mg/l
0.76
48
398
38
241
1.68
2.11
3.5
3.7
3.97
5.20
e9/l
0.58
29
210
57
400
1.55
2.11
3.2
2.4
2.17
2.52
e6/l
0.28
50
359
73
949
0.68
2.09
2.6
2.9
—
—
—
0
0
41
267
1.64
2.06
1.8
1.6
900.67
1026.85
nmol/l
0.56
28
211
19
97
2.04
2.06
6.2
10.2
1.75
1.69
%
0.13
19
89
232
2159
1.80
2.02
19.0
12.8
—
—
—
0
0
17
84
2.10
2.00
6.7
11.5
1.01
0.88
%
0.81
17
75
217
1987
1.60
1.99
8.1
5.9
41.16
39.13
mmol/mol
2.10
199
1897
34
213
1.69
1.98
10.2
13.1
1.32
1.37
mmol/l
0.18
34
208
15
71
2.18
1.96
2.8
2.4
23.94
24.94
mmol/l
0.74
15
71
18
92
2.03
1.95
1.4
1.2
—
—
—
0
0
8
27
3.02
1.95
1.4
1.6
581.13
1831.71
e6/l
—
8
17
23
130
1.85
1.89
2.9
3.1
0.56
0.62
%
0.53
23
130
19
101
1.95
1.86
8.7
3.0
—
—
—
0
0
29
177
1.72
1.86
1.8
2.3
11.42
12.10
ug/l
0.05
22
164
6
17
3.59
1.85
3.3
2.9
—
—
—
0
0
56
403
1.50
1.84
1.3
1.3
0.80
1.06
u/ml
0.45
13
127
40
267
1.59
1.83
1.6
1.8
—
—
—
0
0
20
109
1.91
1.83
1.4
1.2
—
—
—
0
0
34
218
1.65
1.82
10.1
9.8
9.30
9.84
mmol/l
0.21
34
210
219
2023
1.57
1.77
4.7
4.1
1.54
1.40
mmol/l
1.50
199
1901
7
24
2.97
1.73
1.3
1.6
—
—
—
0
0
21
119
1.83
1.72
2.1
4.0
—
—
—
0
0
25
150
1.74
1.71
1.6
1.5
—
—
—
0
0
182
1629
1.41
1.68
5.2
3.4
43.33
56.49
u/l
3.36
174
1570
8
31
2.63
1.67
1.5
1.4
12.50
11.27
%
—
8
31
7
25
2.85
1.66
1.3
2.1
13.14
11.08
mmol/l
—
7
25
5
14
3.62
1.62
1.8
1.0
1548.50
1335.79
miu/ml
—
5
14
41
284
1.53
1.61
3.0
2.8
25.97
23.79
%
0.35
35
276
7
26
2.74
1.59
1.7
1.1
—
—
—
0
0
43
303
1.50
1.56
3.4
2.8
0.24
0.43
e6/l
0.63
25
151
46
329
1.49
1.56
3.1
2.8
14.16
13.42
umol/l
0.27
41
312
212
1960
1.47
1.55
6.2
4.7
6.24
6.03
mmol/l
0.97
190
1825
65
498
1.41
1.54
1.7
1.7
17.27
18.15
nmol/l
0.18
51
432
33
223
1.55
1.45
11.6
16.1
131.79
125.03
g/l
0.84
33
215
65
503
1.39
1.45
3.5
3.0
0.14
0.54
e6/l
1.68
47
367
16
88
1.87
1.45
3.5
1.9
0.58
1.19
ug/l
0.47
16
76
5
16
3.17
1.44
1.2
1.8
233.00
145.81
e6/l
—
5
16
5
16
3.17
1.44
1.2
1.3
—
—
—
0
0
43
309
1.47
1.43
3.4
2.8
2.28
2.27
g/l
0.03
37
291
13
67
1.99
1.41
1.4
1.2
—
—
—
0
0
7
29
2.45
1.40
1.6
1.8
21.41
30.83
g/l
—
7
24
10
47
2.17
1.35
9.1
16.8
11.90
12.45
mmol/l
—
10
40
10
47
2.17
1.35
9.1
16.8
104.80
105.30
mmol/l
—
10
40
20
121
1.71
1.35
6.5
2.1
—
—
—
0
0
53
403
1.40
1.31
3.6
3.0
—
0.00
—
0
6
8
34
2.40
1.30
3.4
6.9
—
—
—
0
0
5
18
2.81
1.29
1.0
1.1
—
—
—
0
0
47
351
1.42
1.28
2.8
2.7
623.47
584.80
mosm/kgh2o
0.54
41
298
30
205
1.52
1.27
11.8
15.1
—
—
—
0
0
14
78
1.84
1.23
1.1
1.2
—
—
—
0
0
8
38
2.14
1.19
1.0
1.3
—
—
—
0
0
6
26
2.34
1.19
1.7
1.2
—
—
—
0
0
11
57
1.97
1.19
10.7
3.0
—
—
—
0
0
66
531
1.33
1.14
6.7
5.2
7.40
7.40
ph
0.78
50
379
8
40
2.03
1.13
1.9
1.8
—
—
—
0
0
28
194
1.50
1.12
3.6
2.4
29.21
35.28
u/l
0.95
28
162
15
89
1.73
1.10
1.3
2.1
1.51
1.53
g/l
0.05
15
82
5
21
2.41
1.09
2.2
1.2
—
—
—
0
0
7
33
2.15
1.06
1.1
1.2
160.29
185.68
pmol/l
—
7
33
7
33
2.15
1.06
1.4
1.1
—
—
—
0
0
5
22
2.30
1.04
2.6
2.3
30.02
35.34
%
—
5
22
5
22
2.30
1.04
2.0
4.0
482.60
1575.00
mg
—
5
22
12
71
1.72
0.90
4.6
4.9
858.00
264.33
mg/l
—
7
48
11
64
1.75
0.87
3.2
4.2
64.54
62.02
%
0.14
11
64
14
89
1.61
0.83
1.9
1.2
—
—
—
0
0
6
33
1.84
0.79
3.3
3.3
—
—
—
0
0
87
758
1.22
0.78
3.3
2.4
0.70
0.73
ug/l
0.15
53
401
6
34
1.78
0.77
1.2
1.3
—
—
—
0
0
5
25
2.02
0.73
2.4
3.2
107.20
106.04
mmol/l
—
5
25
5
25
2.02
0.73
2.4
3.2
1.20
1.20
mmol/l
—
5
25
5
25
2.02
0.73
2.6
3.8
—
—
—
0
0
5
25
2.02
0.73
2.4
3.2
4.12
4.19
mmol/l
—
5
25
5
26
1.94
0.71
1.2
1.0
—
2.23
—
0
12
9
58
1.57
0.70
3.4
6.3
27.70
50.48
mg/l
—
9
52
9
58
1.57
0.70
3.4
6.3
25.81
34.33
mg/l
—
9
53
44
359
1.27
0.70
1.7
1.7
224324704.38
409.55
pmol/l
0.49
37
316
22
162
1.39
0.69
6.0
2.1
—
—
—
0
0
5
27
1.87
0.69
1.0
1.2
190.60
266.64
pmol/l
—
5
22
5
27
1.87
0.69
2.0
1.4
0.67
0.56
e9/l
—
5
27
13
86
1.54
0.67
1.1
1.3
309.83
83.13
u/ml
—
6
33
22
163
1.38
0.67
6.1
2.1
—
—
—
0
0
22
163
1.38
0.67
5.9
2.1
—
—
—
0
0
22
163
1.38
0.67
4.5
2.1
—
—
—
0
0
19
138
1.41
0.64
5.5
8.1
—
—
—
0
0
10
63
1.61
0.62
1.1
1.1
—
—
—
0
0
20
148
1.38
0.62
6.5
2.1
—
—
—
0
0
13
88
1.50
0.62
1.6
1.5
—
—
—
0
0
5
30
1.68
0.61
1.0
1.1
—
—
—
0
0
23
175
1.35
0.60
2.7
4.9
0.90
1.07
%
—
10
59
22
167
1.35
0.59
2.7
5.0
0.22
0.16
%
—
9
50
66
577
1.19
0.57
9.2
6.4
—
—
—
0
0
12
82
1.49
0.55
1.1
1.3
—
—
—
0
0
21
161
1.33
0.53
3.3
5.6
0.00
0.07
%
—
8
41
53
462
1.19
0.47
3.8
4.9
—
—
—
0
0
7
48
1.47
0.47
1.9
2.3
8.80
7.94
kpa
—
7
48
21
165
1.30
0.46
3.1
4.7
0.80
0.52
%
—
10
53
25
204
1.25
0.42
1.4
1.3
—
—
—
0
0
5
32
1.57
0.42
3.8
2.3
0.72
0.64
nmol/l
—
5
26
0
15
0.00
0.41
0.0
2.2
—
513.33
—
0
9
0
16
0.00
0.41
0.0
5.6
—
8.15
—
0
16
10
71
1.43
0.40
8.5
12.1
—
—
—
0
0
5
35
1.44
0.39
4.6
4.1
6.36
8.12
mmol/l
—
5
35
0
19
0.00
0.39
0.0
2.2
—
511.60
—
0
10
5
36
1.40
0.38
1.2
1.8
—
—
—
0
0
5
36
1.40
0.38
1.2
1.8
—
—
—
0
0
5
36
1.40
0.38
1.2
1.8
—
—
—
0
0
5
36
1.40
0.38
1.2
1.8
—
—
—
0
0
37
321
1.18
0.36
3.5
3.1
2.45
2.44
mmol/l
0.14
32
289
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
11
85
1.31
0.28
1.3
3.9
4.22
4.59
pmol/l
—
6
78
14
114
1.24
0.25
2.1
3.2
—
—
—
0
0
5
39
1.29
0.23
1.8
4.1
—
—
—
0
0
85
898
0.92
0.23
11.7
11.5
0.00
0.00
e9/l
0.45
64
734
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
28.50
—
0
10
0
10
0.00
0.21
0.0
1.3
—
8.14
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
7.8
—
0.62
—
0
13
0
14
0.00
0.20
0.0
5.9
—
18.81
—
0
14
11
132
0.83
0.18
1.1
1.1
1.36
1.42
g/l
0.46
11
132
7
58
1.21
0.18
1.3
1.2
—
—
—
0
0
7
59
1.19
0.18
1.3
1.2
—
—
—
0
0
10
83
1.21
0.15
1.5
1.5
—
—
—
0
0
29
316
0.91
0.15
1.2
1.4
—
—
—
0
0
11
127
0.86
0.12
1.1
1.1
—
0.67
—
0
13
17
154
1.11
0.10
2.5
1.7
0.20
0.35
mg/l
—
10
82
188
1855
1.05
0.10
25.0
18.9
335.97
335.75
g/l
0.12
188
1849
5
47
1.07
0.09
4.2
1.5
—
—
—
0
0
6
55
1.09
0.09
4.3
6.1
1.28
1.58
ratio
—
6
29
12
133
0.90
0.08
1.6
1.1
0.96
0.93
g/l
0.17
12
133
6
74
0.81
0.07
1.3
1.1
—
—
—
0
0
16
147
1.09
0.07
1.1
1.1
—
—
—
0
0
22
206
1.07
0.07
1.3
1.2
—
—
—
0
0
28
266
1.06
0.06
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
3907.17
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
10.89
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
69.33
—
0
6
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
0.20
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
62.12
—
0
6
0
5
0.00
-0.00
0.0
2.4
—
11.38
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
0.45
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
49.58
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_MALEGENINOTH and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_MALEGENINOTH 1.305 [1.07, 1.59] 0.008
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 156 out of 1765 males with N14_MALEGENINOTH died.

Mortality risk

Mortality risk for people of age

years, who have N14_MALEGENINOTH.

N-year risk Females Males
1 No data 0.236%
5 No data 1.558%
10 No data 3.758%
15 No data 7.027%
20 No data 11.796%

Relationships between endpoints

Index endpoint: N14_MALEGENINOTH – Disorders of male genital organs in diseases classified elsewhere

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data