Hemoglobin A1c/Hemoglobin.total in Blood

    
          Number of people
          
370 260 (57.49% female)
          
          People with ≥2 records
          75.89%

          Median duration from first to last measurement
          4.51 years

Coding

Definition

OMOP Concept ID: 3004410— open in OHDSI Athena.
Part of collection: Hemoglobin A1c/Hemoglobin.total with 0 other OMOP concept — open in OHDSI Athena.

OMOP mapping QC

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3004410	b-hba1c	mmol/mol (mmol/mol)	340811	1304652	0.01%
3004410	b-hba1c	— (—)	107885	431333	100.00%	Distribution not available
3004410	b-ghb-a1c	— (—)	28857	51164	100.00%	Distribution not available
3004410	b-ghb-a1c	% (mmol/mol)	28124	48158	0.00%
3004410	b-hb-a1c	% (mmol/mol)	26776	43499	0.00%
3004410	b-hb-a1c	— (—)	11544	20231	100.00%	Distribution not available
3004410	b-hb-a1c	mmol/mol (mmol/mol)	3449	7501	0.00%
3004410	b-hemoglobiini-a1c	mmol/mol (mmol/mol)	3448	4557	0.00%
3004410	b-hba1c,tk	— (—)	2652	7614	100.00%	Distribution not available
3004410	b-ghba1c	% (mmol/mol)	2427	3608	0.00%
3004410	b-ghb-a1c,tk	— (—)	2204	5108	100.00%	Distribution not available
3004410	b-hba1cp	mmol/mol (mmol/mol)	2125	12825	0.00%
3004410	b-hba1c,t	— (—)	2056	10368	100.00%	Distribution not available
3004410	b-hba1cvt	mmol/mol (mmol/mol)	1808	9177	0.00%
3004410	b-hba1cvt	% (mmol/mol)	1160	7267	0.00%
3004410	b-ghba1cp	— (—)	936	3999	100.00%	Distribution not available
3004410	b-ghb-a1c	mmol/mol (mmol/mol)	863	2058	0.00%
3004410	b-hba1cvt	— (—)	799	3408	100.00%	Distribution not available
3004410	hemoglobiini-a1c,glykoitunut(b-hba1c)	mmol/mol (mmol/mol)	797	1455	0.00%
3004410	b-hba1cp	% (mmol/mol)	696	1571	0.00%
3004410	b-hba1c/pika	— (—)	594	1278	100.00%	Distribution not available
3004410	b-hba1c	% (mmol/mol)	562	776	0.00%
3004410	hemoglobiini-a1c,glykoitunut(6128b-hba1c)	mmol/mol (mmol/mol)	522	754	0.00%
3004410	b-ghba1cp	% (mmol/mol)	487	887	0.00%
3004410	b-hba1c/p	— (—)	392	1078	100.00%	Distribution not available
3004410	b-ghba1c/pika	% (mmol/mol)	357	722	0.00%
3004410	hba1cvieri	— (—)	349	882	100.00%	Distribution not available
3004410	b-vthba1c	mmol/mol (mmol/mol)	346	1184	0.00%
3004410	b-hba1c-p	mmol/mol (mmol/mol)	329	864	0.00%
3004410	b-hba1cpi	mmol/mol (mmol/mol)	302	1256	0.00%
3004410	ghb-a1c(vo.hoitaja)	mmol/mol (mmol/mol)	224	431	0.00%
3004410	b-ghba1c/p	% (mmol/mol)	221	506	0.00%
3004410	hba1cvieri	mmol/mol (mmol/mol)	216	430	0.00%
3004410	hba1c-pika	— (—)	201	1288	100.00%	Distribution not available
3004410	pika-hba1c	— (—)	194	435	100.00%	Distribution not available
3004410	b-hba1c/pika	mmol/mol (mmol/mol)	184	455	0.00%
3004410	b-hba1c/p	mmol/mol (mmol/mol)	179	568	0.00%
3004410	b-ghba1c/	% (mmol/mol)	179	566	0.00%
3004410	ghb-a1c(vo.hoitaja)	— (—)	147	232	100.00%	Distribution not available
3004410	b-ghb-a1cv	mmol/mol (mmol/mol)	137	338	0.00%
3004410	b-ghba1c/p	— (—)	134	206	100.00%	Distribution not available
3004410	b-hemoglobiini-a1c	— (—)	107	139	100.00%	Distribution not available
3004410	b-hba1c-p	% (mmol/mol)	99	148	0.00%
3004410	b-ghba1c-oma	% (mmol/mol)	85	360	0.00%
3004410	pika-ghb-a1c,pika-ghb-a1c	% (mmol/mol)	78	301	0.00%
3004410	pika-ghb-a1c,pika-hba1c	mmol/mol (mmol/mol)	78	297	0.00%
3004410	b-hba1chy	mmol/mol (mmol/mol)	73	261	0.00%
3004410	b-ghba1c/pika	— (—)	73	131	100.00%	Distribution not available
3004410	hba1c-vieri	mmol/mol (mmol/mol)	65	111	0.00%
3004410	pika-ghb-a,pika-ghb-a1c	% (mmol/mol)	64	216	0.00%
3004410	pika-ghb-a,pika-hba1c	mmol/mol (mmol/mol)	64	216	0.00%
3004410	hba1c-vier	mmol/mol (mmol/mol)	62	100	0.00%
3004410	b-hba1c-e	mmol/mol (mmol/mol)	61	85	0.00%
3004410	b-hba1cp	— (—)	58	63	100.00%	Distribution not available
3004410	b-hba1c-p	— (—)	55	63	100.00%	Distribution not available
3004410	cb-hba1cnla	mmol/mol (mmol/mol)	51	211	0.00%
3004410	b-ghbpika	— (—)	51	142	100.00%	Distribution not available
3004410	b-ghba1c-	% (mmol/mol)	47	123	0.00%
3004410	cb-hba1chy	mmol/mol (mmol/mol)	35	51	0.00%
3004410	b-ghba1c	— (—)	33	36	100.00%	Distribution not available
3004410	hemoglobiini-a1c,glykoitunut(b-hba1c)	— (—)	31	32	100.00%	Distribution not available
3004410	ghb-a1c-pika	% (mmol/mol)	30	89	0.00%
3004410	cb-hba1cnla	— (—)	26	102	100.00%	Distribution not available
3004410	pika-hba1c	mmol/mol (mmol/mol)	25	38	0.00%
3004410	b-ghba1c-o	— (—)	25	62	100.00%	Distribution not available
3004410	pika-ghb-a	mmol/mol (mmol/mol)	16	24	0.00%
3004410	b-ghba1c-oma	— (—)	12	13	100.00%	Distribution not available
3004410	b-ghba1c/	— (—)	10	11	100.00%	Distribution not available
3004410	cb-hba1c	mmol/mol (mmol/mol)	8	29	0.00%	Distribution not available
3004410	b-vthba1c	— (—)	7	7	100.00%	Distribution not available
3004410	cb-ghb-a1c	% (mmol/mol)	7	21	0.00%	Distribution not available
3004410	b-ehba1c	mmol/mol (mmol/mol)	6	7	0.00%	Distribution not available	Distribution not available
3004410	b-ghb-a1cv	— (—)	5	5	100.00%	Distribution not available	Distribution not available

Cohort

Number of people: 370 260 (57.49% female)

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

People with ≥2 records: 75.89%
Median number of measurements per person: 3.0
Median duration from first to last measurement: 4.51 years

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Sciatica+with lumbago

23321

193976

1.94

323.01

6.3

5.3

39.83

39.40

mmol/mol

10.47

22078

179808

Other arrhythmias

30132

204407

1.73

322.35

6.3

5.3

39.64

39.18

mmol/mol

13.93

27967

189350

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

12649

132317

0.55

318.51

5.9

6.3

41.32

40.42

mmol/mol

17.13

11307

121765

Injuries to the knee and lower leg

58614

306557

1.43

315.01

5.8

5.3

39.65

39.21

mmol/mol

22.01

54724

285106

Excessive, frequent and irregular menstruation

18537

86800

1.89

311.79

5.5

4.5

38.61

38.22

mmol/mol

6.66

17180

80776

Other headache syndromes

19019

163740

1.98

309.40

5.9

4.9

38.96

38.76

mmol/mol

2.39

17918

151949

Other disorders of urethra and urinary system

31929

211720

1.61

308.86

6.6

5.3

40.28

39.14

mmol/mol

71.77

29566

195697

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

46382

277656

1.69

307.65

7.3

5.1

41.07

39.06

mmol/mol

298.23

42939

258455

Spondylosis

24200

181891

2.00

307.65

6.7

5.7

40.25

39.98

mmol/mol

4.48

22649

167348

Type 2 diabetes

54277

253680

3.60

307.65

11.8

3.5

48.77

36.49

mmol/mol

307.65

51494

234447

Abnormalities of breathing

48188

239134

2.01

307.65

6.5

4.8

40.26

38.82

mmol/mol

166.23

45147

222683

Coxarthrosis [arthrosis of hip](FG)

24826

156336

1.92

307.65

6.8

5.8

40.28

40.32

mmol/mol

0.22

23140

142658

Meniscus derangement

27467

164139

1.93

307.65

6.1

5.4

39.85

39.87

mmol/mol

0.15

25519

151749

Gonarthrosis,primary

42917

234336

2.15

307.65

6.9

5.8

40.41

40.13

mmol/mol

7.71

40106

215926

Dental caries 3, only avohilmo

44704

193781

1.94

307.65

5.9

5.3

39.89

39.43

mmol/mol

18.33

41369

179462

Hypothyreosis and Thyroxine purchase for inclusion criteria

45804

260047

1.94

307.65

6.5

5.3

40.04

39.15

mmol/mol

63.40

42438

241458

Sensorineural hearing loss

33869

211251

1.69

307.65

6.9

5.9

40.57

40.16

mmol/mol

12.81

30580

194829

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

53139

252246

3.92

307.65

13.0

3.5

51.55

36.49

mmol/mol

307.65

50391

233070

Dorsalgia

52927

246733

1.78

307.65

6.0

5.1

39.57

39.11

mmol/mol

21.93

49580

229095

Hypertension, essential

41465

193746

2.69

307.65

7.9

4.3

42.42

38.14

mmol/mol

307.65

39320

179830

Diseases of the ear and mastoid process

60965

278731

1.46

307.65

5.8

5.1

39.39

39.15

mmol/mol

8.09

56442

260674

Anaemias

11339

55752

2.67

307.65

7.1

2.3

40.24

35.70

mmol/mol

321.10

10690

52778

Other disorders of ear

43756

259503

1.66

307.65

6.5

5.6

40.03

39.71

mmol/mol

10.70

39903

241158

Hypothyroidism, strict autoimmune, 3 medication purchases required

41530

242781

1.99

307.65

6.6

5.2

40.12

39.08

mmol/mol

76.64

38315

225385

Diverticular disease of intestine

33401

196606

1.79

307.65

7.1

5.7

40.47

40.12

mmol/mol

10.06

30955

181156

Coxibs

14591

57751

2.43

307.65

5.7

5.2

39.26

39.58

mmol/mol

3.42

13577

53213

Other arthrosis

24789

153184

2.09

307.65

6.5

5.5

39.89

40.02

mmol/mol

1.43

23231

141257

Dental caries 1, only avohilmo

42406

182753

1.99

307.65

5.9

5.4

39.95

39.53

mmol/mol

14.16

39254

169068

Insulin, intermediate and long-acting

25714

200937

4.23

307.65

15.9

5.0

60.62

38.23

mmol/mol

307.65

24447

185097

Type 1 diabetes, strict definition

3790

23380

18.56

307.65

13.7

2.5

61.50

34.85

mmol/mol

307.65

3651

22319

Dental caries 1

41643

179606

1.95

307.65

6.0

5.3

39.96

39.50

mmol/mol

16.89

38554

166105

Coxarthrosis

23295

134945

2.04

307.65

6.8

5.7

40.25

40.34

mmol/mol

0.85

21725

123475

Gastro-oesophageal reflux disease

31816

247110

1.95

307.65

6.8

5.5

40.01

39.60

mmol/mol

11.79

29161

229155

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

4540

56517

0.37

307.65

5.8

6.8

41.42

41.12

mmol/mol

1.16

3978

51476

Examination and observation for other reasons

30685

158304

1.85

307.65

6.1

4.6

39.45

38.76

mmol/mol

26.24

29022

146863

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

5464

65993

0.38

307.65

5.8

6.7

41.19

41.03

mmol/mol

0.53

4821

60162

Used for control exclusion in common control thyroid runs

56141

250953

1.58

307.65

6.7

4.8

41.44

38.47

mmol/mol

307.65

52486

233545

Sleep apnoea

47501

264749

3.47

307.65

7.8

5.2

41.50

39.31

mmol/mol

307.65

44522

246040

General symptoms and signs

58138

263797

1.45

307.65

6.0

5.1

39.63

39.05

mmol/mol

33.61

54400

245624

Oter anti-inflammatory and antirheumatic agents, non-steroids

10641

45355

2.35

307.65

6.7

5.8

40.47

40.67

mmol/mol

1.33

9781

41431

Other (not insulin) diabetes medications

52266

250178

3.51

307.65

12.0

3.7

48.56

36.69

mmol/mol

307.65

49480

230982

Diseases of pulp and periapical tissues, including avohilmo

57315

258876

1.75

307.65

5.9

5.2

39.89

39.04

mmol/mol

72.48

53166

240686

Hypertensive diseases

42764

198349

2.60

307.65

7.9

4.3

42.28

38.09

mmol/mol

307.65

40624

184251

Obesity due to excess calories

21235

171010

3.80

307.65

9.6

4.9

43.27

38.64

mmol/mol

307.65

20179

159691

Other nutritional deficiencies

30791

246157

3.09

307.65

8.9

4.9

42.60

38.67

mmol/mol

307.65

29264

229726

Parodontitis

43187

281549

1.93

307.65

6.7

5.5

40.48

39.59

mmol/mol

63.07

39768

262049

Pain in limb

38836

235362

2.14

307.65

6.5

5.1

40.14

39.06

mmol/mol

84.26

36315

218393

Gonarthrosis

33457

162114

2.16

307.65

6.6

5.5

40.26

39.98

mmol/mol

5.73

31388

149603

Diseases of the skin and subcutaneous tissue

54445

246542

1.44

307.65

6.1

5.0

39.95

39.01

mmol/mol

77.29

50740

229325

Hypothyroidism, levothyroxine purchases

14971

60944

3.18

307.65

5.9

2.3

39.37

35.57

mmol/mol

307.65

14140

57773

Lumbar disc prolapse

30604

215064

1.82

307.65

6.2

5.3

39.89

39.44

mmol/mol

13.44

28895

199577

Obesity

29356

237341

3.23

307.65

9.1

4.9

42.86

38.67

mmol/mol

307.65

27939

221586

Hypothyroidism and >3 levothyroxin purchases

14971

60944

3.18

307.65

5.9

2.3

39.37

35.57

mmol/mol

307.65

14140

57773

Persons encountering health services for other counselling and medical advice, not elsewhere classified

56545

287880

1.59

307.65

6.1

5.2

39.99

39.16

mmol/mol

69.44

53540

267110

Disorders of choroid and retina

36142

233400

1.74

307.65

8.5

5.7

44.75

39.62

mmol/mol

307.65

32971

215261

Insulin medication

27734

193238

2.48

307.65

15.6

3.7

59.74

36.72

mmol/mol

307.65

26354

177539

Insulin, fast-acting

16269

128197

4.10

307.65

16.2

4.8

62.48

37.88

mmol/mol

307.65

15567

118649

Chronic periodontitis, including avohilmo

42977

281440

1.92

307.65

6.7

5.5

40.48

39.59

mmol/mol

62.95

39576

261945

Other special examinations and investigations of persons without complaint or reported diagnosis

37851

159997

1.89

307.65

6.4

4.6

40.51

38.77

mmol/mol

165.37

35607

148372

Medical observation and evaluation for suspected diseases and conditions

37017

159984

1.81

307.65

6.5

4.6

39.85

38.77

mmol/mol

72.85

34171

148363

Dental operations, only avohilmo

37242

157571

2.16

307.65

6.0

5.4

39.92

39.85

mmol/mol

0.62

34531

145206

Hypertension

42753

198222

2.61

307.65

7.9

4.3

42.28

38.10

mmol/mol

307.65

40613

184131

Dental caries, including avohilmo

41604

179473

1.95

307.65

6.0

5.3

39.97

39.50

mmol/mol

17.30

38516

165971

Artificial joint operation, meniscal resection

43634

256426

1.90

307.65

6.4

5.8

39.97

40.01

mmol/mol

0.51

40702

237074

Dental caries 3

43981

190845

1.91

307.65

5.9

5.3

39.92

39.40

mmol/mol

22.90

40699

176703

Diabetes mellitus

58027

266970

3.92

307.65

11.9

3.5

49.55

36.34

mmol/mol

307.65

55116

247080

ILD medications: prednisolone, methylprednisolone, prednisone

55706

284868

1.47

307.65

6.3

5.2

39.63

39.25

mmol/mol

15.92

52145

264771

Other joint disorders

46985

216547

1.67

307.65

5.4

4.9

38.91

38.96

mmol/mol

0.55

43962

201484

Selective serotonin reuptake inhibitors

53560

247357

1.63

307.65

6.1

5.1

39.46

39.31

mmol/mol

2.82

49582

230476

Combinations of oral blood glucose lowering drugs

11898

95297

7.88

307.65

14.6

4.3

53.84

37.63

mmol/mol

307.65

11343

87130

Benign neoplasms

50323

252233

1.47

307.65

5.9

5.0

39.53

39.12

mmol/mol

16.86

47004

235469

Codeine

52860

243580

2.17

307.65

6.2

4.9

40.04

38.83

mmol/mol

133.14

49595

226537

Parasetamol

46209

191295

2.08

307.65

5.9

4.5

39.66

38.49

mmol/mol

108.89

43392

178318

Other intervertebral disc disorders

43106

227467

1.94

307.65

6.3

5.3

39.90

39.41

mmol/mol

21.12

40548

210909

Rotator cuff syndrome

29493

191391

2.07

307.65

6.7

5.5

40.54

39.75

mmol/mol

40.37

27890

176765

Shoulder lesions

39552

208552

2.12

307.65

6.7

5.4

40.75

39.55

mmol/mol

107.90

37241

193050

Finngen Rheumatological endpoints

50737

252623

1.69

307.65

6.0

5.0

39.43

39.15

mmol/mol

8.32

47769

234818

Type 2 diabetes, wide definition

38753

210433

2.51

307.65

13.3

3.9

50.99

37.13

mmol/mol

307.65

36769

193117

General examination and investigation of persons without complaint and reported diagnosis

35054

159800

1.73

307.65

5.9

4.6

39.85

38.77

mmol/mol

74.39

32934

148229

Pain (limb, back, neck, head abdominally)

40363

178600

1.52

307.65

5.7

5.0

39.56

39.22

mmol/mol

9.00

37678

165585

Mood [affective] disorders

51200

300204

1.61

307.65

6.2

5.2

39.36

39.19

mmol/mol

3.40

47764

279867

Headache

31788

234304

1.67

307.65

5.8

5.0

38.95

38.88

mmol/mol

0.63

29872

218226

Dental pulpitis 4, only avohilmo

58335

264678

1.78

307.65

5.9

5.2

39.85

39.08

mmol/mol

63.31

54167

246064

Persons encountering health services for specific procedures and health care

53649

297065

1.55

307.65

6.7

5.1

40.47

39.06

mmol/mol

180.36

50216

276320

Arthropathies

48095

216823

1.51

307.65

5.5

4.9

39.08

38.96

mmol/mol

1.74

45151

201746

Persons encountering health services in other circumstances, wide

62873

289569

1.60

307.65

6.1

5.2

40.10

39.18

mmol/mol

91.04

59163

268554

Other dorsopathies, not elsewhere classified

54328

247560

1.75

307.65

5.8

5.1

39.37

39.10

mmol/mol

8.55

50984

229884

Dental caries 3 and operation codes

48266

210798

1.93

307.65

6.0

5.3

39.78

39.42

mmol/mol

12.98

44822

195381

Dorsopathies

54583

248321

1.51

307.65

5.7

5.1

39.29

39.09

mmol/mol

4.85

51145

230595

Diabetes, insulin treatment (Kela reimbursement)

55268

266488

3.62

307.65

13.0

3.8

51.50

36.78

mmol/mol

307.65

52362

246399

Mood disorders

51318

300474

1.61

307.65

6.2

5.2

39.37

39.19

mmol/mol

3.60

47870

280112

Pure hypercholesterolaemia

35755

199918

2.93

307.65

8.5

5.5

43.19

39.59

mmol/mol

307.65

33650

183421

Inflammatory bowel disease treatment related agents

57759

298251

1.44

307.65

6.1

5.2

39.53

39.24

mmol/mol

10.13

54162

277179

Antihypertensive medication - note that there are other indications

34730

141076

2.79

307.65

5.8

3.2

39.71

36.58

mmol/mol

307.65

32972

132011

Pain in throat and chest

45597

229898

2.23

307.65

6.6

4.9

40.21

38.96

mmol/mol

126.97

42659

213961

Endocrine, nutritional and metabolic diseases

48378

188422

2.68

307.65

7.4

2.9

42.62

35.95

mmol/mol

307.65

45740

175032

Lung cancer and mesothelioma

4625

56578

0.37

307.65

5.8

6.4

41.35

40.44

mmol/mol

8.07

4055

51205

Dizziness and giddiness

34347

245403

1.76

307.65

6.7

5.6

40.15

39.61

mmol/mol

21.82

31828

226791

Persons encountering health services for examination and investigation

36656

160000

1.58

307.65

5.9

4.6

39.94

38.77

mmol/mol

78.97

34312

148374

785

20745

0.16

307.65

5.5

6.4

41.68

41.00

mmol/mol

0.70

658

19016

Type1 diabetes, definitions combined, early onset

2974

18314

13.94

307.65

13.6

3.4

61.02

36.28

mmol/mol

307.65

2867

17501

Depression

47274

290121

1.62

307.65

6.2

5.1

39.29

39.10

mmol/mol

3.46

44122

270875

Disorders of thyroid, IBD co-morbidities

9003

48273

2.93

307.65

6.0

2.7

39.60

36.02

mmol/mol

214.38

8441

44671

Diseases of the eye and adnexa

44620

198165

1.50

307.65

5.8

4.5

39.92

38.30

mmol/mol

180.83

41861

186289

Malignant neoplasm of respiratory system and intrathoracic organs

4105

58069

0.39

307.65

5.5

6.7

41.29

41.21

mmol/mol

0.20

3574

52369

Hypothyroidism, drug reimbursement

7386

39105

3.19

307.65

6.6

2.5

40.43

35.98

mmol/mol

223.69

6955

36766

Cardiovascular diseases

33394

149572

1.97

307.65

5.5

3.5

39.16

37.15

mmol/mol

224.44

31751

140316

Lower back pain or/and sciatica

51343

310951

1.82

307.65

6.2

5.3

39.67

39.30

mmol/mol

15.63

48159

288937

Episodal and paroxysmal disorders

60659

262480

1.91

307.65

6.3

4.9

39.77

38.92

mmol/mol

79.29

56936

243446

Nerve, nerve root and plexus disorders

53391

292190

1.86

307.65

7.1

5.3

41.44

39.19

mmol/mol

307.65

50227

270962

Neurological diseases, wide definition

17556

66245

2.23

307.65

5.3

2.5

38.85

35.58

mmol/mol

311.93

16572

61783

Opioids

53578

246709

1.64

307.65

6.0

4.9

39.83

38.79

mmol/mol

97.39

50191

229435

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

10657

83506

78.73

307.65

15.9

4.0

55.00

37.35

mmol/mol

307.65

10260

77398

Oxicams

11646

50417

2.38

307.65

6.3

5.5

40.11

40.20

mmol/mol

0.40

10817

46242

Type 2 diabetes, definitions combined, including avohilmo

52106

242805

3.66

307.65

11.1

3.5

46.99

36.51

mmol/mol

307.65

49332

224189

Atrial fibrillation and flutter with reimbursement

12808

66957

3.50

307.65

7.4

4.4

41.43

38.43

mmol/mol

230.26

12023

60824

ILD medications

57974

288977

1.44

307.65

6.2

5.1

39.47

39.20

mmol/mol

9.16

54294

268662

Other diseases of hard tissues of teeth

30809

203260

1.72

307.65

6.0

5.1

38.73

39.23

mmol/mol

19.89

28666

189604

Disorders of the thyroid gland

47382

267993

1.85

307.65

6.4

5.3

39.99

39.21

mmol/mol

50.84

44009

248867

Asthma, including avohilmo

59165

308000

1.53

307.65

5.9

5.3

39.68

39.22

mmol/mol

25.10

55708

285935

Symptoms and signs involving the circulatory and respiratory systems

55456

240494

1.69

307.65

5.9

4.8

39.50

38.80

mmol/mol

47.48

52005

223993

Artrosis, including avohilmo

44315

207166

1.97

307.65

6.1

5.2

39.84

39.56

mmol/mol

7.21

41562

192357

Sleep apnoea, including avohilmo

51023

269880

3.52

307.65

7.5

5.2

41.19

39.23

mmol/mol

307.65

47883

250857

Dental pulpitis 1

57407

259251

1.76

307.65

5.9

5.2

39.89

39.04

mmol/mol

72.03

53246

241045

Complications of surgical and medical care, not elsewhere classified

46540

299888

1.58

307.65

6.6

5.4

40.28

39.38

mmol/mol

67.37

43434

278405

Gingivitis and periodontal diseases

48405

216052

1.82

307.65

6.0

5.2

39.63

39.43

mmol/mol

4.53

44889

200745

Dyspnoea

41264

282266

1.63

307.65

7.1

5.4

40.99

39.42

mmol/mol

169.57

38330

261576

Insulin, combination of fast acting with intermediate-acting or long-acting

27773

216163

2.17

307.65

15.6

5.0

59.75

38.20

mmol/mol

307.65

26387

199063

Autoimmune diseases

58399

265062

1.54

307.65

6.9

4.8

41.75

38.49

mmol/mol

307.65

54550

246695

Obesity, other/unspecified

14808

120147

3.28

307.65

8.9

4.7

42.18

38.53

mmol/mol

282.40

14242

112578

Other antidepressants

56257

246815

2.03

307.65

6.2

5.1

39.51

39.31

mmol/mol

4.69

52088

229975

Mood disorders, excluding more controls

48281

260385

1.66

307.65

6.4

5.1

39.54

39.17

mmol/mol

12.57

45013

243057

Oral corticosteroids

52854

289740

1.48

307.65

6.2

5.3

39.83

39.34

mmol/mol

25.62

49506

269094

Hyperlipidaemia, other/unspecified

16305

130076

2.80

307.65

9.5

5.9

43.94

40.00

mmol/mol

307.65

15099

117983

Dental caries 1 and operation codes

46288

201075

1.98

307.65

6.0

5.3

39.79

39.52

mmol/mol

7.55

42942

186224

Acetic acid derivatives and related substances

14048

57237

1.99

307.65

5.8

5.2

39.58

39.62

mmol/mol

0.14

13041

52731

Depression medications

17819

65222

2.62

307.65

5.0

2.2

38.08

35.48

mmol/mol

227.55

16760

61909

Pain in joint

30296

170709

1.95

307.65

5.8

5.0

39.05

39.14

mmol/mol

0.94

28490

158588

Biguanides

51310

250479

3.73

307.65

12.1

4.0

48.75

37.30

mmol/mol

307.65

48507

231247

Any reimbursement code in KELA

32795

138781

1.76

307.65

6.1

2.9

40.50

35.87

mmol/mol

307.65

31036

129709

Spondylopathies

39505

209438

1.81

307.65

6.7

5.4

40.33

39.71

mmol/mol

30.72

36911

193536

Type 1 diabetes, wide definition, subgroup 1

9824

70533

6.78

307.65

15.9

3.2

63.07

35.95

mmol/mol

307.65

9416

65780

Tramadol

40013

223368

1.84

307.65

7.0

5.1

40.84

39.16

mmol/mol

172.64

37422

207261

Type 1 diabetes, definitions combined

4554

29898

9.17

307.65

13.2

2.7

59.77

35.22

mmol/mol

307.65

4377

28291

Other soft tissue disorders, not elsewhere classified

47567

245237

2.11

307.65

6.3

5.0

39.89

38.98

mmol/mol

74.62

44457

227737

Type 1 diabetes, strict definition, subgroup 1

3629

21864

31.41

307.65

13.8

2.5

61.83

34.77

mmol/mol

307.65

3492

20874

Sleep disorders (combined)

52548

280644

3.12

307.65

7.5

5.1

41.03

39.09

mmol/mol

307.65

49266

261004

Glucagon-like peptide-1 (GLP-1) analogues

25545

164823

7.11

307.65

14.7

4.3

52.87

37.66

mmol/mol

307.65

23999

149862

Type 1 diabetes, strict (exclude DM2)

4517

29555

9.42

307.65

13.2

2.8

59.92

35.23

mmol/mol

307.65

4341

27960

Insulin, fast-acting or short human

16348

131284

3.24

307.65

16.2

5.1

62.44

38.54

mmol/mol

307.65

15642

121518

Hypertensive diseases (excluding secondary)

29836

136113

3.61

307.65

7.8

3.8

42.23

37.68

mmol/mol

307.65

28576

127118

Disorders of eyelid, lacrimal system and orbit

39163

272063

1.73

307.65

6.4

5.6

39.73

39.61

mmol/mol

1.75

36203

251966

Dental pulpitis 2, only avohilmo

38455

163917

2.02

307.65

5.9

5.4

39.98

39.51

mmol/mol

15.79

35530

151426

Diabetes medication

57734

271727

3.87

307.65

12.3

3.5

50.17

36.47

mmol/mol

307.65

54799

251519

Hypothyroidism, other/unspecified

44479

251772

1.96

307.65

6.5

5.2

40.04

39.14

mmol/mol

62.41

41236

233767

Dental pulpitis 1, only avohilmo

58448

265346

1.78

307.65

5.9

5.2

39.86

39.08

mmol/mol

64.10

54276

246699

Codeine or tramadol medication

61826

288863

2.17

307.65

6.4

5.2

40.18

39.13

mmol/mol

117.50

57949

268312

Obesity and other hyperalimentation

29494

238406

3.21

307.65

9.1

4.9

42.85

38.67

mmol/mol

307.65

28065

222574

Type 2 diabetes, definitions combined

51415

243341

3.52

307.65

11.3

3.6

47.27

36.59

mmol/mol

307.65

48693

224579

Other specific joint derangements/joint disorders

36822

210114

1.92

307.65

5.7

4.9

38.97

38.93

mmol/mol

0.37

34709

195698

Other retinal disorders

27040

188787

1.91

307.65

9.5

5.9

46.70

39.80

mmol/mol

307.65

24618

173140

Low back pain

36087

239013

1.88

307.65

6.1

5.1

39.60

39.17

mmol/mol

14.44

33751

221911

Parodontitis and operation codes

40496

278415

1.97

307.65

6.7

5.5

40.40

39.61

mmol/mol

47.38

37319

259125

Statin medication

39280

167353

3.41

307.65

7.8

3.7

43.14

37.24

mmol/mol

307.65

37287

155461

Symptoms and signs involving cognition, perception, emotional state and behaviour

46781

289686

1.70

307.65

6.5

5.4

40.05

39.41

mmol/mol

37.79

43380

269248

Dental pulpitis 4

57397

259186

1.76

307.65

5.9

5.2

39.89

39.04

mmol/mol

71.10

53234

240984

Disorders of lipoprotein metabolism and other lipidaemias

41907

218837

2.87

307.65

8.6

5.3

43.42

39.45

mmol/mol

307.65

39395

201542

Cardiac arrhythmias

31738

172518

2.28

307.65

6.0

3.1

39.52

36.06

mmol/mol

307.65

29898

160122

Carpal tunnel syndrome

27655

221450

1.93

307.65

7.2

5.4

41.51

39.31

mmol/mol

226.82

26142

204913

Other heart diseases, wide

46871

255580

1.73

307.65

6.3

5.0

40.08

38.87

mmol/mol

119.58

44015

238514

Gonarthrosis, primary, with knee surgery

24026

169044

2.52

307.65

7.3

6.2

40.59

40.50

mmol/mol

0.98

22319

153722

Other diseases of intestines

54391

279619

1.61

307.65

6.2

5.1

39.54

39.11

mmol/mol

19.35

50799

260623

Soft tissue disorders

55367

249350

1.68

307.65

5.9

5.0

39.67

38.95

mmol/mol

52.55

51785

231589

Recurrent or chronic depression

20654

122475

2.28

307.65

5.8

4.5

38.77

38.73

mmol/mol

0.17

19446

115441

Cardiovascular diseases (excluding rheumatic etc)

35197

165933

2.19

307.65

6.2

3.6

40.03

37.24

mmol/mol

307.65

33527

155471

Depression or dysthymia

37479

178215

1.92

307.65

6.2

5.2

39.69

39.41

mmol/mol

5.90

34659

166047

Type 1 diabetes, wide definition

10088

74932

4.12

307.65

15.8

3.3

62.82

36.01

mmol/mol

307.65

9667

69774

Malignant neoplasm of bronchus and lung

3373

49737

0.39

307.65

5.7

6.7

41.61

41.30

mmol/mol

0.94

2915

44746

Type 2 diabetes, strict (exclude DM1)

51543

244195

3.50

307.65

11.3

3.6

47.28

36.61

mmol/mol

307.65

48818

225379

Metabolic disorders

48515

254219

2.23

307.65

8.1

5.1

42.58

39.05

mmol/mol

307.65

45625

235418

Other heart diseases

24566

135241

2.14

307.65

6.4

3.8

40.21

37.65

mmol/mol

268.55

23280

126188

Dental pulpitis 2

37771

161049

2.00

307.65

5.9

5.3

39.98

39.50

mmol/mol

16.75

34906

148804

Conductive and sensorineural hearing loss

36096

223239

1.66

307.65

6.8

5.8

40.47

40.04

mmol/mol

14.75

32685

206307

Diseases of oral cavity, salivary glands and jaws

48706

217042

1.72

307.65

6.0

5.2

39.67

39.44

mmol/mol

5.41

45209

201559

Primary gonarthrosis, bilateral

21334

162989

2.23

307.65

7.2

6.1

40.71

40.40

mmol/mol

5.86

19811

148384

Parodontitis or operation codes

43235

281616

1.93

307.65

6.7

5.5

40.48

39.59

mmol/mol

63.47

39812

262112

Type 1 diabetes

11445

86901

3.41

307.65

15.4

3.3

61.26

36.09

mmol/mol

307.65

10965

80764

Gonarthrosis [arthrosis of knee](FG)

38933

196892

2.08

307.65

6.7

5.5

40.29

39.97

mmol/mol

8.53

36515

181630

Hypothyroidism (congenital or acquired)

15069

61191

3.19

307.65

5.9

2.3

39.43

35.57

mmol/mol

307.65

14235

58010

Diseases of oesophagus, stomach and duodenum

53060

287753

1.60

307.65

6.8

5.2

40.26

39.29

mmol/mol

88.41

49224

267882

Arthrosis

37486

177293

1.89

307.65

6.3

5.3

39.91

39.71

mmol/mol

3.44

35245

164185

Obesity related asthma

14223

119734

3.17

307.65

8.3

5.5

42.19

39.49

mmol/mol

164.09

13522

111123

Diabetes, varying definitions

57689

266244

3.88

307.65

11.9

3.5

49.46

36.39

mmol/mol

307.65

54784

246394

Dental operations

35293

148757

2.16

307.65

6.0

5.3

39.94

39.83

mmol/mol

1.27

32722

137022

Spinal stenosis

22454

152914

2.05

307.65

7.5

6.0

41.17

40.35

mmol/mol

31.23

20860

139266

Neurological diseases

48260

208167

1.72

307.65

5.9

4.6

39.63

38.48

mmol/mol

103.11

45300

193469

Atrial fibrillation and flutter

15755

86352

2.48

307.65

6.8

4.2

40.79

38.24

mmol/mol

181.21

14840

79389

Hypothyroidism, strict autoimmune

37778

212100

2.02

307.65

6.6

4.9

40.10

38.60

mmol/mol

144.82

34947

196532

Abnormalities of heart beat

15368

128133

2.10

307.54

6.5

5.2

39.69

39.22

mmol/mol

8.23

14173

117882

Cystitis

40692

222955

1.51

306.06

5.9

5.3

39.43

39.06

mmol/mol

10.80

37979

206214

Polycystic ovarian syndrome, consortium definition

32715

175615

1.64

304.39

5.9

4.8

39.07

38.28

mmol/mol

45.29

30206

163604

Diseases of the musculoskeletal system and connective tissue

30204

131226

1.54

301.53

5.2

4.4

38.90

38.55

mmol/mol

7.27

28386

122132

Autoimmune diseases excluding thyroid diseases

52403

263681

1.42

300.88

7.0

4.8

42.41

38.50

mmol/mol

307.65

49235

245427

Follow-up examination after treatment for conditions other than malignant neoplasms

22384

126443

1.75

297.95

5.7

4.6

39.24

38.62

mmol/mol

17.06

20950

116935

Anxiety disorders, excluding more controls

40801

244046

1.53

297.35

5.9

5.0

38.97

39.00

mmol/mol

0.32

38141

228385

Presence of other functional implants

24348

151390

1.80

295.03

7.9

6.0

42.49

40.15

mmol/mol

195.27

21656

137903

Cholecystectomy

31289

247828

1.68

293.54

6.8

5.6

40.60

39.60

mmol/mol

61.19

29133

228852

Other diseases of upper respiratory tract

56473

268763

1.41

293.23

5.8

5.4

39.37

39.47

mmol/mol

1.71

52577

249293

Polyarthropathies

32126

189514

1.57

293.19

6.8

5.1

40.36

39.40

mmol/mol

48.98

30075

175747

Autoimmune diseases excluding thyroid diseases, strict definition

51142

258331

1.42

291.80

7.0

4.8

42.40

38.49

mmol/mol

307.65

48023

240436

Asthma, excluding more controls

40176

192858

1.53

287.91

6.0

4.9

39.84

38.73

mmol/mol

89.04

37949

179686

Any gastric operation

44622

200824

1.43

287.48

5.6

4.7

39.01

38.84

mmol/mol

3.38

41516

188261

GASTRO-related operations

44622

200824

1.43

287.48

5.6

4.7

39.01

38.84

mmol/mol

3.38

41516

188261

Abdominal and pelvic pain

53447

244367

1.41

285.65

6.0

5.2

39.71

39.23

mmol/mol

22.49

49903

227323

Anxiety (asthma-related co-morbidities)

28024

195008

1.63

283.45

5.5

4.6

38.25

38.54

mmol/mol

5.22

26231

184028

Fall on same level

57953

296732

1.39

276.71

5.9

5.2

39.81

39.09

mmol/mol

52.34

53592

277177

Benzodiazepine use

47931

311178

1.45

276.64

6.5

5.3

39.60

39.38

mmol/mol

5.20

43774

290191

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

22145

94725

1.63

275.19

5.2

4.2

39.04

38.47

mmol/mol

14.14

20779

88615

Asthma (mode)

40595

201406

1.50

274.79

6.0

5.0

39.83

38.92

mmol/mol

63.58

38354

187575

Coxarthrosis, primary

24415

189028

1.85

272.53

6.9

6.3

40.33

40.58

mmol/mol

4.68

22748

172098

Non-invasive ventilation

9485

72048

2.47

270.74

6.1

3.1

40.13

36.39

mmol/mol

262.27

9170

66077

Psychiatric diseases

56827

260836

1.39

270.53

6.2

5.2

39.80

39.17

mmol/mol

38.99

52572

243442

Heart failure and antihypertensive medication

10322

54735

2.21

270.10

9.0

3.8

44.65

37.75

mmol/mol

307.65

9732

49717

Use of hypnotics and sedatives

52602

279197

1.43

269.63

6.4

5.4

39.68

39.49

mmol/mol

4.35

48806

260110

Actinic keratosis

13901

112853

2.28

269.63

7.0

6.8

40.19

41.12

mmol/mol

28.25

12575

101486

Skin changes due to chronic exposure to nonionizing radiation

14340

116405

2.24

267.18

7.0

6.7

40.16

41.07

mmol/mol

27.58

12985

104757

Cholelithiasis

38935

247854

1.52

265.35

7.0

5.5

40.82

39.39

mmol/mol

145.21

36091

229127

Continuous positive airway pressure

8306

57414

2.74

264.32

9.4

3.3

43.01

36.74

mmol/mol

307.65

7608

52238

Asthma

41228

200289

1.48

263.46

6.0

5.0

39.89

38.90

mmol/mol

72.46

38900

186531

Migraine

21986

162980

1.69

263.22

4.7

4.4

37.33

38.08

mmol/mol

35.11

20877

152556

Disorders of lens

30561

173301

1.65

262.00

7.9

5.7

42.41

39.78

mmol/mol

288.18

27825

160500

Disorders of gallbladder, biliary tract and pancreas

46517

274425

1.46

260.24

7.1

5.4

41.30

39.38

mmol/mol

275.89

43268

254527

Personality disorders, excluding more controls

11183

92515

2.19

257.20

6.5

4.3

39.27

38.23

mmol/mol

19.73

10484

87779

Genitourinary diseases

32287

143181

1.49

256.77

5.8

4.7

39.62

39.00

mmol/mol

22.42

30318

134161

All anxiety disorders

28364

203110

1.58

254.87

5.5

4.7

38.21

38.55

mmol/mol

7.23

26547

191608

Asthma (diagnoses ohter than nonallergic)

39897

309659

1.46

253.76

6.2

5.3

40.06

39.19

mmol/mol

55.91

37567

287215

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

6060

74924

0.47

252.28

5.6

6.5

41.36

40.62

mmol/mol

5.69

5345

68813

15295

124559

2.09

250.67

6.9

6.6

40.21

40.97

mmol/mol

20.36

13872

112345

Paracetamol of NSAID medication

9534

36562

1.85

250.39

5.1

4.4

39.11

38.69

mmol/mol

3.38

8871

33886

Cholelithiasis, broad definition with cholecystitis

40286

251814

1.49

247.59

7.0

5.5

40.89

39.39

mmol/mol

161.16

37352

232852

Menorrhagia

16261

77082

1.91

247.44

5.9

4.8

39.26

38.68

mmol/mol

12.16

14989

71602

Anxiety disorders

43058

278758

1.45

247.09

5.8

5.1

38.81

39.03

mmol/mol

4.84

40258

260688

Cerebrovascular diseases (FINNGEN)

14902

91684

2.04

245.80

6.9

4.1

40.97

38.09

mmol/mol

204.26

14074

84492

Symptoms and signs involving the digestive system and abdomen

53264

244376

1.37

245.31

6.0

5.2

39.73

39.23

mmol/mol

23.36

49607

227332

Degeneration of macula and posterior pole

17984

129356

1.87

245.25

7.4

6.4

41.65

40.51

mmol/mol

42.97

16087

116838

Neurotic, stress-related and somatoform disorders

42578

276481

1.45

244.57

5.8

5.1

38.78

39.01

mmol/mol

4.89

39815

258631

Other cataract

18108

122175

1.85

243.55

7.8

5.9

42.40

39.93

mmol/mol

151.51

16539

112267

Senile cataract

27623

153781

1.66

243.04

7.8

5.9

42.31

39.94

mmol/mol

222.51

24979

141678

Intracranial trauma

27558

182063

1.52

242.76

5.8

4.5

39.71

38.44

mmol/mol

86.25

25527

169292

Other anxiety disorders

20074

154940

1.68

241.10

5.4

4.5

38.08

38.25

mmol/mol

1.53

18795

146332

Other diseases of urinary system

49802

256785

1.39

239.58

6.1

5.3

39.74

39.20

mmol/mol

27.10

46263

238195

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

22621

126470

1.69

239.45

5.8

3.9

39.50

37.69

mmol/mol

157.12

21315

117874

Exclusions for E4_PCOS_CONSORTIUM

33361

188740

1.52

236.38

5.6

4.9

38.95

38.59

mmol/mol

10.37

30811

176589

Asthma, unspecified (mode), excluding more controls

24795

173546

1.65

236.19

6.6

5.0

40.48

38.86

mmol/mol

117.76

23251

161147

Propionic acid derivatives

14495

59674

1.67

235.60

5.3

5.1

39.19

39.48

mmol/mol

2.73

13485

55030

Persons encountering health services in other circumstances

16277

140517

1.83

235.36

6.1

5.1

39.80

38.91

mmol/mol

22.25

14938

130224

STROKE

26558

166151

1.70

234.64

7.1

4.8

41.06

38.35

mmol/mol

307.65

24960

152201

Complications of procedures, not elsewhere classified

36582

288248

1.50

234.09

6.5

5.4

40.30

39.42

mmol/mol

50.45

34236

267355

Schizophrenia or delusion, excluding more controls

13269

111947

1.98

234.03

6.9

4.8

39.52

38.88

mmol/mol

10.76

12453

105409

COPD, hospital admissions 1, only main diagnosis

9514

98026

0.58

232.08

7.5

6.6

42.66

40.86

mmol/mol

50.59

8499

89031

Benign neoplasm of colon, rectum, anus and anal canal

25402

206726

1.71

232.05

7.6

6.1

40.97

40.33

mmol/mol

22.10

23639

189008

Fitting and adjustment of other devices

13956

111487

2.00

231.57

7.4

6.2

41.58

40.43

mmol/mol

36.20

12592

100990

Care involving use of rehabilitation procedures

28839

246943

1.58

231.48

6.9

5.4

40.58

39.44

mmol/mol

68.29

27544

228685

Diabetes mellitus in pregnancy

13598

74108

1.86

231.15

6.2

3.4

41.14

36.31

mmol/mol

307.65

13016

70912

Exposure to unspecified factor

45319

322874

1.41

229.08

5.8

5.3

39.43

39.27

mmol/mol

2.61

41960

300765

Ovarian cyst

16845

83853

1.78

228.92

5.3

4.6

38.25

38.30

mmol/mol

0.30

15632

78076

Gastrointestinal diseases

33384

149293

1.44

228.75

5.4

4.4

38.90

38.45

mmol/mol

12.99

31314

139400

Presence of cardiac and vascular implants and grafts

18239

120815

1.80

228.21

8.5

6.2

43.31

40.50

mmol/mol

211.31

16878

110025

Concussion

23177

176375

1.56

227.61

5.8

4.6

39.57

38.48

mmol/mol

56.07

21534

163957

Disorders of synovium and tendon

24358

196375

1.64

224.25

6.3

5.1

40.17

39.12

mmol/mol

52.56

22890

182317

Later onset COPD

6854

67450

0.54

224.09

7.4

7.1

42.79

41.42

mmol/mol

19.43

6063

60264

Benign neoplasms

39358

202037

1.42

223.71

5.7

4.8

39.20

38.82

mmol/mol

11.70

37012

190134

Ischaemic heart disease, wide definition

34840

200153

1.58

222.81

8.2

5.6

42.79

39.64

mmol/mol

307.65

32804

183646

Ischemic heart diseases

35357

203312

1.57

221.67

8.1

5.6

42.73

39.61

mmol/mol

307.65

33339

186618

Symptoms and signs involving the skin and subcutaneous tissue

29994

270903

1.55

219.44

6.1

5.5

39.26

39.44

mmol/mol

2.66

28160

251167

Constipation

39345

257978

1.45

218.55

6.9

5.6

40.23

39.69

mmol/mol

22.03

36028

238803

Any mental disorder

57386

265884

1.34

218.28

6.2

5.2

39.83

39.22

mmol/mol

36.47

53052

248006

Unspecified mental disorder

17695

155123

1.76

217.66

7.0

5.0

39.57

38.99

mmol/mol

12.01

16640

145322

Kela-code for severe mental illness

15820

137951

1.82

213.11

7.2

5.1

39.62

39.09

mmol/mol

9.12

14845

129126

Dermatitis and eczema

52128

316203

1.35

210.78

5.9

5.3

39.28

39.31

mmol/mol

0.22

48690

294117

Mouth breathing

16851

149537

1.93

209.04

6.6

5.6

40.34

39.73

mmol/mol

12.80

15967

139582

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

3351

43342

0.46

208.71

5.8

6.8

41.23

41.16

mmol/mol

0.15

2933

39430

Other disorders of skin and subcutaneous tissue

29173

242704

1.54

208.37

7.4

5.7

41.58

39.69

mmol/mol

148.81

27154

223565

10329

76458

2.04

208.05

7.5

6.7

41.99

40.94

mmol/mol

21.33

9108

68400

Anti-inflammatory and antirheumatic products, non-steroids

14337

59678

1.61

207.82

5.3

5.1

39.26

39.48

mmol/mol

1.58

13303

55034

Asthma, unspecified (mode)

25246

179809

1.58

207.12

6.6

5.2

40.53

39.04

mmol/mol

101.21

23644

166884

Factors influencing health status and contact with health services

17913

76961

1.59

207.06

5.8

4.5

40.16

38.81

mmol/mol

49.29

16726

71509

First line medication for Crohn's disease

56189

283899

1.32

205.65

6.1

5.2

39.43

39.19

mmol/mol

6.76

52606

264038

Pacemaker

11880

98608

1.99

204.86

7.7

6.7

42.50

41.03

mmol/mol

42.56

10869

88865

Asthma (only as main-diagnosis), excluding more controls

35535

192858

1.44

203.79

5.9

4.9

39.76

38.73

mmol/mol

71.98

33502

179686

Chronic lower respiratory diseases

59900

301186

1.32

203.62

6.0

5.2

39.86

39.11

mmol/mol

61.35

56181

280025

Presence of other devices

8670

71565

2.21

203.45

6.8

6.1

41.05

40.31

mmol/mol

11.02

8225

64857

Fenamates

6943

36966

2.29

203.35

5.6

5.2

38.85

39.55

mmol/mol

8.48

6471

34046

Coxarthrosis, primary, with hip surgery

18189

154139

1.86

202.33

6.7

6.4

40.15

40.71

mmol/mol

17.44

16923

139710

COPD, hospital admissions 3, with asthma pneumonia sepsis

6765

71637

0.56

202.01

7.4

6.6

43.28

41.02

mmol/mol

50.65

6033

64834

Insulin, fast-acting (human)

5975

47513

2.74

199.65

16.3

4.1

63.00

37.13

mmol/mol

307.65

5737

44543

Visual disturbances and blindness

20689

184821

1.66

198.82

6.5

5.6

39.72

39.59

mmol/mol

1.12

19190

170645

Glucosamine medication

20180

145086

1.79

196.58

6.9

6.4

40.20

40.60

mmol/mol

9.54

18267

131569

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

14096

125412

0.63

196.05

6.7

6.4

41.71

40.61

mmol/mol

28.20

12790

115226

Disorders of adult personality and behaviour

11819

101129

1.92

194.51

6.4

4.6

39.17

38.31

mmol/mol

14.64

11081

95627

Endometriosis

15741

81420

1.74

192.97

5.1

4.7

38.25

38.41

mmol/mol

1.49

14613

75767

COPD, early/later onset

13928

134524

0.63

192.83

7.5

6.5

42.48

40.70

mmol/mol

68.57

12536

122605

Other and unspecified nonorganic psychotic disorders

7901

65320

2.28

189.48

6.3

4.5

38.50

38.45

mmol/mol

0.16

7470

61733

Gestational diabetes (for exclusion)

14829

90648

1.71

189.27

5.5

3.7

39.77

36.68

mmol/mol

244.93

14133

86567

Bipolar affective disorders

7772

64167

2.29

188.81

6.5

4.5

38.51

38.36

mmol/mol

0.65

7321

60659

Benign neoplasm: Colon

20767

183862

1.72

187.49

7.8

6.2

41.09

40.44

mmol/mol

19.09

19330

167828

Falls/tendency to fall

57068

265526

1.30

186.88

5.7

5.2

39.50

39.05

mmol/mol

20.41

52978

248173

Personality disorders

11183

95781

1.95

185.79

6.5

4.6

39.27

38.35

mmol/mol

15.64

10484

90538

COPD, hospital admission 2, with asthma infections

8697

88694

0.60

184.36

7.5

6.5

43.08

40.83

mmol/mol

65.95

7797

80643

Schizophrenia or delusion

13269

115357

1.83

184.23

6.9

5.0

39.52

39.01

mmol/mol

6.98

12453

108239

Cough

17660

150035

1.66

184.04

6.4

5.2

39.82

39.25

mmol/mol

10.78

16382

138125

Benign neoplasm of colon, rectum, anus and anal canal

23929

155532

1.65

183.66

7.5

5.9

40.92

40.13

mmol/mol

30.30

22277

143879

Asthma (only as main-diagnosis)

36222

200289

1.41

181.63

6.0

5.0

39.82

38.90

mmol/mol

56.93

34103

186531

Schizophrenia, schizotypal and delusional disorders

13312

115875

1.82

181.44

6.9

5.0

39.51

39.03

mmol/mol

6.39

12492

108712

COPD, hospital admissions

13855

133675

0.64

180.64

7.5

6.5

42.48

40.70

mmol/mol

68.09

12473

121821

Sub-endpoint used in defining T1D endpoints

11999

100410

1.74

180.46

15.4

5.0

61.27

38.60

mmol/mol

307.65

11455

93179

Provisional assignment of new diseases of uncertain etiology

18299

162461

1.63

179.98

6.9

5.1

40.11

38.92

mmol/mol

46.07

17203

151628

Codes for special purposes

18321

162680

1.63

179.75

6.9

5.1

40.12

38.92

mmol/mol

46.83

17221

151824

Visual disturbances

19107

171216

1.66

178.57

6.3

5.6

39.50

39.53

mmol/mol

0.12

17873

158258

Covid-19 confirmed case

10969

94414

1.98

178.44

6.9

5.4

40.44

39.40

mmol/mol

21.21

10270

87464

Symptoms and signs involving the urinary system

33384

236822

1.43

177.40

7.1

5.7

40.56

39.85

mmol/mol

32.64

30408

218835

Symptoms and signs involving the nervous and musculoskeletal systems

24005

217545

1.54

175.79

6.1

5.6

39.75

39.59

mmol/mol

1.76

22668

200998

Other external causes of accidental injury

44545

205584

1.33

174.63

5.6

5.1

39.39

39.08

mmol/mol

7.91

41292

192235

Specific personality disorders

9589

81575

2.00

171.69

6.4

4.6

39.16

38.31

mmol/mol

11.55

8990

77084

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

4541

55771

0.48

170.82

6.0

6.4

42.10

40.59

mmol/mol

15.83

4055

51180

Diseases of inner ear

22199

197835

1.62

170.04

6.3

5.9

39.89

39.99

mmol/mol

1.05

20298

182134

Irritable bowel syndrome

11493

99903

1.93

169.59

6.2

5.1

38.85

39.01

mmol/mol

1.01

10707

92727

Disorders of vestibular function (Vertigo)

18623

167131

1.72

169.17

6.5

5.9

39.99

39.98

mmol/mol

0.03

17008

153603

Diseases of male genital organs

23743

107399

1.47

167.85

6.3

5.6

40.52

40.21

mmol/mol

4.42

22160

100818

Abnormal findings on examination of blood, without diagnosis

18237

153013

1.65

167.30

7.3

6.1

42.10

40.29

mmol/mol

79.61

17328

140498

Diseases of arteries, arterioles and capillaries (FINNGEN)

10791

65281

2.00

165.87

8.3

4.4

43.15

38.36

mmol/mol

279.73

10101

59472

Complications of medical and surgical care

31573

276223

1.44

165.04

6.7

5.6

40.34

39.55

mmol/mol

35.55

29417

255626

Benign neoplasm: Colon

20449

142505

1.68

163.38

7.7

6.1

41.09

40.26

mmol/mol

28.76

19039

131396

Irregular menses

20143

146673

1.55

162.31

5.2

4.5

38.16

37.88

mmol/mol

4.42

18982

137797

Non-small cell lung cancer

3351

44609

0.50

161.97

5.8

6.7

41.23

41.12

mmol/mol

0.25

2933

40311

Accidents

44413

205584

1.31

161.69

5.6

5.1

39.38

39.08

mmol/mol

7.47

41184

192235

Chronic rhinitis, nasopharyngitis and pharyngitis

13198

116550

1.81

158.81

5.9

5.2

38.71

39.19

mmol/mol

8.99

12357

108740

Hernia

43863

276950

1.33

157.69

6.1

5.5

39.74

39.60

mmol/mol

2.55

40865

257200

Other disorders of eyelid

17419

151644

1.68

156.65

6.8

6.2

40.37

40.38

mmol/mol

0.02

15957

138177

Migraine with aura

9677

82436

1.85

156.48

4.7

4.3

37.19

37.83

mmol/mol

11.36

9217

77342

Hard cardiovascular diseases

34876

208265

1.45

156.01

7.8

5.7

42.47

39.66

mmol/mol

307.65

32871

191307

Injuries to the head

51961

316250

1.29

155.52

5.9

5.3

39.71

39.23

mmol/mol

22.88

47883

294738

Disturbances of skin sensation

10944

95667

1.92

153.68

5.8

5.0

38.48

38.88

mmol/mol

4.75

10341

89592

Dermatitis

25933

237643

1.47

152.72

6.6

5.5

40.14

39.48

mmol/mol

22.81

24169

220229

Asthma, hospital admissions , main diagnosis only

37329

309380

1.34

152.18

6.0

5.3

39.84

39.17

mmol/mol

32.89

35117

287386

Behavioural syndromes associated with physiological disturbances and physical factors

12561

109311

1.67

151.58

5.9

4.7

38.78

38.30

mmol/mol

5.44

11790

102767

Chronic kidney disease

10461

89587

1.78

150.63

12.1

6.2

44.67

40.68

mmol/mol

187.84

9924

81145

Parodontitis or/and operation codes

29061

160325

1.53

150.22

6.5

5.4

40.26

39.09

mmol/mol

70.35

26964

150668

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

22733

203061

1.52

150.08

6.0

5.4

39.30

39.53

mmol/mol

3.24

21199

189320

7124

56082

2.06

149.60

7.4

6.7

41.80

40.97

mmol/mol

9.78

6205

50087

Other hearing loss

10107

85174

1.78

149.51

6.6

6.3

40.90

40.72

mmol/mol

1.07

8947

77399

Myalgia

9271

79930

1.97

148.95

6.3

4.9

39.34

38.80

mmol/mol

6.07

8565

74303

Gout

10094

79009

1.80

148.10

9.1

6.2

42.91

41.02

mmol/mol

61.72

9420

71474

Polyp of the female genital tract

13860

71345

1.73

147.35

5.7

5.0

39.20

38.94

mmol/mol

2.83

12762

66169

COPD related to multimorbidity

11469

110220

0.65

146.68

8.3

6.6

43.69

40.86

mmol/mol

125.41

10349

100105

Coronary atherosclerosis

29269

174974

1.48

146.09

8.5

5.8

43.38

39.80

mmol/mol

307.65

27438

159688

Hyperplasia of prostate

14991

75541

1.62

145.12

6.9

6.3

40.81

41.06

mmol/mol

2.35

13673

70097

Disorders of vitreous body

19260

173022

1.70

144.05

7.4

6.1

41.53

40.10

mmol/mol

56.80

17867

158491

Noninflammatory disorders of female genital tract

19673

88101

1.46

143.33

4.9

4.5

37.98

38.17

mmol/mol

2.05

18288

81988

Disorders of lacrimal system

16726

151198

1.65

143.08

6.5

5.6

39.52

39.60

mmol/mol

0.50

15471

139371

Other reaction to severe stress, and adjustment disorders

15458

137519

1.58

142.32

5.8

4.6

39.12

38.39

mmol/mol

15.46

14503

129855

Infections, IBD-co-morbidities

6778

40166

1.87

141.36

7.2

2.9

40.45

36.44

mmol/mol

190.60

6350

36839

Disorders of vitreous body and globe

19801

177423

1.66

141.01

7.3

6.1

41.52

40.11

mmol/mol

57.22

18366

162514

Other/unspecified dorsalgia

15902

141334

1.58

140.68

6.3

5.3

39.95

39.39

mmol/mol

10.30

14850

130463

Other and unspecified dermatitis

21238

193665

1.51

140.14

6.5

5.5

40.04

39.42

mmol/mol

17.06

19815

179469

Disorders of other endocrine glands

17451

154119

1.54

140.00

6.9

5.3

39.65

39.25

mmol/mol

6.32

16312

142667

Panic disorder

5807

47454

2.13

139.81

5.5

4.2

38.12

37.83

mmol/mol

1.43

5429

44954

Nonorganic sleeping disorders, excluding more controls

7061

59214

2.02

139.37

5.9

4.6

38.31

38.51

mmol/mol

1.06

6649

55842

Haemorrhage from respiratory passages

13800

113127

1.61

139.35

7.2

5.8

41.21

40.05

mmol/mol

36.76

12630

103125

Other disorders of lacrimal gland

13362

119779

1.79

139.28

6.6

5.6

39.53

mmol/mol

0.01

12351

110553

Injuries to the shoulder and upper arm

37051

289135

1.34

139.26

6.1

5.6

39.92

39.64

mmol/mol

6.56

34395

268180

Oedema, not elsewhere classified

12527

110492

1.74

138.64

7.4

5.7

41.28

39.76

mmol/mol

47.74

11560

101312

Syncope and collapse

18919

150974

1.50

138.36

6.6

5.7

40.54

39.74

mmol/mol

21.62

17333

138443

Internal derangement of knee

16533

147987

1.57

138.31

5.8

5.2

39.54

39.53

mmol/mol

0.07

15251

137220

Glaucoma

22195

178112

1.49

137.66

7.0

6.2

41.41

40.38

mmol/mol

41.00

20044

162621

Hallux valgus (acquired)

14753

95685

1.68

136.98

5.6

5.4

38.70

39.69

mmol/mol

41.86

13511

87658

Pain and other conditions associated with female genital organs and menstrual cycle

8059

65168

1.83

136.74

4.8

4.2

37.35

37.67

mmol/mol

2.72

7520

61253

Adjustment and management of implanted device

6602

55507

2.15

136.59

7.8

6.4

42.46

40.74

mmol/mol

34.41

6125

50098

Hyperkinetic disorders, excluding more controls

3540

25468

2.21

136.40

4.1

3.0

36.44

36.45

mmol/mol

0.01

3307

24445

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

13120

117287

1.75

136.13

6.4

5.4

39.70

39.29

mmol/mol

5.58

12321

108799

Other chronic obstructive pulmonary disease

13797

128516

0.68

135.97

7.5

6.4

42.47

40.57

mmol/mol

77.23

12427

116805

Dipeptidyl peptidase 4 (DPP-4) inhibitors

4209

34682

3.61

135.26

15.8

4.4

55.67

37.73

mmol/mol

307.65

3965

31426

Presbycusis

4576

35782

2.16

135.18

6.8

41.93

41.59

mmol/mol

1.41

3832

31940

Subjective visual disturbances

9309

81549

2.00

135.14

6.3

5.5

39.05

39.41

mmol/mol

3.54

8766

75503

Pain, not elsewhere classified

11192

98453

1.75

133.55

6.3

5.2

39.74

39.12

mmol/mol

9.05

10504

91329

Malaise and fatigue

20897

157816

1.45

133.52

7.0

5.6

41.10

39.61

mmol/mol

67.81

19276

144997

Malignant neoplasm of digestive organs

10982

123248

0.67

132.45

6.7

6.5

41.88

40.83

mmol/mol

19.55

9870

111920

Diaphragmatic hernia

14103

127186

1.73

132.20

6.9

6.1

40.16

40.26

mmol/mol

0.61

13143

116329

Diseases of pulp and periapical tissues

14653

131378

1.62

130.84

7.1

5.2

40.65

39.46

mmol/mol

30.97

13605

122422

Generalized anxiety disorder

5862

48204

2.03

130.39

5.4

4.2

37.64

37.74

mmol/mol

0.34

5470

45624

Other blood glucose lowering drugs, excl. Insulins

6176

52374

2.32

129.60

15.1

4.4

55.33

37.73

mmol/mol

307.65

5809

47356

Emotionally unstable personality disorder

4722

38247

2.34

129.50

6.1

4.1

38.39

37.57

mmol/mol

5.80

4430

36289

Asthma/COPD (KELA code 203)

45464

300160

1.28

128.53

6.0

5.2

39.84

39.12

mmol/mol

48.33

42724

279050

Migraine without aura

7866

66682

1.81

127.78

4.5

4.0

36.89

37.46

mmol/mol

8.76

7504

62958

Other functional intestinal disorders

18269

156894

1.47

127.55

6.8

5.5

40.44

39.69

mmol/mol

17.76

16875

144049

Non-rheumatic valve diseases

19585

130224

1.51

127.26

6.9

5.8

40.63

39.88

mmol/mol

20.09

17890

118909

Valvular heart disease excluding rheumatic fever

19667

130904

1.51

127.10

6.9

5.8

40.61

39.87

mmol/mol

19.75

17969

119551

Fibromyalgia

3430

27596

3.76

127.07

6.2

4.5

38.72

38.28

mmol/mol

2.26

3255

25862

Wet age-related macular degeneration

5620

45663

2.14

126.61

7.5

6.7

42.30

41.09

mmol/mol

15.23

4981

40705

Chronic sinusitis

18431

167637

1.52

126.53

5.8

5.3

39.27

39.30

mmol/mol

0.16

17274

156198

COPD

14507

133077

0.69

125.95

7.4

6.4

42.37

40.53

mmol/mol

75.93

13086

121056

Impingement syndrome of shoulder

10218

91273

2.00

125.62

6.6

5.6

40.39

39.75

mmol/mol

10.10

9536

84338

Basal cell carcinoma, including avohilmo

22164

160056

1.45

123.55

6.6

6.5

40.26

40.77

mmol/mol

12.13

19965

145327

Heart failure, not strict

32314

208251

1.39

122.63

9.3

5.6

43.79

39.55

mmol/mol

307.65

30267

191305

Female genital prolapse

12775

65718

1.68

121.94

5.7

5.1

39.26

39.23

mmol/mol

0.14

11880

60752

Myocardial infarction, unclassifiable

5420

59474

0.62

121.92

8.3

6.7

44.78

41.42

mmol/mol

77.45

4957

53370

External causes of morbidity and mortality

36272

168351

1.29

121.15

5.5

5.0

39.27

38.91

mmol/mol

9.65

33763

157359

Postmenopausal atrophic vaginitis

10494

56353

1.94

120.77

5.7

5.4

39.02

39.60

mmol/mol

11.64

9820

51947

Disorders of conjunctiva

36515

285529

1.31

120.74

5.5

5.2

38.82

39.05

mmol/mol

4.82

34072

266115

Vocal cord dysfunction

5678

43632

2.01

120.25

6.1

3.0

39.37

36.44

mmol/mol

121.00

5244

40210

Polyuria

8210

71612

1.95

120.06

7.4

6.1

40.19

40.27

mmol/mol

0.31

7489

65770

Polyarthrosis

7662

63866

2.04

120.03

7.0

5.8

40.39

40.28

mmol/mol

0.43

7075

57682

Inflammatory diseases of female pelvic organs

26034

181314

1.40

119.66

5.5

4.9

38.61

38.37

mmol/mol

3.71

24071

168887

Other symptoms and signs involving the nervous and musculoskeletal systems

16845

152951

1.53

119.50

5.9

5.5

39.49

39.39

mmol/mol

0.68

16015

141705

Benign paroxysmal vertigo

10775

96540

1.86

118.99

6.6

5.9

40.14

39.96

mmol/mol

1.27

9810

88663

Other systemic involvement of connective tissue (FG)

10133

88650

1.74

118.98

6.5

5.5

39.50

39.61

mmol/mol

0.54

9472

80808

Postmenopausal bleeding

11402

55934

1.80

117.97

6.6

5.4

40.19

39.74

mmol/mol

5.89

10374

51394

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

25456

235090

1.41

117.63

6.7

5.7

40.37

39.65

mmol/mol

24.10

23756

217167

Conduction disorders

11363

83427

1.64

117.15

7.6

5.9

41.96

40.03

mmol/mol

66.31

10322

75693

Hernia of abdominal wall, postoperative

7271

63314

2.10

116.32

7.5

5.6

40.84

39.94

mmol/mol

13.15

6785

58755

Non-selective monoamine reuptake inhibitors

16411

144806

1.54

115.96

7.4

5.5

40.77

39.76

mmol/mol

32.79

15106

133662

Acute upper respiratory infections

49696

293287

1.25

115.58

5.7

5.4

39.54

39.30

mmol/mol

6.14

46422

272120

Basal cell carcinoma

21497

157326

1.44

115.10

6.6

6.5

40.28

40.79

mmol/mol

11.93

19346

142790

Other pulmonary diagnosis

43062

202228

1.28

115.06

5.8

5.0

39.70

38.91

mmol/mol

44.87

40249

188340

AV-block

6309

48055

1.88

114.25

8.1

6.3

42.76

40.48

mmol/mol

54.24

5714

43093

Schizophrenia

6406

55026

2.12

114.24

7.5

5.0

39.89

39.12

mmol/mol

7.50

6094

51847

Other enthesopathies

12654

114009

1.67

113.97

6.1

5.2

39.73

39.26

mmol/mol

6.48

11900

105860

Primary coxarthrosis, bilateral

10412

93137

1.82

113.25

6.9

6.4

40.47

40.77

mmol/mol

3.05

9641

84267

Sleep disorders

8153

70809

1.82

113.24

6.0

4.9

38.59

38.75

mmol/mol

0.72

7660

66465

Phobic anxiety disorders

5022

41061

1.99

112.96

5.4

4.0

37.97

37.69

mmol/mol

1.11

4691

39016

Other symptoms and signs involving cognitive functions and awareness

17251

147071

1.48

112.83

6.7

6.0

40.66

40.25

mmol/mol

5.66

15844

134508

Unspecified haematuria

16110

124852

1.50

112.78

7.1

6.2

40.81

40.46

mmol/mol

4.68

14706

114541

Bacterial pneumonia, not elsewhere classified

12912

127716

0.70

111.28

6.5

5.8

41.44

39.80

mmol/mol

54.25

12156

117360

Functional dyspepsia

10603

94664

1.75

111.16

6.6

5.3

39.75

39.34

mmol/mol

4.38

9840

87607

Excluding asthma or asthma-COPD overlap

43016

202228

1.27

111.16

5.8

5.0

39.71

38.91

mmol/mol

45.18

40221

188340

Disorders of skin appendages

19494

178166

1.43

111.00

6.2

5.1

39.60

38.87

mmol/mol

19.85

18340

166476

Bacterial pneumoniae

13787

135837

0.71

110.93

6.5

5.8

41.41

39.76

mmol/mol

58.56

12969

124955

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

6849

51688

1.64

109.91

4.3

3.5

37.01

36.64

mmol/mol

2.06

6422

49217

17900

161173

1.43

109.83

6.2

5.1

40.09

39.01

mmol/mol

39.21

16871

149852

COPD differential diagnosis

42841

201463

1.27

109.44

5.8

5.0

39.68

38.92

mmol/mol

41.91

40048

187631

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

4181

24525

2.07

108.74

6.9

3.3

41.35

36.97

mmol/mol

103.15

3882

21933

ILD differential diagnosis

42813

201406

1.27

108.14

5.8

5.0

39.68

38.92

mmol/mol

42.18

40023

187575

Certain infectious and parasitic diseases

51828

244875

1.23

107.89

6.1

5.0

40.16

38.76

mmol/mol

156.32

48372

228047

Soft tissue disorders related to use, overuse and pressure

10683

95750

1.74

107.84

6.5

5.5

40.09

39.65

mmol/mol

5.28

9999

88270

Injury, poisoning and certain other consequences of external causes

29720

137371

1.30

107.62

5.4

4.9

39.23

38.83

mmol/mol

9.21

27679

128122

Cervicobrachial syndrome

9039

80070

1.82

107.53

6.1

5.2

39.58

39.28

mmol/mol

2.43

8678

74287

Bacterial pneumonia (organism specified)

14498

146841

0.73

107.49

6.5

5.9

41.41

40.02

mmol/mol

44.05

13625

134660

Gout, idiopatic and unspecified

8437

74289

1.85

107.32

9.1

6.5

42.97

40.97

mmol/mol

58.74

7882

67665

Infections of the skin and subcutaneous tissue

24034

221129

1.37

107.08

7.0

5.2

41.65

39.11

mmol/mol

183.78

22467

206599

Diseases of external ear

12772

115060

1.59

106.61

6.8

5.7

40.34

39.68

mmol/mol

10.41

11357

106664

Excessive attrition of teeth

17372

86076

1.51

106.35

5.9

5.0

38.73

38.85

mmol/mol

0.99

16149

81090

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

11278

99662

1.55

105.92

5.9

4.3

38.77

38.17

mmol/mol

8.24

10464

94489

Paroxysmal tachycardia

9526

70799

1.68

105.81

6.3

4.1

39.98

37.88

mmol/mol

92.04

8908

64830

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

23496

218046

1.40

105.05

6.6

5.7

40.33

39.68

mmol/mol

18.96

21931

201343

Nonalcoholic fatty liver disease

3392

28275

3.83

104.76

10.0

5.3

43.64

39.33

mmol/mol

85.04

3273

26489

Cardiodefibrillation

13312

121094

1.65

104.58

6.9

6.6

41.11

40.89

mmol/mol

1.94

12344

110190

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

44468

273573

1.26

103.78

6.1

5.6

39.81

39.68

mmol/mol

2.02

41212

254209

Cervical disc disorders

15394

140914

1.55

103.03

6.5

5.6

40.14

39.88

mmol/mol

3.15

14415

129926

Any operation in hilmo

2606

9345

2.05

101.95

4.6

2.8

39.21

36.89

mmol/mol

21.42

2469

8976

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

44110

298506

1.25

101.91

7.1

5.3

40.86

39.31

mmol/mol

171.37

40791

277472

Glaucoma suspect

13428

122444

1.62

101.62

7.0

6.2

41.21

40.25

mmol/mol

22.13

12302

111901

Elevated blood glucose level

2936

23718

3.30

101.02

11.7

5.6

51.57

39.76

mmol/mol

232.26

2815

21940

Other and unspecified disorders of vitreous body

15596

143793

1.66

100.54

6.5

6.2

39.84

40.12

mmol/mol

3.19

14455

131493

Other menopausal disorders

11618

60493

1.70

99.87

4.7

5.1

37.71

39.12

mmol/mol

69.79

10905

56175

Nonorganic sleeping disorders

7061

61181

1.81

99.62

5.9

4.9

38.31

38.63

mmol/mol

2.18

6649

57513

Transplanted organ and tissue status

3461

28671

3.00

99.00

12.9

5.3

40.58

39.42

mmol/mol

8.45

3386

26784

Asthma, hospital admission 2, infections

24084

218892

1.33

99.00

6.4

5.4

40.49

39.30

mmol/mol

62.02

22655

202545

Asthma-related infections

24084

218892

1.33

99.00

6.4

5.4

40.49

39.30

mmol/mol

62.02

22655

202545

Blepharochalasis

10893

99066

1.79

98.33

6.9

6.2

40.26

40.32

mmol/mol

0.25

9960

90232

Exposure to other specified factors

32188

282975

1.29

97.77

5.5

5.3

39.12

39.18

mmol/mol

0.54

29914

264467

Exclusions for E4_PCOS_BROAD

6196

53367

1.92

97.56

6.9

5.2

39.80

39.07

mmol/mol

7.04

5883

49897

Angina pectoris

25015

158025

1.41

97.45

8.7

5.9

43.42

39.90

mmol/mol

307.65

23513

143629

Other neurological diseases

29898

225140

1.31

95.32

7.0

5.9

40.87

39.98

mmol/mol

46.06

28065

206454

Other abnormal uterine and vaginal bleeding

9306

58816

1.67

95.27

6.6

5.2

40.03

39.18

mmol/mol

14.60

8250

54083

Hernia of abdominal wall

17916

165483

1.46

94.79

7.2

5.8

41.01

39.96

mmol/mol

40.83

16738

153038

Intracranial injury

23733

212074

1.32

94.59

6.0

5.5

39.92

39.52

mmol/mol

7.70

21832

196597

Triptan medication for migraine, single purchase ok

35427

225547

1.28

94.47

4.4

5.0

37.45

38.84

mmol/mol

187.08

33536

211352

Migraine, single triptan purchase ok & required. ICD-code if available is included

35427

225547

1.28

94.47

4.4

5.0

37.45

38.84

mmol/mol

187.08

33536

211352

Other malignant neoplasms of skin (=non-melanoma skin cancer)

20908

152617

1.39

94.35

6.6

6.5

40.45

40.79

mmol/mol

5.20

18763

138572

Autoimmune diseases related-to ILD

38355

318125

1.26

94.05

6.1

5.4

39.66

39.31

mmol/mol

9.02

35968

295796

L04AD Calcineurin inhibitors

3791

31938

2.71

92.69

11.8

5.2

39.93

39.29

mmol/mol

3.50

3718

29976

Poisoning by drugs, medicaments and biological substances

9281

82198

1.61

92.62

6.4

4.7

39.54

38.52

mmol/mol

15.78

8632

77523

Special screening examination for other diseases and disorders

3278

26237

2.25

92.58

9.6

4.6

47.92

38.61

mmol/mol

217.93

3131

24144

55810

280104

1.20

91.98

6.0

5.3

39.97

39.17

mmol/mol

63.29

51867

259931

Poisoning by medicine

8357

73599

1.66

91.70

6.3

4.7

39.54

38.48

mmol/mol

15.10

7779

69430

Acute sinusitis

22683

195987

1.34

91.52

5.9

4.9

39.67

38.79

mmol/mol

31.83

21286

183717

Familial hypercholesterolemia

5693

49284

2.02

91.38

9.3

6.0

44.18

40.16

mmol/mol

131.41

5273

44387

Temporomandibular joint disorders, including avohilmo

16750

153122

1.41

91.25

5.0

4.7

37.36

38.28

mmol/mol

44.61

15709

143787

Spondylolisthesis/Spondylolysis

7128

63262

1.96

91.16

6.3

5.5

39.54

39.68

mmol/mol

0.67

6719

58255

Temporomandibular joint disorders

6610

57282

1.78

91.11

5.6

4.6

38.06

38.58

mmol/mol

5.67

6205

53358

Disturbance of activity and attention

3363

26049

1.95

90.42

4.0

3.4

36.33

36.56

mmol/mol

0.66

3137

24822

Neoplasms

39003

196257

1.23

89.45

5.2

4.8

38.83

38.75

mmol/mol

0.85

36663

184718

Other specified/unspecified arthritis

10653

95677

1.57

89.32

6.1

5.3

39.51

39.49

mmol/mol

0.05

9979

88173

Other extrapyramidal and movement disorders in other diseases

8083

72194

1.82

89.21

6.9

6.0

40.07

40.03

mmol/mol

0.12

7485

66346

Other hammer toe(s) (acquired)

6620

54770

1.97

89.14

6.3

5.9

39.32

40.33

mmol/mol

19.59

5967

49266

Secondary hypertension

2946

23432

2.51

89.11

11.7

4.3

42.10

38.21

mmol/mol

59.36

2820

21303

Deforming dorsopathies

11258

101648

1.56

88.95

5.9

5.3

39.12

39.29

mmol/mol

1.26

10545

93803

Rheumatism, unspecified

5501

48252

2.24

88.15

7.0

5.3

40.14

39.22

mmol/mol

11.81

5179

44369

Diseases of the respiratory system

34732

163247

1.26

88.14

5.7

5.1

39.55

38.93

mmol/mol

25.31

32361

151389

Dentofacial anomalies [including malocclusion]

11141

98859

1.52

88.13

5.5

4.6

38.10

38.55

mmol/mol

5.79

10528

92872

Insomnia

5866

50797

1.90

87.91

5.9

4.9

38.28

38.70

mmol/mol

3.04

5538

47714

Myocardial infarction, without ST-elevation

14355

120555

1.44

87.71

8.8

6.5

44.34

40.86

mmol/mol

232.57

13419

109074

Gout, strict definition

5869

51136

1.97

87.61

9.7

6.6

43.35

41.07

mmol/mol

52.70

5483

46522

Cervicalgia

8058

71581

1.73

87.24

6.3

5.4

39.69

39.52

mmol/mol

0.87

7526

65869

Emotional disorders starting during childhood or adolecense, excluding more controls

1459

9518

2.51

87.15

4.2

2.7

36.86

35.79

mmol/mol

3.00

1342

9085

Gout, unspecified

6784

59710

1.85

87.11

9.3

6.5

43.10

40.98

mmol/mol

51.96

6312

54339

Disorder of lipoprotein metabolism, unspecified

4864

41892

2.17

86.91

9.5

5.9

45.35

40.08

mmol/mol

146.69

4496

37850

Calcific aortic valvular stenosis, operated

9988

87203

1.55

86.75

7.9

6.8

42.50

41.26

mmol/mol

23.72

9149

78413

Calcific aortic valvular stenosis

9988

87203

1.55

86.75

7.9

6.8

42.50

41.26

mmol/mol

23.72

9149

78413

Calcific aortic valvular stenosis, diagnosis (helper)

9974

87098

1.55

86.36

7.9

6.8

42.51

41.27

mmol/mol

24.04

9135

78313

Operations 2 for CAVS

9974

87098

1.55

86.36

7.9

6.8

42.51

41.27

mmol/mol

24.04

9135

78313

Conjunctivitis

32656

267785

1.27

85.93

5.4

5.1

38.63

38.90

mmol/mol

5.91

30538

249878

Diarrhoea and gastroenteritis of presumed infectious origin

30602

260422

1.26

85.56

6.6

5.1

41.11

39.01

mmol/mol

179.57

28716

242448

Transient ischemic attack

20389

157030

1.38

85.33

7.4

6.2

41.32

40.41

mmol/mol

33.87

19176

142516

Enthesopathies of lower limb, excluding foot

8863

79509

1.69

85.14

6.1

5.2

39.29

39.31

mmol/mol

0.07

8279

73861

Hyperkinetic disorders

3559

27997

1.87

84.98

4.1

3.5

36.43

36.65

mmol/mol

0.62

3326

26671

Schizoaffective disorder

2862

23519

2.94

84.91

7.9

4.8

39.69

38.72

mmol/mol

5.57

2739

22182

Calcific aortic valvular stenosis, including rheumatic fever

10009

87447

1.54

84.49

7.9

6.8

42.51

41.26

mmol/mol

24.12

9166

78626

Acute upper respiratory infections of multiple and unspecified sites

33607

236506

1.25

84.46

5.6

5.1

39.35

38.99

mmol/mol

8.87

31520

220761

Dental caries

9987

88399

1.54

84.37

7.9

5.1

40.85

39.34

mmol/mol

29.52

9388

82425

Status post-ami

1291

15780

0.50

84.20

8.4

6.4

44.73

41.13

mmol/mol

26.61

1181

13780

Deviated nasal septum

13530

124083

1.51

84.03

6.1

5.7

39.60

39.98

mmol/mol

5.13

12647

115660

Other chronic obstructive pulmonary disease, including avohilmo

18003

161542

0.75

84.00

7.3

6.4

42.09

40.52

mmol/mol

73.49

16277

147732

Abnormal serum enzyme levels

10802

96853

1.61

83.91

6.4

6.5

40.10

40.80

mmol/mol

11.72

10312

88686

Malignant neoplasm of skin

24247

170568

1.33

83.66

6.6

6.4

40.39

40.66

mmol/mol

3.75

21771

155416

Later onset COPD, excluding more controls

6151

54566

0.63

83.58

7.5

6.8

42.62

40.75

mmol/mol

32.51

5491

48750

Other disorders of veins

15666

145123

1.50

83.36

5.9

5.7

39.22

39.64

mmol/mol

7.38

14325

134243

Leiomyoma of uterus

26883

143886

1.35

83.35

5.7

5.2

39.23

38.94

mmol/mol

6.51

24595

134104

Hypopituitarism

2418

19352

2.99

82.84

6.8

5.1

39.26

39.32

mmol/mol

0.11

2312

18214

Condition for Implicit Sepsis (Organ dysfunction codes)

37677

259007

1.25

82.61

7.2

5.5

41.10

39.44

mmol/mol

161.62

34825

239849

Vasomotor and allergic rhinitis

15856

142999

1.38

82.10

5.2

4.8

38.61

38.60

mmol/mol

0.03

14900

134287

Other and unspecified iron deficiency

11846

107202

1.48

81.69

7.9

5.7

42.08

39.74

mmol/mol

88.97

10827

98463

Pain in thoracic spine

5829

50931

1.87

80.56

5.8

5.1

39.00

39.14

mmol/mol

0.61

5554

47296

Other benign neoplasms of skin

14282

131363

1.46

80.35

6.5

5.9

40.01

39.93

mmol/mol

0.44

13108

120800

Umbilical hernia

10279

93433

1.61

79.62

7.2

5.8

40.99

40.07

mmol/mol

18.92

9670

86903

Dentinal caries

8741

77498

1.58

79.53

8.1

5.2

41.07

39.40

mmol/mol

30.40

8193

72251

Migraine without aura and triptan purchases

5946

51369

1.71

79.44

4.3

4.2

36.57

37.71

mmol/mol

28.63

5678

48663

Dislocation, sprain and strain of joints and ligaments of knee

26659

232564

1.30

79.31

5.2

5.1

38.76

38.94

mmol/mol

2.74

25226

218280

Migraine with aura and triptan purchases

5543

47682

1.76

79.18

4.4

4.3

36.62

37.81

mmol/mol

29.61

5299

45040

Restless leg syndrome

4237

36701

2.39

79.08

6.8

5.7

39.73

39.72

mmol/mol

0.04

3944

33892

Somatoform disorder

6187

54392

1.83

79.05

6.3

5.1

39.19

38.93

mmol/mol

1.35

5737

50866

Other diseases of anus and rectum

11454

103874

1.50

78.53

6.6

5.7

40.12

40.03

mmol/mol

0.37

10462

95130

Post-traumatic stress disorder

2904

23221

2.12

78.41

4.9

3.8

37.16

37.19

mmol/mol

0.05

2719

22094

Chronic gastritis

10504

95240

1.55

78.22

7.9

6.0

41.35

40.32

mmol/mol

17.30

9690

86591

Trigger finger

5483

48289

2.03

77.97

8.1

5.3

43.76

39.38

mmol/mol

122.69

5152

44750

Retinal detachments and breaks

13159

121016

1.50

77.91

6.8

6.0

40.75

40.05

mmol/mol

13.44

12036

110831

Thyrotoxicosis, other and/or unspecified

7418

66023

1.71

77.81

6.1

5.1

39.82

38.95

mmol/mol

11.53

6888

61251

Primary open-angle glaucoma

11140

98486

1.51

77.77

6.9

6.6

41.41

40.88

mmol/mol

7.02

9858

88809

Other skin changes

5907

52074

1.91

77.61

7.0

6.0

40.11

40.10

mmol/mol

0.01

5500

47751

Heartburn

3893

33211

2.26

77.21

6.4

5.3

39.42

39.31

mmol/mol

0.29

3596

30832

Other diseases of liver

6484

57750

1.88

76.74

8.7

5.5

42.25

39.57

mmol/mol

70.30

6141

53714

KRA_PSY_EATING, excluding more controls

2863

22377

1.92

76.16

5.0

3.2

37.41

36.25

mmol/mol

6.37

2665

21340

Squamous cell neoplasms and carcinomas of the skin

3843

32141

1.98

76.10

7.5

6.8

41.64

41.38

mmol/mol

0.69

3484

28775

Other arthritis (FG)

12297

112279

1.47

76.05

6.1

5.3

39.54

39.49

mmol/mol

0.20

11522

103506

Other noninflammatory disorders of uterus, except cervix

8766

53965

1.67

75.36

6.6

5.4

40.36

39.66

mmol/mol

10.77

8011

49476

Gout, FINNGEN

10094

91212

1.52

74.76

9.1

6.5

42.91

41.01

mmol/mol

63.46

9420

82833

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

18607

151490

1.37

74.44

5.9

4.6

39.75

37.93

mmol/mol

121.01

17740

141773

Injury of muscle and tendon at shoulder and upper arm level

13735

127599

1.53

74.43

6.4

6.1

40.29

40.33

mmol/mol

0.21

12902

118005

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

3843

32228

1.96

73.97

7.5

7.0

41.64

41.59

mmol/mol

0.09

3484

29043

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

6227

54632

1.71

73.66

6.3

4.6

39.28

38.34

mmol/mol

9.35

5767

51736

Triptan medication for migraine, min. 3 purchases

23601

174265

1.29

72.85

4.1

4.7

36.85

38.28

mmol/mol

160.94

22442

164319

Obsessive-compulsive disorder

2279

17778

2.25

72.73

5.2

3.8

37.10

37.36

mmol/mol

0.67

2130

16880

Any prescribed medicine buy

242

392

5.82

72.70

5.4

1.7

40.57

34.83

mmol/mol

11.88

230

372

Other systemic involvement of connective tissue

10294

93694

1.54

72.48

6.4

5.7

39.51

39.65

mmol/mol

0.85

9624

85954

Renal failure

15766

132784

1.37

72.31

10.7

6.2

44.39

40.52

mmol/mol

270.13

14776

120748

Trochanteric bursitis

5091

44923

2.06

72.19

6.6

5.4

39.72

39.49

mmol/mol

1.14

4755

41185

Pregnancy hypertension

16581

138531

1.38

72.12

5.8

4.5

39.74

37.81

mmol/mol

120.57

15811

130124

Other sleep disorders

4004

34191

2.04

71.81

7.5

5.2

40.93

39.24

mmol/mol

16.48

3772

31726

Implicit viral Sepsis

6780

59937

1.65

71.81

8.3

5.8

42.47

39.83

mmol/mol

60.93

6332

54874

Injuries to the wrist and hand

45167

312214

1.20

71.80

5.4

39.14

39.23

mmol/mol

1.20

42105

291060

Viral Sepsis

6794

60071

1.65

71.77

8.3

5.8

42.46

39.82

mmol/mol

60.74

6346

54996

Superficial injury of lower leg

9223

82908

1.51

71.67

6.2

5.2

39.76

39.03

mmol/mol

10.30

8571

77179

Systemic connective tissue disorders

13376

123224

1.44

71.60

6.5

5.7

39.52

39.69

mmol/mol

1.22

12549

113064

Renal tubulo-interstitial diseases

37439

272461

1.22

71.44

8.1

5.3

42.10

39.17

mmol/mol

307.65

34795

251961

Social phobias

2976

24121

2.00

70.92

5.1

3.9

37.42

37.56

mmol/mol

0.33

2777

22925

Primary open-angle glaucoma, strict

9036

81493

1.56

70.86

6.9

6.6

41.50

40.86

mmol/mol

8.01

7998

73491

Other maternal disorders predominantly related to pregnancy

24098

142038

1.30

70.83

5.6

4.5

39.63

37.69

mmol/mol

165.77

22863

132878

Symptoms and signs involving speech and voice

12358

113755

1.48

70.83

6.2

5.7

39.41

39.73

mmol/mol

3.60

11486

104910

Disorders of sclera, cornea, iris and ciliary body

22281

209075

1.31

70.39

6.2

5.5

40.20

39.42

mmol/mol

23.45

20801

194470

Iron deficiency anaemia

15421

140855

1.36

70.36

7.6

5.8

41.83

39.80

mmol/mol

91.11

14060

129291

Fibroblastic disorders

8963

80817

1.54

70.20

6.8

5.8

40.87

40.17

mmol/mol

9.06

8263

74054

Seborrhoeic keratosis

7979

72382

1.71

70.04

6.7

6.1

39.69

40.25

mmol/mol

7.88

7456

65991

In situ neoplasms

13299

122518

1.43

69.95

6.1

5.9

39.58

39.84

mmol/mol

2.92

12076

112176

Other disorders of teeth and supporting structures

8076

72678

1.61

69.49

7.6

5.4

41.12

39.69

mmol/mol

23.24

7506

67268

Macular pucker

4911

43714

2.23

69.45

7.4

6.5

41.15

40.45

mmol/mol

5.34

4452

39602

Fall on same level involving ice and snow

23242

218595

1.30

69.23

5.9

5.6

39.73

39.48

mmol/mol

3.44

21595

202641

Otitis externa

8030

72178

1.60

69.12

6.8

5.4

40.42

39.29

mmol/mol

19.07

7311

67319

Dysphagia

9161

83019

1.55

69.06

6.9

5.8

40.05

40.00

mmol/mol

0.20

8387

76031

Tinnitus

8799

80221

1.65

68.95

6.0

5.7

38.73

39.82

mmol/mol

31.81

8139

74379

ILD medications: immunosuppressive drugs

27288

247232

1.27

68.58

6.3

5.2

38.76

39.25

mmol/mol

15.43

25875

230105

4941

43041

1.84

68.44

6.3

4.8

39.16

38.58

mmol/mol

3.95

4671

40140

Non-small cell lung cancer, squamous, helper endpoint

691

10958

0.43

67.77

6.0

6.8

42.58

41.57

mmol/mol

1.70

604

9822

Non-small cell lung cancer, squamous

691

10958

0.43

67.77

6.0

6.8

42.58

41.57

mmol/mol

1.70

604

9822

Viral hepatitis, IBD co-morbidity

2067

16071

2.28

67.69

5.8

2.5

38.66

35.75

mmol/mol

28.00

1922

15091

Complications of internal orthopaedic prosthetic devices, implants and grafts

8016

72567

1.65

67.61

6.8

6.3

40.37

40.49

mmol/mol

0.55

7413

65819

Hypertrophy of breast in women and men

7344

66139

1.68

67.18

5.7

5.0

38.64

38.71

mmol/mol

0.33

6881

61881

Any dementia, excluding more controls

9938

76404

0.73

67.07

6.7

6.8

42.62

41.09

mmol/mol

31.73

8663

68681

Other diseases of lip and oral mucosa

5930

52675

1.78

67.05

6.6

5.5

40.05

39.77

mmol/mol

1.08

5543

48644

Any dementia

10453

81576

0.74

66.92

6.6

6.9

42.73

41.21

mmol/mol

32.16

9080

73238

Voice disturbances

9862

90347

1.56

66.87

6.0

5.7

38.91

39.59

mmol/mol

13.48

9232

83566

Persistent mood disorders

7443

66576

1.59

66.76

6.9

5.2

40.30

39.19

mmol/mol

15.35

6929

61947

Other benign neoplasms of skin

14282

129967

1.41

66.35

6.5

5.9

40.01

39.97

mmol/mol

0.17

13108

120056

Other CVD (FINNGEN)

4123

27784

1.91

66.20

8.3

4.7

42.65

38.47

mmol/mol

93.38

3781

24680

Thyrotoxicosis

9388

85603

1.55

66.14

6.3

5.4

40.01

39.24

mmol/mol

11.60

8716

79181

Diabetic nephropathy, excluding more controls

4504

41503

0.55

65.82

17.7

10.7

57.56

46.77

mmol/mol

307.65

4329

38973

Urticaria and erythema

14133

130447

1.38

65.81

5.8

5.1

39.24

38.86

mmol/mol

4.74

13165

121838

Supplementary factors related to causes of morbidity and mortality classified elsewhere

11514

105411

1.43

65.48

6.1

5.3

40.16

39.32

mmol/mol

15.03

10804

98139

Use of pramipexole

7775

70594

1.68

65.46

7.3

6.1

40.81

40.17

mmol/mol

7.13

7177

64677

Other and unspecified mood [affective] disorders

2549

20617

2.13

65.41

5.4

4.1

37.78

37.79

mmol/mol

0.03

2417

19533

Other and unspecified nerve root and plexus disorders, also in other diseases

7040

63486

1.71

65.40

6.3

5.2

39.94

39.20

mmol/mol

8.69

6645

59242

Other disorders of patella

7021

62828

1.63

65.34

5.4

4.7

38.63

38.83

mmol/mol

1.18

6570

58903

Emotional disorders and disorders of social functioning with onset specific to childhood

1580

11292

2.14

64.27

4.3

3.0

36.87

35.81

mmol/mol

3.12

1463

10695

Degenerative diseases of the nervous system

8854

74558

0.74

63.97

6.4

6.9

42.35

41.37

mmol/mol

12.17

7609

66941

Carcinoma in situ of skin of other and unspecified parts of face

2388

19620

2.47

63.84

7.0

6.9

40.53

41.45

mmol/mol

5.31

2146

17548

Chronic periapical parodontitis

7876

71280

1.60

63.83

7.4

5.4

40.98

39.71

mmol/mol

17.39

7273

66199

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

1484

11932

5.82

63.40

18.0

4.3

61.04

38.23

mmol/mol

307.65

1441

11461

Urticaria

11379

104194

1.42

63.30

5.7

5.0

39.06

38.68

mmol/mol

3.84

10612

97522

COPD (mode)

10822

93413

0.73

63.29

7.5

6.1

42.46

40.18

mmol/mol

83.67

9708

85091

Cutaneous abscess, furuncle and carbuncle

9569

87074

1.48

62.96

7.4

5.2

42.45

39.07

mmol/mol

109.88

8995

81432

Ill-defined and unknown causes of mortality

1303

17340

0.50

62.87

6.2

6.5

44.33

41.24

mmol/mol

13.45

1094

15737

Non-small cell lung cancer, adenocarcinoma

1290

16741

0.48

62.79

5.6

6.6

40.86

40.94

mmol/mol

0.10

1102

15164

Non-small cell lung cancer, adenocarcinoma, helper endpoint

1290

16741

0.48

62.79

5.6

6.6

40.86

40.94

mmol/mol

0.10

1102

15164

Maternal care for other conditions predominantly related to pregnancy

7647

67322

1.50

62.48

5.4

3.7

38.95

36.64

mmol/mol

79.47

7300

64145

Inflammatory diseases of prostate (prostatitis)

4486

39105

1.85

62.30

6.7

6.1

40.20

40.83

mmol/mol

4.56

4147

36314

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

1290

16726

0.48

62.23

5.6

6.7

40.86

41.03

mmol/mol

0.23

1102

15192

Papulosquamous disorders

15427

144146

1.39

62.09

6.7

5.7

40.47

39.67

mmol/mol

17.09

14377

133588

Benign neoplasm: Colon, unspecified

8562

78216

1.59

61.96

8.0

6.4

41.41

40.59

mmol/mol

11.21

7843

71326

Type of accident

10563

96623

1.44

61.45

6.0

5.4

40.10

39.36

mmol/mol

11.14

9897

89858

Hypertrophy of breast

6384

57463

1.72

61.14

5.5

4.9

38.36

38.46

mmol/mol

0.55

5978

53795

Diseases of appendix

33244

288280

1.22

61.09

5.4

5.3

39.37

39.21

mmol/mol

2.58

31272

269333

Other and unspecified polyneuropathies, also in other diseases

6473

58171

1.68

60.91

9.5

6.3

44.51

40.52

mmol/mol

103.79

6087

53278

Mixed and other personality disorders

2949

24989

2.24

60.86

6.9

4.6

39.39

38.44

mmol/mol

5.20

2786

23696

Allergic asthma (mode), excluding more controls

10241

91073

1.39

60.82

5.1

4.4

38.79

38.05

mmol/mol

11.24

9739

85449

Appendicitis, broad definition

32975

286935

1.22

60.48

5.4

5.3

39.38

39.20

mmol/mol

2.79

31028

268124

Thyroiditis, ILD-related definition

4203

36690

1.92

60.47

7.4

5.0

41.96

38.77

mmol/mol

54.12

3965

34144

Carcinoma in situ of skin of other and unspecified parts of face

2388

19760

2.41

60.35

7.0

40.53

41.59

mmol/mol

6.79

2146

17742

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

10343

92652

1.38

59.91

5.3

4.3

38.50

37.77

mmol/mol

10.50

9748

87650

Serous carcinoma of ovary, excluding all cancers (controls excluding all cancers)

757

9890

0.36

59.64

5.0

6.1

39.89

39.84

mmol/mol

0.03

677

9068

Open wound of head

20916

193216

1.27

59.49

6.0

5.7

39.85

39.86

mmol/mol

0.08

19002

179255

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

1640

19795

0.48

59.39

5.1

5.9

39.75

39.65

mmol/mol

0.15

1473

18232

Allergic asthma (mode)

10241

91217

1.39

59.25

5.1

4.4

38.79

38.13

mmol/mol

9.06

9739

85662

Polycystic ovarian syndrome

1865

14639

2.29

59.01

5.1

3.4

37.66

36.26

mmol/mol

9.99

1802

13878

Varicose veins

26864

192561

1.26

58.55

6.1

5.9

39.91

40.05

mmol/mol

1.74

24705

177205

Undetermined asthma, excluding more controls

4904

43226

1.77

58.52

6.4

5.2

40.10

38.95

mmol/mol

13.21

4582

39941

Erysipelas

22568

194379

1.28

58.16

7.8

5.8

42.81

39.89

mmol/mol

260.15

20927

178953

Non-small cell lung cancer, squamous, excluding all cancers (controls excluding all cancers)

691

10655

0.46

57.93

6.0

6.9

42.58

41.80

mmol/mol

1.13

604

9582

Flat foot [pes planus] (acquired)

3445

29913

2.14

57.69

6.7

5.3

39.71

39.50

mmol/mol

0.72

3180

27463

Endometriosis of pelvic peritoneum

6173

54177

1.58

57.63

4.5

37.41

38.17

mmol/mol

12.66

5732

50865

Undetermined asthma

4904

43279

1.76

57.58

6.4

5.2

40.10

39.08

mmol/mol

10.59

4582

40060

Fentanyl

2404

29429

0.60

57.56

6.7

6.0

43.20

40.43

mmol/mol

19.58

2109

26561

Other specified and unspecified personality disorders

3331

28586

2.02

57.36

7.0

4.7

39.59

38.57

mmol/mol

6.14

3156

26979

Other and unspecified tonsillitis

13914

108617

1.31

57.15

4.7

4.3

38.55

38.12

mmol/mol

5.79

13226

103246

Alcoholic liver disease

2488

29391

0.57

57.10

8.2

6.0

41.05

40.48

mmol/mol

1.58

2282

27217

Speech and linguistic disorders, excluding more controls

2550

19076

1.75

57.07

5.1

3.7

37.81

37.25

mmol/mol

1.72

2416

18075

Haemorrhoids and perianal venous thrombosis

11201

103036

1.40

56.91

6.4

5.9

39.76

40.23

mmol/mol

6.26

10297

93961

Other bacterial diseases

42072

278515

1.19

56.81

7.4

5.4

42.14

39.34

mmol/mol

307.65

39013

258341

Nutritional anaemias

18262

166116

1.28

56.74

7.6

5.9

41.76

39.89

mmol/mol

93.40

16648

152335

Nausea and vomiting

9968

89115

1.39

56.40

7.4

5.4

41.86

39.42

mmol/mol

72.86

9224

81873

Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

2743

23203

2.19

56.18

6.4

3.9

40.54

37.31

mmol/mol

47.32

2640

22145

Acute and transient psychotic disorders

4357

38300

1.83

56.02

7.2

4.9

39.48

39.02

mmol/mol

2.34

4095

36056

Heart failure and coronary heart disease

9480

77578

0.74

55.87

9.4

6.6

46.57

40.70

mmol/mol

307.65

8754

69369

Superficial injury of head

8203

74171

1.46

55.83

5.9

5.4

39.80

39.49

mmol/mol

2.03

7581

68794

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

11278

103555

1.37

55.31

5.9

4.6

38.77

38.28

mmol/mol

5.69

10464

97815

Retinal vascular occlusion

3866

33586

1.85

55.19

7.7

6.3

42.15

40.55

mmol/mol

18.55

3522

30343

Care involving dialysis

2668

22733

2.34

55.10

16.7

5.7

43.07

40.02

mmol/mol

28.23

2642

21014

Benign neoplasm: Colon, unspecified

8562

78309

1.55

54.92

8.0

6.5

41.41

40.68

mmol/mol

9.01

7843

71674

Other shoulder lesions

3415

29572

2.01

54.85

6.2

5.0

39.82

39.01

mmol/mol

5.05

3210

27557

In situ neoplasms

13299

118096

1.37

54.49

6.1

5.9

39.58

39.81

mmol/mol

2.36

12076

108674

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

22752

211263

1.25

54.39

5.2

5.0

38.23

38.68

mmol/mol

11.54

21289

197492

Acute appendicitis, no complications

23914

225884

1.25

53.90

5.3

5.1

39.19

39.03

mmol/mol

1.86

22611

212144

Other diseases of pleura

14337

136547

0.79

53.73

7.1

6.4

41.95

40.64

mmol/mol

38.64

12857

124637

Adhesive capsulitis of shoulder

6438

58447

1.66

53.65

7.8

5.6

43.48

39.74

mmol/mol

110.42

6055

53832

Disorders of ocular muscles, binocular movement, accommodation and refraction

18510

172071

1.27

53.59

5.6

5.1

39.13

38.85

mmol/mol

3.36

17276

160922

L01XE Protein kinase inhibitors

1314

16106

0.46

53.57

5.7

6.2

40.29

40.38

mmol/mol

0.12

1176

14797

Polyneuropathies and other disorders of the peripheral nervous system

7424

67572

1.55

53.45

9.1

6.2

43.94

40.43

mmol/mol

95.56

6958

61959

Other and unspecified effects of external causes

10214

93612

1.39

53.36

5.7

4.9

39.07

38.66

mmol/mol

3.95

9562

87803

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

14578

135057

1.30

53.20

5.3

4.6

38.77

38.27

mmol/mol

8.13

13643

127449

Allergic conjunctivitis

23638

220147

1.24

53.19

5.2

5.0

38.27

38.69

mmol/mol

10.49

22112

205805

Emotional disorders starting during childhood or adolescence

1465

10761

2.05

53.10

4.2

3.1

36.84

35.91

mmol/mol

2.37

1348

10199

Hypotension

5140

45261

1.59

53.02

8.0

6.5

42.57

41.02

mmol/mol

18.01

4661

40811

Glomerular diseases

6273

56482

1.59

52.93

12.8

5.7

45.84

39.94

mmol/mol

194.65

6052

52292

Ulcer of lower limb, not elsewhere classified

4540

40134

1.76

52.86

11.4

6.2

48.82

40.60

mmol/mol

219.09

4285

36505

Ovarian dysfunction

2552

21151

1.94

52.49

5.2

3.7

37.96

36.70

mmol/mol

10.34

2445

20013

Redundant prepuce, phimosis and paraphimosis

7540

67648

1.45

52.35

7.0

5.2

42.65

39.85

mmol/mol

67.62

7124

63861

Benign neoplasm: Sigmoid colon

6221

56600

1.69

51.86

7.6

6.3

40.87

40.54

mmol/mol

2.10

5799

51757

Acute appendicitis

30765

276836

1.21

51.81

5.4

5.3

39.36

39.18

mmol/mol

2.85

28978

259038

Fever of other and unknown origin

23014

201276

1.23

51.54

6.5

5.3

40.35

39.31

mmol/mol

46.01

21454

186173

Sequelae with surgical and medical care as external cause

6955

63469

1.60

51.51

6.8

6.0

40.60

40.02

mmol/mol

5.24

6551

58384

Fracture of lower leg, including ankle

22796

215244

1.25

51.36

6.3

5.5

40.58

39.51

mmol/mol

41.35

21196

199553

Malignant neoplasm of pancreas

1233

15949

0.52

51.30

7.6

6.5

46.27

40.95

mmol/mol

37.45

1124

14437

Serous carcinoma of ovary

757

9761

0.38

51.30

5.0

6.0

39.89

39.79

mmol/mol

0.07

677

8904

Ganglion

8393

76756

1.47

51.26

5.4

4.9

38.69

38.79

mmol/mol

0.52

7912

71552

Keratitis

13597

126840

1.34

51.19

6.2

5.4

40.33

39.38

mmol/mol

21.37

12678

118031

COPD/asthma/ILD related infections

52483

252890

1.15

51.16

6.0

5.2

39.98

38.95

mmol/mol

91.83

48797

235133

COPD/asthma related infections

52483

252890

1.15

51.16

6.0

5.2

39.98

38.95

mmol/mol

91.83

48797

235133

Retinal vascular disorders

3915

34151

1.77

51.12

7.7

6.3

42.17

40.57

mmol/mol

18.55

3563

30846

Injuries to the abdomen, lower back, lumbar spine and pelvis

14600

134980

1.30

51.07

6.0

5.7

39.99

39.72

mmol/mol

2.35

13428

124529

Secondary uncertain malignant neoplasm

3139

36585

0.63

50.91

5.8

6.3

41.02

40.54

mmol/mol

1.39

2791

33419

Malignant neoplasm of ovary

1031

12953

0.44

50.90

5.0

5.9

39.78

39.73

mmol/mol

0.04

914

11852

Lesion of ulnar nerve

5051

45287

1.73

50.68

6.8

5.4

40.94

39.46

mmol/mol

19.56

4749

42199

Unspecified/other endometriosis

3312

28213

1.75

50.58

4.3

4.1

36.85

37.57

mmol/mol

6.00

3105

26621

Viral infections characterized by skin and mucous membrane lesions

16047

150251

1.30

50.45

6.4

5.4

40.02

39.41

mmol/mol

11.96

14965

139889

Other enthesopathy of foot (+metatarsalgia)

3721

32738

1.92

50.36

6.2

5.1

39.34

39.06

mmol/mol

1.12

3477

30325

Hallux rigidus

5176

46626

1.74

50.32

6.2

5.8

39.11

40.22

mmol/mol

16.21

4672

42332

Other ill-defined and unspecified causes of mortality

1160

15175

0.52

50.09

6.1

6.5

44.18

41.25

mmol/mol

11.50

968

13777

Plantar fascial fibromatosis

3622

32002

2.00

49.66

6.4

5.1

39.69

39.19

mmol/mol

2.87

3392

29726

Diseases of salivary glands

7254

65970

1.50

49.43

6.2

5.3

39.76

39.42

mmol/mol

2.33

6739

61201

Abrasion of teeth

10988

75356

1.45

49.32

5.7

5.3

38.55

39.16

mmol/mol

12.47

10203

70941

Other disorders of glucose regulation and pancreatic internal secretion

2802

23768

1.91

49.30

12.6

5.4

53.09

39.54

mmol/mol

277.21

2662

22059

Disorders of breast

19603

172026

1.28

49.12

5.4

5.1

38.58

38.71

mmol/mol

1.38

18340

159681

Other CVD

6115

54769

1.51

48.91

7.9

6.4

42.27

40.88

mmol/mol

18.28

5561

49546

Allergic rhinitis

11971

109458

1.32

48.86

4.9

4.5

38.21

38.16

mmol/mol

0.27

11246

103342

Left bundle-branch block

2437

20756

2.24

48.74

7.2

6.0

41.09

40.09

mmol/mol

6.04

2206

18839

Cervicocranial syndrome

3963

34983

1.81

48.68

5.9

5.3

39.10

39.34

mmol/mol

0.98

3754

32275

Extrapyramidal and movement disorders

13323

124554

1.34

48.60

6.7

6.1

40.08

40.25

mmol/mol

1.26

12260

113932

All influenza

9352

85876

1.40

48.52

6.9

5.5

41.49

39.52

mmol/mol

53.51

8732

79546

Benign neoplasm: Rectum

6024

54973

1.68

48.38

7.3

6.3

40.74

40.52

mmol/mol

1.05

5624

50289

Leisure time condition

6188

55764

1.53

48.34

6.2

5.4

40.04

39.38

mmol/mol

5.64

5713

51809

Asthma and allergy, excluding more controls

5155

44771

1.50

48.08

4.7

4.0

38.01

37.54

mmol/mol

2.54

4900

42299

Lateral epicondylitis

5190

46874

1.71

47.97

6.0

5.0

39.72

39.10

mmol/mol

4.35

4926

43874

Disorders of psychological development

3699

28950

1.53

47.72

4.9

3.7

37.55

37.13

mmol/mol

1.56

3480

27394

Asthma and allergy

5154

44788

1.50

47.69

4.7

4.0

38.01

37.61

mmol/mol

1.97

4899

42343

Polycystic ovarian syndrome, broad definition

3763

32398

1.62

47.38

4.6

3.5

37.24

36.43

mmol/mol

8.01

3630

30783

Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)

839

11556

0.49

47.26

6.0

6.5

41.64

41.16

mmol/mol

0.65

721

10529

Thyrotoxicosis with diffuse goitre

5106

45812

1.64

47.10

5.8

4.9

39.51

38.65

mmol/mol

8.03

4755

42704

Sequelae of external causes of morbidity and mortality

8929

82401

1.44

47.04

6.7

5.8

40.50

39.90

mmol/mol

6.81

8417

75912

Pre-eclampsia or eclampsia

8083

74204

1.46

46.87

6.4

4.6

40.62

37.91

mmol/mol

100.50

7666

69576

Metatarsalgia

3434

30218

1.93

46.80

6.3

5.1

39.40

39.10

mmol/mol

1.13

3205

27973

Benign neoplasm: Rectum, anus and anal canal

6839

62687

1.57

46.77

7.2

6.3

40.77

40.50

mmol/mol

1.53

6367

57299

Pain associated with micturition

3983

35161

1.75

46.70

6.8

5.6

39.84

39.54

mmol/mol

1.17

3623

32443

Ventral hernia

8697

80213

1.45

46.60

7.3

6.0

41.04

40.20

mmol/mol

12.86

8076

73647

Benign neoplasm: Sigmoid colon

6221

56969

1.64

46.15

7.6

6.4

40.87

40.60

mmol/mol

1.58

5799

52260

Adenocarcinoma of pancreas, excluding all cancers (controls excluding all cancers)

455

6691

0.38

46.12

6.9

6.7

45.79

41.08

mmol/mol

11.31

408

6122

Lichen ruber planus, wide definition including periferal and oral lichen planus

7532

69683

1.57

46.00

6.4

5.9

39.86

39.85

mmol/mol

0.04

6967

64234

Other problems related to primary support group, including family circumstances

3887

32800

1.59

45.89

6.0

4.2

39.18

37.73

mmol/mol

12.88

3668

31016

Degenerative macular diseases

3979

35208

1.75

45.85

7.5

6.3

41.68

40.44

mmol/mol

11.46

3565

31790

Small cell lung cancer, helper endpoint

308

5380

0.36

45.81

5.6

6.5

42.52

41.29

mmol/mol

1.16

260

4840

Small cell lung cancer

308

5380

0.36

45.81

5.6

6.5

42.52

41.29

mmol/mol

1.16

260

4840

Other gastritis (incl. Duodenitis)

8379

77093

1.44

45.65

7.7

5.8

41.40

40.11

mmol/mol

24.64

7854

70634

Benign lipomatous neoplasm

11047

103241

1.40

45.42

6.3

5.8

39.88

mmol/mol

0.01

10280

95487

Adenocarcinoma of pancreas

455

6676

0.38

45.37

6.9

6.5

45.79

40.90

mmol/mol

12.12

408

6065

Injuries to the thorax

17051

160605

1.27

45.22

6.5

5.8

40.59

39.99

mmol/mol

10.90

15630

148532

Amenorrhoea

2388

19746

1.79

45.14

5.5

3.8

38.64

37.06

mmol/mol

10.62

2264

18643

Faecal incontinence

3169

28027

2.09

45.04

6.7

5.8

40.11

39.87

mmol/mol

0.76

2876

25541

Polymyalgia rheumatica

4247

37806

1.70

44.75

7.8

6.5

41.78

40.91

mmol/mol

7.77

3903

33982

Benign neoplasm: Ascending colon

4267

38481

1.86

44.73

7.9

6.4

41.11

40.58

mmol/mol

3.04

4027

35133

Other disorders of kidney and ureter

4240

37936

1.76

44.63

9.2

6.1

41.11

40.28

mmol/mol

6.09

4048

34907

Pre-eclampsia

7467

68403

1.46

44.51

6.3

4.5

40.53

37.81

mmol/mol

92.97

7082

64234

Carbimazole or st.post thyroidectomy, condition for graves disease

7544

69456

1.50

44.50

5.8

5.3

39.41

39.01

mmol/mol

3.19

7021

64634

Fissure and fistula of anal and rectal regions

9545

88455

1.40

44.44

6.3

5.4

39.60

39.66

mmol/mol

0.24

8835

81991

Thoracic aortic aneurysm

4549

41095

1.78

44.27

6.3

6.4

39.19

40.54

mmol/mol

25.28

4139

37665

Abnormal involuntary movements

4543

40695

1.68

44.09

6.4

5.6

39.44

39.64

mmol/mol

0.79

4271

37625

Osteopathies and chondropathies

21867

197173

1.24

44.04

6.6

5.7

40.38

39.69

mmol/mol

17.81

20153

182019

Female infertility, associated with anovulation

2769

23259

1.69

43.91

4.3

3.4

36.97

36.55

mmol/mol

2.00

2680

22172

Small cell lung cancer, excluding all cancers (controls excluding all cancers)

308

5329

0.37

43.77

5.6

6.7

42.52

41.42

mmol/mol

0.99

260

4833

Hypertensive Heart Disease

8182

60917

1.37

43.73

9.5

5.2

45.02

39.11

mmol/mol

303.80

7430

54305

Glomerular disorders in diseases classified elsewhere

3839

34046

1.75

43.44

16.2

5.7

49.85

39.97

mmol/mol

258.05

3712

31498

Conjunctivitis (acute, non atopic)

10277

94850

1.35

43.43

5.9

5.1

39.50

38.97

mmol/mol

6.23

9612

88711

Female infertility

12505

71609

1.29

43.35

4.4

4.3

37.36

37.88

mmol/mol

10.40

11880

67205

Adenocarcinoma and ductal carcinoma of pancreas

624

8490

0.43

43.34

7.0

6.5

45.34

40.83

mmol/mol

14.65

571

7708

Ptosis of eyelid

3600

32155

1.93

43.28

7.0

6.2

40.52

40.37

mmol/mol

0.45

3357

29386

Benign neoplasm of other and unspecified endocrine glands

4400

39726

1.78

43.25

7.2

5.8

40.63

39.74

mmol/mol

8.15

4166

36745

Unspecified fall

18745

175561

1.24

43.25

6.1

5.6

40.03

39.65

mmol/mol

5.20

17020

162342

Other and unspecified vascular occlusions

2952

25631

1.86

42.93

7.5

6.3

41.91

40.59

mmol/mol

10.12

2672

23164

Substance use, excluding alcohol

7254

66267

1.44

42.85

6.4

4.9

39.70

38.87

mmol/mol

6.98

6602

62452

Gestational [pregnancy-induced] hypertension

9493

87479

1.36

42.58

5.2

4.2

38.95

37.38

mmol/mol

53.36

9080

82525

Other bursopathies

4729

42620

1.65

42.26

6.5

5.6

40.06

39.86

mmol/mol

0.77

4401

39199

Adenocarcinoma and ductal carcinoma of pancreas, excluding all cancers (controls excluding all cancers)

624

8465

0.43

42.23

7.0

6.6

45.34

41.04

mmol/mol

13.38

571

7739

Benign neoplasm: Rectum

6024

55372

1.62

42.23

7.3

6.4

40.74

40.57

mmol/mol

0.68

5624

50872

Other follicular disorders

2440

20958

2.02

42.13

7.2

4.9

40.51

38.73

mmol/mol

12.56

2304

19725

Other and unspecified visual disturbances

3193

28213

1.92

42.06

6.2

5.6

39.52

39.55

mmol/mol

0.07

2997

26150

Adenomyosis (Endometriosis of uterus)

4886

44139

1.63

41.89

5.7

5.2

38.87

39.21

mmol/mol

2.15

4553

40703

Benign neoplasm: Skin of eyelid, including canthus

5272

48009

1.64

41.84

6.6

6.0

40.16

40.09

mmol/mol

0.24

4842

44061

Psoriasis

10765

100666

1.37

41.79

6.7

5.6

40.59

39.61

mmol/mol

15.81

10044

93648

Injuries to the ankle and foot

29407

256150

1.18

41.71

5.7

5.0

39.43

38.79

mmol/mol

21.85

27490

240383

Psychotic depression

2172

18197

1.92

41.64

6.5

4.8

39.63

39.01

mmol/mol

2.00

2016

17020

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

5571

59585

0.68

41.63

6.0

40.52

39.81

mmol/mol

6.19

5051

54492

Other disorders starting during childhood or adolecense, excluding more controls

1346

9714

1.84

41.62

4.1

2.9

36.54

36.14

mmol/mol

0.70

1288

9266

Benign neoplasm: Rectum, anus and anal canal

6839

63055

1.53

41.62

7.2

6.4

40.77

40.57

mmol/mol

0.95

6367

57876

Urolithiasis

11750

109834

1.33

41.60

7.1

6.1

41.21

40.29

mmol/mol

16.26

10895

101300

Chronic laryngitis and laryngotracheitis

5009

45345

1.62

41.45

6.9

5.7

39.89

39.80

mmol/mol

0.26

4473

41934

Monoamine oxidase A inhibitors

4425

39830

1.69

41.43

6.8

5.4

39.71

39.61

mmol/mol

0.33

4109

36977

Injuries to the elbow and forearm

29140

251930

1.18

41.38

5.5

5.4

39.15

39.26

mmol/mol

1.18

26848

233985

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

5849

52792

1.47

41.30

5.3

4.5

38.06

37.79

mmol/mol

1.40

5448

49484

Hypertensive heart and/or renal disease

9219

65620

1.34

41.15

9.7

5.1

44.74

39.06

mmol/mol

307.65

8430

58612

Other symptoms and signs involving the urinary system

3426

30176

1.75

41.01

7.4

5.9

40.51

40.22

mmol/mol

1.00

3284

27793

Other inflammation of eyelid

4470

40237

1.66

40.85

6.4

5.6

39.41

39.61

mmol/mol

0.75

4106

37177

Eating disorder

2864

24173

1.61

40.76

5.0

3.6

37.41

36.46

mmol/mol

4.47

2666

22892

Coronary angioplasty

14268

103259

1.31

40.64

8.4

6.1

44.22

40.16

mmol/mol

307.65

13324

93205

Benign neoplasm of other and ill-defined parts of digestive system

6109

56174

1.58

40.53

7.7

6.0

41.04

40.09

mmol/mol

11.84

5735

51561

Open wound of wrist and hand

17404

162894

1.24

40.30

5.4

5.3

39.19

39.27

mmol/mol

0.53

16137

152846

Recurring oral aphthae, including avohilmo

4611

41478

1.60

40.13

6.3

5.5

39.30

39.34

mmol/mol

0.10

4268

38350

Nontoxic multinodular goitre

7177

66377

1.50

40.00

6.6

5.7

40.13

39.67

mmol/mol

3.87

6637

60585

Benign neoplasm: Ascending colon

4267

38771

1.79

39.65

7.9

6.5

41.11

40.70

mmol/mol

2.01

4027

35531

Abnormal results of function studies

2909

25572

1.90

39.56

6.6

5.5

40.27

39.50

mmol/mol

3.62

2701

23806

Other disorders of fluid, electrolyte and acid-base balance

10711

96162

1.32

39.56

8.3

5.7

42.57

39.82

mmol/mol

103.17

9828

87129

Other symptoms and signs involving the circulatory and respiratory systems

2240

19101

1.97

39.50

7.3

5.2

40.17

39.33

mmol/mol

3.77

2080

17648

Certain disorders involving the immune mechanism

6861

63244

1.49

39.38

7.3

5.5

40.52

39.59

mmol/mol

11.97

6525

58853

Deposits [accretions] on teeth

2320

19022

1.86

39.38

8.0

5.0

39.01

39.35

mmol/mol

0.85

2186

17759

Hypoglycaemia, other or unspecified

2199

18629

1.92

39.32

12.1

5.4

51.88

39.43

mmol/mol

190.20

2095

17294

Other metabolic disorders

4698

42438

1.61

39.27

6.3

4.8

39.84

38.48

mmol/mol

18.65

4441

39364

Adverse effects, not elsewhere classified

6968

63802

1.42

39.03

5.9

5.0

39.09

38.68

mmol/mol

3.13

6517

59621

Brachial plexus disorders

3356

29745

1.77

39.03

5.2

4.5

38.77

38.31

mmol/mol

2.47

3216

28063

Special screening examination for infectious and parasitic diseases

11086

76528

1.27

38.81

4.1

3.6

36.37

37.41

mmol/mol

27.80

10397

72660

Injuries to the neck

8206

75598

1.37

38.80

5.5

5.1

38.86

38.93

mmol/mol

0.23

7622

70904

Localized swelling, mass and lump of skin and subcutaneous tissue

11699

109730

1.32

38.77

6.1

5.6

39.54

39.67

mmol/mol

0.74

10942

101492

Leiomyoma of uterus

20409

109657

1.25

38.76

5.5

5.0

38.94

38.69

mmol/mol

4.09

18841

102978

Atherosclerosis, excluding cerebral and coronary sclerosis

13149

112096

0.81

38.72

9.5

6.5

45.91

40.78

mmol/mol

307.65

12070

101215

Use of disulfiram, acamprosate or naltrexone

3124

27837

1.93

38.51

6.8

5.2

39.41

39.54

mmol/mol

0.32

2907

26392

Abnormalities of gait and mobility

3778

33703

1.68

38.47

7.3

6.3

41.34

40.48

mmol/mol

5.25

3483

30702

Suicide or other Intentional self-harm

9255

85785

1.34

38.41

6.4

4.9

39.46

38.72

mmol/mol

9.07

8547

80805

L02BA Anti-estrogens

4980

54431

0.69

38.39

4.8

5.5

38.95

39.31

mmol/mol

2.71

4578

50334

Achilles tendinitis

3810

34278

1.76

38.29

6.5

5.4

39.73

39.66

mmol/mol

0.16

3573

31788

Speech therapy

9849

92168

1.38

38.19

7.8

5.8

40.87

39.86

mmol/mol

20.05

9619

84806

Transport accidents

20165

169516

1.21

37.98

5.4

5.0

39.09

38.98

mmol/mol

0.91

18854

159050

Other and unspecified urticaria

7039

64612

1.41

37.97

5.8

5.0

39.17

38.76

mmol/mol

3.06

6538

60445

Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)

1131

14090

0.54

37.81

4.7

5.7

39.22

39.94

mmol/mol

1.83

1051

13125

Other disorders of bladder

3969

35515

1.64

37.76

7.1

6.2

40.38

40.44

mmol/mol

0.14

3504

32510

Idiopathic gout

2817

24772

1.88

37.65

8.9

6.5

42.74

40.97

mmol/mol

16.59

2665

22626

Benign neoplasm: Transverse colon

3232

29001

1.95

37.63

8.4

6.4

41.50

40.58

mmol/mol

6.20

3044

26514

Malignant neoplasm of oesophagus

430

6114

0.40

37.48

5.5

6.5

40.47

41.06

mmol/mol

0.73

378

5581

Ascites

1823

21307

0.58

37.32

7.6

5.9

42.00

40.22

mmol/mol

6.26

1689

19558

Problems related to lifestyle

3692

32708

1.61

37.08

6.7

4.7

40.29

38.57

mmol/mol

16.25

3452

30698

Agoraphobia

1076

8401

2.45

37.04

5.6

3.8

37.95

37.58

mmol/mol

0.52

1000

8006

Preparatory care for dialysis

1373

11616

3.32

37.03

16.4

6.0

43.17

40.30

mmol/mol

13.53

1367

10770

Calculus of kidney and ureter

10848

101602

1.32

36.99

7.1

6.0

41.19

40.24

mmol/mol

15.60

10084

93779

Eating disorders

3523

30611

1.51

36.71

5.3

4.0

38.24

37.13

mmol/mol

6.98

3281

28870

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

1736

20632

0.60

36.65

5.1

5.8

39.50

40.10

mmol/mol

1.98

1611

19112

Inflammatory disease of uterus

5006

45265

1.50

36.56

5.1

4.5

37.85

37.89

mmol/mol

0.11

4686

42532

Any event in hilmo or specialist outpatient

447

1440

2.92

36.46

4.6

2.7

39.12

36.75

mmol/mol

5.46

428

1379

Rheumatoid arthritis

12817

109430

1.28

36.44

5.7

5.5

38.88

39.80

mmol/mol

22.03

11958

100162

Superficial injury of wrist and hand

7049

64562

1.37

36.34

5.4

4.8

38.86

38.60

mmol/mol

1.36

6566

60636

Lichen planus, including avohilmo

6381

59193

1.54

36.24

6.5

5.9

39.98

39.90

mmol/mol

0.28

5893

54522

Benign neoplasm of other and unspecified endocrine glands

4400

40158

1.70

36.07

7.2

5.9

40.63

39.83

mmol/mol

6.66

4166

37300

Unspecified urinary incontinence

2950

26155

1.84

36.01

7.9

5.8

41.15

39.77

mmol/mol

9.62

2471

23925

Dislocation, sprain and strain of joints and ligaments at neck level

5327

48264

1.46

35.97

5.2

4.7

38.46

38.43

mmol/mol

0.09

4993

45452

Endometriosis of ovary

6405

58536

1.42

35.92

4.9

4.8

38.30

38.56

mmol/mol

1.52

5929

54521

Otitis externa, unspecified

3667

32713

1.64

35.72

6.7

5.2

40.33

39.08

mmol/mol

11.26

3427

30639

Mixed conductive and sensorineural hearing loss

4105

36972

1.61

35.61

6.7

6.1

40.52

40.31

mmol/mol

0.75

3704

33882

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

19377

127268

1.24

35.60

6.5

6.4

40.05

40.54

mmol/mol

10.06

17481

116650

TMD related operations

5969

54831

1.48

35.52

5.5

5.0

38.12

38.82

mmol/mol

9.12

5683

51594

Missing teeth due to accident, extraction or parodontitis

4015

36291

1.67

35.49

7.5

5.6

40.41

39.90

mmol/mol

2.53

3776

33515

Persons with potential health hazards related to communicable diseases

14520

135288

1.23

35.48

5.0

4.5

37.79

38.04

mmol/mol

2.57

13593

128016

Benign lipomatous neoplasm

11047

104166

1.34

35.45

6.3

5.9

39.88

39.96

mmol/mol

0.35

10280

96668

Striking against or struck by other objects

12151

113822

1.27

35.44

5.4

5.1

39.17

39.06

mmol/mol

0.59

11244

106955

Emergency coronary revascularization (for ACS)

20485

140233

1.21

35.40

8.5

6.4

44.37

40.59

mmol/mol

307.65

19095

127263

Non-Hodgkin lymphoma, all

721

9588

0.50

35.33

5.3

6.6

41.04

41.16

mmol/mol

0.11

631

8690

Familial hypercholesterolemia, with ischemic heart disease

3064

27155

1.76

35.22

10.2

6.2

45.14

40.40

mmol/mol

90.50

2809

24260

Hidradenitis suppurativa

1229

10073

2.64

35.19

7.1

4.5

40.93

38.30

mmol/mol

12.67

1166

9550

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

4225

46569

0.69

35.18

6.0

6.3

40.73

40.47

mmol/mol

1.00

3862

42939

Mycoses

9408

87903

1.35

35.16

7.0

5.6

40.79

39.59

mmol/mol

21.20

8726

81429

Benign neoplasm: Skin of eyelid, including canthus

5272

48457

1.57

35.16

6.6

6.1

40.16

40.18

mmol/mol

0.06

4842

44569

Disorders of refraction and accommodation

9547

88351

1.31

35.13

5.3

4.9

38.50

38.62

mmol/mol

0.62

8909

82907

Vitreous haemorrhage

3287

29335

1.74

35.10

11.7

5.9

50.30

40.13

mmol/mol

203.90

3083

27038

Coronary revascularization (ANGIO or CABG)

18001

119646

1.25

35.07

8.5

6.0

44.32

40.10

mmol/mol

307.65

16827

108350

Alzheimer disease

7655

63249

0.79

35.06

6.3

7.0

42.69

41.53

mmol/mol

14.34

6530

56516

Carcinoma in situ of skin

2420

21250

1.98

34.80

7.1

6.6

40.26

40.98

mmol/mol

3.84

2217

19212

Implicit Sepsis

30475

227756

1.17

34.79

7.6

5.7

41.83

39.64

mmol/mol

210.24

28140

209814

Other disorders of eye and adnexa

4747

43014

1.52

34.72

6.1

5.2

39.33

39.03

mmol/mol

1.20

4463

40062

Dissociative [conversion] disorders

1295

10486

2.21

34.60

5.8

4.4

38.57

37.95

mmol/mol

1.38

1214

9865

Diplopia

4384

39737

1.58

34.55

6.7

5.7

40.36

39.81

mmol/mol

3.05

4086

36724

Diabetic nephropathy

4543

48363

0.65

34.53

17.7

11.6

57.61

49.06

mmol/mol

258.84

4363

45379

Symptoms and signs concerning food and fluid intake

3477

30818

1.60

34.31

6.7

5.6

39.59

39.61

mmol/mol

0.04

3210

28299

Impacted cerumen

3070

27199

1.72

34.29

7.1

6.2

40.27

40.42

mmol/mol

0.35

2463

24949

Psoriasis vulgaris

6720

62209

1.44

34.14

6.9

5.5

40.72

39.64

mmol/mol

14.52

6283

57998

Nephropathy related operations

4025

36401

1.62

33.97

14.7

5.8

42.52

40.12

mmol/mol

28.66

3966

33722

Postprocedural endocrine and metabolic disorders, not elsewhere classified

4299

38974

1.58

33.78

6.2

4.8

39.72

38.46

mmol/mol

15.08

4066

36165

Other disorders of penis

3137

27697

1.64

33.73

7.4

5.7

41.99

40.35

mmol/mol

12.31

2916

25861

Human immunodeficiency virus [HIV] disease resulting in other conditions

622

4841

8.67

33.62

8.5

4.9

35.25

39.29

mmol/mol

33.19

622

4622

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

1946

22814

0.63

33.56

7.8

6.6

45.16

41.01

mmol/mol

40.97

1783

20781

Dialysis, with operation codes

4229

38361

1.59

33.40

14.4

5.7

42.69

39.98

mmol/mol

37.37

4162

35506

Anosmia

868

6757

3.14

33.34

6.1

3.0

38.79

36.72

mmol/mol

11.63

799

6099

Malignant neoplasm, without specification of site

500

7159

0.48

33.34

6.0

6.4

41.83

41.16

mmol/mol

0.72

422

6450

Disorders resulting from impaired renal tubular function

1135

9467

3.25

33.15

14.6

5.9

42.74

40.16

mmol/mol

10.53

1116

8772

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

7616

78004

0.74

33.09

5.4

5.9

39.20

39.65

mmol/mol

4.23

6819

71617

Other peripheral vertigo

3043

27295

1.83

33.08

6.4

5.9

39.84

40.02

mmol/mol

0.53

2751

25116

Other disorders of skin and subcutaneous tissue, not elsewhere classified

4865

44335

1.50

32.92

8.2

5.8

42.42

39.87

mmol/mol

41.51

4413

40759

Mixed disorders of conduct and emotions, excluding more controls

669

4651

2.24

32.89

4.4

2.6

37.29

35.77

mmol/mol

2.57

631

4449

Other female pelvic inflammatory diseases

5906

54622

1.49

32.88

6.0

5.2

39.03

38.79

mmol/mol

1.32

5327

50623

Type 1 diabetes, wide definition, subgroup 2

205

3760

0.37

32.87

12.7

3.8

55.87

37.01

mmol/mol

49.09

192

3367

Benign neoplasm of other and ill-defined parts of digestive system

6109

56749

1.50

32.60

7.7

6.1

41.04

40.21

mmol/mol

9.31

5735

52234

Malignant neoplasm of oesophagus, excluding all cancers (controls excluding all cancers)

756

9622

0.50

32.56

5.8

6.6

41.02

41.05

mmol/mol

0.04

681

8849

Benign neoplasm: Transverse colon

3232

29288

1.86

32.39

8.4

6.5

41.50

40.70

mmol/mol

4.84

3044

26872

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

18972

125154

1.23

32.28

6.5

6.4

40.09

40.56

mmol/mol

8.93

17105

114674

Other eating disorders

1592

12984

1.77

32.24

5.6

3.5

38.20

36.54

mmol/mol

6.00

1489

12316

Malignant neoplasm of eye, brain and central nervous system

934

11630

0.53

32.08

4.7

5.7

39.24

39.94

mmol/mol

1.49

869

10757

Pruritus

3677

33003

1.58

32.05

7.0

5.4

40.28

39.30

mmol/mol

7.10

3433

30474

Adenocarcinoma and papillary adenocarcinoma of stomach

465

6643

0.47

32.04

6.3

6.4

41.32

41.05

mmol/mol

0.21

417

6024

Spontaneous rupture of synovium and tendon

2805

25023

1.82

32.00

6.7

5.6

40.28

39.85

mmol/mol

1.72

2597

22956

Hydrocele

3820

33856

1.46

31.96

6.8

6.2

40.84

40.93

mmol/mol

0.21

3541

31216

Speech and linguistic disorders

2585

21041

1.51

31.93

5.1

3.9

37.74

37.31

mmol/mol

1.19

2451

19855

Psoriatic arthropathies

3661

33018

1.62

31.84

6.3

5.2

40.01

39.49

mmol/mol

1.90

3426

30612

Appendectomy

27941

258930

1.17

31.80

5.3

5.2

39.08

39.00

mmol/mol

0.70

26230

242366

Atrophic disorders of skin

5007

46071

1.54

31.80

6.4

5.4

39.72

39.26

mmol/mol

3.25

4678

42532

Respiratory insufficiency

1952

22901

0.65

31.79

7.8

6.2

44.82

40.42

mmol/mol

45.68

1730

20695

Dental caries 3 and operation codes, only avohilmo

13976

66309

1.25

31.78

5.5

5.2

39.20

38.63

mmol/mol

9.84

13053

62269

Brain glioblastoma, excluding all cancers (controls excluding all cancers)

228

3397

0.31

31.70

4.0

6.2

40.40

40.25

mmol/mol

0.08

211

3146

Malignant neoplasm of brain

689

8893

0.49

31.57

4.3

5.6

39.12

39.74

mmol/mol

0.92

635

8275

Melanocytic naevi

10724

100863

1.29

31.36

5.8

5.3

38.64

39.09

mmol/mol

5.97

10130

94026

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

17029

116209

0.82

31.36

5.3

5.5

39.30

39.18

mmol/mol

1.00

15424

108064

Carcinoma in situ of skin

2420

21429

1.91

31.33

7.1

6.7

40.26

41.07

mmol/mol

4.66

2217

19471

Other symptoms and signs involving the digestive system and abdomen

6132

56608

1.42

31.29

6.6

5.3

40.04

39.30

mmol/mol

6.28

5472

52207

Covid-19 suspected case

7572

70062

1.33

31.24

7.2

4.7

39.86

38.34

mmol/mol

31.07

7164

65949

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

17027

116187

0.82

31.23

5.3

5.5

39.30

39.18

mmol/mol

1.01

15422

108043

Malignant neoplasm of other and unspecified female genital organs, excluding all cancers (controls excluding all cancers)

627

7681

0.41

31.22

5.0

6.3

39.49

40.05

mmol/mol

0.97

570

7038

Short stature, not elsewhere classified

545

3391

2.30

31.12

4.0

3.0

33.87

36.28

mmol/mol

10.48

530

3195

Other noninflammatory disorders of vulva and perineum

3159

28007

1.59

31.11

5.8

4.7

38.39

38.54

mmol/mol

0.42

2940

26046

Benign neoplasm: Caecum

3232

29315

1.81

31.04

7.9

6.4

41.30

40.59

mmol/mol

3.90

3035

26709

Ocular pain

2671

23660

1.75

30.88

6.3

5.1

39.41

38.90

mmol/mol

1.78

2509

22082

Female infertility, cervigal, vaginal, other or unspecified origin

11130

69718

1.26

30.83

4.3

37.22

37.91

mmol/mol

16.99

10554

65457

Gingival hyperplasia

1044

8485

2.57

30.80

8.2

5.3

39.62

39.61

mmol/mol

0.01

983

7870

Chronic diseases of tonsils and adenoids

36999

226268

1.14

30.73

5.0

5.1

38.55

39.01

mmol/mol

18.59

34983

211570

Memory loss

2904

25923

1.73

30.70

6.6

6.5

40.02

40.66

mmol/mol

3.12

2711

23558

Fracture of foot, except ankle

8789

82076

1.31

30.57

6.0

5.0

39.84

38.89

mmol/mol

13.19

8209

76937

Diseases of the digestive system

16915

160361

1.20

30.44

7.2

5.9

41.30

40.05

mmol/mol

40.67

15581

147178

Nontoxic goitre/thyroid nodule

10968

103963

1.32

30.31

6.3

5.9

40.00

39.76

mmol/mol

1.79

10173

95128

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

19738

129736

1.22

30.28

6.6

6.4

40.20

40.53

mmol/mol

4.52

17836

118972

Persons encountering health services for specific procedures, not carried out

2571

22632

1.71

30.24

6.3

5.0

39.50

38.89

mmol/mol

2.02

2405

21140

Glaucoma, exfoliation

3349

29704

1.52

30.23

6.8

6.7

41.19

41.26

mmol/mol

0.17

2968

26527

Preparation and fitting of bite rail to mouth

4822

44233

1.50

30.13

5.5

5.0

38.10

38.83

mmol/mol

8.41

4616

41651

Normotensive glaucoma

2623

23477

1.87

30.12

6.6

40.59

40.72

mmol/mol

0.30

2293

21201

Mental disorders, not otherwise specified

2837

25052

1.63

30.11

6.1

4.5

39.16

38.22

mmol/mol

4.75

2713

23644

Adenocarcinoma and papillary adenocarcinoma of stomach, excluding all cancers (controls excluding all cancers)

465

6584

0.48

30.09

6.3

6.5

41.32

41.15

mmol/mol

0.12

417

6009

malignant neoplasm of female genital organs

4282

46580

0.70

30.04

6.1

6.0

40.78

39.91

mmol/mol

6.47

3854

42308

Fracture of rib(s), sternum and thoracic spine

10459

98430

1.28

30.01

6.7

6.0

40.89

40.29

mmol/mol

6.65

9543

90733

Infections with a predominantly sexual mode of transmission

11541

108384

1.24

29.96

5.3

4.4

38.53

37.94

mmol/mol

7.44

10795

102553

Single delivery by forceps and vacuum extractor

4419

29986

0.74

29.95

3.1

4.1

35.72

37.28

mmol/mol

41.26

4212

28664

Valvular operations

4881

44486

1.43

29.84

6.3

6.1

40.29

40.34

mmol/mol

0.15

4554

40344

Alzheimer’s disease (Early onset)

801

10611

0.57

29.79

5.7

6.4

42.74

41.38

mmol/mol

2.08

669

9502

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

3941

43322

0.71

29.79

9.2

6.1

42.59

40.50

mmol/mol

20.49

3665

40038

Oligomenorrhoea

1217

9954

2.11

29.70

6.3

4.2

39.45

37.80

mmol/mol

6.31

1154

9332

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

25152

224352

1.18

29.69

6.7

6.0

40.67

40.10

mmol/mol

15.91

23108

206238

Visual impairment including blindness (binocular or monocular)

2076

17852

1.73

29.68

8.2

5.9

42.31

40.30

mmol/mol

10.66

1776

16299

Major coronary heart disease event

28877

186144

1.17

29.43

8.3

6.0

43.41

40.06

mmol/mol

307.65

27203

169987

Sarcoidosis

4683

43148

1.54

29.43

7.1

5.6

41.06

39.71

mmol/mol

16.15

4437

40104

Influenza and pneumonia

48354

308687

1.12

29.32

6.4

5.2

40.82

38.96

mmol/mol

250.39

45049

287615

Brain glioblastoma and astrocytoma, excluding all cancers (controls excluding all cancers)

313

4393

0.37

29.24

3.8

5.9

39.22

39.96

mmol/mol

0.73

285

4087

Haemorrhage in early pregnancy

10427

95698

1.27

29.20

4.8

4.4

37.90

37.48

mmol/mol

6.37

9841

89928

Psoriatic and enteropathic arthropathies

4246

38766

1.52

29.03

6.2

5.1

39.76

39.37

mmol/mol

1.39

3988

35989

Parodontitis, operation under 40 years and operation codes

2889

25054

1.47

29.01

4.7

3.3

38.38

36.35

mmol/mol

16.25

2754

23917

41609

252575

1.12

28.86

6.5

5.2

40.91

38.95

mmol/mol

232.57

38674

234842

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

41609

252575

1.12

28.86

6.5

5.2

40.91

38.95

mmol/mol

232.57

38674

234842

Other disorders of conjunctiva

4708

43313

1.51

28.77

6.7

6.0

40.31

40.22

mmol/mol

0.27

4322

39831

Abnormal blood-pressure reading, without diagnosis

1535

13130

2.12

28.76

5.6

5.1

38.46

39.09

mmol/mol

2.38

1418

12138

Parodontitis, under 40 years and operation codes

2883

25019

1.46

28.69

4.6

3.3

38.37

36.36

mmol/mol

16.15

2749

23882

Erosion of teeth, including avohilmo

7496

67474

1.34

28.67

5.9

4.9

38.31

38.58

mmol/mol

1.74

6992

63779

Viral warts

3327

29835

1.56

28.66

6.9

5.1

39.94

38.85

mmol/mol

8.12

3166

27914

Malignant neoplasm of breast, HER-positive

11528

119165

0.79

28.62

5.4

5.8

39.54

39.58

mmol/mol

0.17

10441

109408

Retention of urine

11804

93856

1.23

28.62

7.4

6.3

41.95

40.73

mmol/mol

27.67

10700

85683

Cellulitis

7652

71371

1.33

28.51

7.7

5.4

42.79

39.46

mmol/mol

86.66

7106

66349

Palmar fascial fibromatosis [Dupuytren]

5286

48362

1.39

28.46

7.0

6.3

41.63

40.82

mmol/mol

6.46

4803

43865

Radiculopathy

5908

54511

1.38

28.45

6.8

5.8

40.71

40.10

mmol/mol

5.38

5500

49741

Acute pharyngitis

5202

46933

1.36

28.43

4.9

4.4

38.40

38.22

mmol/mol

0.72

4893

44458

Pilonidal cyst

3086

27505

1.57

28.39

6.0

4.4

40.79

38.36

mmol/mol

26.47

2942

26156

Brain glioblastoma

228

3349

0.33

28.35

4.0

6.1

40.40

40.35

mmol/mol

0.03

211

3093

Impotence

1707

14812

2.06

28.21

8.6

6.1

43.09

40.74

mmol/mol

14.12

1599

13765

Open wound of lower leg

4915

44956

1.42

28.20

6.2

5.5

40.25

39.54

mmol/mol

4.97

4549

41636

Strabismus

9540

89268

1.27

28.19

5.9

5.2

39.68

38.97

mmol/mol

9.79

8883

83368

Dental caries 1 and operation codes, only avohilmo

11938

56665

1.26

28.17

5.6

5.4

39.31

38.82

mmol/mol

6.26

11132

53207

Nasal polyp

7040

65704

1.37

28.10

6.0

5.8

40.11

40.09

mmol/mol

0.05

6578

60990

Dysplasia of cervi uteri

9269

66900

1.27

28.07

4.3

37.15

37.99

mmol/mol

20.45

8702

62847

Direct fill therapy

4518

41268

1.46

27.92

7.3

5.3

39.58

39.18

mmol/mol

1.57

4301

38623

Childhood asthma (age<16), excluding more controls

4949

35068

1.31

27.90

3.8

3.1

37.00

36.43

mmol/mol

3.37

4708

33540

Malignant neoplasm

39225

239709

0.89

27.78

5.6

39.69

39.60

mmol/mol

1.00

36130

224237

L04AA Selective immunosuppressants

7793

73128

1.35

27.68

8.2

5.3

39.08

39.29

mmol/mol

1.13

7495

68259

Ethmoidectomy

4550

41906

1.51

27.67

5.7

5.4

39.26

39.36

mmol/mol

0.34

4188

39254

Medical abortion

27181

142328

1.16

27.62

5.2

5.0

38.44

38.47

mmol/mol

0.19

25115

132291

Hyperhidrosis

1038

8510

2.35

27.55

6.1

4.7

38.54

38.49

mmol/mol

0.06

963

7977

Undefined dementia

2267

24742

0.73

27.51

7.3

6.8

44.92

42.00

mmol/mol

20.61

1936

21805

Otalgia

2500

22091

1.66

27.43

6.0

5.2

38.95

39.04

mmol/mol

0.18

2314

20549

Childhood asthma (age<16)

4949

35119

1.30

27.43

3.8

3.1

37.00

36.47

mmol/mol

3.04

4708

33593

Benign neoplasm: Stomach

3188

29026

1.71

27.37

7.9

6.1

41.15

40.22

mmol/mol

6.34

2966

26592

Disorders of muscles

3502

31613

1.53

27.34

6.3

5.2

40.03

39.30

mmol/mol

4.66

3307

29337

Calcific tendinitis of shoulder

2078

18454

1.98

27.34

6.6

5.1

40.58

39.26

mmol/mol

8.09

1962

17178

Chronic periodontitis

5191

48018

1.45

27.25

8.3

5.7

41.27

40.08

mmol/mol

10.06

4857

44442

Progressive vascular leukoencephalopathy

958

7815

2.46

27.02

7.3

6.8

42.29

41.47

mmol/mol

1.35

903

6986

Other otitis externa (chronic)

2110

18618

1.84

26.98

7.3

5.5

40.75

39.60

mmol/mol

5.35

1832

17289

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

22383

147282

1.19

26.91

6.5

6.2

40.07

40.35

mmol/mol

3.86

20277

135615

Secondary malignant neoplasm of other and unspecified sites

233

3384

0.34

26.74

4.6

6.5

43.91

40.82

mmol/mol

0.85

193

3109

Parodontitis, under 40 years, or operation codes

3042

26641

1.43

26.65

4.7

3.3

38.49

36.36

mmol/mol

18.36

2900

25447

Superficial injury of abdomen, lower back and pelvis

5121

46894

1.37

26.59

5.9

5.2

39.58

39.15

mmol/mol

2.30

4773

43702

Other/unspecified synovitis and tenosynovitis

4168

38075

1.48

26.54

6.7

5.2

40.76

39.29

mmol/mol

16.80

3890

35251

Specific development disorders of scholastic skills

1232

9774

1.74

26.53

4.8

3.4

37.22

36.73

mmol/mol

0.81

1176

9307

Parodontitis, under 40 years

3036

26593

1.43

26.53

4.7

3.3

38.49

36.37

mmol/mol

18.27

2895

25399

Need for other prophylactic measures

1782

15588

1.97

26.45

7.0

5.6

39.79

39.62

mmol/mol

0.30

1733

14513

Zoster [herpes zoster]

5848

54199

1.38

26.32

7.0

6.0

40.74

40.11

mmol/mol

5.28

5332

49548

FESS (DNB20)

4368

40250

1.51

26.30

5.7

5.3

39.26

39.33

mmol/mol

0.19

4013

37733

Other and unspecified injuries of lower leg

2436

21508

1.64

26.27

5.9

4.9

39.49

38.74

mmol/mol

3.44

2280

20143

Benign neoplasm: Adrenal gland

2375

21487

1.98

26.19

7.9

6.0

42.04

40.12

mmol/mol

17.96

2246

19816

Colonic or urogenital fistula

9981

94435

1.28

26.17

6.3

5.7

39.66

39.71

mmol/mol

0.20

9240

87661

Extracorporeal dialysis

1872

16466

1.94

26.13

17.2

5.9

42.81

40.21

mmol/mol

14.43

1851

15250

Substance abuse, excluding more controls

23307

195867

1.15

26.07

6.4

5.2

40.12

39.38

mmol/mol

18.78

21449

183372

Brain glioblastoma and astrocytoma

313

4334

0.39

26.07

3.8

5.8

39.22

40.08

mmol/mol

0.91

285

4036

Intestinal infectious diseases

41578

313885

1.11

26.04

6.5

5.2

40.77

39.08

mmol/mol

164.26

39017

291652

Hypertrichosis

717

5664

2.84

26.03

6.4

4.0

39.44

37.25

mmol/mol

7.25

687

5368

Ectropion of eyelid

1101

8900

1.92

26.01

7.1

6.8

41.52

41.79

mmol/mol

0.44

984

7965

Prolonged pregnancy

4378

44135

0.76

25.97

2.7

3.7

35.23

36.69

mmol/mol

64.41

4173

42242

Dental caries 2 and operation codes

32841

252514

1.13

25.91

5.2

5.0

38.08

38.86

mmol/mol

47.27

30639

236961

Testicular dysfunction

1175

10006

2.47

25.85

6.4

5.2

40.08

39.84

mmol/mol

0.37

1118

9497

Bell's palsy

4033

36870

1.48

25.79

7.0

5.4

41.72

39.31

mmol/mol

29.81

3746

34106

Wide developmental disorders, excluding more controls

795

5892

1.90

25.75

4.5

3.0

36.51

36.72

mmol/mol

0.22

725

5647

Other disorders of the genitourinary system

4245

39250

1.55

25.75

6.5

6.0

39.82

39.92

mmol/mol

0.32

3877

35892

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

10913

103356

1.25

25.74

5.7

5.5

39.31

39.59

mmol/mol

2.31

10208

96476

Other disorders of gingiva or/and edentulous alveolar ridge

1593

13682

1.88

25.65

8.0

5.4

39.92

39.64

mmol/mol

0.54

1507

12668

Carcinoma in situ of skin of trunk

859

7018

2.70

25.64

7.8

7.0

41.21

41.59

mmol/mol

0.51

772

6355

Acute pancreatitis

6820

63619

1.33

25.62

8.0

5.8

43.69

40.01

mmol/mol

97.65

6369

58680

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

11659

98945

0.80

25.56

5.4

5.7

39.53

39.44

mmol/mol

0.49

10564

91492

Inguinal hernia

25361

164475

1.15

25.56

5.4

5.7

39.15

40.15

mmol/mol

58.79

23502

152832

Benign neoplasm: Caecum

3232

29644

1.71

25.55

7.9

6.6

41.30

40.69

mmol/mol

3.00

3035

27127

Hirsutism in women

630

4907

3.09

25.52

6.4

3.9

39.58

37.14

mmol/mol

7.44

602

4663

Seborrhoeic dermatitis

3184

28807

1.57

25.46

7.1

5.7

40.18

39.89

mmol/mol

0.94

2944

26713

Other endocrine disorders

1549

12471

1.69

25.46

5.8

4.7

37.96

38.46

mmol/mol

1.27

1444

11615

Synovial cyst of popliteal space [Baker]

2477

22166

1.71

25.42

6.5

5.6

40.05

39.87

mmol/mol

0.46

2294

20248

Abnormal findings on diagnostic imaging of other body structures

4309

39849

1.52

25.33

6.7

5.8

40.41

39.72

mmol/mol

4.84

4011

36788

Car occupant injured in other and unspecified transport accidents

6693

62162

1.31

25.31

5.5

4.9

39.38

38.68

mmol/mol

6.78

6237

58344

Early lumbar disc prolapse, operated

3623

32756

1.46

25.28

4.6

4.1

38.65

38.21

mmol/mol

1.79

3463

31466

Atopic dermatitis

23182

189965

1.15

25.28

4.8

4.7

37.83

38.42

mmol/mol

19.28

21745

178841

Artificial joint re-operation

2151

19341

1.98

25.26

7.3

6.4

40.55

40.60

mmol/mol

0.09

2016

17606

Melanocytic naevi

10724

101583

1.25

25.16

5.8

5.4

38.64

39.16

mmol/mol

7.90

10130

94839

Sudden idiopathic hearing loss

3324

30286

1.58

25.08

6.5

5.9

40.07

40.13

mmol/mol

0.14

2988

27939

Orchitis and epididymitis

2929

26080

1.50

25.07

6.7

5.9

40.89

40.55

mmol/mol

0.98

2731

24231

Carcinoma in situ of skin of trunk

859

7042

2.67

25.01

7.8

6.8

41.21

41.32

mmol/mol

0.12

772

6349

Extreme obesity with alveolar hypoventilation

1315

11460

2.51

24.89

10.3

5.4

46.83

39.55

mmol/mol

70.15

1221

10627

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

923

7664

2.64

24.86

9.8

5.4

38.74

39.57

mmol/mol

2.17

900

7182

Dental pulpitis 3

3797

23982

1.31

24.78

3.4

2.7

36.32

35.10

mmol/mol

8.72

3538

22675

Acute tubulo-interstitial nephritis

24673

210677

1.15

24.77

7.2

5.5

41.82

39.24

mmol/mol

217.07

22756

193760

Lichen sclerosus et atrophicus

3360

30876

1.65

24.62

6.8

5.6

40.47

39.54

mmol/mol

7.28

3107

28306

Autoimmune hyperthyroidism

2129

18874

1.75

24.51

5.9

4.7

39.49

38.25

mmol/mol

7.69

1993

17606

Follicular cysts of skin and subcutaneous tissue

6442

60248

1.36

24.49

6.5

5.5

40.46

39.60

mmol/mol

8.67

6063

56088

Dermatophytosis

4269

39325

1.47

24.48

7.2

5.9

41.17

40.08

mmol/mol

9.64

4000

36381

Transient global amnesia

2973

27246

1.74

24.46

5.9

6.4

39.31

40.47

mmol/mol

10.06

2728

24831

Oxycodone

12220

124269

0.83

24.41

7.0

5.9

42.43

40.00

mmol/mol

102.34

11023

113376

Viral and other specified intestinal infections

7384

66542

1.24

24.36

6.1

4.1

41.15

37.66

mmol/mol

93.18

6980

62419

Other diseases of jaws

2347

20867

1.66

24.32

6.3

5.1

39.75

39.23

mmol/mol

1.68

2193

19471

Medicines for HER+ breast cancer

12301

125091

0.81

24.29

5.3

5.8

39.44

39.50

mmol/mol

0.34

11165

115001

Entropion and trichiasis of eyelid

2519

22310

1.56

24.25

6.8

6.6

40.76

41.15

mmol/mol

1.24

2275

20066

Allergic contact dermatitis

4876

45066

1.41

24.15

5.9

5.0

39.33

38.72

mmol/mol

4.73

4513

42174

Dental pulpitis 3, only avohilmo

3480

22194

1.31

24.07

3.2

2.7

36.02

34.98

mmol/mol

6.26

3241

20958

Ménière disease

3182

29059

1.61

24.03

6.2

6.0

39.71

40.11

mmol/mol

1.86

2904

26688

Testicular hypofunction

1044

8878

2.58

23.93

6.5

5.1

40.10

39.79

mmol/mol

0.48

993

8418

Recurrent dislocation of patella

1726

14753

1.64

23.93

4.4

3.7

37.20

37.24

mmol/mol

0.05

1643

13990

Benign neoplasm: Stomach

3188

29245

1.65

23.90

7.9

6.2

41.15

40.27

mmol/mol

5.81

2966

26909

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

11449

69885

1.20

23.79

3.7

3.5

35.89

36.49

mmol/mol

13.75

10897

66864

Malignant neoplasm of heart, mediastinum and pleura, excluding all cancers (controls excluding all cancers)

281

4130

0.43

23.77

4.8

6.6

40.49

41.02

mmol/mol

0.44

246

3769

Diseases of tongue

2102

18684

1.75

23.77

6.5

5.5

39.51

39.74

mmol/mol

0.62

1941

17247

Other symptoms and signs involving general sensations and perceptions

1195

10047

1.99

23.72

6.8

5.6

39.88

39.75

mmol/mol

0.16

1103

9245

Malignant neoplasm of stomach

1055

12824

0.62

23.71

6.7

6.5

41.32

41.06

mmol/mol

0.37

949

11655

Traumatic subdural haemorrhage

4116

36695

1.37

23.70

6.6

5.9

41.48

40.34

mmol/mol

8.42

3697

33082

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

4587

42622

1.47

23.65

6.2

5.6

39.64

39.62

mmol/mol

0.04

4283

39646

Asthma-related pneumonia

12756

120860

1.20

23.61

6.9

5.8

41.58

39.91

mmol/mol

57.28

11963

110534

Asthma-related pneumonia or sepsis

12783

121116

1.20

23.61

6.9

5.8

41.58

39.91

mmol/mol

57.57

11987

110774

Asthma, hospital admissions 3, pneumonia

12783

121116

1.20

23.61

6.9

5.8

41.58

39.91

mmol/mol

57.57

11987

110774

Glomerulonephritis

3248

29469

1.51

23.60

8.9

5.7

40.43

39.89

mmol/mol

2.34

3140

27319

Misadventures to patients during surgical and medical care

4751

44000

1.42

23.60

6.9

5.6

40.33

39.65

mmol/mol

5.08

4438

40696

Non-allergic asthma (mode), excluding more controls

7600

70501

1.28

23.51

6.1

5.3

40.04

39.07

mmol/mol

16.04

7200

64867

Nontraumatic intracranial haemmorrhage

5696

61589

0.79

23.47

6.3

41.11

40.64

mmol/mol

2.86

5231

55772

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

10635

100672

1.23

23.47

5.1

5.0

38.58

38.82

mmol/mol

1.69

10001

94705

Neuralgia and neuritis, unspecified

1714

15057

1.88

23.46

6.3

5.1

39.92

39.19

mmol/mol

2.50

1606

13961

Graves disease, strict definition

3366

30702

1.52

23.44

5.3

4.9

39.07

38.59

mmol/mol

1.90

3125

28792

Arthropathies in other diseases classified elsewhere

1186

10144

2.23

23.41

13.9

5.4

51.42

39.85

mmol/mol

95.02

1125

9344

Anankastic personality disorder

1273

10907

2.08

23.39

5.7

4.6

38.06

38.33

mmol/mol

0.47

1200

10291

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder

903

11113

0.60

23.33

8.6

6.6

43.57

41.11

mmol/mol

8.13

788

10084

Other medical care

13779

141026

0.85

23.27

5.6

5.9

41.31

39.92

mmol/mol

42.95

12495

128848

Perineal laceration during delivery

4656

45524

0.78

23.22

3.2

3.6

35.95

36.40

mmol/mol

4.36

4408

43273

Other disorders of nervous system

2152

19347

1.83

23.20

8.2

5.8

41.86

40.03

mmol/mol

12.16

2002

17851

Other obstetric conditions, not elsewhere classified

11764

71999

1.19

23.19

3.7

3.5

35.94

36.55

mmol/mol

14.78

11194

68897

Pollen allergy

6374

58255

1.27

23.18

4.5

4.1

37.40

37.56

mmol/mol

0.71

5935

55206

Malignant neoplasm of prostate

13823

82949

1.19

23.16

6.6

7.0

40.73

41.54

mmol/mol

17.56

12367

75856

Drug-induced neutropenia

1856

20788

0.63

23.15

5.3

5.8

39.89

39.73

mmol/mol

0.32

1690

19205

Examination and encounter for administrative purposes

1417

12228

1.95

23.15

6.9

5.3

40.84

39.57

mmol/mol

5.15

1329

11165

Other disorders involving the immune mechanism, not elsewhere classified

983

8261

2.40

23.12

9.6

5.4

38.86

39.60

mmol/mol

1.85

958

7730

Other necrotizing vasculopathies (FG)

1920

16982

1.77

23.06

7.6

5.8

40.75

40.23

mmol/mol

1.29

1824

15361

Benign neoplasm: Adrenal gland

2375

21660

1.89

23.01

7.9

6.1

42.04

40.15

mmol/mol

17.41

2246

20062