No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3973 |
4. Check minimum number of eventsNone |
3973 |
5. Include endpointsNone |
3973 |
6. Filter based on genotype QC (FinnGen only) |
3628 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O26
- Name in latin
- Morbositates hepatis in graviditate, intra labores et/sive in puerperio
Similar endpoints
↥List of similar endpoints to
Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
based on the number of shared cases.
Similar with more cases:
- Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8, excluding more controls
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23532 | 23532 | - |
| Only index persons | 23124 | 23124 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.67 | 0.67 | - |
| Only index persons | 0.85 | 0.85 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.44 | - |
| Only index persons | - | 29.44 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3628 | 3628 | - |
| Unadjusted period prevalence (%) | 1.29 | 1.29 | - |
| Median age at first event (years) | 29.74 | 29.74 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3767
- Matched controls
- 37670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
8389.8
307.7
2475
7
A05AA02
ATC
ursodeoxycholic acid; oral
78.6
307.7
1081
192
63900
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Pruritus
+∞
307.7
626
*
6467A
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOSIS GRAVIDARUM]
+∞
307.7
733
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.3
120.3
1374
7546
63998
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Alia definitae
30.2
116.7
77
26
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.0
95.4
480
1764
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.4
90.9
776
3698
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.3
83.9
769
3767
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
82.6
1735
11535
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
81.4
488
1961
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.4
75.1
611
2831
W84
ICPC
Pregnancy high risk
2.9
73.2
382
1424
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.3
72.0
608
2860
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.9
66.9
1164
7155
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.3
65.9
263
839
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
60.9
688
3620
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.9
58.3
1066
6604
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
57.8
702
3788
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.4
52.2
196
601
SPAT1380
SPAT
Postpartum check-up
1.9
51.8
746
4255
SPAT1379
SPAT
Health check-up of pregnant person
1.9
51.1
853
5105
O30.0
ICD-10 Finland
Twin pregnancy
3.7
50.9
165
459
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.6
44.7
1691
12579
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.7
44.4
1062
7018
SPAT1197
SPAT
Extensive health check-up of expecting family
1.8
44.0
933
5961
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.1
43.1
448
2265
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.8
42.0
748
4532
XMA22
NOMESCO Finland
General examination of pregnant woman
2.1
41.6
451
2314
W78
ICPC
Pregnancy
1.7
41.2
1105
7502
MAC96
NOMESCO Finland
Other induction or advancement of labour
2.7
40.1
217
820
O60
ICD-10 Finland
Preterm labour and delivery
2.8
39.9
213
799
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.8
39.0
744
4590
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.4
36.4
262
1135
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
34.7
682
4230
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
4.1
34.6
95
235
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
2.7
33.8
185
702
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.3
33.4
274
1256
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.7
32.8
634
3908
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
1.8
29.7
462
2664
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.6
29.7
733
4812
63901
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Interus gravis
+∞
29.2
28
*
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.7
28.7
619
3920
W29
ICPC
Pregnancy symptom/complaint other
2.3
28.4
220
983
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.0
28.2
324
1689
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.5
27.2
168
678
O99.80
ICD-10 Finland
The fear of childbirth
1.9
27.0
382
2135
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.8
26.8
411
2356
OAA12, ,
SPAT
2.0
26.4
324
1728
63909
ICD-8 Finland
Other toxaemias of pregnancy and the puerperium, Necrosis acuta et subacuta hepatis
+∞
26.1
25
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.6
25.8
707
4746
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.0
25.7
289
1495
L29.9
ICD-10 Finland
Pruritus, unspecified
2.6
24.8
148
587
O82.0
ICD-10 Finland
Delivery by elective caesarean section
1.9
23.8
316
1729
MAA00
NOMESCO Finland
Amniocentesis
2.4
23.8
165
703
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.9
23.4
111
391
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
3.5
23.4
82
241
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.6
23.1
584
3836
OAA11, ,
SPAT
1.7
22.9
414
2488
OAA10, ,
SPAT
1.8
20.8
304
1713
SPAT1196
SPAT
Monitoring of normal pregnancy
1.7
20.4
441
2778
MA3AE
NOMESCO Finland
Combined first trimester screening
1.7
20.4
393
2403
ZXE00
NOMESCO Finland
One hour or less
1.4
19.8
1403
11270
8811
FHL
Cesarean section
1.9
19.8
279
1556
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.7
19.7
107
406
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
1.7
19.4
374
2284
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
1.7
19.1
398
2482
S02
ICPC
Pruritus
2.2
18.9
160
743
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
18.8
1529
12533
ZXD05
NOMESCO Finland
Urgent procedure
1.4
18.0
1094
8531
W90
ICPC
Uncompl labour/delivery livebirth
1.7
18.0
340
2066
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
2.5
17.9
110
444
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
3.7
17.8
55
149
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.2
17.5
142
648
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.8
16.8
81
289
W92
ICPC
Compl labour/ delivery livebirth
2.1
16.1
158
777
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.7
16.1
86
324
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
3.8
15.5
46
121
6663
FHL
Cholecystectomy and cholangiography
3.6
15.3
49
136
W85
ICPC
Gestational diabetes
1.7
15.2
284
1720
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
2.7
15.1
80
300
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
3.1
14.9
61
198
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.3
14.7
115
518
K76.9
ICD-10 Finland
Liver disease, unspecified
3.0
14.3
61
203
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
2.3
14.3
111
498
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.3
14.3
112
505
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
3.7
14.3
45
124
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
3.0
14.2
61
204
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
3.8
14.1
42
111
A02BC01
ATC
omeprazole; systemic
1.4
14.0
855
6626
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.9
14.0
178
961
A10BX01
ATC
guar gum; oral
2.7
14.0
74
278
Z3232
NOMESCO Finland
Midwife
1.5
13.9
522
3713
OAA41, ,
SPAT
1.9
13.8
162
852
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.0
13.6
154
799
6467X
ICD-9 Finland
Other complications of pregnancy, not elsewhere classified, Liver disorders in pregnancy[HEPATOPATHIA ALIA GRAVIDARUM]
+∞
13.5
13
*
Z37.0
ICD-10 Finland
Single live birth
1.4
13.5
573
4170
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
2.3
13.4
103
460
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
3.3
13.4
49
149
O61.0
ICD-10 Finland
Failed medical induction of labour
2.6
13.4
77
302
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
13.2
410
2801
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.2
13.1
50
156
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
13.0
703
5334
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
2.1
12.4
115
555
MAC98
NOMESCO Finland
Other induction of labor
4.6
12.3
29
64
WX320
NOMESCO Finland
Spinalanesthesy
1.4
12.3
745
5755
K83.0
ICD-10 Finland
Cholangitis
3.5
12.2
41
118
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.9
12.1
146
775
O20.0
ICD-10 Finland
Threatened abortion
1.9
12.0
150
805
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.6
11.9
257
1614
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
2.5
11.9
74
302
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
11.7
164
913
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
9.6
11.7
23
24
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
11.6
1547
13301
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
2.0
11.5
120
605
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
11.5
767
6004
O47
ICD-10 Finland
False labour
2.6
11.5
65
253
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
11.4
620
4700
Z36.8
ICD-10 Finland
Other antenatal screening
2.0
11.3
127
659
O61.8
ICD-10 Finland
Other failed induction of labour
3.5
11.1
37
106
SPAT1357
SPAT
Monitoring of problem during pregnancy
1.8
11.0
161
909
W27
ICPC
Fear of complications of pregnancy
2.4
10.9
74
315
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
2.4
10.8
74
316
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
4.7
10.7
24
51
63902, ,
ICD-8 Finland
+∞
10.4
10
*
SPAT1263
SPAT
Sampling
1.3
10.3
1434
12337
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.9
10.3
123
651
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
1.7
10.3
169
987
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.4
10.3
436
3163
B18.2
ICD-10 Finland
Chronic viral hepatitis C
3.0
10.3
44
148
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
3.5
10.2
34
98
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1.8
10.2
143
799
Z2221
NOMESCO Finland
Medical doctor
1.3
10.1
962
7901
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
10.0
1158
9737
Y6099
ICD-8 Finland
Prenatal care and observation
1.8
9.9
149
850
O26.0
ICD-10 Finland
Excessive weight gain in pregnancy
7.6
9.9
22
29
B01AB04
ATC
dalteparin; parenteral
1.8
9.9
150
858
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
3.7
9.9
30
81
OAA70, ,
SPAT
1.9
9.8
122
655
W94
ICPC
Puerperal mastitis
2.6
9.8
55
214
O84.8
ICD-10 Finland
Other multiple delivery
4.4
9.8
24
55
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
2.3
9.8
73
324
57409
ICD-8 Finland
Cholelithiasis, Unspecified
3.4
9.7
34
101
6488A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Abnormal glucose tolerance
2.3
9.5
69
302
WX234
NOMESCO Finland
Paracervical blockade
1.7
9.5
182
1110
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.2
9.3
74
337
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
1.7
9.3
173
1049
J01DB01
ATC
cefalexin; oral
1.3
9.2
3036
28666
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
1.7
9.1
149
870
A10AC01
ATC
insulin (human); parenteral
1.6
9.1
196
1232
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.6
9.1
186
1156
R51.80
ICD-10 Finland
Headache
1.3
8.9
662
5251
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.0
8.8
87
432
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
4.7
8.8
20
43
P01AB01
ATC
metronidazole; oral, rectal
1.2
8.7
1557
13699
G03DA04
ATC
progesterone; systemic, rectal, vaginal
1.7
8.7
160
967
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.2
8.5
70
325
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
1.9
8.3
101
539
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
8.3
1795
16079
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
8.3
1158
9910
L29.8
ICD-10 Finland
Other pruritus
2.4
8.2
53
221
O72.0
ICD-10 Finland
Third-stage haemorrhage
1.7
8.2
135
791
O32.1
ICD-10 Finland
Maternal care for breech presentation
1.5
8.2
239
1612
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.5
8.2
215
1418
W03
ICPC
Antepartum bleeding
2.4
8.2
54
228
K30
ICD-10 Finland
Functional dyspepsia
1.4
8.1
426
3204
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
1.7
8.1
151
917
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.2
8.1
31
98
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
2.2
8.0
62
280
O02.1
ICD-10 Finland
Missed abortion
1.4
7.9
300
2131
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.4
7.9
348
2540
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.1
7.7
74
364
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
2.2
7.7
64
298
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.5
7.5
266
1868
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
2.3
7.5
52
225
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.5
7.4
235
1615
G03DB01
ATC
dydrogesterone; oral
1.3
7.4
642
5188
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
7.3
731
6010
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
1.8
7.2
107
610
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
1.8
7.1
109
628
O40
ICD-10 Finland
Polyhydramnios
2.1
7.1
66
322
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.1
1318
11579
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
1.7
7.1
111
644
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
1.6
7.1
149
935
Z37.2
ICD-10 Finland
Twins, both liveborn
3.4
7.0
24
71
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
2.7
6.9
36
136
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
3.3
6.8
25
77
1413
FHL
Laparoscopy and other therapeutic procedure
1.8
6.8
90
496
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
6.8
1123
9742
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
1.9
6.7
79
419
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.7
276
1992
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
6.7
765
6379
SPAT1391
SPAT
Counselling and guidance related to family situation
2.0
6.7
65
323
WX600
NOMESCO Finland
Single shot through catheter
1.8
6.6
91
508
O98.8
ICD-10 Finland
Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
7.8
6.6
14
18
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
2.2
6.6
50
225
SPAT1373
SPAT
Combined screening in early pregnancy
1.8
6.6
96
545
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.8
6.5
94
532
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.4
6.5
321
2389
L04AX01
ATC
azathioprine; systemic
1.6
6.5
130
805
W99
ICPC
Disorder of pregn/delivery other
2.8
6.5
30
106
G03GB02
ATC
clomifene; oral
1.7
6.5
106
623
6662
FHL
Cholecystectomy
2.6
6.4
34
130
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
1.7
6.4
122
748
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
2.6
6.4
35
136
SPAT1307
SPAT
Psychosocial counselling and guidance
1.4
6.4
269
1952
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
3.7
6.4
19
51
Z22.5
ICD-10 Finland
Carrier of viral hepatitis
11.0
6.3
11
10
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.2
6.3
52
243
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
2.0
6.3
63
317
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.2
2286
21267
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.4
6.1
250
1803
G03AC03
ATC
levonorgestrel; oral, implant
1.3
6.1
492
3931
O85
ICD-10 Finland
Puerperal sepsis
2.1
6.1
54
259
W05
ICPC
Pregnancy vomiting/nausea
2.0
6.1
64
327
TQW30
NOMESCO Finland
Acupuncture
2.5
6.1
36
145
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.1
6.1
55
266
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
2.2
6.1
48
220
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.2
6.0
694
5787
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.4
6.0
324
2447
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
968
957
13.27
307.65
6.3
1.5
10.22
4.57
umol/l
14.55
867
675
358
706
5.50
173.90
1.3
1.3
142.41
153.21
au/ml
0.88
138
177
372
765
5.29
172.38
1.3
1.3
14.08
19.58
u/ml
—
5
17
361
800
4.88
152.87
1.2
1.2
195.03
265.11
u/ml
6.93
285
516
162
252
6.67
99.78
1.2
1.2
83.33
88.23
—
6
13
781
4906
1.75
38.40
1.6
1.6
991.12
1011.33
mu/l
0.24
650
4111
625
3766
1.79
35.18
2.6
2.4
6.22
6.10
umol/l
0.06
550
3196
2030
16309
1.53
34.94
5.7
5.8
9.89
9.67
umol/l
0.34
1931
15498
230
1027
2.32
29.78
1.4
1.2
83.48
172.08
titre
0.84
23
96
1516
11959
1.45
25.51
3.7
3.1
33.50
28.15
u/l
5.50
1442
11400
518
3245
1.69
24.75
1.5
1.5
—
—
—
0
0
390
2308
1.77
22.77
1.8
1.6
—
—
—
0
0
356
2077
1.79
21.79
2.0
1.8
—
—
—
0
0
2738
24435
1.44
21.14
8.5
7.6
80.08
73.49
u/l
11.57
2617
23323
356
2133
1.74
19.83
1.8
1.9
1.45
1.35
g/l
0.33
328
1990
3665
35221
2.50
19.45
13.5
10.5
31.47
23.72
u/l
43.23
3614
34462
431
2733
1.65
19.42
2.7
2.9
10.50
10.39
g/l
0.30
395
2556
411
2595
1.66
18.81
1.5
1.5
—
—
—
0
0
435
2791
1.63
18.67
1.6
1.5
67.12
61.02
ug/l
1.56
347
2334
413
2627
1.64
18.34
1.6
1.5
1.22
1.14
ratio
0.83
253
1590
413
2634
1.64
18.14
1.6
1.5
0.93
0.95
ratio
0.64
254
1597
413
2634
1.64
18.14
1.6
1.5
1.16
1.22
ratio
0.61
256
1606
1257
10099
1.37
17.05
2.6
2.5
62.77
57.48
u/l
0.61
1183
9404
2552
23009
1.34
14.93
4.8
4.2
570.67
1830.94
e6/l
1.25
27
265
288
1772
1.68
14.48
1.6
1.5
61.70
60.08
ug/l
0.25
288
1772
398
2685
1.54
13.64
3.3
4.5
241.22
231.48
u/l
0.20
381
2552
1771
15311
1.30
13.37
10.3
9.8
0.00
0.00
e9/l
0.95
1443
12537
1367
11480
1.30
12.66
6.6
8.0
1.06
1.09
inr
2.78
1136
9391
1068
8769
1.30
11.46
1.5
1.5
2.10
2.13
g/l
0.30
696
5702
974
7912
1.31
11.28
4.2
3.4
98.78
98.19
%
0.36
946
7691
370
2572
1.49
10.95
2.4
2.3
0.22
0.22
g/l
0.07
346
2437
220
1375
1.64
10.44
1.3
1.2
—
—
—
0
0
2926
27366
1.31
10.43
4.1
3.8
—
—
—
0
0
2705
25056
1.28
10.30
3.6
3.0
39.59
34.02
u/l
3.99
2582
24039
92
439
2.12
10.29
1.1
1.1
1.39
1.48
g/l
1.18
81
397
123
659
1.90
9.97
1.7
1.5
—
—
—
0
0
1869
16739
1.23
8.91
2.9
2.6
—
—
estimate
—
0
0
2284
20926
1.23
8.63
3.7
3.3
65.78
71.30
ug/l
1.93
2189
19989
1832
16435
1.22
8.39
6.8
6.2
56.25
56.34
%
0.13
1774
15772
2088
18985
1.22
8.36
3.9
3.6
2.50
3.56
estimate
0.15
520
3933
156
947
1.68
8.34
2.1
1.9
1.15
1.43
g/l
3.38
136
822
1497
13162
1.23
8.33
5.0
4.5
36.75
36.96
g/l
0.81
1412
12448
928
7742
1.26
8.32
1.4
1.3
8.65
8.84
u/ml
0.04
364
3307
1857
16696
1.22
8.28
6.9
6.3
29.76
29.70
%
0.09
1781
15905
1982
17945
1.22
8.21
4.6
4.2
6.17
6.27
mmol/l
1.53
1808
16458
978
8243
1.25
7.97
3.1
2.8
0.19
0.29
e6/l
1.63
684
5845
1206
10415
1.23
7.84
1.4
1.3
1.02
1.62
u/ml
2.71
355
3096
62
284
2.20
7.78
1.1
1.0
310.16
298.38
mg/l
0.37
51
259
236
1611
1.50
7.66
1.9
2.0
0.03
0.01
estimate
0.28
89
589
990
8389
1.24
7.64
1.4
1.4
25.28
26.98
iu/ml
0.17
290
2550
2093
19131
1.21
7.60
4.0
3.7
0.00
0.03
estimate
1.31
512
3834
1249
10875
1.22
7.41
3.3
2.9
0.02
0.14
estimate
0.78
441
3197
418
3179
1.35
7.40
2.6
2.3
35.81
36.96
u/l
0.14
373
2667
55
245
2.26
7.39
1.3
1.2
254.38
196.25
titre
0.21
16
48
1108
9579
1.22
6.96
3.2
3.0
31.52
71.17
e6/l
1.54
795
7103
2052
18816
1.20
6.88
3.9
3.6
0.00
0.00
estimate
1.85
516
3878
1204
10511
1.21
6.83
1.8
1.7
—
—
—
0
0
2692
25349
1.22
6.70
4.9
4.2
10.26
10.06
mm/h
0.39
2573
24121
564
4536
1.29
6.69
2.7
2.6
4.92
4.65
e6/l
0.13
250
2013
1357
12003
1.20
6.68
3.9
3.6
66.72
77.40
e6/l
0.30
882
7818
3392
32843
1.33
6.30
6.2
5.9
1.68
1.74
mu/l
2.24
3250
31463
1987
18264
1.19
6.18
7.1
6.5
0.18
0.18
e9/l
0.03
1798
16345
3103
29729
1.25
6.16
16.4
14.9
13.37
13.37
%
0.00
3073
29356
115
701
1.66
6.15
1.8
1.6
7.64
7.61
mmol/l
0.05
108
674
159
1061
1.52
5.82
2.6
2.4
3.98
3.60
g/l
2.40
146
999
56
278
2.03
5.81
1.4
1.2
1183.33
1007.84
titre
0.48
12
51
87
500
1.76
5.78
1.3
1.2
—
—
—
0
0
947
8199
1.21
5.67
1.9
1.8
1.06
0.89
mg/l
1.26
716
6241
1962
18095
1.18
5.63
7.0
6.3
1.94
1.97
e9/l
0.65
1781
16311
457
3656
1.28
5.63
2.8
2.3
6248.19
6376.75
u/l
0.03
213
1501
618
5131
1.24
5.56
2.2
2.4
14.43
14.27
umol/l
0.22
573
4800
898
7749
1.21
5.55
2.3
2.2
295.81
298.58
umol/l
0.45
808
7038
962
8365
1.20
5.47
2.2
2.0
—
—
—
0
0
1135
10027
1.19
5.40
3.7
3.7
0.01
0.00
estimate
0.29
508
3752
116
735
1.60
5.36
2.0
1.5
9.03
9.32
iu/ml
—
6
15
54
277
1.96
5.15
1.0
1.1
—
—
—
0
0
37
164
2.27
5.13
1.2
1.2
69.49
68.84
ug/l
0.02
37
164
215
1566
1.40
5.03
1.4
1.4
—
—
—
0
0
36
160
2.26
4.97
3.2
3.2
8.55
8.18
mg/l
0.12
29
123
3378
32843
1.28
4.89
12.8
12.3
139.69
139.66
mmol/l
0.39
3324
32177
697
5936
1.21
4.88
3.1
2.5
96.74
99.10
ug/g
0.09
558
4697
96
596
1.63
4.86
2.5
2.7
28.50
28.38
iu/ml
—
5
32
3067
29534
1.21
4.74
5.3
5.0
14.40
14.36
pmol/l
0.42
2901
28044
994
8767
1.18
4.72
2.5
2.2
2.43
2.60
mg/l
2.16
877
7654
122
808
1.53
4.70
4.8
3.4
704.15
367.93
u/ml
0.30
108
696
49
256
1.93
4.48
2.6
2.5
22.76
24.56
mg/l
0.13
34
175
1216
10939
1.16
4.47
3.1
2.7
0.31
0.05
0.81
16
151
56
307
1.84
4.43
1.3
1.2
47.69
61.20
u/l
1.89
51
281
361
2895
1.27
4.38
2.4
2.4
16.55
19.62
au/ml
0.56
35
399
554
4662
1.22
4.36
2.2
2.3
2.47
2.46
g/l
0.08
508
4314
502
4186
1.23
4.32
2.2
2.4
23.64
23.43
%
0.13
467
3881
3377
32918
1.25
4.18
13.0
12.4
3.89
3.90
mmol/l
2.84
3319
32164
469
3905
1.23
4.09
2.4
2.0
28.79
28.95
s
0.25
451
3790
336
2702
1.27
4.00
1.3
1.3
17.66
40.93
au/ml
2.90
11
161
588
5020
1.20
3.98
2.7
2.5
2.15
1.02
e6/l
0.60
271
2502
751
6555
1.18
3.96
2.7
2.5
8.70
8.57
e6/l
0.03
669
5917
239
3046
0.77
3.74
5.1
5.0
—
—
—
0
0
2081
19603
1.14
3.73
9.1
9.3
3.83
3.93
e9/l
1.40
1834
17228
47
262
1.80
3.59
1.3
1.4
—
—
—
0
0
187
1418
1.34
3.49
3.0
2.8
1.02
1.02
ratio
0.83
162
1236
35
179
1.96
3.48
1.8
1.5
2.92
5.92
u/l
1.71
25
151
101
690
1.48
3.45
1.6
1.4
6.51
6.86
mmol/l
0.82
87
625
3444
33743
1.24
3.40
13.9
12.3
17.98
19.14
mg/l
1.47
2828
27199
155
1149
1.36
3.36
2.3
1.6
6.62
12.54
iu/ml
—
6
30
180
1373
1.33
3.25
1.9
2.2
3.00
3.86
iu/l
1.65
78
621
1771
16613
1.12
3.19
2.7
2.5
76.98
75.77
nmol/l
1.14
1655
15635
3266
31866
1.19
3.19
12.0
11.0
90.67
90.23
ml/min/173m2
0.67
3017
29050
3104
30164
1.17
3.17
5.1
4.9
37.00
37.29
mmol/mol
1.44
2966
28812
896
8064
1.15
3.11
1.6
1.6
21.30
20.93
nmol/l
0.34
779
7106
1505
14014
1.12
3.03
1.8
1.8
1.21
1.32
mmol/l
6.78
1297
12250
1408
13069
1.12
2.98
2.0
1.9
102.45
99.57
pmol/l
1.32
736
6950
1547
14442
1.12
2.96
6.0
6.0
1.22
1.22
mmol/l
0.90
1339
12566
316
2621
1.22
2.91
2.5
2.7
—
—
—
0
0
36
202
1.79
2.76
1.3
1.2
—
—
—
0
0
101
724
1.41
2.74
1.2
1.2
—
—
—
0
0
7
14
5.01
2.72
1.0
1.0
—
—
—
0
0
369
3134
1.20
2.68
3.0
3.5
4.57
4.53
pmol/l
0.30
339
2844
53
335
1.59
2.65
1.1
1.2
—
1.16
—
0
11
365
3106
1.19
2.60
1.4
1.3
183.42
180.53
u/ml
0.01
345
2897
228
1851
1.25
2.59
2.3
2.1
7.83
6.88
iu/ml
0.19
54
436
1544
14490
1.11
2.59
3.7
3.4
0.06
0.24
estimate
0.58
429
3211
110
809
1.37
2.59
2.7
2.6
1.79
1.85
index
0.02
58
401
1362
12731
1.11
2.42
5.7
5.5
1.22
1.22
mmol/l
0.81
1292
11871
223
1828
1.23
2.35
1.3
1.3
0.29
1.09
u/ml
2.04
16
141
3565
35197
1.24
2.33
15.4
14.3
66.14
66.46
umol/l
0.50
3544
34828
3208
31409
1.14
2.28
4.2
4.2
5.58
5.62
mmol/l
1.54
3028
29699
928
8533
1.12
2.22
2.0
2.0
133.80
136.65
u/l
0.08
893
8151
218
1797
1.23
2.19
2.0
2.5
65.16
72.62
e9/l
3.15
149
1273
91
672
1.36
2.14
1.5
1.5
—
—
—
0
0
1076
9992
1.11
2.13
2.8
2.8
23.91
37.21
ng/l
0.66
476
4772
10
237
0.42
2.10
7.5
14.1
792.70
6335.79
nmol/l
—
10
227
3717
36934
1.48
2.06
21.5
19.3
266.24
269.33
e9/l
2.50
3673
36420
57
390
1.47
2.06
1.1
1.1
7.48
8.65
iu/ml
0.17
17
116
11
248
0.44
2.05
13.4
19.7
1387.45
5330.87
nmol/l
0.51
11
238
86
636
1.36
2.02
1.8
1.7
16394.58
7469.22
e6/l
0.77
57
456
3717
36939
1.47
2.00
21.4
19.2
90.19
90.43
fl
3.15
3701
36719
98
741
1.33
2.00
2.2
2.3
10.07
10.20
g/l
0.14
93
685
3717
36940
1.47
1.99
21.9
19.5
39.63
40.49
%
2.86
3700
36701
3717
36943
1.46
1.95
21.5
19.3
6.64
6.65
e9/l
0.06
3666
36351
3717
36943
1.46
1.95
21.5
19.2
4.44
4.45
e12/l
0.79
3663
36371
544
4884
1.13
1.95
3.3
3.0
261.17
311.81
ng/l
0.19
296
2712
10
39
2.57
1.94
1.0
1.3
—
—
—
0
0
61
429
1.43
1.93
1.1
1.2
179.98
3108.18
pmol/l
—
9
39
179
1469
1.23
1.92
2.1
2.1
40.05
39.54
u/l
0.13
166
1361
170
1394
1.23
1.84
2.3
2.7
67.71
103.74
ng/l
2.99
150
1243
162
1325
1.23
1.81
1.5
1.6
—
—
—
0
0
3717
36955
1.44
1.81
21.6
19.3
132.19
133.10
g/l
6.22
3700
36732
15
73
2.06
1.80
1.1
1.1
—
—
—
0
0
148
1200
1.24
1.79
1.2
1.2
4.41
4.62
0.11
31
194
506
4552
1.13
1.77
3.2
3.3
0.83
0.82
mmol/l
1.17
482
4317
141
1140
1.25
1.75
1.3
1.3
63.51
38.22
u/ml
—
10
105
219
1853
1.19
1.74
2.2
2.7
66.94
67.39
g/l
0.44
203
1728
12
54
2.23
1.73
1.2
1.1
—
—
—
0
0
110
865
1.28
1.73
1.1
1.1
12.89
15.99
au/ml
0.28
35
240
55
390
1.42
1.70
2.0
1.6
—
—
—
0
0
14
68
2.06
1.70
6.1
5.0
—
—
—
0
0
412
3671
1.14
1.68
2.0
2.2
377.18
376.19
nmol/l
0.04
390
3406
140
1139
1.24
1.66
1.5
1.6
—
—
—
0
0
201
1700
1.19
1.62
1.7
1.7
—
—
—
0
0
89
688
1.30
1.61
2.2
2.1
0.00
0.02
g/l
1.26
83
632
24
143
1.68
1.60
1.1
1.1
—
—
—
0
0
1181
11145
1.09
1.60
1.6
1.6
—
—
—
0
0
27
167
1.62
1.58
1.0
1.1
—
—
—
0
0
449
4043
1.13
1.56
1.3
1.3
172.45
149.25
u/ml
0.53
179
1625
100
790
1.27
1.55
2.7
2.3
0.58
0.63
g/l
0.05
92
701
38
257
1.48
1.52
2.1
1.4
—
—
—
0
0
52
374
1.40
1.52
1.2
1.1
16.47
14.31
u/ml
0.24
27
180
217
1862
1.18
1.50
7.5
7.5
7.58
7.56
mmol/l
0.02
208
1802
155
1292
1.21
1.49
1.3
1.3
6.05
5.23
u/ml
0.08
12
122
875
8177
1.09
1.48
2.2
2.2
—
—
—
0
0
217
2510
0.86
1.44
1.4
1.5
—
—
—
0
0
384
3447
1.13
1.42
4.1
4.1
33.59
32.85
%
0.73
281
2518
43
303
1.42
1.42
1.2
1.2
0.61
0.65
ratio
0.34
18
183
84
659
1.28
1.40
2.1
2.2
0.00
0.00
g/l
-0.00
76
590
457
4149
1.12
1.40
1.8
1.8
—
—
—
0
0
154
1294
1.20
1.38
1.3
1.4
6.28
9.18
u/ml
0.36
16
192
110
895
1.24
1.36
2.1
2.3
7.16
7.31
g/l
0.46
105
844
110
895
1.24
1.36
2.1
2.3
4.24
4.32
g/l
0.55
105
843
81
637
1.28
1.34
3.9
5.2
123.71
426.49
iu/ml
—
7
76
51
376
1.36
1.32
1.4
1.2
—
—
—
0
0
255
2242
1.15
1.32
3.3
3.3
1.23
1.23
mmol/l
1.10
227
1918
844
7920
1.08
1.30
4.4
4.0
8.49
8.53
mg/mmol
0.01
496
4636
166
1414
1.18
1.29
1.3
1.3
84.22
40.24
u/ml
—
6
91
144
1212
1.20
1.28
11.7
9.4
16.08
16.00
%
0.13
137
1163
27
177
1.53
1.28
1.1
1.1
96.27
94.58
%
0.15
11
74
638
5921
1.09
1.27
2.7
2.7
611.28
588.40
ng/l
0.05
517
4866
128
1067
1.21
1.27
2.2
2.0
—
—
—
0
0
109
894
1.23
1.27
2.1
2.3
3.60
3.71
g/l
0.48
104
844
153
1297
1.19
1.26
2.5
2.0
0.23
0.23
g/l
0.24
148
1226
41
294
1.40
1.26
1.5
1.5
277.91
278.78
mosm/kgh2o
0.10
35
240
50
371
1.35
1.25
1.3
1.2
—
—
—
0
0
52
389
1.34
1.24
1.4
1.2
—
—
—
0
0
52
390
1.34
1.22
1.4
1.2
—
—
—
0
0
5
19
2.63
1.21
1.8
1.4
—
—
—
0
0
154
1312
1.18
1.21
1.5
1.6
0.05
0.35
iu/ml
1.11
21
210
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
34
238
1.43
1.20
2.0
2.0
129.86
122.51
%
0.28
34
231
105
864
1.22
1.20
2.1
2.3
2.71
2.86
g/l
0.95
100
814
13
224
0.58
1.17
2.0
2.4
—
—
—
0
0
116
969
1.20
1.15
2.1
1.9
—
—
—
0
0
25
166
1.51
1.14
1.2
1.4
147.36
143.07
mmol/24h
0.11
25
166
786
7398
1.08
1.13
2.1
2.1
—
—
—
0
0
11
58
1.90
1.12
1.0
1.1
—
—
—
0
0
7
31
2.26
1.10
1.1
1.1
—
—
—
0
0
122
1029
1.19
1.10
1.3
1.3
1.21
3.93
u/ml
—
7
61
88
719
1.23
1.09
1.3
1.2
1.24
2.86
u/ml
3.05
33
257
58
451
1.29
1.09
1.4
1.2
—
—
—
0
0
59
460
1.29
1.09
1.7
1.6
—
—
—
0
0
665
6229
1.08
1.08
1.7
1.6
13536812.35
38514566.87
pmol/l
0.95
591
5411
980
9318
1.07
1.06
3.9
3.3
7.39
7.32
mmol/l
0.17
846
8109
6
124
0.48
1.04
4.2
2.7
—
—
—
0
0
28
395
0.71
1.04
5.4
5.9
368.00
376.58
umol/l
0.09
22
344
23
154
1.50
1.03
1.3
1.3
—
1808.57
—
0
7
52
402
1.30
1.03
1.4
1.1
—
—
—
0
0
170
1483
1.15
1.03
1.5
1.6
0.23
0.28
mg/l
0.60
59
604
213
2398
0.88
1.03
1.5
1.5
—
—
—
0
0
7
34
2.06
1.02
1.1
1.1
—
—
—
0
0
25
171
1.47
1.02
1.2
1.2
—
—
—
0
0
25
171
1.47
1.02
1.2
1.1
101.36
97.71
%
0.29
11
72
50
386
1.30
1.01
1.1
1.1
187.38
211.20
mg/l
1.16
44
346
40
299
1.34
1.00
1.2
1.2
—
—
—
0
0
16
250
0.64
1.00
1.4
1.5
0.42
0.50
e9/l
1.42
16
250
5
23
2.18
0.98
1.2
1.0
8.16
8.07
mmol/l
—
5
23
460
4265
1.09
0.97
1.3
1.3
26.47
25.96
iu/l
0.12
405
3691
15
92
1.63
0.97
2.5
2.5
0.63
0.62
mmol/l
0.19
15
92
57
451
1.27
0.96
2.3
2.6
14.22
89.04
ug/min
3.81
39
284
59
469
1.26
0.96
2.0
1.3
531.43
472.63
titre
—
7
38
59
469
1.26
0.96
2.0
1.3
—
106.67
—
0
6
84
695
1.21
0.96
1.4
1.2
2.11
4.33
u/ml
3.19
37
290
23
157
1.47
0.96
1.3
1.6
—
—
—
0
0
40
302
1.33
0.95
1.2
1.2
—
—
—
0
0
62
497
1.25
0.94
1.2
1.2
—
—
—
0
0
62
497
1.25
0.94
1.2
1.2
—
—
—
0
0
80
660
1.22
0.94
1.2
1.1
1.83
2.86
0.56
23
132
8
142
0.56
0.93
2.0
1.4
—
—
—
0
0
21
304
0.69
0.92
1.4
1.5
—
—
—
0
0
2958
29987
0.94
0.91
17.1
15.5
331.36
331.58
g/l
0.77
2940
29831
6
29
2.07
0.89
1.0
1.2
—
—
—
0
0
9
154
0.58
0.88
1.9
1.4
—
—
—
0
0
39
298
1.31
0.87
1.3
1.4
—
—
—
0
0
31
229
1.36
0.86
1.2
1.2
—
—
—
0
0
50
397
1.26
0.85
1.1
1.1
41.61
34.38
mg/l
0.35
40
340
21
145
1.45
0.84
1.2
1.2
—
—
—
0
0
433
4033
1.08
0.84
1.7
1.7
1125.47
1183.55
nmol/l
0.75
351
3145
273
2490
1.10
0.84
1.6
1.7
367.38
303.32
mu/l
0.25
243
2216
31
412
0.75
0.84
1.9
1.5
—
—
—
0
0
51
407
1.26
0.83
1.3
1.3
—
—
—
0
0
22
155
1.42
0.81
1.3
1.6
0.77
2.93
u/field
1.75
13
107
8
47
1.70
0.80
2.1
1.7
—
—
—
0
0
26
352
0.74
0.80
1.6
1.2
60.12
55.84
nmol/l
0.29
26
347
106
916
1.16
0.78
1.4
1.4
315.80
310.86
ug/g
0.09
55
471
15
98
1.53
0.78
2.3
2.1
—
—
—
0
0
0
27
0.00
0.77
0.0
6.2
—
10.54
—
0
27
20
140
1.43
0.76
1.1
1.0
320.60
324.19
ng/l
0.03
15
105
139
1228
1.14
0.76
1.1
1.1
7.40
6.11
eliau/ml
0.07
20
189
45
359
1.26
0.75
1.1
1.1
—
—
—
0
0
20
141
1.42
0.74
1.1
1.0
691.07
810.01
ng/l
0.52
14
102
106
922
1.15
0.73
2.1
2.2
10.36
11.00
mg/l
0.39
99
873
51
415
1.23
0.73
1.3
1.3
—
—
—
0
0
18
254
0.71
0.73
1.4
1.2
9.44
9.28
mm/h
0.03
18
254
15
100
1.50
0.72
1.1
1.1
—
—
—
0
0
131
1478
0.88
0.72
1.3
1.3
12.35
12.09
u/l
0.07
109
1220
32
246
1.30
0.72
2.5
2.8
10.20
14.43
index
3.31
15
149
50
407
1.23
0.71
1.3
1.4
—
—
—
0
0
26
194
1.34
0.71
1.1
1.1
—
—
—
0
0
5
26
1.92
0.70
1.6
1.9
—
—
—
0
0
47
381
1.24
0.70
1.3
1.4
—
—
—
0
0
20
143
1.40
0.70
1.1
1.0
40.67
43.61
ng/l
0.12
15
107
10
61
1.64
0.68
1.1
1.1
1.01
1.25
mom
—
10
61
482
4550
1.07
0.68
1.6
1.7
1.35
1.34
%
0.22
424
4103
18
127
1.42
0.67
1.1
1.1
—
—
—
0
0
47
383
1.23
0.67
1.3
1.4
—
—
—
0
0
45
551
0.81
0.67
1.6
1.4
—
—
—
0
0
85
733
1.16
0.67
1.8
1.9
—
—
—
0
0
10
156
0.64
0.67
1.8
1.4
—
—
—
0
0
33
258
1.28
0.67
1.4
1.1
—
—
—
0
0
80
928
0.86
0.66
1.2
1.2
—
—
—
0
0
59
702
0.84
0.66
1.5
1.6
—
—
—
0
0
39
312
1.25
0.66
1.7
1.7
54.40
51.08
%
0.18
25
179
5
28
1.79
0.66
1.2
2.0
0.60
0.93
u/field
—
5
28
355
3320
1.08
0.66
5.2
5.2
1.04
1.04
mmol/l
0.07
335
3074
16
111
1.44
0.65
1.4
5.7
10792.36
61.36
mg/l
0.47
11
76
12
78
1.54
0.65
1.4
1.3
10.42
13.51
u/l
0.50
12
71
47
385
1.22
0.65
1.3
1.4
—
—
—
0
0
11
70
1.57
0.65
1.1
1.1
—
—
—
0
0
99
867
1.15
0.65
1.1
1.1
1.69
4.35
u/ml
2.22
45
361
5
29
1.73
0.64
2.2
2.4
—
—
—
0
0
26
199
1.31
0.62
1.3
1.5
71.19
67.92
umol/l
0.44
26
199
39
315
1.24
0.62
1.9
1.9
18.45
24.32
mg/l
0.39
13
121
158
1431
1.11
0.61
3.4
3.1
5.09
5.15
kpa
0.43
149
1385
138
1241
1.12
0.61
1.2
1.1
1.80
2.16
u/ml
0.20
77
627
155
1403
1.11
0.61
1.6
1.5
—
—
—
0
0
90
788
1.15
0.60
1.5
1.6
352.68
375.38
mu/l
0.24
71
623
0
20
0.00
0.60
0.0
1.0
—
0.29
—
0
6
0
22
0.00
0.59
0.0
1.0
—
0.18
—
0
7
85
743
1.15
0.59
1.4
1.6
—
—
—
0
0
26
201
1.30
0.58
1.6
1.9
0.64
2.00
u/field
1.66
11
110
114
1276
0.89
0.58
5.8
6.9
24.72
24.35
mmol/l
0.60
105
1216
186
1704
1.10
0.58
1.6
1.7
9.85
11.16
u/ml
0.21
49
465
36
442
0.81
0.58
1.5
1.6
—
—
—
0
0
56
474
1.18
0.58
1.3
1.4
—
3133.33
—
0
6
6
35
1.72
0.57
2.2
2.4
31.50
21.01
mg/l
—
6
35
12
81
1.48
0.57
1.1
1.1
—
—
—
0
0
99
878
1.13
0.56
1.1
1.2
3.64
3.59
mmol/l
0.21
94
835
78
681
1.15
0.55
1.2
1.3
—
—
—
0
0
6
37
1.62
0.55
1.3
1.2
—
—
—
0
0
16
116
1.38
0.54
1.0
1.1
—
—
—
0
0
9
61
1.48
0.53
1.2
1.5
1.21
1.19
mmol/l
—
9
61
27
338
0.80
0.52
1.1
1.1
—
—
—
0
0
19
143
1.33
0.52
1.5
1.6
—
—
—
0
0
19
143
1.33
0.52
1.5
1.6
—
—
—
0
0
19
143
1.33
0.52
1.5
1.6
—
—
—
0
0
19
143
1.33
0.52
1.5
1.6
—
—
—
0
0
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
10
145
0.69
0.50
3.5
2.2
1.77
1.03
ug/l
—
10
138
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
66
755
0.87
0.50
1.5
1.6
—
—
—
0
0
10
67
1.49
0.49
1.1
1.4
—
—
—
0
0
7
45
1.56
0.49
1.1
1.2
—
—
—
0
0
216
2014
1.08
0.48
1.6
1.7
—
—
—
0
0
240
2249
1.07
0.47
1.4
1.4
226.06
241.37
miu/ml
0.27
118
1161
91
815
1.12
0.47
1.1
1.1
—
0.43
—
0
6
3344
33238
1.05
0.47
4.8
4.8
2.83
2.87
mmol/l
2.73
3203
31791
3311
32905
1.05
0.46
4.4
4.3
1.56
1.56
mmol/l
0.08
3177
31468
38
319
1.19
0.45
1.2
1.5
—
—
—
0
0
192
1787
1.08
0.45
1.1
1.1
0.58
0.60
ratio
0.33
29
193
29
237
1.23
0.45
1.9
1.6
46.66
41.34
%
0.29
20
129
130
1418
0.91
0.45
15.0
8.9
94.60
94.43
%
0.09
130
1413
3322
33020
1.05
0.45
4.5
4.4
4.77
4.85
mmol/l
5.32
3196
31700
26
319
0.81
0.44
1.6
1.5
—
—
—
0
0
268
2527
1.07
0.44
1.6
1.5
—
—
—
0
0
13
95
1.37
0.43
1.2
1.2
—
—
—
0
0
13
95
1.37
0.43
1.2
1.2
—
—
—
0
0
271
2559
1.06
0.43
1.1
1.1
—
—
—
0
0
102
925
1.11
0.43
3.6
5.1
1.76
1.64
%
0.32
95
873
114
1040
1.10
0.43
1.1
1.1
0.93
1.52
u/ml
0.67
55
501
14
104
1.35
0.43
1.1
1.1
97.79
98.73
%
0.05
14
104
9
131
0.69
0.43
3.3
2.5
153.78
165.23
nmol/l
—
9
117
126
1371
0.92
0.42
1.4
1.3
3.19
3.64
ug/l
0.54
117
1261
307
2916
1.06
0.41
1.5
1.7
—
—
—
0
0
36
305
1.18
0.40
1.1
1.1
1.08
1.04
ratio
0.87
31
247
96
872
1.10
0.40
1.2
1.4
895.80
5499.95
e6/l
0.52
69
674
38
444
0.85
0.40
1.3
1.6
—
—
—
0
0
5
34
1.47
0.40
1.4
1.1
—
—
—
0
0
195
1829
1.07
0.39
1.9
1.7
3.05
4.13
mg/l
1.62
152
1335
5
35
1.43
0.39
1.6
1.7
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
51.20
87.77
titre
—
5
35
74
664
1.12
0.39
1.5
1.3
—
—
—
0
0
1124
10995
1.03
0.38
3.1
3.2
2.35
2.35
mmol/l
0.16
1032
10221
11
80
1.38
0.38
2.2
3.1
0.86
1.38
%
0.69
11
80
230
2175
1.06
0.37
3.4
3.3
71.82
74.44
ng/l
0.23
207
1924
21
257
0.82
0.37
1.6
2.3
617.19
500.28
e6/l
0.91
16
198
19
152
1.25
0.37
1.3
1.4
12.45
13.86
pmol/l
0.77
19
125
123
1138
1.08
0.36
1.4
1.4
25.59
25.46
u/l
0.01
98
945
5
77
0.65
0.35
2.2
6.4
4.75
4.76
kpa
—
5
77
5
77
0.65
0.35
2.2
6.4
11.12
11.13
kpa
—
5
77
108
995
1.09
0.35
1.2
1.3
439.24
457.19
mg/l
0.19
102
958
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
234
2467
0.95
0.35
2.3
2.4
76.02
75.59
ml/min/173m2
0.07
95
1026
101
928
1.09
0.35
1.1
1.1
0.82
4.56
u/ml
4.29
48
438
23
277
0.83
0.35
4.5
6.0
6.84
6.97
mmol/l
0.06
16
233
609
5907
1.04
0.35
1.8
2.0
—
—
—
0
0
132
1415
0.93
0.33
14.8
8.9
1.11
1.30
%
1.91
132
1407
42
368
1.14
0.33
1.2
1.2
0.46
1.03
u/ml
0.92
21
178
15
188
0.80
0.33
1.3
1.6
—
—
—
0
0
106
982
1.08
0.32
1.2
1.3
—
—
—
0
0
16
128
1.25
0.31
1.1
5.0
—
379.50
—
0
14
36
412
0.87
0.31
1.5
1.4
—
—
—
0
0
24
284
0.84
0.31
1.5
2.2
—
—
—
0
0
33
286
1.16
0.31
1.1
1.1
1.00
1.06
u/l
0.71
11
107
128
1367
0.93
0.30
15.0
9.1
0.66
0.65
%
0.03
128
1360
53
589
0.90
0.30
1.1
1.2
2.13
19419.63
iu/ml
—
8
138
128
1199
1.07
0.30
3.4
2.9
1.80
1.66
mmol/l
0.18
82
893
115
1073
1.07
0.30
1.1
1.1
3.35
5.14
u/ml
0.82
55
568
15
185
0.81
0.29
2.7
1.6
—
—
—
0
0
67
613
1.09
0.28
2.8
2.6
—
—
—
0
0
9
116
0.78
0.27
1.9
2.3
15.30
15.90
umol/l
—
9
116
12
95
1.26
0.26
1.0
1.3
—
—
—
0
0
75
694
1.08
0.25
1.1
1.1
—
—
—
0
0
55
602
0.91
0.25
1.4
1.4
—
—
—
0
0
14
114
1.23
0.25
1.6
1.3
508.49
428.27
u/l
0.16
14
108
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
58
531
1.09
0.25
3.4
3.9
0.39
0.36
iu/ml
0.31
27
282
46
416
1.11
0.24
1.1
1.2
—
—
—
0
0
92
860
1.07
0.24
1.2
1.3
5.03
27.01
e6/l
2.12
60
626
38
340
1.12
0.24
2.3
2.6
—
—
—
0
0
231
2219
1.04
0.24
2.5
2.3
0.26
0.32
e6/l
0.35
218
2076
6
82
0.73
0.24
1.2
1.2
—
—
—
0
0
15
124
1.21
0.24
1.1
1.2
—
—
—
0
0
65
703
0.92
0.23
1.4
1.4
—
—
—
0
0
55
504
1.09
0.23
1.2
1.1
—
—
—
0
0
24
275
0.87
0.23
1.5
1.6
—
—
—
0
0
5
38
1.32
0.23
2.0
1.7
5.80
5.79
ug/l
—
5
38
258
2489
1.04
0.23
4.7
4.0
56.52
33.00
ug/l
0.25
191
1847
11
88
1.25
0.22
1.0
1.1
—
—
—
0
0
203
2113
0.96
0.22
3.7
3.4
1.74
1.78
mmol/l
0.05
173
1871
14
116
1.21
0.22
1.1
1.1
—
—
—
0
0
3120
31070
1.02
0.21
3.8
3.7
1.11
1.20
mmol/l
14.90
2991
29552
83
778
1.07
0.21
1.1
1.1
0.05
0.28
u/ml
0.87
25
219
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
4.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
38.50
—
0
13
0
13
0.00
0.21
0.0
1.4
—
26.88
—
0
13
108
1023
1.06
0.21
1.1
1.1
0.98
0.95
u/ml
0.02
45
424
20
173
1.16
0.20
1.3
1.5
120.80
129.12
nmol/l
0.48
20
173
141
1476
0.95
0.20
2.1
2.0
11.21
5.40
ug/l
1.03
123
1313
136
1299
1.05
0.20
1.3
1.5
0.36
0.50
nmol/l
2.24
111
1047
15
127
1.18
0.19
1.1
1.1
15.47
34.98
iu/ml
1.68
15
127
46
423
1.09
0.19
4.4
8.0
105.20
105.44
mmol/l
0.11
40
380
299
2905
1.03
0.19
3.2
3.0
34.11
43.96
u/ml
0.53
289
2815
94
993
0.95
0.19
1.2
1.1
—
—
—
0
0
28
312
0.90
0.19
1.4
1.6
—
—
—
0
0
94
992
0.95
0.19
1.2
1.1
—
—
—
0
0
237
2445
0.97
0.18
10.1
7.5
0.52
0.83
mmol/l
0.61
195
1990
15
128
1.17
0.18
1.1
1.2
—
—
—
0
0
63
590
1.07
0.18
3.3
3.6
28.00
21.55
mg/l
0.66
43
403
198
2048
0.96
0.18
11.3
8.3
119.08
120.52
g/l
0.52
190
2002
19
216
0.88
0.17
1.2
1.3
—
—
—
0
0
65
610
1.07
0.17
1.8
2.2
130.08
130.07
g/l
0.00
53
496
11
91
1.21
0.17
1.1
1.1
—
—
—
0
0
31
281
1.10
0.17
1.8
1.9
—
—
—
0
0
82
777
1.06
0.17
2.6
2.1
168.28
322.95
ug/l
0.76
70
699
10
120
0.83
0.16
1.0
1.0
—
—
—
0
0
8
68
1.18
0.16
1.8
1.7
13.59
63.06
u/l
—
8
62
27
298
0.91
0.16
1.1
1.1
1651.78
1532.13
miu/ml
0.28
27
298
30
328
0.91
0.15
1.3
1.3
—
53.33
—
0
15
211
2170
0.97
0.15
3.7
3.4
5.73
5.80
kpa
0.48
206
2109
288
2813
1.03
0.14
1.6
1.7
—
—
—
0
0
12
139
0.86
0.14
2.3
1.4
4733.00
75616.45
e6/l
—
5
74
25
228
1.10
0.13
1.2
1.3
—
—
u/ml
—
0
0
13
113
1.15
0.13
1.2
1.1
—
—
—
0
0
47
443
1.06
0.12
1.2
1.2
0.18
0.21
nmol/l
0.23
36
321
56
531
1.06
0.12
3.6
3.6
2.23
2.76
ratio
0.19
30
299
844
8353
1.01
0.12
3.7
3.7
1.02
1.39
kg/l
0.80
579
5435
17
189
0.90
0.12
1.1
1.0
15.43
11.79
u/ml
—
10
139
29
269
1.08
0.11
1.6
1.7
0.46
1.67
u/ml
—
5
74
581
5741
1.01
0.11
2.5
2.5
2.43
2.43
mmol/l
0.07
512
5148
24
260
0.92
0.11
5.3
7.5
107.68
93.27
ug/l
0.04
14
167
427
4210
1.02
0.10
1.6
1.6
3.41
3.46
mmol/l
0.46
297
2781
42
442
0.95
0.09
1.1
1.1
—
—
—
0
0
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.2
1.1
—
—
—
0
0
243
2467
0.98
0.07
10.0
7.4
13.69
13.58
kpa
0.10
233
2376
6
72
0.83
0.07
1.3
1.5
—
1.08
—
0
6
243
2466
0.98
0.07
10.0
7.4
5.08
5.06
kpa
0.13
233
2379
8
78
1.03
0.07
1.1
1.1
—
—
—
0
0
9
84
1.07
0.07
1.2
1.3
—
—
—
0
0
63
610
1.03
0.07
3.6
3.9
33.78
44.11
mg/l
0.68
55
531
22
234
0.94
0.06
1.4
1.5
—
—
—
0
0
22
234
0.94
0.06
1.4
1.5
—
—
—
0
0
22
234
0.94
0.06
1.4
1.5
—
—
—
0
0
209
2120
0.99
0.06
10.8
8.0
96.16
96.36
%
0.17
200
2052
57
552
1.03
0.06
2.2
2.7
0.89
0.87
nmol/l
0.10
47
476
15
162
0.93
0.06
2.2
1.3
1418.60
3505.74
e6/l
—
10
109
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
182
0.93
0.05
1.2
1.1
—
—
—
0
0
56
577
0.97
0.05
1.4
1.4
55.42
35.58
nmol/l
0.46
48
523
73
714
1.02
0.04
1.1
1.1
1.66
3.56
eliau/ml
2.43
38
371
70
685
1.02
0.04
2.2
2.0
5.08
5.30
mmol/24h
0.29
65
627
21
220
0.95
0.03
1.1
1.1
—
—
—
0
0
18
189
0.95
0.03
1.4
1.6
117.22
89.87
ng/l
0.29
18
189
11
102
1.08
0.03
1.2
2.0
43.33
41.05
g/l
2.18
11
102
77
758
1.02
0.03
2.5
1.9
1.43
2.10
ug/l
0.42
67
684
21
219
0.96
0.03
2.1
1.4
4818.21
83692.61
e6/l
1.28
14
147
46
470
0.98
0.02
3.5
4.9
34.31
93.93
u/ml
—
10
160
75
739
1.02
0.02
4.2
2.8
25.04
24.85
mmol/l
0.25
66
685
482
4802
1.00
0.02
1.6
1.9
—
—
—
0
0
548
5462
1.00
0.02
1.8
1.8
3.18
3.27
ratio
1.27
419
3983
10
93
1.08
0.02
1.0
1.0
—
—
—
0
0
10
93
1.08
0.02
1.0
1.1
—
—
—
0
0
11
103
1.07
0.02
1.7
1.8
—
—
—
0
0
62
611
1.01
0.02
3.6
3.9
27.20
38.00
mg/l
0.91
55
530
10
94
1.06
0.01
1.1
1.0
64.74
76.39
ug/l
—
10
79
11
104
1.06
0.01
1.7
1.8
—
—
—
0
0
11
104
1.06
0.01
1.7
1.8
—
—
—
0
0
16
154
1.04
0.00
1.1
1.1
—
0.12
—
0
5
22
214
1.03
0.00
1.3
1.7
1.52
4.06
nmol/l
1.22
15
162
61
616
0.99
0.00
1.5
1.3
1.24
1.53
nmol/l
0.87
49
532
10
102
0.98
0.00
1.1
1.1
—
—
—
0
0
17
168
1.01
0.00
1.5
1.3
5.76
6.21
mmol/l
0.57
17
155
19
188
1.01
0.00
3.4
4.0
—
—
—
0
0
34
345
0.99
0.00
1.1
1.1
105.50
116.08
pmol/l
0.72
34
345
180
1798
1.00
0.00
3.0
2.9
4.76
4.59
kpa
0.43
174
1745
234
2338
1.00
0.00
1.4
1.4
—
—
—
0
0
10
99
1.01
0.00
1.1
1.1
—
—
—
0
0
17
169
1.01
0.00
2.1
1.4
36.94
34.92
g/l
0.26
17
155
10
104
0.96
0.00
1.0
1.4
—
—
—
0
0
10
104
0.96
0.00
1.0
1.4
—
—
—
0
0
17
174
0.98
0.00
1.5
1.5
—
—
—
0
0
25
246
1.02
0.00
1.3
1.6
0.82
1.14
promille
0.59
19
196
10
103
0.97
0.00
1.4
1.6
8.50
8.38
ug/l
—
10
103
18
177
1.02
0.00
1.1
1.4
72.90
240.72
nmol/24h
0.55
18
177
0
9
0.00
0.00
0.0
4.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.77
—
0
6
8
85
0.94
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
49.46
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
19.20
—
0
5
9
90
1.00
-0.00
1.1
1.1
—
—
—
0
0
10
100
1.00
-0.00
1.1
1.1
4.08
6.33
u/ml
—
10
100
0
8
0.00
-0.00
0.0
1.0
—
4.38
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
73
0.96
-0.00
1.1
1.3
5.59
5.54
mmol/l
—
7
73
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint O15_ICP_WIDE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_ICP_WIDE | 0.645 [0.51, 0.82] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 13316 females with O15_ICP_WIDE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_ICP_WIDE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.347% | No data |
| 10 | 0.859% | No data |
| 15 | 1.645% | No data |
| 20 | 2.956% | No data |
Relationships between endpoints
↥Index endpoint: O15_ICP_WIDE – Intrahepatic Cholestasis of Pregnancy (ICP) , incl. ICD-8
GWS hits: 33
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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