Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3011412	b-cd3	e6/l (—)	1244	3842	100.00%	Distribution not available
3011412	b-cd3	e9/l (e9/l)	1220	2432	0.70%
3011412	b-t-cd3	e9/l (e9/l)	758	1749	0.00%
3011412	b-t-cd3	— (—)	593	952	100.00%	Distribution not available
3011412	b-t-cd3	e6/l (e9/l)	577	1128	0.00%
3011412	b-cd3	— (—)	149	177	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Transplanted organ and tissue status

339

314

11.74

320.01

5.5

2.4

0.99

1.19

e9/l

1.83

168

192

General symptoms and signs

1310

1810

3.67

317.35

2.7

2.2

1.19

1.16

e9/l

0.34

805

1054

Abnormal findings on diagnostic imaging of lung

684

1335

5.11

316.83

2.3

1.04

1.12

e9/l

1.04

348

852

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

192

41.42

313.45

2.8

2.2

1.19

1.04

e9/l

0.50

140

Follicular lymphoma, hilmo

220

27.00

311.50

2.9

2.0

1.06

1.04

e9/l

0.08

159

Anaemias

490

386

8.70

310.80

3.1

2.4

1.10

1.36

e9/l

3.53

307

203

Second line medication for Crohn's disease

970

2043

4.87

307.65

2.3

2.5

1.09

1.19

e9/l

1.90

568

1257

Primary_lymphoid and hematopoietic malignant neoplasms

1224

436

31.69

307.65

3.1

2.1

1.14

1.13

e9/l

0.10

810

248

Other septicaemia

572

913

6.32

307.65

3.1

2.2

1.13

1.19

e9/l

0.53

350

556

Oral corticosteroids

1717

1954

5.43

307.65

2.2

2.6

1.14

1.18

e9/l

0.55

1053

1149

Other bacterial diseases

1419

2208

4.53

307.65

2.8

2.3

1.10

1.19

e9/l

1.77

874

1312

Non-follicular lymphoma

594

210

33.67

307.65

2.7

1.9

1.08

1.02

e9/l

0.49

411

113

Autoimmune diseases excluding thyroid diseases, strict definition

1413

2072

3.86

307.65

2.6

2.4

1.12

1.22

e9/l

2.35

801

1289

1340

1665

5.14

307.65

2.4

2.3

1.14

1.18

e9/l

0.40

832

982

Secondary uncertain malignant neoplasm

473

312

16.60

307.65

2.7

2.1

1.03

1.08

e9/l

0.31

310

176

Autoimmune diseases related-to ILD

1219

2633

4.15

307.65

2.7

2.3

1.16

1.18

e9/l

0.27

673

1605

Pneumonias (Asthma/COPD co-morbidities)

1448

2481

4.12

307.65

2.5

2.4

1.15

1.20

e9/l

1.01

904

1458

ILD medications: immunosuppressive drugs

1342

1420

9.39

307.65

2.7

2.3

1.08

1.24

e9/l

4.02

783

885

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

1340

1665

5.14

307.65

2.4

2.3

1.14

1.18

e9/l

0.40

832

982

Enlarged lymph nodes

555

385

15.49

307.65

2.8

2.3

1.08

1.25

e9/l

2.12

382

228

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

476

273

18.84

307.65

2.6

2.2

1.03

1.05

e9/l

0.09

313

159

Septicaemia

637

1044

6.03

307.65

3.0

2.2

1.14

1.18

e9/l

0.29

393

638

Influenza and pneumonia

1497

2523

3.97

307.65

2.5

2.4

1.16

1.21

e9/l

0.94

933

1473

Pneumonia, organism unspecified

1275

2257

4.16

307.65

2.5

1.16

1.20

e9/l

0.53

777

1327

Malignant neoplasm

1138

1689

4.06

307.65

2.9

2.2

1.10

1.22

e9/l

2.98

744

932

Diffuse large B-cell lymphoma

289

36.46

307.65

2.4

1.8

1.00

1.08

e9/l

0.39

206

Bacterial infection, other or unspecified

966

1288

6.98

307.65

2.9

2.2

1.06

1.19

e9/l

2.66

603

783

All pneumoniae

1441

2539

3.99

307.65

2.5

1.14

1.21

e9/l

1.39

906

1488

Non-Hodgkin lymphoma, all

224

36.17

307.65

3.0

1.9

1.18

1.03

e9/l

0.56

150

Secondary and unspecified malignant neoplasm of lymph nodes

439

217

23.29

307.65

2.7

2.2

1.05

1.08

e9/l

0.16

287

121

Inflammatory bowel disease treatment related agents

1762

2104

4.85

307.65

2.3

2.6

1.16

1.20

e9/l

0.68

1077

1251

ILD medications

1957

1681

6.53

307.65

2.6

2.3

1.15

1.24

e9/l

1.76

1145

1043

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

903

1898

4.51

307.65

2.4

1.09

1.14

e9/l

0.58

476

1195

Primary_lymphoid and hematopoietic malignant neoplasms

1224

541

25.53

307.65

3.1

2.1

1.14

1.08

e9/l

0.70

810

327

ILD medications: prednisolone, methylprednisolone, prednisone

1779

1611

6.37

307.65

2.4

2.3

1.15

1.24

e9/l

1.64

1061

994

Certain disorders involving the immune mechanism

677

628

11.65

307.65

2.9

2.4

1.27

1.15

e9/l

1.41

482

373

Immunodeficiencies

420

138

39.23

307.65

2.8

2.4

1.35

1.29

e9/l

0.23

315

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

829

234

41.68

307.65

2.8

1.9

1.13

1.02

e9/l

0.88

583

133

Demyelinating diseases of the central nervous system

437

252

19.56

307.65

3.8

2.1

1.24

1.27

e9/l

0.15

209

155

MS-disease / Multiple Sclerosis

409

196

23.92

307.65

3.8

2.0

1.25

1.27

e9/l

0.09

193

125

Immunodeficiency with predominantly antibody defects

331

77.24

307.65

2.7

2.0

1.33

1.24

e9/l

0.25

239

Other and unspecified immunodeficiencies with predominantly antibody defects

179

96.51

307.65

2.9

1.4

1.36

1.63

e9/l

0.48

138

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

1373

2565

3.83

307.65

2.4

2.5

1.15

1.20

e9/l

0.73

856

1508

Other diseases of blood and blood-forming organs, wide

659

691

10.18

307.65

3.1

2.4

1.12

e9/l

0.00

450

407

Diffuse large B-cell lymphoma, helper endpoint

289

54.52

307.65

2.4

2.0

1.00

1.17

e9/l

0.62

206

L04AA Selective immunosuppressants

551

774

7.49

307.65

2.8

2.5

1.05

1.21

e9/l

2.28

321

466

Agranulocytosis

407

328

13.58

307.65

3.2

2.2

1.04

1.14

e9/l

0.87

297

199

L04AX Other immunosuppressants

945

1982

4.90

307.65

2.3

2.5

1.09

1.19

e9/l

1.82

560

1210

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

1830

2131

6.32

307.65

2.6

2.3

1.15

1.20

e9/l

0.92

1174

1216

Fever of other and unknown origin

1119

1396

7.67

307.65

2.9

2.2

1.19

1.16

e9/l

0.27

695

820

First line medication for Crohn's disease

1761

1688

5.80

307.65

2.6

2.4

1.14

1.26

e9/l

3.05

1061

1011

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

289

54.52

307.65

2.4

2.0

1.00

1.17

e9/l

0.62

206

Non-follicular lymphoma, hilmo, excluding all cancers

594

158

44.82

307.65

2.7

1.8

1.08

1.01

e9/l

0.45

411

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

658

739

8.06

307.65

2.4

2.1

0.99

1.09

e9/l

1.27

451

397

Follicular lymphoma

220

40.81

307.65

2.9

2.0

1.06

1.10

e9/l

0.13

159

Autoimmune diseases excluding thyroid diseases

1456

2131

3.85

307.65

2.6

2.4

1.13

1.22

e9/l

2.20

831

1322

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

193

38.77

306.32

4.3

2.8

1.40

1.30

e9/l

0.20

124

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

1095

1704

3.86

301.85

3.0

2.3

1.10

1.23

e9/l

2.92

709

951

Malignant neoplasm, wide definition for exclusion

1093

1703

3.85

300.79

3.0

2.3

1.10

1.23

e9/l

2.87

708

950

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

1093

1703

3.85

300.77

3.0

2.3

1.10

1.23

e9/l

2.87

708

950

Explicit Sepsis

658

1288

5.02

296.86

3.0

2.3

1.14

1.20

e9/l

0.69

405

789

Aplastic and other anaemias

639

1240

5.00

286.34

2.7

2.3

0.96

1.16

e9/l

4.89

413

751

Lymphoid leukaemia

208

24.01

285.06

3.8

2.3

1.39

1.24

e9/l

0.48

125

Kela reimbursement Agammaglobulinemia (D80-84)

145

126.63

278.79

3.4

1.4

1.19

1.21

e9/l

—

113

GASTRO-related operations

933

1095

4.33

277.17

2.8

2.2

1.18

1.28

e9/l

1.72

561

668

Any gastric operation

933

1095

4.33

277.17

2.8

2.2

1.18

1.28

e9/l

1.72

561

668

Nonhereditary hypogammaglobulinemia

147

100.10

276.55

2.6

1.6

1.21

1.10

e9/l

—

107

ILD medications: azathioprine

313

320

10.19

273.70

2.5

2.3

1.09

1.21

e9/l

0.84

176

213

Certain infectious and parasitic diseases

1115

1530

3.69

272.30

2.6

2.2

1.23

1.18

e9/l

0.59

689

899

Rare circulating lymphoid malignancy

193

26.37

268.38

4.3

2.4

1.40

1.21

e9/l

0.53

124

COPD/asthma related infections

1164

1667

3.54

268.27

2.4

2.3

1.21

1.18

e9/l

0.30

701

984

COPD/asthma/ILD related infections

1164

1667

3.54

268.27

2.4

2.3

1.21

1.18

e9/l

0.30

701

984

Other demyelinating diseases of the central nervous system

194

24.99

267.67

3.8

2.2

1.23

1.31

e9/l

0.31

Other and unspecified anaemias

581

1159

4.97

259.89

2.7

2.2

0.94

1.17

e9/l

5.53

377

705

Other anaemias

584

1169

4.94

259.12

2.7

2.2

0.94

1.17

e9/l

5.84

378

711

Other and unspecified types of non-Hodgkin lymphoma, hilmo

192

22.56

254.27

2.8

2.0

1.19

1.03

e9/l

0.76

140

Dental caries

472

826

5.84

253.42

3.3

2.3

1.11

1.19

e9/l

0.84

306

495

Any reimbursement code in KELA

681

644

5.37

252.99

2.7

2.2

1.23

1.45

e9/l

3.66

413

350

Other degenerative diseases of the nervous system

472

571

6.45

251.43

3.7

2.1

1.21

1.10

e9/l

1.31

231

368

Bacterial pneumonia (organism specified)

629

1284

4.56

249.22

2.3

2.5

1.15

1.17

e9/l

0.18

449

759

Drug-induced neutropenia

238

191

13.60

246.59

3.1

1.9

0.99

1.06

e9/l

0.44

198

110

Purpura and other haemorrhagic conditions

334

428

8.24

245.41

3.1

2.6

1.02

1.15

e9/l

1.24

234

255

Autoimmune diseases

1280

2149

3.08

241.73

2.6

2.4

1.15

1.23

e9/l

1.54

727

1333

Any event in cancer register

1073

1942

3.32

240.44

2.9

2.3

1.10

1.24

e9/l

3.65

701

1082

Viral infections characterized by skin and mucous membrane lesions

637

1569

4.15

229.89

2.7

2.6

1.22

1.19

e9/l

0.25

408

934

Bacterial Sepsis

581

1164

4.53

227.12

2.6

2.3

1.13

1.15

e9/l

0.11

371

711

Thrombocytopenia, unspecified

224

186

13.06

227.01

3.3

2.3

0.99

1.13

e9/l

0.90

166

101

ILD, hospital admission 2, with pulmonary infections

209

154

14.31

226.52

2.4

2.3

0.95

1.04

e9/l

0.47

152

Lymphoid leukaemia

208

157

14.64

223.92

3.8

2.3

1.39

1.12

e9/l

1.42

125

Asthma

795

1073

4.02

223.05

2.0

2.5

1.24

1.18

e9/l

0.65

512

634

Azathioprine

313

416

7.83

222.21

2.5

2.7

1.09

1.18

e9/l

0.56

176

261

Asthma, excluding more controls

784

1043

4.05

221.63

2.0

2.5

1.25

1.19

e9/l

0.61

505

615

Pneumonia due to other infectious organisms, not elsewhere classified

153

27.72

219.94

3.1

2.2

0.99

1.11

e9/l

0.46

113

Asthma (only as main-diagnosis)

722

1073

4.11

218.34

1.9

2.5

1.28

1.18

e9/l

1.31

468

634

Asthma (only as main-diagnosis), excluding more controls

714

1043

4.13

216.07

1.9

2.5

1.28

1.19

e9/l

1.04

463

615

Infections, IBD-co-morbidities

311

258

9.05

213.39

3.2

2.3

1.31

1.10

e9/l

1.59

171

166

Asthma (mode)

768

1084

3.93

211.94

2.1

2.5

1.25

1.18

e9/l

0.75

495

638

Pneumocystosis

132

41.65

209.95

3.1

1.9

1.04

0.96

e9/l

0.22

Used for control exclusion in common control thyroid runs

1168

2012

2.97

208.53

2.6

2.4

1.15

1.22

e9/l

1.31

671

1252

Coagulation defects, purpura and other haemorrhagic conditions

383

673

5.92

208.19

3.0

2.5

1.02

1.19

e9/l

2.04

264

407

Dentinal caries

390

713

5.60

201.18

3.0

2.3

1.11

1.15

e9/l

0.37

246

431

Bacterial pneumoniae

503

999

4.54

197.19

2.1

2.4

1.20

1.16

e9/l

0.35

361

592

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

244

161

11.63

197.04

2.3

2.2

0.98

1.18

e9/l

1.15

167

105

L04AD Calcineurin inhibitors

291

414

7.47

195.52

3.5

2.7

1.01

1.28

e9/l

2.98

197

268

Protozoal diseases

145

23.57

194.06

3.0

1.9

1.07

1.20

e9/l

0.48

103

Implicit bacterial Sepsis

478

970

4.61

192.88

2.6

2.3

1.11

1.13

e9/l

0.12

309

602

Systemic connective tissue disorders

498

1168

4.36

192.17

2.3

2.4

1.10

1.18

e9/l

0.83

296

710

Bronchitis

1151

2802

2.72

191.34

2.7

2.3

1.23

1.15

e9/l

1.62

694

1663

COPD differential diagnosis

786

1084

3.67

190.86

2.5

1.21

1.18

e9/l

0.22

473

638

ILD differential diagnosis

786

1084

3.67

190.84

2.5

1.21

1.18

e9/l

0.22

473

638

Other pulmonary diagnosis

788

1092

3.65

190.14

2.5

1.20

1.19

e9/l

0.10

470

649

Excluding asthma or asthma-COPD overlap

785

1092

3.64

188.45

2.5

1.20

1.19

e9/l

0.08

473

649

Mantle cell lymphoma, excluding all cancers (controls excluding all cancers)

105

63.40

186.43

3.2

1.9

1.27

0.82

e9/l

1.78

Bacterial pneumonia, not elsewhere classified

469

926

4.56

185.14

2.1

2.4

1.21

1.16

e9/l

0.43

337

547

ILD, hospital admissions 3, with pneumonia sepsis

182

151

12.73

183.77

2.5

2.3

0.98

1.15

e9/l

0.83

134

Asthma, unspecified (mode)

510

945

4.33

182.57

2.1

2.5

1.20

1.18

e9/l

0.09

322

560

Deposits [accretions] on teeth

215

218

10.20

182.32

4.3

2.6

1.26

1.35

e9/l

0.41

139

130

1152

2239

2.74

181.72

2.5

2.3

1.23

1.14

e9/l

1.77

683

1325

Asthma, unspecified (mode), excluding more controls

506

929

4.33

180.50

2.1

2.5

1.20

1.19

e9/l

0.08

318

550

Oxycodone

448

977

4.53

179.75

2.5

2.3

1.10

e9/l

0.00

281

602

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

164

119

14.51

179.28

2.9

1.9

1.16

1.04

e9/l

0.55

Viral Sepsis

308

521

6.10

173.87

2.6

2.4

1.20

1.23

e9/l

0.12

194

322

Other disorders of white blood cells

169

139

13.15

172.26

3.3

2.4

1.22

1.08

e9/l

0.43

Implicit viral Sepsis

305

519

6.06

171.12

2.6

2.4

1.20

1.23

e9/l

0.17

192

322

Non-invasive ventilation

345

608

5.47

170.36

2.4

2.8

1.17

1.12

e9/l

0.31

271

342

Hodgkin lymphoma

122

25.37

170.23

2.5

2.1

1.02

1.11

e9/l

0.30

Neoplasms

854

1473

3.14

170.06

3.0

2.3

1.16

1.31

e9/l

3.07

536

828

Asthma, hospital admissions 3, pneumonia

490

1242

4.02

169.89

1.9

2.5

1.25

1.16

e9/l

0.96

328

763

Asthma-related pneumonia or sepsis

490

1242

4.02

169.89

1.9

2.5

1.25

1.16

e9/l

0.96

328

763

Persons encountering health services for specific procedures and health care

1163

2837

2.57

169.66

2.3

2.5

1.12

1.22

e9/l

2.48

746

1655

Asthma-related pneumonia

489

1239

4.03

169.65

1.9

2.5

1.25

1.16

e9/l

1.00

328

761

Marginal zone B-cell lymphoma, excluding all cancers (controls excluding all cancers)

52.66

169.59

3.3

1.8

1.20

1.13

e9/l

0.11

Acute sinusitis

619

1707

3.43

167.69

2.7

2.3

1.27

1.17

e9/l

1.68

372

1018

Asthma-related infections

707

2254

3.13

167.26

2.0

2.6

1.29

1.16

e9/l

2.45

475

1332

Asthma, hospital admission 2, infections

707

2254

3.13

167.26

2.0

2.6

1.29

1.16

e9/l

2.45

475

1332

Chronic lymphocytic leukaemia, helper endpoint

104

36.29

164.08

2.5

2.4

1.38

0.95

e9/l

1.32

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

104

36.29

164.08

2.5

2.4

1.38

0.95

e9/l

1.32

Acute upper respiratory infections of multiple and unspecified sites

817

2121

2.92

160.18

2.9

2.3

1.21

1.17

e9/l

0.54

481

1282

Other and unspecified disorders of white blood cells

138

16.43

159.03

3.6

2.2

1.22

1.10

e9/l

0.30

Zoster [herpes zoster]

285

501

5.88

154.71

2.8

2.3

1.15

1.07

e9/l

0.58

178

297

Other respiratory diseases principally affecting the interstitium

278

479

5.99

154.11

2.3

2.1

0.97

1.10

e9/l

1.24

194

287

Optic neuritis

145

112

14.08

153.67

3.6

2.4

1.20

1.24

e9/l

0.16

Hodgkin lymphoma, hilmo

122

18.23

147.08

2.5

2.3

1.02

1.15

e9/l

0.51

Other interstitial pulmonary diseases

249

409

6.31

145.12

2.3

2.0

0.96

1.13

e9/l

1.64

176

237

Acute upper respiratory infections

1032

2598

2.51

145.04

2.6

2.3

1.23

1.15

e9/l

1.48

594

1559

Reimbursement for rheumatic diseases

647

2166

3.02

144.65

2.0

2.6

1.07

1.18

e9/l

1.92

389

1311

ILD, hospital admissions

248

408

6.30

144.33

2.3

2.0

0.96

1.13

e9/l

1.62

176

235

Interstitial lung disease

249

412

6.26

144.06

2.3

2.0

0.96

1.13

e9/l

1.72

176

238

Interstitial lung disease endpoints

249

412

6.26

144.06

2.3

2.0

0.96

1.13

e9/l

1.72

176

238

Bronchiectasis

175

198

9.32

142.32

1.9

2.0

1.25

1.08

e9/l

1.04

102

118

Multiple myeloma and malignant plasma cell neoplasms

109

20.77

142.00

3.0

1.9

1.09

1.00

e9/l

0.25

Multiple myeloma, excluding all cancers (controls excluding all cancers)

108

20.56

140.10

3.0

1.9

1.09

1.00

e9/l

0.26

Use of glatiramer acetate

27.08

139.86

4.1

2.7

1.10

1.23

e9/l

0.40

Cytomegalovirus infection, IBD co-morbidity

113

19.28

138.31

4.4

2.1

1.47

1.11

e9/l

1.41

Mature T/NK-cell lymphomas, hilmo, excluding all cancers

53.64

137.75

3.4

1.6

1.49

0.89

e9/l

—

Cytomegaloviral disease

113

18.85

137.17

4.4

2.1

1.47

1.17

e9/l

1.06

Undetermined asthma

177

216

8.41

134.63

2.0

2.5

1.34

1.12

e9/l

1.88

115

122

Implicit fungal Sepsis

109

18.61

133.92

2.5

2.2

1.19

1.04

e9/l

0.52

Disorders of optic nerve and visual pathways

210

316

6.97

133.70

3.5

2.3

1.33

1.25

e9/l

0.35

110

195

Undetermined asthma, excluding more controls

177

221

8.22

132.12

2.0

2.5

1.34

1.10

e9/l

2.07

115

126

Implicit Sepsis

710

1981

2.82

132.04

2.4

1.12

1.15

e9/l

0.28

442

1179

Diagnoses used for exclusion with ILD

343

808

4.34

131.79

2.3

2.4

1.00

1.15

e9/l

1.91

231

495

548

1749

3.16

131.79

1.9

2.7

1.35

1.21

e9/l

2.51

373

1033

Chronic lymphocytic leukaemia

104

19.63

130.23

2.5

1.8

1.38

0.93

e9/l

1.60

Selective deficiency of immunoglobulin G [IgG] subclasses

55.29

130.12

2.2

1.7

1.35

0.94

e9/l

—

Fungal Sepsis

115

15.63

129.36

2.4

2.2

1.21

1.06

e9/l

0.56

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

971

2751

2.42

129.30

3.1

2.3

1.18

1.20

e9/l

0.21

561

1676

Other special examinations and investigations of persons without complaint or reported diagnosis

675

1117

3.09

128.45

2.6

2.1

1.22

1.09

e9/l

2.00

406

750

Chronic periapical parodontitis

287

599

4.91

128.34

3.0

2.2

1.04

1.12

e9/l

0.71

173

358

Other medical care

442

1234

3.55

128.04

2.2

2.6

1.03

1.16

e9/l

2.03

315

724

Common variable immunodeficiency

54.64

126.93

2.2

1.2

1.07

1.11

e9/l

—

Use of interferon beta-1a

105

18.17

126.19

3.8

2.5

1.03

1.34

e9/l

1.38

Other acute lower respiratory infections

599

1979

2.93

125.40

2.5

1.29

1.18

e9/l

1.74

396

1184

Headache

575

1612

3.01

122.96

2.5

2.2

1.40

1.17

e9/l

4.80

335

935

Medical observation and evaluation for suspected diseases and conditions

657

1117

3.04

122.64

3.0

2.1

1.30

1.09

e9/l

3.77

323

750

Herpesviral [herpes simplex] infections

214

363

6.12

120.86

2.6

1.28

1.21

e9/l

0.38

144

221

All influenza

306

706

4.42

120.70

2.6

1.15

1.19

e9/l

0.21

181

414

Other immunodeficiencies

30.58

120.63

2.6

1.8

1.47

1.26

e9/l

0.44

Unspecified human immunodeficiency virus [HIV] disease

33.95

120.12

5.4

2.2

1.55

0.89

e9/l

3.31

General examination and investigation of persons without complaint and reported diagnosis

633

1117

3.04

120.10

2.9

2.1

1.22

1.09

e9/l

1.72

349

750

Polyarthropathies

732

1832

2.69

120.01

2.2

2.6

1.10

1.14

e9/l

0.39

466

1096

ILD, hospital admissions 1, main diag only

210

352

6.18

119.97

2.2

2.0

0.96

1.13

e9/l

1.75

150

205

Mantle cell lymphoma

40.94

119.65

3.5

2.3

1.19

0.99

e9/l

0.33

Other/unspecified cytomegaloviral diseases

18.75

118.03

4.7

2.0

1.44

1.02

e9/l

1.76

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

23.84

117.28

6.2

3.0

0.99

1.00

e9/l

0.03

Chronic sinusitis

483

1553

3.15

116.42

2.0

2.5

1.30

1.09

e9/l

4.39

282

950

Mature T/NK-cell lymphomas, hilmo

29.16

115.45

3.4

1.9

1.49

1.10

e9/l

0.66

Symptoms and signs involving the skin and subcutaneous tissue

693

2700

2.58

115.32

2.7

2.3

1.23

1.15

e9/l

1.12

387

1649

Asthma and opportunity respiratory infection

119

108

11.80

113.72

1.6

2.1

1.34

0.98

e9/l

2.96

Other systemic involvement of connective tissue (FG)

307

738

4.21

113.55

2.3

2.5

1.16

1.22

e9/l

0.38

190

429

Mycoses

344

911

3.86

112.71

2.6

2.4

1.18

1.17

e9/l

0.05

199

551

Human immunodeficiency virus [HIV] disease

17.11

112.19

5.4

2.4

1.50

1.14

e9/l

1.65

Failure and rejection of transplanted organs and tissues

23.44

112.12

8.9

2.2

0.88

1.07

e9/l

0.50

Viral pneumonia

191

319

6.17

109.40

2.5

2.7

0.95

1.24

e9/l

2.92

129

170

Sarcoidosis

214

405

5.46

107.45

2.4

0.95

1.14

e9/l

1.90

134

241

Other diseases of pleura

445

1251

3.20

106.58

2.3

2.4

1.04

1.13

e9/l

0.85

279

766

Neurological diseases

879

1864

2.39

105.09

2.9

2.3

1.28

1.18

e9/l

1.70

493

1165

Other disorders involving the immune mechanism, not elsewhere classified

103

13.23

104.94

5.5

2.1

1.33

1.20

e9/l

0.39

Diseases of pulp and periapical tissues

385

1153

3.39

104.51

2.9

2.3

1.09

1.12

e9/l

0.22

241

674

Diseases of the respiratory system

561

936

3.03

103.40

2.3

1.18

e9/l

0.04

324

562

Asthma (diagnoses ohter than nonallergic)

831

3138

2.28

102.70

2.0

2.5

1.26

1.16

e9/l

2.12

536

1841

Other and unspecified disorders involving the immune mechanism, not elsewhere classified

13.40

100.56

5.7

2.1

1.35

1.17

e9/l

0.56

Other systemic involvement of connective tissue

324

894

3.69

99.95

2.4

2.3

1.16

1.15

e9/l

0.05

200

539

Other and unspecified dermatitis

519

1897

2.77

99.37

2.7

2.4

1.20

1.14

e9/l

0.54

300

1155

Dermatitis

594

2323

2.59

99.28

2.6

2.4

1.16

1.14

e9/l

0.19

357

1400

Renal failure

421

1244

3.14

98.53

2.5

2.3

1.06

1.14

e9/l

0.71

265

764

Abnormalities of breathing

863

2266

2.28

97.53

2.1

2.5

1.26

1.17

e9/l

1.32

522

1350

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

329

388

4.29

97.52

2.7

2.1

1.23

1.24

e9/l

0.05

187

234

Myeloid leukaemia

23.59

95.81

6.4

1.9

1.17

0.96

e9/l

0.40

Acute bronchitis

440

1472

2.97

95.25

2.5

1.29

1.17

e9/l

1.35

295

887

Multiple myeloma and malignant plasma cell neoplasms

109

114

10.17

94.27

3.0

1.8

1.09

1.00

e9/l

0.37

Direct fill therapy

228

516

4.56

92.70

3.7

2.6

1.16

1.21

e9/l

0.28

156

320

Condition for Implicit Sepsis (Organ dysfunction codes)

736

2321

2.32

91.29

2.4

1.09

1.17

e9/l

1.28

459

1384

Streptococcal septicaemia

126

164

7.94

91.16

2.9

2.5

1.21

1.08

e9/l

0.60

SLE (Finngen)

14.98

91.01

2.5

3.3

0.91

1.13

e9/l

0.81

Dermatitis and eczema

993

3167

2.07

90.86

2.5

2.4

1.25

1.16

e9/l

1.40

592

1903

Explicit bacterial Sepsis

154

250

6.35

90.81

2.8

2.6

1.18

1.15

e9/l

0.14

149

Chronic kidney disease

295

818

3.65

89.56

2.4

2.3

1.09

1.12

e9/l

0.20

181

510

Renal tubulo-interstitial diseases

783

2714

2.23

89.46

2.5

2.4

1.14

1.17

e9/l

0.20

486

1614

Dyspnoea

795

2773

2.21

89.19

2.1

2.5

1.19

1.15

e9/l

0.42

478

1666

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

117

144

8.42

88.74

2.2

1.03

1.19

e9/l

0.81

Provisional assignment of new diseases of uncertain etiology

478

1778

2.72

88.56

2.3

2.5

1.17

1.22

e9/l

0.43

290

1078

Codes for special purposes

478

1780

2.72

88.37

2.3

2.5

1.17

1.22

e9/l

0.43

290

1079

Malaise and fatigue

386

1038

3.13

88.36

2.0

2.2

1.25

1.18

e9/l

0.61

238

610

Neurological diseases, wide definition

351

475

3.75

88.20

3.0

2.1

1.30

e9/l

0.03

196

292

Finngen Rheumatological endpoints

889

2368

2.16

87.05

2.3

2.6

1.17

1.19

e9/l

0.27

562

1390

Cough

413

1381

2.90

85.76

2.7

2.6

1.18

1.16

e9/l

0.13

222

851

Diseases of the skin and subcutaneous tissue

910

2141

2.15

85.04

2.4

1.26

1.13

e9/l

2.56

541

1275

Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)

10.24

84.24

2.1

2.4

1.01

1.27

e9/l

1.13

Osteopathies and chondropathies

512

1906

2.58

84.14

2.5

2.4

1.18

1.15

e9/l

0.23

328

1125

Covid-19 confirmed case

326

1009

3.29

84.13

2.3

2.5

1.20

1.21

e9/l

0.07

200

613

Other viral diseases

375

1259

3.02

83.86

3.4

2.6

1.31

1.27

e9/l

0.28

244

745

Chronic lower respiratory diseases

1089

3001

1.98

83.76

2.1

2.6

1.25

1.16

e9/l

1.82

690

1761

Methotrexate

170

329

5.28

83.08

1.9

2.7

1.00

1.12

e9/l

0.78

107

199

Asthma, hospital admissions , main diagnosis only

759

3171

2.16

82.87

1.9

2.5

1.31

1.15

e9/l

3.85

500

1858

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

21.94

82.69

6.0

1.9

0.84

0.97

e9/l

0.30

Use of fingolimod

25.67

82.43

3.1

2.4

0.93

1.37

e9/l

1.28

Opioids

867

2142

2.14

81.55

2.4

2.3

1.26

1.15

e9/l

2.21

518

1255

Other diseases of hard tissues of teeth

597

1858

2.42

81.47

2.8

2.3

1.21

1.17

e9/l

0.45

362

1095

Gastrointestinal diseases

582

1140

2.58

80.99

2.7

2.4

1.24

1.22

e9/l

0.20

351

679

Other necrotizing vasculopathies (FG)

109

138

8.24

80.91

2.5

2.0

1.12

1.06

e9/l

0.20

Other disorders of teeth and supporting structures

237

611

3.95

80.73

2.7

2.2

1.13

1.11

e9/l

0.13

126

369

Infection due to other mycobacteria

28.93

80.66

2.5

2.0

1.27

0.82

e9/l

—

Other reaction to severe stress, and adjustment disorders

403

1446

2.82

80.13

2.9

2.5

1.31

1.19

e9/l

1.50

244

840

Enterocolitis due to Clostridium difficile

149

268

5.72

79.10

3.0

2.3

1.14

1.11

e9/l

0.12

162

Other necrotizing vasculopathies

121

178

7.07

78.69

2.4

2.0

1.11

1.04

e9/l

0.26

104

Oedema, not elsewhere classified

255

709

3.62

76.97

2.4

2.1

1.15

1.16

e9/l

0.05

141

421

Persons encountering health services for other counselling and medical advice, not elsewhere classified

977

2829

1.98

76.94

2.4

2.5

1.18

1.17

e9/l

0.05

602

1683

Use of teriflunomide

22.20

76.85

2.8

2.5

1.05

1.45

e9/l

1.04

Encephalitis

11.60

76.43

3.1

2.1

1.36

1.01

e9/l

1.67

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

13.34

76.32

2.8

2.5

1.24

1.06

e9/l

0.57

Intestinal infectious diseases

835

3218

2.03

75.80

2.5

2.4

1.25

1.17

e9/l

1.36

518

1914

Myeloid leukaemia

14.49

75.74

6.4

2.0

1.17

1.05

e9/l

0.23

Dentofacial anomalies [including malocclusion]

298

920

3.25

75.63

2.9

2.3

1.31

1.17

e9/l

1.26

201

538

Complications of medical and surgical care

630

2703

2.23

75.43

3.0

2.2

1.20

1.14

e9/l

0.70

383

1612

Other encephalitis

11.82

75.38

3.2

2.1

1.34

1.06

e9/l

1.20

Other disorders of lacrimal gland

350

1204

2.95

75.34

3.0

2.4

1.15

1.16

e9/l

0.10

211

715

Persons encountering health services in other circumstances, wide

1049

2837

1.93

74.88

2.4

2.5

1.13

1.17

e9/l

0.52

647

1685

Inflammatory diseases of the central nervous system

143

263

5.63

74.30

2.6

2.5

1.43

1.17

e9/l

1.79

149

Candidiasis

184

421

4.49

73.78

2.4

2.3

1.23

1.16

e9/l

0.36

112

250

Heart failure, not strict

636

1961

2.26

72.91

2.3

2.5

0.97

1.17

e9/l

5.11

391

1193

Symptoms and signs involving the nervous and musculoskeletal systems

527

2257

2.36

72.41

2.8

2.4

1.31

1.17

e9/l

1.90

353

1342

Systemic lupus erythematosus

10.33

71.95

2.5

0.91

1.13

e9/l

0.90

Other bacterial intestinal infections

207

529

3.99

71.50

2.8

2.5

1.15

1.09

e9/l

0.30

116

323

Dialysis, with operation codes

178

407

4.49

71.50

2.7

2.6

0.98

1.21

e9/l

1.96

113

245

Diseases of the eye and adnexa

776

1837

2.13

71.34

2.8

2.4

1.26

1.19

e9/l

1.05

461

1117

Disorders of lacrimal system

393

1480

2.69

71.23

2.9

2.3

1.14

1.15

e9/l

0.06

236

886

Tramadol

645

1870

2.23

71.18

2.1

2.4

1.25

1.13

e9/l

1.75

395

1113

Parasetamol

707

1649

2.20

70.91

2.4

2.5

1.22

1.17

e9/l

0.67

434

945

Complications of surgical and medical care, not elsewhere classified

821

2954

2.01

70.70

2.8

2.3

1.17

1.16

e9/l

0.11

501

1753

Acute renal failure

212

560

3.86

69.88

2.6

2.2

0.91

1.11

e9/l

2.43

137

349

Seropositive rheumatoid arthritis

249

731

3.45

69.66

2.0

2.4

0.98

1.17

e9/l

2.21

146

440

Symptoms and signs involving the circulatory and respiratory systems

901

2284

1.99

69.44

2.4

2.5

1.27

1.17

e9/l

1.75

536

1361

Osteoporosis

236

638

3.58

69.15

2.4

2.1

1.09

1.06

e9/l

0.18

157

389

Cardiovascular diseases

634

1541

2.26

68.68

2.4

2.8

1.26

1.29

e9/l

0.29

401

882

Idiopathic thrombocytopenic purpura

10.67

67.94

2.8

2.2

1.25

1.14

e9/l

0.22

Cardiovascular diseases (excluding rheumatic etc)

652

1725

2.20

67.48

2.3

2.8

1.23

1.28

e9/l

0.55

419

978

Nephropathy related operations

176

418

4.33

67.38

2.6

0.99

1.20

e9/l

1.63

112

253

Rheumatoid arthritis

312

967

2.97

66.71

2.0

2.4

1.00

1.11

e9/l

1.24

182

584

Bacterial intestinal infections, IBD co-morbidities

205

550

3.80

66.12

2.8

2.5

1.15

1.11

e9/l

0.22

115

340

Infections of the skin and subcutaneous tissue

540

2420

2.24

66.05

2.5

1.22

1.19

e9/l

0.20

326

1456

Examination and observation for other reasons

459

1110

2.53

65.71

2.5

2.1

1.34

1.09

e9/l

3.11

254

745

Human immunodeficiency virus [HIV] disease resulting in other conditions

12.55

65.66

4.8

2.3

1.48

1.20

e9/l

1.12

Diseases of oral cavity, salivary glands and jaws

773

1942

2.05

65.41

2.7

2.2

1.22

1.18

e9/l

0.51

485

1149

SLE, ICD10

9.71

65.41

2.5

0.91

1.19

e9/l

1.22

SLE, strict definition

9.71

65.41

2.5

0.91

1.19

e9/l

1.22

Codeine

770

2088

2.04

65.07

2.3

2.4

1.27

1.14

e9/l

2.62

457

1223

Care involving use of rehabilitation procedures

532

2274

2.24

64.39

2.3

2.6

1.24

1.20

e9/l

0.41

391

1330

Use of dimethyl fumarate

24.79

64.16

3.7

2.7

1.07

1.32

e9/l

0.49

Other symptoms and signs involving the nervous and musculoskeletal systems

400

1600

2.53

64.10

3.0

2.5

1.27

1.21

e9/l

0.53

275

952

Marginal zone B-cell lymphoma

23.83

63.97

3.8

2.2

1.02

0.95

e9/l

0.10

Benign neoplasms

597

1524

2.23

63.64

2.4

2.3

1.15

1.26

e9/l

1.60

346

855

Persons encountering health services for examination and investigation

529

1117

2.39

63.43

2.6

2.1

1.18

1.09

e9/l

1.04

298

750

Other and unspecified aplastic anaemias

21.37

63.26

2.3

1.8

1.08

1.20

e9/l

—

Allergic asthma (mode)

202

543

3.69

62.73

1.9

2.6

1.41

1.17

e9/l

2.72

121

305

Allergic asthma (mode), excluding more controls

202

544

3.68

62.54

1.9

2.6

1.41

1.17

e9/l

2.72

121

308

Abnormal findings on diagnostic imaging of central nervous system

113

7.96

61.96

2.7

2.8

1.24

1.20

e9/l

0.08

Malignant immunoproliferative diseases

26.70

61.92

3.0

1.8

1.27

1.44

e9/l

0.12

Donors of organs and tissues

19.03

61.75

3.9

2.3

0.90

1.31

e9/l

—

Other acute disseminated demyelination

20.96

61.40

5.0

2.3

1.23

1.33

e9/l

0.13

Disorders of other endocrine glands

420

1724

2.42

61.26

2.6

2.5

1.24

1.22

e9/l

0.14

286

1042

Diseases of oesophagus, stomach and duodenum

881

2862

1.88

60.79

2.1

2.5

1.19

1.17

e9/l

0.29

498

1750

Diarrhoea and gastroenteritis of presumed infectious origin

610

2685

2.08

60.76

2.4

2.5

1.24

1.18

e9/l

0.80

384

1594

Malignant neoplasm of eye, brain and central nervous system

113

7.88

60.66

1.9

2.5

1.05

1.10

e9/l

0.17

Defects in the complement system

24.73

60.62

2.4

1.3

1.53

1.17

e9/l

—

Other heart diseases

480

1357

2.36

60.39

2.3

2.9

1.10

1.25

e9/l

2.39

320

768

ILD-related respiratory insufficiency

10.74

58.66

2.1

0.92

1.14

e9/l

0.51

Systemic lupus erythematosus, unspecified

9.88

58.58

2.5

2.7

0.85

1.17

e9/l

1.49

Sulfasalazine

234

740

3.20

58.33

2.0

2.7

1.08

1.20

e9/l

0.79

129

449

Aspergillosis

22.27

58.27

2.6

2.0

1.03

0.81

e9/l

0.58

Adrenocortical insufficiency

8.52

57.70

1.9

2.4

1.31

1.26

e9/l

0.11

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

291

680

2.96

57.66

2.1

1.15

1.04

e9/l

0.99

180

362

Malignant neoplasm of brain

8.96

57.64

1.9

2.5

1.02

1.11

e9/l

0.26

Gout

235

676

3.21

57.51

2.5

2.3

1.05

1.08

e9/l

0.19

151

422

Gout, FINNGEN

235

752

3.16

57.50

2.5

2.2

1.05

1.08

e9/l

0.15

151

461

Pulmonary heart disease, diseases of pulmonary circulation

276

969

2.88

57.31

2.3

1.16

1.12

e9/l

0.20

190

601

Asthma, including avohilmo

977

3191

1.79

56.96

2.0

2.6

1.27

1.15

e9/l

2.92

621

1877

Erysipelas

374

1386

2.48

56.85

2.1

2.3

1.14

1.15

e9/l

0.05

229

830

Asymptomatic human immunodeficiency virus [HIV] infection status

32.85

56.81

4.7

2.5

1.54

0.77

e9/l

—

Other specified/unspecified systemic involvement of connective tissue

153

6.44

56.70

2.1

2.4

1.11

e9/l

0.02

Viral pneumonia (known virus, not influenza)

10.59

56.69

2.9

2.6

1.11

1.20

e9/l

0.19

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

160

323

4.20

56.67

2.0

1.9

0.93

0.99

e9/l

0.40

106

175

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

132

288

4.71

56.34

6.3

2.2

1.06

1.12

e9/l

0.27

171

Mixed connective tissue disease

103

183

5.83

55.63

2.2

2.3

1.10

1.23

e9/l

0.52

107

Rheumatoid arthritis, including avohilmo

337

1331

2.56

55.58

1.9

2.4

1.02

1.17

e9/l

2.25

199

810

Visual disturbances and blindness

440

1960

2.27

55.38

2.6

2.4

1.30

1.18

e9/l

1.44

253

1197

Nutritional anaemias

396

1638

2.37

55.25

2.5

2.3

1.03

1.16

e9/l

1.69

223

990

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

321

811

2.72

54.85

2.1

1.17

1.06

e9/l

1.13

196

432

Early onset COPD, excluding more controls

149

363

4.15

54.84

1.7

2.4

1.19

1.08

e9/l

0.54

226

Nausea and vomiting

260

891

2.91

54.59

2.8

2.6

1.31

1.22

e9/l

0.54

153

546

Other respiratory disorders and diseases

198

590

3.41

54.54

2.3

2.5

1.13

1.10

e9/l

0.12

130

363

Other diseases of the respiratory system

198

590

3.41

54.54

2.3

2.5

1.13

1.10

e9/l

0.12

130

363

Abnormal findings on examination of blood, without diagnosis

403

1622

2.35

54.40

2.5

2.4

1.11

1.13

e9/l

0.16

266

973

Pain, not elsewhere classified

220

704

3.16

53.82

2.2

2.3

1.29

1.25

e9/l

0.23

137

415

Other disorders of skin and subcutaneous tissue

535

2371

2.08

53.69

2.3

2.4

1.19

1.13

e9/l

0.69

316

1433

Disorders of eyelid, lacrimal system and orbit

673

2747

1.93

53.38

2.6

2.4

1.19

1.14

e9/l

0.45

400

1654

Chronic periodontitis

153

389

4.01

53.35

3.1

2.3

1.13

1.08

e9/l

0.23

227

Acquired haemolytic anaemia

11.47

52.66

3.2

1.7

1.08

0.94

e9/l

0.37

Disorders of tooth development and eruption

173

5.78

52.43

4.3

2.8

1.14

1.50

e9/l

1.96

101

Dermatitis due to substances taken internally

142

6.41

52.42

2.7

2.5

1.14

1.10

e9/l

0.11

Other diseases of intestines

891

2908

1.79

52.23

2.4

2.5

1.22

1.19

e9/l

0.38

512

1778

Factors influencing health status and contact with health services

243

370

3.32

52.05

2.6

2.1

1.18

1.08

e9/l

0.82

135

245

Other diseases of lip and oral mucosa

163

441

3.76

52.03

2.6

2.3

1.03

1.10

e9/l

0.46

103

258

Venous thromboembolism

413

1783

2.27

51.89

2.2

2.3

1.10

1.14

e9/l

0.25

269

1057

Stomatitis and related lesions

113

232

5.00

51.86

3.9

2.4

1.09

1.14

e9/l

0.18

134

Chorioretinal inflammation

9.27

51.86

2.4

2.2

1.10

1.20

e9/l

0.27

Drug-induced adrenocortical insufficiency

12.01

51.77

1.6

1.8

1.38

1.32

e9/l

0.08

Visual disturbances

408

1815

2.27

51.59

2.6

2.4

1.30

1.17

e9/l

1.44

237

1107

Pulmonary embolism

250

883

2.87

51.41

2.3

1.16

1.12

e9/l

0.17

174

540

Non-allergic asthma (mode)

152

391

3.89

51.20

1.7

2.4

1.24

1.15

e9/l

0.56

121

226

Pulmonary heart disease

250

886

2.86

51.09

2.3

1.16

1.13

e9/l

0.15

174

543

Respiratory disorders in diseases classified elsewhere

14.80

50.91

2.4

2.0

1.03

1.22

e9/l

0.38

Non-allergic asthma (mode), excluding more controls

152

394

3.86

50.65

1.7

2.4

1.24

1.15

e9/l

0.54

121

232

Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, excluding all cancers (controls excluding all cancers)

29.04

50.59

3.1

1.8

1.41

0.94

e9/l

—

Care involving dialysis

109

222

5.05

50.56

2.5

2.8

0.95

1.17

e9/l

1.11

122

Seropositive rheumatoid arthritis, wide

249

888

2.84

50.37

2.0

2.3

0.98

1.16

e9/l

2.03

146

539

Missing teeth due to accident, extraction or parodontitis

128

298

4.39

50.28

3.1

2.4

1.09

1.08

e9/l

0.06

171

Atypical mycobacterium lung infection

17.90

50.22

2.6

2.1

1.43

1.44

e9/l

0.00

Haemolytic anaemias

7.83

49.59

3.6

2.3

1.18

1.27

e9/l

0.19

Other disorders of skin and subcutaneous tissue, not elsewhere classified

154

415

3.78

49.51

2.5

2.2

1.25

1.10

e9/l

0.73

257

Asthma/COPD (KELA code 203)

765

2980

1.82

49.29

2.0

2.6

1.28

1.16

e9/l

2.49

490

1750

Noninfective enteritis and colitis

421

1932

2.20

49.18

2.4

2.6

1.26

1.20

e9/l

0.48

249

1172

Hernia of abdominal wall, postoperative

123

283

4.40

48.89

2.3

2.0

1.43

1.18

e9/l

0.73

186

Other/unspecified seropositive rheumatoid arthritis

245

881

2.82

48.82

1.9

2.3

0.99

1.16

e9/l

1.82

142

536

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

243

872

2.82

48.62

1.9

2.3

0.99

1.16

e9/l

1.93

140

531

Other arthritis (FG)

270

1024

2.67

48.46

2.1

2.6

1.21

1.20

e9/l

0.02

179

617

Benign neoplasm of colon, rectum, anus and anal canal

309

861

2.58

48.30

2.2

1.08

1.11

e9/l

0.23

165

471

Other specified diseases with participation of lymphoreticular and reticulohistiocytic tissue

31.44

48.28

3.8

3.5

0.94

1.09

e9/l

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

473

2281

2.08

48.19

3.3

2.2

1.19

1.12

e9/l

0.59

285

1362

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

100

197

5.21

48.18

2.6

2.0

1.16

1.07

e9/l

0.42

116

Acute lymphocytic leukaemia, excluding all cancers (controls excluding all cancers)

20.10

48.15

7.6

2.4

1.15

1.68

e9/l

0.95

Acute lymphocytic leukaemia, helper endpoint

20.10

48.15

7.6

2.4

1.15

1.68

e9/l

0.95

Iron deficiency anaemia

339

1421

2.39

48.06

2.5

2.3

1.04

1.17

e9/l

1.43

191

872

Other specified/unspecified arthritis

247

902

2.77

47.77

2.1

2.6

1.21

1.16

e9/l

0.35

163

547

Malignant immunoproliferative diseases

15.31

47.75

3.0

1.9

1.27

1.31

e9/l

0.04

Procreative management

344

1223

2.40

47.74

2.4

2.6

1.29

1.22

e9/l

0.61

225

752

Neurotic, stress-related and somatoform disorders

734

2885

1.82

47.39

2.6

2.4

1.33

1.14

e9/l

4.71

443

1718

Other heart diseases, wide

766

2652

1.80

46.60

2.4

2.6

1.14

1.22

e9/l

1.33

493

1548

Gastro-oesophageal reflux disease

536

2417

1.98

46.49

2.2

2.6

1.27

1.15

e9/l

1.73

285

1481

Symptoms and signs involving the digestive system and abdomen

827

2332

1.79

46.47

2.6

2.4

1.22

1.15

e9/l

1.11

494

1408

Depression medications

248

416

3.02

46.12

2.4

2.2

1.26

1.24

e9/l

0.07

149

213

Anxiety disorders

735

2907

1.80

46.02

2.6

2.4

1.33

1.14

e9/l

4.81

444

1726

Respiratory insufficiency

111

6.69

45.77

1.7

2.5

1.14

1.09

e9/l

0.11

Unspecified acute lower respiratory infection

167

502

3.39

45.52

2.6

1.39

1.14

e9/l

1.91

100

301

Hypothyroidism, levothyroxine purchases

215

393

3.17

45.31

2.2

2.3

1.19

1.25

e9/l

0.32

127

197

Hypothyroidism and >3 levothyroxin purchases

215

393

3.17

45.31

2.2

2.3

1.19

1.25

e9/l

0.32

127

197

Urticaria and erythema

345

1513

2.30

45.25

2.4

2.6

1.32

1.21

e9/l

1.09

201

911

Diseases of spleen

12.36

45.20

2.5

1.5

1.53

0.88

e9/l

1.67

Polyneuropathies and other disorders of the peripheral nervous system

204

694

2.98

45.10

3.2

2.4

1.25

1.11

e9/l

0.93

119

439

Generalized skin eruption due to drugs and medicaments

111

6.77

44.96

2.8

2.7

1.20

1.25

e9/l

0.15

Acute generalized exanthematous pustulosis

124

6.37

44.88

2.9

2.6

1.17

1.26

e9/l

0.30

Recurring oral aphthae

139

5.98

44.35

4.1

2.2

1.18

1.31

e9/l

0.45

Benign neoplasm: Colon

265

773

2.64

44.33

2.3

2.1

1.07

1.08

e9/l

0.08

138

418

6-mercaptopurine

8.32

44.22

3.7

3.1

1.08

1.33

e9/l

0.62

Anxiety disorders, excluding more controls

680

2477

1.83

44.22

2.6

2.3

1.32

1.13

e9/l

4.54

412

1479

Hypothyroidism (congenital or acquired)

214

396

3.13

44.15

2.3

1.20

1.26

e9/l

0.34

124

200

Secondary thrombocytopenia

15.15

43.93

3.0

2.1

0.97

1.04

e9/l

0.09

Other disorders of fluid, electrolyte and acid-base balance

245

895

2.67

43.79

2.0

2.4

1.08

1.13

e9/l

0.32

159

541

Symptoms and signs concerning food and fluid intake

101

217

4.73

43.79

3.0

2.0

1.51

1.32

e9/l

0.62

130

DVT of lower extremities and pulmonary embolism

315

1342

2.36

43.79

2.3

1.14

1.13

e9/l

0.05

209

817

Other disorders of adrenal gland

141

5.91

43.71

2.0

2.5

1.31

1.27

e9/l

0.10

Codeine or tramadol medication

877

2853

1.71

43.63

2.3

1.25

1.13

e9/l

2.46

523

1685

Pneumonia derived septicemia

7.56

43.52

2.5

2.8

1.42

1.09

e9/l

1.00

Glomerular diseases

189

629

3.06

43.50

2.0

2.6

1.09

1.17

e9/l

0.46

112

392

Metabolic disorders

735

2571

1.79

43.47

2.3

2.5

1.18

1.14

e9/l

0.48

474

1508

Idiopathic pulmonary fibrosis

165

5.35

42.71

1.8

2.2

0.94

1.00

e9/l

0.20

Acute lymphocytic leukaemia

15.90

42.68

7.6

2.4

1.15

1.76

e9/l

1.36

Symptoms and signs involving the urinary system

589

2446

1.87

42.46

2.8

2.4

1.18

1.14

e9/l

0.46

323

1498

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

139

389

3.61

42.20

1.6

2.1

0.87

1.03

e9/l

1.57

106

215

Drug-induced osteoporosis with pathological fracture

13.92

42.17

2.0

1.5

1.12

1.16

e9/l

0.06

Acute myeloid leukaemia and myelodysplastic syndromes

13.20

42.16

7.6

1.5

1.04

1.00

e9/l

0.06

Asthma and allergy

119

295

4.03

42.10

1.7

2.8

1.54

1.15

e9/l

3.48

156

Other problems related to primary support group, including family circumstances

168

518

3.23

42.04

4.0

2.5

1.32

1.38

e9/l

0.26

317

Asthma and allergy, excluding more controls

119

297

4.01

41.72

1.7

2.8

1.54

1.17

e9/l

3.10

158

Haemorrhage from respiratory passages

256

938

2.55

41.70

2.4

1.10

1.09

e9/l

0.08

162

590

Osteoporosis with pathological fracture (FG)

120

6.15

41.49

2.3

1.8

1.08

1.07

e9/l

0.01

Leukaemia of unspecified cell type

22.91

41.35

6.5

2.0

1.17

1.09

e9/l

—

Exfoliative dermatitis

16.44

41.33

2.9

2.0

1.54

0.97

e9/l

0.56

Other noninfective gastroenteritis and colitis

242

942

2.60

41.29

2.5

2.6

1.32

1.19

e9/l

0.99

159

576

Other/unspecified rheumatoid arthritis

126

336

3.82

41.21

1.9

2.1

0.97

1.06

e9/l

0.52

214

Viral infections of the central nervous system

100

225

4.56

41.19

2.7

2.2

1.43

1.24

e9/l

0.97

136

Abdominal and pelvic pain

801

2330

1.74

41.09

2.6

2.4

1.21

1.15

e9/l

0.81

476

1406

Sicca syndrome [Sjögren]

101

230

4.50

40.94

2.4

2.2

1.04

1.06

e9/l

0.09

146

Lung cancer and mesothelioma

120

258

4.02

40.55

1.9

2.2

0.93

1.09

e9/l

0.92

166

Acute myeloid leukaemia, excluding all cancers (controls excluding all cancers)

27.57

40.28

6.9

1.3

1.23

0.68

e9/l

—

Acute myeloid leukaemia, helper endpoint

27.57

40.28

6.9

1.3

1.23

0.68

e9/l

—

Other and unspecified iron deficiency

269

1115

2.44

40.16

2.6

2.4

1.08

1.19

e9/l

0.93

155

685

Disturbances of skin sensation

247

985

2.54

40.14

2.7

2.4

1.29

1.18

e9/l

0.77

138

581

Multiple myeloma

10.73

39.84

2.1

1.9

0.99

0.85

e9/l

0.35

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS)

10.73

39.84

2.1

1.9

0.99

0.85

e9/l

0.35

Other skin changes

160

510

3.19

39.68

2.6

2.4

1.25

1.11

e9/l

0.94

318

All influenza (not pneumonia)

143

427

3.40

39.40

2.7

1.18

1.20

e9/l

0.07

232

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

404

1952

2.04

39.08

2.0

2.5

1.26

1.06

e9/l

3.78

248

1200

Ethmoidectomy

146

447

3.33

38.76

2.2

2.5

1.40

1.18

e9/l

1.96

272

Molar incisor enamel hypoplasia, with caries

9.23

38.66

6.3

2.6

1.14

1.63

e9/l

1.84

Temporomandibular joint disorders

155

493

3.19

38.54

1.8

2.4

1.35

1.11

e9/l

1.50

304

FESS (DNB20)

142

429

3.37

38.52

2.2

2.5

1.40

1.16

e9/l

2.05

264

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

105

259

4.15

38.37

2.6

2.3

1.22

1.12

e9/l

0.45

151

Pain in joint

453

1510

2.00

38.31

2.2

2.3

1.25

1.11

e9/l

2.05

258

916

Secondary hypertension

199

4.62

38.20

1.9

3.1

1.09

1.25

e9/l

0.63

113

L01XX Other antineoplastic agents

127

5.76

38.13

2.7

1.8

1.01

1.02

e9/l

0.02

Pneumococcal septicemia

6.99

38.03

2.6

2.7

1.44

1.04

e9/l

1.26

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

243

653

2.58

37.88

2.1

2.0

1.13

1.03

e9/l

0.75

141

347

Extracorporeal dialysis

188

4.78

37.77

2.7

2.4

1.00

1.18

e9/l

0.69

106

Syncope and collapse

264

978

2.41

37.68

2.4

2.2

1.21

1.14

e9/l

0.31

157

570

Malignant neoplasm of mesothelium and soft tissue, excluding all cancers (controls excluding all cancers)

115

5.96

37.47

2.2

2.1

0.86

1.20

e9/l

1.68

Other functional intestinal disorders

350

1583

2.12

37.38

2.5

1.28

1.20

e9/l

0.62

206

992

Other autoimmune haemolytic anaemias

13.04

37.28

3.2

1.6

1.02

0.92

e9/l

0.18

Eosinophilic disease (BM)

17.20

36.89

1.6

2.5

1.24

0.98

e9/l

—

L01XE Protein kinase inhibitors

161

5.07

36.77

4.2

1.9

1.05

1.04

e9/l

0.03

Drug-induced cataract

8.34

36.56

3.7

2.1

1.20

1.24

e9/l

0.08

Biological medication for rheuma

174

613

2.89

36.27

1.8

2.5

1.21

1.22

e9/l

0.06

109

372

Wegener granulomatosis

11.26

36.14

2.2

2.1

1.13

0.92

e9/l

0.46

Respiratory conditions due to other external agents

11.11

36.05

1.9

2.0

0.79

1.09

e9/l

0.99

Dermatopolymyositis (FG)

14.62

35.95

2.0

0.91

1.28

e9/l

0.70

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

22.63

35.94

2.6

1.3

1.40

1.17

e9/l

—

Convulsions, not elsewhere classified

178

628

2.82

35.88

2.8

2.4

1.19

1.26

e9/l

0.42

109

373

Hypoplasia of dental enamel, including avohilmo

7.46

35.83

5.7

3.2

1.02

1.53

e9/l

2.50

Disorders of sclera, cornea, iris and ciliary body

421

2178

1.95

35.80

2.4

1.12

1.17

e9/l

0.52

252

1307

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

242

666

2.51

35.77

2.1

2.0

1.12

1.04

e9/l

0.64

143

355

Other diseases of upper respiratory tract

827

2624

1.65

35.71

2.4

2.5

1.36

1.10

e9/l

7.89

475

1612

Cellulitis

200

763

2.66

35.71

2.5

1.11

1.19

e9/l

0.42

119

467

Pleural effusion

128

380

3.42

35.65

2.2

2.1

0.94

1.07

e9/l

0.73

238

Low back pain

557

2394

1.80

35.61

2.5

2.4

1.23

1.14

e9/l

1.26

326

1427

Hepatomegaly and splenomegaly, not elsewhere classified

13.29

35.54

2.7

2.4

1.17

1.34

e9/l

0.22

Pain in throat and chest

607

2100

1.77

35.28

2.4

2.5

1.18

1.14

e9/l

0.42

385

1248

Other (seronegative) rheumatoid arthritis, wide

171

607

2.86

35.11

1.9

2.4

0.98

1.13

e9/l

1.26

366

Chronic rhinitis, nasopharyngitis and pharyngitis

266

1167

2.30

35.00

1.8

2.6

1.38

1.11

e9/l

4.10

164

722

Nonsuppurative otitis media

235

833

2.47

34.97

2.7

2.5

1.35

1.23

e9/l

0.80

141

485

Other disorders of urethra and urinary system

508

2075

1.84

34.90

2.4

2.3

1.21

1.15

e9/l

0.63

297

1252

Diseases of the musculoskeletal system and connective tissue

475

1232

1.94

34.84

2.6

2.5

1.27

1.24

e9/l

0.19

281

736

Hypertensive diseases (excluding secondary)

436

1290

1.98

34.76

2.1

2.8

1.23

e9/l

0.01

288

722

Diseases of the ear and mastoid process

903

2861

1.60

34.60

2.3

2.5

1.20

1.17

e9/l

0.39

533

1722

Other diseases of pericardium

6.27

34.56

2.2

2.3

0.88

1.08

e9/l

0.81

Other infectious diseases

216

4.26

34.15

2.9

2.3

1.04

1.09

e9/l

0.19

128

Benign neoplasm of other and ill-defined parts of digestive system

112

314

3.61

34.03

2.1

2.2

1.19

1.07

e9/l

0.74

176

Exclusions for E4_PCOS_BROAD

188

713

2.68

34.01

2.6

2.7

1.25

1.22

e9/l

0.16

128

448

Other viral diseases, not elsewhere classified

201

786

2.59

33.99

3.3

2.6

1.35

1.28

e9/l

0.38

141

476

Other soft tissue disorders, not elsewhere classified

709

2626

1.68

33.71

2.3

2.5

1.28

1.17

e9/l

1.78

426

1585

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

115

266

3.64

33.71

1.9

0.93

0.98

e9/l

0.20

149

Budesonide

114

326

3.54

33.66

2.1

2.6

1.06

1.19

e9/l

0.59

195

Presence of other functional implants

372

1303

2.03

33.64

2.0

2.1

1.07

1.10

e9/l

0.23

245

807

Malignant neoplasm of other connective and soft tissue, excluding all cancers (controls excluding all cancers)

7.41

33.61

2.0

1.9

0.78

1.30

e9/l

1.88

9.32

33.57

1.2

2.3

1.45

1.01

e9/l

1.19

Acute tubulo-interstitial nephritis

435

2049

1.89

33.49

2.5

2.4

1.20

1.18

e9/l

0.07

274

1228

135

432

3.17

33.35

2.3

2.5

1.21

e9/l

0.01

110

248

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

366

1135

2.06

33.30

2.4

2.9

1.09

1.19

e9/l

1.06

216

622

Recurring oral aphthae, including avohilmo

142

469

3.08

33.27

3.0

2.4

1.16

1.18

e9/l

0.09

284

Other specific joint derangements/joint disorders

561

2131

1.77

33.23

2.2

2.6

1.24

1.17

e9/l

1.03

328

1264

COPD (mode)

162

445

2.91

32.84

1.8

2.2

1.07

1.13

e9/l

0.27

283

Other complications of surgical and medical care, not elsewhere classified

106

296

3.65

32.54

2.4

2.3

1.14

1.11

e9/l

0.11

180

Disorders of mineral metabolism

233

4.04

32.50

2.2

2.4

1.03

1.13

e9/l

0.39

141

Postprocedural disorders of nervous system

251

3.91

32.47

2.5

2.4

1.14

1.31

e9/l

0.89

151

Antihypertensive medication - note that there are other indications

545

1668

1.80

32.21

2.3

2.7

1.26

1.22

e9/l

0.34

347

960

Diseases of salivary glands

154

543

2.87

32.02

2.7

2.3

1.31

1.12

e9/l

0.83

320

Vocal cord dysfunction

118

327

3.39

32.01

1.8

3.1

1.24

1.23

e9/l

0.03

206

Other and unspecified polyneuropathies, also in other diseases

161

584

2.79

31.80

3.0

2.3

1.32

1.08

e9/l

1.66

357

Acute myeloid leukaemia

15.93

31.71

6.9

1.5

1.23

0.92

e9/l

—

Disorders of calcium metabolism

166

4.63

31.61

2.3

2.4

1.02

1.15

e9/l

0.44

5-aminosalicylic acid

162

592

2.76

31.48

1.9

2.9

1.12

1.20

e9/l

0.29

344

Neuromuscular dysfunction of bladder

262

3.78

31.29

3.1

2.3

1.39

1.12

e9/l

1.35

155

Melanocytic naevi

186

731

2.57

31.24

2.4

2.3

1.12

1.23

e9/l

0.80

117

403

Leukaemia of unspecified cell type

13.17

31.23

6.5

2.3

1.17

1.28

e9/l

0.11

Pain (limb, back, neck, head abdominally)

578

1653

1.76

31.23

2.7

2.4

1.28

1.14

e9/l

1.99

347

1014

Heart failure,strict

343

1224

2.04

31.22

2.2

2.3

0.89

1.13

e9/l

5.15

215

741

Noninfectious colitis NAS

134

445

3.06

31.11

2.6

2.5

1.29

1.18

e9/l

0.60

275

Malignant neoplasm, without specification of site, excluding all cancers (controls excluding all cancers)

7.61

31.01

2.9

2.5

1.06

0.97

e9/l

0.24

Osteonecrosis

141

4.95

31.01

2.7

2.0

1.03

1.12

e9/l

0.35

Episodal and paroxysmal disorders

857

2793

1.58

30.94

2.3

2.5

1.27

1.17

e9/l

1.55

524

1687

Conjunctivitis (acute, non atopic)

258

1174

2.21

30.93

2.4

2.6

1.25

e9/l

0.02

164

696

Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

88.79

30.92

1.8

1.2

1.02

—

e9/l

—

In situ neoplasms

190

721

2.53

30.78

2.2

1.17

1.20

e9/l

0.12

119

387

Lung diseases due to external agents

119

371

3.25

30.71

2.0

2.2

1.06

1.12

e9/l

0.27

219

Glomerular disorders in diseases classified elsewhere

116

357

3.31

30.64

1.9

2.6

1.04

1.08

e9/l

0.20

208

Other and unspecified drugs and medicaments

248

3.83

30.59

2.6

2.4

1.25

1.17

e9/l

0.28

144

Localized swelling, mass and lump of skin and subcutaneous tissue

250

1133

2.23

30.52

2.9

2.4

1.11

1.17

e9/l

0.40

120

703

Obesity related asthma

255

1165

2.21

30.51

1.9

2.5

1.37

1.17

e9/l

2.23

167

691

Abnormal findings on diagnostic imaging of other body structures

113

343

3.35

30.49

2.8

2.2

1.07

1.19

e9/l

0.61

220

Other symptoms and signs involving the digestive system and abdomen

140

483

2.93

30.34

3.1

2.5

1.37

1.19

e9/l

0.79

299

Viral pneumonia (unknown virus, not influenza)

211

4.08

30.07

2.6

2.4

0.97

1.27

e9/l

1.77

123

Acute suppurative otitis media

258

1109

2.19

29.94

2.8

2.6

1.41

1.28

e9/l

1.02

158

656

Tumor necrosis factor alpha inhibitors

152

554

2.79

29.83

1.9

2.5

1.16

1.22

e9/l

0.25

337

Erosion of teeth

8.07

29.65

3.0

2.5

1.36

1.40

e9/l

0.05

Other disorders of optic [2nd] nerve and visual pathways

193

4.20

29.38

3.6

2.4

1.53

1.26

e9/l

0.83

118

Benign neoplasm: Colon, unspecified

120

386

3.12

29.06

2.4

2.1

0.95

1.03

e9/l

0.49

215

Cutaneous abscess, furuncle and carbuncle

218

956

2.30

28.86

2.1

2.6

1.20

1.21

e9/l

0.05

138

573

Disorders of lens

474

1676

1.79

28.84

2.4

1.13

1.11

e9/l

0.18

282

1010

Diseases of middle ear and mastoid

462

2141

1.78

28.72

2.5

2.4

1.25

1.23

e9/l

0.11

278

1271

Malignant neoplasm of other connective and soft tissue

7.88

28.67

2.1

1.8

0.80

1.13

e9/l

0.74

Dermatopolymyositis

9.74

28.55

2.1

1.9

0.98

1.15

e9/l

0.33

Other diseases of urinary system

755

2688

1.59

28.51

2.8

2.3

1.22

1.16

e9/l

0.69

449

1630

Gingivitis and periodontal diseases

616

1902

1.68

28.48

2.6

2.2

1.27

1.15

e9/l

1.84

380

1124

Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

9.63

28.48

3.0

2.0

0.90

1.43

e9/l

0.94

Brain glioblastoma and astrocytoma, excluding all cancers (controls excluding all cancers)

12.16

28.46

1.4

1.9

0.90

1.11

e9/l

0.46

COPD, hospital admissions 3, with asthma pneumonia sepsis

190

662

2.46

28.33

1.8

2.1

1.14

1.07

e9/l

0.39

109

412

Viral warts

108

335

3.28

28.22

2.4

2.6

1.18

1.25

e9/l

0.31

192

Iridocyclitis

193

811

2.41

28.20

2.1

2.5

1.10

1.16

e9/l

0.39

110

486

Chronic iridocyclitis

129

4.93

28.19

2.1

2.3

1.10

1.22

e9/l

0.47

Complications of procedures, not elsewhere classified

547

2825

1.68

28.14

2.1

2.3

1.21

1.15

e9/l

0.64

337

1670

Dysphagia

179

729

2.48

27.99

2.2

2.3

1.17

1.13

e9/l

0.18

104

454

Pneumonia due to Streptococcus pneumoniae

5.81

27.81

2.7

2.4

1.20

1.23

e9/l

0.07

Anaemia in chronic diseases classified elsewhere

7.59

27.77

2.0

0.94

1.07

e9/l

0.31

Hypoparathyroidism

5.60

27.59

1.6

1.9

1.10

1.15

e9/l

0.12

Other and unspecified tonsillitis

262

1056

2.12

27.54

2.6

2.5

1.30

1.25

e9/l

0.36

168

612

Hypothyroidism, strict autoimmune

427

1562

1.82

27.51

2.2

2.3

1.13

1.19

e9/l

0.56

253

968

Drug-induced osteoporosis

11.10

27.44

2.1

1.00

1.19

e9/l

0.34

Urticaria

258

1236

2.11

27.43

2.5

2.7

1.41

1.24

e9/l

1.66

145

735

Systemic sclerosis (FG)

7.90

27.36

1.9

2.6

0.98

1.03

e9/l

0.08

Seronegative rheumatoid arthritis

102

311

3.33

27.36

2.0

2.5

1.04

1.14

e9/l

0.54

182

Molar incisor enamel hypoplasia

196

4.11

27.35

4.8

3.1

1.12

1.56

e9/l

2.61

131

Other overlap syndromes

9.84

27.26

2.2

0.82

1.06

e9/l

0.49

Dorsalgia

733

2517

1.58

27.24

2.4

1.25

1.14

e9/l

1.93

436

1506

Arthropathies

705

2247

1.60

27.20

2.3

2.6

1.24

1.18

e9/l

0.66

440

1339

Other benign neoplasms of skin

189

783

2.38

27.13

2.0

2.2

1.17

e9/l

0.01

118

419

Postzoster neuralgia

10.25

27.03

3.0

1.8

0.91

1.02

e9/l

0.20

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

162

4.31

26.92

2.2

2.0

0.99

1.07

e9/l

0.25

Etanercept

215

3.86

26.91

1.7

2.8

1.12

1.26

e9/l

0.61

128

Other and unspecified disorders of skin and subcutaneous tissue

171

4.24

26.90

3.1

2.0

1.69

1.08

e9/l

1.61

105

Childhood asthma (age<16), excluding more controls

110

271

3.25

26.88

2.1

2.8

1.32

1.23

e9/l

0.43

142

Chronic myeloproliferative disease

10.65

26.77

5.2

1.5

0.47

1.08

e9/l

2.09

Childhood asthma (age<16)

110

272

3.24

26.74

2.1

2.8

1.32

1.23

e9/l

0.43

142

Bleeding

566

2502

1.65

26.57

2.4

1.08

1.15

e9/l

0.97

353

1511

Pericarditis

6.14

26.50

2.3

2.8

0.99

1.08

e9/l

0.24

Lower back pain or/and sciatica

717

3196

1.56

26.47

2.4

2.3

1.24

1.14

e9/l

1.83

430

1895

Suppurative and unspecified otitis media

311

1427

1.95

26.08

2.7

2.5

1.35

1.23

e9/l

1.17

190

845

Systemic sclerosis

7.45

26.03

1.9

2.2

0.98

1.09

e9/l

0.23

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

130

4.66

25.85

2.0

1.8

1.18

0.95

e9/l

1.12

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

181

4.02

25.68

2.3

1.9

0.98

1.05

e9/l

0.25

105

Eosinophilia

9.10

25.63

1.7

2.0

1.15

0.82

e9/l

0.70

Heart failure and antihypertensive medication

201

570

2.35

25.54

2.5

2.6

0.90

1.07

e9/l

1.77

127

337

Complications following infusion, transfusion and therapeutic injection

9.87

25.52

3.7

2.5

1.19

1.08

e9/l

0.17

Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue

11.72

25.45

2.6

1.7

1.40

1.18

e9/l

0.30

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

212

3.68

25.42

1.7

1.8

0.87

1.01

e9/l

0.81

125

Hypertension

589

2048

1.63

25.19

2.1

2.6

1.18

1.19

e9/l

0.09

383

1152

Mood disorders, excluding more controls

673

2609

1.58

25.19

2.5

2.3

1.26

1.12

e9/l

2.68

385

1556

Hypertensive diseases

590

2054

1.63

25.14

2.1

2.7

1.18

1.19

e9/l

0.09

384

1157

Disorders of ocular muscles, binocular movement, accommodation and refraction

370

2044

1.81

25.12

2.9

2.5

1.30

1.23

e9/l

0.83

242

1241

18.53

25.02

3.2

2.1

0.75

0.99

e9/l

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

199

681

2.29

24.98

2.2

2.1

1.11

1.06

e9/l

0.24

138

358

ILD and respiratory illness in diseases classified elsewhere

16.70

24.95

3.1

1.9

0.74

1.30

e9/l

—

Other abnormal findings of blood chemistry

111

5.00

24.95

2.4

2.1

1.04

1.07

e9/l

0.10

Lack of expected normal physiological development

5.88

24.92

4.4

2.0

1.55

1.76

e9/l

0.41

Other neurological diseases

474

2260

1.69

24.92

2.5

2.4

1.13

e9/l

0.03

294

1343

Nerve, nerve root and plexus disorders

724

2965

1.54

24.66

2.3

2.4

1.16

1.15

e9/l

0.09

431

1760

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

251

1226

2.04

24.59

3.5

2.5

1.41

1.30

e9/l

0.67

146

734

Unspecified kidney failure

224

3.63

24.53

2.6

2.2

1.08

1.11

e9/l

0.08

130

Disorders of conjunctiva

590

3114

1.59

24.51

2.3

2.5

1.28

1.19

e9/l

1.28

365

1852

Abnormality of white blood cells, not elsewhere classified

10.61

24.51

4.5

1.9

1.04

1.42

e9/l

0.57

Migraine

367

1735

1.81

24.48

2.2

2.5

1.33

1.20

e9/l

1.48

218

1045

Glomerulonephritis

105

351

3.04

24.25

2.1

2.6

1.10

1.19

e9/l

0.44

210

Cerebrovascular diseases (FINNGEN)

227

757

2.16

24.24

2.2

2.9

1.17

1.15

e9/l

0.09

137

413

Inflammatory bowel disease

257

1289

2.01

24.17

2.2

2.6

1.18

1.20

e9/l

0.08

132

765

Kidney transplant status

195

3.85

24.12

2.2

2.8

1.10

1.27

e9/l

0.55

114

Pain in limb

558

2506

1.62

24.07

2.5

1.25

1.17

e9/l

1.00

336

1519

Hypertension, essential

552

1928

1.64

24.05

2.1

2.6

1.18

1.15

e9/l

0.29

356

1070

Myasthenia gravis

7.79

23.99

3.3

1.8

1.10

1.14

e9/l

0.07

Subjective visual disturbances

190

853

2.25

23.90

2.5

1.39

1.17

e9/l

1.48

108

510

Other pleural conditions

228

3.56

23.89

2.3

2.2

0.86

1.11

e9/l

1.68

137

Combined immunodeficiencies

11.06

23.80

3.8

1.8

1.25

0.91

e9/l

0.55

COPD, hospital admission 2, with asthma infections

210

829

2.18

23.73

1.8

2.2

1.15

1.08

e9/l

0.39

121

510

Diseases of the digestive system

313

1684

1.87

23.67

2.4

2.5

1.07

1.17

e9/l

1.12

196

1022

Systemic sclerosis, icd10

6.69

23.62

1.9

2.2

0.98

1.14

e9/l

0.39

Continuous positive airway pressure

154

540

2.48

23.54

2.3

2.7

1.56

1.21

e9/l

1.53

307

Special screening examination for infectious and parasitic diseases

168

523

2.42

23.54

2.1

1.45

1.17

e9/l

1.78

324

Dental operations

441

1305

1.74

23.35

2.6

2.1

1.18

e9/l

0.00

275

751

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

164

4.01

23.11

2.3

1.8

0.98

1.05

e9/l

0.28

Malignant neoplasm of mesothelium and soft tissue

103

4.98

23.05

2.5

2.0

0.84

1.12

e9/l

1.16

Hypoplasia of dental enamel , including avohilmo

186

3.91

23.05

5.1

3.1

1.05

1.52

e9/l

3.14

125

Use of hypnotics and sedatives

745

2862

1.51

22.92

2.4

1.19

1.15

e9/l

0.38

437

1712

Endocrine, nutritional and metabolic diseases

642

2087

1.57

22.91

2.5

2.6

1.27

1.19

e9/l

0.91

397

1187

Meningitis

140

4.31

22.86

1.9

2.4

1.63

1.18

e9/l

1.55

Mood disorders

725

3166

1.51

22.79

2.5

2.4

1.27

1.14

e9/l

2.35

416

1903

Carrier of infectious disease

6.11

22.78

2.3

1.24

1.16

e9/l

0.16

Polyarteritis nodosa and related conditions

7.87

22.73

1.8

2.4

1.21

1.38

e9/l

0.26

Disorders of thyroid, IBD co-morbidities

114

288

2.90

22.71

2.4

2.0

1.19

e9/l

0.00

181

Constipation

600

2754

1.57

22.66

2.2

2.5

1.13

1.17

e9/l

0.36

362

1659

Heart failure, strict

350

1401

1.81

22.63

2.2

2.3

0.89

1.11

e9/l

4.73

219

850

Polyuria

169

740

2.31

22.59

3.1

2.2

1.28

1.11

e9/l

1.46

468

Acute lymphadenitis

190

3.76

22.56

3.1

2.7

1.15

1.23

e9/l

0.27

115

Depression

679

3078

1.52

22.55

2.6

2.4

1.26

1.14

e9/l

1.95

389

1852

Viral meningitis

106

4.85

22.32

2.9

2.4

1.45

1.26

e9/l

0.64

Mood [affective] disorders

721

3164

1.50

22.31

2.5

2.4

1.27

1.14

e9/l

2.38

412

1903

Small fibre neuropathy

6.12

22.29

3.8

2.1

1.24

1.21

e9/l

0.05

Anterior Iridocyclitis

167

732

2.31

22.29

2.1

2.5

1.08

1.17

e9/l

0.61

438

Other specified/unspecified necrotizing vasculopathies

9.47

22.27

2.8

1.9

1.03

1.22

e9/l

0.29

Viral encephalitis, not elsewhere classified/unspecified

7.08

22.24

2.4

1.8

1.48

1.33

e9/l

0.24

Disorders of oesophagus in diseases classified elsewhere

7.86

22.23

1.6

2.1

1.26

1.17

e9/l

0.12

Ulcerative colitis, NAS

133

529

2.55

22.05

2.0

2.4

1.17

1.15

e9/l

0.09

317

Genitourinary diseases

486

1467

1.67

21.97

3.0

2.4

1.24

1.19

e9/l

0.52

292

879

Acute pharyngitis

126

485

2.61

21.96

2.5

2.6

1.26

1.22

e9/l

0.15

283

Suppurative and necrotic conditions of lower respiratory tract

141

4.21

21.78

1.7

2.4

1.06

0.98

e9/l

0.29

Persons encountering health services in other circumstances

268

1413

1.91

21.75

2.3

2.6

1.24

1.21

e9/l

0.21

134

854

Persons with potential health hazards related to communicable diseases

319

1763

1.81

21.75

2.7

2.5

1.33

1.27

e9/l

0.45

217

1022

Crohn's disease NAS

200

3.62

21.67

2.3

2.8

1.04

1.16

e9/l

0.35

114

Adalimumab

322

3.00

21.48

2.1

2.8

1.13

1.25

e9/l

0.59

188

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

5.32

21.36

2.9

2.1

1.07

1.03

e9/l

0.10

Disorders of parathyroid gland

139

565

2.45

21.32

2.1

2.2

1.05

1.09

e9/l

0.15

341

Diplopia

110

405

2.75

21.31

2.7

2.4

1.24

1.10

e9/l

0.85

252

All-cause Heart Failure

342

1387

1.79

21.30

2.2

2.3

0.89

1.12

e9/l

5.34

212

840

Later onset COPD, excluding more controls

247

3.05

21.23

1.8

2.1

1.05

1.03

e9/l

0.06

163

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

378

2227

1.71

21.16

2.2

2.3

1.21

1.13

e9/l

0.72

236

1335

Myocarditis

115

4.52

21.05

2.1

3.2

1.13

1.22

e9/l

0.24

Soft tissue disorders

766

2696

1.48

21.00

2.5

1.26

1.17

e9/l

1.58

461

1625

Otitis media, unspecified

119

420

2.64

20.94

3.0

2.6

1.40

1.27

e9/l

0.58

246

Epilepsy

238

1223

1.95

20.77

2.4

2.7

1.13

1.21

e9/l

0.71

144

749

Benign neoplasms

709

2656

1.50

20.72

2.4

1.12

1.18

e9/l

0.88

414

1591

Hypokalaemia

318

2.96

20.67

1.7

2.4

1.24

1.10

e9/l

0.53

194

Collagenous colitis

256

3.22

20.64

2.3

2.4

1.33

1.16

e9/l

0.56

158

Diseases of the myoneural junction and muscle

101

362

2.83

20.61

2.7

2.5

1.14

1.09

e9/l

0.21

220

Hypo-osmolality and hyponatraemia

120

468

2.58

20.57

2.4

1.03

1.09

e9/l

0.30

292

Myeloproliferative diseases

222

3.39

20.51

3.9

2.0

0.80

1.10

e9/l

1.71

131

Papulosquamous disorders

273

1479

1.86

20.47

2.1

2.5

1.17

e9/l

0.03

193

874

Non-ischemic cardiomyopathy

198

778

2.10

20.46

2.4

2.3

0.97

1.10

e9/l

1.19

123

464

Atrial fibrillation and flutter

218

695

2.06

20.31

2.5

3.0

1.02

1.11

e9/l

0.63

150

376

Volume depletion

224

3.35

20.20

1.9

2.5

1.00

1.17

e9/l

0.68

134

Diseases of liver

240

1253

1.93

20.19

2.1

2.5

1.11

1.18

e9/l

0.46

134

764

Other dorsopathies, not elsewhere classified

715

2544

1.49

20.15

2.3

2.4

1.28

1.14

e9/l

2.69

413

1523

Other meningitis

7.06

20.13

2.3

2.0

1.59

1.03

e9/l

1.11

Brain glioblastoma and astrocytoma

7.58

20.09

1.4

2.3

0.90

1.16

e9/l

0.71

Dental caries 1 and operation codes

602

2007

1.54

20.06

2.5

2.2

1.25

1.16

e9/l

1.17

373

1188

Acute and subacute iridocyclitis

153

677

2.28

20.03

2.1

2.5

1.07

1.16

e9/l

0.59

408

Valvular heart disease excluding rheumatic fever

307

1248

1.81

19.97

2.4

2.6

1.02

1.17

e9/l

1.21

190

748

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

292

3.00

19.94

1.5

1.9

0.82

1.03

e9/l

1.96

167

Other diseases of jaws

178

3.65

19.91

2.6

2.5

1.23

1.06

e9/l

0.45

Conjunctivitis

526

2961

1.55

19.91

2.4

2.5

1.28

1.20

e9/l

0.98

318

1765

Other antidepressants

723

2557

1.48

19.84

2.3

2.4

1.22

1.13

e9/l

1.50

433

1529

Chronic ulcer of skin, not elsewhere classified

170

3.71

19.71

2.1

1.9

1.06

1.08

e9/l

0.06

COPD

264

1169

1.87

19.69

1.7

2.4

1.10

1.09

e9/l

0.06

158

704

Other joint disorders

628

2209

1.52

19.63

2.3

2.5

1.29

1.18

e9/l

1.78

375

1314

Rash and other nonspecific skin eruption

312

2.93

19.56

3.0

2.3

1.25

1.19

e9/l

0.22

188

Congenital malformations, deformations and chromosomal abnormalities

433

2585

1.61

19.43

2.4

2.5

1.28

1.23

e9/l

0.49

275

1526

Crohn disease

121

490

2.50

19.38

2.3

2.6

1.14

1.16

e9/l

0.06

288

Other disorders of gingiva or/and edentulous alveolar ridge

123

4.23

19.38

2.8

2.3

1.34

1.21

e9/l

0.30

225

1094

1.95

19.30

2.1

1.06

e9/l

0.01

141

665

Covid-19 suspected case

173

818

2.13

19.23

2.3

2.7

1.18

1.22

e9/l

0.19

108

481

Vasomotor and allergic rhinitis

274

1495

1.82

19.12

2.0

2.7

1.40

1.14

e9/l

4.20

168

910

Senile cataract

388

1437

1.68

19.07

2.3

2.4

1.12

1.08

e9/l

0.37

234

876

Chronic periodontitis, complicated

296

2.95

18.97

3.5

2.3

1.15

1.08

e9/l

0.30

175

Functional dyspepsia

184

897

2.07

18.85

2.1

2.5

1.18

1.16

e9/l

0.12

108

560

Erythema multiforme

6.09

18.82

2.2

2.3

1.27

1.39

e9/l

0.19

Myalgia

171

812

2.12

18.80

2.1

2.5

1.42

1.17

e9/l

1.70

486

Ocular pain

245

3.15

18.78

3.1

2.7

1.36

1.21

e9/l

0.64

150

Chronic diseases of tonsils and adenoids

556

2312

1.53

18.50

2.6

1.44

1.12

e9/l

6.48

306

1412

Other metabolic disorders

111

442

2.54

18.44

3.3

2.5

1.26

1.17

e9/l

0.38

267

Iron deficiency anaemia secondary to blood loss (chronic)

113

454

2.51

18.40

1.8

2.3

0.91

1.11

e9/l

1.59

272

Malignant neoplasm of bone and articular cartilage of other and unspecified sites, excluding all cancers (controls excluding all cancers)

9.62

18.36

1.8

2.0

0.84

1.34

e9/l

0.54

Non-rheumatic valve diseases

296

1221

1.78

18.33

2.4

2.6

1.03

1.15

e9/l

0.92

183

726

Postprocedural endocrine and metabolic disorders, not elsewhere classified

102

391

2.64

18.32

3.0

2.4

1.27

1.18

e9/l

0.33

240

Other diseases of spinal cord

5.28

18.25

4.2

2.2

1.02

1.09

e9/l

0.21

Other and unspecified diseases of blood and blood-forming organs

6.26

18.21

2.1

2.0

1.37

1.12

e9/l

0.47

Hypothyroidism, drug reimbursement

229

2.89

18.18

2.2

2.3

0.93

1.21

e9/l

2.35

116

Vasculitis limited to skin, not elsewhere classified

5.87

18.15

2.9

1.7

1.12

1.06

e9/l

0.10

Gingival hyperplasia

5.00

18.12

3.2

2.5

1.43

1.21

e9/l

0.48

Other forms of systemic lupus erythematosus

10.18

18.09

2.4

2.0

0.74

0.88

e9/l

—

Malignant neoplasm of heart, mediastinum and pleura, excluding all cancers (controls excluding all cancers)

8.27

18.00

2.4

2.8

1.08

1.10

e9/l

0.04

Disorders of skin appendages

336

2007

1.68

17.98

2.3

2.5

1.24

1.19

e9/l

0.40

200

1211

Other and unspecified urticaria

164

781

2.12

17.95

2.3

2.7

1.41

1.22

e9/l

1.39

473

Skin changes due to chronic exposure to nonionizing radiation

207

1010

1.95

17.93

2.0

1.06

1.05

e9/l

0.06

129

621

Follow-up examination after treatment for conditions other than malignant neoplasms

242

842

1.89

17.84

2.7

2.1

1.36

1.11

e9/l

1.74

104

565

Psychiatric diseases

773

2714

1.43

17.73

2.7

2.3

1.25

1.14

e9/l

1.88

466

1619

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

164

3.58

17.63

3.2

2.3

1.16

e9/l

0.01

Benign neoplasm: Rectum

286

2.89

17.61

1.8

2.0

1.15

1.04

e9/l

0.45

159

Any mental disorder

779

2744

1.43

17.55

2.7

2.3

1.25

1.13

e9/l

1.97

466

1640

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

623

2764

1.47

17.50

2.3

2.4

1.06

1.17

e9/l

1.95

385

1644

Seropositive rheumatoid arthritis, strict definition

116

484

2.42

17.45

2.3

2.4

1.00

1.14

e9/l

0.78

292

Disorders resulting from impaired renal tubular function

103

4.39

17.45

2.3

1.21

1.05

e9/l

0.36

Somatoform disorder

129

564

2.31

17.45

2.0

2.5

1.45

1.16

e9/l

1.70

343

Abnormal results of function studies

246

3.05

17.37

2.4

2.5

1.36

1.15

e9/l

0.62

151

Diseases of arteries, arterioles and capillaries (FINNGEN)

162

528

2.16

17.36

2.0

2.9

0.96

1.11

e9/l

1.23

289

Dorsopathies

730

2597

1.44

17.36

2.4

1.24

1.15

e9/l

1.50

436

1561

Actinic keratosis

200

980

1.95

17.32

2.0

1.02

1.05

e9/l

0.17

127

606

Irritable bowel syndrome

191

974

1.97

17.30

2.2

2.5

1.40

1.19

e9/l

2.01

103

584

Simple and mucopurulent chronic bronchitis

112

4.19

17.29

1.8

2.6

1.63

1.10

e9/l

1.81

Spondyloarthritis

119

505

2.37

17.20

1.6

2.2

1.08

1.20

e9/l

0.72

298

Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

6.51

17.16

3.3

1.5

0.99

1.04

e9/l

0.11

Use of amantadine

6.86

17.16

4.7

1.7

1.29

1.18

e9/l

0.18

Viral and other specified intestinal infections

174

840

2.04

17.16

2.8

2.7

1.28

1.24

e9/l

0.20

120

500

Other and unspecified vasculitis limited to skin

6.07

17.08

2.9

1.7

1.16

1.01

e9/l

0.25

Spondylopathies

505

2006

1.53

17.07

2.1

2.4

1.20

1.10

e9/l

1.10

312

1205

Cardiac arrhythmias

448

1895

1.57

16.97

2.3

2.7

1.16

1.18

e9/l

0.15

296

1075

Other chronic obstructive pulmonary disease

247

1134

1.82

16.96

1.7

2.4

1.13

1.08

e9/l

0.27

144

687

Drug-induced systemic lupus erythematosus

10.78

16.92

1.8

0.95

1.24

e9/l

—

Other specified and unspecified retinal disorders

4.70

16.89

2.8

1.9

0.89

1.15

e9/l

0.91

Nonpyogenic thrombosis of intracranial venous system

8.66

16.83

2.4

2.1

1.21

1.18

e9/l

0.04

Other CVD (FINNGEN)

191

3.08

16.71

1.6

2.4

1.21

1.05

e9/l

0.52

111

Abnormalities of heart beat

208

1094

1.89

16.70

2.0

2.6

1.20

1.12

e9/l

0.55

120

663

Acute bronchiolitis

303

2.73

16.69

3.3

3.2

1.31

1.38

e9/l

0.22

183

Suggestive for eosinophilic asthma

280

2.86

16.56

1.9

2.5

1.48

1.12

e9/l

2.01

160

All anxiety disorders

420

2163

1.57

16.51

2.4

2.5

1.37

1.17

e9/l

3.55

247

1283

Other disorders of ear

607

2778

1.46

16.48

2.4

2.5

1.18

1.15

e9/l

0.35

366

1672

Other gastritis (incl. Duodenitis)

147

696

2.13

16.35

2.1

2.4

1.14

1.13

e9/l

0.04

102

443

Weight loss

299

2.78

16.31

2.8

2.5

1.49

1.18

e9/l

1.05

183

Other malignant neoplasms of skin (=non-melanoma skin cancer)

296

1374

1.71

16.25

2.0

2.2

1.17

1.05

e9/l

1.15

185

844

Other disorders of eye and adnexa

113

482

2.37

16.23

3.0

2.3

1.32

1.22

e9/l

0.54

292

Symptoms and signs involving speech and voice

219

1195

1.84

16.19

1.9

2.4

1.21

1.17

e9/l

0.22

142

713

Chronic myeloid leukaemia, excluding all cancers (controls excluding all cancers)

12.90

16.14

4.4

2.4

0.88

0.76

e9/l

—

Fentanyl

204

3.17

16.11

2.3

2.0

1.15

1.00

e9/l

0.49

124

Dialysis

137

3.74

16.04

2.4

2.6

1.07

1.20

e9/l

0.26

Malignant neoplasm of small intestine

6.34

16.03

3.3

1.8

0.97

0.89

e9/l

0.18

Abnormal weight loss

276

2.83

15.84

2.5

2.4

1.46

1.17

e9/l

0.84

166

Dental caries 3 and operation codes

613

2160

1.46

15.84

2.5

2.3

1.26

1.16

e9/l

1.27

368

1290

Rheumatism, unspecified

103

426

2.44

15.84

1.6

2.4

1.41

1.11

e9/l

2.26

267

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

191

1006

1.91

15.77

2.1

2.4

1.28

1.20

e9/l

0.51

101

581

Other symptoms and signs involving the circulatory and respiratory systems

167

3.40

15.75

1.9

2.6

1.20

1.14

e9/l

0.17

Iridocyclitis in diseases classified elsewhere

6.21

15.70

1.8

1.9

1.14

1.16

e9/l

0.03

Ulcerative colitis

182

946

1.94

15.66

1.9

2.5

1.21

1.16

e9/l

0.21

557

Carcinoma in situ of skin of other and unspecified parts of face

4.78

15.65

1.9

2.0

1.12

1.00

e9/l

0.31

Diaphragmatic hernia

217

1195

1.83

15.58

2.4

2.3

1.11

1.15

e9/l

0.20

123

727

Other general symptoms and signs

115

3.93

15.58

2.1

1.53

1.42

e9/l

0.26

Sequelae of external causes of morbidity and mortality

171

872

1.98

15.57

2.5

2.4

1.18

1.14

e9/l

0.23

111

528

Hypermobility syndrome

154

3.50

15.54

1.9

2.9

1.56

1.29

e9/l

0.68

Misadventures to patients during surgical and medical care

102

424

2.43

15.53

2.4

2.2

1.06

1.09

e9/l

0.11

257

Intracranial trauma

344

1587

1.63

15.52

2.3

1.24

1.17

e9/l

0.66

209

989

Secondary right heart disease

4.64

15.45

2.7

2.0

1.38

1.06

e9/l

0.70

Gastric ulcer

110

474

2.34

15.42

1.9

2.3

0.90

1.06

e9/l

1.25

308

Temporomandibular joint disorders, including avohilmo

289

1729

1.68

15.42

2.0

2.4

1.36

1.20

e9/l

1.59

178

1016

IBD patients in KELA-register

175

904

1.95

15.36

1.8

2.5

1.14

1.19

e9/l

0.17

526

Diverticular disease of intestine

409

1748

1.56

15.21

2.1

2.4

1.14

1.10

e9/l

0.26

249

1082

Optic atrophy

5.81

15.20

5.4

2.5

1.62

1.22

e9/l

0.78

Atopic dermatitis, strict definition with reimbursement

229

1251

1.79

15.19

2.6

2.7

1.33

1.27

e9/l

0.46

152

761

Chronic gastritis

163

825

1.99

15.15

2.4

2.2

1.20

1.12

e9/l

0.39

527

Cystitis

543

2263

1.47

15.14

2.7

2.3

1.30

1.18

e9/l

1.59

315

1369

Polyarthrosis

116

493

2.27

15.11

2.1

2.3

1.12

1.10

e9/l

0.11

305

Pneumothorax

172

3.30

15.05

2.4

2.2

1.05

1.14

e9/l

0.34

Disorders of choroid and retina

484

2366

1.49

15.04

2.1

2.4

1.06

1.13

e9/l

1.02

278

1422

Other pulmonary heart/vessel disease

4.16

14.94

2.6

2.1

1.27

1.05

e9/l

0.52

Malignant neoplasm of respiratory system and intrathoracic organs

125

527

2.20

14.93

2.1

2.0

0.88

1.12

e9/l

2.74

325

Benign neoplasm: Rectum, anus and anal canal

330

2.59

14.92

1.8

2.1

1.16

1.03

e9/l

0.51

182

Benign neoplasm: Stomach

163

3.35

14.89

1.8

2.0

1.22

1.07

e9/l

0.54

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

164

3.38

14.86

2.7

2.9

1.58

1.42

e9/l

0.40

Other embolism and thrombosis

385

2.47

14.80

2.2

2.4

1.01

1.08

e9/l

0.34

239

Ulcerative enterocolitis

4.59

14.77

1.9

2.3

0.93

1.17

e9/l

0.41

Acute laryngitis and tracheitis

409

2.40

14.73

3.0

2.5

1.31

1.28

e9/l

0.09

228

Chronic hepatitis, not elsewhere classified

4.35

14.61

1.4

2.0

1.41

1.24

e9/l

0.38

Atopic dermatitis

377

2072

1.56

14.60

2.5

1.38

1.24

e9/l

1.55

214

1248

Other and unspecified acquired haemolytic anaemias

8.14

14.58

3.5

1.8

1.10

0.80

e9/l

—

Sequelae with surgical and medical care as external cause

137

662

2.09

14.53

2.6

2.3

1.12

1.13

e9/l

0.04

395

Anxiety (asthma-related co-morbidities)

413

2137

1.53

14.52

2.5

2.4

1.37

1.17

e9/l

3.46

244

1290

Viral hepatitis, IBD co-morbidity

100

4.05

14.52

3.5

2.6

1.41

1.06

e9/l

0.89

Chronic laryngitis and laryngotracheitis

100

426

2.37

14.45

1.8

2.5

1.44

1.05

e9/l

1.94

269

Benign neoplasm: Small intestine

5.27

14.41

2.1

1.13

1.16

e9/l

0.04

Depression or dysthymia

485

1822

1.49

14.38

2.7

2.3

1.26

1.10

e9/l

2.30

271

1091

Other abnormalities of plasma proteins

6.41

14.32

2.4

1.7

0.74

1.17

e9/l

1.05

TMD related pain

4.11

14.32

1.7

2.7

1.57

1.28

e9/l

0.41

Hypopituitarism

275

2.74

14.28

2.7

3.0

1.31

1.18

e9/l

0.51

169

Other ulcerative colitis

173

3.23

14.26

1.7

2.5

1.22

1.23

e9/l

0.02

Personal history of malignant neoplasm

4.24

14.19

2.3

1.53

1.12

e9/l

1.97

Polymyalgia rheumatica

293

2.65

14.13

2.1

2.0

1.05

1.04

e9/l

0.02

186

Recurrent or chronic depression

280

1214

1.67

14.11

2.5

2.4

1.37

1.16

e9/l

2.28

158

716

Dermatophytosis

394

2.41

14.11

2.4

1.07

1.15

e9/l

0.45

230

Pyothorax

107

3.91

14.10

1.7

2.2

1.04

0.99

e9/l

0.15

Congenital malformations of the respiratory system

4.39

14.06

2.2

3.8

1.62

1.41

e9/l

0.35

Other inflammation of eyelid

401

2.39

14.04

2.5

2.4

1.17

1.11

e9/l

0.28

247

Other arrhythmias

396

1987

1.53

13.96

2.1

2.6

1.14

1.18

e9/l

0.31

253

1153

Other/unspecified dorsalgia

238

1385

1.72

13.93

2.5

2.4

1.31

1.15

e9/l

0.91

140

844

Other headache syndromes

268

1619

1.66

13.91

2.2

2.5

1.40

1.15

e9/l

2.87

153

973

Clear cell adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

4.77

13.80

1.9

2.0

1.06

1.02

e9/l

0.07

Voice disturbances

178

960

1.87

13.76

1.9

2.4

1.23

1.16

e9/l

0.34

124

564

Malignant neoplasm of skin

329

1563

1.59

13.68

2.1

2.2

1.15

1.08

e9/l

0.58

204

948

Early onset COPD

149

760

1.98

13.63

1.7

2.5

1.19

1.13

e9/l

0.27

464

Papilloedema, unspecified

4.77

13.62

3.0

2.4

1.14

1.51

e9/l

0.83

Crohn's disease of small intestine

215

2.93

13.61

1.8

2.7

1.10

1.20

e9/l

0.28

123

Other anxiety disorders

303

1676

1.61

13.60

2.2

2.5

1.42

1.20

e9/l

3.43

183

986

Paralytic ileus and intestinal obstruction

150

767

1.97

13.59

2.1

2.4

1.12

1.14

e9/l

0.09

493

Inflammatory bowel disease, strict (require KELA)

175

943

1.87

13.58

1.8

2.6

1.14

1.21

e9/l

0.27

550

Endocarditis

4.59

13.58

1.9

2.9

1.11

1.06

e9/l

0.09

Crohn's disease of large intestine

158

3.28

13.57

1.8

2.7

1.01

1.21

e9/l

0.65

Other disorders of bone

144

727

2.00

13.57

2.8

2.6

1.39

1.16

e9/l

1.84

419

Seborrhoeic dermatitis

271

2.69

13.54

2.7

2.5

1.19

1.13

e9/l

0.20

169

Speech and linguistic disorders, excluding more controls

304

2.54

13.43

4.3

2.6

1.45

1.33

e9/l

0.30

174

Concussion

286

1525

1.63

13.43

2.4

2.2

1.26

1.17

e9/l

0.78

175

956

Other intervertebral disc disorders

521

2210

1.45

13.43

2.3

2.4

1.25

1.13

e9/l

1.77

294

1318

Biological medicines for asthma

6.54

13.39

1.2

2.0

1.58

1.26

e9/l

0.69

Vascular disorders of the intestines

125

3.56

13.35

1.5

2.0

0.93

1.04

e9/l

0.25

Diseases of arteries, arterioles and capillaries

380

1859

1.53

13.35

2.0

2.4

1.01

1.12

e9/l

0.94

232

1131

Osteomyelitis

175

3.13

13.34

1.9

2.2

1.14

1.02

e9/l

0.31

Pulmonary eosinophilia, not elsewhere classified

8.81

13.33

2.5

1.6

1.33

1.04

e9/l

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

131

644

2.05

13.30

1.9

2.1

1.15

1.09

e9/l

0.21

394

Tonsillectomy and adenotomy

425

1985

1.50

13.29

2.6

1.46

1.23

e9/l

4.25

246

1186

Other obstetric conditions, not elsewhere classified

228

852

1.75

13.18

2.0

2.5

1.39

1.35

e9/l

0.26

143

469

Keratitis

229

1349

1.71

13.12

2.5

1.18

1.20

e9/l

0.13

142

813

Disorders of gallbladder, biliary tract and pancreas

612

2833

1.40

13.04

2.5

2.4

1.14

1.15

e9/l

0.11

374

1686

Juvenile arthritis (FINNGEN)

157

3.24

13.04

2.0

3.8

1.21

1.30

e9/l

0.23

Gastroduodenal ulcer

144

736

1.96

13.00

1.8

2.3

0.89

1.11

e9/l

2.62

472

Benign neoplasm of eye and adnexa

183

3.03

12.97

2.6

2.1

1.43

1.12

e9/l

0.48

108

Malignant neoplasm of adrenal gland, excluding all cancers (controls excluding all cancers)

11.34

12.96

4.6

3.4

1.50

0.89

e9/l

—

Ulcer of lower limb, not elsewhere classified

354

2.42

12.96

1.8

2.2

1.06

1.05

e9/l

0.05

216

Other diseases of blood and blood-forming organs

168

3.14

12.92

2.0

2.1

1.23

1.11

e9/l

0.31

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

4.28

12.91

1.6

2.0

0.81

1.00

e9/l

0.62

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

222

828

1.75

12.90

2.0

2.5

1.37

1.34

e9/l

0.15

137

456

Gout, unspecified

117

559

2.11

12.84

2.5

2.2

1.01

1.10

e9/l

0.40

344

Chronic nephritic syndrome

3.93

12.84

1.9

2.6

0.99

1.15

e9/l

0.53

Osteonecrosis due to drugs

7.34

12.81

4.4

2.2

0.88

0.96

e9/l

0.11

Psoriasis

187

1048

1.80

12.80

2.3

2.5

1.13

1.18

e9/l

0.30

129

616

Other or unspecified ileus, impaction or obstruction

108

501

2.17

12.76

1.8

2.4

1.10

1.12

e9/l

0.09

321

Correction of physiology of bite - demanding therapy visit

223

2.82

12.76

2.0

2.4

1.23

1.22

e9/l

0.03

139

Opening and dilatation of root channel of tooth

196

2.95

12.73

2.5

2.6

1.09

1.23

e9/l

0.51

111

Migraine without aura

144

744

1.95

12.73

2.0

2.7

1.42

1.17

e9/l

1.75

442

Fitting and adjustment of other devices

175

892

1.83

12.72

2.1

2.4

1.05

1.12

e9/l

0.38

535

Hyperkalaemia

115

3.62

12.72

1.8

2.2

0.82

1.02

e9/l

0.97

Fissure and fistula of anal and rectal regions

158

842

1.89

12.71

2.3

2.4

1.18

1.19

e9/l

0.04

519

Cerebral palsy and other paralytic syndromes

389

2.34

12.66

2.8

2.6

1.33

1.22

e9/l

0.34

230

Myeloproliferative diseases (CML excluded)

202

2.91

12.66

3.7

2.1

0.77

1.07

e9/l

1.32

119

Other inflammatory liver diseases

186

3.00

12.65

2.6

2.4

1.10

1.12

e9/l

0.03

113

Exposure to unspecified factor

631

3572

1.37

12.64

2.2

2.5

1.21

1.18

e9/l

0.37

388

2137

Sleep disorders (combined)

630

2999

1.38

12.63

2.1

2.5

1.28

1.14

e9/l

2.32

374

1780

Dental caries, including avohilmo

511

1815

1.44

12.57

2.5

2.3

1.26

1.15

e9/l

1.25

319

1077

Faecal incontinence

192

2.95

12.55

2.6

2.2

1.20

1.00

e9/l

0.92

120

Disorders of refraction and accommodation

200

1146

1.75

12.53

3.0

2.6

1.36

1.24

e9/l

0.91

135

682

Melanocytic naevi, other sites/unspecified

166

3.11

12.51

2.5

1.05

1.21

e9/l

0.82

Benzodiazepine use

631

3275

1.37

12.50

2.4

1.24

1.15

e9/l

1.37

349

1968

Benign neoplasm: Skin of trunk

4.28

12.48

2.1

1.8

0.94

1.21

e9/l

0.90

Bronchitis, not specified as acute or chronic

260

2.64

12.43

2.6

2.5

1.28

1.12

e9/l

0.58

143

Spondylopathies (FG)

443

2.23

12.39

1.7

2.7

1.15

1.20

e9/l

0.20

252

Dental caries 1

510

1817

1.44

12.34

2.5

2.3

1.26

1.15

e9/l

1.25

319

1077

Unknown and unspecified causes of morbidity

142

3.27

12.30

2.6

2.3

1.53

1.18

e9/l

1.24

Other diseases of the digestive system

179

1002

1.80

12.30

2.3

2.4

0.98

1.13

e9/l

1.28

104

619

Unspecified nephritic syndrome

5.23

12.27

2.2

0.93

1.14

e9/l

0.47

COPD, hospital admissions

246

1264

1.65

12.27

1.7

2.3

1.13

1.07

e9/l

0.35

143

778

Other endocrine disorders

280

2.56

12.25

4.3

2.9

1.52

1.42

e9/l

0.28

174

Other cataract

244

1141

1.66

12.24

2.6

2.3

1.08

1.09

e9/l

0.07

141

690

Other noninfective disorders of lymphatic vessels and lymph nodes

3.92

12.13

2.3

1.9

0.84

1.10

e9/l

1.10

Special screening examination for other diseases and disorders

191

2.90

12.05

2.2

2.0

1.28

1.11

e9/l

0.66

131

TMD related operations

124

621

2.01

12.03

1.8

2.4

1.17

1.23

e9/l

0.26

374

Psoriasis vulgaris

129

656

1.98

11.98

2.4

1.11

1.19

e9/l

0.38

377

Drug-induced polyneuropathy

6.21

11.97

6.7

3.2

1.16

1.17

e9/l

0.01

L04AC Interleukin inhibitors

150

3.19

11.96

1.7

2.8

1.26

1.20

e9/l

0.15

COPD, early/later onset

247

1276

1.64

11.96

1.7

2.3

1.13

1.08

e9/l

0.35

144

786

Carcinoma in situ of skin of trunk

6.66

11.95

2.3

2.4

1.16

0.81

e9/l

0.84

Symptoms and signs involving cognition, perception, emotional state and behaviour

604

3089

1.37

11.93

2.3

2.4

1.25

1.15

e9/l

1.51

344

1859

COPD-related respiratory insufficiency

295

2.50

11.92

1.7

2.0

1.31

1.05

e9/l

0.98

175

Other peripheral vascular diseases

220

2.76

11.92

1.8

2.4

0.85

1.19

e9/l

2.57

145

Intestinal stricture

181

1027

1.77

11.91

2.1

2.4

1.08

1.17

e9/l

0.63

120

638

Gout, idiopatic and unspecified

137

713

1.93

11.88

2.5

2.2

1.05

1.06

e9/l

0.06

439

Visual field defects

226

2.73

11.88

2.0

2.4

1.19

1.08

e9/l

0.45

140

Filling of root of tooth

3.95

11.88

2.9

2.3

1.08

1.20

e9/l

0.31

Varicella [chickenpox]

177

2.99

11.88

2.4

2.8

1.23

1.17

e9/l

0.14

Other juvenile arthritis

151

3.17

11.85

2.0

3.8

1.24

1.26

e9/l

0.04

101

Other specified congenital malformation syndromes affecting multiple systems

3.84

11.82

4.4

4.1

1.34

1.31

e9/l

0.05

Fibromyalgia

273

2.56

11.80

1.8

2.6

1.36

1.16

e9/l

1.10

171

Atrial fibrillation and flutter with reimbursement

155

525

1.90

11.79

2.4

2.8

0.97

1.06

e9/l

0.61

109

290

GI-bleeding

178

1008

1.77

11.78

2.3

2.4

0.98

1.12

e9/l

1.28

105

618

Invasive ventilation

233

2.70

11.77

2.3

2.4

1.39

1.20

e9/l

0.59

140

Retention of urine

188

909

1.76

11.71

2.2

2.3

1.14

1.05

e9/l

0.63

114

573

Infections with a predominantly sexual mode of transmission

210

1249

1.69

11.65

2.6

2.4

1.27

1.24

e9/l

0.12

104

735

Deforming dorsopathies

180

1028

1.76

11.60

1.9

2.5

1.11

1.17

e9/l

0.34

113

633

Dental caries 3

545

1989

1.40

11.59

2.4

2.3

1.25

1.16

e9/l

1.03

329

1189

Convalescence

113

3.50

11.55

1.8

2.6

0.98

1.17

e9/l

0.69

Nephrotic syndrome

109

3.57

11.48

2.4

3.0

1.31

1.29

e9/l

0.04

Benign neoplasm: Other and unspecified parts of small intestine

7.82

11.47

1.9

1.7

1.25

0.92

e9/l

—

Golimumab

3.76

11.44

1.5

3.1

1.09

1.23

e9/l

0.26

Guillain-Barre syndrome

5.54

11.43

3.0

2.0

1.21

e9/l

0.00

Impetigo

165

3.03

11.42

2.7

2.6

1.44

1.31

e9/l

0.29

102

Allergic rhinitis

231

1403

1.64

11.42

2.1

2.7

1.44

1.23

e9/l

2.64

142

842

Conduction disorders

162

742

1.82

11.41

2.1

2.5

1.01

1.16

e9/l

1.22

452

Bell's palsy

382

2.27

11.40

2.7

2.5

1.26

1.15

e9/l

0.44

237

Exclusion endpoint for clefts

120

3.46

11.36

4.0

3.8

1.35

1.34

e9/l

0.03

Carcinoma in situ of skin

100

3.63

11.33

2.0

0.95

1.03

e9/l

0.24

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

149

3.10

11.32

2.3

1.9

1.19

0.99

e9/l

0.48

Disorders of psychological development

114

523

2.04

11.32

3.6

2.8

1.39

1.35

e9/l

0.10

314

Scleritis

6.35

11.28

2.4

2.0

0.62

1.17

e9/l

—

Other and unspecified haemorrhagic conditions

5.70

11.24

3.5

2.1

0.91

1.07

e9/l

0.27

Atlantoaxial subluxation

9.23

11.23

1.7

1.6

0.97

1.07

e9/l

—

Phlebitis and thrombophlebitis (not including DVT)

139

742

1.89

11.20

2.1

2.4

1.02

1.18

e9/l

1.21

452

Allergic purpura

3.93

11.15

2.0

2.5

0.94

1.26

e9/l

0.91

Scleritis and episcleritis

178

2.91

11.14

2.4

2.5

1.12

1.15

e9/l

0.07

108

Inflammatory diseases of female pelvic organs

361

1838

1.49

11.12

2.1

2.3

1.38

1.20

e9/l

2.25

197

1105

Malignant neoplasm of heart, mediastinum and pleura

5.95

11.11

2.4

1.7

1.03

1.13

e9/l

0.14

Sciatica+with lumbago

299

1861

1.53

11.02

2.3

2.4

1.30

1.12

e9/l

2.65

194

1110

Benign neoplasm of major salivary glands

168

2.94

11.02

2.0

1.07

1.08

e9/l

0.04

Preparatory care for dialysis

112

3.46

11.01

2.0

2.1

1.05

1.07

e9/l

—

Benign neoplasm of other and ill-defined parts of digestive system

112

560

2.02

10.96

2.1

2.3

1.19

1.10

e9/l

0.47

336

Other diseases of intestine

338

2.33

10.96

2.7

2.4

1.12

1.09

e9/l

0.08

208

Postmenopausal osteoporosis with pathological fracture

103

3.54

10.88

2.6

1.4

1.00

0.98

e9/l

0.03

Sleep apnoea

559

2774

1.37

10.87

2.1

2.5

1.26

1.11

e9/l

2.22

326

1651

Excessive attrition of teeth

258

870

1.62

10.87

2.3

2.5

1.23

1.16

e9/l

0.41

154

524

Intestinal malabsorption

123

3.31

10.84

3.0

2.6

1.08

1.20

e9/l

0.30

Pruritus

309

2.38

10.83

2.3

2.2

1.27

1.13

e9/l

0.64

198

Other disorders of conjunctiva

430

2.16

10.78

2.3

1.27

1.07

e9/l

1.13

265

CR(E)ST syndrome

5.73

10.77

2.1

1.8

0.99

1.22

e9/l

0.38

Pyogenic arthritis

176

2.87

10.75

1.8

2.5

1.04

1.15

e9/l

0.36

104

Malignant neoplasm, without specification of site

4.78

10.74

3.1

2.0

0.96

0.88

e9/l

0.18

Explicit fungal Sepsis

8.73

10.73

1.6

2.3

1.41

1.03

e9/l

—

Algoneurodystrophy

4.10

10.71

1.8

2.3

1.89

1.11

e9/l

2.29

Erythema nodosum

4.20

10.65

2.3

2.0

1.39

1.13

e9/l

0.55

Other and unspecified myoneural disorders

10.89

10.60

2.3

2.2

1.36

0.90

e9/l

—

Congenital malformations of trachea and bronchus

5.70

10.54

1.9

3.7

1.74

1.38

e9/l

0.38

Erosion of teeth, including avohilmo

134

696

1.87

10.53

2.6

2.5

1.22

1.15

e9/l

0.28

421

Deviated nasal septum

202

1223

1.66

10.52

2.0

2.5

1.22

1.07

e9/l

1.49

113

745

Malignant neoplasm of oral cavity, excluding all cancers (controls excluding all cancers)

4.11

10.43

2.0

2.1

0.70

1.08

e9/l

1.70

Other chronic obstructive pulmonary disease, including avohilmo

288

1572

1.53

10.40

1.7

2.3

1.13

1.09

e9/l

0.33

167

960

Other dialysis

102

3.51

10.36

2.1

2.4

1.19

1.14

e9/l

0.07

Malignant neoplasm of bone and articular cartilage

5.89

10.35

2.4

2.7

1.04

1.29

e9/l

0.39

Malignant neoplasm of eye and adnexa, excluding all cancers (controls excluding all cancers)

6.46

10.32

2.4

1.6

1.18

0.86

e9/l

—

Type 2 diabetes, wide definition

475

2227

1.39

10.21

2.1

2.5

1.15

1.12

e9/l

0.21

322

1291

Juvenile rheumatoid arthirtis

4.29

10.15

2.4

2.8

0.85

1.31

e9/l

1.73

Vulvovaginal ulceration/inflammation in other diseases

182

2.78

10.14

2.6

2.4

1.60

1.27

e9/l

0.96

111

Adult respiratory distress syndrome

6.01

10.14

1.8

1.7

1.02

0.97

e9/l

0.06

Dependence on enabling machines and devices, not elsewhere classified

4.97

10.06

2.7

2.1

1.46

1.72

e9/l

0.27

Other congenital malformations

390

2.18

10.06

3.9

2.9

1.31

1.33

e9/l

0.05

233

Other follicular disorders

229

2.56

10.03

2.5

2.8

1.20

1.25

e9/l

0.15

131

Thyroiditis, ILD-related definition

320

2.30

10.02

2.0

2.2

1.17

1.29

e9/l

0.50

196

Chronic myeloid leukaemia [CML], BCR/ABL-positive

6.69

9.90

4.4

2.0

0.88

1.16

e9/l

—

Unspecified chronic bronchitis

3.76

9.89

1.8

2.0

1.25

1.07

e9/l

0.38

Melanocytic naevi

186

1123

1.67

9.87

2.4

2.5

1.12

1.19

e9/l

0.45

117

653

Benign neoplasm: Ascending colon

213

2.60

9.86

2.8

2.0

0.99

1.01

e9/l

0.05

125

Diseases of inner ear

293

1923

1.50

9.82

2.2

2.3

1.12

1.13

e9/l

0.11

172

1149

Giant cell arteritis

3.57

9.80

2.4

1.8

1.35

0.98

e9/l

1.06

Folate deficiency anaemia

7.69

9.78

3.7

1.8

1.03

0.67

e9/l

—

External causes of morbidity and mortality

476

1715

1.39

9.77

2.5

2.4

1.25

1.19

e9/l

0.45

290

1044

Non-selective monoamine reuptake inhibitors

225

1383

1.58

9.75

1.8

2.3

1.37

1.14

e9/l

1.96

132

844

Reactive arthropathies, FINNGEN

209

2.61

9.73

2.1

2.9

1.21

1.18

e9/l

0.09

118

Abnormalities of gait and mobility

350

2.22

9.72

2.7

2.3

1.30

1.19

e9/l

0.45

215

Allergic urticaria

281

2.37

9.72

2.5

2.9

1.45

1.24

e9/l

0.60

183

Hernia

573

2908

1.34

9.71

2.5

2.4

1.18

1.16

e9/l

0.22

353

1731

Migraine with aura

154

888

1.74

9.69

2.0

2.5

1.37

1.16

e9/l

1.57

518

Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)

5.39

9.68

1.8

1.29

0.88

e9/l

0.60

Malignant neoplasm of tonsil, excluding all cancers (controls excluding all cancers)

6.01

9.64

1.9

1.8

1.36

0.86

e9/l

0.72

Benign neoplasm: Caecum

170

2.79

9.64

2.6

1.9

0.93

1.01

e9/l

0.22

Temporal arteritis

3.78

9.63

2.2

1.8

1.35

0.99

e9/l

1.02

Benign neoplasm of colon, rectum, anus and anal canal

324

2004

1.46

9.62

2.3

1.07

1.10

e9/l

0.21

175

1235

Cardiomyopathy

100

504

2.00

9.62

2.2

2.4

1.05

1.12

e9/l

0.27

300

Benign neoplasm: Colon

271

1760

1.51

9.59

2.3

1.06

1.09

e9/l

0.16

142

1089

Diseases of tongue

138

3.00

9.58

1.8

1.9

1.13

1.02

e9/l

0.36

Unspecified haematuria

231

1263

1.57

9.55

2.5

2.3

1.09

1.12

e9/l

0.25

133

795

Anomalies of dental arch relationship, including avohilmo

148

758

1.77

9.54

2.9

2.5

1.31

1.28

e9/l

0.15

101

458

Dizziness and giddiness

436

2555

1.39

9.54

2.3

2.4

1.28

1.13

e9/l

2.05

236

1523

Ehlers-Danlos syndrome

6.39

9.54

1.1

2.8

1.57

1.30

e9/l

—

Disorders of synovium and tendon

318

1960

1.47

9.52

2.5

2.4

1.25

1.12

e9/l

1.01

175

1179

Irregular menses

288

1563

1.50

9.52

2.7

2.2

1.31

1.23

e9/l

0.80

172

940

Benign neoplasm: Sigmoid colon

302

2.30

9.51

2.1

2.0

1.19

1.01

e9/l

0.73

168

Atopic dermatitis, strict definition

221

1377

1.58

9.50

2.6

1.36

1.28

e9/l

0.63

145

830

Other CVD

100

507

1.98

9.46

1.7

2.2

1.09

e9/l

0.00

321

Benign neoplasm: Parotid gland

139

2.98

9.46

2.0

2.1

1.12

1.13

e9/l

0.02

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

135

730

1.80

9.45

2.3

2.8

1.17

1.28

e9/l

0.49

449

Dental pulpitis 2

441

1614

1.40

9.44

2.5

2.2

1.25

1.16

e9/l

0.87

285

952

Malignant neoplasm of bone and articular cartilage of other and unspecified sites

7.56

9.44

2.1

2.3

1.05

1.27

e9/l

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

191

1175

1.63

9.44

2.1

2.5

1.28

1.23

e9/l

0.32

101

688

Other and unspecified visual disturbances

273

2.37

9.40

2.5

2.3

1.07

1.13

e9/l

0.21

170

Polyarteritis nodosa

7.36

9.38

1.9

2.0

1.24

0.85

e9/l

—

Psoriatic and enteropathic arthropathies

349

2.20

9.37

1.6

2.8

1.14

1.16

e9/l

0.05

197

Speech and linguistic disorders

417

2.07

9.34

4.2

2.8

1.52

1.35

e9/l

0.51

255

Focal epilepsy

144

824

1.76

9.33

2.5

2.7

1.04

1.21

e9/l

1.55

507

Other/unspecified reactive arthropathies

202

2.61

9.33

2.1

2.6

1.22

1.14

e9/l

0.29

117

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

292

2.30

9.33

2.2

1.9

1.22

1.02

e9/l

0.32

169

Giant cell arteritis with polymyalgia rheumatica

3.69

9.30

2.2

1.8

1.35

1.03

e9/l

0.86

Benign neoplasm of mouth and pharynx

202

2.59

9.29

2.4

2.1

0.96

1.10

e9/l

0.68

110

Cholangitis (primary sclerosing, PSC)

163

2.79

9.24

1.7

2.6

0.97

1.14

e9/l

0.59

Asthma mixed form (mode)

3.40

9.17

1.6

2.3

1.10

1.15

e9/l

0.12

Paraplegia, diplegia of upper limbs

4.36

9.17

4.0

2.0

1.16

1.06

e9/l

0.18

Heart failure and bmi 25plus

188

788

1.65

9.15

2.4

2.3

0.88

1.16

e9/l

4.47

111

473

Other retinal disorders

334

1863

1.44

9.14

2.0

2.4

1.04

1.13

e9/l

0.91

199

1128

Other abnormal immunological findings in serum

4.51

9.13

2.0

2.6

1.65

1.20

e9/l

0.76

Benign neoplasm: Transverse colon

164

2.77

9.12

2.2

1.8

0.92

1.00

e9/l

0.31

Herpesviral keratitis and keratoconjunctivitis

101

3.31

9.05

2.9

2.1

1.19

1.10

e9/l

0.27

Otitis externa, unspecified

374

2.13

9.05

2.8

2.7

1.23

1.18

e9/l

0.17

219

Other disorders of central nervous system

5.67

9.04

3.5

2.2

1.43

1.14

e9/l

0.33

Asthma mixed form (mode), excluding more controls

3.36

9.03

1.6

2.3

1.10

1.14

e9/l

0.07

Conductive and sensorineural hearing loss

449

2270

1.37

9.00

2.3

2.5

1.11

e9/l

0.02

271

1378

Clefts and syndromes for tooth agenesis exclusion, including avohilmo

183

2.68

8.98

3.6

3.4

1.41

1.39

e9/l

0.04

115

Congenital malformations and deformations of the musculoskeletal system

447

2.03

8.97

2.2

2.9

1.48

1.36

e9/l

0.52

271

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

122

399

1.87

8.93

2.5

2.2

0.99

e9/l

0.00

213

Need for other prophylactic measures

172

2.71

8.92

3.8

2.8

1.29

1.19

e9/l

0.27

107

Myelodysplastic syndrome

7.51

8.91

9.3

1.8

0.73

0.94

e9/l

—

Lupus erythematosus

4.40

8.90

1.8

2.0

0.56

1.08

e9/l

3.54

Neuralgia and neuritis, unspecified

150

2.84

8.87

1.8

2.5

1.38

1.18

e9/l

0.49

Benign lipomatous neoplasm

115

625

1.85

8.85

1.7

2.1

1.21

1.17

e9/l

0.17

348

Migraine with aura and triptan purchases

106

562

1.90

8.84

2.0

2.6

1.36

1.22

e9/l

0.77

311

Polycythaemia vera

4.71

8.84

4.0

2.3

0.72

1.09

e9/l

—

Rosacea

378

2.11

8.81

2.3

2.2

1.18

e9/l

0.00

228

Crohn disease (strict definition, require KELA)

214

2.51

8.80

1.8

2.8

0.94

1.24

e9/l

1.42

124

Crossbite

331

2.16

8.80

3.3

3.2

1.40

1.24

e9/l

0.56

216

Cerebral cysts

168

2.71

8.75

2.3

2.6

1.44

1.21

e9/l

0.65

Myositis

3.92

8.73

1.6

2.3

0.92

1.09

e9/l

0.43

Episcleritis

146

2.85

8.71

2.6

2.4

1.21

1.17

e9/l

0.08

Autonomic disorders

4.32

8.70

2.9

2.0

1.33

1.24

e9/l

0.15

Focal epilepsy, strict definition

132

753

1.76

8.69

2.5

2.6

1.03

1.21

e9/l

1.55

469

Disorders of eyelid in diseases classified elsewhere

3.51

8.68

2.5

2.1

0.97

1.04

e9/l

0.17

Gout, strict definition

517

1.93

8.65

2.4

2.2

1.06

1.09

e9/l

0.09

319

Basal cell carcinoma

269

1443

1.49

8.64

2.0

2.2

1.12

1.07

e9/l

0.39

155

884

Pain associated with micturition

368

2.11

8.62

3.3

2.3

1.23

1.19

e9/l

0.15

237

Ascites

175

2.66

8.62

2.1

2.2

0.94

1.03

e9/l

0.26

105

Persons encountering health services in circumstances related to reproduction

387

1882

1.40

8.61

2.7

1.41

1.18

e9/l

3.45

249

1138

Disorders of vestibular function (Vertigo)

245

1621

1.51

8.57

2.2

2.3

1.14

e9/l

0.02

143

978

Unspecified misadventure during surgical and medical care

142

2.85

8.56

2.0

2.4

1.10

1.07

e9/l

0.07

Carcinoma in situ of skin of upper limb, including shoulder

6.47

8.55

1.7

1.8

1.06

0.82

e9/l

—

Felty syndrome

8.90

8.54

1.9

2.0

0.40

0.99

e9/l

—

Other diseases of liver

113

619

1.84

8.53

2.5

1.20

1.17

e9/l

0.10

370

Adverse effects, not elsewhere classified

138

802

1.73

8.53

2.1

2.6

1.40

1.20

e9/l

1.48

475

Other disorders of eyelid

219

1378

1.54

8.48

2.1

2.2

1.17

1.08

e9/l

0.35

118

835

Lumbar disc prolapse

369

2103

1.40

8.45

2.3

2.4

1.32

1.12

e9/l

2.70

212

1257

Parapsoriasis

4.39

8.45

1.6

2.4

1.60

1.24

e9/l

0.46

Strabismus

185

1161

1.60

8.43

3.0

2.6

1.26

1.25

e9/l

0.05

123

699

Oesophageal varices

106

3.16

8.40

1.4

2.6

0.55

1.09

e9/l

3.97

Cholelithiasis, broad definition with cholecystitis

493

2530

1.34

8.40

2.3

2.4

1.14

1.15

e9/l

0.13

304

1503

Malignant cancer of tonsil and base of tongue, excluding all cancers (controls excluding all cancers)

4.53

8.40

1.8

2.3

1.31

0.93

e9/l

0.55

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

149

2.78

8.38

2.6

2.1

1.09

1.17

e9/l

0.22

Malignant melanoma, excluding all cancers (controls excluding all cancers)

287

2.24

8.38

2.5

2.0

1.11

1.06

e9/l

0.19

162

Other disorders of kidney and ureter

400

2.04

8.33

2.4

2.3

1.14

1.08

e9/l

0.19

236

Crohn disease (strict definition, require KELA, min 2 HDR)

214

2.46

8.32

1.8

2.8

0.94

1.24

e9/l

1.42

124

Paralytic strabismus

202

2.50

8.31

2.9

2.3

1.24

1.12

e9/l

0.46

124

Paroxysmal tachycardia

134

653

1.74

8.29

1.9

3.1

1.08

1.19

e9/l

0.79

366

Migraine without aura and triptan purchases

111

611

1.83

8.26

1.7

2.5

1.42

1.24

e9/l

0.92

344

Colorectal cancer, excluding all cancers (controls excluding all cancers)

446

1.96

8.26

2.0

1.13

1.03

e9/l

0.23

248

Diseases of pulp and periapical tissues, including avohilmo

692

2808

1.28

8.26

2.4

1.24

1.16

e9/l

0.98

437

1656

Post-traumatic stress disorder

258

2.31

8.23

2.4

1.52

1.21

e9/l

1.55

155

Status epilepticus

3.38

8.23

2.3

2.5

1.10

1.20

e9/l

0.18

Malignant neoplasm of head and neck

215

2.44

8.22

2.0

2.3

1.00

1.03

e9/l

0.06

123

Dental pulpitis 4

693

2815

1.28

8.20

2.4

1.24

1.16

e9/l

1.00

437

1666

Triptan medication for migraine, min. 3 purchases

344

1935

1.41

8.18

2.0

2.5

1.36

1.21

e9/l

2.00

203

1143

Dental caries 2

490

2902

1.33

8.18

2.8

2.4

1.24

1.21

e9/l

0.28

255

1770

Migraine, single triptan purchase ok & required. ICD-code if available is included

485

2463

1.34

8.17

2.3

2.5

1.34

1.17

e9/l

2.97

279

1452

Triptan medication for migraine, single purchase ok

485

2463

1.34

8.17

2.3

2.5

1.34

1.17

e9/l

2.97

279

1452

Motor disorders, excluding more controls

103

3.17

8.17

3.4

2.9

1.73

1.49

e9/l

0.35

In situ neoplasms

190

1211

1.58

8.17

2.2

2.3

1.17

1.16

e9/l

0.05

119

733

Other and unspecified vaccines and biological substances

6.82

8.15

2.6

1.5

0.82

1.49

e9/l

—

Dental pulpitis 1

693

2819

1.28

8.13

2.4

1.24

1.16

e9/l

1.02

436

1667

Hypotension

390

2.04

8.12

1.6

1.9

1.17

1.09

e9/l

0.26

243

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

229

2.38

8.10

1.8

2.8

0.94

1.23

e9/l

1.33

133

Nummular dermatitis

223

2.40

8.08

2.5

2.6

1.13

1.10

e9/l

0.07

140

Focal epilepsy, mode (most common among epilepsy diagnosis)

122

696

1.76

8.06

2.5

2.7

1.02

1.19

e9/l

1.54

427

Abnormal involuntary movements

427

1.98

7.98

2.6

2.4

1.53

1.17

e9/l

0.91

257

Benign neoplasm: Skin of eyelid, including canthus

274

2.24

7.98

2.2

1.26

1.09

e9/l

0.71

152

Amyloidosis, other/unspecified

5.28

7.97

1.3

2.1

1.12

0.91

e9/l

—

Malnutrition

3.79

7.96

3.2

2.7

1.39

1.07

e9/l

0.38

Diseases of external ear

202

1314

1.54

7.96

2.3

2.5

1.27

1.19

e9/l

0.54

115

812

Other salmonella infections

3.30

7.95

2.2

2.1

0.95

1.12

e9/l

0.50

Hypothyroidism, other/unspecified

532

2679

1.31

7.95

2.3

2.4

1.16

e9/l

0.00

317

1577

Emphysema

171

2.60

7.93

1.8

2.2

1.00

1.04

e9/l

0.10

Sensorineural hearing loss

411

2118

1.36

7.90

2.3

2.5

1.11

1.10

e9/l

0.03

240

1290

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

113

635

1.79

7.89

1.8

2.4

1.24

1.19

e9/l

0.16

383

Colonic or urogenital fistula

164

1019

1.62

7.88

2.3

2.4

1.19

1.17

e9/l

0.07

617

Other local infections of skin and subcutaneous tissue

328

2.12

7.88

3.5

2.7

1.07

1.13

e9/l

0.18

195

Basal cell carcinoma, including avohilmo

273

1480

1.46

7.87

2.0

2.2

1.12

1.06

e9/l

0.36

159

905

Excessive, frequent and irregular menstruation

247

916

1.51

7.86

2.6

2.2

1.25

1.22

e9/l

0.22

151

561

Delayed milestone in childhood

183

2.53

7.85

3.6

4.1

1.45

1.55

e9/l

0.20

128

Visual impairment including blindness (binocular or monocular)

172

2.58

7.84

2.5

2.3

1.18

1.16

e9/l

0.04

101

Other epidermal thickening

116

2.97

7.83

2.3

2.2

1.33

1.15

e9/l

0.49

Squamous cell neoplasms and carcinomas of the skin

270

2.24

7.83

2.0

1.9

1.18

0.98

e9/l

1.00

169

Haemorrhage, not elsewhere classified

4.09

7.81

3.8

1.5

0.95

1.20

e9/l

0.51

Polycystic ovarian syndrome, consortium definition

406

1797

1.37

7.78

2.5

2.2

1.31

1.21

e9/l

1.14

233

1077

Short Achilles tendon (acquired)

3.70

7.77

3.3

2.2

1.41

1.13

e9/l

0.21

Tuberculosis, IBD comorbidity

167

2.60

7.76

1.9

2.0

1.67

1.05

e9/l

0.85

100

Anogenital herpesviral [herpes simplex] infection

209

2.42

7.76

2.4

2.6

1.20

e9/l

0.00

122

Other disorders of nervous system

185

2.51

7.75

2.0

2.2

1.18

1.12

e9/l

0.17

113

Ulcerative colitis (strict definition, require KELA)

115

654

1.77

7.72

1.8

2.4

1.25

1.18

e9/l

0.21

393

Benign neoplasm of urinary organs

3.90

7.70

2.0

1.8

2.13

1.10

e9/l

0.61

Injury, poisoning and certain other consequences of external causes

389

1415

1.38

7.69

2.4

1.27

1.21

e9/l

0.43

239

857

Respiratory tuberculosis, confirmed

4.59

7.68

1.6

1.7

1.63

0.98

e9/l

—

Osteopathy in diseases classified elsewhere

6.97

7.68

2.1

2.3

0.87

1.04

e9/l

—

Acquired pure red cell aplasia [erythroblastopenia]

8.83

7.66

2.4

2.0

0.63

1.02

e9/l

—

Pacemaker

154

921

1.63

7.66

2.0

2.1

0.91

1.06

e9/l

1.42

106

565

Hyperlipidaemia, other/unspecified

191

1170

1.55

7.64

2.3

1.12

1.07

e9/l

0.23

123

698

Cramp and spasm

140

2.75

7.63

2.8

2.2

1.33

1.22

e9/l

0.34

Sleep apnoea, including avohilmo

570

2865

1.29

7.61

2.1

2.5

1.25

1.12

e9/l

1.79

336

1707

Disorders of myoneural junction and muscle in diseases classified elsewhere

7.60

7.61

2.6

1.9

0.77

0.94

e9/l

—

Renal tubulo-interstitial disorders in diseases classified elsewhere

5.80

7.60

2.0

2.3

1.04

0.89

e9/l

—

Otitis externa

140

845

1.67

7.57

2.5

2.6

1.23

1.19

e9/l

0.17

504

Acute nasopharyngitis (common cold)

351

2.05

7.56

2.3

2.6

1.28

1.20

e9/l

0.34

209

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

424

1.93

7.54

2.4

2.1

0.94

1.19

e9/l

2.52

227

Non-small cell lung cancer

422

1.95

7.54

1.7

2.0

0.87

1.10

e9/l

1.84

260

Perforation of tympanic membrane

314

2.12

7.54

2.3

2.5

1.23

1.11

e9/l

0.53

182

Lichen simplex chronicus and prurigo

158

2.62

7.53

2.1

2.0

1.15

1.10

e9/l

0.12

100

Cholelithiasis

468

2483

1.32

7.53

2.3

2.4

1.14

1.16

e9/l

0.11

288

1472

Tuberculosis

141

2.72

7.51

1.7

2.1

1.45

1.01

e9/l

0.51

Hyperparathyroidism

466

1.90

7.49

2.4

2.2

0.99

1.10

e9/l

0.52

284

Benign neoplasm of other and unspecified endocrine glands

250

2.25

7.47

3.3

2.2

1.01

1.14

e9/l

0.41

141

Monoplegia

4.71

7.45

2.3

1.8

1.87

1.04

e9/l

—

Benign neoplasm: Other and unspecified parts of mouth

3.94

7.45

1.2

1.7

1.06

1.15

e9/l

0.15

Otalgia

270

2.21

7.44

3.1

2.7

1.30

1.23

e9/l

0.19

175

Smoking dependency

270

2.21

7.44

2.7

2.6

1.36

1.14

e9/l

0.45

167

Acquired absence of limb

6.11

7.43

1.8

2.4

0.70

0.86

e9/l

—

Primary biliary cholangitis (PBC)

4.93

7.43

1.9

1.7

1.30

1.23

e9/l

—

Reactive arthropathies

283

2.17

7.43

2.0

2.6

1.23

1.13

e9/l

0.35

167

COPD related to multimorbidity

190

1038

1.55

7.41

1.7

2.2

1.09

1.06

e9/l

0.20

118

638

Other or ill-defined heart diseases

131

2.78

7.38

2.4

2.5

1.13

1.16

e9/l

0.06

Hypothyreosis and Thyroxine purchase for inclusion criteria

540

2754

1.30

7.38

2.3

2.4

1.16

1.17

e9/l

0.10

323

1627

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

121

708

1.72

7.37

1.9

2.5

1.25

1.18

e9/l

0.18

424

Benign neoplasm: Skin, unspecified

3.77

7.36

1.5

1.7

1.21

1.12

e9/l

0.16

Disorders of the thyroid gland

567

2884

1.29

7.33

2.3

2.4

1.16

e9/l

0.05

339

1714

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

109

361

1.82

7.32

2.4

2.1

0.99

0.95

e9/l

0.13

194

Dental caries 2 and operation codes

475

2882

1.31

7.30

2.9

2.4

1.24

1.21

e9/l

0.23

248

1758

Enteropathic arthropathies

3.89

7.28

1.4

3.1

1.22

1.10

e9/l

0.17

Alopecia areata

3.35

7.28

2.5

2.8

1.15

1.26

e9/l

0.20

Coeliac disease

456

1.90

7.27

2.8

2.7

1.28

1.18

e9/l

0.42

280

Abscess of lung

4.40

7.27

1.6

2.2

1.11

0.86

e9/l

0.53

Nystagmus and other irregular eye movements

3.79

7.26

2.7

2.8

1.24

1.56

e9/l

0.53

Dental pulpitis 2, only avohilmo

442

1693

1.34

7.26

2.4

2.3

1.25

1.15

e9/l

0.96

285

997

Mental and behavioural disorders due to tobacco

273

2.18

7.25

2.7

2.6

1.36

1.14

e9/l

0.48

169

Respiratory tuberculosis, bacteriologically and histologically confirmed

4.37

7.25

1.6

1.7

1.63

0.95

e9/l

—

Disorders of lipoprotein metabolism and other lipidaemias

435

2054

1.33

7.24

2.1

2.5

1.19

1.11

e9/l

0.83

274

1211

Obesity due to excess calories

271

1907

1.43

7.24

2.1

2.6

1.31

1.19

e9/l

1.05

152

1138

Ankylosing spondylitis, ICD10

306

2.11

7.24

1.8

2.7

0.98

1.17

e9/l

0.88

179

Malignant neoplasm of thymus

8.35

7.24

2.0

1.2

0.77

1.43

e9/l

—

Colectomy operation

507

1.85

7.20

2.3

2.2

1.25

1.09

e9/l

0.31

306

Ankylosing spondylitis

307

2.10

7.18

1.8

2.5

0.98

1.12

e9/l

0.59

189

Benign neoplasm of bone and articular cartilage

186

2.44

7.16

2.2

2.3

1.20

1.17

e9/l

0.08

Oral leukoplakia and related diseases

145

2.65

7.14

1.9

2.1

1.01

1.08

e9/l

0.19

Sixth [abducent] nerve palsy

3.23

7.14

4.0

2.4

1.37

1.11

e9/l

0.67

Other external causes of accidental injury

570

2222

1.29

7.05

2.4

2.5

1.25

1.17

e9/l

0.80

334

1359

Amyloidosis

4.27

7.04

1.3

2.0

1.16

1.11

e9/l

0.06

Congenital malformations of the musculoskeletal system, not elsewhere classified

3.96

7.04

1.1

2.9

1.64

1.39

e9/l

0.37

Other and unspecified iridocyclitis

107

2.93

7.03

1.8

2.4

1.19

1.10

e9/l

0.18

Pure hypercholesterolaemia

377

1872

1.35

7.02

2.0

2.5

1.19

1.09

e9/l

1.13

228

1110

Melanocytic naevi of trunk

270

2.16

7.02

2.2

2.3

1.08

1.22

e9/l

0.43

139

Other disorders of bladder

364

1.99

7.01

2.5

2.2

1.36

1.13

e9/l

0.69

221

Pollen allergy

149

923

1.61

7.00

2.3

2.9

1.48

1.29

e9/l

1.43

557

Tuberculosis, wide

176

2.46

7.00

1.9

2.1

1.67

1.02

e9/l

0.90

103

Essential (haemorrhagic) thrombocythaemia

3.89

6.99

1.5

1.8

1.06

1.12

e9/l

0.07

Amenorrhoea

245

2.22

6.98

3.5

2.1

1.25

1.32

e9/l

0.25

136

Cardiomyopathy (excluding other)

365

1.99

6.95

2.5

0.93

1.18

e9/l

1.57

220

Other and unspecified effects of external causes

177

1155

1.54

6.95

2.2

2.7

1.35

1.19

e9/l

1.13

114

678

Accidents

569

2222

1.29

6.95

2.4

2.5

1.26

1.17

e9/l

0.87

339

1359

Chronic suppurative otitis media, including avohilmo

278

2.14

6.95

2.3

2.7

1.45

1.19

e9/l

0.86

167

Benign neoplasm of meninges

159

2.53

6.92

2.7

2.2

1.00

1.05

e9/l

0.10

Cardiomyopathies, Primary/intrinsic

352

2.00

6.92

2.4

2.5

0.94

1.17

e9/l

1.37

219

Unspecified urinary incontinence

240

2.23

6.88

3.8

2.0

0.88

1.08

e9/l

—

160

Benign neoplasm: Skin of trunk

114

2.84

6.86

2.1

2.0

0.94

1.13

e9/l

0.64

Other Crohn's disease

215

2.30

6.86

2.4

2.8

1.04

1.21

e9/l

0.54

122

Tongue abnormality

160

2.53

6.85

1.8

2.0

1.13

1.12

e9/l

0.04

Benign neoplasm: Skin of other and unspecified parts of face

190

2.38

6.85

1.9

2.3

1.24

1.08

e9/l

0.41

113

Other and unspecified local infections of skin and subcutaneous tissue

313

2.06

6.84

3.7

2.7

1.03

1.13

e9/l

0.35

185

Malignant neoplasm of urinary organs

260

2.17

6.84

1.7

2.3

0.99

1.10

e9/l

0.45

155

Chronic suppurative otitis media

209

2.32

6.84

2.5

2.4

1.47

1.17

e9/l

0.84

116

Spirochaetal infections, other/unspecified

254

2.19

6.82

1.8

2.1

1.07

1.08

e9/l

0.02

159

Hydronephrosis

300

2.08

6.81

2.5

0.84

1.11

e9/l

2.42

177

Malignant neoplasm of tonsil

4.37

6.80

1.9

2.0

1.36

0.98

e9/l

0.50

Infective dermatitis

334

2.02

6.79

2.3

2.4

0.93

1.14

e9/l

1.70

210

Paracetamol of NSAID medication

124

363

1.73

6.78

3.1

2.9

1.20

1.16

e9/l

0.19

237

Other nutritional deficiencies

379

2783

1.33

6.76

2.1

2.5

1.27

1.19

e9/l

0.84

225

1654

HSIL lesion of the vulva

4.78

6.72

2.4

2.2

1.34

1.29

e9/l

—

Morphin

4.78

6.72

1.4

1.8

0.92

1.01

e9/l

0.16

Disorders of muscles

322

2.03

6.71

2.0

2.6

1.12

e9/l

0.00

199

Malignant neoplasm of endocrine gland

211

2.30

6.70

3.0

2.3

1.13

e9/l

0.00

131

Diseases of male genital organs

337

1240

1.38

6.66

2.8

2.6

1.15

1.12

e9/l

0.17

210

732

Moderate visual impairment, binocular

3.75

6.65

3.4

2.1

1.14

1.12

e9/l

—

Personal history of allergy to drugs, medicaments and biological substances

5.86

6.62

1.5

2.5

1.73

1.49

e9/l

—

Benign neoplasm: Small intestine

100

2.94

6.60

2.1

1.8

1.13

1.04

e9/l

0.21

Other predominantly sexually transmitted diseases, not elsewhere classified

113

670

1.70

6.60

2.5

2.4

1.32

1.25

e9/l

0.21

403

Dermatographic urticaria

200

2.32

6.59

2.9

2.4

1.71

1.17

e9/l

2.68

129

Hyperplasia of prostate

200

758

1.51

6.59

2.6

2.5

1.07

1.03

e9/l

0.18

124

446

COPD, hospital admissions 1, only main diagnosis

167

923

1.55

6.58

1.7

2.2

1.18

1.08

e9/l

0.52

573

AV-block

400

1.87

6.57

2.0

2.3

1.00

1.11

e9/l

0.48

249

Hallux valgus (acquired)

171

803

1.55

6.57

2.1

2.4

1.05

1.13

e9/l

0.41

106

481

Malignant neoplasm of kidney, except renal pelvis

245

2.18

6.56

1.7

2.2

0.99

1.09

e9/l

0.35

144

Other coagulation defects

207

2.29

6.54

2.5

2.4

1.09

1.21

e9/l

0.38

123

Other female pelvic inflammatory diseases

568

1.75

6.52

2.1

2.4

1.40

1.16

e9/l

1.24

357

Need for immunization against other single viral diseases

3.71

6.51

2.1

1.86

1.03

e9/l

2.52

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

123

2.71

6.51

2.5

2.2

1.11

1.20

e9/l

0.17

Other and unspecified follicular disorders

112

2.81

6.50

3.4

2.4

1.18

e9/l

0.01

Alzheimer disease, including avohilmo

612

0.42

6.47

2.9

1.7

1.00

1.04

e9/l

0.12

389

Acute peritonitis

171

2.42

6.45

2.3

2.1

1.10

1.09

e9/l

0.01

101

Coxibs

178

615

1.55

6.44

2.3

2.5

1.22

1.05

e9/l

1.40

389

Malignant neoplasm of stomach, excluding all cancers (controls excluding all cancers)

3.22

6.42

1.8

2.2

1.35

1.02

e9/l

0.73

Other and unspecified rosacea

254

2.14

6.41

2.4

2.3

1.12

1.17

e9/l

0.16

151

Nasal polyp

108

638

1.70

6.41

2.1

2.5

1.44

1.12

e9/l

2.34

403

Malignant neoplasm of oropharynx

4.15

6.40

1.9

2.0

1.36

0.95

e9/l

0.55

Coxarthrosis [arthrosis of hip](FG)

249

1269

1.42

6.36

2.1

2.4

1.13

1.11

e9/l

0.07

163

762

Other diseases of stomach and duodenum

148

2.52

6.36

2.1

1.28

1.06

e9/l

0.52

Cholangitis (primary sclerosing, PSC), with reimbursement 202

3.65

6.36

1.9

3.1

1.03

1.17

e9/l

0.20

Disease of hard tissues of teeth, NOS

5.59

6.32

2.8

2.2

0.98

1.00

e9/l

—

Bullous disorders

143

2.54

6.28

1.9

2.2

0.98

1.07

e9/l

0.37

Viral infections of central nervous system, not elsewhere classified/unspecified

4.79

6.25

2.6

1.8

1.50

1.06

e9/l

—

Unspecified fall

276

1986

1.38

6.25

2.2

2.5

1.15

1.20

e9/l

0.35

159

1219

Disorders of vitreous body and globe

249

1731

1.41

6.23

2.4

2.3

1.12

1.09

e9/l

0.18

155

1052

Malignant neoplasm of bronchus and lung

441

1.81

6.22

1.9

2.0

0.88

1.08

e9/l

1.67

270

Gonarthrosis [arthrosis of knee](FG)

368

1624

1.34

6.21

2.2

2.5

1.17

1.16

e9/l

0.06

227

967

Specific development disorders of scholastic skills

216

2.23

6.21

5.1

2.8

1.49

1.29

e9/l

0.42

127

Fibrosis and cirrhosis of liver

212

2.24

6.20

1.6

2.3

0.78

1.16

e9/l

2.24

126

Clear cell adenocarcinoma of kidney

115

2.73

6.20

1.9

2.2

1.06

1.03

e9/l

0.07

Other misadventures during surgical and medical care

4.02

6.19

3.6

2.4

0.95

1.03

e9/l

—

Other keratitis

374

1.91

6.19

2.4

1.29

1.15

e9/l

0.51

220

Exposure to other specified factors

440

3206

1.29

6.16

2.4

2.5

1.26

1.17

e9/l

0.95

221

1972

STROKE

328

1688

1.35

6.13

2.3

2.6

1.12

1.17

e9/l

0.45

196

970

Arthrosis

389

1617

1.33

6.13

2.1

2.5

1.22

1.13

e9/l

0.97

246

964

Convergence insufficiency and excess

4.20

6.13

1.9

1.23

1.39

e9/l

0.27

Acute epiglottitis

4.19

6.12

2.3

2.1

1.06

1.30

e9/l

—

Falls/tendency to fall

729

2976

1.23

6.12

2.3

2.5

1.28

1.18

e9/l

1.65

442

1794

Follow-up examination after treatment for malignant neoplasms

213

2.22

6.12

2.5

1.9

1.65

1.03

e9/l

1.04

152

Haemangioma and lymphangioma, any site

194

2.28

6.12

1.7

2.4

1.39

1.25

e9/l

0.15

109

Other benign neoplasms of connective and other soft tissue

194

2.28

6.11

2.8

2.2

1.13

1.19

e9/l

0.15

108

Injuries to the abdomen, lower back, lumbar spine and pelvis

208

1432

1.45

6.11

2.4

2.5

1.14

1.16

e9/l

0.13

127

867

Disorders of vitreous body

242

1688

1.41

6.09

2.3

1.13

1.09

e9/l

0.28

151

1020

Testicular hypofunction

105

2.81

6.08

3.2

2.7

1.11

1.19

e9/l

0.18

Infectious mononucleosis

307

2.00

6.07

2.8

2.7

1.18

1.21

e9/l

0.11

164

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

3.03

6.07

1.6

2.0

1.10

0.99

e9/l

0.21

Perioral dermatitis

3.65

6.06

2.1

2.5

1.39

1.35

e9/l

0.03

Congenital iodine-deficiency syndrome/hypothyroidism

3.12

6.06

1.6

2.2

1.51

1.10

e9/l

0.46

Respiratory tuberculosis, confirmed and not-confirmed

122

2.65

6.06

1.6

2.0

1.66

0.99

e9/l

0.73

Respiratory tuberculosis

122

2.65

6.06

1.6

2.0

1.66

0.99

e9/l

0.73

Benign neoplasm: Adrenal gland

122

2.64

6.06

3.1

2.1

0.89

1.06

e9/l

0.42

Other disorders starting during childhood or adolecense, excluding more controls

225

2.17

6.06

4.6

2.8

1.36

1.40

e9/l

0.07

128

Carcinoma in situ of skin of trunk

3.64

6.06

2.3

1.9

1.16

0.86

e9/l

0.69

Benign neoplasm of other and unspecified sites

3.63

6.05

1.9

1.22

1.14

e9/l

0.09

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

192

1315

1.47

6.03

2.4

2.5

1.30

1.20

e9/l

0.47

120

800

Disorders of optic nerve, not elsewhere classified

3.93

6.01

2.6

1.8

1.37

1.24

e9/l

—

Allergic contact dermatitis

464

1.80

6.01

1.6

2.5

1.16

1.20

e9/l

0.13

283

Malignant neoplasm of retroperitoneum and peritoneum, excluding all cancers (controls excluding all cancers)

4.90

6.00

1.8

1.7

0.64

1.56

e9/l

—

Short stature, not elsewhere classified

196

2.26

5.99

5.2

3.3

1.72

1.51

e9/l

0.51

130

Melanocytic naevi of lower limb, including hip

3.01

5.97

2.9

2.6

1.07

1.21

e9/l

0.28

Presence of other devices

102

606

1.69

5.94

2.3

2.1

1.08

1.10

e9/l

0.05

402

Benign neoplasm: Other and unspecified parts of small intestine

4.09

5.93

1.9

1.25

1.06

e9/l

—

Other specified/unspecified bacterial intestinal infections

178

2.33

5.93

2.1

2.3

1.31

1.09

e9/l

0.49

109

Pain in thoracic spine

510

1.75

5.93

2.1

2.5

1.27

1.14

e9/l

0.57

304

Crohn disease (strict definition, all UC cases excluded)

160

2.40

5.89

1.9

2.6

0.83

1.20

e9/l

1.60

Other disorders of binocular movement

3.00

5.88

3.3

2.8

1.26

1.30

e9/l

0.09

Other diseases of anus and rectum

147

957

1.54

5.88

2.4

1.09

1.15

e9/l

0.33

601

Cluster headache, wide,, including avohilmo

148

2.46

5.87

1.4

2.6

1.54

1.23

e9/l

1.08

Rheumatic fever incl heart disease

3.32

5.87

2.8

1.8

1.04

0.92

e9/l

0.21

Cluster headache, strict, including avohilmo

142

2.49

5.87

1.4

2.6

1.51

1.25

e9/l

0.78

Pain and other conditions associated with female genital organs and menstrual cycle

122

730

1.61

5.86

1.9

2.2

1.27

1.25

e9/l

0.08

437

Inflammation of lacrimal passages (acute and unspecified)

4.24

5.85

3.5

2.2

1.13

1.23

e9/l

—

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

319

1.95

5.84

1.9

2.1

1.08

1.16

e9/l

0.26

169

Bacterial, viral and other infectious agents

298

2.00

5.84

2.5

2.9

1.30

1.22

e9/l

0.27

181

Specific developmental disorder of motor function

129

2.60

5.82

3.4

3.1

1.73

1.49

e9/l

0.36

Dental operations, only avohilmo

413

1623

1.31

5.82

2.3

2.4

1.20

1.16

e9/l

0.35

259

954

Unspecific neurodegenerative disorder

783

0.53

5.82

2.4

1.8

1.18

1.06

e9/l

0.30

483

Cluster headache, strict

3.03

5.81

1.4

2.7

1.48

1.13

e9/l

0.77

Pneumonitis due to solids and liquids

186

2.27

5.80

2.1

2.4

1.39

1.10

e9/l

0.88

106

Vitamin deficiency, wide

131

2.55

5.79

2.7

2.3

0.97

1.07

e9/l

0.27

Vitamin deficiency

131

2.55

5.79

2.7

2.3

0.97

1.07

e9/l

0.27

Other diseases of biliary tract

225

2.15

5.78

1.8

2.3

0.92

1.09

e9/l

0.52

135

Benign neoplasm: Choroid

2.88

5.78

2.5

1.9

1.84

1.03

e9/l

0.59

Other and unspecified bullous disorders

4.79

5.78

1.2

2.0

1.10

1.16

e9/l

—

Other and unspecified coagulation defects

132

2.53

5.71

2.5

2.7

1.03

1.20

e9/l

0.49

Congenital malformations of great arteries

179

2.32

5.70

2.2

3.7

1.02

1.64

e9/l

4.04

113

Benign neoplasm of ovary

321

1.94

5.70

1.9

2.2

1.25

1.21

e9/l

0.12

181

Myopia

488

1.75

5.65

2.4

2.5

1.30

1.23

e9/l

0.27

292

Chronic Coagulation defects

3.15

5.64

2.0

2.5

1.30

1.31

e9/l

0.01

Peritonsillar abscess

120

755

1.60

5.62

2.3

2.7

1.22

1.11

e9/l

0.64

446

Other and unspecified epidermal thickening

3.23

5.62

2.5

1.36

1.17

e9/l

0.47

Dystonia

158

2.37

5.58

2.7

2.3

1.42

1.14

e9/l

1.14

Melanocytic naevi, other sites/unspecified

249

2.07

5.55

2.5

1.05

1.18

e9/l

0.65

150

Melanocytic naevi of scalp and neck

3.86

5.55

1.9

2.4

1.02

1.10

e9/l

—

Disorder of the sleep-wake schedule

3.20

5.51

1.6

3.3

1.13

1.37

e9/l

0.45

Spontaneous rupture of synovium and tendon

250

2.06

5.49

2.3

2.4

1.18

1.03

e9/l

0.51

157

Other and unspecified myopathies

230

2.10

5.49

2.2

2.4

1.14

1.07

e9/l

0.22

130

Other arthrosis

262

1369

1.37

5.48

1.9

2.5

1.20

1.10

e9/l

0.86

166

820

Benign neoplasm: Colon, unspecified

120

760

1.59

5.48

2.4

2.3

0.95

1.09

e9/l

1.04

480

Postprocedural disorders of digestive system, not elsewhere classified

2.93

5.48

1.9

2.5

1.00

1.26

e9/l

0.55

DVT of lower extremities

568

1.68

5.46

2.2

2.4

1.04

1.16

e9/l

0.55

345

Fracture of lumbar spine and pelvis

103

628

1.64

5.46

2.4

2.3

1.04

1.12

e9/l

0.32

385

Other bursopathies

427

1.79

5.45

2.1

2.6

1.04

1.09

e9/l

0.21

266

Use of anticholinesterases

637

0.46

5.45

2.4

1.8

1.28

1.04

e9/l

0.33

409

N06DA Anticholinesterases

637

0.46

5.45

2.4

1.8

1.28

1.04

e9/l

0.33

409

Cluster headache, wide

2.84

5.42

1.4

2.7

1.53

1.11

e9/l

1.06

Oral leukoplakia and related diseases, including avohilmo

272

2.00

5.41

1.9

2.2

1.13

1.11

e9/l

0.05

163

Nonorganic sleeping disorders, excluding more controls

102

623

1.64

5.41

1.9

2.4

1.41

1.19

e9/l

1.38

356

All dysplastic lesions of the vulva

112

2.62

5.40

2.3

2.4

1.23

1.21

e9/l

0.03

Cervical disc disorders

193

1354

1.43

5.38

2.2

2.4

1.41

1.10

e9/l

1.72

104

835

Substance use, excluding alcohol

119

756

1.58

5.38

2.4

2.5

1.32

1.20

e9/l

0.60

453

Dental caries 3, only avohilmo

522

2133

1.25

5.36

2.3

2.4

1.25

1.16

e9/l

1.17

315

1280

Selective serotonin reuptake inhibitors

610

2612

1.23

5.36

2.4

1.21

1.13

e9/l

1.05

357

1574

Hydrocele

357

1.86

5.35

2.4

2.6

1.12

1.04

e9/l

0.29

209

Seborrhoeic keratosis

106

656

1.62

5.34

2.4

2.2

1.17

1.12

e9/l

0.24

412

Pleural plaque

226

2.09

5.33

2.0

2.1

1.04

1.07

e9/l

0.10

137

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

166

731

1.49

5.33

2.2

2.1

1.11

1.25

e9/l

0.97

110

399

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

166

731

1.49

5.33

2.2

2.1

1.11

1.25

e9/l

0.97

110

399

Cardiomyopathy, other and unspecified

213

2.13

5.32

2.5

0.99

1.18

e9/l

0.88

128

Testicular dysfunction

119

2.56

5.31

3.4

2.8

1.11

1.15

e9/l

0.10

Total colectomy operation

119

2.55

5.30

2.2

2.6

1.11

1.20

e9/l

0.18

Total colectomy

119

2.55

5.30

2.2

2.6

1.11

1.20

e9/l

0.18

Corneal ulcer

104

642

1.63

5.30

2.4

2.5

1.26

1.17

e9/l

0.37

385

Chronic conjunctivitis

2.75

5.29

3.3

2.5

1.26

1.11

e9/l

0.25

Benign leiomyoma with endometriosis

295

1.94

5.28

2.1

1.31

1.21

e9/l

0.18

157

Crystal arthropathies, rheuma endpoint

4.68

5.28

1.3

2.0

1.01

0.93

e9/l

—

Spinal stenosis

247

1414

1.37

5.26

2.1

2.3

1.17

1.07

e9/l

0.84

141

865

Ulcer of oesophagus

169

2.27

5.23

1.8

2.5

0.90

1.08

e9/l

0.47

101

Behavioural syndromes associated with physiological disturbances and physical factors

193

1361

1.42

5.23

2.3

2.6

1.37

1.23

e9/l

1.20

129

803

Injuries to the ankle and foot

414

2973

1.27

5.23

2.4

2.5

1.23

1.20

e9/l

0.27

217

1818

Background retinopathy and retinal vascular changes

3.69

5.22

2.6

2.2

0.95

1.02

e9/l

0.13

Benign neoplasm: Cerebral meninges

144

2.37

5.22

2.8

2.2

1.02

1.07

e9/l

0.08

Decubitus ulcer and pressure area

120

2.52

5.21

1.7

2.1

0.98

1.01

e9/l

0.06

Early syphilis

4.10

5.21

4.3

2.3

1.63

1.17

e9/l

—

Other and unspecified nerve root and plexus disorders, also in other diseases

105

653

1.62

5.20

2.2

2.5

1.28

1.14

e9/l

0.92

393

Other hammer toe(s) (acquired)

426

1.75

5.19

2.0

2.2

1.26

1.13

e9/l

0.23

262

Elevated blood glucose level

256

2.01

5.18

2.4

2.8

1.00

1.17

e9/l

0.65

142

Chondropathies

577

1.66

5.17

3.1

2.4

1.39

1.18

e9/l

1.33

346

Syphilis

2.98

5.17

3.6

2.0

1.70

1.25

e9/l

1.99

Hepatic failure, not elsewhere classified

2.82

5.16

1.8

2.1

0.94

1.22

e9/l

0.76

Diseases of peritoneum

305

1.91

5.15

2.2

2.3

1.14

1.10

e9/l

0.09

185

Spondylosis

268

1711

1.35

5.14

2.2

2.3

1.20

1.09

e9/l

0.96

178

1042

Haemorrhoids and perianal venous thrombosis

138

915

1.51

5.14

2.1

2.2

1.04

1.14

e9/l

0.64

574

Vitiligo

4.30

5.13

3.1

1.8

1.14

1.40

e9/l

—

Other bullous disorders

3.04

5.12

2.0

2.2

1.01

1.16

e9/l

0.42

Scoliosis

292

1.93

5.10

2.1

2.4

1.23

1.15

e9/l

0.21

176

Presence of cardiac and vascular implants and grafts

195

1041

1.42

5.09

1.7

2.1

0.99

1.08

e9/l

0.69

111

654

Coxarthrosis

236

1164

1.38

5.07

2.2

2.4

1.12

1.10

e9/l

0.12

154

707

Fall on same level

723

3365

1.20

5.07

2.2

2.5

1.22

1.18

e9/l

0.43

432

2030

Other crystal arthropathies

4.51

5.05

1.3

2.2

1.01

0.93

e9/l

—

Preparation and fitting of bite rail to mouth

505

1.69

5.05

1.7

2.4

1.16

1.22

e9/l

0.26

302

Left ventricular outflow tract obstruction (LVOTO), broad definition

394

1.79

5.03

2.5

3.0

0.93

1.24

e9/l

2.44

241

Congenital malformations of heart and great arteries

100

600

1.62

5.03

2.5

3.0

1.06

1.35

e9/l

2.62

370

Haemangioma, any site

185

2.18

5.03

1.8

2.4

1.39

1.27

e9/l

0.11

102

Parodontitis or operation codes

493

2926

1.24

5.02

2.5

2.4

1.15

1.13

e9/l

0.15

286

1743

Other benign neoplasms of skin

189

1340

1.41

5.01

2.0

2.4

1.17

1.15

e9/l

0.09

118

824

Tooth eruption problems

600

1.63

4.98

3.4

2.8

1.45

1.22

e9/l

1.45

353

Crowding of teeth, including avohilmo

366

1.75

4.97

3.0

3.1

1.32

1.33

e9/l

0.04

229

Hypermetropia

288

1.93

4.97

2.8

2.7

1.35

e9/l

0.02

186

Motor disorders

142

2.39

4.97

3.4

3.7

1.73

1.42

e9/l

0.51

Benign neoplasm: Long bones of lower limb

3.06

4.96

2.2

2.0

1.03

1.27

e9/l

0.50

Chronic hepatitis NAS

4.15

4.92

1.1

1.9

1.34

1.29

e9/l

—

Glaucoma secondary to other eye disorders

2.69

4.92

2.0

2.1

1.09

1.15

e9/l

0.12

LSIL lesion of the vagina

4.14

4.92

1.7

2.0

1.66

1.27

e9/l

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

247

1.99

4.92

2.7

2.1

1.12

1.05

e9/l

0.28

144

Abscess of anal and rectal regions

282

1.93

4.91

1.8

2.8

1.11

1.17

e9/l

0.12

171

Cystic kidney disease

100

2.64

4.91

2.2

2.3

1.05

1.25

e9/l

0.30

Disorders of orbit

130

2.41

4.90

2.5

2.0

1.50

1.17

e9/l

0.97

Hidradenitis suppurativa

112

2.53

4.89

1.2

2.5

1.27

1.28

e9/l

0.02

Carcinoma in situ of skin of other and unspecified parts of face

155

2.27

4.89

1.9

1.8

1.12

1.00

e9/l

0.35

Parodontitis

491

2925

1.24

4.89

2.5

2.4

1.15

1.13

e9/l

0.15

284

1743

Hordeolum and other deep inflammation of eyelid

168

2.22

4.88

4.6

2.5

1.37

1.09

e9/l

0.98

102

Other diseases of arteries and capillaries

248

1.99

4.88

2.8

2.2

1.25

1.12

e9/l

0.35

154

Benign neoplasm: Stomach

283

1.92

4.87

1.8

2.0

1.22

1.06

e9/l

0.61

176

Congenital malformations of the circulatory system

106

651

1.59

4.86

3.0

2.8

1.11

1.33

e9/l

1.45

402

Chronic periodontitis, including avohilmo

489

2925

1.24

4.86

2.5

2.4

1.15

1.13

e9/l

0.16

284

1743

Psoriatic arthropathies

312

1.87

4.83

1.7

2.7

1.11

1.14

e9/l

0.07

182

Neovascular glaucoma

2.66

4.83

2.0

2.2

1.09

1.12

e9/l

0.06

D07AA Corticosteroids, weak (group I)

108

689

1.57

4.82

2.6

2.7

1.31

1.29

e9/l

0.08

410

Dental caries 1, only avohilmo

487

2001

1.25

4.82

2.2

2.4

1.29

1.14

e9/l

2.06

304

1197

Obsessive-compulsive disorder

202

2.09

4.80

2.5

2.4

1.34

1.20

e9/l

0.35

113

Cysts of oral region, not elsewhere classified

107

2.55

4.80

2.3

2.2

2.02

1.08

e9/l

1.07

Other superficial mycoses

3.21

4.79

2.3

2.7

1.31

1.17

e9/l

—

Viral hepatitis

257

1.96

4.78

3.1

2.7

1.32

1.20

e9/l

0.32

149

Disorders of continuity of bone

299

1.89

4.78

2.8

2.5

1.17

1.18

e9/l

0.04

174

Other lack of coordination

3.47

4.77

1.4

2.1

1.60

1.00

e9/l

—

Third [oculomotor] nerve palsy

3.47

4.77

2.0

1.9

1.10

1.04

e9/l

0.10

Cholecystectomy

360

2498

1.28

4.75

2.3

1.17

1.15

e9/l

0.18

227

1478

Heterophoria

300

1.88

4.74

3.7

2.8

1.23

1.19

e9/l

0.12

189

Other diseases of pancreas

210

2.06

4.73

1.7

2.2

0.96

1.05

e9/l

0.37

121

Mucosal proctocolitis

469

1.69

4.73

2.2

2.5

1.05

1.16

e9/l

0.35

281

Ulcerative ileocolitis

120

2.44

4.73

2.3

2.4

1.26

1.18

e9/l

0.10

Vascular diseases of the intestine

2.97

4.72

1.4

1.9

0.90

1.02

e9/l

—

Injuries to the wrist and hand

585

3502

1.21

4.71

2.2

2.5

1.20

1.17

e9/l

0.32

327

2134

Degeneration of macula and posterior pole

201

1197

1.39

4.68

2.0

2.2

0.99

1.09

e9/l

0.98

119

741

Ptosis of eyelid

309

1.86

4.65

2.2

2.1

1.15

1.03

e9/l

0.44

193

Pathological resorption of teeth

3.14

4.65

2.8

2.3

1.30

1.08

e9/l

—

Retinal detachments and breaks

166

1168

1.43

4.63

2.0

2.3

1.10

1.12

e9/l

0.12

722

Other localized connective tissue disorders

3.39

4.63

1.7

1.9

1.21

1.00

e9/l

—

Ankylosing spondylitis, strict definition

140

2.31

4.62

1.9

2.6

0.96

1.21

e9/l

0.64

Phobic anxiety disorders

487

1.67

4.62

2.7

1.39

1.23

e9/l

0.77

296

Examination and encounter for administrative purposes

2.77

4.62

2.0

0.96

1.13

e9/l

0.57

Non-small cell lung cancer, squamous, excluding all cancers (controls excluding all cancers)

3.51

4.61

2.2

2.7

0.87

0.97

e9/l

—

Familial hypercholesterolemia

465

1.69

4.60

2.3

2.2

1.32

1.08

e9/l

0.45

283

Hereditary deficiency of other clotting factors

4.52

4.60

1.9

2.4

0.98

1.35

e9/l

—

Exclusions for E4_PCOS_CONSORTIUM

419

2096

1.26

4.59

2.4

1.26

1.22

e9/l

0.27

259

1266

Ovarian cyst

209

874

1.39

4.58

2.1

2.2

1.32

1.22

e9/l

0.73

124

526

Ulcerative colitis (strict definition, all Crohn cases excluded)

558

1.62

4.57

1.9

2.5

1.17

1.18

e9/l

0.02

338

462

1.66

4.55

2.0

1.9

0.93

1.06

e9/l

0.84

292

Disorders of speech understanding and production

203

2.06

4.54

2.9

3.4

1.54

1.44

e9/l

0.17

123

Internal derangement of knee

193

1396

1.38

4.52

2.2

2.6

1.25

1.11

e9/l

1.18

110

831

Benign paroxysmal vertigo

139

951

1.47

4.51

2.3

1.06

1.15

e9/l

0.75

589

Hyperfunction of pituitary gland

148

2.25

4.51

3.0

2.8

1.30

1.15

e9/l

0.32

Carcinoma in situ of skin of upper limb, including shoulder

3.64

4.50

1.7

2.2

1.06

0.88

e9/l

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

463

2558

1.24

4.50

2.2

2.3

1.14

1.17

e9/l

0.34

274

1509

Personal history of other diseases and conditions

459

1.68

4.49

3.5

2.2

1.52

1.35

e9/l

0.70

285

Prurigo nodularis

3.31

4.48

1.6

1.7

1.09

1.14

e9/l

—

Benign neoplasm of eye and adnexa

300

1.85

4.42

2.6

2.1

1.43

1.13

e9/l

0.46

184

Intermittent heterotropia

265

1.90

4.41

2.7

1.23

1.36

e9/l

0.51

168

Restless leg syndrome

381

1.74

4.40

2.5

2.2

1.15

1.14

e9/l

0.04

232

Glaucoma

256

1705

1.32

4.40

2.3

1.04

1.11

e9/l

0.56

161

1030

Degenerative diseases of the nervous system

646

0.53

4.40

2.7

1.9

1.04

1.03

e9/l

0.02

401

Malignant neoplasm of eye and adnexa

4.36

4.39

1.7

2.1

1.17

0.72

e9/l

—

Chondrocostal junction syndrome [Tietze]

100

2.53

4.39

1.4

2.1

1.33

1.14

e9/l

0.37

Atypical facial pain

137

2.28

4.39

1.8

2.4

1.41

1.11

e9/l

0.86

Benign neoplasm of breast

244

1.94

4.38

2.3

1.00

1.25

e9/l

0.62

141

Injuries to the thorax

224

1673

1.34

4.36

2.3

2.4

1.27

1.13

e9/l

1.20

132

1004

Vitamin D deficiency

3.25

4.36

3.9

2.7

1.01

1.15

e9/l

0.25

Intestinal adhesions without obstruction

217

1.99

4.35

2.3

2.1

1.12

1.08

e9/l

0.08

130

conjunctival degenerations and deposits

3.25

4.35

3.3

1.9

1.05

1.06

e9/l

—

Melanocytic naevi of upper limb, including shoulder

3.38

4.34

2.6

2.1

1.05

1.12

e9/l

—

Insulin, fast-acting

202

1486

1.36

4.34

2.1

2.6

1.06

1.20

e9/l

1.39

132

899

Injuries to the neck

131

894

1.47

4.33

1.7

2.6

1.39

1.21

e9/l

0.75

528

Heartburn

288

1.85

4.32

2.4

2.7

1.29

1.10

e9/l

1.06

171

Other sleep disorders

354

1.76

4.30

2.0

2.7

1.32

1.11

e9/l

1.10

213

Open wound of lower leg

490

1.64

4.29

2.1

2.5

1.10

1.15

e9/l

0.21

293

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

139

874

1.45

4.27

2.7

1.42

1.33

e9/l

0.36

528

Other strabismus

139

960

1.45

4.27

3.0

2.7

1.28

1.26

e9/l

0.09

580

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

CD3 cells [#/volume] in Blood

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS