brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
475 |
4. Check minimum number of eventsNone |
475 |
5. Include endpointsNone |
475 |
6. Filter based on genotype QC (FinnGen only) |
427 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum oesophagi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Oesophagus
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2379 | 1167 | 1194 |
| Only index persons | 2084 | 1051 | 1033 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 61.50 | 61.77 | 61.20 |
| Only index persons | 60.86 | 60.89 | 60.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 427 | 231 | 196 |
| Unadjusted period prevalence (%) | 0.09 | 0.08 | 0.09 |
| Median age at first event (years) | 61.66 | 59.79 | 63.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 447
- Matched controls
- 4470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
+∞
307.7
435
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
15.7
162.5
361
941
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
22.6
86.7
66
34
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
42.2
80.2
49
13
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
31.2
74.9
50
18
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
27.4
57.5
40
16
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
255.7
45.9
46
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
11.3
44.8
49
48
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
5.1
44.5
113
278
UJD02
NOMESCO Finland
Gastroscopy
6.7
40.1
70
121
R13
ICD-10 Finland
Dysphagia
5.3
37.6
86
192
K22.7
ICD-10 Finland
Barrett oesophagus
12.2
32.2
33
29
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.6
31.5
85
216
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
299.3
28.1
28
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
9.8
26.8
32
35
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
4.0
26.7
89
264
A02BC05
ATC
esomeprazole; systemic
2.8
25.5
246
1353
UJF32
NOMESCO Finland
Coloscopy
2.8
23.7
173
817
UJC12
NOMESCO Finland
Flexible oesophagoscopy
29.1
22.5
30
11
R4190
NOMESCO Finland
Nutritional therapy
6.1
21.1
38
67
A02BC02
ATC
pantoprazole; systemic
3.1
20.1
362
2598
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
20.4
18.4
27
14
A02BC01
ATC
omeprazole; systemic
2.4
17.1
165
867
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
49.4
16.1
19
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
21.0
15.2
22
11
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
13.1
15.1
26
21
WX002
NOMESCO Finland
Sedation and analgesia
2.5
14.9
118
562
JCA05
NOMESCO Finland
Endoscopic polypectomy in oesophagus
154.9
14.5
15
*
Z2221
NOMESCO Finland
Medical doctor
2.3
14.3
150
808
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
14.1
131
668
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
13.9
96
427
K22.2
ICD-10 Finland
Oesophageal obstruction
15.4
13.7
22
15
JN4BD
NOMESCO Finland
Extensive body CT
2.9
13.5
73
286
A02BC03
ATC
lansoprazole; oral
2.2
13.5
165
941
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
4.4
13.5
35
85
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
13.4
47
142
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
41.4
13.2
16
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
12.8
128
670
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
12.6
101
480
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
12.6
185
1126
WX402
NOMESCO Finland
General anaesthesia
2.3
12.4
124
649
K92.1
ICD-10 Finland
Melaena
3.6
12.4
42
124
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
12.9
12.2
21
17
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.5
12.1
43
131
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
3.5
12.1
43
131
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
12.0
251
1728
D64.9
ICD-10 Finland
Anaemia, unspecified
2.7
12.0
71
291
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.3
11.7
115
595
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
11.7
80
352
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
66.7
11.7
13
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
11.2
115
605
JN4AD
NOMESCO Finland
Body CT examination
2.5
10.9
76
337
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
61.5
10.7
12
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
10.6
133
755
K30
ICD-10 Finland
Functional dyspepsia
2.5
10.4
71
312
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
10.2
64
270
J45.1
ICD-10 Finland
Nonallergic asthma
3.0
10.2
48
174
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
9.8
37
117
C16.00
ICD-10 Finland
Cardia
56.2
9.7
11
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
9.5
143
862
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
9.5
106
574
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
+∞
9.4
9
*
N03AX16
ATC
[U] pregabalin
2.0
9.4
124
714
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
9.3
57
237
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
9.3
104
562
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
9.2
52
208
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.1
9.2
25
63
K90.0
ICD-10 Finland
Coeliac disease
4.1
8.7
24
61
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
51.0
8.7
10
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
8.6
30
90
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
8.6
75
366
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
28.1
8.5
11
*
Z3231
NOMESCO Finland
Registered nurse
1.9
8.5
137
840
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
20.5
8.5
12
6
WX004
NOMESCO Finland
Patient-controlled sedation
91.7
8.4
9
*
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.4
97
529
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
8.4
138
851
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.8
8.3
43
164
WX600
NOMESCO Finland
Single shot through catheter
7.8
8.2
18
24
130
Kela drug reimbursment
Malignant tumour
2.4
8.0
56
248
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
7.9
60
276
UJC02
NOMESCO Finland
Rigid oesophagoscopy
11.1
7.8
14
13
K20
ICD-10 Finland
Oesophagitis
6.1
7.8
20
34
H02AB06
ATC
prednisolone; systemic
1.8
7.8
224
1629
WX882
NOMESCO Finland
High dependency care
4.5
7.8
19
44
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
15.4
7.8
12
8
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
7.7
62
292
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
12.1
7.6
13
11
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
12.1
7.6
13
11
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.6
7.6
45
184
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
25.5
7.6
10
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.5
7.5
18
41
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
7.9
7.4
16
21
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
81.4
7.4
8
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
7.4
65
318
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
7.3
21
55
J02AC01
ATC
fluconazole; systemic
1.8
7.3
173
1183
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
7.3
175
1202
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
16.1
7.3
11
7
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
7.5
7.2
16
22
A02BA02
ATC
ranitidine; systemic
1.9
7.2
102
595
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
7.2
61
294
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
20.4
7.2
10
5
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
7.1
88
490
H02AB07
ATC
prednisone; oral
2.1
7.1
70
358
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.5
7.1
24
71
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
7.0
71
367
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.9
140
914
A02BC04
ATC
rabeprazole; oral
2.4
6.8
50
226
R03BA01
ATC
beclometasone; inhalant
2.1
6.8
71
371
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
40.7
6.8
8
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.2
6.7
27
89
R02
ICPC
Shortness of breath/dyspnoea
2.1
6.7
73
388
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
12.5
6.6
11
9
C03CA01
ATC
furosemide; systemic
1.7
6.5
155
1055
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.5
91
528
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
6.4
165
1146
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
14.6
6.4
10
7
E66.8
ICD-10 Finland
Other obesity
2.9
6.4
29
103
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.9
6.4
95
563
R53
ICD-10 Finland
Malaise and fatigue
1.8
6.4
123
789
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
11.2
6.3
11
10
R4110
NOMESCO Finland
Physiotherapy
1.7
6.3
134
884
N06AX21
ATC
duloxetine; oral
2.1
6.2
61
312
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.8
6.2
13
17
K29.4
ICD-10 Finland
Chronic atrophic gastritis
4.2
6.1
16
39
J01MA02
ATC
ciprofloxacin; systemic
1.7
6.1
183
1319
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
289
1814
2.68
21.77
8.4
5.1
35.25
35.57
g/l
0.45
278
1709
325
2191
2.77
20.70
8.6
6.9
10.99
11.31
umol/l
0.24
312
2086
104
398
3.10
20.60
3.1
2.5
0.21
0.21
g/l
0.23
96
372
199
1075
2.53
20.10
3.0
2.1
2.82
3.01
mg/l
0.54
178
932
221
1302
2.38
17.87
3.4
2.6
54.55
124.68
u/l
0.60
203
1212
394
3054
3.45
17.38
11.9
8.5
82.16
79.80
u/l
0.34
375
2887
290
1975
2.33
16.05
19.4
14.5
1.25
1.25
inr
0.00
236
1629
299
2087
2.31
15.25
13.5
7.1
1.21
1.21
mmol/l
0.15
264
1803
278
1893
2.24
14.92
12.7
6.3
1.21
1.21
mmol/l
0.13
256
1745
116
548
2.51
14.92
11.8
5.9
1.05
1.03
mmol/l
0.51
110
502
321
2375
2.25
13.25
10.5
5.0
6.78
6.75
mmol/l
0.10
304
2261
130
701
2.20
12.04
4.0
2.5
10.79
13.11
umol/l
3.47
123
655
84
380
2.49
11.63
2.7
2.5
37.25
31.59
u/l
0.61
63
319
302
2244
2.07
11.45
12.7
10.2
4.38
4.13
e9/l
0.96
259
1957
259
1825
2.00
11.38
4.6
3.0
114.46
131.56
ug/l
0.62
243
1687
96
472
2.32
11.00
3.6
3.1
6.22
8.48
umol/l
0.94
82
424
78
361
2.41
10.21
14.1
7.9
9.73
10.03
mmol/l
0.12
72
347
97
495
2.23
10.11
16.3
7.4
0.78
0.87
mmol/l
0.06
81
413
255
1834
1.91
10.04
2.6
2.2
97.38
95.49
pmol/l
0.26
153
973
68
300
2.49
9.86
3.2
3.4
208.92
214.12
ng/l
0.04
62
272
98
512
2.17
9.60
16.3
7.2
12.36
12.20
kpa
0.09
92
493
98
512
2.17
9.60
16.3
7.2
5.02
5.14
kpa
0.54
92
492
251
1818
1.87
9.45
4.4
2.8
—
—
estimate
—
0
0
154
959
1.92
9.25
4.7
2.4
—
—
—
0
0
41
150
2.91
8.54
1.7
1.6
19.24
11.41
u/ml
—
5
25
195
1336
1.82
8.51
4.8
3.5
28.50
31.25
u/l
1.16
184
1263
64
298
2.34
8.21
1.9
1.7
—
—
—
0
0
351
2914
1.95
7.76
5.6
4.4
14.76
12.23
mm/h
1.87
322
2703
65
312
2.27
7.76
5.2
3.6
111.14
82.90
ng/l
1.35
56
272
131
816
1.86
7.64
4.7
4.0
565.88
299.79
ng/l
0.25
101
658
319
2582
1.82
7.48
4.7
3.4
60.03
51.25
u/l
0.58
290
2414
86
474
2.01
7.18
2.9
4.6
7.54
36.43
ug/l
1.00
77
398
23
70
3.41
6.50
1.5
1.5
—
—
—
0
0
23
70
3.41
6.50
1.5
1.5
—
—
—
0
0
416
3747
2.59
6.47
31.1
16.8
24.75
24.19
mg/l
0.14
369
3088
41
185
2.34
5.64
2.0
1.7
1.37
1.49
g/l
0.41
35
166
173
1250
1.63
5.62
2.1
1.7
21.05
20.97
nmol/l
0.03
154
1040
60
320
2.01
5.45
1.6
1.5
—
—
—
0
0
72
415
1.88
5.21
4.5
4.0
1.51
1.91
mmol/l
0.32
67
356
161
1167
1.59
5.05
4.4
3.4
0.32
0.46
e6/l
0.74
119
858
25
94
2.76
5.00
1.5
1.4
—
—
—
0
0
190
1435
1.56
4.98
3.9
3.6
2.34
2.35
mmol/l
0.53
174
1295
225
1768
1.55
4.92
3.2
2.5
73.96
77.68
nmol/l
1.33
199
1573
109
728
1.66
4.72
2.0
1.7
1140.30
1190.97
nmol/l
0.19
80
547
31
135
2.39
4.64
1.6
1.4
329.45
288.26
ug/g
0.59
26
79
389
3511
1.83
4.49
6.5
5.4
1.91
1.96
mu/l
0.35
364
3193
121
842
1.60
4.42
3.3
3.0
2.46
2.45
mmol/l
0.25
106
755
145
1056
1.55
4.34
3.2
2.9
345.55
347.37
umol/l
0.06
128
917
105
710
1.63
4.30
3.8
3.0
0.91
1.09
e6/l
0.15
49
379
417
3866
2.17
4.23
37.0
20.1
139.49
139.68
mmol/l
0.88
412
3792
24
97
2.56
4.20
2.5
3.2
1.46
1.86
index
0.15
13
63
417
3870
2.16
4.15
37.5
20.3
3.96
3.99
mmol/l
1.02
412
3790
98
657
1.63
4.15
3.9
3.2
3.02
2.05
e6/l
0.32
43
326
128
918
1.55
4.07
1.9
1.7
0.96
1.38
mg/l
2.09
99
737
32
151
2.21
4.01
2.5
1.9
467.85
300.16
ug/l
0.31
32
143
127
912
1.55
4.01
1.4
1.3
0.54
1.33
u/ml
2.70
32
247
84
546
1.66
4.00
2.2
1.9
—
—
—
0
0
334
2951
1.52
3.62
5.0
4.3
14.70
14.90
pmol/l
0.75
314
2664
103
722
1.55
3.58
2.4
2.0
—
—
—
0
0
14
46
3.11
3.56
1.3
1.3
—
—
—
0
0
40
216
1.94
3.54
1.7
1.3
—
—
—
0
0
253
2127
1.44
3.48
4.4
3.9
0.00
3.49
estimate
0.50
49
465
201
1621
1.44
3.47
4.5
4.0
35.22
37.31
ng/l
0.11
136
1207
250
2104
1.43
3.37
4.4
3.9
0.00
0.00
estimate
0.50
46
453
8
14
5.80
3.35
2.9
3.3
0.57
0.59
mmol/l
—
8
14
24
111
2.23
3.18
1.1
1.2
—
—
—
0
0
76
513
1.58
3.10
2.3
2.0
—
—
—
0
0
252
2145
1.40
3.07
4.4
4.0
0.00
0.71
estimate
0.50
49
429
170
1354
1.41
3.05
4.3
3.5
82.42
51.65
e6/l
0.23
130
1039
65
428
1.61
2.94
1.9
1.6
1.84
1.52
%
0.98
50
363
14
52
2.75
2.91
1.7
1.4
—
—
—
0
0
16
64
2.56
2.90
1.3
1.4
—
—
—
0
0
14
53
2.69
2.82
1.7
1.4
—
—
—
0
0
14
53
2.69
2.82
1.7
1.4
—
—
—
0
0
170
1372
1.39
2.76
3.4
3.2
1328.16
1343.37
ng/l
0.02
140
1175
52
332
1.64
2.67
3.1
2.8
59.91
65.00
ml/min/173m2
0.43
23
137
23
113
2.09
2.66
1.1
1.2
—
—
—
0
0
43
261
1.72
2.66
1.9
1.7
—
—
—
0
0
18
82
2.25
2.51
5.8
6.9
3905.40
454.69
iu/ml
—
5
13
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
24
123
2.01
2.50
4.3
2.5
0.23
0.34
iu/ml
1.77
11
67
99
742
1.43
2.43
1.4
1.3
26.72
30.89
iu/ml
0.13
39
240
24
125
1.97
2.40
1.6
3.6
6.90
2.39
ratio
0.34
12
71
423
4045
1.85
2.31
46.1
25.7
4.37
4.48
e12/l
4.31
416
3954
423
4045
1.85
2.31
46.1
25.7
252.74
246.74
e9/l
0.93
418
3967
13
53
2.50
2.29
1.8
1.4
—
—
—
0
0
121
951
1.37
2.25
3.1
2.8
5.68
4.73
e6/l
0.29
112
865
23
123
1.92
2.15
1.2
1.4
—
—
—
0
0
416
3969
1.69
2.15
18.8
12.6
25.42
25.51
u/l
0.05
405
3850
13
55
2.40
2.14
1.8
1.4
—
—
—
0
0
13
55
2.40
2.14
1.8
1.4
—
—
—
0
0
392
3692
1.50
2.13
6.3
5.4
6.02
6.00
mmol/l
0.07
365
3367
7
20
3.54
2.06
1.9
2.3
—
—
—
0
0
80
597
1.41
2.01
1.6
1.5
—
—
—
0
0
24
134
1.84
1.99
1.8
1.9
—
—
—
0
0
331
3041
1.34
1.98
40.2
22.2
329.76
331.83
g/l
3.51
331
3026
30
180
1.71
1.97
1.3
1.4
—
—
—
0
0
6
16
3.79
1.94
1.0
2.8
534.33
731.69
u/ml
—
6
16
58
414
1.46
1.85
4.2
3.6
—
—
—
0
0
49
340
1.50
1.80
8.4
4.2
1.23
1.23
mmol/l
0.35
42
297
20
109
1.87
1.80
1.6
1.7
—
—
—
0
0
50
350
1.48
1.77
2.0
2.5
6.28
8.03
ug/l
0.36
44
310
20
110
1.86
1.76
1.5
1.9
—
—
—
0
0
26
156
1.71
1.73
2.7
3.0
—
—
—
0
0
87
676
1.36
1.72
1.3
1.3
26.45
10.29
u/ml
0.70
36
271
20
111
1.84
1.71
1.6
1.3
—
—
—
0
0
105
842
1.32
1.69
2.0
1.8
448.91
15643715.85
pmol/l
0.80
87
684
23
135
1.74
1.66
1.7
1.3
—
—
—
0
0
7
25
2.83
1.65
2.0
1.5
25.43
30.50
umol/l
—
7
20
36
240
1.54
1.60
4.4
3.3
3.02
2.12
mmol/l
0.59
29
179
243
2179
1.25
1.57
3.2
2.8
—
—
—
0
0
27
169
1.64
1.56
1.9
1.5
0.41
0.32
mg/l
0.32
13
70
18
101
1.81
1.51
1.1
1.3
—
—
—
0
0
29
187
1.59
1.50
1.2
1.1
—
—
—
0
0
9
38
2.40
1.46
1.7
1.2
—
—
—
0
0
21
125
1.71
1.46
1.3
1.2
—
—
—
0
0
18
103
1.78
1.43
1.5
1.4
—
—
—
0
0
5
18
2.80
1.29
1.4
1.3
—
—
—
0
0
164
1433
1.23
1.28
3.6
3.4
7.00
7.49
mmol/l
0.84
143
1202
378
3611
1.30
1.23
7.5
6.9
39.59
39.76
mmol/mol
0.13
346
3368
17
101
1.71
1.21
2.9
2.2
111.17
127.77
g/l
1.88
12
78
181
1605
1.21
1.21
4.2
3.9
0.00
0.03
estimate
1.55
44
376
8
38
2.12
1.19
1.3
1.4
324.13
554.64
u/l
—
8
38
8
38
2.12
1.19
1.0
1.3
—
—
—
0
0
6
128
0.46
1.18
3.0
1.8
34.50
40.87
nmol/l
—
6
121
17
102
1.69
1.18
1.5
1.2
—
—
—
0
0
10
50
2.02
1.17
4.0
4.0
—
—
—
0
0
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
5
20
2.52
1.15
1.8
1.7
47.58
54.98
ug/l
—
5
20
8
41
1.97
1.09
1.1
1.1
—
—
—
0
0
135
1174
1.21
1.09
3.4
3.4
0.02
0.08
estimate
0.38
43
369
30
213
1.44
1.05
5.0
3.1
18.78
90.53
u/ml
0.74
30
207
18
114
1.60
1.04
1.8
1.5
—
—
—
0
0
381
3662
1.27
1.03
27.5
16.7
78.44
78.48
ml/min/173m2
0.01
363
3406
9
47
1.93
1.02
1.1
1.1
—
—
—
0
0
19
123
1.57
1.01
1.5
1.6
—
—
—
0
0
159
1414
1.19
1.00
4.5
4.2
6.54
8.90
mg/mmol
0.61
106
872
107
917
1.22
0.99
4.3
4.2
1.02
1.02
kg/l
0.68
76
629
371
3560
1.25
0.98
4.6
4.5
1.28
1.28
mmol/l
0.03
336
3237
7
37
1.91
0.94
1.1
1.1
—
—
—
0
0
7
37
1.91
0.94
1.1
1.1
—
—
—
0
0
7
37
1.91
0.94
1.1
1.1
—
—
—
0
0
6
27
2.24
0.94
3.0
1.8
223.83
194.19
e6/l
—
6
21
13
78
1.69
0.92
1.2
1.7
—
—
—
0
0
64
525
1.26
0.89
1.7
1.5
—
—
—
0
0
16
103
1.57
0.88
1.7
1.7
5.47
4.36
iu/l
—
7
40
17
112
1.54
0.86
1.2
1.2
—
—
—
0
0
182
1657
1.17
0.85
2.1
2.0
1.34
1.35
mmol/l
0.04
151
1370
8
47
1.71
0.81
1.1
1.9
—
—
—
0
0
10
58
1.74
0.80
1.2
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
5
24
2.10
0.74
2.0
1.7
—
—
—
0
0
9
56
1.62
0.72
1.1
1.1
—
1.34
—
0
9
383
3717
1.21
0.71
5.4
5.3
1.42
1.47
mmol/l
1.41
349
3412
13
85
1.55
0.69
1.7
1.6
—
—
—
0
0
19
259
0.72
0.67
1.6
1.9
3.44
3.47
mmol/l
0.07
11
198
7
44
1.60
0.65
1.3
1.6
—
—
—
0
0
7
44
1.60
0.65
1.3
1.6
—
—
—
0
0
7
44
1.60
0.65
1.3
1.6
—
—
—
0
0
384
3735
1.20
0.65
5.5
5.4
4.47
4.59
mmol/l
1.55
352
3446
5
29
1.73
0.64
2.2
1.7
558.60
503.25
e6/l
—
5
20
5
30
1.67
0.61
1.2
1.2
—
—
—
0
0
5
30
1.67
0.61
1.2
1.2
—
—
—
0
0
8
50
1.61
0.61
1.1
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
7.38
—
0
21
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
8
53
1.52
0.58
2.4
1.9
—
—
—
0
0
15
106
1.43
0.58
1.2
1.2
—
1.00
—
0
8
6
35
1.72
0.58
1.2
1.1
—
—
—
0
0
28
349
0.79
0.55
2.1
2.1
3.77
3.45
ratio
0.77
20
288
9
62
1.46
0.53
1.1
1.5
—
—
—
0
0
6
39
1.55
0.53
1.2
1.1
1.32
1.90
nmol/l
—
6
34
16
117
1.38
0.53
1.4
1.6
—
—
—
0
0
388
3793
1.17
0.52
6.5
6.2
2.60
2.66
mmol/l
0.76
357
3487
11
75
1.48
0.51
1.6
1.3
—
—
—
0
0
60
524
1.17
0.49
5.4
5.1
33.74
31.96
%
0.80
43
332
19
146
1.31
0.47
1.4
1.3
31.41
26.20
iu/l
0.27
14
125
13
94
1.39
0.46
10.2
3.4
15.25
9.27
pmol/l
0.71
13
94
5
31
1.62
0.43
1.6
1.1
—
—
—
0
0
10
139
0.71
0.42
1.5
1.8
4.28
4.17
mg/l
—
10
109
5
33
1.52
0.41
1.4
1.5
—
62.00
—
0
5
5
33
1.52
0.41
1.0
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
7
102
0.68
0.40
2.6
1.8
148.00
222.84
pmol/l
—
7
94
7
101
0.69
0.40
1.0
1.1
1.34
1.57
g/l
—
7
101
10
71
1.42
0.39
1.6
1.6
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
16
124
1.30
0.39
1.2
1.2
—
2.72
—
0
17
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
13
98
1.34
0.38
1.2
1.3
—
—
—
0
0
16
125
1.29
0.37
1.2
1.2
—
2.57
—
0
26
14
111
1.27
0.30
1.5
1.5
—
—
—
0
0
10
76
1.32
0.28
1.8
1.2
—
—
—
0
0
76
819
0.91
0.27
2.8
3.2
0.54
0.78
ug/l
3.17
53
542
31
274
1.14
0.25
2.3
1.9
—
—
—
0
0
5
38
1.32
0.23
8.2
2.3
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
2.37
—
0
6
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
126
1209
1.06
0.19
4.7
4.0
0.00
0.01
estimate
0.74
46
425
12
101
1.19
0.16
1.7
1.5
—
—
—
0
0
133
1376
0.95
0.16
5.3
5.6
1.39
2.62
ug/l
3.48
117
1227
12
102
1.18
0.15
3.1
2.6
38.71
109.45
ug/min
—
7
60
9
107
0.84
0.13
2.3
1.7
—
—
—
0
0
9
108
0.83
0.13
1.3
1.2
0.99
0.89
g/l
—
9
108
51
483
1.06
0.12
8.3
6.9
—
—
—
0
0
11
95
1.16
0.11
1.4
1.2
—
49.38
—
0
13
27
251
1.08
0.10
2.1
1.8
—
—
—
0
0
10
87
1.15
0.09
1.4
1.5
—
—
—
0
0
6
55
1.09
0.09
1.0
1.0
—
—
—
0
0
11
98
1.13
0.07
1.1
1.4
1.45
14.73
e6/l
1.00
11
71
9
100
0.90
0.06
1.8
1.4
—
—
—
0
0
23
243
0.94
0.05
1.3
1.2
125.52
129.67
u/ml
—
9
100
11
100
1.10
0.05
1.1
1.4
6.55
1333.68
e6/l
0.59
11
75
109
1103
0.98
0.03
4.1
4.6
22.12
21.39
%
0.17
50
540
15
147
1.02
0.00
2.4
1.6
—
—
—
0
0
10
98
1.02
0.00
1.1
1.4
3.68
3.82
mmol/l
—
10
91
16
158
1.01
0.00
2.5
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
57
0.88
-0.00
1.4
1.3
0.55
0.35
nmol/l
—
5
42
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
27.31
—
0
8
5
53
0.94
-0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.18
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_OESOPHAGUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 1.743 [1.42, 2.14] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.605 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 904 females with CD2_BENIGN_OESOPHAGUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 2.397 [1.96, 2.94] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 951 males with CD2_BENIGN_OESOPHAGUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_OESOPHAGUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.182% | 0.547% |
| 5 | 1.21% | 2.914% |
| 10 | 2.852% | 6.638% |
| 15 | 5.388% | 13.23% |
| 20 | 9.566% | 20.951% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_OESOPHAGUS – Benign neoplasm: Oesophagus
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data