normal pressure hydrocephalus: A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see gait disorders, neurologic), progressive intellectual decline, and urinary incontinence. Spinal fluid pressure tends to be in the high normal range. This condition may result from processes which interfere with the absorption of csf including subarachnoid hemorrhage, chronic meningitis, and other conditions. (From Adams et al., Principles of Neurology, 6th ed, pp631-3)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2126 |
4. Check minimum number of eventsNone |
2126 |
5. Include endpointsNone |
2126 |
6. Filter based on genotype QC (FinnGen only) |
1848 |
Control definitions (FinnGen only)
- Control exclude
- G6_HYDROCEPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G91
- Name in latin
- Hydrocephalia normotensiva
Similar endpoints
↥List of similar endpoints to
Normal-pressure hydrocephalus
based on the number of shared cases.
Similar with more cases:
- Hydrocephalus
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8138 | 4029 | 4003 |
| Only index persons | 6703 | 3428 | 3275 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.11 |
| Only index persons | 0.13 | 0.13 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 74.05 | 74.92 | 73.17 |
| Only index persons | 73.83 | 74.66 | 72.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1848 | 869 | 979 |
| Unadjusted period prevalence (%) | 0.38 | 0.31 | 0.45 |
| Median age at first event (years) | 73.57 | 73.84 | 73.32 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1897
- Matched controls
- 18970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
307.7
1897
*
AA1AA
NOMESCO Finland
Head X-ray examination
70.0
307.7
296
50
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
21.9
307.7
677
468
AA1AD
NOMESCO Finland
CT of head and brain
6.4
307.7
1345
5234
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
5715.7
307.7
1104
5
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
3777.2
307.7
327
*
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
17.8
307.7
342
232
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
287.0
268
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
2861.9
275.8
260
*
AAF00
NOMESCO Finland
Ventriculostomy
80.1
264.2
141
19
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
237.6
223
*
AAF15
NOMESCO Finland
Ventriculoatrial shunt
2275.1
225.5
214
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.5
174.3
388
841
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
871.4
165.3
160
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
153.2
377
886
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
141.5
134
*
P20
ICPC
Memory disturbance
3.4
137.8
751
3076
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
128.6
122
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
446.7
127.5
126
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
1233.7
120.2
116
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
5.8
118.2
236
457
L28
ICPC
Limited function/disability (L)
2.8
95.6
750
3622
SPAT1053
SPAT
Memory test
2.8
91.8
654
2995
R42
ICD-10 Finland
Dizziness and giddiness
2.7
89.9
758
3772
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
4.6
87.6
224
533
F03
ICD-10 Finland
Unspecified dementia
4.0
86.8
282
803
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.2
82.6
246
657
SPAT1216
SPAT
Assessment of functional ability
2.7
81.7
613
2854
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
12.2
80.3
81
69
N99
ICPC
Neurological disease other
9.1
79.4
99
114
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.1
79.1
395
1476
SPAT1229
SPAT
Assessment of need for aid
3.3
78.0
343
1187
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.0
77.4
431
1711
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.8
76.5
263
776
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
200.5
74.7
77
*
R53
ICD-10 Finland
Malaise and fatigue
2.4
70.5
710
3753
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
69.5
728
3910
N05AX08
ATC
risperidone; systemic
3.1
68.7
346
1291
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.0
66.8
352
1346
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.1
64.9
318
1166
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
60.4
416
1823
N03AG01
ATC
valproic acid; systemic, rectal
3.9
57.6
180
494
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
3.4
57.4
230
745
A28
ICPC
Limited function/disability NOS
2.2
57.0
687
3848
TAB00
NOMESCO Finland
Lumbar puncture
4.6
56.4
140
323
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
55.8
531
2690
N06DA02
ATC
donepezil; oral
2.8
55.1
325
1312
N28
ICPC
Limited function/disability (N)
5.8
54.7
102
183
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
54.4
52
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
54.1
880
5511
U04
ICPC
Incontinence urine
3.0
53.2
266
981
N05AH04
ATC
quetiapine; oral
2.5
52.1
389
1760
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.3
51.7
510
2611
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.3
51.3
217
725
SPAT1234
SPAT
Support of social functional capacity
3.1
51.2
235
824
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
7.7
50.3
71
95
G30.1
ICD-10 Finland
Alzheimer disease with late onset
2.6
50.2
332
1415
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.6
49.4
323
1369
G04BD08
ATC
solifenacin; oral
2.9
49.2
252
940
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
5.8
48.4
90
161
N29
ICPC
Neurological sympt/complt other
5.8
47.3
89
161
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
47.1
45
*
G04BD12
ATC
mirabegron; oral
2.4
46.1
401
1934
N06DX01
ATC
memantine; oral
2.4
46.1
377
1770
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
5.7
44.8
85
155
G20
ICD-10 Finland
Parkinson disease
3.7
44.4
150
433
S06.0
ICD-10 Finland
Concussion
2.6
44.0
302
1306
N06AB10
ATC
escitalopram; oral
2.4
43.7
353
1645
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.6
43.1
150
442
N06DA03
ATC
rivastigmine; oral, transdermal
2.8
42.7
231
885
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
40.3
698
4350
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.9
40.3
208
776
G04BD07
ATC
tolterodine; oral
3.0
39.9
194
700
F06.7
ICD-10 Finland
Mild cognitive disorder
3.4
39.6
150
466
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.2
38.1
161
535
N05AH03
ATC
olanzapine; systemic
3.5
38.1
140
427
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
37.7
427
2276
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
8.1
37.2
50
63
N06AB04
ATC
citalopram; systemic
2.1
36.8
455
2505
SPAT1254
SPAT
Administration of medicine
2.1
36.4
442
2416
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
2.8
35.2
185
695
A04
ICPC
Weakness/tiredness general
2.1
34.8
428
2345
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
2.8
34.5
180
674
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
34.5
33
*
P70
ICPC
Dementia
3.3
34.4
138
444
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
34.2
453
2549
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
33.4
32
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
6.8
33.2
52
78
M48.0
ICD-10 Finland
Spinal stenosis
2.1
32.9
384
2059
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.0
31.6
147
516
R41.0
ICD-10 Finland
Disorientation, unspecified
3.1
30.9
136
462
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
12.1
30.8
31
26
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
4.5
30.4
76
176
WYA20
NOMESCO Finland
Home visit
3.7
30.2
100
284
N18
ICPC
Paralysis/weakness
4.0
30.2
87
224
SPAT1101
SPAT
Orthostatic test
2.7
29.7
175
697
R32
ICD-10 Finland
Unspecified urinary incontinence
3.4
29.6
110
337
XA800
NOMESCO Finland
Neuropsychological investigation
3.8
29.4
91
247
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
6.7
29.0
46
70
W19
ICD-10 Finland
Unspecified fall
2.2
28.7
272
1341
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
7.1
28.5
43
62
N05AX12
ATC
aripiprazole; systemic
5.5
28.4
55
102
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.8
28.0
87
237
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
27.7
205
909
R51.80
ICD-10 Finland
Headache
2.1
27.6
280
1416
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
27.1
26
*
SPAT1301
SPAT
No procedures
1.7
26.6
718
4971
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
26.5
242
1174
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
26.4
337
1855
R1250
NOMESCO Finland
Evaluation of functional capability
3.7
26.3
84
233
SPAT1252
SPAT
Overall medication plan or its review
2.3
25.6
217
1020
R26.0
ICD-10 Finland
Ataxic gait
10.5
25.4
28
27
N02BE01
ATC
paracetamol; systemic, rectal
2.3
25.3
1715
15267
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.9
25.3
127
465
K90
ICPC
Stroke/cerebrovascular accident
2.9
24.1
116
415
N30.0
ICD-10 Finland
Acute cystitis
1.8
23.9
397
2375
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
3.0
23.8
110
384
N06AX11
ATC
mirtazapine; oral
1.7
23.6
670
4667
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
7.9
23.4
32
41
R55
ICD-10 Finland
Syncope and collapse
1.9
23.1
317
1782
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
8.2
22.7
30
37
N06AX16
ATC
venlafaxine; oral
2.2
22.4
217
1074
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
2.7
22.3
123
473
Z03
ICPC
Housing/neighbourhood problem
6.5
22.2
36
56
SPAT1042
SPAT
Guidance concerning balance maintenance
7.4
22.1
32
44
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.0
22.0
64
166
R5110, ,
SPAT
2.0
22.0
251
1321
N05AB03
ATC
perphenazine; systemic, rectal
3.4
22.0
79
237
N06AX26
ATC
vortioxetine; oral
2.7
21.7
122
474
N06AB06
ATC
sertraline; oral
2.2
21.6
184
865
N04AA02
ATC
biperiden; systemic
4.8
21.5
49
105
G30.8
ICD-10 Finland
Other Alzheimer disease
2.7
21.4
120
465
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.9
20.2
94
330
R27.0
ICD-10 Finland
Ataxia, unspecified
8.0
20.0
27
34
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.1
19.8
86
290
G04BD04
ATC
oxybutynin; oral, transdermal
2.2
19.8
169
795
N05BA04
ATC
oxazepam; oral
1.6
19.7
536
3658
N03AX14
ATC
levetiracetam; systemic
3.2
19.7
78
249
A29
ICPC
General symptom/complaint other
1.8
19.1
335
2025
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
2.0
19.0
232
1249
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.8
18.9
324
1945
SPAT1251
SPAT
Organisation of medication
2.5
18.7
116
473
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
18.6
362
2254
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
18.6
114
462
G04CA02
ATC
tamsulosin; oral
1.6
18.6
632
4542
N87
ICPC
Parkinsonism
3.5
18.5
63
183
A06AD11
ATC
lactulose; oral
1.7
18.4
421
2739
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.3
18.4
69
213
G04BD09
ATC
trospium; oral
2.9
18.4
86
303
SPAT1304
SPAT
Counselling and guidance related to ageing
1.9
18.0
250
1405
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
17.9
708
5255
J01CA08
ATC
pivmecillinam; oral
1.6
17.9
717
5338
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
17.8
310
1867
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.9
17.5
228
1253
Z75.5
ICD-10 Finland
Holiday relief care
4.3
17.4
44
103
R26
ICD-10 Finland
Abnormalities of gait and mobility
14.0
17.3
29
21
WX320
NOMESCO Finland
Spinalanesthesy
0.5
17.2
223
3791
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
4.0
17.2
48
121
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.8
17.1
31
54
N03AX09
ATC
lamotrigine; oral
3.2
16.9
66
209
Z02.4
ICD-10 Finland
Examination for driving licence
0.6
16.9
348
5209
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.8
16.8
261
1518
L99
ICPC
Musculoskeletal disease other
3.3
16.6
63
196
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
171.5
16.5
17
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
16.5
413
2744
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
16.4
665
4942
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.4
16.4
58
173
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
6.8
16.2
25
37
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.5
16.0
54
156
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
3.4
15.9
57
171
N05AH02
ATC
clozapine; systemic
6.7
15.8
25
38
SPAT1167
SPAT
Insertion of urinary catheter
2.4
15.6
112
489
F22.0
ICD-10 Finland
Delusional disorder
4.3
15.5
40
95
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.9
15.5
71
247
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
5.0
15.5
33
67
Z2445
NOMESCO Finland
Psychologist
3.4
15.4
54
160
SPAT1307
SPAT
Psychosocial counselling and guidance
3.0
15.3
66
222
ZXD05
NOMESCO Finland
Urgent procedure
1.5
15.2
564
4097
F05.9
ICD-10 Finland
Delirium, unspecified
2.7
15.0
81
308
N05AN01
ATC
lithium; oral
4.1
14.9
40
98
J01EA01
ATC
trimethoprim; systemic
1.5
14.4
532
3852
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
14.4
158
817
L29
ICPC
Musculoskeletal sympt/complt other
1.9
14.4
191
1055
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.1
14.4
135
659
G04BD10
ATC
darifenacin; oral
4.9
14.3
31
64
AXX01, ,
SPAT
2.2
14.2
129
621
N03AB02
ATC
phenytoin; systemic
4.0
14.2
40
102
S01.0
ICD-10 Finland
Open wound of scalp
1.9
14.1
197
1107
SPAT1246
SPAT
Screening of depression or other psychiatric problem
3.2
13.9
56
181
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
13.8
610
4578
Z08
ICPC
Social welfare problem
4.6
13.8
32
70
Z00.0
ICD-10 Finland
General medical examination
1.6
13.7
381
2583
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.2
13.7
120
570
N17
ICPC
Vertigo/dizziness
1.7
13.5
307
1981
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.2
13.5
53
169
2132
FHL
Ventricular operators sunt
141.0
13.5
14
*
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
6.1
13.4
23
38
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
3.3
13.3
49
150
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.8
13.3
232
1393
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
10.5
13.2
25
24
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
13.2
164
886
G04BD11
ATC
fesoterodine; oral
2.5
13.1
83
342
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.2
13.1
52
167
T90.5
ICD-10 Finland
Sequelae of intracranial injury
4.7
13.1
30
65
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.9
13.1
183
1028
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
13.0
159
853
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.3
12.9
96
426
SPAT1262
SPAT
Handing over of treatment supplies
1.6
12.8
382
2630
N05AF03
ATC
chlorprothixene; systemic
3.5
12.7
43
125
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
+∞
12.5
12
*
G91
ICD-10 Finland
Hydrocephalus
+∞
12.5
12
*
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.3
12.5
94
419
J01MA02
ATC
ciprofloxacin; systemic
1.4
12.3
784
6271
N06AB03
ATC
fluoxetine; oral
1.8
12.3
202
1191
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
37.8
12.2
15
*
Z11
ICPC
Compliance/being ill problem
4.4
12.2
30
69
G30.0
ICD-10 Finland
Alzheimer disease with early onset
3.8
12.0
36
96
SPAT1244
SPAT
Occupational therapy
4.0
12.0
34
87
188
Kela drug reimbursment
Psychosis requiring demanding treatment
8.7
12.0
25
29
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.2
12.0
31
74
P03
ICPC
Feeling depressed
2.2
12.0
104
492
130
Kela drug reimbursment
Malignant tumour
0.4
11.9
53
1348
359
Kela drug reimbursment
Mirabegroni
4.7
11.9
27
58
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
3.2
11.8
46
146
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
11.7
257
3853
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
11.6
582
4445
AAA10
NOMESCO Finland
Biopsy through craniotomy
65.4
11.6
13
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
3.4
11.5
40
118
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
11.5
216
1322
N05AA02
ATC
levomepromazine; systemic
2.5
11.5
73
302
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
11.5
11
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.7
11.4
26
56
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
4.1
11.4
31
77
N05AC02
ATC
thioridazine; oral
3.3
11.4
42
129
N06DA04
ATC
galantamine; oral
2.2
11.3
90
411
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
0.6
11.3
289
4192
G72.8
ICD-10 Finland
Other specified myopathies
2.8
11.3
55
199
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
8.1
11.1
24
30
P76
ICPC
Depressive disorder
2.4
11.1
72
301
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
11.1
688
5453
N05BA01
ATC
diazepam; systemic, rectal
1.6
11.0
249
1601
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
4.8
11.0
24
50
-2, ,
ICPC
4.8
11.0
24
50
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
2.7
10.9
58
220
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
4.1
10.9
29
71
J01DB01
ATC
cefalexin; oral
1.5
10.9
1426
12816
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
8.3
10.8
23
28
K91
ICPC
Cerebrovascular disease
2.9
10.7
48
166
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.6
10.7
313
2140
183
Kela drug reimbursment
Lamotrigin and topiramate
5.3
10.6
21
40
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
10.5
76
334
2133
FHL
Suntin revisio
110.6
10.4
11
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
5.5
10.4
20
37
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
10.4
142
791
N39.8
ICD-10 Finland
Other specified disorders of urinary system
4.2
10.4
27
65
N80
ICPC
Head injury other
2.7
10.3
56
215
AA1ED
NOMESCO Finland
Trauma CT of head and neck
4.4
10.3
25
57
SPAT1139
SPAT
Nutrition survey
2.2
10.3
86
402
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
9.2
10.0
20
22
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
2.7
10.0
52
195
P99
ICPC
Psychological disorders other
3.3
9.9
37
115
R41.3
ICD-10 Finland
Other amnesia
2.1
9.7
91
445
SPAT1157
SPAT
Guidance concerning treatment of mouth and mucous membranes
3.3
9.6
36
112
F20.9
ICD-10 Finland
Schizophrenia, unspecified
3.6
9.5
31
88
R11
ICD-10 Finland
Nausea and vomiting
1.7
9.4
178
1091
A27
ICPC
Fear of other disease NOS
1.9
9.4
114
611
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.0
9.4
94
471
C91.2
ICD-10 Finland
Subacute lymphocytic leukemia
+∞
9.4
9
*
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
8.1
9.3
20
25
ZXA00
NOMESCO Finland
Right side
1.4
9.3
544
4238
G04CB01
ATC
finasteride; oral
1.5
9.3
296
2055
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
0.6
9.3
211
3161
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.7
9.3
29
80
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
2.6
9.3
52
203
R23.8
ICD-10 Finland
Other and unspecified skin changes
0.6
9.2
191
2924
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
4.4
9.1
22
50
S06.3
ICD-10 Finland
Focal brain injury
3.4
9.0
32
96
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
18.7
8.9
13
7
-, ,
ICD-10 Finland
2.5
8.8
54
220
Y96.9
ICD-10 Finland
Unspecified type of accident
3.0
8.8
39
134
R33
ICD-10 Finland
Retention of urine
1.6
8.7
216
1420
S70.0
ICD-10 Finland
Contusion of hip
1.9
8.6
101
535
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.7
8.6
173
1079
F31
ICD-10 Finland
Bipolar affective disorder
7.0
8.5
20
29
I95.1
ICD-10 Finland
Orthostatic hypotension
1.8
8.5
120
677
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.4
311
2225
2124
FHL
Intracranial pressure measurement, intraventricular
90.5
8.4
9
*
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.1
8.4
80
394
N88
ICPC
Epilepsy
4.9
8.4
18
37
S72.0
ICD-10 Finland
Fracture of neck of femur
1.8
8.4
133
777
SPAT1279
SPAT
Preparation of immediate hospitalisation
2.8
8.3
40
144
N06AX03
ATC
mianserin; oral
2.0
8.3
92
478
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
9.5
8.3
16
17
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
9.5
8.3
16
17
L89
ICD-10 Finland
Decubitus ulcer and pressure area
2.3
8.2
60
265
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
3.5
8.2
28
82
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
8.2
438
3351
G41.2
ICD-10 Finland
Complex partial status epilepticus
14.5
8.2
13
9
R50.9
ICD-10 Finland
Fever, unspecified
1.5
8.2
277
1946
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
2.9
8.1
36
124
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
4.8
8.1
18
38
P29
ICPC
Psychological sympt/compl other
2.1
8.1
73
352
H02AB02
ATC
dexamethasone; systemic
0.5
8.1
71
1386
G21.8
ICD-10 Finland
Other secondary parkinsonism
11.7
8.1
14
12
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.3
8.0
57
249
Z29
ICPC
Social problem NOS
2.5
8.0
48
194
E0000UV, ,
ATC
1.3
8.0
693
5718
N06AX21
ATC
duloxetine; oral
1.6
7.9
179
1148
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
7.9
329
2406
S82
ICPC
Naevus/mole
0.5
7.9
88
1593
N05CD07
ATC
temazepam; oral
1.5
7.9
272
1918
SPAT1240
SPAT
Therapeutic discussion
1.8
7.9
107
596
P01
ICPC
Feeling anxious/nervous/tense
1.9
7.8
90
476
N06AA06
ATC
trimipramine; systemic
2.5
7.8
47
191
SPAT1050
SPAT
Extensive neurological examination
2.4
7.7
51
216
F0019, G301,
ICD-10 Finland
3.1
7.7
31
101
AXX01
NOMESCO Finland
Memory assessment
3.5
7.7
26
76
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.4
7.7
52
223
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.7
7.6
23
62
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
7.6
280
1999
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.5
7.6
45
181
L57.0
ICD-10 Finland
Actinic keratosis
0.6
7.6
127
2054
U05
ICPC
Urination problems other
1.7
7.6
127
754
H81.4
ICD-10 Finland
Vertigo of central origin
3.5
7.5
25
72
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.3
7.5
53
231
SPAT1138
SPAT
Guidance concerning bowel function
2.6
7.5
43
170
SPAT1263
SPAT
Sampling
1.3
7.5
732
6126
SPAT1172
SPAT
Guidance concerning hydration
2.1
7.5
69
336
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.8
7.4
116
674
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.1
7.4
30
98
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
7.4
76
385
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
2.4
7.4
50
214
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
2.8
7.4
36
131
P72
ICPC
Schizophrenia
3.3
7.4
27
83
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
7.7
7.4
16
21
N03AF02
ATC
oxcarbazepine; oral
2.3
7.3
55
247
2139
FHL
Other measure in this category
+∞
7.3
7
*
2130
FHL
Ventricular atrial shunt
+∞
7.3
7
*
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
2.0
7.3
73
367
SPAT1276
SPAT
Outlining of treatment with patient or their family members
2.2
7.2
59
274
N06AB05
ATC
paroxetine; oral
2.0
7.1
73
370
F00.9
ICD-10 Finland
Dementia in Alzheimer disease, unspecified
3.4
7.1
25
75
M54.5
ICD-10 Finland
Low back pain
1.3
7.1
556
4505
N06AG02
ATC
moclobemide; oral
2.0
7.0
71
358
XKD00
NOMESCO Finland
Uroflowmetry
1.4
7.0
364
2763
SPAT1014
SPAT
Treatment of eyes
2.3
7.0
51
226
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.5
7.0
193
1299
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.6
7.0
39
153
Z60.8
ICD-10 Finland
Other problems related to social environment
6.3
6.9
17
27
N03AX18
ATC
lacosamide; systemic
5.5
6.9
19
35
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
2.3
6.9
51
228
A10BH01
ATC
sitagliptin; oral
1.5
6.8
208
1429
S22.3
ICD-10 Finland
Fracture of rib
1.6
6.8
144
909
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.7
6.8
258
3508
207
Kela drug reimbursment
Chronic arrhythmias
0.7
6.7
242
3322
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.6
6.7
162
2408
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
0.5
6.7
75
1357
N03AF01
ATC
carbamazepine; oral, rectal
1.8
6.7
101
583
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
3.7
6.6
20
54
XKC03
NOMESCO Finland
Water cystometry
2.0
6.6
64
318
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
0.2
6.5
11
466
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
10.1
6.5
12
12
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.0
6.5
64
320
N02AA05
ATC
oxycodone; systemic
1.3
6.5
440
3481
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
2.9
6.5
29
101
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.6
6.5
107
1737
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.1
6.5
26
85
SPAT1235
SPAT
Mental health, emotional support
6.2
6.5
16
26
D33.30
ICD-10 Finland
Acoustic neuroma
5.3
6.5
18
34
F25
ICD-10 Finland
Schizoaffective disorders
70.1
6.4
7
*
M01AC06
ATC
meloxicam; systemic, rectal
1.3
6.4
595
4922
F01.9
ICD-10 Finland
Vascular dementia, unspecified
2.2
6.4
51
235
A10BA02
ATC
metformin; oral
1.3
6.4
591
4885
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.4
182
1233
L76
ICPC
Fracture: other
1.9
6.4
72
379
A04AA02
ATC
granisetron; systemic, transdermal
0.4
6.4
27
698
N05BA06
ATC
lorazepam; systemic, sublingual
1.7
6.3
108
645
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.0
6.3
63
317
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
5.2
6.3
18
35
N05AD01
ATC
haloperidol; systemic
2.0
6.3
67
345
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.7
6.3
101
593
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
11.1
6.3
11
10
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
9.3
6.3
12
13
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.2
6.3
48
218
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
6.3
6
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
0.7
6.3
228
3125
A10AB05
ATC
insulin aspart; parenteral
1.6
6.2
152
994
N01
ICPC
Headache
1.6
6.1
124
775
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.1
663
5589
F05.1
ICD-10 Finland
Delirium superimposed on dementia
2.9
6.1
28
99
N39.9
ICD-10 Finland
Disorder of urinary system, unspecified
2.3
6.1
42
182
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
3.8
6.1
18
48
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
3.8
6.1
18
48
IHZ04, ,
SPAT
4.1
6.1
16
39
E000001, ,
ATC
1.4
6.1
297
2231
G90.2
ICD-10 Finland
Horner syndrome
8.6
6.1
12
14
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
6.7
6.0
14
21
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
403
124
41.00
307.65
1.5
1.3
—
—
—
0
0
702
261
42.11
307.65
1.9
1.2
6.25
71.52
e6/l
1.26
569
191
360
108
40.91
307.65
1.1
1.0
247.41
346.87
ng/l
2.04
122
75
361
108
41.05
307.65
1.1
1.0
30.27
47.43
ng/l
2.99
116
73
704
266
41.49
307.65
1.9
1.3
1360.40
850.96
e6/l
0.22
598
208
721
322
35.51
307.65
1.8
1.2
377.76
674.62
mg/l
8.31
715
299
509
297
23.06
307.65
1.9
1.1
3.94
3.89
mmol/l
0.32
500
272
361
108
41.05
307.65
1.1
1.0
566.47
648.95
ng/l
1.08
121
73
182
69
29.07
268.44
1.4
1.3
—
—
—
0
0
114
53
22.82
154.84
1.6
1.1
44.40
65.71
%
—
5
7
96
35
28.84
142.54
1.6
1.1
14.08
16.40
%
—
12
5
119
109
11.58
112.84
1.5
1.1
2.08
2.24
mmol/l
0.39
113
100
66
22
31.05
100.56
1.2
1.1
29.57
68.00
%
—
30
6
539
2232
2.98
91.21
9.0
8.6
—
—
—
0
0
688
3930
2.18
53.65
6.7
4.9
1.02
1.02
kg/l
3.84
441
2666
104
219
4.97
46.67
5.0
4.0
380.42
336.56
umol/l
2.04
93
193
815
5171
2.01
46.23
6.2
4.7
0.00
0.00
estimate
0.78
189
1742
179
604
3.17
41.39
3.2
3.8
3.82
3.93
mmol/l
2.42
179
596
884
5991
1.89
39.31
2.7
2.3
265.92
239.84
u/l
0.26
827
5638
660
4111
1.93
37.61
1.8
1.8
1400.91
1169.63
nmol/l
8.83
539
3040
677
4458
1.81
31.01
3.4
4.3
87.24
82.35
%
6.32
647
4368
888
6481
1.70
27.24
6.3
4.8
1.60
0.37
estimate
0.36
160
1608
1138
8915
1.69
26.35
6.0
4.6
6.15
2.37
estimate
0.26
220
2038
632
4253
1.73
25.79
2.7
3.1
2.46
2.47
mmol/l
1.60
572
3808
1120
8781
1.67
25.44
6.0
4.6
0.01
0.00
estimate
1.08
206
1960
1137
8967
1.67
25.07
6.0
4.6
0.00
0.17
estimate
0.56
192
1909
270
1411
2.07
24.26
3.9
8.5
93.73
93.79
%
0.05
270
1401
263
1374
2.06
23.62
3.9
8.5
0.71
0.64
%
2.22
263
1364
1388
11646
1.71
23.15
7.5
5.7
1807.86
1678.25
e6/l
0.05
22
197
262
1382
2.04
22.88
5.5
6.0
24.52
24.46
mmol/l
0.09
256
1317
338
1959
1.88
22.38
2.6
2.5
4.60
6.44
ug/l
2.16
288
1675
619
4474
1.57
17.55
2.2
2.6
—
—
—
0
0
1269
10722
1.55
17.44
5.1
5.2
7.00
6.91
mmol/l
0.85
1236
10276
591
4239
1.57
17.27
1.8
1.8
464.46
15175077.96
pmol/l
1.94
508
3407
951
7590
1.51
16.81
4.7
4.7
49.01
83.00
ng/l
1.18
803
6184
336
2106
1.72
16.73
4.2
7.3
124.53
119.51
g/l
4.92
329
2054
359
2294
1.70
16.65
4.0
6.8
95.73
95.25
%
0.75
352
2203
412
2737
1.65
16.44
1.9
1.9
—
—
—
0
0
208
1138
1.93
16.15
1.6
1.5
—
—
—
0
0
846
6661
1.49
15.55
2.6
3.5
2.36
2.35
mmol/l
0.82
763
5941
26
44
5.98
14.80
1.2
1.1
—
—
—
0
0
386
2592
1.61
14.56
4.1
6.6
5.02
5.08
kpa
0.66
378
2474
385
2593
1.61
14.32
4.1
6.6
12.41
11.68
kpa
1.69
376
2478
425
2964
1.56
13.53
1.9
1.9
—
—
—
0
0
377
2572
1.58
13.17
4.1
6.6
1.07
1.00
mmol/l
0.13
303
2106
33
79
4.23
12.72
1.1
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
32
76
4.27
12.46
1.1
1.2
—
—
—
0
0
1036
8699
1.42
12.43
4.1
5.0
34.85
34.41
g/l
1.93
966
8077
445
5944
0.67
11.81
1.7
1.9
1.34
1.27
mmol/l
1.25
379
4813
956
7972
1.40
11.60
2.7
3.0
—
—
estimate
—
0
0
1112
9547
1.40
11.18
13.9
20.8
1.25
1.39
inr
13.18
951
8113
517
3906
1.44
10.80
2.0
2.0
—
—
—
0
0
221
1398
1.66
10.38
2.0
3.2
59.51
57.70
ml/min/173m2
0.32
81
646
191
1197
1.66
9.29
2.1
2.5
0.67
0.61
%
1.49
191
1191
1304
14229
0.73
8.54
21.5
21.3
72.42
69.84
ml/min/173m2
5.44
1259
13398
1042
11722
0.75
8.24
26.5
26.2
14.02
14.02
%
0.03
1031
11542
1023
8911
1.32
8.07
5.3
6.6
1.20
1.21
mmol/l
3.82
947
8149
563
4516
1.35
7.81
3.0
2.9
5.11
4.89
e6/l
0.18
527
4143
19
44
4.35
7.68
1.1
1.1
—
—
—
0
0
19
44
4.35
7.68
1.1
1.1
—
—
—
0
0
32
107
3.02
7.63
1.1
1.1
—
—
—
0
0
19
45
4.25
7.48
1.1
1.1
—
—
—
0
0
99
556
1.82
7.13
2.1
1.6
—
—
—
0
0
19
48
3.99
6.89
1.1
1.1
—
—
—
0
0
150
2279
0.63
6.89
3.6
4.1
4.62
23.20
ug/l
3.36
124
1912
1256
11444
1.29
6.20
30.3
28.3
330.83
330.41
g/l
0.87
1228
11344
265
1965
1.41
5.83
2.6
2.9
4.28
4.38
kpa
0.42
255
1905
151
2208
0.66
5.77
5.6
5.4
32.95
33.92
%
0.50
94
1367
122
773
1.62
5.74
1.4
1.3
—
—
—
0
0
393
3112
1.33
5.71
1.7
2.0
28.58
29.87
s
5.07
388
3018
740
6373
1.26
5.62
4.0
3.8
86.64
91.91
e6/l
0.06
603
4990
26
93
2.82
5.57
1.3
2.1
—
—
—
0
0
412
5068
0.76
5.56
2.7
3.1
29.62
36.49
u/l
3.28
386
4751
14
24
5.87
5.53
1.1
1.3
—
—
—
0
0
987
8802
1.25
5.50
2.4
2.4
92.59
93.86
pmol/l
0.42
558
4607
720
6211
1.26
5.31
1.9
1.8
18.79
19.91
nmol/l
1.00
635
5174
13
22
5.94
5.22
1.1
1.2
—
—
—
0
0
1263
13554
0.80
5.03
4.2
4.6
1.35
1.25
mmol/l
5.78
1121
11943
137
1967
0.67
4.77
2.5
3.2
164.47
258.43
ng/l
3.03
119
1810
20
68
2.96
4.72
1.1
1.0
—
—
—
0
0
143
2026
0.68
4.64
2.4
2.6
10.53
9.79
umol/l
0.10
115
1801
791
6981
1.23
4.54
2.4
2.3
—
—
—
0
0
20
70
2.88
4.50
1.2
1.2
—
—
—
0
0
786
6939
1.23
4.48
4.8
4.4
213.00
123.93
e6/l
0.52
595
5117
15
44
3.43
4.47
1.1
1.1
—
—
—
0
0
42
791
0.52
4.36
2.0
3.1
18.11
5408.57
u/ml
0.92
34
681
171
2309
0.71
4.23
1.3
1.3
13.39
14.68
u/ml
0.08
68
750
10
17
5.91
4.13
1.2
1.2
—
—
—
0
0
92
1385
0.65
4.06
1.3
1.3
—
—
—
0
0
10
18
5.58
3.97
1.1
1.2
—
—
—
0
0
211
2718
0.75
3.83
1.6
1.5
2.85
2.76
g/l
0.16
121
1542
1332
14084
0.82
3.80
4.8
5.4
1.38
1.44
mmol/l
5.46
1209
12584
1387
14605
0.81
3.79
5.8
6.5
2.41
2.45
mmol/l
1.15
1269
13117
22
90
2.46
3.72
2.4
1.6
0.71
3.31
u/field
2.68
14
61
8
251
0.32
3.71
5.6
4.0
36.13
35.77
u/ml
—
8
244
9
269
0.33
3.69
1.2
1.1
—
—
—
0
0
8
12
6.69
3.67
1.1
1.2
—
—
—
0
0
189
2454
0.74
3.63
1.3
1.3
50.93
38.45
iu/ml
0.38
55
773
11
25
4.42
3.62
2.5
2.4
38.64
40.00
umol/l
0.07
11
20
1242
11617
1.20
3.48
4.3
4.3
15.75
15.23
pmol/l
9.92
1124
10289
215
1675
1.32
3.47
2.5
2.6
0.48
0.52
e6/l
0.14
210
1614
287
2325
1.28
3.45
2.8
3.5
5.84
5.83
kpa
0.02
278
2259
627
5522
1.20
3.44
4.0
3.6
0.56
0.52
e6/l
0.12
504
4198
1351
14220
0.83
3.40
4.9
5.5
4.24
4.34
mmol/l
2.85
1235
12816
187
1432
1.34
3.40
2.5
3.0
131.55
126.02
g/l
3.56
182
1392
410
3482
1.23
3.24
3.5
3.3
1.52
1.25
e6/l
0.54
247
1936
579
6521
0.84
3.10
4.0
4.2
11.47
8.76
mg/mmol
0.52
428
4110
114
820
1.42
3.06
1.3
1.4
83.20
56.23
au/ml
—
5
60
1068
9921
1.18
3.02
5.9
7.3
1.21
1.21
mmol/l
1.67
937
8487
257
3132
0.79
3.02
2.4
2.7
19.66
21.26
%
1.29
231
2887
7
12
5.85
3.02
1.7
2.1
19.19
14.57
umol/l
—
7
12
65
418
1.57
3.01
1.7
2.4
25.72
33.94
umol/l
2.59
54
362
9
21
4.30
2.99
1.0
1.2
—
—
—
0
0
9
242
0.37
2.92
2.8
3.9
—
—
—
0
0
336
3961
0.82
2.90
3.9
4.5
338.41
347.30
ng/l
0.03
288
3526
10
27
3.72
2.88
1.0
1.1
—
—
—
0
0
274
2256
1.25
2.88
2.8
3.5
2.01
1.86
mmol/l
0.30
241
1931
279
3344
0.81
2.82
2.3
2.7
2.23
2.24
g/l
0.05
251
3060
1367
14301
0.84
2.81
7.7
7.6
42.11
40.79
mmol/mol
5.41
1269
13015
48
760
0.62
2.73
1.5
1.2
200.11
211.42
u/ml
0.06
43
694
1558
15000
1.22
2.72
23.5
21.0
28.42
28.49
mg/l
0.03
1420
12965
16
66
2.44
2.71
2.9
2.2
53.18
48.59
umol/l
0.20
11
53
53
810
0.64
2.59
2.2
2.7
—
—
—
0
0
75
1067
0.69
2.57
5.0
4.1
1.02
1.02
ratio
1.28
63
972
130
1692
0.75
2.56
2.6
2.4
31.44
36.67
u/l
1.08
110
1393
381
4389
0.83
2.55
4.0
3.6
0.36
0.06
0.52
11
184
406
4650
0.84
2.55
2.5
3.0
356.59
362.54
umol/l
0.47
339
3943
1397
14554
0.85
2.55
5.7
5.9
6.25
6.14
mmol/l
2.46
1266
12913
627
5641
1.17
2.54
2.3
2.6
59.55
76.13
u/l
0.57
571
5173
213
2596
0.80
2.50
2.8
3.9
231.65
251.43
u/l
1.31
194
2443
20
393
0.50
2.49
1.3
1.5
33.47
30.76
g/l
0.37
20
359
14
309
0.45
2.43
1.4
1.4
22136.13
76061.73
e6/l
—
8
173
125
1622
0.75
2.42
1.9
2.0
142.81
158.86
ug/g
0.35
96
1275
26
466
0.55
2.42
1.6
1.5
—
—
—
0
0
5
158
0.31
2.42
1.4
1.5
—
—
—
0
0
385
4403
0.84
2.36
4.8
4.2
1.54
0.05
estimate
0.47
162
1516
14
59
2.38
2.29
1.3
1.1
1.17
1.28
u/l
—
7
31
14
59
2.38
2.29
1.3
1.1
733.40
91.85
ng/l
—
5
13
154
1916
0.79
2.18
1.7
2.1
0.21
0.20
g/l
1.34
135
1770
13
56
2.33
2.05
1.0
1.2
0.54
0.48
ratio
—
7
32
8
194
0.41
2.04
1.0
1.1
1.50
1.60
g/l
—
8
178
583
6378
0.88
1.93
3.3
3.5
7.34
6.90
mmol/l
1.86
508
5240
0
50
0.00
1.88
0.0
2.8
—
618.88
—
0
50
7
22
3.19
1.88
1.0
1.0
—
—
—
0
0
104
806
1.31
1.84
1.9
2.1
647.80
793.16
ug/l
0.18
94
764
38
573
0.66
1.83
1.4
1.7
11.43
8.54
iu/ml
—
7
133
772
7178
1.13
1.81
2.7
3.5
1089.46
1858.92
ng/l
8.84
654
6348
25
414
0.60
1.81
1.2
1.3
—
—
—
0
0
137
1105
1.26
1.79
1.7
1.6
1.59
1.64
%
0.40
119
892
29
459
0.63
1.75
1.7
1.5
0.01
13.74
iu/ml
—
5
99
44
298
1.49
1.73
1.1
1.1
—
2.81
—
0
11
103
1303
0.78
1.71
1.4
1.3
—
—
—
0
0
32
204
1.58
1.65
1.9
1.5
—
—
—
0
0
87
1119
0.77
1.65
1.9
2.3
11.40
12.33
nmol/l
0.51
79
957
20
340
0.58
1.62
1.2
1.3
—
—
—
0
0
316
3566
0.86
1.62
2.2
2.7
10.53
11.70
umol/l
2.85
287
3294
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
8
172
0.46
1.58
1.3
1.5
—
—
—
0
0
8
172
0.46
1.58
1.3
1.5
—
—
—
0
0
8
172
0.46
1.58
1.3
1.5
—
—
—
0
0
11
222
0.49
1.58
1.1
1.1
—
4.86
—
0
7
106
1318
0.79
1.55
1.4
1.4
—
—
—
0
0
188
1596
1.20
1.53
1.7
1.6
—
—
—
0
0
5
125
0.40
1.50
1.4
1.2
—
—
—
0
0
24
380
0.63
1.49
1.5
2.4
207.75
211.84
%
0.10
24
357
116
1418
0.81
1.47
4.0
3.9
5.17
5.17
kpa
0.02
106
1350
572
5280
1.12
1.47
4.7
5.2
21.78
22.18
%
0.26
308
2902
13
240
0.54
1.44
2.0
1.4
—
—
—
0
0
13
238
0.54
1.40
2.0
1.4
—
—
—
0
0
10
46
2.18
1.40
1.1
1.4
—
—
—
0
0
13
236
0.55
1.37
2.0
1.4
—
—
—
0
0
13
236
0.55
1.37
2.0
1.4
—
—
—
0
0
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
60
453
1.34
1.34
1.5
1.4
—
—
—
0
0
60
453
1.34
1.34
1.4
1.4
—
—
—
0
0
0
41
0.00
1.31
0.0
1.0
—
277.46
—
0
28
17
282
0.60
1.30
2.5
2.4
18.00
23.81
mg/l
—
7
97
9
43
2.10
1.30
1.0
1.0
2032.78
1497.88
miu/ml
—
9
43
14
244
0.57
1.29
1.9
1.4
—
—
—
0
0
1513
15481
0.89
1.29
11.6
13.5
23.68
23.90
u/l
0.18
1450
14880
5
18
2.78
1.28
1.0
1.1
—
—
—
0
0
14
243
0.57
1.28
1.9
1.4
—
—
—
0
0
343
3786
0.89
1.27
3.0
3.6
0.72
0.82
ug/l
1.64
250
2763
57
744
0.76
1.26
5.0
4.1
25.36
24.89
mmol/l
0.52
49
677
18
107
1.69
1.26
1.7
3.8
2.39
0.93
%
1.34
18
107
685
7277
0.91
1.24
2.7
3.1
132.36
152.08
ug/l
1.81
619
6605
103
1239
0.82
1.16
2.7
2.9
10.27
10.90
g/l
1.09
94
1123
1240
11999
1.10
1.14
3.9
4.6
15.56
15.32
mm/h
0.19
1126
11021
24
354
0.67
1.13
1.3
1.3
—
65.00
—
0
8
180
1570
1.16
1.12
1.7
1.8
—
—
—
0
0
24
352
0.68
1.10
1.9
1.6
—
—
—
0
0
12
66
1.82
1.09
2.0
2.0
13.31
16.60
nmol/l
1.23
12
59
31
432
0.71
1.08
1.7
1.6
—
—
—
0
0
905
9444
0.92
1.05
8.0
9.1
4.59
4.38
e9/l
1.66
781
8079
18
114
1.58
1.02
1.4
1.9
—
—
—
0
0
276
3041
0.89
1.00
1.2
1.2
1.38
1.49
u/ml
0.07
90
746
5
109
0.46
1.00
1.2
1.0
—
—
—
0
0
96
1143
0.83
1.00
1.4
1.7
1.68
1.52
g/l
1.16
83
987
27
189
1.43
0.99
2.3
2.1
3.08
1.37
u/field
0.63
13
94
31
223
1.40
0.98
1.7
1.3
287.15
272.82
mosm/kgh2o
1.68
26
158
71
869
0.81
0.98
3.9
3.2
55.35
119.74
mg/l
0.51
61
742
17
260
0.65
0.97
1.5
1.5
102.06
334.34
pmol/l
2.66
17
254
10
54
1.86
0.96
1.0
1.1
—
—
—
0
0
0
31
0.00
0.96
0.0
1.3
—
—
—
0
0
23
328
0.70
0.94
1.8
1.4
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
39
508
0.76
0.91
4.8
3.6
7.10
7.82
mmol/l
1.47
39
494
150
1704
0.87
0.90
2.6
3.7
73.34
97.67
ng/l
5.02
125
1422
72
868
0.82
0.88
3.9
3.2
33.78
78.27
mg/l
1.53
63
743
13
79
1.65
0.88
1.0
1.2
—
—
—
0
0
58
467
1.25
0.88
1.9
2.4
138.60
84.26
ug/min
0.39
27
268
104
1211
0.85
0.87
4.1
3.7
1.97
2.14
mmol/l
0.17
72
886
6
30
2.00
0.87
1.0
1.4
2.25
2.07
umol/l
—
6
24
6
30
2.00
0.87
1.2
1.2
—
—
—
0
0
10
168
0.59
0.86
1.2
1.3
—
—
—
0
0
21
299
0.70
0.86
1.9
1.4
—
—
—
0
0
38
291
1.31
0.85
1.5
1.3
—
—
—
0
0
6
115
0.52
0.82
3.0
3.7
—
—
—
0
0
14
212
0.66
0.80
1.1
1.1
167.80
310.32
u/ml
—
5
110
54
662
0.81
0.79
3.1
3.5
0.78
0.82
nmol/l
0.34
49
540
73
867
0.84
0.78
1.8
2.0
—
—
—
0
0
0
27
0.00
0.77
0.0
1.3
—
—
—
0
0
8
134
0.60
0.73
1.0
1.1
145.25
114.37
%
—
8
121
8
134
0.60
0.73
1.0
1.1
—
—
—
0
0
43
532
0.80
0.71
1.6
1.3
—
—
—
0
0
22
297
0.74
0.69
1.6
1.4
—
—
—
0
0
7
118
0.59
0.68
1.3
1.3
—
—
—
0
0
7
118
0.59
0.68
1.3
1.3
—
—
—
0
0
50
604
0.82
0.67
4.2
3.4
1.91
1.68
mmol/l
0.42
50
589
26
197
1.32
0.66
1.2
1.6
—
—
—
0
0
1587
15656
1.08
0.64
28.5
26.1
139.55
139.49
mmol/l
0.36
1544
15336
1588
15671
1.08
0.62
28.4
26.4
3.98
4.02
mmol/l
5.47
1544
15328
27
208
1.30
0.62
3.2
3.3
12.14
11.08
index
—
7
105
10
63
1.59
0.61
1.0
1.4
34.62
28.79
umol/l
—
10
58
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
70
810
0.86
0.59
2.3
2.5
0.41
0.35
iu/ml
0.69
33
446
976
9495
1.06
0.59
4.1
6.5
11.67
12.63
umol/l
1.12
919
9029
0
23
0.00
0.58
0.0
15.7
—
5.31
—
0
23
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
7
113
0.62
0.58
1.1
1.1
—
—
—
0
0
6
35
1.72
0.57
1.0
1.2
0.28
0.30
g/l
—
6
27
59
689
0.85
0.57
1.3
1.1
79.18
107.63
u/ml
0.27
26
222
33
265
1.25
0.56
5.4
5.6
8.30
7.51
mmol/l
0.35
23
225
19
141
1.35
0.56
1.9
1.7
7.86
8.22
mmol/l
0.16
19
141
43
516
0.83
0.56
1.2
1.3
—
—
—
0
0
15
107
1.41
0.55
5.9
5.5
10.77
24.21
u/ml
—
6
34
876
9007
0.95
0.54
3.1
3.3
49.28
57.21
u/l
1.79
802
8184
54
460
1.18
0.53
1.4
1.5
—
—
—
0
0
12
170
0.70
0.53
2.3
1.6
2.80
4.76
mg/l
5.15
12
165
52
442
1.18
0.53
1.2
1.2
—
—
—
0
0
56
650
0.86
0.51
1.6
1.8
35.09
38.81
u/l
0.75
45
557
69
788
0.87
0.51
3.4
3.1
3.15
3.74
ratio
0.15
43
470
19
144
1.32
0.50
1.3
1.3
17.93
27.92
%
0.77
14
86
64
558
1.15
0.49
3.5
3.6
0.95
1.88
index
1.09
21
284
52
446
1.17
0.49
1.2
1.2
—
—
—
0
0
7
45
1.56
0.49
2.1
2.5
—
—
—
0
0
34
280
1.22
0.49
1.6
1.7
4.20
4.14
mmol/24h
0.04
29
240
144
1323
1.10
0.47
4.6
7.3
24.84
24.85
mmol/l
0.02
144
1316
7
48
1.46
0.46
2.1
2.5
—
—
—
0
0
49
568
0.86
0.46
1.0
1.1
—
—
—
0
0
5
85
0.59
0.45
1.2
1.2
—
—
—
0
0
43
501
0.85
0.43
1.7
1.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
14.40
—
0
10
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
17
0.00
0.40
0.0
1.2
—
4761.64
—
0
11
21
260
0.81
0.40
1.8
1.5
—
—
—
0
0
7
102
0.69
0.39
1.0
1.2
111.71
94.69
u/l
—
7
87
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
187
1990
0.93
0.38
4.5
6.2
9.99
11.55
mmol/l
2.14
175
1892
36
420
0.85
0.38
4.0
3.9
29.72
29.51
mg/l
0.01
24
297
5
36
1.39
0.38
1.0
1.0
88.80
98.41
%
—
5
27
109
1004
1.09
0.36
1.7
1.8
1.05
2.49
ug/l
1.49
93
861
44
501
0.88
0.35
1.5
1.6
20117.25
15958.15
e6/l
0.19
28
348
73
804
0.90
0.34
1.8
1.9
—
—
—
0
0
17
136
1.25
0.33
2.5
2.5
—
—
—
0
0
211
2220
0.94
0.32
2.0
2.5
67.39
67.85
e9/l
0.07
156
1656
90
977
0.92
0.32
2.5
2.4
3.68
3.74
g/l
0.17
78
878
32
370
0.86
0.32
1.3
1.2
15.70
42.69
u/l
2.80
27
322
1590
15776
1.05
0.31
29.8
28.6
82.98
85.67
umol/l
2.21
1547
15536
47
418
1.13
0.31
5.9
6.0
105.54
105.09
mmol/l
0.29
41
374
1405
13906
1.04
0.31
5.8
5.5
1.98
2.07
mu/l
1.79
1294
12470
17
138
1.23
0.30
1.4
1.4
—
—
—
0
0
31
356
0.87
0.29
1.5
1.4
—
—
—
0
0
8
108
0.74
0.29
2.0
1.5
—
—
—
0
0
21
248
0.85
0.28
1.9
1.5
—
—
—
0
0
91
979
0.93
0.28
2.5
2.4
7.64
7.48
g/l
0.33
78
878
91
979
0.93
0.28
2.5
2.4
4.23
4.18
g/l
0.30
78
880
8
64
1.25
0.27
2.0
2.7
4.83
4.96
kpa
—
8
64
8
64
1.25
0.27
2.0
2.7
10.64
9.82
kpa
—
8
64
109
1021
1.07
0.27
4.3
4.2
1.43
1.52
%
0.95
103
967
14
171
0.82
0.26
2.1
1.5
—
—
—
0
0
26
299
0.87
0.26
1.1
1.3
—
—
—
0
0
11
138
0.80
0.25
1.2
1.3
—
—
—
0
0
9
74
1.22
0.25
1.9
1.8
98.56
51.25
ug/l
—
9
69
52
570
0.91
0.25
1.4
1.5
—
—
—
0
0
562
5498
1.03
0.24
2.3
2.4
3.21
3.02
mg/l
1.01
476
4686
11
136
0.81
0.23
1.9
1.5
106.96
95.86
ng/l
0.10
11
136
15
179
0.84
0.23
1.3
1.5
35.17
33.96
ng/l
0.03
15
179
668
6560
1.03
0.22
5.1
6.4
4.51
4.49
ug/l
0.01
584
5802
7
93
0.75
0.22
2.6
1.3
—
—
—
0
0
7
93
0.75
0.22
2.6
1.3
—
—
—
0
0
7
95
0.74
0.22
1.0
1.3
17.29
24.89
u/l
—
7
79
49
449
1.09
0.21
1.4
1.5
0.25
0.30
mg/l
0.35
28
182
85
798
1.07
0.21
3.2
3.1
4.34
4.32
pmol/l
0.08
72
688
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
6.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
1.22
—
0
8
0
13
0.00
0.21
0.0
1.6
—
0.97
—
0
8
0
13
0.00
0.21
0.0
1.6
—
1.01
—
0
8
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
777
7657
1.02
0.20
2.2
2.4
78.54
79.98
nmol/l
0.70
665
6641
207
1998
1.04
0.20
2.6
2.6
67.00
66.01
g/l
1.25
185
1815
6
50
1.20
0.19
1.7
1.2
1.11
1.09
ratio
—
6
39
1590
15816
1.03
0.19
33.1
31.7
91.50
91.98
fl
3.66
1550
15565
16
186
0.86
0.19
1.0
1.0
—
—
—
0
0
1590
15817
1.03
0.19
33.2
31.8
247.35
238.87
e9/l
5.56
1543
15417
1590
15818
1.03
0.19
33.5
32.3
39.34
39.03
%
1.86
1551
15559
1590
15818
1.03
0.19
33.2
31.7
4.33
4.33
e12/l
0.03
1539
15347
1590
15820
1.03
0.18
33.5
32.0
130.30
130.68
g/l
0.48
1553
15576
1590
15821
1.03
0.18
33.2
31.8
7.36
7.03
e9/l
1.90
1544
15346
366
3578
1.03
0.17
1.6
1.6
1.68
1.56
mg/l
0.20
295
2823
201
2076
0.96
0.17
4.8
3.9
—
—
—
0
0
52
558
0.93
0.17
1.4
1.5
294.33
267.19
ug/g
0.39
27
340
37
403
0.92
0.17
1.4
1.9
25.51
12.98
mg/l
0.43
30
366
47
506
0.93
0.17
1.6
1.5
—
—
—
0
0
49
526
0.93
0.17
2.9
2.4
132.55
125.86
g/l
1.04
40
415
86
902
0.95
0.15
2.5
2.5
2.95
2.99
g/l
0.12
73
802
1299
12907
1.02
0.15
6.2
8.5
80.03
83.03
u/l
0.98
1215
12148
22
244
0.90
0.14
1.1
1.1
—
—
—
0
0
19
169
1.13
0.14
1.1
1.1
—
23.13
—
0
20
56
528
1.06
0.14
1.2
1.2
—
—
—
0
0
8
99
0.81
0.13
1.9
1.4
149.38
93.11
umol/l
—
8
99
36
335
1.08
0.13
1.8
1.7
4.46
22.44
iu/l
0.48
11
126
20
221
0.90
0.12
2.1
1.2
0.79
8.88
nmol/l
0.49
20
207
43
404
1.07
0.12
1.5
1.4
—
—
—
0
0
65
679
0.96
0.11
2.9
2.5
0.00
0.00
g/l
-0.00
54
598
87
840
1.04
0.10
3.1
2.5
0.64
1.31
g/l
2.08
73
708
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
20
217
0.92
0.09
1.8
1.4
—
—
—
0
0
67
695
0.96
0.09
2.6
2.4
0.04
0.03
g/l
0.02
60
623
22
204
1.08
0.08
2.2
2.9
—
—
—
0
0
5
62
0.81
0.08
2.0
1.8
2.68
5.17
nmol/l
—
5
51
7
84
0.83
0.07
1.0
1.1
—
—
—
0
0
278
2745
1.01
0.07
3.8
5.4
1.03
1.04
mmol/l
0.23
253
2530
7
85
0.82
0.07
2.0
1.5
—
—
—
0
0
7
85
0.82
0.07
1.0
1.2
8.94
10.23
mmol/l
—
7
78
8
90
0.89
0.06
3.0
2.1
—
—
—
0
0
84
862
0.97
0.06
2.6
2.5
9.95
10.52
g/l
0.89
71
756
19
177
1.07
0.06
1.2
1.2
5222.64
146874.38
e6/l
1.62
14
115
20
187
1.07
0.06
1.2
1.7
—
—
—
0
0
10
111
0.90
0.06
1.9
1.4
—
—
—
0
0
161
1635
0.98
0.06
4.1
3.8
1.23
1.22
mmol/l
0.56
145
1395
118
1202
0.98
0.05
5.8
8.9
16.63
15.67
%
3.48
113
1157
12
131
0.92
0.05
1.8
1.4
—
—
—
0
0
34
354
0.96
0.05
1.5
1.4
—
—
—
0
0
14
150
0.93
0.04
1.1
1.1
—
1.40
—
0
8
14
149
0.94
0.03
1.1
1.2
109.50
99.81
pmol/l
0.31
14
149
21
201
1.05
0.03
1.1
1.3
279.67
267.05
pmol/l
0.09
12
166
153
1542
0.99
0.02
2.1
2.1
371.63
390.25
nmol/l
0.58
136
1403
327
3258
1.00
0.01
2.2
2.9
0.82
0.81
mmol/l
0.16
300
3031
23
237
0.97
0.01
1.3
1.3
—
—
—
0
0
43
437
0.98
0.01
5.1
5.0
4.97
5.06
kpa
0.43
43
430
11
115
0.96
0.00
1.8
1.4
—
—
—
0
0
14
142
0.99
0.00
2.2
1.3
—
—
—
0
0
14
143
0.98
0.00
2.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
2.63
—
0
8
0
8
0.00
0.00
0.0
1.1
—
33.62
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.00
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
322
3220
1.00
-0.00
4.0
3.4
3.28
2.09
e6/l
1.00
159
1663
0
7
0.00
-0.00
0.0
2.3
—
24.21
—
0
7
6
60
1.00
-0.00
1.7
1.3
18.95
32.80
u/l
—
6
49
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
5.96
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
56.56
—
0
7
6
60
1.00
-0.00
2.2
1.4
134.17
153.39
mmol/24h
—
6
60
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.0
1.6
39.66
39.56
g/l
—
8
87
6
62
0.97
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_HCNP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCNP | 2.238 [2.01, 2.49] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.32 |
During the follow-up period (1.1.1998 — 31.12.2019), 1631 out of 3345 females with G6_HCNP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCNP | 2.381 [2.07, 2.74] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 1722 out of 3293 males with G6_HCNP died.
Mortality risk
Mortality risk for people of age
years, who have G6_HCNP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.211% | 0.473% |
| 5 | 1.38% | 2.537% |
| 10 | 3.1% | 6.356% |
| 15 | 6.083% | 11.522% |
| 20 | 11.154% | 18.816% |
Relationships between endpoints
↥Index endpoint: G6_HCNP – Normal-pressure hydrocephalus
GWS hits: 14
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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