Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3005532	pf-mononuk	% (%)	543	720	5.97%
3005532	pf-ly	% (%)	394	490	0.00%
3005532	pf-mononuk	— (—)	144	178	100.00%	Distribution not available
3005532	pf-lymf	% (%)	136	173	2.31%
3005532	pf-lymf	— (—)	117	142	100.00%	Distribution not available
3005532	pf-mn	— (—)	14	16	100.00%	Distribution not available
3005532	pf-ly	— (—)	13	14	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Other pleural conditions

314

38.57

307.65

1.6

1.2

63.55

61.09

0.23

265

Pleural effusion

607

129

51.94

307.65

1.6

1.2

64.74

61.44

0.45

522

Other diseases of pleura

779

312

22.92

307.65

1.5

1.2

64.49

59.23

1.51

660

234

Lung cancer and mesothelioma

200

25.33

255.23

1.3

1.4

66.62

67.02

0.03

175

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

314

384

7.28

201.04

1.4

62.44

62.85

0.06

268

305

Pneumonia, organism unspecified

449

621

5.26

194.91

1.4

56.10

65.98

5.35

361

520

Heart failure,strict

362

402

6.58

193.86

1.5

1.3

65.58

58.71

2.23

283

333

Heart failure, not strict

411

493

5.80

192.25

1.5

1.2

65.45

58.90

2.37

327

418

Pneumonias (Asthma/COPD co-morbidities)

456

635

5.00

184.35

1.3

1.4

55.64

65.61

5.51

369

528

All pneumoniae

456

635

4.98

183.30

1.3

1.4

55.30

65.90

6.16

369

528

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

452

645

4.95

181.78

1.3

1.4

55.69

65.87

5.74

367

535

Heart failure, strict

389

544

5.20

166.10

1.5

1.3

66.00

61.49

1.35

305

450

Influenza and pneumonia

445

625

4.71

164.68

1.4

54.90

65.92

6.50

359

523

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

416

526

4.98

160.56

1.4

55.28

66.29

5.91

336

436

416

526

4.98

160.56

1.4

55.28

66.29

5.91

336

436

Other pulmonary diagnosis

271

142

9.60

155.99

1.4

1.3

61.91

62.67

0.08

231

110

All-cause Heart Failure

371

538

5.02

152.65

1.5

1.3

67.02

61.53

1.83

289

444

Other medical care

291

515

5.58

150.70

1.5

1.3

62.36

64.07

0.31

241

416

Excluding asthma or asthma-COPD overlap

264

142

9.35

149.68

1.4

1.3

62.86

62.67

0.02

223

110

COPD differential diagnosis

263

142

9.31

148.78

1.4

1.3

62.60

62.89

0.03

224

109

ILD differential diagnosis

262

142

9.28

147.87

1.4

1.3

62.52

62.89

0.04

223

109

Heart failure and antihypertensive medication

190

119

10.69

138.27

1.6

1.2

63.14

61.88

0.12

146

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

213

249

7.30

133.68

1.4

66.53

65.32

0.16

186

199

Asthma, unspecified (mode), excluding more controls

141

13.23

129.10

1.4

1.2

59.47

61.67

0.20

118

Other bacterial diseases

419

733

3.97

128.95

1.5

1.3

59.18

62.93

1.11

337

607

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

171

226

7.69

121.48

1.3

1.4

63.12

64.41

0.16

145

185

Asthma, unspecified (mode)

155

127

9.72

118.49

1.4

1.3

59.87

64.54

0.62

128

Bacterial infection, other or unspecified

303

617

4.47

118.44

1.5

1.4

61.06

63.57

0.50

241

509

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

145

162

9.12

118.26

1.3

1.4

61.93

62.82

0.09

128

135

Renal tubulo-interstitial diseases

380

783

3.74

111.79

1.5

1.3

62.42

61.96

0.08

286

663

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

178

219

6.89

106.15

1.3

1.4

66.63

64.71

0.26

158

177

Other heart diseases

169

140

8.01

102.17

1.6

1.2

59.92

55.31

0.60

137

124

Other heart diseases, wide

308

441

4.35

102.02

1.5

1.3

63.43

58.00

1.45

243

385

Asthma, excluding more controls

166

9.64

99.95

1.4

1.2

59.33

60.35

0.09

137

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

325

820

3.70

99.56

1.5

1.4

61.97

63.23

0.24

272

666

Suppurative and necrotic conditions of lower respiratory tract

12.87

98.06

1.6

1.4

34.82

67.31

7.71

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

392

833

3.39

97.85

1.4

62.78

61.48

0.27

312

691

Renal failure

282

646

4.03

96.82

1.6

1.4

62.36

63.84

0.25

205

537

Abnormal findings on diagnostic imaging of lung

279

686

4.00

96.57

1.4

63.00

63.46

0.07

233

557

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

141

180

7.52

95.72

1.3

1.4

65.07

66.22

0.13

124

147

COPD (mode)

125

103

9.70

95.46

1.4

1.3

59.47

65.69

0.76

103

Pyothorax

13.71

91.92

1.6

1.4

34.43

66.14

6.23

Diseases of the respiratory system

187

127

7.40

91.37

1.5

1.2

63.30

62.49

0.08

157

Heart failure and bmi 25plus

200

264

5.28

85.43

1.5

1.3

68.99

61.96

1.68

159

227

Asthma

177

141

6.75

83.99

1.4

1.3

59.42

62.89

0.44

146

109

Non-ischemic cardiomyopathy

186

298

5.18

83.58

1.5

1.3

65.82

61.59

0.74

146

250

Chronic kidney disease

207

469

4.45

82.92

1.6

1.3

61.39

64.54

0.53

148

393

Persons encountering health services for specific procedures and health care

373

729

3.18

80.72

1.4

1.3

61.07

61.14

0.01

301

600

Malignant neoplasm, wide definition for exclusion

300

486

3.66

78.55

1.4

65.12

60.16

1.31

255

384

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

300

486

3.66

78.54

1.4

65.12

60.16

1.31

255

384

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

300

487

3.66

78.33

1.4

65.12

60.09

1.35

255

385

Non-rheumatic valve diseases

208

333

4.59

78.26

1.6

1.3

65.82

58.73

1.72

165

288

Dyspnoea

350

867

3.11

77.80

1.5

1.3

66.57

60.78

2.16

275

719

Valvular heart disease excluding rheumatic fever

207

333

4.57

77.57

1.6

1.3

65.82

58.73

1.72

165

288

Septicaemia

222

536

4.02

77.25

1.5

1.3

58.25

63.64

1.21

172

438

Bacterial Sepsis

244

589

3.71

74.47

1.6

1.3

57.46

65.02

2.23

189

485

Explicit Sepsis

227

570

3.85

74.44

1.5

1.3

58.01

64.62

1.70

177

466

Malignant neoplasm

304

522

3.47

73.86

1.4

65.48

60.05

1.54

258

416

Atrial fibrillation and flutter

126

108

7.66

73.27

1.6

1.2

63.42

57.33

0.71

Implicit Sepsis

303

726

3.26

73.21

1.5

1.3

60.59

63.37

0.62

234

601

Asthma (only as main-diagnosis), excluding more controls

126

8.18

73.15

1.4

1.2

57.82

60.35

0.24

104

Later onset COPD, excluding more controls

9.31

71.31

1.4

1.2

65.66

67.22

0.12

Asthma (mode)

159

142

6.16

71.01

1.5

1.3

58.19

62.89

0.64

134

109

Atrial fibrillation and flutter with reimbursement

117

8.12

70.32

1.5

1.2

65.89

58.50

0.87

Other septicaemia

199

493

3.99

69.21

1.5

1.3

60.16

64.49

0.84

151

403

Fever of other and unknown origin

234

614

3.55

67.87

1.4

56.25

64.07

2.30

183

517

Malignant neoplasm of respiratory system and intrathoracic organs

177

379

4.36

67.46

1.4

66.48

66.99

0.07

152

298

Cardiac arrhythmias

173

242

4.74

65.19

1.5

1.3

65.67

56.64

2.02

135

215

Implicit bacterial Sepsis

214

541

3.66

64.46

1.6

1.3

58.54

64.76

1.52

164

440

Non-small cell lung cancer

141

291

4.93

64.02

1.3

1.4

65.07

68.69

0.58

124

226

Any event in cancer register

292

543

3.20

63.05

1.4

65.21

60.01

1.44

247

436

Other diseases of pericardium

15.91

62.50

1.5

1.2

50.61

53.87

0.16

Diseases of arteries, arterioles and capillaries (FINNGEN)

102

7.80

62.36

1.6

1.2

54.24

58.16

0.33

Oxycodone

192

494

3.79

61.85

1.4

61.46

64.61

0.54

157

394

Asthma (only as main-diagnosis)

136

141

5.83

60.72

1.4

1.3

57.13

62.89

0.82

112

109

Acute renal failure

136

285

4.83

60.58

1.7

1.3

60.61

66.20

0.94

107

240

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

10.59

59.86

1.3

62.72

63.42

0.05

COPD/asthma related infections

315

526

3.01

58.07

1.4

58.25

66.29

3.07

269

436

COPD/asthma/ILD related infections

315

526

3.01

58.07

1.4

58.25

66.29

3.07

269

436

Condition for Implicit Sepsis (Organ dysfunction codes)

294

748

2.87

56.33

1.6

1.3

61.19

62.72

0.28

223

622

Any gastric operation

215

285

3.79

55.49

1.4

62.26

64.90

0.40

171

235

GASTRO-related operations

215

285

3.79

55.49

1.4

62.26

64.90

0.40

171

235

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

18.56

52.62

1.2

67.43

54.00

0.81

First line medication for Crohn's disease

344

715

2.63

51.80

1.4

1.3

58.41

63.67

1.68

283

592

Aplastic and other anaemias

223

698

3.05

50.98

1.4

63.81

65.02

0.19

177

564

Abnormalities of breathing

280

582

2.87

50.66

1.5

1.3

63.53

60.19

0.74

223

485

Primary_lymphoid and hematopoietic malignant neoplasms

114

245

4.69

49.24

1.6

1.4

66.52

64.61

0.19

196

Ascites

7.48

49.24

1.6

1.5

66.69

63.55

0.29

Dialysis, with operation codes

158

5.65

46.78

1.7

1.3

58.68

65.22

0.75

129

Malignant neoplasm of bronchus and lung

143

352

3.85

46.60

1.3

1.4

66.43

67.25

0.10

125

274

Heart failure and coronary heart disease

201

475

3.18

46.24

1.5

1.4

66.38

64.97

0.22

153

384

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

293

776

2.57

45.19

1.4

62.07

61.69

0.06

229

648

Other anaemias

203

659

2.99

45.15

1.4

63.79

64.69

0.13

159

532

Respiratory insufficiency

13.68

44.98

1.7

1.4

58.24

69.88

0.78

Other and unspecified anaemias

199

655

2.96

43.45

1.4

63.89

64.72

0.11

157

528

Nephropathy related operations

166

5.32

43.32

1.7

1.3

58.95

63.50

0.46

136

Other disorders of fluid, electrolyte and acid-base balance

151

421

3.49

43.14

1.5

1.4

61.07

65.12

0.68

121

349

Cardiovascular diseases (excluding rheumatic etc)

120

146

4.76

43.04

1.5

1.2

55.41

56.19

0.07

100

129

Valvular operations

113

6.34

42.64

1.5

1.3

65.66

57.70

0.99

Cardiomyopathy

139

5.66

41.75

1.4

1.3

61.75

56.77

0.47

122

Care involving dialysis

7.22

41.12

1.7

1.4

62.95

62.35

0.04

Non-small cell lung cancer, adenocarcinoma

103

6.57

40.57

1.3

1.5

62.72

67.24

0.43

Non-small cell lung cancer, adenocarcinoma, helper endpoint

103

6.57

40.57

1.3

1.5

62.72

67.24

0.43

Cerebrovascular diseases (FINNGEN)

112

5.58

40.38

1.3

1.2

55.80

57.89

0.17

Oral corticosteroids

329

858

2.33

39.85

1.4

1.3

54.35

64.26

4.49

256

713

Diseases of arteries, arterioles and capillaries

268

807

2.49

39.58

1.5

1.4

60.73

63.31

0.53

210

666

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

105

6.22

38.72

1.3

66.69

58.94

0.96

Pneumothorax

9.92

38.34

1.7

1.2

59.06

54.36

0.24

Hypertensive diseases (excluding secondary)

109

140

4.54

37.29

1.5

1.2

55.18

55.84

0.05

124

Early onset COPD, excluding more controls

7.17

37.18

1.5

1.4

51.79

66.00

1.74

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

127

5.57

36.83

1.7

1.4

64.25

64.18

0.01

103

Certain infectious and parasitic diseases

270

540

2.51

36.31

1.5

1.3

62.71

63.33

0.09

219

454

Any reimbursement code in KELA

5.12

35.91

1.5

1.2

52.71

56.22

0.30

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

141

5.23

35.86

1.5

1.4

61.38

63.87

0.20

117

Extracorporeal dialysis

6.90

34.86

1.7

1.5

64.05

58.19

0.43

ILD medications: prednisolone, methylprednisolone, prednisone

320

819

2.21

34.04

1.5

1.3

55.32

64.11

3.67

250

686

Cardiovascular diseases

103

125

4.50

33.97

1.5

1.2

55.80

54.24

0.13

110

Pleural plaque

6.26

32.58

1.4

1.2

74.55

63.03

1.34

Persons encountering health services in other circumstances

127

401

3.18

31.87

1.3

1.4

64.33

61.46

0.35

347

Metabolic disorders

278

768

2.25

31.73

1.5

1.3

61.71

62.84

0.19

223

641

Benign neoplasm of colon, rectum, anus and anal canal

154

371

2.98

31.67

1.5

1.4

61.97

62.54

0.06

125

292

Inflammatory bowel disease treatment related agents

323

861

2.14

31.64

1.5

1.3

54.21

64.17

4.56

252

716

AV-block

143

4.73

31.49

1.6

1.3

60.92

60.84

0.01

122

Benign neoplasms

175

347

2.86

31.30

1.5

1.4

63.97

60.76

0.50

146

279

Neoplasms

173

324

2.87

30.55

1.5

1.4

60.61

60.92

0.03

143

260

Infections, IBD-co-morbidities

5.21

30.17

1.6

1.3

62.08

58.48

0.31

Malignant neoplasm of heart, mediastinum and pleura

14.20

29.94

1.8

1.4

67.45

66.36

0.04

L01XE Protein kinase inhibitors

6.75

29.81

1.3

1.5

71.53

59.07

1.24

Type 2 diabetes, wide definition

254

732

2.27

29.81

1.4

64.60

61.17

0.80

210

599

General symptoms and signs

296

680

2.19

29.65

1.4

58.37

63.60

1.45

236

574

Persons encountering health services in other circumstances, wide

342

868

2.05

29.45

1.5

1.3

65.01

60.85

1.21

262

726

Erysipelas

179

642

2.55

29.41

1.5

1.4

62.34

63.37

0.14

147

527

Primary_lymphoid and hematopoietic malignant neoplasms

114

356

3.23

29.27

1.6

1.4

66.52

65.87

0.06

294

Parasetamol

208

417

2.55

29.22

1.5

1.3

62.54

61.10

0.21

174

339

Complications of surgical and medical care, not elsewhere classified

284

960

2.13

29.21

1.5

1.3

62.67

62.15

0.08

229

788

Conduction disorders

100

231

3.62

29.21

1.5

1.3

66.22

61.54

0.60

200

Paroxysmal tachycardia

5.42

29.02

1.5

1.2

64.59

58.57

0.52

Other arrhythmias

149

403

2.84

28.83

1.6

1.3

60.91

58.34

0.33

113

352

Bacterial pneumoniae

134

404

2.95

28.77

1.4

54.43

67.51

3.70

115

333

ILD medications

310

820

2.08

28.21

1.5

1.3

55.48

64.09

3.51

242

687

Benign neoplasm: Colon

138

366

2.90

27.75

1.4

62.13

63.17

0.12

114

289

Iron deficiency anaemia

158

602

2.61

27.66

1.4

65.41

63.87

0.21

120

494

Implicit viral Sepsis

224

3.78

27.51

1.5

1.4

54.97

67.67

2.05

188

Viral Sepsis

224

3.78

27.51

1.5

1.4

54.97

67.67

2.05

188

Presence of other functional implants

211

640

2.34

27.26

1.4

65.81

63.74

0.35

165

534

Opioids

261

622

2.21

27.20

1.4

63.92

62.80

0.19

220

505

Cardiomyopathy (excluding other)

100

5.34

26.78

1.3

54.95

59.63

0.31

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

138

382

2.83

26.68

1.3

1.4

55.46

63.79

1.69

113

304

Hypertension, essential

196

457

2.45

26.41

1.6

1.3

62.32

60.69

0.24

161

378

Anaemia in chronic diseases classified elsewhere

10.00

26.01

1.6

1.3

62.99

58.55

0.17

Acute tubulo-interstitial nephritis

183

682

2.39

25.98

1.4

1.3

61.68

63.16

0.21

144

579

Bacterial pneumonia, not elsewhere classified

126

391

2.86

25.73

1.5

1.4

54.95

67.62

3.29

108

324

Coronary atherosclerosis

224

645

2.25

25.73

1.5

1.4

63.35

62.13

0.19

177

537

Hypo-osmolality and hyponatraemia

235

3.59

25.55

1.4

61.28

66.85

0.73

188

Gout, FINNGEN

135

504

2.70

25.24

1.4

63.34

64.91

0.18

421

Gout

135

455

2.72

25.20

1.4

63.34

64.56

0.13

382

Cardiomyopathies, Primary/intrinsic

5.30

25.08

1.4

1.2

57.19

57.42

0.01

Polyarthropathies

217

649

2.23

24.85

1.5

1.4

55.72

62.73

1.72

155

541

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

135

3.91

24.75

1.6

1.2

62.27

56.20

0.64

119

Insulin medication

195

738

2.27

24.44

1.4

62.72

61.21

0.24

159

596

Bleeding

254

897

2.07

24.41

1.5

1.4

60.08

63.05

0.63

202

736

Secondary uncertain malignant neoplasm

202

3.75

24.30

1.5

1.4

64.87

67.34

0.23

160

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

155

3.68

24.18

1.4

1.3

69.49

55.20

2.97

123

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

155

3.68

24.18

1.4

1.3

69.49

55.20

2.97

123

Peripheral artery disease

184

641

2.32

24.03

1.4

62.74

64.31

0.22

135

529

Non-allergic asthma (mode), excluding more controls

7.24

23.84

1.4

1.2

62.13

64.74

0.14

Nutritional anaemias

174

732

2.32

23.66

1.4

65.13

64.22

0.12

130

606

Presence of cardiac and vascular implants and grafts

179

580

2.35

23.63

1.4

65.36

63.05

0.38

137

480

Ischemic heart diseases

234

691

2.13

23.43

1.5

1.4

63.81

61.22

0.49

188

577

Symptoms and signs involving the circulatory and respiratory systems

246

582

2.12

23.12

1.5

1.3

64.01

60.19

0.85

200

485

Codes for special purposes

131

504

2.61

23.06

1.4

64.32

62.43

0.25

114

420

Asthma-related pneumonia

139

554

2.52

22.72

1.3

1.4

53.04

64.93

3.12

108

451

Non-follicular lymphoma, hilmo, excluding all cancers

5.22

22.66

1.9

1.3

66.36

62.74

0.25

Asthma, hospital admissions 3, pneumonia

139

555

2.51

22.63

1.3

1.4

53.04

64.93

3.12

108

451

Asthma-related pneumonia or sepsis

139

555

2.51

22.63

1.3

1.4

53.04

64.93

3.12

108

451

Provisional assignment of new diseases of uncertain etiology

130

504

2.59

22.54

1.4

64.03

62.54

0.19

113

420

Pacemaker

151

610

2.42

22.52

1.4

61.38

65.78

0.80

116

489

Other and unspecified iron deficiency

118

439

2.70

22.24

1.3

1.4

65.87

64.69

0.13

363

Haemorrhage from respiratory passages

125

441

2.64

22.22

1.4

59.38

62.52

0.42

105

364

Complications of procedures, not elsewhere classified

222

931

2.07

22.17

1.5

1.4

62.25

62.16

0.01

180

766

Viral pneumonia

110

4.67

22.14

1.5

59.38

69.56

1.00

Hard cardiovascular diseases

233

722

2.08

22.13

1.4

61.99

61.92

0.01

187

603

Diabetic nephropathy, excluding more controls

159

3.71

21.26

1.4

62.74

63.68

0.07

133

Pulmonary heart disease, diseases of pulmonary circulation

126

499

2.54

20.98

1.4

63.62

64.72

0.13

100

406

Insulin, intermediate and long-acting

180

822

2.15

20.57

1.4

63.56

62.63

0.13

149

666

Atherosclerosis, excluding cerebral and coronary sclerosis

171

618

2.22

20.22

1.4

63.19

64.57

0.18

129

510

Covid-19 confirmed case

354

2.81

20.18

1.4

1.5

63.22

65.10

0.20

289

Hypertensive heart and/or renal disease

104

288

2.81

20.00

1.4

1.3

57.64

64.12

1.00

232

Ischaemic heart disease, wide definition

225

699

2.02

19.81

1.4

63.72

61.62

0.37

179

584

Hyperlipidaemia, other/unspecified

144

588

2.33

19.70

1.4

62.46

64.09

0.21

112

482

COPD

169

636

2.20

19.68

1.4

61.52

63.45

0.28

139

512

Diabetes, varying definitions

253

782

1.94

19.62

1.4

64.28

60.94

0.78

215

635

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

246

775

1.94

19.34

1.4

64.87

60.85

1.04

209

632

Other respiratory disorders and diseases

352

2.78

19.29

1.6

1.4

60.52

66.26

0.84

274

Other diseases of the respiratory system

352

2.78

19.29

1.6

1.4

60.52

66.26

0.84

274

Other chronic obstructive pulmonary disease, including avohilmo

191

768

2.08

19.25

1.4

62.24

63.25

0.14

159

623

Hernia of abdominal wall, postoperative

108

4.37

18.90

1.2

1.4

68.58

64.99

0.28

Other chronic obstructive pulmonary disease

163

621

2.19

18.85

1.4

61.27

63.43

0.31

133

501

Insulin, combination of fast acting with intermediate-acting or long-acting

195

889

2.03

18.84

1.4

62.72

62.55

0.02

159

719

Diabetes mellitus

251

784

1.91

18.83

1.4

64.15

60.85

0.77

212

638

Secondary and unspecified malignant neoplasm of lymph nodes

113

4.30

18.77

1.6

1.5

65.28

63.18

0.13

Volume depletion

144

3.86

18.64

1.5

1.4

65.87

67.34

0.10

118

Hypertensive diseases

177

460

2.18

18.54

1.6

1.3

59.86

60.74

0.11

147

380

Hypertension

177

460

2.18

18.53

1.6

1.3

59.86

60.74

0.11

147

380

Other diseases of blood and blood-forming organs, wide

283

2.95

18.51

1.5

1.4

64.16

65.07

0.08

227

Drug-induced neutropenia

5.13

18.36

1.4

1.5

64.12

58.48

0.37

Bacterial pneumonia (organism specified)

153

634

2.21

18.34

1.5

1.4

54.21

65.65

3.40

131

512

Chronic periapical parodontitis

260

3.02

18.11

1.3

1.4

54.24

63.47

1.35

215

Pulmonary embolism

112

451

2.50

18.08

1.3

1.4

62.62

65.16

0.32

369

Pulmonary heart disease

112

451

2.50

18.08

1.3

1.4

62.62

65.45

0.37

368

Asthma-related infections

164

764

2.12

18.03

1.3

1.4

55.34

63.86

2.19

130

627

Asthma, hospital admission 2, infections

164

764

2.12

18.03

1.3

1.4

55.34

63.86

2.19

130

627

Disorders of lens

196

605

2.05

18.02

1.4

64.26

61.63

0.47

157

499

Chronic lower respiratory diseases

294

885

1.80

17.86

1.5

1.4

60.61

62.34

0.34

246

720

Gout, idiopatic and unspecified

107

426

2.53

17.74

1.5

1.4

61.18

64.36

0.35

359

Invasive ventilation

4.44

17.54

1.5

1.4

57.55

63.18

0.43

Cardiodefibrillation

140

630

2.23

17.52

1.5

1.4

65.36

61.97

0.53

112

514

Non-allergic asthma (mode)

5.27

17.50

1.4

62.13

66.60

0.29

Diabetes, insulin treatment (Kela reimbursement)

259

862

1.84

17.43

1.4

65.65

60.51

1.60

220

701

Glomerular disorders in diseases classified elsewhere

170

3.50

17.41

1.4

57.37

64.08

0.66

134

Insulin, fast-acting

114

472

2.42

17.32

1.4

58.11

62.20

0.62

393

Glomerular diseases

267

2.94

17.32

1.5

1.4

59.51

64.78

0.60

215

Hyperkalaemia

4.77

17.31

1.5

1.4

43.46

67.02

2.65

Antihypertensive medication - note that there are other indications

172

2.93

17.24

1.5

1.2

56.51

58.91

0.22

143

Explicit bacterial Sepsis

125

3.95

17.22

1.3

1.4

50.52

65.10

1.56

102

All influenza

226

3.11

17.17

1.4

51.31

68.04

2.78

189

Adjustment and management of implanted device

263

2.95

17.16

1.7

1.4

69.39

64.75

0.56

209

Vocal cord dysfunction

5.00

17.08

1.6

1.2

54.07

61.95

0.46

Type 2 diabetes

244

779

1.86

16.93

1.4

63.94

60.81

0.68

206

634

Venous thromboembolism

175

845

2.02

16.87

1.3

1.4

63.78

63.30

0.06

139

686

malignant neoplasm of female genital organs

146

3.65

16.71

1.2

1.4

66.28

61.92

0.44

123

Agranulocytosis

128

3.86

16.68

1.4

1.5

63.52

63.83

0.02

105

Endocrine, nutritional and metabolic diseases

174

418

2.12

16.59

1.6

1.3

62.66

61.92

0.09

141

347

COPD, hospital admissions

166

686

2.06

16.44

1.4

61.98

64.60

0.41

136

560

Persons with potential health hazards related to communicable diseases

267

2.87

16.41

1.3

1.4

68.55

58.91

1.45

225

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

142

3.44

16.39

1.3

72.63

56.69

3.00

113

Tramadol

190

615

1.99

16.30

1.4

57.53

62.98

1.22

153

499

COPD, hospital admission 2, with asthma infections

130

494

2.26

16.28

1.3

1.4

60.44

65.37

0.75

102

399

DVT of lower extremities and pulmonary embolism

143

671

2.13

16.08

1.3

1.4

62.94

64.49

0.20

115

548

Senile cataract

187

582

2.00

16.07

1.4

64.61

61.91

0.47

148

482

COPD, early/later onset

166

691

2.04

16.02

1.4

61.98

64.74

0.43

136

565

Malaise and fatigue

141

545

2.16

15.91

1.4

64.62

64.51

0.01

109

460

Hydronephrosis

138

3.65

15.75

1.3

1.4

60.85

64.32

0.29

112

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

134

410

2.24

15.74

1.4

65.83

62.65

0.47

111

328

Other retinal disorders

198

838

1.90

15.66

1.3

1.4

63.31

62.79

0.07

148

696

Diseases of liver

108

458

2.37

15.65

1.5

1.4

60.52

63.73

0.41

386

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

4.05

15.57

1.4

1.3

61.94

58.76

0.18

Disorders of lipoprotein metabolism and other lipidaemias

219

739

1.87

15.54

1.4

60.48

63.21

0.50

171

613

Diseases of pulp and periapical tissues

102

423

2.42

15.53

1.3

1.4

57.09

62.96

0.89

350

Complications of medical and surgical care

193

975

1.88

15.26

1.6

1.3

61.49

62.81

0.19

155

803

Streptococcal septicaemia

105

4.04

15.22

1.3

1.4

49.41

63.07

1.23

Glucagon-like peptide-1 (GLP-1) analogues

174

731

1.96

15.17

1.4

66.32

61.99

0.90

138

587

Major coronary heart disease event

215

777

1.85

15.06

1.5

1.4

64.85

62.98

0.33

170

640

Need for other prophylactic measures

5.14

15.06

1.3

1.4

70.00

55.84

1.07

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

125

381

2.26

14.99

1.4

66.42

63.63

0.39

105

304

Factors influencing health status and contact with health services

166

2.76

14.96

1.4

1.3

62.26

59.32

0.27

139

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

123

375

2.26

14.88

1.5

1.4

65.80

63.88

0.23

101

300

Insulin, fast-acting or short human

114

506

2.26

14.86

1.4

58.11

63.31

0.87

420

Disorders of gallbladder, biliary tract and pancreas

254

936

1.75

14.79

1.3

1.4

60.06

62.28

0.43

206

767

Gout, unspecified

355

2.52

14.79

1.5

1.4

60.84

65.04

0.47

298

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

226

2.94

14.72

1.6

1.5

57.27

64.91

0.92

184

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

122

374

2.26

14.68

1.5

1.4

65.08

64.05

0.11

101

299

STROKE

139

454

2.13

14.56

1.4

58.69

61.26

0.36

115

386

Other bacterial intestinal infections

255

2.80

14.51

1.6

1.4

61.43

67.89

0.77

206

COPD related to multimorbidity

146

601

2.05

14.47

1.4

63.39

64.13

0.09

119

485

Gout, strict definition

318

2.60

14.45

1.5

1.4

56.86

65.56

1.05

268

Myocardial infarction

162

584

2.00

14.44

1.5

1.4

62.82

62.16

0.09

125

486

Coronary revascularization (ANGIO or CABG)

156

540

2.02

14.29

1.4

64.23

62.11

0.31

120

448

Disorders of choroid and retina

226

929

1.77

14.13

1.3

1.4

64.41

62.13

0.43

171

770

Infections of the skin and subcutaneous tissue

139

679

2.04

14.07

1.4

60.79

61.85

0.13

117

561

Benign neoplasm: Colon, unspecified

247

2.79

14.04

1.4

63.39

62.94

0.03

199

Persons encountering health services for other counselling and medical advice, not elsewhere classified

258

852

1.73

14.02

1.5

1.3

67.11

60.68

2.12

197

713

Autoimmune diseases excluding thyroid diseases, strict definition

246

788

1.74

13.66

1.4

1.3

58.07

63.26

1.39

200

646

Diabetic nephropathy

255

2.73

13.59

1.4

1.5

62.74

63.78

0.08

218

Autoimmune diseases excluding thyroid diseases

252

812

1.72

13.52

1.4

1.3

57.61

62.95

1.47

205

667

Diseases of oesophagus, stomach and duodenum

258

922

1.70

13.48

1.5

1.4

61.33

62.19

0.14

196

770

Intestinal infectious diseases

223

994

1.75

13.46

1.4

59.27

62.76

0.73

169

824

Calcific aortic valvular stenosis, operated

121

562

2.12

13.40

1.5

1.4

68.20

64.78

0.53

447

Calcific aortic valvular stenosis

121

562

2.12

13.40

1.5

1.4

68.20

64.78

0.53

447

Calcific aortic valvular stenosis, diagnosis (helper)

121

562

2.12

13.40

1.5

1.4

68.20

64.78

0.53

447

Operations 2 for CAVS

121

562

2.12

13.40

1.5

1.4

68.20

64.78

0.53

447

Calcific aortic valvular stenosis, including rheumatic fever

121

562

2.12

13.37

1.5

1.4

68.20

64.78

0.53

447

Bacterial intestinal infections, IBD co-morbidities

261

2.70

13.36

1.6

1.4

61.96

66.72

0.51

210

Acute peritonitis

4.02

13.36

1.5

1.4

55.36

65.82

0.90

Cirrhosis of liver, NAS

4.62

13.31

1.4

63.71

56.26

0.47

Cardiomyopathy, other and unspecified

4.72

13.29

1.4

1.3

61.23

57.88

0.15

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

140

2.80

13.23

1.4

1.3

55.33

63.12

0.87

115

Diabetes medication

238

837

1.73

13.20

1.4

63.57

61.26

0.47

206

678

Benign neoplasms

238

766

1.74

13.12

1.5

1.3

63.33

61.88

0.25

199

626

Enterocolitis due to Clostridium difficile

162

3.17

12.99

1.6

1.4

58.55

66.94

0.79

127

Pain in throat and chest

178

579

1.88

12.98

1.4

1.3

61.12

60.32

0.10

137

482

Type 1 diabetes, wide definition, subgroup 1

194

2.95

12.85

1.3

1.4

59.98

61.69

0.14

158

Other disorders of skin and subcutaneous tissue

183

928

1.81

12.79

1.4

64.38

62.84

0.23

145

765

Coronary artery bypass grafting

109

378

2.20

12.74

1.5

1.4

64.35

62.65

0.20

312

Emergency coronary revascularization (for ACS)

189

755

1.80

12.49

1.4

64.39

63.07

0.20

140

620

COPD, hospital admissions 3, with asthma pneumonia sepsis

110

436

2.16

12.46

1.3

1.4

60.40

66.01

0.78

347

Enlarged lymph nodes

156

3.16

12.43

1.3

1.5

55.92

67.27

1.18

133

Non-small cell lung cancer, squamous, excluding all cancers (controls excluding all cancers)

4.58

12.37

1.3

1.4

66.50

68.00

0.08

Contact with and exposure to communicable diseases

188

2.92

12.24

1.3

1.5

70.76

56.19

1.92

161

Asthma (diagnoses ohter than nonallergic)

203

1002

1.73

12.19

1.4

58.23

63.46

1.28

166

820

ILD medications: immunosuppressive drugs

133

649

1.97

12.15

1.4

1.3

52.11

63.86

2.61

551

Fibrosis and cirrhosis of liver

3.88

12.08

1.5

62.70

60.33

0.13

Hypertensive Heart Disease

274

2.43

12.01

1.4

1.3

56.53

64.35

1.17

220

Codeine

200

618

1.78

12.00

1.4

62.75

62.65

0.01

165

502

Type 2 diabetes, definitions combined

221

768

1.72

12.00

1.4

63.91

60.86

0.61

185

626

Dialysis

5.71

11.96

1.4

1.3

62.74

63.34

0.02

Iron deficiency anaemia secondary to blood loss (chronic)

225

2.73

11.93

1.4

1.5

63.23

65.16

0.15

183

Major coronary heart disease event excluding revascularizations

194

760

1.77

11.90

1.5

1.4

63.74

62.91

0.12

146

626

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

5.41

11.83

1.3

1.4

68.57

60.28

0.44

Other cataract

126

487

2.01

11.71

1.4

63.98

63.38

0.06

404

Oedema, not elsewhere classified

407

2.23

11.62

1.4

57.47

66.44

1.40

343

Peripheral arterial reconstruction

329

2.39

11.59

1.4

62.73

67.21

0.48

262

Myocardial infarction, strict

146

560

1.91

11.57

1.5

1.4

61.87

61.97

0.01

112

464

ILD, hospital admissions 3, with pneumonia sepsis

3.75

11.55

1.5

53.13

72.21

1.63

Misadventures to patients during surgical and medical care

174

2.95

11.53

1.8

1.4

68.30

65.47

0.23

143

Type 2 diabetes, strict (exclude DM1)

221

780

1.69

11.40

1.4

63.91

60.77

0.64

185

636

Gastric ulcer

296

2.45

11.32

1.3

1.4

62.17

64.70

0.22

248

Symptoms and signs involving the urinary system

200

909

1.70

11.10

1.4

61.18

63.03

0.30

156

748

Other acute lower respiratory infections

143

735

1.86

11.07

1.3

1.4

59.86

63.64

0.62

114

603

Diseases of the skin and subcutaneous tissue

245

745

1.65

11.06

1.5

1.4

64.11

61.84

0.45

205

602

Diabetic retinopathy, excluding more controls

181

2.47

11.05

1.3

61.03

63.73

0.26

153

Non-follicular lymphoma

152

3.05

11.03

1.9

1.4

66.36

67.79

0.09

124

Gastroduodenal ulcer

472

2.10

10.89

1.3

1.4

60.88

64.71

0.44

397

Type 1 diabetes, wide definition

225

2.63

10.81

1.3

1.4

60.15

61.70

0.13

182

Bronchitis

244

994

1.61

10.65

1.3

1.4

58.06

63.43

1.44

195

816

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

3.86

10.65

1.3

1.4

65.85

64.62

0.06

Autoimmune diseases

257

815

1.61

10.64

1.5

1.3

57.19

63.04

1.69

209

669

Unspecified kidney failure

146

3.04

10.48

1.5

1.4

64.24

66.49

0.12

119

Used for control exclusion in common control thyroid runs

241

751

1.63

10.39

1.5

1.3

58.94

63.47

1.11

196

616

Type 2 diabetes, definitions combined, including avohilmo

216

772

1.66

10.34

1.4

64.59

60.50

0.92

183

629

Diseases of peritoneum

142

3.05

10.33

1.5

1.6

55.91

64.26

0.75

115

Paralytic ileus and intestinal obstruction

391

2.18

10.33

1.4

62.25

64.92

0.28

324

Symptoms and signs involving the digestive system and abdomen

240

742

1.62

10.18

1.5

1.4

62.58

61.46

0.18

198

607

Type 1 diabetes

274

2.41

10.16

1.3

1.4

61.76

61.02

0.06

227

Alcoholic liver disease

150

2.96

10.02

1.7

1.4

55.62

64.96

0.92

121

ILD, hospital admission 2, with pulmonary infections

109

3.33

9.98

1.5

54.88

74.90

1.85

Other dialysis

5.51

9.95

1.4

1.3

66.56

59.32

0.32

Dental caries

311

2.30

9.94

1.4

51.84

64.12

2.00

257

Coagulation defects, purpura and other haemorrhagic conditions

242

2.49

9.88

1.6

1.4

60.52

65.26

0.49

196

Colorectal cancer, excluding all cancers (controls excluding all cancers)

299

2.30

9.81

1.4

53.68

65.13

1.60

237

In situ neoplasms

313

2.26

9.76

1.5

1.4

63.76

62.97

0.07

252

Care involving use of rehabilitation procedures

130

673

1.84

9.73

1.4

1.3

64.66

61.15

0.53

110

554

257

865

1.57

9.69

1.3

1.4

59.54

64.59

1.37

207

713

Transplanted organ and tissue status

3.58

9.64

1.5

1.4

56.39

58.67

0.09

Hepatic failure, not elsewhere classified

5.06

9.58

1.4

1.3

69.57

54.81

0.86

Non-invasive ventilation

114

3.14

9.51

1.5

1.3

69.46

59.41

0.98

Diarrhoea and gastroenteritis of presumed infectious origin

156

825

1.72

9.32

1.3

1.4

59.56

63.06

0.58

117

688

Benign neoplasm of colon, rectum, anus and anal canal

172

929

1.67

9.28

1.4

61.75

63.17

0.21

141

756

Asthma/COPD (KELA code 203)

203

885

1.62

9.22

1.4

59.14

62.34

0.63

168

720

Dentinal caries

274

2.33

9.16

1.4

1.5

51.41

64.39

2.06

225

Viral pneumonia (unknown virus, not influenza)

4.00

9.05

1.5

63.10

58.98

0.17

Complications of cardiac and vascular prosthetic devices, implants and grafts

5.59

9.01

1.7

1.4

72.30

60.39

—

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

3.47

8.91

1.7

1.4

71.44

61.30

0.86

Later onset COPD

111

462

1.89

8.86

1.4

67.37

65.69

0.19

367

Angina pectoris

157

619

1.72

8.84

1.5

1.4

64.54

62.40

0.33

128

515

Amputation

179

2.64

8.75

1.4

51.84

67.24

2.02

144

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

124

3.01

8.73

1.2

1.5

56.49

66.63

0.89

Disorders resulting from impaired renal tubular function

4.60

8.61

1.5

1.3

60.82

59.56

0.05

Injuries to the head

238

1010

1.54

8.58

1.4

60.59

62.06

0.25

191

829

Cholelithiasis, broad definition with cholecystitis

206

892

1.58

8.57

1.3

1.4

64.03

62.93

0.16

162

731

Benign neoplasm: Sigmoid colon

164

2.69

8.54

1.5

1.4

52.75

63.54

1.05

134

Ulcer of lower limb, not elsewhere classified

236

2.39

8.46

1.5

1.4

68.74

65.77

0.26

190

Peripheral artery operations in Hilmo

226

2.40

8.28

1.4

54.25

67.14

1.59

183

Intestinal stricture

476

1.94

8.25

1.4

61.01

64.64

0.43

387

Other (not insulin) diabetes medications

214

829

1.56

8.11

1.4

64.66

61.08

0.81

188

671

Other symptoms and signs involving the digestive system and abdomen

158

2.67

8.03

1.4

62.03

63.89

0.13

133

Syncope and collapse

114

564

1.79

7.92

1.5

1.4

64.42

64.93

0.05

472

Pure hypercholesterolaemia

173

717

1.62

7.91

1.5

1.4

62.32

63.59

0.18

137

593

Cutaneous abscess, furuncle and carbuncle

288

2.19

7.89

1.5

1.4

59.80

63.27

0.32

235

Diagnoses used for exclusion with ILD

408

1.99

7.87

1.5

1.4

69.05

65.14

0.45

332

Cough

430

1.94

7.86

1.3

62.47

61.47

0.10

359

Stroke, including SAH

176

814

1.60

7.83

1.4

60.19

63.72

0.67

139

665

Other or unspecified ileus, impaction or obstruction

289

2.19

7.82

1.3

1.4

62.88

66.19

0.30

237

Purpura and other haemorrhagic conditions

172

2.57

7.82

1.7

1.4

60.79

65.35

0.40

139

Retention of urine

111

521

1.81

7.81

1.4

63.66

64.21

0.06

424

Injuries to the hip and thigh

131

701

1.71

7.81

1.3

1.4

63.25

64.17

0.10

104

571

Osteoporosis

370

2.02

7.79

1.3

1.5

62.37

67.40

0.58

308

Genitourinary diseases

141

409

1.73

7.72

1.4

1.3

63.43

60.06

0.47

110

356

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

128

2.83

7.67

1.5

1.4

62.24

64.27

0.12

103

Ischaemic Stroke, excluding all haemorrhages

167

786

1.61

7.60

1.4

61.22

63.98

0.46

130

645

Neurological diseases, wide definition

115

2.45

7.59

1.4

1.3

59.07

58.52

0.03

100

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

211

2.38

7.56

1.3

1.4

56.00

64.36

0.76

166

Gastrointestinal diseases

115

316

1.83

7.52

1.5

1.3

59.10

63.65

0.61

263

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

143

865

1.65

7.51

1.5

1.4

59.63

63.43

0.59

117

713

Other disorders of kidney and ureter

188

2.46

7.47

1.4

1.5

68.80

64.35

0.40

151

Psychiatric diseases

245

821

1.50

7.47

1.4

58.14

63.85

1.60

210

671

Constipation

206

966

1.53

7.47

1.5

1.4

65.53

62.30

0.65

163

799

Other diseases of the digestive system

544

1.83

7.43

1.5

1.4

61.39

63.36

0.21

447

Other respiratory diseases principally affecting the interstitium

309

2.11

7.42

1.4

63.74

68.41

0.43

253

Unspecified acute lower respiratory infection

183

2.47

7.38

1.4

1.5

57.97

62.91

0.39

148

Benign neoplasm: Colon

145

869

1.64

7.38

1.4

61.49

63.96

0.37

120

709

Stroke, excluding SAH

171

801

1.59

7.38

1.4

61.10

63.64

0.42

134

656

Cholelithiasis

194

881

1.55

7.37

1.3

1.4

64.13

62.92

0.18

153

723

GI-bleeding

100

553

1.81

7.35

1.5

1.4

61.88

63.50

0.17

454

Biguanides

213

864

1.52

7.34

1.4

65.56

61.03

1.13

182

699

Cerebrovascular diseases

192

892

1.54

7.29

1.4

62.14

63.35

0.19

150

733

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

110

2.92

7.26

1.5

1.4

59.28

65.53

0.41

Diseases of the eye and adnexa

161

493

1.64

7.24

1.4

62.25

60.71

0.21

131

414

Malignant neoplasm of breast

353

1.88

7.22

1.4

1.3

68.13

61.85

1.07

294

L04AD Calcineurin inhibitors

100

3.01

7.18

1.5

56.73

59.02

0.09

Diverticular disease of intestine

180

765

1.57

7.16

1.4

60.94

63.57

0.41

142

630

Congenital malformations of heart and great arteries

107

2.91

7.15

1.3

1.5

60.37

56.51

0.24

Benign neoplasm of other and ill-defined parts of digestive system

139

2.67

7.13

1.2

1.4

53.66

60.23

0.43

118

140

786

1.64

7.10

1.4

52.68

63.15

2.89

124

636

Malnutrition

5.74

7.08

1.8

1.3

53.50

62.53

—

External causes of morbidity and mortality

152

463

1.65

7.01

1.6

1.3

62.58

63.04

0.05

121

381

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

219

957

1.49

6.98

1.5

1.4

65.23

61.57

0.80

173

790

Non-small cell lung cancer, squamous, helper endpoint

3.02

6.93

1.3

1.6

66.50

69.48

0.18

Non-small cell lung cancer, squamous

3.02

6.93

1.3

1.6

66.50

69.48

0.18

Benzodiazepine use

216

1034

1.49

6.92

1.4

59.04

62.68

0.78

183

838

Diseases of the musculoskeletal system and connective tissue

115

328

1.76

6.75

1.5

1.3

58.08

62.75

0.65

273

Adrenocortical insufficiency

5.04

6.71

1.5

1.3

55.22

61.57

—

Diseases of the digestive system

125

756

1.65

6.67

1.5

1.4

61.39

63.13

0.22

620

Osteopathies and chondropathies

124

710

1.66

6.67

1.4

59.57

63.49

0.54

599

Other embolism and thrombosis

168

2.45

6.66

1.5

65.61

65.77

0.01

139

Acute bronchitis

104

588

1.74

6.64

1.3

1.4

58.07

64.43

0.96

485

Other disorders of teeth and supporting structures

276

2.11

6.64

1.5

1.4

57.02

65.65

1.15

225

Other CVD

337

2.00

6.61

1.4

1.5

66.85

67.44

0.05

265

Other diseases of intestines

213

833

1.49

6.59

1.4

60.17

62.19

0.33

173

689

Mycoses

351

1.97

6.59

1.3

1.4

53.85

64.70

1.49

289

Other symptoms and signs involving the urinary system

163

2.47

6.58

1.4

60.23

67.67

0.60

133

Coronary angioplasty

109

488

1.72

6.46

1.5

1.4

63.54

62.11

0.16

405

Dysphagia

328

1.99

6.37

1.5

1.4

58.11

63.71

0.64

273

Malignant neoplasm of breast, HER2-negative

355

1.82

6.34

1.4

1.3

67.72

61.97

0.91

296

495

1.79

6.31

1.3

1.4

55.97

64.19

1.39

409

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

204

2.26

6.28

1.3

1.4

55.82

63.62

0.74

164

Dermatitis

132

826

1.60

6.23

1.4

60.37

63.27

0.43

113

672

Other and unspecified dermatitis

112

674

1.66

6.19

1.4

60.94

63.26

0.30

561

Hypertensive Renal Disease

3.54

6.17

1.3

60.25

67.30

0.31

Vascular disorders of the intestines

104

2.81

6.15

1.4

1.5

65.34

69.60

0.26

Myocardial infarction, without ST-elevation

126

721

1.62

6.12

1.4

64.68

63.96

0.08

586

141

804

1.57

6.10

1.4

52.68

62.98

2.81

124

652

Other disorders of adrenal gland

4.32

6.03

1.5

1.3

57.70

55.19

—

Benign neoplasm: Rectum

164

2.39

6.02

1.6

1.4

64.63

62.48

0.17

136

Benign neoplasm of other and unspecified endocrine glands

2.93

5.99

1.5

1.3

64.05

58.78

0.28

ILD, hospital admissions

261

2.08

5.99

1.4

60.31

68.90

0.78

213

Finngen Rheumatological endpoints

200

774

1.47

5.96

1.4

1.3

62.05

62.31

0.03

153

649

Candidiasis

141

2.49

5.92

1.4

1.5

55.11

65.00

0.81

114

Unspecified jaundice

3.13

5.89

1.3

1.5

58.71

66.26

0.40

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

125

2.54

5.79

1.4

1.3

59.44

57.49

0.11

Malignant neoplasm of skin

169

849

1.50

5.78

1.5

1.4

62.36

64.64

0.37

143

690

Diabetic retinopathy

100

368

1.72

5.77

1.3

1.4

63.35

63.98

0.06

305

Alcohol use disorder, Swedish definition

129

759

1.58

5.75

1.4

52.22

63.07

2.88

114

613

Benign neoplasm: Rectum, anus and anal canal

187

2.25

5.71

1.6

1.4

64.53

63.15

0.11

153

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

131

837

1.57

5.69

1.5

1.4

59.32

63.21

0.58

108

682

Other benign neoplasms of skin

349

1.89

5.68

1.4

61.21

62.66

0.12

280

Substance abuse, excluding more controls

121

662

1.60

5.67

1.4

49.54

63.60

4.23

109

539

Medicines for HER+ breast cancer

340

1.89

5.66

1.4

72.59

62.45

2.01

277

Disorders of other endocrine glands

537

1.71

5.66

1.5

1.4

61.52

63.97

0.27

445

Other interstitial pulmonary diseases

267

2.03

5.66

1.4

60.31

69.00

0.79

217

Chronic nephritic syndrome

3.73

5.65

1.9

1.3

66.92

58.82

0.33

Intracranial trauma

113

516

1.64

5.65

1.4

58.39

62.41

0.58

426

Diabetic retinopathy, strict definition

233

2.04

5.62

1.4

1.5

57.93

64.16

0.65

193

Other neurological diseases

175

954

1.48

5.61

1.5

1.4

63.20

63.12

0.01

141

781

Interstitial lung disease endpoints

268

2.02

5.60

1.4

60.31

68.91

0.78

218

Interstitial lung disease

268

2.02

5.60

1.4

60.31

68.91

0.78

218

Sequelae of external causes of morbidity and mortality

344

1.89

5.60

1.4

62.54

65.40

0.26

282

Lung diseases due to external agents

262

2.03

5.56

1.5

68.10

67.72

0.03

212

L04AA Selective immunosuppressants

229

2.10

5.52

1.4

46.87

62.70

1.65

190

Chronic periodontitis

210

2.15

5.48

1.4

49.54

63.66

1.56

169

Aortic aneurysm

418

1.79

5.48

1.6

1.4

58.31

65.06

0.96

341

Codeine or tramadol medication

239

945

1.40

5.46

1.3

1.4

63.33

61.32

0.38

194

779

Kidney transplant status

3.48

5.45

1.5

1.4

60.20

53.81

—

Abdominal and pelvic pain

212

742

1.44

5.45

1.4

62.71

61.46

0.19

173

607

Certain disorders involving the immune mechanism

231

2.08

5.41

1.6

1.4

63.05

64.40

0.09

188

Injuries to the abdomen, lower back, lumbar spine and pelvis

550

1.68

5.40

1.4

64.66

65.21

0.05

451

General examination and investigation of persons without complaint and reported diagnosis

156

546

1.52

5.38

1.4

64.10

62.82

0.17

134

460

Symptoms and signs concerning food and fluid intake

112

2.60

5.36

1.3

1.5

52.80

70.11

1.34

Fracture of femur

438

1.73

5.32

1.2

1.5

64.13

66.84

0.28

344

Any mental disorder

240

860

1.40

5.31

1.4

57.98

63.59

1.56

202

706

Other symptoms and signs involving the circulatory and respiratory systems

3.29

5.30

1.3

54.08

61.48

0.27

Open wound of head

123

777

1.56

5.30

1.4

61.02

62.87

0.23

100

628

Pain in limb

161

785

1.48

5.25

1.5

1.4

61.70

62.52

0.10

126

648

Fall on same level

227

905

1.40

5.22

1.4

63.52

61.31

0.42

184

744

Sub-endpoint used in defining T1D endpoints

404

1.78

5.19

1.3

1.4

62.39

64.15

0.18

325

Left bundle-branch block

3.35

5.16

1.2

1.3

85.50

60.02

3.50

Viral infections characterized by skin and mucous membrane lesions

501

1.70

5.14

1.5

1.4

61.38

63.08

0.17

416

Glomerulonephritis

127

2.45

5.11

1.6

1.5

57.09

61.60

0.24

105

Unspecified haematuria

113

612

1.58

5.09

1.4

66.45

62.70

0.55

503

Benign neoplasm: Skin of other and unspecified parts of face

2.73

5.09

1.5

1.3

54.25

63.80

0.58

COPD, hospital admissions 1, only main diagnosis

107

569

1.61

5.08

1.4

62.73

64.82

0.23

460

Injury of other and unspecified intrathoracic organs

2.78

5.04

1.5

61.50

61.85

0.01

Hernia

196

937

1.42

5.04

1.4

62.63

62.56

0.01

156

774

Mental and behavioural disorders due to psychoactive substance use

129

798

1.53

5.03

1.4

51.16

63.31

3.55

116

643

Congenital malformations of the circulatory system

124

2.43

5.00

1.3

1.5

59.80

57.88

0.11

100

Covid-19 suspected case

160

2.25

4.96

1.6

1.5

68.56

60.62

0.86

131

Disorders of thyroid, IBD co-morbidities

100

2.41

4.93

1.6

1.3

59.73

57.54

0.10

Glaucoma

143

844

1.49

4.91

1.4

62.85

64.25

0.18

107

697

Amputation of toe

124

2.44

4.88

1.3

1.6

54.67

67.98

1.32

Basal cell carcinoma

153

831

1.47

4.84

1.4

62.62

65.20

0.40

129

674

Hyperaldosteronism

4.33

4.83

1.2

1.3

64.57

59.45

—

Mental and behavioural disorders due to alcohol

114

717

1.55

4.79

1.4

50.30

63.28

3.52

101

581

Basal cell carcinoma, including avohilmo

155

836

1.46

4.79

1.5

1.4

62.76

64.98

0.34

130

679

Hypokalaemia

150

2.28

4.78

1.5

1.4

57.31

66.92

0.82

123

Other arthritis (FG)

400

1.75

4.77

1.5

1.4

52.03

63.55

1.66

349

Arterial embolism and thrombosis

2.75

4.77

1.5

1.4

64.00

66.21

0.10

Supplementary factors related to causes of morbidity and mortality classified elsewhere

364

1.79

4.74

1.4

67.00

62.96

0.38

303

Asthma, including avohilmo

237

1009

1.37

4.74

1.4

59.53

62.55

0.64

193

826

Concussion

509

1.62

4.70

1.4

60.83

62.33

0.15

423

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

152

2.23

4.70

1.2

1.5

60.93

60.63

0.02

127

Cellulitis

280

1.90

4.66

1.3

1.4

59.11

64.43

0.51

228

ILD, hospital admissions 1, main diag only

232

1.99

4.63

1.4

1.5

62.90

67.36

0.29

190

Other complications of surgical and medical care, not elsewhere classified

2.59

4.63

1.3

1.4

61.25

65.45

0.21

Sensorineural hearing loss

181

897

1.41

4.60

1.4

65.49

62.02

0.70

154

727

Idiopathic gout

166

2.18

4.58

1.4

54.89

66.16

0.64

137

Degeneration of macula and posterior pole

132

730

1.49

4.58

1.3

1.4

67.99

64.73

0.49

600

Malignant neoplasm of digestive organs

110

703

1.54

4.56

1.4

55.57

65.29

1.94

566

Thoracic aortic aneurysm

213

2.03

4.55

1.6

1.3

51.32

65.81

1.87

178

Abnormal findings on diagnostic imaging of other body structures

122

2.38

4.55

1.6

1.4

51.18

62.29

0.81

Accidents

182

641

1.42

4.52

1.4

63.01

63.15

0.02

142

532

Non-Hodgkin lymphoma, all

2.88

4.50

1.7

1.5

58.29

64.28

0.22

Malignant neoplasm of breast, HER-positive

329

1.80

4.49

1.3

72.63

62.20

1.93

272

Falls/tendency to fall

221

806

1.37

4.48

1.4

65.00

61.60

0.72

181

662

Other soft tissue disorders, not elsewhere classified

183

803

1.41

4.48

1.5

1.4

59.27

62.19

0.46

133

664

Congenital malformations, deformations and chromosomal abnormalities

558

1.60

4.48

1.4

58.03

62.22

0.57

469

Abnormal findings on examination of blood, without diagnosis

120

745

1.51

4.47

1.4

60.92

62.89

0.26

602

Decubitus ulcer and pressure area

2.60

4.47

1.2

1.5

58.83

64.60

0.31

Chronic diseases of tonsils and adenoids

631

0.56

4.47

1.4

1.3

59.24

61.11

0.15

526

Hypotension

292

1.86

4.44

1.4

1.5

64.80

68.52

0.33

229

Leisure time condition

202

2.04

4.41

1.5

76.23

64.94

1.18

164

Other ill-defined and unspecified causes of mortality

118

2.39

4.40

1.7

1.5

60.09

66.38

0.36

Conductive and sensorineural hearing loss

184

913

1.40

4.39

1.4

64.96

62.26

0.50

156

742

Other malignant neoplasms of skin (=non-melanoma skin cancer)

148

808

1.45

4.39

1.4

63.02

65.51

0.39

128

653

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

4.27

4.36

1.9

1.3

64.00

61.76

0.07

L02BG Aromatase inhibitors

287

1.85

4.34

1.4

1.3

71.73

61.89

1.59

242

Other antidepressants

222

851

1.36

4.32

1.4

58.29

62.95

1.05

179

696

Acute upper respiratory infections of multiple and unspecified sites

136

695

1.47

4.30

1.3

1.4

54.00

64.05

2.50

112

569

Type of accident

339

1.77

4.29

1.4

69.89

62.69

0.79

280

Sequelae with surgical and medical care as external cause

282

1.85

4.25

1.4

61.45

65.87

0.39

226

Other nutritional deficiencies

108

694

1.52

4.24

1.3

1.4

60.10

61.51

0.16

576

Other diseases of biliary tract

120

2.34

4.24

1.3

1.5

56.95

68.51

0.76

Benign neoplasm: Colon, unspecified

408

1.70

4.22

1.4

63.39

65.26

0.17

340

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

127

2.29

4.19

1.3

1.4

62.30

64.66

0.13

104

Rheumatoid arthritis

441

1.63

4.13

1.4

51.38

64.54

2.11

373

Injury, poisoning and certain other consequences of external causes

113

369

1.54

4.12

1.6

1.4

61.54

64.82

0.40

306

Exclusions for E4_PCOS_BROAD

167

2.10

4.11

1.4

1.5

61.78

62.52

0.04

135

Autoimmune diseases related-to ILD

162

1018

1.40

4.10

1.4

56.60

62.64

1.34

131

839

Pneumocystosis

4.41

4.10

1.4

48.09

59.75

—

Protozoal diseases

3.79

4.09

1.3

1.4

52.66

55.39

0.09

Other spirochaetal diseases

336

0.30

4.06

1.5

1.4

60.30

63.56

—

276

Mental and behavioural disorders due to alcohol, excluding acute intoxication

638

1.54

4.05

1.4

48.52

63.35

3.87

513

Other special examinations and investigations of persons without complaint or reported diagnosis

155

548

1.43

4.05

1.5

1.4

64.19

62.92

0.16

121

462

Injuries to the thorax

103

679

1.52

4.04

1.4

59.11

62.65

0.43

552

Obesity

102

665

1.52

4.02

1.3

1.4

60.60

61.36

0.08

551

All influenza (not pneumonia)

111

2.35

3.98

1.2

1.5

43.21

69.39

2.43

Bronchiectasis

105

2.39

3.98

1.9

1.4

44.79

66.63

1.74

Other external causes of accidental injury

178

641

1.39

3.96

1.4

62.55

63.15

0.07

140

532

Lyme disease

331

0.30

3.96

1.5

1.4

60.30

63.58

—

273

Substance abuse

121

791

1.46

3.95

1.4

49.54

63.44

4.22

109

639

Obesity and other hyperalimentation

102

668

1.51

3.93

1.3

1.4

60.60

61.34

0.08

554

Pneumonitis due to solids and liquids

138

2.18

3.89

1.6

1.5

61.29

66.56

0.29

109

Other (seronegative) rheumatoid arthritis, wide

249

1.85

3.82

1.4

55.47

64.18

0.67

207

Nausea and vomiting

331

1.73

3.82

1.4

66.84

65.39

0.11

273

2.43

3.79

1.6

1.5

61.44

57.43

0.26

Secondary right heart disease

2.75

3.76

1.8

1.4

72.38

61.65

0.58

Obesity due to excess calories

493

1.58

3.72

1.3

1.4

58.40

61.77

0.38

413

Vitreous haemorrhage

141

2.14

3.70

1.2

1.5

54.60

65.69

0.84

114

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

168

2.03

3.66

1.5

1.4

59.04

66.28

0.66

138

Fracture of rib(s), sternum and thoracic spine

464

1.60

3.66

1.3

1.4

57.25

63.51

0.69

388

Tubulo-interstitial nephritis, not specified as acute or chronic

2.61

3.63

1.4

74.92

60.75

1.00

Parodontitis

180

984

1.35

3.59

1.3

1.4

58.50

62.42

0.73

147

808

Parodontitis or operation codes

180

984

1.35

3.58

1.3

1.4

58.50

62.42

0.73

147

808

Ill-defined and unknown causes of mortality

137

2.13

3.55

1.7

1.5

60.63

67.05

0.40

109

Other disorders of ear

189

941

1.34

3.54

1.4

64.17

61.61

0.45

155

769

498

1.53

3.51

1.3

1.4

70.16

66.39

0.46

402

Other disorders of skin and subcutaneous tissue, not elsewhere classified

200

1.91

3.47

1.4

1.5

56.48

64.40

0.61

161

Unknown and unspecified causes of morbidity

2.54

3.46

1.4

1.6

59.46

69.17

0.36

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

133

2.11

3.38

1.4

54.39

64.76

0.58

106

Chronic ulcer of skin, not elsewhere classified

107

2.25

3.38

1.3

1.4

48.94

63.60

0.96

Acute gastritis

101

2.29

3.35

1.5

1.4

50.41

62.78

0.81

Other functional intestinal disorders

628

1.47

3.33

1.5

1.4

62.05

64.96

0.32

521

Viral and other specified intestinal infections

157

1.99

3.33

1.3

1.4

44.95

62.36

1.91

129

Chronic periodontitis, including avohilmo

177

984

1.33

3.28

1.3

1.4

58.52

62.26

0.68

145

809

Zoster [herpes zoster]

255

1.77

3.28

1.4

1.5

63.94

66.87

0.21

207

Early onset COPD

330

1.67

3.27

1.5

1.4

51.79

66.20

2.36

273

Arthropathies

175

662

1.35

3.27

1.5

1.4

61.09

62.61

0.22

136

554

Use of anticholinesterases

591

0.57

3.26

1.2

1.4

61.85

67.60

0.45

471

N06DA Anticholinesterases

591

0.57

3.26

1.2

1.4

61.85

67.60

0.45

471

Fracture of lumbar spine and pelvis

338

1.66

3.24

1.3

1.5

71.84

66.62

0.58

267

COPD-related respiratory insufficiency

213

1.84

3.21

1.6

1.4

63.38

67.67

0.32

166

Statin medication

122

482

1.42

3.20

1.5

1.4

62.94

61.79

0.13

402

Soft tissue disorders

204

809

1.31

3.19

1.4

61.25

62.29

0.15

163

670

L04AX Other immunosuppressants

660

1.46

3.15

1.4

49.47

63.71

2.84

555

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

104

2.22

3.15

1.2

1.4

46.62

63.75

0.99

Delirium, not induced by alcohol and other psychoactive substances

200

1.85

3.14

1.2

1.6

62.62

66.41

0.24

160

Superficial injury of hip and thigh

193

1.87

3.14

1.4

1.6

59.08

63.66

0.31

154

Other mental disorders due to brain damage and dysfunction and to physical disease

179

1.91

3.13

1.3

1.6

57.41

67.10

0.90

149

Unspecified misadventure during surgical and medical care

2.64

3.13

1.6

1.3

58.40

61.48

—

Paracetamol of NSAID medication

114

1.86

3.13

1.4

63.23

60.55

0.16

Other pulmonary heart/vessel disease

2.48

3.13

1.8

1.4

72.38

62.98

0.50

Second line medication for Crohn's disease

678

1.45

3.12

1.4

49.47

63.76

2.88

569

Neurological diseases

169

634

1.34

3.12

1.5

1.4

64.21

62.39

0.27

141

518

Leiomyoma of uterus

133

1.82

3.12

1.3

63.84

54.71

0.87

108

Anxiety (asthma-related co-morbidities)

410

1.52

3.10

1.4

57.32

62.69

0.69

337

Combinations of oral blood glucose lowering drugs

413

1.58

3.10

1.3

1.4

66.35

61.48

0.62

336

Intestinal malabsorption

3.09

1.3

52.14

55.71

—

Cholecystectomy

144

941

1.35

3.08

1.2

1.4

62.38

63.16

0.09

113

773

Ventral hernia

336

1.64

3.08

1.4

65.67

64.91

0.05

287

Chronic periodontitis, complicated

125

2.09

3.08

1.6

1.4

41.48

62.36

1.68

102

Pain (limb, back, neck, head abdominally)

165

616

1.34

3.05

1.5

1.3

64.04

60.54

0.59

133

502

Inguinal hernia

136

669

1.37

3.04

1.5

1.4

59.72

61.71

0.27

107

550

Transient ischemic attack

129

778

1.38

3.03

1.5

1.4

62.82

64.50

0.22

105

640

Other other unspecified disorders of the circulatory system

2.91

3.03

1.6

1.2

74.25

55.48

1.27

Dental operations

163

624

1.34

3.01

1.5

1.4

64.92

62.85

0.33

137

501

371

1.59

3.01

1.4

67.99

67.42

0.04

296

Sulfonylureas

102

569

1.43

3.00

1.4

67.87

63.94

0.63

451

Alcohol use disorder, ICD-based

587

1.47

2.96

1.4

49.52

63.25

3.00

475

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

107

2.16

2.96

1.2

1.4

46.62

64.35

1.04

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

3.16

2.93

1.9

1.3

64.00

60.14

0.13

Acute pancreatitis

287

1.68

2.93

1.3

1.4

56.03

65.77

0.98

238

Dental caries 2 and operation codes, only avohilmo

542

0.63

2.93

1.3

1.4

63.36

60.53

0.29

453

Rheumatoid arthritis, including avohilmo

556

1.48

2.92

1.4

51.76

65.93

2.57

462

Persons encountering health services in circumstances related to reproduction

367

0.54

2.89

1.1

1.4

58.46

55.94

0.14

311

Disorders of the thyroid gland

186

939

1.30

2.84

1.5

1.4

59.82

62.61

0.47

149

769

Colorectal cancer

407

1.55

2.83

1.4

1.5

55.13

67.15

1.62

334

Examination and observation for other reasons

121

532

1.38

2.83

1.4

52.29

63.01

2.45

101

449

Other disorders of glucose regulation and pancreatic internal secretion

103

2.14

2.80

1.5

54.50

62.00

0.35

Sulfasalazine

314

1.63

2.80

1.3

51.64

67.62

1.80

266

Other skin changes

246

1.71

2.78

1.2

1.5

70.16

67.28

0.23

197

Abnormal spermatozoa

239

1.72

2.77

1.4

70.89

66.37

0.37

195

Deviated nasal septum

503

0.54

2.76

1.2

1.4

51.59

61.37

0.69

414

Abnormalities of heart beat

391

1.55

2.73

1.6

1.3

68.92

61.64

0.97

325

Sequelae of cerebrovascular disease

589

1.42

2.72

1.4

64.50

65.16

0.06

481

Other anxiety disorders

322

1.57

2.68

1.4

60.68

60.17

0.04

270

Pyogenic arthritis

2.18

2.67

1.3

1.5

52.75

68.67

0.80

Dental pulpitis 4

213

873

1.27

2.67

1.3

1.4

61.75

62.78

0.16

178

715

Dental pulpitis 1

213

874

1.27

2.65

1.3

1.4

61.75

62.78

0.16

178

715

Intracranial injury

114

808

1.36

2.65

1.4

63.96

62.88

0.12

660

Diseases of pulp and periapical tissues, including avohilmo

213

874

1.27

2.65

1.3

1.4

61.75

62.89

0.18

178

715

Reimbursement for rheumatic diseases

106

768

1.38

2.63

1.4

53.73

63.80

1.95

643

Polyneuropathies and other disorders of the peripheral nervous system

351

1.57

2.63

1.3

1.4

63.83

66.82

0.28

285

Other specified/unspecified arthritis

367

1.56

2.62

1.6

1.4

52.13

63.84

1.52

314

Obesity related asthma

392

1.53

2.59

1.3

1.4

52.37

64.39

1.67

331

Cholecystitis

229

1.71

2.58

1.3

1.5

64.33

68.35

0.26

186

Use of hypnotics and sedatives

207

949

1.26

2.56

1.4

61.00

61.48

0.07

172

776

Chronic pancreatitis

179

1.79

2.51

1.3

1.4

48.08

66.73

2.15

147

Other specified/unspecified hearing loss

122

1.97

2.50

1.2

1.6

66.18

69.07

0.15

103

Open wound of lower leg

172

1.81

2.49

1.3

1.4

55.00

64.53

0.70

137

Benign leiomyoma with endometriosis

2.20

2.47

1.4

1.3

70.25

56.40

0.85

Noninfective enteritis and colitis

585

1.42

2.46

1.3

1.4

52.11

64.09

2.45

490

Low back pain

136

797

1.31

2.43

1.4

56.45

62.45

1.07

111

650

Other and unspecified myopathies

131

1.92

2.40

1.3

1.5

59.10

62.87

0.21

105

Spondylopathies

168

797

1.28

2.39

1.4

59.20

62.76

0.60

142

651

Asthma, hospital admissions , main diagnosis only

146

1011

1.29

2.38

1.4

57.81

62.95

1.03

118

827

Primary open-angle glaucoma

560

1.41

2.34

1.4

62.19

65.58

0.35

458

Malignant melanoma, excluding all cancers (controls excluding all cancers)

161

1.80

2.34

1.6

1.4

59.27

61.96

0.16

131

Malignant neoplasm of stomach, excluding all cancers (controls excluding all cancers)

2.26

2.34

1.4

50.69

61.15

0.54

Degenerative macular diseases

191

1.73

2.33

1.3

1.5

68.94

67.17

0.11

158

Alzheimer disease, including avohilmo

576

0.66

2.31

1.2

1.4

62.23

67.61

0.49

462

Hernia of abdominal wall

661

1.38

2.31

1.4

67.11

62.13

0.73

546

Dental caries 2, only avohilmo

656

0.67

2.30

1.3

1.4

63.36

59.85

0.38

547

Other specified/unspecified soft tissue disorders

2.38

2.29

1.4

49.57

61.15

—

All anxiety disorders

449

1.42

2.29

1.4

57.32

61.33

0.47

372

Injuries to the elbow and forearm

118

806

1.32

2.29

1.3

1.4

57.03

63.21

1.10

669

Ulcer of oesophagus

113

1.95

2.25

1.5

1.4

64.50

65.88

0.08

Nonischemic cardiomyopathy

2.28

2.24

1.1

1.4

52.50

59.58

—

Parodontitis or/and operation codes

107

471

1.35

2.24

1.3

1.4

59.30

62.26

0.36

394

Seronegative rheumatoid arthritis

135

1.86

2.21

1.4

50.83

66.44

0.89

119

Symptoms and signs involving cognition, perception, emotional state and behaviour

181

1014

1.25

2.21

1.4

64.26

62.12

0.36

147

826

Primary open-angle glaucoma, strict

456

1.45

2.21

1.4

63.71

65.78

0.16

375

Multiple myeloma and malignant plasma cell neoplasms

2.63

2.18

1.5

1.4

63.17

59.34

—

Multiple myeloma, excluding all cancers (controls excluding all cancers)

2.63

2.18

1.5

1.4

63.17

59.34

—

Tobacco use

2.51

2.18

1.2

1.3

57.08

57.27

0.01

Other reaction to severe stress, and adjustment disorders

280

1.57

2.18

1.4

59.86

60.26

0.02

236

Acute pancreatitis (for exclusion)

312

1.54

2.18

1.3

1.4

56.03

64.95

0.87

258

Other gastritis (incl. Duodenitis)

328

1.53

2.18

1.5

1.4

58.15

63.49

0.51

280

Other chondrocalcinosis

3.73

2.16

1.3

1.4

38.57

63.08

—

Duodenal ulcer

196

1.69

2.15

1.4

60.08

66.85

0.41

161

Thyrotoxicosis, other and/or unspecified

196

1.69

2.14

1.6

1.4

70.20

62.45

0.56

163

Hypothyroidism, strict autoimmune

134

686

1.29

2.13

1.5

1.3

61.54

63.71

0.28

105

562

Dental caries 2

670

0.69

2.12

1.3

1.4

64.55

59.64

0.62

557

Dorsalgia

188

818

1.25

2.12

1.4

61.23

62.50

0.18

154

667

Other hearing loss

486

1.42

2.11

1.3

1.4

69.21

64.15

0.63

391

Seropositive rheumatoid arthritis

370

1.48

2.11

1.3

1.4

49.82

66.56

2.31

320

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

371

1.48

2.11

1.3

1.4

49.82

66.10

2.20

304

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

152

1.78

2.11

1.5

1.4

56.55

65.54

0.61

125

Seropositive rheumatoid arthritis, strict definition

182

1.71

2.10

1.3

1.5

45.67

64.48

1.75

149

Right hemicolectomy

2.01

2.10

1.3

1.4

64.77

64.16

0.02

Malignant neoplasm of kidney, except renal pelvis

153

1.77

2.07

1.4

1.5

61.41

66.56

0.32

121

Osteomyelitis

2.03

2.05

1.4

1.5

49.33

67.72

1.44

Other noninfective gastroenteritis and colitis

301

1.53

2.03

1.2

1.5

53.74

64.91

1.39

249

Alzheimer’s disease, wide definition

454

0.62

2.02

1.4

1.5

55.83

67.72

0.96

362

Other and specified injuries of hip and thigh

3.10

2.01

1.7

1.3

83.97

57.50

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

2.01

2.00

1.4

56.23

61.56

0.21

Headache

551

1.35

2.00

1.4

65.77

64.23

0.17

468

Glaucoma suspect

561

1.37

1.97

1.4

64.38

65.51

0.10

471

Sleep disorders (combined)

180

956

1.23

1.97

1.4

59.94

62.15

0.34

144

785

Appendectomy

715

1.32

1.94

1.4

65.75

60.77

0.92

598

Nontoxic multinodular goitre

265

1.55

1.94

1.2

1.4

63.98

64.53

0.03

214

Myocardial infarction, with ST-elevation

354

1.47

1.94

1.6

1.4

60.29

66.87

0.75

283

Pain, not elsewhere classified

273

1.54

1.93

1.5

1.4

61.78

66.13

0.34

236

Alzheimer’s disease (Late onset)

428

0.62

1.93

1.4

1.5

53.31

67.69

1.16

337

Diseases of the myoneural junction and muscle

172

1.69

1.92

1.3

1.4

58.59

63.03

0.26

136

Methotrexate

150

1.74

1.90

1.2

1.4

43.95

68.56

2.29

126

Unstable angina pectoris

573

1.33

1.90

1.5

1.4

57.52

63.90

0.92

471

Dorsopathies

196

818

1.22

1.90

1.5

1.4

58.94

62.50

0.70

170

667

Parodontitis and operation codes

156

975

1.24

1.89

1.3

1.4

57.66

62.63

0.93

129

800

Persons encountering health services for examination and investigation

139

548

1.27

1.89

1.5

1.4

61.69

62.92

0.15

110

462

Malignant neoplasm of colon

259

1.55

1.89

1.3

1.5

56.66

66.96

0.99

207

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

136

1.77

1.86

1.5

1.4

56.50

63.94

0.46

111

Other diseases of oesophagus

151

1.73

1.86

1.3

1.4

69.12

64.34

0.25

125

Pain in thoracic spine

151

1.72

1.86

1.2

1.4

63.81

69.23

0.36

121

Speech therapy

374

1.45

1.85

1.7

1.4

66.95

64.78

0.21

304

Dental pulpitis 2

159

653

1.25

1.85

1.4

65.15

63.40

0.25

133

524

Hypoglycaemia, other or unspecified

2.03

1.85

1.3

53.00

60.27

—

Disorders of vitreous body and globe

722

1.31

1.84

1.2

1.4

58.53

64.12

0.82

597

Use of biperiden

2.21

1.84

1.1

1.2

64.00

57.57

0.24

Pyoderma

3.55

1.84

1.3

1.4

28.83

46.82

—

Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours

4.21

1.83

1.8

1.3

75.20

68.29

—

Colectomy operation

270

1.52

1.81

1.3

1.5

57.47

66.91

0.90

216

Operations for atrial fibrillation

3.07

1.80

1.9

1.3

44.43

59.19

—

Benign neoplasm: Sigmoid colon

295

1.49

1.79

1.5

1.4

52.75

66.56

1.60

237

Dental caries 2 and operation codes

653

0.72

1.78

1.3

1.4

64.55

59.83

0.58

544

Exposure to unspecified factor

168

1065

1.22

1.78

1.4

59.03

62.32

0.55

131

879

Thyrotoxicosis

263

1.52

1.78

1.6

1.4

70.06

62.36

0.69

221

Other/unspecified seropositive rheumatoid arthritis

386

1.43

1.77

1.3

1.4

49.82

66.29

2.25

318

Unspecific neurodegenerative disorder

623

0.73

1.77

1.2

1.4

59.64

67.05

0.82

506

Continuous positive airway pressure

106

1.79

1.76

1.4

1.3

75.42

61.43

1.30

Malignant neoplasm of urinary organs

177

1.64

1.75

1.4

1.5

61.84

66.52

0.32

140

Hyperplasia of prostate

101

441

1.31

1.75

1.5

1.4

64.97

62.54

0.28

356

Use of other anti-dementia drugs

497

0.66

1.75

1.3

1.4

53.88

68.64

1.44

396

Use of memantine

497

0.66

1.75

1.3

1.4

53.88

68.64

1.44

396

Intestinal adhesions without obstruction

117

1.80

1.74

1.3

1.5

66.53

67.63

0.05

Other obstructive and reflux uropathy

2.51

1.74

1.3

1.2

60.00

62.76

—

Other/unspecified rheumatoid arthritis

170

1.65

1.73

1.4

1.5

62.63

66.53

0.22

134

Respiratory conditions due to other external agents

2.69

1.73

1.3

80.75

63.79

—

Hyperparathyroidism

238

1.54

1.72

1.8

1.5

60.34

66.79

0.53

191

In situ neoplasms

551

1.34

1.70

1.5

1.4

63.76

65.22

0.14

452

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

192

1.60

1.70

1.3

1.5

48.77

61.64

1.09

157

Lower back pain or/and sciatica

184

1057

1.21

1.69

1.4

58.07

62.51

0.89

154

860

Seropositive rheumatoid arthritis, wide

390

1.41

1.69

1.3

1.4

49.82

66.30

2.25

322

Sarcoidosis

156

1.67

1.68

1.4

69.75

62.72

0.42

129

Alzheimer disease

524

0.70

1.66

1.3

1.4

62.17

67.85

0.46

417

Actinic keratosis

698

1.29

1.66

1.5

1.4

58.42

66.37

1.30

557

Insulin, fast-acting (human)

149

1.68

1.66

1.1

1.4

49.65

62.60

0.97

119

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

282

1.39

1.66

1.4

63.16

65.40

0.20

222

Coxarthrosis

112

597

1.27

1.66

1.4

64.19

63.33

0.09

499

Dislocation, sprain and strain of joints and ligaments of knee

611

0.70

1.66

1.4

64.61

60.57

0.37

511

ILD medications: azathioprine

134

1.72

1.65

1.1

1.3

47.27

64.30

1.20

111

Essential (haemorrhagic) thrombocythaemia

2.81

1.65

1.3

1.4

61.71

44.05

—

Dental caries 1

174

732

1.22

1.63

1.4

64.81

63.24

0.24

145

592

Diseases of oral cavity, salivary glands and jaws

185

786

1.21

1.63

1.4

61.89

63.14

0.18

151

645

Other and unspecified polyneuropathies, also in other diseases

318

1.45

1.63

1.3

1.4

65.27

67.20

0.15

257

Benign neoplasm of other and unspecified endocrine glands

158

1.65

1.62

1.5

64.05

64.47

0.02

128

Phlebitis and thrombophlebitis (not including DVT)

294

1.46

1.61

1.5

1.4

66.17

63.55

0.18

248

Other viral diseases

261

1.49

1.60

1.5

1.4

57.15

61.62

0.33

218

Coxarthrosis [arthrosis of hip](FG)

118

680

1.26

1.59

1.4

65.00

63.85

0.13

567

Other aneurysm

1.95

1.59

1.3

1.5

52.90

64.85

—

Other crystal arthropathies

2.71

1.58

1.3

1.5

38.57

65.62

—

Benign neoplasm of other and ill-defined parts of digestive system

247

1.50

1.57

1.2

1.5

53.66

65.19

0.95

202

Dental caries, including avohilmo

173

732

1.21

1.55

1.4

64.56

63.30

0.18

144

591

Schizophrenia or delusion, excluding more controls

286

1.46

1.55

1.3

1.4

57.33

63.16

0.47

236

Exclusions for E4_PCOS_CONSORTIUM

440

1.30

1.55

1.4

61.43

62.02

0.06

366

Colorectal adenocarcinoma

355

1.41

1.55

1.3

1.5

56.00

66.97

1.17

288

Benign neoplasm: Skin of other and unspecified parts of face

153

1.64

1.53

1.5

54.25

65.94

0.81

121

Infection of intervertebral disc (pyogenic)

3.36

1.52

1.8

1.5

69.40

89.70

—

Maltreatment syndromes

2.60

1.51

1.3

1.4

35.57

58.36

—

Degenerative diseases of the nervous system

574

0.73

1.51

1.2

1.4

59.31

67.53

0.79

460

Caught, crushed, jammed or pinched in or between objects

0.00

1.51

0.0

1.4

—

59.62

—

Disorders of sclera, cornea, iris and ciliary body

703

1.28

1.50

1.2

1.4

56.29

62.85

0.85

584

Disorders of skin appendages

502

1.33

1.50

1.4

58.75

63.30

0.45

425

Sleep apnoea

166

936

1.20

1.50

1.4

60.11

61.82

0.23

131

776

Anxiety disorders, excluding more controls

124

663

1.24

1.50

1.3

1.4

59.74

63.41

0.58

101

547

Non-selective monoamine reuptake inhibitors

538

1.32

1.49

1.3

1.4

57.61

64.72

1.00

444

Skin changes due to chronic exposure to nonionizing radiation

708

1.27

1.48

1.5

1.4

58.42

66.51

1.34

567

Fenamates

174

0.54

1.48

1.9

1.5

63.64

66.04

0.11

141

Dental caries 3

177

755

1.20

1.48

1.4

63.92

63.50

0.06

147

611

Azathioprine

139

1.66

1.48

1.1

1.4

47.27

64.27

1.20

113

Crohn disease

124

1.70

1.46

1.3

1.5

53.69

60.60

0.35

102

Gastro-oesophageal reflux disease

118

846

1.24

1.45

1.5

1.3

60.67

62.05

0.16

710

Hyperfunction of pituitary gland

2.51

1.45

1.4

1.2

74.43

56.22

—

Acute upper respiratory infections

190

1005

1.18

1.45

1.4

55.63

63.70

2.29

155

820

Symptoms and signs involving the skin and subcutaneous tissue

116

935

1.24

1.44

1.3

1.4

56.97

63.04

1.11

101

756

Lichen simplex chronicus

2.32

1.43

1.3

1.2

75.67

58.79

—

Dermatophytosis

188

1.55

1.42

1.2

1.5

50.64

65.84

1.13

155

Macular pucker

229

1.49

1.41

1.2

1.4

61.95

68.01

0.40

187

Disorders of vitreous body

706

1.26

1.38

1.2

1.4

58.76

64.30

0.81

587

Familial hypercholesterolemia, with ischemic heart disease

166

1.57

1.37

2.0

1.3

60.38

66.30

0.43

137

Carcinoma in situ of cervix uteri

2.61

1.36

1.0

1.4

50.83

45.11

—

Melanocytic naevi of lower limb, including hip

0.00

1.34

0.0

1.2

—

56.75

—

Disorders of lacrimal system

575

1.29

1.32

1.3

1.4

63.76

64.19

0.03

477

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

279

1.33

1.32

1.4

65.06

65.43

0.03

219

Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

113

1.68

1.30

1.3

1.5

61.23

68.62

0.30

Hypothermia

2.51

1.30

1.3

1.4

37.17

59.73

—

Benign neoplasm of urinary organs

2.36

1.29

2.0

1.4

66.38

56.00

—

Kela-code for severe mental illness

412

1.34

1.28

1.3

1.4

56.73

60.81

0.39

343

736

1.24

1.28

1.5

1.4

58.97

66.41

1.21

588

Inflammatory bowel disease

361

1.36

1.27

1.3

1.4

45.70

63.42

3.01

300

Vascular syndromes of brain in cerebrovascular disorders

1.79

1.27

1.2

1.5

54.40

66.11

—

Isolated proteinuria

2.30

1.27

1.4

1.3

67.87

60.87

—

Pustulosis palmaris et plantaris

2.29

1.27

1.0

1.2

58.75

59.26

—

Herpesviral [herpes simplex] infections

130

1.62

1.26

1.6

1.5

53.81

62.15

0.48

110

Other dorsopathies, not elsewhere classified

182

818

1.17

1.26

1.5

1.4

58.20

62.50

0.85

152

667

Nontoxic goitre/thyroid nodule

397

1.34

1.24

1.2

1.4

61.03

64.21

0.27

324

Hypothyroidism, other/unspecified

156

870

1.18

1.24

1.5

1.4

60.16

62.98

0.43

126

710

Hypothyroidism, strict autoimmune, 3 medication purchases required

145

831

1.19

1.23

1.4

61.57

63.14

0.21

117

678

Myelodysplastic syndrome

2.66

1.22

1.8

1.4

54.40

70.75

—

Fracture of forearm

645

1.25

1.22

1.3

1.4

55.62

64.14

1.25

542

Benign neoplasm: Oesophagus

2.65

1.22

1.2

1.4

23.80

70.45

—

Disorders of parathyroid gland

284

1.39

1.21

1.7

1.5

59.37

66.68

0.66

233

TMD related operations

141

0.50

1.20

1.3

1.5

45.57

59.15

—

121

Epilepsy

442

1.31

1.20

1.3

1.4

60.89

62.61

0.14

367

Retinal vascular disorders

205

1.47

1.19

1.5

57.95

68.68

0.72

167

Organic, including symptomatic, mental disorders

120

719

1.21

1.18

1.3

1.4

60.47

65.82

0.84

588

Gonarthrosis,primary

135

1008

0.84

1.18

1.4

60.36

62.55

0.29

109

821

Hemiplegia

1.88

1.18

1.3

72.00

60.71

0.60

Visual disturbances and blindness

711

1.24

1.17

1.4

63.96

63.50

0.04

591

Use of antiglaucoma preparations and miotics

125

1.60

1.17

1.3

1.6

62.31

68.03

0.36

Wet age-related macular degeneration

318

1.36

1.17

1.3

1.5

75.79

67.53

1.00

251

Injury of muscle and tendon at shoulder and upper arm level

556

0.74

1.16

1.3

1.4

59.40

61.93

0.19

457

Circumscribed brain atrophy

0.00

1.16

0.0

1.3

—

63.52

—

Sleep apnoea, including avohilmo

170

945

1.17

1.16

1.4

61.01

61.95

0.12

133

784

Other specific joint derangements/joint disorders

623

0.80

1.15

1.4

56.33

61.80

0.62

524

Oter anti-inflammatory and antirheumatic agents, non-steroids

274

1.30

1.14

1.7

1.5

65.83

66.14

0.02

220

Pain in joint

541

0.78

1.14

1.4

1.3

54.29

59.93

0.61

446

Weight loss

126

1.59

1.14

1.3

1.5

53.33

66.90

0.63

Unspecified mental disorder

456

1.29

1.13

1.3

1.4

57.08

61.27

0.42

381

Schizophrenia, schizotypal and delusional disorders

326

1.35

1.13

1.3

1.4

57.11

60.48

0.25

271

Palmar fascial fibromatosis [Dupuytren]

309

1.36

1.13

1.5

1.4

66.21

66.41

0.01

254

Unspecified fall

710

1.23

1.12

1.3

1.4

59.82

63.68

0.44

586

Retinal vascular occlusion

200

1.45

1.11

1.5

57.95

68.03

0.66

162

Episodal and paroxysmal disorders

196

871

1.15

1.11

1.4

62.35

0.00

158

714

Dental pulpitis 2, only avohilmo

155

676

1.17

1.10

1.4

63.91

63.36

0.07

131

541

Dental operations, only avohilmo

158

691

1.17

1.10

1.5

1.4

61.60

63.23

0.23

131

558

Systemic lupus erythematosus, unspecified

2.39

1.09

1.4

1.2

31.20

53.20

—

Use of donepezil

395

0.70

1.09

1.1

1.5

63.57

67.17

0.20

305

Dizziness and giddiness

138

952

1.18

1.09

1.4

67.39

62.73

0.94

114

780

Nerve, nerve root and plexus disorders

192

1049

1.15

1.09

1.4

60.73

62.56

0.29

159

854

Osteoporosis with pathological fracture (FG)

1.76

1.06

1.1

1.3

59.00

66.53

—

Injuries to the neck

236

1.40

1.06

1.4

54.16

63.96

0.69

195

Mood disorders, excluding more controls

152

792

1.17

1.06

1.4

57.05

62.79

1.17

128

647

Myocardial infarction, unclassifiable

451

1.27

1.05

1.4

56.71

65.98

1.29

357

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

383

1.31

1.05

1.4

58.22

63.87

0.48

321

Dental caries 1 and operation codes, only avohilmo

207

0.70

1.04

1.5

1.4

64.21

61.67

0.14

178

Depression or dysthymia

128

605

1.18

1.04

1.6

1.4

60.09

63.53

0.52

110

495

Malignant neoplasm of breast, HER-negative

195

1.44

1.03

1.4

1.3

56.61

61.24

0.30

160

Motorcycle rider injured in other and unspecified transport accidents

1.96

1.03

1.3

56.67

51.38

—

Papulosquamous disorders

517

1.26

1.03

1.5

1.4

64.60

63.33

0.11

436

Abnormal weight loss

114

1.58

1.02

1.3

1.5

54.73

67.49

0.52

Dental caries 1, only avohilmo

172

762

1.15

1.01

1.4

62.89

63.03

0.02

141

618

Olecranon bursitis

1.65

1.00

1.8

1.4

56.00

67.89

—

Spontaneous abortion

228

0.69

1.00

1.2

1.3

56.99

59.82

0.13

199

Other diseases of upper respiratory tract

170

1017

0.87

0.98

1.5

1.4

62.31

62.76

0.06

139

826

Disorder of lipoprotein metabolism, unspecified

206

1.41

0.98

1.1

1.4

57.82

65.61

0.52

167

Laparoscopic left hemicolectomy

2.18

0.98

1.0

1.4

63.00

56.50

—

Benign neoplasm: Rectum

292

1.34

0.97

1.6

1.4

64.63

66.75

0.18

236

Spondylosis

102

734

1.19

0.97

1.4

55.60

62.61

1.12

597

Acute alcohol intoxication ICD-9

1.86

0.96

1.0

1.3

67.40

63.85

—

Malignant neoplasm of rectum

165

1.46

0.96

1.4

53.86

68.16

0.74

131

Mandibular retrognathia

0.00

0.96

0.0

1.3

—

52.69

—

Fitting and adjustment of other devices

477

1.25

0.96

1.2

1.3

68.66

64.94

0.38

384

5-aminosalicylic acid

207

1.40

0.96

1.3

1.4

40.82

66.65

3.39

172

Other maternal disorders predominantly related to pregnancy

253

0.72

0.95

1.3

54.36

61.17

0.44

217

Neurotic, stress-related and somatoform disorders

124

752

1.17

0.95

1.3

1.4

59.22

61.30

0.28

101

626

Hypothyreosis and Thyroxine purchase for inclusion criteria

159

912

1.15

0.95

1.5

1.4

60.56

63.02

0.37

129

745

Fissure and fistula of anal and rectal regions

311

1.32

0.94

1.5

1.4

59.11

65.03

0.51

268

Varicose veins of other sites

1.72

0.92

1.2

1.6

67.67

56.74

0.53

Gingivitis and periodontal diseases

170

767

1.14

0.91

1.3

1.4

57.40

62.91

1.11

134

630

Conjunctivitis

763

0.82

0.90

1.4

53.07

63.18

1.57

630

Disorders of eyelid, lacrimal system and orbit

151

1032

1.15

0.90

1.3

1.4

66.18

62.45

0.65

118

846

Traumatic subdural haemorrhage

223

1.37

0.90

1.5

1.4

68.08

65.35

0.18

178

Dental pulpitis 4, only avohilmo

200

924

1.13

0.90

1.3

1.4

60.59

62.76

0.37

164

755

Colon adenocarcinoma

210

1.38

0.90

1.3

1.5

62.30

66.82

0.28

167

Disorders of synovium and tendon

629

0.80

0.90

1.4

56.48

62.41

0.58

523

Spirochaetal infections, other/unspecified

101

0.49

0.89

1.0

1.4

40.00

60.30

—

Carcinoma in situ of breast, intraductal

2.07

0.89

1.2

1.3

57.33

52.33

—

Injuries to the ankle and foot

671

1.19

0.88

1.3

1.4

53.09

61.92

1.40

564

Alcohol dependence

403

1.27

0.88

1.4

49.78

66.00

2.54

325

Anomalies of dental arch relationship, including avohilmo

117

0.54

0.88

1.9

1.5

45.86

58.13

—

100

Glaucoma, exfoliation

177

1.41

0.88

1.4

1.6

57.56

67.48

0.84

143

Benign neoplasm: Rectum, anus and anal canal

324

1.30

0.87

1.6

1.4

64.53

66.83

0.21

265

Acute myeloid leukaemia and myelodysplastic syndromes

2.01

0.87

2.2

1.4

55.67

68.11

—

Viral pneumonia (known virus, not influenza)

2.01

0.87

1.3

1.4

52.17

57.06

—

Anxiety disorders

126

771

1.16

0.86

1.3

1.4

59.41

61.60

0.30

102

639

Other diseases of urinary system

183

912

1.13

0.84

1.4

63.04

62.37

0.09

140

757

Acute appendicitis, with complications

274

1.32

0.83

1.8

1.5

63.69

64.71

0.07

229

DVT of lower extremities

283

1.31

0.83

1.4

60.58

66.13

0.40

234

Dental pulpitis 1, only avohilmo

199

926

1.12

0.82

1.3

1.4

60.91

62.79

0.31

163

756

Intermittent heterotropia

1.88

0.81

1.3

67.83

55.23

—

Poor fetal growth

1.88

0.81

1.2

1.5

30.83

62.56

—

Infections with a predominantly sexual mode of transmission

197

1.37

0.81

1.3

1.4

60.10

57.10

0.16

165

Visual disturbances

645

1.19

0.80

1.4

63.57

62.96

0.05

534

Schizophrenia or delusion

329

1.28

0.80

1.3

1.4

57.33

60.59

0.23

272

Oral leukoplakia

0.00

0.79

0.0

1.3

—

65.75

—

Orthopaedic devices associated with adverse incidents

0.00

0.79

0.0

1.3

—

59.41

—

Rubella [German measles]

1.82

0.79

1.7

1.3

69.00

47.15

—

Acute posthaemorrhagic anaemia

1.67

0.78

1.3

49.00

62.32

—

Paralytic ileus

1.67

0.78

1.9

1.4

62.13

66.89

—

Primary gonarthrosis, bilateral

799

0.84

0.78

1.4

62.85

63.57

0.06

651

Melanocytic naevi

199

1.36

0.77

1.5

1.4

66.76

57.75

0.76

170

Bitten or stung by nonvenomous insect and other nonvenomous arthropods

0.00

0.77

0.0

1.2

—

57.95

—

Dental caries 1 and operation codes

174

793

1.13

0.77

1.4

62.32

62.49

0.02

144

646

Benign lipomatous neoplasm

417

0.77

1.3

1.4

66.65

63.59

0.21

349

Systemic connective tissue disorders

493

1.22

0.77

1.3

1.4

62.19

66.60

0.43

407

Other benign neoplasms of skin

558

1.20

0.75

1.4

61.21

63.94

0.26

461

Other disorders of lacrimal gland

440

1.23

0.75

1.2

1.4

57.35

63.50

0.54

359

SLE, strict definition

2.09

0.74

1.4

1.2

31.20

55.44

—

SLE, ICD10

2.09

0.74

1.4

1.2

31.20

55.44

—

Other viral diseases, not elsewhere classified

183

1.36

0.74

1.6

1.5

56.15

61.57

0.31

150

Acute appendicitis, no complications

634

0.82

0.74

1.4

60.74

61.77

0.08

532

Dental caries 3 and operation codes, only avohilmo

227

0.77

0.74

1.5

1.4

57.27

62.27

0.34

193

Other misadventures during surgical and medical care

2.01

0.72

3.4

1.3

72.40

60.33

—

Benign neoplasm: Connective and other soft tissue of lower limb, including hip

2.01

0.72

1.2

1.3

67.40

56.24

—

Dermatitis and eczema

181

1064

1.12

0.72

1.4

59.57

62.37

0.50

151

868

Acetic acid derivatives and related substances

280

1.21

0.72

1.5

58.76

65.96

0.72

225

Disorders of continuity of bone

1.58

0.71

1.8

1.5

56.86

59.89

—

Follow-up examination after treatment for conditions other than malignant neoplasms

409

0.82

0.71

1.3

1.4

51.69

64.37

1.48

347

Polyuria

333

0.75

0.71

1.3

1.4

51.30

65.83

1.06

277

Cluster headache, strict, including avohilmo

1.75

0.71

1.6

1.3

57.43

54.64

—

Other/unspecified dorsalgia

523

1.20

0.70

1.5

1.4

64.72

64.45

0.02

431

Acute bronchiolitis

1.87

0.69

1.2

1.3

57.80

62.73

—

Injuries to the wrist and hand

125

1025

0.88

0.69

1.4

55.78

61.87

1.06

843

Migraine

358

0.78

0.68

1.4

1.3

57.78

61.74

0.27

299

Paraplegia, diplegia of upper limbs

1.86

0.68

1.0

1.3

55.00

61.88

—

Dementia in Alzheimer disease

331

0.77

0.68

1.3

1.6

50.67

68.39

1.21

264

Systemic lupus erythematosus

1.85

0.68

1.4

1.2

31.20

57.67

—

Keratitis

446

1.21

0.68

1.2

1.4

55.28

62.40

0.66

375

Coxarthrosis, primary, with hip surgery

808

1.15

0.67

1.4

65.82

64.03

0.21

657

Other diseases of anus and rectum

441

0.79

0.67

1.3

1.4

69.41

65.29

0.33

366

Other and unspecified vascular occlusions

153

1.37

0.67

1.4

1.6

60.33

68.18

0.38

123

Coxarthrosis, primary

121

929

1.13

0.65

1.4

66.43

63.39

0.48

757

Other disorders of urethra and urinary system

119

787

1.13

0.65

1.4

63.95

64.23

0.03

650

Other diseases of jaws

1.54

0.65

1.3

1.6

45.40

60.75

—

Congenital malformations of eye, ear, face and neck

1.59

0.65

1.3

1.2

41.43

58.21

—

Dementia

619

0.86

0.64

1.3

1.4

58.55

67.11

1.11

501

Alzheimer’s disease (Late onset), excluding more controls

219

0.76

0.64

1.4

1.5

58.87

68.03

0.54

175

Disorders of conjunctiva

865

0.87

0.64

1.5

1.4

53.51

63.13

1.70

718

Carcinoma in situ of skin of trunk

1.73

0.64

1.2

67.40

61.75

—

Transient global amnesia

129

0.62

0.63

1.3

1.5

71.50

65.26

—

103

Acute sinusitis

505

1.18

0.63

1.4

51.50

63.96

1.96

422

Diaphragmatic hernia

552

1.18

0.62

1.4

55.72

65.00

1.13

457

Glucosamine medication

101

707

1.14

0.62

1.5

1.4

64.67

65.39

0.07

575

Medical observation and evaluation for suspected diseases and conditions

121

548

1.13

0.62

1.4

54.55

62.92

1.72

462

Multiple myeloma and malignant plasma cell neoplasms

1.55

0.62

1.5

1.4

63.17

65.12

—

Spinal stenosis

105

724

1.14

0.62

1.3

1.4

62.99

63.97

0.10

588

Nontoxic single thyroid nodule

1.55

0.62

1.4

1.5

63.27

65.79

0.09

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

1.63

0.62

1.3

1.4

70.75

52.98

—

Ulcerative colitis

288

1.25

0.62

1.3

1.4

38.32

64.82

4.97

235

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

1.67

0.61

1.4

1.2

42.40

43.52

—

Dental caries 3, only avohilmo

170

785

1.11

0.61

1.4

62.28

63.29

0.14

140

637

Mental and behavioural disorders due to sedatives or hypnotics

1.60

0.61

1.4

1.3

37.75

57.40

—

Brain glioblastoma and astrocytoma

0.00

0.60

0.0

1.3

—

62.31

—

Need for immunization against other single viral diseases

0.00

0.60

0.0

1.5

—

57.50

—

Adenocarcinoma and papilloma adenocarcinoma of rectum

165

1.34

0.60

1.2

1.4

43.92

67.81

1.48

131

Lagophthalmos

0.00

0.60

0.0

1.5

—

62.17

—

Dental caries 3 and operation codes

174

809

1.10

0.59

1.5

1.4

61.00

62.65

0.24

144

658

Chondromalacia

0.00

0.59

0.0

1.4

—

51.60

—

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

1.54

0.59

1.6

1.3

48.90

55.84

—

Fracture of lower leg, including ankle

748

1.15

0.59

1.3

1.4

62.77

62.86

0.01

620

Medical treatment for female infertility

1.56

0.58

1.6

1.5

65.20

61.50

—

Other blood glucose lowering drugs, excl. Insulins

255

1.26

0.58

1.4

66.41

64.51

0.11

201

Other and unspecified effects of external causes

255

1.26

0.57

1.4

41.42

63.95

2.47

213

Internal derangement of knee

510

1.17

0.57

1.4

65.20

62.00

0.30

432

Fibroblastic disorders

401

1.20

0.57

1.5

1.4

66.59

64.69

0.13

332

Any dementia

593

0.87

0.56

1.3

1.4

60.15

67.56

0.79

485

Anterior Iridocyclitis

256

1.25

0.56

1.1

1.4

58.00

64.28

0.41

207

Umbilical hernia

365

1.21

0.56

1.3

1.4

63.94

62.79

0.08

304

Melanocytic naevi

341

0.79

0.55

1.5

1.4

66.76

64.69

0.13

279

Retinal detachments and breaks

569

1.16

0.55

1.3

1.4

68.38

63.56

0.57

472

Spondyloarthritis

239

1.26

0.55

1.5

1.4

55.09

65.82

0.78

198

Malignant neoplasm of prostate

604

0.88

0.54

1.4

67.45

62.98

0.63

488

Diseases of male genital organs

108

485

1.13

0.54

1.5

1.4

66.38

60.65

0.88

393

Hydrocele

231

1.26

0.53

1.3

1.4

62.00

65.48

0.21

191

Gonarthrosis, primary, with knee surgery

847

0.89

0.53

1.4

60.15

63.62

0.39

691

Diplopia

178

1.29

0.52

1.3

1.5

67.00

64.86

0.11

145

Colonic or urogenital fistula

368

1.20

0.52

1.5

1.4

59.24

64.16

0.41

307

Diseases of the ear and mastoid process

192

892

1.09

0.52

1.3

1.4

66.20

60.81

1.28

152

732

Other arthrosis

590

0.87

0.52

1.3

1.4

61.26

62.52

0.11

497

Suggestive for eosinophilic asthma

117

1.37

0.52

1.2

1.6

51.09

62.91

0.57

Alzheimer’s disease, wide definition, excluding more controls

230

0.80

0.51

1.3

1.5

59.71

67.66

0.48

185

Inguinal hernia, bilateral

197

1.27

0.51

1.6

1.4

72.17

67.40

0.31

166

Irritable bowel syndrome

303

0.79

0.50

1.4

57.83

64.63

0.41

254

Recurring oral aphthae, including avohilmo

144

1.32

0.50

1.2

1.5

58.34

64.33

0.28

114

Atopic dermatitis

426

0.84

0.50

1.5

1.4

55.24

61.41

0.54

356

Presbycusis

269

1.22

0.49

1.2

1.5

70.54

68.07

0.16

211

Cluster headache, wide,, including avohilmo

1.56

0.49

1.6

1.3

57.43

54.97

—

Nasal polyp

312

0.80

0.48

1.2

1.4

60.70

63.86

0.16

258

Missing teeth due to accident, extraction or parodontitis

154

1.30

0.48

1.5

48.54

64.08

1.07

118

Oral leukoplakia and related diseases, including avohilmo

110

0.64

0.48

1.1

1.6

50.43

62.00

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

172

1.28

0.48

1.2

1.4

43.92

67.87

1.49

135

malignant neoplasm of male genital organs

607

0.89

0.47

1.4

65.59

63.12

0.29

490

Dementia, including avohilmo

666

0.89

0.47

1.3

1.4

60.40

66.74

0.87

542

Urticaria

300

0.80

0.47

1.7

1.4

46.42

61.71

1.08

250

Postmenopausal bleeding

184

0.81

0.47

1.4

1.3

65.33

63.57

0.10

154

Other disorders of veins

504

1.15

0.46

1.5

1.4

59.87

64.14

0.42

426

Benign lipomatous neoplasm

264

1.21

0.45

1.3

1.4

66.65

59.99

0.53

216

Myopia

0.59

0.45

1.6

1.5

69.80

58.30

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

496

1.14

0.45

1.4

66.51

63.50

0.31

418

Complications of labour and delivery

270

0.85

0.44

1.2

1.3

51.66

62.79

1.05

235

Soft tissue disorders related to use, overuse and pressure

366

1.18

0.44

1.5

1.4

59.36

64.18

0.30

309

Atopic dermatitis, strict definition with reimbursement

195

1.24

0.44

1.5

1.4

50.85

57.90

0.43

166

Other joint disorders

136

662

1.09

0.44

1.4

59.49

62.61

0.44

108

554

Antenatal screening

0.63

0.44

1.7

1.4

55.00

56.61

—

Astigmatism

1.37

0.44

1.6

1.4

54.43

58.37

—

Gestational [pregnancy-induced] hypertension

121

1.32

0.43

1.0

1.4

67.55

60.50

0.27

107

Abnormal serum enzyme levels

558

0.87

0.43

1.3

1.4

68.44

62.82

0.64

454

Carbimazole or st.post thyroidectomy, condition for graves disease

202

1.24

0.43

1.6

1.5

58.53

61.51

0.13

167

Polycythaemia vera

1.62

0.43

1.2

1.5

59.80

53.80

—

Anorexia (incl.atypical)

1.61

0.43

1.0

1.3

57.80

55.96

—

Pollen allergy

0.66

0.42

1.0

1.4

62.33

56.91

—

Respiratory tuberculosis, confirmed

1.57

0.42

1.4

80.40

64.50

—

Puerperal sepsis

1.38

0.42

1.3

1.4

65.86

64.04

—

Corneal ulcer

221

1.22

0.42

1.1

1.5

55.59

63.49

0.47

180

Inguinal or femoral hernia, bilateral

203

1.23

0.42

1.6

1.4

72.17

66.78

0.36

170

Respiratory tuberculosis, bacteriologically and histologically confirmed

1.52

0.41

1.4

80.40

65.74

—

Shoulder region

0.00

0.41

0.0

1.5

—

64.30

—

Benign neoplasm: Brain, supratentorial

0.00

0.41

0.0

1.3

—

63.44

—

ILD medications: acetylcysteine

0.00

0.41

0.0

1.3

—

67.60

—

Brain glioblastoma

0.00

0.41

0.0

1.3

—

62.50

—

Use of amantadine

0.00

0.41

0.0

1.3

—

62.73

—

Other prurigo

0.00

0.40

0.0

1.3

—

59.70

—

Other specified/unspecified necrotizing vasculopathies

0.00

0.40

0.0

1.5

—

68.50

—

False labour

0.67

0.40

1.3

1.5

29.71

61.08

—

Benign neoplasm of other and unspecified sites

1.47

0.40

1.2

64.80

52.58

—

Other and unspecified injuries of lower leg

1.33

0.40

1.3

1.2

47.75

60.39

—

Chronic gastritis

464

1.14

0.40

1.3

1.4

67.64

63.78

0.39

388

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

1.32

0.40

1.4

1.3

46.50

53.54

—

Pregnancy hypertension

217

1.20

0.39

1.5

1.3

67.09

61.56

0.38

188

Delivery, wide proxy

191

0.84

0.39

1.3

61.22

64.04

0.15

160

Benign neoplasm: Skin of upper limb, including shoulder

0.00

0.39

0.0

1.3

—

57.38

—

Suppurative and unspecified otitis media

263

1.18

0.39

1.3

1.4

61.76

61.37

0.02

219

Mood disorders

154

938

1.08

0.39

1.4

56.89

62.30

1.11

130

765

Conjunctivitis (acute, non atopic)

287

1.18

0.39

1.3

1.4

53.33

63.68

0.88

237

Calculus of kidney and ureter

494

1.13

0.38

1.6

1.4

64.80

64.08

0.05

403

Alzheimer disease, excluding more controls

245

0.84

0.37

1.1

1.5

65.59

66.81

0.06

198

Hydrocephalus

116

0.69

0.37

1.1

1.4

77.13

70.40

—

severe traumatic brain injury, does not include concussion

393

1.15

0.36

1.4

1.5

64.75

65.47

0.05

311

Diseases of middle ear and mastoid

523

1.11

0.36

1.3

1.4

65.19

61.56

0.42

438

Deep bite

0.63

0.36

2.0

1.3

46.60

55.03

—

Laparoscopic right hemicolectomy

0.65

0.35

1.2

1.5

66.08

63.15

—

Infective bursitis

1.43

0.35

1.2

1.5

54.00

57.43

—

Malignant neoplasm of oral cavity, excluding all cancers (controls excluding all cancers)

1.43

0.35

1.3

1.4

51.83

55.28

—

Iridocyclitis

301

1.16

0.34

1.1

1.4

60.72

64.24

0.21

246

Symptoms and signs involving speech and voice

469

0.87

0.34

1.7

1.4

62.83

64.91

0.14

392

Ingrowing nail

1.36

0.34

1.3

1.2

29.33

54.53

—

Nonspecific lymphadenitis

1.36

0.34

2.8

1.3

64.17

61.00

—

Enthesopathies of lower limb, excluding foot

254

0.83

0.34

1.4

1.3

56.31

65.63

0.61

208

Hypertrophic disorders of skin

1.33

0.33

1.5

1.3

44.83

57.28

—

Carcinoma in situ of cervix uteri

1.33

0.33

1.0

1.4

50.83

61.51

—

Benign leiomyoma with endometriosis

145

1.24

0.33

1.4

70.25

61.78

0.47

121

Complications predominantly related to the puerperium

136

1.25

0.33

1.3

1.4

60.50

62.61

0.07

123

Irregular menses

241

0.84

0.33

1.6

1.3

55.53

61.85

0.38

203

Normal-pressure hydrocephalus

0.67

0.33

1.2

1.4

79.17

64.87

—

Any dementia, excluding more controls

514

0.90

0.32

1.3

1.4

59.35

68.41

1.03

417

Myalgia

241

0.83

0.31

1.5

1.4

56.00

63.73

0.34

203

Depression

133

855

1.07

0.31

1.4

55.30

62.26

1.45

112

702

Fracture of shoulder and upper arm

503

1.11

0.31

1.2

1.4

57.60

65.89

0.97

415

Event of undetermined intent

1.32

0.30

1.0

1.3

61.00

56.26

—

Sciatica+with lumbago

632

1.10

0.30

1.4

1.3

53.80

62.14

1.09

521

Shoulder lesions

135

773

1.07

0.30

1.4

60.16

62.46

0.33

120

637

Nail disorders

1.33

0.30

1.2

1.3

39.30

55.02

—

Haemorrhoids and perianal venous thrombosis

473

0.89

0.30

1.4

64.41

65.46

0.07

387

Anti-inflammatory and antirheumatic products, non-steroids

281

1.11

0.30

1.4

1.5

62.88

65.97

0.27

226

Superficial injury of abdomen, lower back and pelvis

166

1.21

0.29

1.4

1.5

55.07

64.04

0.45

134

Single spontaneous delivery

212

1.13

0.29

1.6

1.3

65.76

63.48

0.17

176

Mood [affective] disorders

151

935

1.06

0.28

1.4

56.66

62.38

1.19

128

762

Meniscus derangement

609

0.92

0.28

1.4

58.37

62.46

0.43

513

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

252

1.15

0.28

1.5

1.3

68.85

59.96

0.82

217

IBD patients in KELA-register

223

1.17

0.28

1.3

1.5

38.26

63.96

2.89

184

Benign neoplasm of urinary organs

1.29

0.28

2.0

1.3

66.38

62.89

—

Other systemic involvement of connective tissue (FG)

353

1.13

0.27

1.2

1.4

65.07

67.84

0.19

302

Cystitis

125

814

0.94

0.27

1.4

64.54

63.63

0.11

674

Biological medication for rheuma

121

0.74

0.27

1.2

1.5

49.67

56.15

—

101

Other diseases of hard tissues of teeth

622

0.92

0.26

1.2

1.4

62.13

62.16

0.00

515

Foreign body in alimentary tract

1.21

0.26

1.0

1.3

31.50

58.08

—

Other disorders of bladder

213

0.84

0.25

1.4

1.5

67.58

67.01

0.02

178

Synovial cyst of popliteal space [Baker]

1.25

0.24

1.1

1.5

57.40

66.45

—

Open wound of wrist and hand

523

0.91

0.24

1.3

1.4

50.89

61.84

1.24

444

Other and/or unspecified nontoxic goitre

0.73

0.24

1.2

1.4

60.17

66.55

—

Cholesteatoma of middle ear

0.71

0.24

1.3

1.5

61.33

62.78

—

Other systemic involvement of connective tissue

379

1.11

0.23

1.2

1.4

65.07

66.02

0.06

313

Malignant melanoma of skin

180

1.17

0.23

1.6

1.5

56.67

66.07

0.54

146

Urolithiasis

543

1.09

0.23

1.6

1.4

64.85

63.09

0.15

439

Obesity, other/unspecified

342

1.11

0.22

1.3

1.4

65.76

61.07

0.38

283

Postpartum haemorrhage due to retained placenta

1.22

0.22

1.0

1.7

65.40

55.63

—

Cerebral amyloid angiopathy

0.00

0.21

0.0

1.6

—

60.20

—

Inflammatory bowel disease, strict (require KELA)

229

1.14

0.21

1.3

1.5

38.26

62.47

2.66

190

Acute and subacute iridocyclitis

248

1.13

0.21

1.1

1.5

57.80

64.58

0.43

201

Melanocytic naevi of ear and external auricular canal

0.00

0.21

0.0

1.6

—

85.60

—

Frontotemporal dementia, wide, incl. Pick's disease

0.00

0.21

0.0

1.5

—

59.33

—

Carcinoma in situ of rectum

0.00

0.21

0.0

1.5

—

55.17

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites

0.00

0.21

0.0

1.4

—

68.80

—

Human immunodeficiency virus [HIV] disease resulting in other conditions

0.00

0.21

0.0

1.2

—

40.18

—

Artrosis, including avohilmo

141

813

0.95

0.21

1.4

62.16

62.11

0.01

114

659

Hydrocephalus in other diseases

0.00

0.21

0.0

1.4

—

64.57

—

Exposure to excessive heat of man-made origin

0.00

0.21

0.0

1.3

—

69.00

—

Pregnancy with abortive outcome

345

1.08

0.21

1.4

1.3

64.49

62.19

0.23

290

Tumor necrosis factor alpha inhibitors

104

0.77

0.21

1.3

1.5

54.62

56.98

—

Crohn's disease of large intestine

1.16

0.21

1.2

1.3

55.40

61.77

—

Causalgia

0.00

0.21

0.0

1.5

—

66.00

—

Polymyalgia rheumatica

211

1.14

0.20

1.3

1.5

63.06

67.16

0.24

167

Noninflammatory disorders of female genital tract

206

0.90

0.20

1.2

1.3

55.31

62.93

0.70

173

Use of entacapone

0.00

0.20

0.0

1.4

—

68.88

—

Migraine with aura, drug-induced

0.00

0.20

0.0

1.4

—

56.11

—

Aphakia

0.00

0.20

0.0

1.5

—

72.50

—

Coxibs

280

1.08

0.20

1.5

61.62

65.96

0.40

225

Delivery

212

1.10

0.20

1.6

1.3

67.25

63.48

0.31

176

Polyarthrosis

285

1.11

0.20

1.2

1.4

62.68

67.68

0.30

237

Other enthesopathies

355

1.10

0.20

1.5

1.3

63.87

63.51

0.02

299

Unspecified dementia

216

0.88

0.19

1.4

1.5

59.59

69.93

0.51

172

Diseases of external ear

469

0.92

0.19

1.3

1.4

67.86

63.90

0.31

386

Episcleritis

1.20

0.19

1.8

1.4

41.00

57.85

—

Endometriosis diagnosis and infertility diagnosis occurring together

1.20

0.19

1.5

1.4

61.33

59.33

—

Other headache syndromes

479

0.92

0.19

1.3

1.4

57.22

64.04

0.64

400

Residual foreign body in soft tissue

1.18

0.19

2.2

1.5

53.83

61.68

—

Other symptoms and signs involving cognitive functions and awareness

733

1.06

0.19

1.4

60.65

63.77

0.33

596

Extrapyramidal and movement disorders

602

0.93

0.19

1.5

1.4

57.18

63.71

0.76

490

Undefined dementia

219

0.88

0.18

1.4

1.5

59.59

70.96

0.58

166

Disorders of breast

404

0.92

0.18

1.3

72.51

62.20

1.45

335

Early lumbar disc prolapse operation

1.15

0.17

2.0

1.5

59.57

47.71

—

Gonarthrosis [arthrosis of knee](FG)

119

733

0.96

0.17

1.4

1.3

62.04

62.79

0.08

616

Generalized anxiety disorder

1.22

0.17

1.3

1.4

45.40

58.35

—

Lichen planus

148

1.15

0.16

1.4

59.50

63.42

0.14

124

Other osteochondropathies

1.18

0.16

2.1

1.5

62.75

56.14

—

Artificial joint operation, meniscal resection

151

1044

0.96

0.16

1.4

58.80

62.44

0.58

123

856

Brachial plexus disorders

1.14

0.16

1.4

1.3

42.00

60.34

—

Fracture at wrist and hand level

389

1.08

0.15

1.5

1.4

53.16

63.78

1.00

326

Panic disorder

1.21

0.15

1.4

48.30

57.70

—

Other intervertebral disc disorders

126

803

0.96

0.15

1.5

1.4

56.72

62.51

0.98

103

654

Excessive, frequent and irregular menstruation

206

0.92

0.15

1.4

1.3

60.50

62.93

0.20

173

Other bursopathies

178

1.12

0.15

1.1

1.4

46.92

67.54

1.08

148

Adverse effects, not elsewhere classified

171

0.88

0.14

1.5

49.40

61.84

—

142

Squamous cell neoplasms and carcinomas of the skin

246

1.10

0.14

1.5

56.55

69.91

1.08

197

Injury of muscle and tendon at lower leg level

212

0.90

0.14

1.3

1.4

44.79

62.93

1.14

173

Fall on same level involving ice and snow

756

0.95

0.13

1.4

60.34

63.03

0.26

624

Lichen planus, including avohilmo

218

1.10

0.13

1.5

1.4

52.06

63.65

0.61

184

Foreign body on external eye

180

0.89

0.13

1.8

1.4

45.60

59.91

—

152

Gonarthrosis

105

626

0.96

0.12

1.4

1.3

59.96

62.75

0.33

525

Disorders of ocular muscles, binocular movement, accommodation and refraction

507

1.06

0.12

1.4

65.69

63.14

0.24

427

Pregnancy, childbirth and the puerperium

175

1.08

0.12

1.4

1.3

56.61

63.80

0.51

146

Symptoms and signs involving the nervous and musculoskeletal systems

835

1.04

0.12

1.4

69.59

62.33

1.23

678

Functional dyspepsia

307

1.08

0.12

1.4

1.3

60.46

63.33

0.19

258

Polycystic ovarian syndrome, consortium definition

385

1.05

0.12

1.5

1.3

57.91

62.90

0.62

319

Superficial injury of head

278

1.08

0.12

1.4

1.5

59.43

64.50

0.41

229

Diseases of inner ear

826

0.96

0.11

1.4

68.77

62.65

1.02

684

Other symptoms and signs involving the nervous and musculoskeletal systems

542

1.05

0.11

1.4

70.72

63.54

0.90

454

Other noninflammatory disorders of uterus, except cervix

183

1.08

0.11

1.2

1.3

63.26

64.26

0.05

153

Neuromuscular dysfunction of bladder

124

1.13

0.11

1.1

1.5

75.89

65.13

—

103

Other fall from one level to another

281

0.92

0.11

1.8

1.4

56.90

61.66

0.28

228

Vascular dementia (undefined)

1.17

0.11

1.5

1.6

82.20

67.45

—

Injuries to the knee and lower leg

178

1045

0.97

0.11

1.3

1.4

59.89

62.58

0.45

145

855

Fall on and from stairs and steps

338

1.07

0.10

1.3

1.5

50.68

64.09

1.31

279

Effects of foreign body entering through natural orifice

311

0.93

0.10

1.5

1.4

45.22

62.71

1.80

261

Carpal tunnel syndrome

758

1.04

0.10

1.4

57.52

62.52

0.62

626

Foreign body in respiratory tract

1.14

0.10

1.2

1.3

66.40

57.62

—

Vitamin B12 deficiency anaemia

176

0.91

0.09

1.3

1.5

59.55

67.92

0.65

143

Sequelae of other and unspecified infectious and parasitic diseases

1.04

0.09

1.6

1.3

47.20

53.10

—

Other abnormal findings of blood chemistry

1.11

0.09

2.0

1.4

45.00

56.50

—

Melanoma in situ

1.09

0.09

1.7

1.4

65.67

59.60

—

Other disorders of eyelid

740

0.97

0.08

1.3

1.4

64.63

64.23

0.03

601

Malignant melanoma

243

1.07

0.08

1.6

1.5

59.81

65.88

0.40

194

Scleritis and episcleritis

1.05

0.08

1.8

1.4

41.00

60.61

—

Other disorders of gingiva or/and edentulous alveolar ridge

1.03

0.08

1.3

1.5

69.17

56.75

—

Mixed and other personality disorders

1.03

0.08

1.2

1.5

53.33

58.20

—

Transport accidents

503

1.04

0.08

1.4

58.25

62.60

0.43

420

UC patients in KELA-register (code 208), prior to 1994

0.83

0.08

1.2

1.4

34.00

61.92

—

Schizoaffective disorder

0.82

0.08

1.2

1.4

86.00

54.96

—

Pilonidal cyst

0.78

0.08

1.0

1.3

55.00

53.74

—

Female infertility, cervigal, vaginal, other or unspecified origin

124

0.92

0.08

1.1

1.3

70.12

60.13

0.70

106

Other noninflammatory disorders of vulva and perineum

1.08

0.08

1.3

1.4

71.29

64.95

—

Arthrosis

120

643

1.03

0.08

1.4

64.59

62.79

0.22

538

Divergent concomitant strabismus

1.04

0.08

1.4

1.5

65.86

60.02

—

Cervical disc disorders

539

1.04

0.08

1.4

61.52

63.48

0.16

445

Varicose veins

107

788

1.03

0.07

1.3

1.4

64.62

62.89

0.18

653

Endometriosis ASRM stages 3,4

176

1.08

0.07

1.2

1.3

50.64

62.18

0.68

150

Leiomyoma of uterus

357

1.04

0.07

1.3

61.26

62.90

0.14

303

Exposure to other specified factors

877

1.03

0.07

1.3

1.4

60.74

61.69

0.09

724

Malignant neoplasm of stomach

1.06

0.07

1.8

1.4

64.22

65.51

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

0.89

0.06

1.3

1.5

70.75

58.52

—

Blepharochalasis

456

0.96

0.05

1.3

1.4

63.11

65.15

0.13

376

Chronic sinusitis

553

1.03

0.05

1.6

1.4

54.46

62.34

0.92

455

Inflammatory diseases of female pelvic organs

387

1.03

0.05

1.5

1.3

62.47

62.54

0.00

327

Other degenerative diseases of the nervous system

352

1.03

0.05

1.1

1.4

60.65

63.48

0.20

292

Excessive attrition of teeth

241

1.04

0.05

1.2

1.5

63.66

61.49

0.15

203

Ectopic pregnancy

100

1.10

0.05

1.7

1.4

82.36

61.33

1.83

Injuries to the shoulder and upper arm

130

1072

1.02

0.05

1.3

1.4

59.69

62.43

0.39

113

873

Erectile dysfunction

179

1.06

0.05

1.3

1.5

65.57

68.96

0.15

144

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

297

1.04

0.04

1.3

1.4

57.29

60.17

0.16

247

Recurrent or chronic depression

279

1.04

0.04

1.6

1.3

53.57

62.44

0.72

231

Selective serotonin reuptake inhibitors

164

852

1.01

0.04

1.4

62.28

62.94

0.08

137

697

Benign paroxysmal vertigo

417

1.03

0.04

1.5

1.4

73.65

64.96

1.31

344

Ovarian cyst

204

0.96

0.04

1.7

1.3

62.36

63.26

0.05

171

Superficial injury of wrist and hand

170

1.06

0.04

1.3

1.5

48.83

62.17

0.74

146

Redundant prepuce, phimosis and paraphimosis

279

0.96

0.03

1.5

1.4

66.05

60.04

0.41

235

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

371

0.97

0.03

1.4

60.26

63.39

0.19

308

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

692

1.02

0.03

1.5

1.4

52.72

61.80

1.15

569

Endometriosis

203

0.97

0.03

1.4

1.3

65.16

63.61

0.10

170

Vascular dementia

173

0.95

0.03

1.4

1.5

79.22

69.02

—

136

Strabismus

300

1.03

0.02

1.3

1.4

64.88

65.12

0.01

244

Other abnormal uterine and vaginal bleeding

185

0.96

0.02

1.4

1.3

65.37

64.39

0.05

155

Lichen ruber planus, wide definition including periferal and oral lichen planus

249

0.96

0.02

1.5

1.4

52.06

63.37

0.59

211

Superficial injury of lower leg

261

1.03

0.02

1.4

64.29

63.33

0.04

215

Other and unspecified disorders of vitreous body

569

1.01

0.01

1.2

1.4

58.30

64.55

0.73

478

Radiculopathy

257

0.97

0.01

1.4

62.30

68.47

0.33

208

Medical abortion

338

1.01

0.01

1.3

63.68

62.19

0.13

284

Urticaria and erythema

393

1.02

0.01

1.5

1.4

50.36

63.18

1.27

331

Diseases of appendix

895

1.01

0.01

1.5

1.4

61.01

60.91

0.01

737

Rotator cuff syndrome

100

737

1.01

0.01

1.4

58.40

62.73

0.58

608

Use of pramipexole

326

0.98

0.00

1.4

1.5

57.36

63.96

0.44

268

Lumbar disc prolapse

732

1.00

0.00

1.5

1.4

60.20

62.25

0.22

598

Striking against or struck by other objects

360

1.00

0.00

1.3

1.4

54.42

62.67

0.71

296

Complications of internal orthopaedic prosthetic devices, implants and grafts

343

0.99

0.00

1.4

58.08

66.78

0.57

286

Follicular cysts of skin and subcutaneous tissue

234

0.98

0.00

1.5

1.4

64.50

63.26

0.05

190

Pedal cyclist injured in transport accident

234

0.98

0.00

1.4

1.5

59.76

62.24

0.11

193

Disorders of vestibular function (Vertigo)

709

0.99

0.00

1.4

69.58

63.40

0.99

592

Visual field defects

118

1.02

0.00

1.4

1.5

61.44

66.37

—

Spondylopathies (FG)

138

1.01

0.00

1.4

1.5

47.67

64.61

—

122

Lesion of ulnar nerve

182

0.99

0.00

1.7

1.4

61.06

65.38

0.18

148

Other disorders of conjunctiva

212

0.99

0.00

1.5

59.33

66.43

0.41

173

Polyp of the female genital tract

198

1.00

0.00

1.5

1.3

58.04

63.40

0.37

166

Propionic acid derivatives

281

1.00

0.00

1.5

61.15

65.97

0.47

226

Primary coxarthrosis, bilateral

525

1.01

0.00

1.4

64.35

64.31

0.00

433

Acute appendicitis

835

0.99

0.00

1.6

1.4

61.87

60.59

0.14

690

Appendicitis, broad definition

886

1.00

0.00

1.5

1.4

61.77

60.92

0.09

730

Sequelae of injuries, of poisoning and of other consequences of external causes

279

1.00

0.00

1.4

52.80

60.72

0.47

233

Ménière disease

127

1.02

0.00

1.2

1.6

68.23

65.90

0.10

101

Exposure to other and unspecified inanimate mechanical forces

0.95

0.00

1.0

1.3

77.33

53.98

—

Other acute disseminated demyelination

0.00

0.0

1.0

—

72.00

—

Carcinoma in situ of breast, intraductal

0.95

0.00

1.2

1.4

57.33

63.75

—

Family history of malignant neoplasm

0.91

0.00

1.2

1.5

66.67

64.49

—

Crushed, pushed or stepped on by crowd or human stampede

0.93

0.00

1.4

1.3

50.60

54.79

—

Bicipital tendinitis

0.94

0.00

1.2

1.5

57.40

63.07

—

Allergic colitis

0.00

0.0

1.0

—

67.40

—

Malignant neoplasm of oral cavity

1.02

0.00

1.4

1.3

53.20

57.95

—

Mental disorders, not otherwise specified

0.96

0.00

1.2

1.4

50.00

59.62

—

Premenstrual syndrome

0.00

0.0

1.2

—

74.50

—

Uterine polyps

0.98

0.00

1.6

1.4

68.25

66.42

—

Dermatitis due to substances taken internally

0.88

0.00

1.2

35.20

58.95

—

Lichenoid drug reaction

0.00

0.0

1.2

—

68.00

—

Venous complications and haemorrhoids in pregnancy

0.00

0.0

1.2

—

43.33

—

Other/unspecified reactive arthropathies

0.91

0.00

1.3

38.17

62.29

—

Routine general health check-up of defined subpopulation

0.00

0.0

1.0

—

70.67

—

Carcinoma in situ of skin of trunk

1.02

0.00

1.2

1.4

67.40

65.22

—

Other assisted single delivery

0.00

0.0

1.1

—

52.29

—

Retained placenta and membranes, without haemorrhage

1.00

0.00

1.1

1.4

52.71

64.52

—

Dermatitis due to ingested food

0.00

0.0

1.0

—

65.60

—

Unspecified human immunodeficiency virus [HIV] disease

0.00

0.0

1.4

—

40.60

—

Eating disorders

0.98

0.00

1.0

1.3

57.80

59.74

—

Dermatographic urticaria

0.96

0.00

1.2

1.4

32.60

59.44

—

Adenocarcinoma and papillary adenocarcinoma of stomach

1.02

0.00

1.8

1.3

59.20

67.78

—

Other disorders of binocular vision

0.00

0.0

1.0

—

63.40

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Lymphocytes/100 leukocytes in Pleural fluid

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS