Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
40758310	s-he4	pmol/l (pmol/l)	7681	10779	0.00%
40758310	p-he4	pmol/l (pmol/l)	1558	2092	0.14%
40758310	s-he4	— (—)	362	404	100.00%	Distribution not available
40758310	he4proteiini	pmol/l (pmol/l)	10	10	0.00%	Distribution not available
40758310	s-he4ihmisenepididymaalinenproteiini4	pmol/l (pmol/l)	7	7	0.00%	Distribution not available
40758310	p-he4	— (—)	5	5	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Serous carcinoma of ovary, excluding all cancers (controls excluding all cancers)

492

260

31.54

307.65

2.0

1.4

619.25

85.49

pmol/l

16.38

469

252

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

1827

1569

14.81

307.65

1.6

1.4

365.82

79.25

pmol/l

31.11

1779

1537

malignant neoplasm of female genital organs

1371

1390

12.58

307.65

1.6

1.4

360.22

131.54

pmol/l

13.29

1327

1353

Malignant neoplasm of ovary

617

484

19.94

307.65

1.8

1.5

415.21

211.12

pmol/l

3.29

586

476

Endometriosis

1604

1609

6.37

307.65

1.6

1.4

78.83

228.15

pmol/l

10.54

1558

1565

Ascites

359

334

12.19

307.65

1.6

1.4

678.05

147.92

pmol/l

10.44

340

328

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

972

527

30.02

307.65

1.8

1.4

453.30

74.51

pmol/l

24.16

934

512

Serous carcinoma of ovary

492

368

22.08

307.65

2.0

1.4

619.25

233.52

pmol/l

5.66

469

362

Endometriosis of pelvic peritoneum

714

1117

6.84

307.65

1.5

1.4

85.41

191.24

pmol/l

4.70

696

1087

Malignant neoplasm of corpus uteri

549

785

8.36

307.65

1.4

1.5

209.74

228.78

pmol/l

0.18

542

763

Endometriosis ASRM stages 3,4

1182

3228

4.00

307.65

1.6

1.4

61.26

148.39

pmol/l

12.99

1156

3140

Neoplasms

1703

2482

3.76

307.65

1.6

1.3

120.85

58.03

pmol/l

5.27

1667

2388

Malignant neoplasm of corpus uteri, excluding all cancers (controls excluding all cancers)

703

687

12.47

307.65

1.3

1.4

195.22

82.48

pmol/l

4.70

693

669

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

2094

4680

2.71

307.65

1.5

1.4

199.32

64.74

pmol/l

19.34

2053

4572

Any gastric operation

1925

3051

3.24

307.65

1.5

1.3

143.91

68.18

pmol/l

7.67

1872

2977

GASTRO-related operations

1925

3051

3.24

307.65

1.5

1.3

143.91

68.18

pmol/l

7.67

1872

2977

Benign neoplasm of ovary

884

1484

6.65

307.65

1.4

70.07

75.49

pmol/l

0.51

879

1448

Exclusions for E4_PCOS_CONSORTIUM

2658

5341

3.26

307.65

1.5

1.4

155.61

95.54

pmol/l

5.71

2597

5197

Other symptoms and signs involving the digestive system and abdomen

1077

1386

8.88

307.65

1.7

1.4

162.38

119.23

pmol/l

1.89

1049

1353

Endometriosis of ovary

1056

1210

9.85

307.65

1.6

1.3

55.76

219.61

pmol/l

12.23

1032

1173

Malignant neoplasm of other and unspecified female genital organs, excluding all cancers (controls excluding all cancers)

375

191

32.65

307.65

1.7

1.5

812.54

67.29

pmol/l

19.09

362

186

Benign neoplasm of ovary

884

2169

4.50

307.65

1.4

1.5

70.07

188.87

pmol/l

13.52

879

2109

Unspecified/other endometriosis

436

546

8.77

307.65

1.5

1.4

68.68

169.50

pmol/l

3.18

418

531

Ovarian cyst

3122

1646

12.69

307.65

1.5

1.4

72.18

224.62

pmol/l

12.40

3045

1599

Noninflammatory disorders of female genital tract

1294

1705

3.96

307.65

1.4

111.11

219.11

pmol/l

4.97

1257

1652

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

2095

4680

2.71

307.65

1.5

1.4

199.26

64.74

pmol/l

19.34

2054

4572

Malignant neoplasm, wide definition for exclusion

2094

4680

2.71

307.65

1.5

1.4

199.32

64.74

pmol/l

19.34

2053

4572

Polyp of the female genital tract

978

1454

4.09

282.57

1.4

116.97

247.67

pmol/l

6.62

961

1414

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

846

1917

4.01

277.06

1.6

1.4

386.73

76.29

pmol/l

14.32

826

1877

Benign neoplasms

1553

3082

2.91

274.36

1.5

1.4

94.84

58.13

pmol/l

2.82

1516

2981

Any event in cancer register

2135

5296

2.44

273.79

1.5

1.4

175.97

81.81

pmol/l

11.60

2086

5171

Postmenopausal bleeding

888

1170

4.39

271.73

1.3

1.4

130.95

284.46

pmol/l

6.56

873

1139

Female infertility

920

1453

4.08

271.33

1.4

95.65

196.77

pmol/l

4.83

899

1416

Female infertility, cervigal, vaginal, other or unspecified origin

835

1409

4.14

258.73

1.5

1.4

95.68

195.79

pmol/l

4.38

817

1376

Congenital malformations of ovaries, fallopian tubes and broad ligaments

432

744

6.91

248.42

1.4

1.5

48.70

138.71

pmol/l

2.97

419

730

Malignant neoplasm

1959

4898

2.42

247.05

1.5

1.4

193.14

85.28

pmol/l

12.66

1914

4792

Excessive, frequent and irregular menstruation

1029

1688

3.50

239.46

1.5

1.4

103.72

220.62

pmol/l

6.74

993

1637

Leiomyoma of uterus

1516

3220

2.76

238.38

1.5

1.4

102.54

66.85

pmol/l

2.78

1483

3146

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

424

736

6.06

234.18

1.6

1.4

559.75

74.93

pmol/l

9.80

412

716

Congenital malformations of genital organs

495

1047

5.20

220.96

1.4

1.5

55.65

118.29

pmol/l

2.64

479

1024

Appendectomy

1571

6626

2.34

204.45

1.5

1.4

188.34

105.21

pmol/l

6.61

1535

6466

Pain and other conditions associated with female genital organs and menstrual cycle

545

1290

4.22

195.47

1.5

1.4

63.71

169.72

pmol/l

9.38

520

1253

Menorrhagia

879

1547

3.24

182.37

1.5

1.4

128.31

236.68

pmol/l

4.12

858

1503

Symptoms and signs involving the digestive system and abdomen

1745

4061

2.18

167.22

1.5

1.4

159.55

103.34

pmol/l

3.51

1692

3970

Benign neoplasms

1814

4854

2.12

165.99

1.5

1.4

100.75

136.25

pmol/l

2.33

1774

4707

Genitourinary diseases

693

1009

3.48

156.82

1.4

134.59

179.33

pmol/l

0.82

680

979

Endometriosis ASRM stages 1,2

733

2633

2.96

149.12

1.5

1.4

84.69

122.86

pmol/l

1.33

711

2568

Adenomyosis (Endometriosis of uterus)

380

927

4.31

140.93

1.5

1.4

80.27

268.79

pmol/l

8.06

369

902

Endometriosis diagnosis and infertility diagnosis occurring together

501

1523

3.57

136.97

1.5

87.16

115.44

pmol/l

0.57

491

1491

Abdominal and pelvic pain

1620

4061

2.03

129.72

1.5

1.4

136.03

103.34

pmol/l

1.38

1572

3970

Other medical care

760

2948

2.58

123.27

1.6

1.4

379.78

134.19

pmol/l

8.47

727

2884

Complications of procedures, not elsewhere classified

1532

7012

1.92

117.46

1.5

1.4

114.45

130.61

pmol/l

0.95

1489

6846

Endometroid carcinoma of ovary, excluding all cancers (controls excluding all cancers)

102

19.93

116.45

1.9

1.4

213.97

59.15

pmol/l

4.05

Leiomyoma of uterus

1816

5681

1.87

115.13

1.4

111.94

148.36

pmol/l

2.25

1776

5547

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

354

951

3.83

113.92

1.5

1.4

267.03

75.65

pmol/l

4.09

346

924

Deep endometriosis

403

1201

3.62

113.54

1.6

1.4

65.53

164.64

pmol/l

5.58

396

1168

Other noninflammatory disorders of uterus, except cervix

507

1105

3.24

112.70

1.5

1.4

168.64

283.01

pmol/l

2.73

497

1072

Complications of surgical and medical care, not elsewhere classified

1786

7164

1.81

111.06

1.5

1.4

129.45

128.87

pmol/l

0.02

1738

6994

Benign leiomyoma with endometriosis

436

1406

3.25

106.63

1.5

1.3

81.18

77.18

pmol/l

0.16

421

1374

Hernia of abdominal wall, postoperative

279

676

4.23

103.58

1.5

1.3

209.93

91.56

pmol/l

2.12

273

660

Carcinoma in situ of endometrium

33.63

92.19

1.2

1.4

76.57

57.65

pmol/l

1.48

Other abnormal uterine and vaginal bleeding

472

1192

2.90

89.13

1.4

169.37

266.60

pmol/l

1.66

459

1151

Complications of medical and surgical care

1309

6914

1.82

87.44

1.5

1.4

121.51

134.76

pmol/l

0.62

1278

6745

Salpingitis and oophoritis

594

2524

2.47

85.46

1.5

1.4

89.94

147.96

pmol/l

4.32

589

2466

Dysplasia of cervi uteri

463

1330

2.76

81.71

1.4

85.60

210.35

pmol/l

5.82

455

1293

Intestinal stricture

501

2005

2.56

80.64

1.7

1.4

233.82

180.22

pmol/l

1.37

485

1953

Inflammatory diseases of female pelvic organs

1653

7547

1.68

79.27

1.5

1.4

101.82

130.36

pmol/l

1.41

1610

7353

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1062

5748

1.87

77.38

1.5

1.4

116.48

144.21

pmol/l

1.71

1040

5610

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

984

5438

1.84

67.89

1.5

1.4

115.96

144.10

pmol/l

1.62

963

5303

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

212

606

3.59

62.49

1.5

1.4

227.48

73.03

pmol/l

4.57

207

588

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

478

1631

2.31

59.75

1.4

164.72

80.67

pmol/l

3.65

469

1595

Other menopausal disorders

507

1312

2.27

55.83

1.3

1.4

117.65

251.17

pmol/l

3.73

495

1281

Abnormal findings on diagnostic imaging of other body structures

297

1110

2.78

55.74

1.4

1.5

120.11

166.06

pmol/l

1.38

286

1084

Paralytic ileus and intestinal obstruction

390

1708

2.33

51.50

1.7

1.4

209.25

181.59

pmol/l

0.54

376

1663

Oxycodone

510

2398

2.09

51.43

1.6

1.4

354.94

145.91

pmol/l

5.32

493

2341

Congenital malformations, deformations and chromosomal abnormalities

1039

6045

1.67

50.98

1.4

78.93

113.02

pmol/l

3.72

1008

5888

Persons encountering health services for other counselling and medical advice, not elsewhere classified

1757

6745

1.50

49.96

1.4

136.22

123.25

pmol/l

0.63

1709

6578

Benign leiomyoma with endometriosis

436

2053

2.20

49.15

1.5

81.18

196.25

pmol/l

8.97

421

1997

Procreative management

615

2719

1.94

49.12

1.5

1.4

111.71

116.02

pmol/l

0.09

602

2652

Other or unspecified ileus, impaction or obstruction

271

1044

2.65

47.41

1.6

1.4

244.92

192.26

pmol/l

0.81

261

1016

Follow-up examination after treatment for conditions other than malignant neoplasms

902

3469

1.73

47.16

1.4

91.07

131.95

pmol/l

3.51

882

3401

Female genital prolapse

480

1353

2.08

43.01

1.5

1.4

139.96

261.28

pmol/l

3.18

470

1317

Hydronephrosis

195

675

2.97

42.15

1.7

1.4

289.60

167.08

pmol/l

1.45

190

660

Anaemias

455

1491

2.06

41.24

1.6

1.4

128.21

56.71

pmol/l

3.30

445

1455

Pain in joint

859

3437

1.67

40.31

1.4

118.01

138.11

pmol/l

0.49

834

3354

Nausea and vomiting

367

1715

2.14

39.59

1.5

1.4

185.14

115.83

pmol/l

2.39

357

1670

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

882

3587

1.63

37.19

1.4

139.66

69.00

pmol/l

6.14

859

3514

Postmenopausal atrophic vaginitis

406

1192

2.09

37.05

1.4

126.99

280.13

pmol/l

5.68

393

1163

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

881

3587

1.63

36.98

1.4

139.79

69.00

pmol/l

6.15

858

3514

Cystitis

1543

6612

1.44

36.50

1.4

117.89

119.75

pmol/l

0.06

1498

6451

Medical treatment for female infertility

577

3302

1.79

36.09

1.4

53.98

77.42

pmol/l

2.63

564

3222

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

596

1651

1.83

35.97

1.4

147.93

93.56

pmol/l

1.07

581

1619

Other female pelvic inflammatory diseases

422

2213

1.96

35.37

1.5

1.4

89.46

155.07

pmol/l

3.54

407

2149

In situ neoplasms

491

2577

1.84

34.51

1.4

119.51

69.44

pmol/l

2.76

479

2516

Parasetamol

1220

4194

1.49

34.05

1.5

1.4

127.80

104.52

pmol/l

0.70

1184

4095

Irregular menses

1168

6492

1.48

33.22

1.4

86.58

112.37

pmol/l

1.38

1141

6324

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

596

2861

1.72

32.00

1.4

118.18

72.50

pmol/l

3.32

583

2803

Persons encountering health services for specific procedures and health care

1628

7308

1.39

31.84

1.5

1.4

214.88

102.41

pmol/l

8.14

1570

7144

Benign neoplasm of colon, rectum, anus and anal canal

586

2450

1.72

31.59

1.4

152.24

72.87

pmol/l

5.22

572

2392

Polycystic ovarian syndrome, consortium definition

1691

7502

1.38

30.53

1.4

119.21

126.43

pmol/l

0.23

1653

7303

Persons encountering health services in other circumstances, wide

1762

6755

1.36

29.57

1.5

1.4

135.13

123.36

pmol/l

0.57

1717

6588

Other diseases of intestines

1608

6839

1.38

29.36

1.5

1.4

131.81

116.47

pmol/l

0.58

1561

6670

Pain (limb, back, neck, head abdominally)

1016

3433

1.49

28.16

1.5

1.4

137.15

137.85

pmol/l

0.01

985

3348

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

805

4922

1.53

27.82

1.4

159.31

155.29

pmol/l

0.06

781

4796

Colectomy operation

226

1037

2.22

27.06

1.4

1.5

188.36

187.77

pmol/l

0.01

220

1008

Other diseases of urinary system

1581

6613

1.35

26.03

1.4

120.28

119.77

pmol/l

0.01

1537

6452

Benign neoplasm: Colon

477

2144

1.72

25.97

1.4

150.88

76.79

pmol/l

4.24

463

2094

Pleural effusion

163

663

2.50

25.72

1.6

1.5

468.34

206.76

pmol/l

2.64

154

645

Opioids

1567

6119

1.35

25.39

1.5

1.4

157.07

102.82

pmol/l

3.02

1519

5978

Persons encountering health services in other circumstances

567

3554

1.61

24.95

1.6

1.4

142.94

129.58

pmol/l

0.18

548

3458

Fever of other and unknown origin

750

4651

1.51

24.36

1.5

1.4

184.93

128.77

pmol/l

1.41

733

4526

Disorders of the thyroid gland

1451

7117

1.34

23.15

1.5

1.4

122.38

121.17

pmol/l

0.03

1415

6932

Malignant neoplasm of digestive organs

355

1977

1.78

22.99

1.4

1.5

149.97

213.97

pmol/l

1.35

348

1918

Examination and observation for other reasons

838

3497

1.47

22.36

1.5

1.4

141.64

131.20

pmol/l

0.15

815

3429

Pulmonary heart disease

343

1971

1.76

21.21

1.6

1.4

317.44

185.77

pmol/l

1.40

337

1911

Benign lipomatous neoplasm

320

1803

1.79

21.18

1.4

179.02

70.30

pmol/l

1.77

314

1760

Pulmonary embolism

343

1974

1.76

21.10

1.6

1.4

317.44

185.38

pmol/l

1.41

337

1914

DVT of lower extremities and pulmonary embolism

484

3042

1.60

20.90

1.5

1.4

280.79

169.06

pmol/l

1.75

471

2959

Misadventures to patients during surgical and medical care

221

1116

2.02

20.73

1.5

113.33

167.75

pmol/l

1.48

214

1089

Intestinal adhesions without obstruction

130

535

2.49

20.26

2.0

1.4

179.93

193.67

pmol/l

0.13

125

525

Ventral hernia

323

1858

1.76

20.02

1.5

1.4

178.64

165.06

pmol/l

0.17

316

1808

Hypothyroidism, other/unspecified

1405

7084

1.32

19.96

1.5

1.4

119.61

121.54

pmol/l

0.06

1370

6900

Follow-up examination after treatment for malignant neoplasms

168

777

2.21

19.94

2.1

1.4

231.19

191.89

pmol/l

0.27

163

759

Hypothyroidism (congenital or acquired)

457

1617

1.64

19.79

1.6

1.4

83.12

55.40

pmol/l

1.97

441

1574

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

371

2146

1.69

19.41

1.5

1.3

194.42

76.95

pmol/l

4.01

360

2099

Other disorders of urethra and urinary system

1132

6352

1.34

18.93

1.4

147.51

122.88

pmol/l

0.57

1097

6198

Hypothyreosis and Thyroxine purchase for inclusion criteria

1456

7434

1.30

18.86

1.5

1.4

126.33

125.05

pmol/l

0.03

1419

7245

Obesity due to excess calories

711

4973

1.44

18.81

1.4

132.93

117.39

pmol/l

0.45

681

4849

Pulmonary heart disease, diseases of pulmonary circulation

356

2139

1.68

18.75

1.6

1.5

339.62

183.72

pmol/l

1.69

350

2073

Hypothyroidism and >3 levothyroxin purchases

451

1616

1.62

18.70

1.6

1.4

83.49

55.40

pmol/l

1.98

435

1574

Hypothyroidism, levothyroxine purchases

451

1616

1.62

18.70

1.6

1.4

83.49

55.40

pmol/l

1.98

435

1574

Hernia of abdominal wall

497

3256

1.54

18.21

1.5

1.4

172.06

150.64

pmol/l

0.38

485

3162

General symptoms and signs

1636

6455

1.28

17.54

1.5

1.4

127.48

118.06

pmol/l

0.42

1599

6296

Diseases of peritoneum

155

735

2.15

17.35

1.5

181.22

197.20

pmol/l

0.12

150

720

Other benign neoplasms of skin

392

2428

1.60

16.91

1.5

1.4

128.97

70.48

pmol/l

2.68

385

2367

Medical observation and evaluation for suspected diseases and conditions

933

3498

1.37

16.89

1.6

1.4

130.18

131.25

pmol/l

0.02

906

3430

Medicines for HER+ breast cancer

708

4965

1.41

16.11

1.6

1.4

141.55

163.41

pmol/l

0.71

691

4847

Paracetamol of NSAID medication

209

544

1.95

15.78

1.4

117.03

104.67

pmol/l

0.09

203

527

Venous thromboembolism

629

4310

1.43

15.78

1.5

1.4

241.50

152.28

pmol/l

1.84

612

4201

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

503

2302

1.50

15.65

1.5

1.4

172.68

77.95

pmol/l

2.53

490

2248

Other nutritional deficiencies

974

7221

1.33

15.56

1.4

130.22

117.74

pmol/l

0.42

939

7051

Other pleural conditions

399

2.47

15.17

1.4

1.5

414.10

214.22

pmol/l

1.44

391

Benign neoplasm: Colon, unspecified

184

970

1.90

14.99

1.4

130.11

81.70

pmol/l

1.94

178

944

Obesity and other hyperalimentation

935

7031

1.33

14.84

1.4

132.34

118.95

pmol/l

0.44

902

6865

Obesity

931

7003

1.33

14.82

1.4

132.73

118.36

pmol/l

0.48

898

6837

Any reimbursement code in KELA

980

3699

1.34

14.77

1.5

1.4

148.37

57.84

pmol/l

4.27

961

3604

Hypothyroidism, strict autoimmune

1191

6151

1.29

14.65

1.4

124.98

117.16

pmol/l

0.26

1159

5999

L02BA Anti-estrogens

348

2229

1.59

14.53

1.4

1.5

109.16

159.46

pmol/l

1.58

341

2172

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

1316

7467

1.27

14.49

1.5

1.4

166.58

123.60

pmol/l

2.18

1281

7284

Dysphagia

236

1373

1.73

14.17

1.5

1.4

124.21

127.84

pmol/l

0.06

228

1343

Depression medications

480

1625

1.50

13.89

1.4

123.94

55.32

pmol/l

1.34

467

1582

Fentanyl

115

536

2.17

13.48

1.7

1.5

269.19

171.80

pmol/l

0.93

110

519

Fenamates

247

979

1.72

13.45

1.4

157.86

121.07

pmol/l

0.35

239

950

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

1335

7263

1.25

13.30

1.5

1.4

140.84

125.95

pmol/l

0.56

1292

7084

Agranulocytosis

168

906

1.89

13.19

1.7

1.5

265.14

178.81

pmol/l

0.76

163

888

First line medication for Crohn's disease

1555

6889

1.24

13.08

1.5

1.4

174.64

104.09

pmol/l

4.00

1509

6718

Other disorders of the genitourinary system

224

1320

1.73

13.08

1.6

1.5

94.54

202.07

pmol/l

4.90

218

1288

Benign neoplasm of other and ill-defined parts of digestive system

177

974

1.84

12.94

1.3

1.4

213.94

71.82

pmol/l

0.91

172

949

Other functional intestinal disorders

571

3915

1.40

12.88

1.5

1.4

170.13

143.65

pmol/l

0.47

555

3819

Cardiovascular diseases

1042

4416

1.29

12.74

1.5

1.4

115.69

80.97

pmol/l

1.26

1013

4306

Other soft tissue disorders, not elsewhere classified

1289

6396

1.25

12.33

1.4

129.13

123.37

pmol/l

0.11

1255

6235

Constipation

1123

6401

1.26

11.94

1.4

148.47

140.24

pmol/l

0.17

1090

6255

Diverticular disease of intestine

823

4179

1.31

11.89

1.5

1.4

146.71

153.45

pmol/l

0.17

799

4091

Major coronary heart disease event

359

3532

0.67

11.87

1.5

1.4

210.12

182.85

pmol/l

0.33

352

3441

Hypothyroidism, strict autoimmune, 3 medication purchases required

1338

7411

1.24

11.82

1.4

136.35

125.30

pmol/l

0.34

1301

7227

Headache

981

6453

1.28

11.75

1.5

1.4

86.28

118.04

pmol/l

3.39

951

6294

Other benign neoplasm of uterus: Other parts/unspecified

219

2.77

11.57

1.5

1.4

102.67

80.08

pmol/l

0.82

210

Dermatitis and eczema

1455

7839

1.22

11.36

1.4

104.65

129.76

pmol/l

1.60

1413

7639

Major coronary heart disease event excluding revascularizations

302

3130

0.66

11.03

1.5

1.4

211.09

190.80

pmol/l

0.21

296

3047

Other diseases of pleura

345

2067

1.49

10.90

1.5

1.4

358.06

184.31

pmol/l

3.62

331

2011

Melanocytic naevi

328

2207

1.50

10.87

1.5

1.4

83.66

58.39

pmol/l

1.37

319

2146

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

405

1924

1.45

10.85

1.5

1.4

195.85

82.13

pmol/l

2.40

394

1882

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

398

1899

1.45

10.63

1.5

1.4

194.49

82.42

pmol/l

2.25

384

1858

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

389

1857

1.45

10.52

1.5

1.4

194.71

83.05

pmol/l

2.18

377

1815

Sequelae with surgical and medical care as external cause

236

1491

1.60

10.49

1.6

1.4

147.29

168.64

pmol/l

0.30

230

1453

Dementia

137

1689

0.56

10.46

1.5

1.4

345.71

235.04

pmol/l

0.38

131

1634

Cardiovascular diseases (excluding rheumatic etc)

1072

4963

1.25

10.45

1.5

1.4

138.36

84.58

pmol/l

2.30

1048

4842

Tramadol

1050

5408

1.25

10.45

1.5

1.4

163.00

110.67

pmol/l

2.13

1016

5293

Codeine

1344

6062

1.22

10.38

1.5

1.4

119.27

103.35

pmol/l

0.53

1296

5926

Gastrointestinal diseases

948

3749

1.27

10.27

1.5

1.4

129.77

109.68

pmol/l

0.47

925

3650

Low back pain

1007

6218

1.25

10.25

1.5

1.4

107.09

125.28

pmol/l

0.71

973

6057

Inflammatory disease of uterus

293

1962

1.52

10.14

1.5

134.63

125.06

pmol/l

0.07

286

1914

Disorders of gallbladder, biliary tract and pancreas

1302

6906

1.22

10.07

1.5

1.4

124.59

135.14

pmol/l

0.45

1275

6743

Other special examinations and investigations of persons without complaint or reported diagnosis

881

3499

1.28

10.01

1.4

105.83

131.27

pmol/l

1.32

854

3431

Other diseases of blood and blood-forming organs, wide

264

1735

1.54

9.88

1.6

1.4

219.16

161.64

pmol/l

0.79

257

1694

In situ neoplasms

491

3620

1.37

9.83

1.4

119.51

157.53

pmol/l

1.38

479

3524

Sequelae of external causes of morbidity and mortality

284

1912

1.50

9.48

1.5

1.4

136.73

167.83

pmol/l

0.61

275

1857

Degenerative diseases of the nervous system

1266

0.50

9.47

1.4

319.72

256.86

pmol/l

0.24

1219

Haematosalpinx/Haematoma of broad ligament

10.66

9.22

2.7

1.4

53.18

102.58

pmol/l

0.46

Coxibs

304

1086

1.50

9.21

1.6

1.4

112.55

114.62

pmol/l

0.02

293

1050

Benzodiazepine use

1321

7831

1.20

9.20

1.4

175.39

118.79

pmol/l

1.94

1290

7631

Female infertility, uterine origin

6.80

9.17

1.7

1.5

64.40

88.38

pmol/l

0.36

Lower back pain or/and sciatica

1367

7925

1.20

9.16

1.5

1.4

117.22

127.37

pmol/l

0.27

1321

7731

Other specific joint derangements/joint disorders

1046

5710

1.23

9.13

1.4

110.54

114.19

pmol/l

0.09

1018

5561

Certain infectious and parasitic diseases

1474

6191

1.20

9.01

1.5

1.4

141.30

114.62

pmol/l

1.21

1423

6051

Cholecystectomy

975

7014

1.23

8.93

1.4

126.87

140.03

pmol/l

0.51

955

6846

Oedema, not elsewhere classified

364

2592

1.41

8.76

1.6

1.4

162.51

155.72

pmol/l

0.11

354

2525

Hard cardiovascular diseases

553

4635

0.76

8.67

1.5

1.4

225.56

158.10

pmol/l

1.02

542

4516

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

321

2262

1.44

8.59

1.4

68.26

122.37

pmol/l

5.13

308

2203

Neurotic, stress-related and somatoform disorders

1286

7653

1.20

8.56

1.5

1.4

122.47

123.26

pmol/l

0.02

1252

7462

Cholelithiasis, broad definition with cholecystitis

1188

6763

1.21

8.55

1.4

120.97

136.93

pmol/l

0.78

1169

6601

Cholelithiasis

1157

6726

1.21

8.54

1.4

120.92

137.40

pmol/l

0.79

1138

6566

Other disorders of skin and subcutaneous tissue

823

6058

1.25

8.52

1.5

1.4

107.94

149.89

pmol/l

4.29

800

5911

Anxiety disorders

1296

7699

1.20

8.50

1.5

1.4

122.13

123.99

pmol/l

0.05

1262

7506

Carcinoma in situ of other and unspecified digestive organs

3.75

8.50

1.3

1.5

170.46

67.26

pmol/l

0.78

Follow-up care involving plastic surgery

380

2.08

8.10

1.7

1.4

71.64

170.62

pmol/l

1.46

373

Pain in limb

1049

6267

1.22

8.09

1.4

128.26

125.02

pmol/l

0.06

1017

6111

Gastro-oesophageal reflux disease

842

6046

1.24

8.04

1.4

142.99

138.35

pmol/l

0.09

823

5903

Myocardial infarction

207

2247

0.66

8.03

1.6

1.5

258.12

204.71

pmol/l

0.43

202

2186

Organic, including symptomatic, mental disorders

208

2265

0.66

7.99

1.6

1.5

288.78

213.32

pmol/l

0.39

201

2205

Other and unspecified iron deficiency

383

2812

1.37

7.95

1.6

1.4

152.70

163.35

pmol/l

0.15

373

2724

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

1212

6613

1.20

7.90

1.4

147.86

127.58

pmol/l

0.53

1187

6455

Dorsalgia

1378

6310

1.19

7.87

1.5

1.4

103.30

124.11

pmol/l

0.76

1336

6146

Dementia, including avohilmo

164

1787

0.63

7.81

1.4

1.5

317.05

232.25

pmol/l

0.34

156

1733

Endocrine, nutritional and metabolic diseases

1170

4960

1.20

7.80

1.5

1.4

134.42

100.78

pmol/l

1.24

1139

4840

Gastrointestinal stromal tumor and sarcoma, excluding all cancers (controls excluding all cancers)

4.68

7.73

1.4

1.3

159.94

65.20

pmol/l

1.13

Bacterial infection, other or unspecified

504

3482

1.31

7.73

1.6

1.4

252.39

147.87

pmol/l

2.74

490

3397

Any dementia

121

1441

0.59

7.68

1.5

1.4

381.13

250.64

pmol/l

0.40

115

1389

Codeine or tramadol medication

1562

7413

1.17

7.63

1.4

126.90

123.49

pmol/l

0.09

1510

7239

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

401

1.99

7.56

1.5

1.4

222.01

82.31

pmol/l

0.88

388

Iron deficiency anaemia

485

3679

1.31

7.56

1.5

1.4

149.59

157.37

pmol/l

0.13

470

3574

Benign neoplasm of soft tissue of retroperitoneum and peritoneum

5.22

7.56

1.4

1.2

117.19

50.82

pmol/l

0.64

Stroke, including SAH

356

3576

0.73

7.52

1.5

1.4

243.65

174.24

pmol/l

0.69

349

3482

Malignant neoplasm of uterus, part unspecified, excluding all cancers (controls excluding all cancers)

6.32

7.50

1.4

183.39

87.34

pmol/l

0.46

Renal tubulo-interstitial diseases

1093

7012

1.20

7.46

1.5

1.4

211.41

118.06

pmol/l

5.95

1058

6834

Contraceptive management

606

3347

1.28

7.45

1.5

1.4

99.16

113.67

pmol/l

0.31

594

3275

General examination and investigation of persons without complaint and reported diagnosis

813

3497

1.24

7.42

1.5

1.4

145.33

131.20

pmol/l

0.25

788

3429

Injuries to the head

1062

8261

0.83

7.41

1.4

125.10

125.23

pmol/l

0.00

1020

8062

Emergency coronary revascularization (for ACS)

169

1882

0.64

7.41

1.5

206.47

231.94

pmol/l

0.24

161

1829

Acetic acid derivatives and related substances

296

1077

1.44

7.40

1.5

1.4

187.32

115.20

pmol/l

0.81

289

1042

Recurrent or chronic depression

636

3640

1.27

7.33

1.4

98.00

121.60

pmol/l

0.98

622

3558

Benign neoplasm: Sigmoid colon

125

740

1.70

7.31

1.3

1.4

156.18

77.00

pmol/l

1.17

119

720

Septicaemia

355

2510

1.37

7.29

1.6

1.4

215.65

164.54

pmol/l

1.12

346

2439

Other diseases of intestine

123

729

1.70

7.20

1.4

157.50

183.36

pmol/l

0.32

116

713

Coronary atherosclerosis

413

3521

0.75

7.20

1.4

154.50

182.74

pmol/l

0.92

401

3437

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

307

2.10

7.17

1.3

1.4

239.96

80.78

pmol/l

0.79

296

Other diseases of hard tissues of teeth

852

5213

1.22

7.14

1.4

92.37

128.65

pmol/l

4.03

824

5097

Other septicaemia

313

2224

1.39

7.10

1.6

1.4

212.38

165.88

pmol/l

1.04

305

2164

Abnormalities of breathing

1254

6318

1.18

7.10

1.4

149.87

118.87

pmol/l

0.98

1217

6170

Explicit Sepsis

408

2952

1.33

7.06

1.5

1.4

193.90

161.55

pmol/l

0.68

397

2868

Angina pectoris

343

3131

0.74

7.03

1.4

152.08

187.73

pmol/l

0.98

335

3054

Benign neoplasm: Caecum

406

1.94

7.00

1.5

1.4

211.02

81.25

pmol/l

1.33

393

Any dementia, excluding more controls

121

1380

0.61

6.91

1.5

1.4

381.13

238.40

pmol/l

0.45

115

1340

Coronary revascularization (ANGIO or CABG)

165

1765

0.65

6.91

1.4

1.5

207.15

225.22

pmol/l

0.16

157

1712

Bacterial pneumoniae

212

2723

0.69

6.84

1.6

1.4

137.89

163.93

pmol/l

0.51

205

2645

Diseases of arteries, arterioles and capillaries

366

3634

0.75

6.80

1.4

170.26

176.59

pmol/l

0.10

353

3541

Anxiety disorders, excluding more controls

1188

6688

1.18

6.77

1.5

1.4

128.86

125.03

pmol/l

0.09

1157

6529

Hypertension, essential

1063

5095

1.19

6.71

1.5

1.4

154.11

113.76

pmol/l

1.47

1032

4992

Cerebrovascular diseases

488

4467

0.78

6.65

1.5

1.4

214.57

162.00

pmol/l

0.70

478

4354

Triptan medication for migraine, single purchase ok

1224

7078

1.18

6.54

1.4

80.54

124.88

pmol/l

6.86

1192

6899

Migraine, single triptan purchase ok & required. ICD-code if available is included

1224

7078

1.18

6.54

1.4

80.54

124.88

pmol/l

6.86

1192

6899

Dyspnoea

1097

7122

1.18

6.52

1.5

1.4

181.42

126.86

pmol/l

1.87

1065

6950

Depression or dysthymia

910

4229

1.21

6.49

1.4

124.68

137.09

pmol/l

0.30

882

4132

Chronic diseases of tonsils and adenoids

1153

6202

1.18

6.49

1.4

84.91

129.11

pmol/l

4.90

1120

6054

Stroke, excluding SAH

321

3201

0.74

6.37

1.5

1.4

258.40

183.82

pmol/l

0.66

314

3115

Persons encountering health services in circumstances related to reproduction

714

3945

1.23

6.36

1.5

1.4

126.11

127.50

pmol/l

0.02

698

3845

Atrophic disorders of skin

227

1595

1.44

6.31

1.5

1.4

90.92

179.98

pmol/l

5.25

220

1558

Nutritional anaemias

543

4208

1.26

6.27

1.5

1.4

145.97

154.57

pmol/l

0.16

528

4095

Malignant neoplasm of breast

932

5658

1.20

6.13

1.4

146.68

153.99

pmol/l

0.19

909

5527

Disorders of thyroid, IBD co-morbidities

293

1562

1.38

6.13

1.3

1.4

146.59

124.24

pmol/l

0.22

285

1529

Other noninfective gastroenteritis and colitis

278

2029

1.38

6.10

1.4

109.81

157.98

pmol/l

1.39

271

1971

Other degenerative diseases of the nervous system

161

1824

0.67

6.07

1.4

187.85

173.82

pmol/l

0.09

155

1777

Ischaemic Stroke, excluding all haemorrhages

288

2940

0.74

6.00

1.5

1.4

226.75

191.86

pmol/l

0.39

281

2859

Bacterial pneumonia, not elsewhere classified

202

2550

0.70

6.00

1.6

1.4

141.88

168.55

pmol/l

0.50

195

2474

Propionic acid derivatives

300

1098

1.38

5.97

1.4

187.19

113.90

pmol/l

0.68

290

1061

Anti-inflammatory and antirheumatic products, non-steroids

300

1098

1.38

5.97

1.5

1.4

178.35

113.90

pmol/l

0.58

291

1061

All pneumoniae

970

7890

0.85

5.96

1.5

1.4

147.89

123.93

pmol/l

0.83

944

7694

Bacterial pneumonia (organism specified)

226

2876

0.71

5.95

1.6

1.4

147.08

161.05

pmol/l

0.22

219

2793

Diseases of oesophagus, stomach and duodenum

1374

7240

1.16

5.93

1.4

150.93

125.49

pmol/l

0.77

1340

7061

Selective serotonin reuptake inhibitors

1304

5921

1.16

5.93

1.5

1.4

118.73

128.69

pmol/l

0.33

1270

5778

Mesothelioma, excluding all cancers (controls excluding all cancers)

5.61

5.83

1.4

1.5

100.91

59.45

pmol/l

1.70

Unspecified urinary incontinence

135

869

1.58

5.82

1.4

1.5

78.98

202.18

pmol/l

5.42

126

845

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

928

7688

0.85

5.76

1.5

1.4

150.60

125.80

pmol/l

0.83

906

7496

Diseases of pulp and periapical tissues

387

2993

1.30

5.76

1.4

1.5

188.92

131.61

pmol/l

1.17

378

2923

Hypertensive diseases (excluding secondary)

804

3889

1.21

5.74

1.5

1.4

162.69

95.78

pmol/l

2.30

786

3808

Pneumonias (Asthma/COPD co-morbidities)

963

7840

0.85

5.73

1.5

1.4

148.13

124.27

pmol/l

0.82

937

7644

Endometriosis in cutaneous scar

6.32

5.72

1.9

1.3

40.30

84.88

pmol/l

—

Symptoms and signs involving the circulatory and respiratory systems

1446

6318

1.15

5.67

1.4

107.70

118.87

pmol/l

0.55

1399

6170

Other reaction to severe stress, and adjustment disorders

552

4466

1.24

5.66

1.5

1.4

137.45

104.28

pmol/l

0.80

538

4348

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

295

1.98

5.63

1.3

1.4

255.36

81.11

pmol/l

0.78

284

Atherosclerosis, excluding cerebral and coronary sclerosis

135

1637

0.66

5.54

1.5

1.4

244.46

233.21

pmol/l

0.07

128

1584

Acute tubulo-interstitial nephritis

762

5649

1.20

5.52

1.5

1.4

191.50

124.39

pmol/l

2.41

738

5506

Peripheral artery disease

152

1809

0.67

5.48

1.5

1.4

234.28

223.69

pmol/l

0.08

146

1751

Benign neoplasm of colon, rectum, anus and anal canal

597

4403

1.23

5.47

1.4

153.15

170.72

pmol/l

0.44

583

4289

Special screening examination for infectious and parasitic diseases

330

1873

1.32

5.44

1.4

80.08

92.60

pmol/l

0.26

313

1837

Non-invasive ventilation

277

1936

1.35

5.43

1.5

1.4

110.16

114.52

pmol/l

0.08

250

1887

Liposarcoma, excluding all cancers (controls excluding all cancers)

4.47

5.34

1.2

75.62

61.40

pmol/l

0.53

Hepatomegaly and splenomegaly, not elsewhere classified

3.97

5.32

1.5

1.3

100.27

63.85

pmol/l

0.71

Marginal zone B-cell lymphoma, excluding all cancers (controls excluding all cancers)

3.30

5.22

1.4

1.3

118.42

62.39

pmol/l

1.44

Other dorsopathies, not elsewhere classified

1368

6314

1.15

5.18

1.5

1.4

115.65

124.06

pmol/l

0.22

1332

6150

Neurological diseases, wide definition

443

1752

1.27

5.16

1.5

1.4

114.28

115.20

pmol/l

0.01

429

1712

Hypothyroidism, drug reimbursement

227

1174

1.39

5.14

1.4

79.04

60.83

pmol/l

0.65

221

1153

Chronic periapical parodontitis

212

1528

1.40

5.13

1.5

238.71

147.11

pmol/l

1.07

206

1495

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

959

6715

1.17

5.11

1.4

85.74

116.62

pmol/l

2.49

935

6555

Persons encountering health services for examination and investigation

829

3499

1.19

5.11

1.5

1.4

141.35

131.27

pmol/l

0.17

806

3431

Mood [affective] disorders

1358

7838

1.14

5.10

1.4

106.70

128.93

pmol/l

1.39

1318

7643

L02BG Aromatase inhibitors

485

3922

1.25

5.10

1.6

1.4

156.23

176.54

pmol/l

0.52

473

3827

Diseases of liver

330

2545

1.30

5.08

1.4

197.40

160.94

pmol/l

0.55

320

2481

Other antidepressants

1300

5921

1.15

5.08

1.4

117.78

128.69

pmol/l

0.28

1256

5778

Mood disorders

1360

7843

1.14

5.07

1.4

106.63

129.05

pmol/l

1.41

1320

7648

Acute pharyngitis

151

1020

1.48

5.02

1.4

1.5

60.40

113.55

pmol/l

1.97

141

994

Depression

1284

7746

1.14

4.98

1.4

103.12

127.80

pmol/l

1.58

1247

7556

Malignant neoplasm of breast, HER-positive

586

4781

1.22

4.93

1.4

119.22

166.88

pmol/l

2.66

573

4667

Inguinal hernia

223

2046

0.73

4.92

1.5

1.4

153.80

154.57

pmol/l

0.01

217

1983

Other diseases of anus and rectum

302

2312

1.31

4.89

1.4

183.61

163.20

pmol/l

0.17

289

2253

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

718

3818

1.20

4.88

1.4

126.01

95.80

pmol/l

0.89

704

3738

Benign neoplasm: Colon

477

3783

1.24

4.88

1.4

150.88

181.84

pmol/l

0.87

463

3686

Malignant neoplasm of vulva, excluding all cancers (controls excluding all cancers)

2.83

4.85

1.3

1.4

104.26

63.55

pmol/l

1.25

DVT of lower extremities

180

1281

1.41

4.73

1.4

243.12

189.14

pmol/l

0.32

173

1242

Sulfonylureas

128

1512

0.67

4.71

1.4

1.5

271.35

210.03

pmol/l

0.77

123

1467

Ischemic heart diseases

597

4497

0.83

4.70

1.4

176.35

166.62

pmol/l

0.15

580

4389

Malignant neoplasm of breast, HER2-negative

884

5579

1.17

4.68

1.4

144.43

153.59

pmol/l

0.25

862

5450

Ischaemic heart disease, wide definition

579

4363

0.83

4.62

1.4

196.17

166.61

pmol/l

0.38

562

4258

Phlebitis and thrombophlebitis (not including DVT)

247

1862

1.33

4.55

1.4

206.52

160.43

pmol/l

0.39

236

1809

Migraine

825

6018

1.17

4.52

1.4

69.45

119.09

pmol/l

9.69

797

5873

Other anaemias

348

2651

1.27

4.48

1.6

1.4

184.32

187.15

pmol/l

0.04

334

2573

Hypertension

1061

5235

1.15

4.36

1.5

1.4

160.95

112.04

pmol/l

1.94

1034

5126

Other and unspecified anaemias

341

2610

1.27

4.33

1.6

1.4

181.21

188.01

pmol/l

0.09

328

2532

Hypertensive diseases

1061

5240

1.15

4.32

1.5

1.4

160.95

111.97

pmol/l

1.94

1034

5131

Single spontaneous delivery

592

3759

0.83

4.28

1.4

173.72

147.87

pmol/l

0.36

572

3653

Myalgia

333

2644

1.27

4.19

1.5

1.4

96.73

123.38

pmol/l

0.67

326

2574

Temporomandibular joint disorders

229

1733

1.33

4.16

1.5

1.4

77.43

131.92

pmol/l

3.87

221

1693

Acute renal failure

133

919

1.45

4.15

1.9

1.4

355.49

210.18

pmol/l

1.49

124

894

177

1289

1.38

4.15

1.4

160.48

135.80

pmol/l

0.28

171

1257

Benign lipomatous neoplasm

320

2531

1.27

4.14

1.4

179.02

162.70

pmol/l

0.14

314

2462

Oxicams

223

944

1.35

4.13

1.4

194.58

125.02

pmol/l

0.67

217

915

Acute upper respiratory infections

1372

7659

1.12

4.11

1.5

1.4

110.02

131.04

pmol/l

1.21

1333

7472

Abnormal results of function studies

610

1.56

4.02

1.5

237.48

161.18

pmol/l

0.29

597

Influenza and pneumonia

1084

8076

0.88

4.01

1.5

1.4

141.57

123.01

pmol/l

0.65

1055

7871

Other disorders of teeth and supporting structures

222

1683

1.33

3.99

1.5

128.92

152.53

pmol/l

0.58

216

1643

Malignant neoplasm of vagina, excluding all cancers (controls excluding all cancers)

4.50

3.98

1.2

116.40

70.77

pmol/l

—

Asthma (mode)

1057

5099

1.14

3.93

1.5

1.4

147.06

117.02

pmol/l

0.69

1030

4994

Dorsopathies

1386

6316

1.12

3.90

1.5

1.4

103.49

124.03

pmol/l

1.15

1348

6152

Disorders of eyelid, lacrimal system and orbit

1039

7184

1.14

3.86

1.4

98.91

141.33

pmol/l

4.81

1014

7010

Noninfective enteritis and colitis

512

4283

1.20

3.85

1.4

92.30

132.70

pmol/l

2.55

498

4166

Pneumonia, organism unspecified

846

7020

0.87

3.85

1.5

1.4

147.51

130.24

pmol/l

0.47

825

6850

Use of rivastigmine

619

0.50

3.84

1.3

1.5

145.81

280.43

pmol/l

2.48

590

Other embolism and thrombosis

131

920

1.43

3.81

1.4

157.32

187.41

pmol/l

0.35

123

898

Benign neoplasm of bone and articular cartilage

539

1.57

3.80

1.5

1.3

72.53

61.85

pmol/l

0.48

526

All anxiety disorders

855

6005

1.15

3.75

1.5

1.4

83.81

104.90

pmol/l

1.56

835

5855

Follicular adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

2.87

3.74

1.6

1.3

76.12

57.66

pmol/l

0.46

Other/unspecified dorsalgia

472

3917

1.20

3.73

1.5

1.4

102.39

143.05

pmol/l

2.72

460

3811

956

6808

0.88

3.72

1.5

1.4

148.00

127.10

pmol/l

0.66

933

6647

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

956

6808

0.88

3.72

1.5

1.4

148.00

127.10

pmol/l

0.66

933

6647

Malignant neoplasm of uterus, part unspecified

12.45

3.70

1.8

1.2

98.83

75.50

pmol/l

—

Abnormal findings on diagnostic imaging of lung

381

3033

1.23

3.68

1.4

197.41

176.19

pmol/l

0.19

373

2962

Car occupant injured in other and unspecified transport accidents

216

1654

1.31

3.66

1.5

95.76

129.11

pmol/l

0.74

205

1608

Diseases of the skin and subcutaneous tissue

1358

6100

1.12

3.64

1.5

1.4

103.89

129.79

pmol/l

2.05

1317

5939

Other diseases of the digestive system

223

1719

1.30

3.58

1.7

1.4

148.36

199.20

pmol/l

1.00

216

1662

Follicular lymphoma

157

2.06

3.57

1.5

1.4

95.44

63.44

pmol/l

1.68

151

External causes of morbidity and mortality

1007

4446

1.14

3.56

1.4

114.09

130.94

pmol/l

0.49

986

4346

Polyuria

169

1254

1.35

3.55

1.3

1.4

91.87

166.53

pmol/l

2.01

158

1220

Oter anti-inflammatory and antirheumatic agents, non-steroids

198

824

1.34

3.53

1.5

1.4

129.43

135.02

pmol/l

0.08

192

799

Other neurological diseases

555

5240

0.85

3.53

1.5

1.4

126.62

156.07

pmol/l

1.18

535

5109

Aplastic and other anaemias

370

2877

1.22

3.48

1.7

1.4

201.25

186.07

pmol/l

0.22

356

2793

Tonsillectomy and adenotomy

815

4962

1.15

3.46

1.4

63.38

96.06

pmol/l

4.91

788

4841

Delivery

610

3764

0.85

3.46

1.4

171.14

147.77

pmol/l

0.33

592

3658

Transient ischemic attack

324

3297

0.81

3.39

1.5

1.4

165.46

183.93

pmol/l

0.32

312

3213

Inflammatory disease of cervix uteri

109

762

1.45

3.35

1.4

1.5

212.09

192.79

pmol/l

0.06

104

743

Varicose veins

770

5085

1.15

3.33

1.4

199.44

146.33

pmol/l

1.09

755

4965

Injury, poisoning and certain other consequences of external causes

845

3709

1.14

3.32

1.5

1.4

123.48

129.85

pmol/l

0.12

827

3625

Asthma, including avohilmo

1474

7759

1.11

3.31

1.4

136.84

121.92

pmol/l

0.40

1438

7555

Insulin medication

395

4052

0.83

3.27

1.4

179.14

134.60

pmol/l

1.24

380

3947

Diagnoses used for exclusion with ILD

209

1621

1.29

3.25

1.4

185.43

169.55

pmol/l

0.11

203

1584

Carcinoma in situ of rectum

3.67

3.23

1.4

1.3

109.50

58.14

pmol/l

—

Anxiety (asthma-related co-morbidities)

847

5891

1.14

3.21

1.5

1.4

84.12

116.55

pmol/l

2.68

829

5748

Dental pulpitis 4, only avohilmo

1426

6740

1.11

3.21

1.4

126.74

126.50

pmol/l

0.01

1382

6566

Obesity, other/unspecified

452

3818

1.19

3.19

1.5

1.4

110.57

112.86

pmol/l

0.04

433

3723

Benign neoplasm: Pelvic bones, sacrum and coccyx

4.73

3.17

1.6

1.5

54.89

67.33

pmol/l

—

Other heart diseases

646

3693

1.16

3.17

1.4

149.03

97.30

pmol/l

1.46

625

3614

Atrial fibrillation and flutter

346

1852

1.22

3.15

1.4

232.23

130.62

pmol/l

1.24

331

1817

Diseases of the digestive system

392

3266

1.20

3.12

1.6

1.4

134.62

163.40

pmol/l

0.83

381

3170

Acquired atrophy of ovary and fallopian tube

5.32

3.12

2.0

1.3

53.38

93.31

pmol/l

—

Glucosamine medication

531

3628

1.17

3.10

1.4

1.5

156.07

196.75

pmol/l

1.33

516

3538

Melanocytic naevi of trunk

105

739

1.43

3.10

1.5

1.4

111.70

56.28

pmol/l

0.94

105

719

Infections of the skin and subcutaneous tissue

567

4869

1.16

3.07

1.5

1.4

152.38

123.09

pmol/l

0.45

553

4738

Factors influencing health status and contact with health services

290

1168

1.25

3.07

1.4

209.96

123.79

pmol/l

0.83

285

1151

Mood disorders, excluding more controls

1227

6734

1.11

3.07

1.4

110.21

125.75

pmol/l

0.75

1194

6573

Other viral diseases

321

2629

1.22

3.07

1.4

82.24

109.61

pmol/l

1.26

310

2555

Heart failure, not strict

734

4432

1.14

3.06

1.6

1.4

234.32

150.85

pmol/l

2.22

713

4328

Mucinous and mucinous cystic tumor of rectum, excluding all cancers (controls excluding all cancers)

6.06

3.05

1.6

1.4

85.77

62.58

pmol/l

—

Other diseases of upper respiratory tract

1393

6589

1.10

3.04

1.5

1.4

109.28

136.29

pmol/l

1.98

1350

6426

Dental pulpitis 1

1403

6614

1.10

3.04

1.4

134.55

123.17

pmol/l

0.37

1357

6444

Dental pulpitis 4

1402

6612

1.10

3.00

1.4

134.71

123.18

pmol/l

0.38

1356

6442

Disorders of other endocrine glands

521

4404

1.17

2.99

1.5

1.4

129.83

142.31

pmol/l

0.21

508

4279

Intracranial trauma

580

5001

0.86

2.99

1.4

112.05

125.46

pmol/l

0.47

558

4882

Sequelae of cerebrovascular disease

149

1731

0.75

2.98

1.5

1.4

244.57

206.70

pmol/l

0.27

143

1677

Dental caries 2 and operation codes, only avohilmo

879

4843

1.13

2.95

1.3

1.4

78.43

115.99

pmol/l

4.66

853

4710

Irritable bowel syndrome

377

3159

1.20

2.95

1.4

84.48

132.26

pmol/l

3.18

361

3080

Dental pulpitis 1, only avohilmo

1423

6763

1.10

2.92

1.4

124.30

126.83

pmol/l

0.07

1380

6588

Noninfectious colitis NAS

147

1107

1.34

2.90

1.5

98.14

171.18

pmol/l

2.15

142

1080

Other diseases of liver

185

1438

1.29

2.90

1.3

1.4

219.27

163.10

pmol/l

0.56

177

1405

Other anxiety disorders

625

4837

1.15

2.88

1.5

1.4

82.00

102.01

pmol/l

1.11

611

4712

Diseases of pulp and periapical tissues, including avohilmo

1398

6609

1.10

2.88

1.4

134.79

123.20

pmol/l

0.38

1352

6439

Kela-code for severe mental illness

278

3394

0.82

2.87

1.4

1.5

92.50

125.98

pmol/l

2.20

267

3306

Primary ovarian failure

247

1.74

2.82

1.5

1.4

69.84

137.71

pmol/l

0.77

241

Other disorders of skin and subcutaneous tissue, not elsewhere classified

140

1053

1.34

2.79

1.5

130.72

180.67

pmol/l

0.91

135

1031

STROKE

519

4167

0.86

2.79

1.5

1.4

183.96

149.98

pmol/l

0.45

505

4064

Atrial fibrillation and flutter with reimbursement

269

1399

1.24

2.76

1.3

1.4

223.16

149.35

pmol/l

0.75

260

1372

Coronary angioplasty

144

1455

0.76

2.76

1.4

180.00

227.95

pmol/l

0.53

136

1409

Benign neoplasm: Appendix

2.66

2.73

1.1

1.4

155.64

59.06

pmol/l

1.16

Other bacterial diseases

1027

6396

1.11

2.73

1.5

1.4

217.16

126.62

pmol/l

4.21

996

6250

Other disorders of fluid, electrolyte and acid-base balance

265

2086

1.23

2.72

1.7

1.4

302.75

176.24

pmol/l

1.16

251

2038

Benign neoplasm of mouth and pharynx

575

1.45

2.71

1.6

1.4

100.64

70.28

pmol/l

0.70

558

Chronic lymphocytic leukaemia, helper endpoint

2.52

2.71

1.4

1.5

173.87

68.03

pmol/l

0.67

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

2.52

2.71

1.4

1.5

173.87

68.03

pmol/l

0.67

Disorders of lacrimal system

537

4669

1.15

2.69

1.4

103.86

161.46

pmol/l

3.50

522

4553

Melanocytic naevi of lower limb, including hip

288

1.65

2.68

1.4

81.21

52.65

pmol/l

0.59

281

Functional dyspepsia

332

2778

1.20

2.68

1.6

1.4

107.94

143.77

pmol/l

1.40

324

2695

Asthma

1048

5067

1.11

2.66

1.5

1.4

138.12

116.61

pmol/l

0.49

1020

4962

Metabolic disorders

1103

6200

1.11

2.66

1.5

1.4

195.01

128.17

pmol/l

2.48

1060

6073

Abnormal findings in secretions and smears from cervix uteri vagina vulva

939

6638

1.12

2.66

1.4

83.94

115.33

pmol/l

2.53

915

6482

Asthma, unspecified (mode), excluding more controls

672

4652

1.14

2.65

1.5

1.4

203.58

116.88

pmol/l

1.80

659

4560

Other disorders of lacrimal gland

438

3757

1.17

2.64

1.3

1.4

105.96

159.45

pmol/l

2.33

425

3661

HSIL lesion of the cervix uteri, vagina or vulva

367

3108

1.19

2.62

1.4

1.5

86.69

100.85

pmol/l

0.40

362

3034

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

2.48

2.62

1.5

1.4

143.80

69.88

pmol/l

0.82

Adenocarcinoma of small intestine, excluding all cancers (controls excluding all cancers)

7.49

2.58

1.0

1.6

69.40

76.49

pmol/l

—

Asthma, unspecified (mode)

679

4759

1.13

2.57

1.5

1.4

208.96

120.98

pmol/l

1.84

665

4663

Benign neoplasm: Colon, unspecified

184

1453

1.27

2.57

1.4

1.5

130.11

220.68

pmol/l

2.81

178

1411

Ulcerative enterocolitis

223

1.73

2.56

1.5

1.4

64.34

179.05

pmol/l

0.93

218

Visual impairment including blindness (binocular or monocular)

395

1.53

2.54

1.5

1.4

259.45

219.13

pmol/l

0.15

386

Chronic laryngitis and laryngotracheitis

155

1201

1.30

2.54

1.5

1.4

93.55

176.66

pmol/l

2.93

148

1176

Injuries to the wrist and hand

1013

8102

0.90

2.54

1.4

109.68

124.08

pmol/l

0.43

982

7896

Abnormalities of heart beat

420

3571

1.17

2.53

1.6

1.4

102.57

142.75

pmol/l

1.76

412

3487

Peripheral artery operations in Hilmo

436

0.53

2.53

1.6

1.5

338.30

267.27

pmol/l

0.12

426

Unspecified mental disorder

337

3986

0.84

2.52

1.4

89.93

120.73

pmol/l

2.26

326

3883

Type 1 diabetes, strict (exclude DM2)

722

0.63

2.52

1.4

72.07

92.96

pmol/l

0.47

704

Renal failure

265

1995

1.22

2.50

1.8

1.4

338.14

205.08

pmol/l

2.97

247

1943

Infections with a predominantly sexual mode of transmission

439

3788

1.16

2.46

1.4

1.5

76.44

103.57

pmol/l

2.23

424

3693

Other benign neoplasm of uterus: Other parts/unspecified

392

1.53

2.44

1.5

1.4

102.67

304.61

pmol/l

3.58

378

Benign neoplasm: Other and unspecified parts of small intestine

2.32

2.43

1.1

1.4

113.94

62.87

pmol/l

0.69

Obstructed labour due to malposition and malpresentation of fetus

329

3656

0.84

2.43

1.4

96.82

89.76

pmol/l

0.06

321

3576

Attention to artificial openings

145

1.88

2.42

1.9

1.4

168.81

291.45

pmol/l

0.49

145

Asthma (diagnoses ohter than nonallergic)

1055

8208

1.10

2.42

1.5

1.4

169.38

120.58

pmol/l

1.38

1032

7989

Antihypertensive medication - note that there are other indications

914

4504

1.11

2.41

1.5

1.4

122.11

89.78

pmol/l

0.93

893

4385

Type 1 diabetes, definitions combined

726

0.64

2.41

1.4

71.26

93.28

pmol/l

0.51

708

Excluding asthma or asthma-COPD overlap

1122

5111

1.10

2.41

1.5

1.4

148.34

116.40

pmol/l

1.16

1084

5002

198

1407

1.25

2.41

1.4

1.5

194.75

255.58

pmol/l

1.01

186

1363

Umbilical hernia

196

1575

1.25

2.39

1.4

159.83

136.17

pmol/l

0.25

190

1533

Asthma, excluding more controls

1026

4958

1.10

2.38

1.5

1.4

137.16

112.70

pmol/l

0.58

998

4857

Malaise and fatigue

510

3713

1.15

2.37

1.4

190.18

138.01

pmol/l

0.82

489

3619

Coagulation defects, purpura and other haemorrhagic conditions

191

1533

1.25

2.37

1.4

127.20

150.36

pmol/l

0.50

185

1490

Disorders of skin appendages

559

4923

1.14

2.35

1.4

103.59

121.94

pmol/l

0.61

546

4796

Other predominantly sexually transmitted diseases, not elsewhere classified

242

1995

1.22

2.35

1.3

1.5

70.73

110.91

pmol/l

2.19

234

1947

L01XE Protein kinase inhibitors

339

1.55

2.33

1.4

1.5

117.48

232.98

pmol/l

1.44

334

Gastroduodenal ulcer

177

1407

1.26

2.32

1.5

1.4

198.98

203.17

pmol/l

0.04

169

1361

Malignant immunoproliferative diseases

3.28

2.32

1.6

1.3

86.28

79.59

pmol/l

—

Carcinoma in situ of colon

2.90

2.32

1.1

1.4

293.30

73.73

pmol/l

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

603

1.40

2.30

1.6

164.84

221.59

pmol/l

0.64

593

Malignant neoplasm of bone and articular cartilage of other and unspecified sites, excluding all cancers (controls excluding all cancers)

2.60

2.29

2.1

1.3

142.83

60.03

pmol/l

0.64

Delivery, wide proxy

511

3100

0.87

2.26

1.4

169.81

152.71

pmol/l

0.20

492

3009

HSIL lesion of the cervix uteri

335

2860

1.18

2.24

1.4

1.5

84.11

99.19

pmol/l

0.40

330

2793

Benign neoplasm: Choroid

279

1.59

2.23

1.8

1.4

84.67

81.85

pmol/l

0.04

269

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

156

1.79

2.23

1.4

139.57

71.36

pmol/l

1.16

151

Other benign neoplasms of skin

392

3385

1.16

2.23

1.5

1.4

128.97

157.33

pmol/l

0.74

385

3289

Fibromyalgia

154

1220

1.27

2.20

1.4

105.02

125.21

pmol/l

0.41

146

1193

Malignant neoplasm of rectosigmoid junction, excluding all cancers (controls excluding all cancers)

2.14

2.19

1.2

1.5

357.44

62.84

pmol/l

0.57

Radiculopathy

157

1245

1.27

2.19

1.5

1.4

134.67

198.24

pmol/l

1.59

150

1208

Injuries to the shoulder and upper arm

694

6483

0.90

2.18

1.5

1.4

141.06

140.47

pmol/l

0.01

679

6312

Other pulmonary diagnosis

1116

5111

1.10

2.18

1.5

1.4

151.87

116.40

pmol/l

1.32

1078

5002

Exposure to other specified factors

671

7017

0.89

2.17

1.5

1.4

110.49

124.80

pmol/l

0.57

649

6833

Asthma (only as main-diagnosis)

925

5067

1.10

2.16

1.5

1.4

112.54

116.61

pmol/l

0.10

903

4962

Purpura and other haemorrhagic conditions

122

940

1.30

2.14

1.5

139.54

165.04

pmol/l

0.37

117

918

Premature rupture of membranes

431

2760

1.15

2.13

1.4

59.28

86.79

pmol/l

2.02

422

2694

COPD differential diagnosis

1112

5099

1.09

2.12

1.5

1.4

142.83

117.02

pmol/l

0.88

1075

4994

Migraine without aura

327

2800

1.17

2.11

1.4

60.79

107.88

pmol/l

4.84

317

2736

Autoimmune diseases related-to ILD

1004

8079

1.09

2.11

1.4

101.83

130.06

pmol/l

2.47

978

7874

GI-bleeding

206

1690

1.22

2.11

1.7

1.4

158.48

198.22

pmol/l

0.65

198

1635

Maternal care for other conditions predominantly related to pregnancy

299

3458

0.85

2.10

1.3

1.4

71.72

89.32

pmol/l

1.06

290

3380

Visual disturbances and blindness

545

4834

1.13

2.10

1.4

135.29

142.08

pmol/l

0.14

526

4712

Malignant neoplasm of heart, mediastinum and pleura, excluding all cancers (controls excluding all cancers)

2.59

2.10

1.2

1.3

92.55

61.10

pmol/l

0.90

Fibrosis and cirrhosis of liver

463

1.44

2.10

1.5

117.86

239.30

pmol/l

1.85

456

1493

7315

1.08

2.09

1.5

1.4

119.98

126.67

pmol/l

0.23

1447

7140

ILD differential diagnosis

1111

5099

1.09

2.08

1.5

1.4

142.90

117.02

pmol/l

0.89

1074

4994

Noise effects on inner ear

0.00

2.07

0.0

1.4

—

89.94

—

Symptoms and signs involving the urinary system

757

5283

1.11

2.06

1.4

117.70

153.69

pmol/l

1.38

725

5157

Malignant neoplasm of thymus, excluding all cancers (controls excluding all cancers)

4.13

2.06

1.0

1.1

189.33

53.93

pmol/l

—

Benign neoplasm of other and ill-defined parts of digestive system

177

1436

1.24

2.05

1.3

1.5

213.94

175.86

pmol/l

0.16

172

1402

Abnormal findings in peritoneal fluid saliva

2.94

2.04

6.6

1.6

223.11

84.28

pmol/l

—

Acute inflammation of orbit

2.70

2.03

1.4

1.3

60.50

63.19

pmol/l

—

Beningn neoplasm: Meninges, unspecified

2.03

2.02

1.8

1.4

93.73

62.49

pmol/l

0.58

Other viral diseases, not elsewhere classified

186

1515

1.23

2.02

1.5

87.13

128.53

pmol/l

1.27

180

1477

L01XX Other antineoplastic agents

311

1.52

2.01

1.6

1.5

381.45

298.18

pmol/l

0.30

306

Other inflammatory liver diseases

476

1.42

2.01

1.4

1.5

101.30

189.05

pmol/l

1.45

466

Anankastic personality disorder

363

0.54

2.00

1.7

1.4

45.75

116.88

pmol/l

1.46

354

Sub-endpoint used in defining T1D endpoints

164

1990

0.81

1.99

1.4

1.5

189.04

134.95

pmol/l

0.82

157

1933

Hirsutism in women

242

1.60

1.97

1.4

49.03

112.64

pmol/l

0.82

236

Episodal and paroxysmal disorders

1455

6929

1.08

1.96

1.4

109.08

128.86

pmol/l

1.06

1410

6755

Certolizumab pegol

185

0.43

1.96

1.8

1.4

57.50

158.69

pmol/l

—

179

Hypertrichosis

266

1.57

1.96

1.4

56.85

128.92

pmol/l

0.93

260

Type 1 diabetes, strict definition

595

0.65

1.96

1.4

67.77

86.30

pmol/l

0.33

579

Benign neoplasm: Other and unspecified parts of mouth

164

1.72

1.95

1.4

60.75

59.64

pmol/l

0.05

159

Implicit viral Sepsis

150

1202

1.25

1.95

1.5

1.4

157.73

170.85

pmol/l

0.16

140

1165

Nephropathy related operations

546

1.38

1.95

1.7

1.5

510.80

196.73

pmol/l

3.53

536

Other intervertebral disc disorders

1025

5760

1.09

1.94

1.4

138.28

131.71

pmol/l

0.17

995

5622

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

429

1.43

1.93

1.3

1.5

237.99

268.24

pmol/l

0.09

419

Abnormal findings on examination of blood, without diagnosis

281

2240

1.18

1.92

1.6

1.4

213.81

156.02

pmol/l

0.48

272

2174

Type 1 diabetes

152

1878

0.81

1.92

1.4

177.73

117.68

pmol/l

0.92

147

1826

Exposure to unspecified factor

988

8336

0.92

1.91

1.4

111.31

127.29

pmol/l

0.68

962

8119

Ulcerative colitis

241

2030

1.19

1.91

1.4

73.21

139.58

pmol/l

5.40

236

1975

Asthma (only as main-diagnosis), excluding more controls

911

4958

1.10

1.91

1.5

1.4

109.03

112.70

pmol/l

0.09

890

4857

Viral Sepsis

150

1205

1.25

1.91

1.5

1.4

157.73

175.41

pmol/l

0.22

140

1168

Alzheimer’s disease (Early onset), excluding more controls

214

0.44

1.91

1.6

1.5

122.30

345.93

pmol/l

—

208

All dysplastic lesions of the cervix uteri, vagina or vulva

535

4748

1.12

1.90

1.4

81.12

100.07

pmol/l

0.94

528

4629

Type 1 diabetes, wide definition

136

1699

0.80

1.90

1.4

1.5

162.94

119.22

pmol/l

0.56

131

1653

Care involving use of rehabilitation procedures

556

5892

0.89

1.89

1.4

127.69

114.44

pmol/l

0.36

536

5772

Other arthrosis

563

3598

1.12

1.88

1.4

141.52

150.04

pmol/l

0.20

545

3513

Benign neoplasm: Ill-defined sites within the digestive system

2.93

1.88

1.5

1.3

61.00

65.84

pmol/l

—

Benign neoplasm: Peripheral nerves and autonomic nervous system

2.11

1.88

1.5

1.4

80.87

59.64

pmol/l

0.37

Cough

481

4096

1.13

1.87

1.4

133.48

141.35

pmol/l

0.15

463

4001

Inflammatory bowel disease

316

2727

1.16

1.87

1.3

1.4

71.86

129.18

pmol/l

6.39

307

2657

Dislocation, sprain and strain of joints and ligaments of knee

586

6055

0.90

1.87

1.3

1.4

97.29

119.14

pmol/l

1.18

566

5913

Tongue abnormality

492

1.39

1.87

1.4

1.5

125.07

238.51

pmol/l

1.58

479

Iron deficiency anaemia secondary to blood loss (chronic)

148

1192

1.25

1.86

1.5

1.4

174.54

176.87

pmol/l

0.02

142

1160

Benign neoplasm of eye and adnexa

526

1.38

1.85

1.6

1.4

95.09

72.53

pmol/l

0.65

510

Melanoma in situ, other sites/unspecified

4.32

1.84

1.0

1.2

104.00

56.03

pmol/l

—

Cervicalgia

236

1994

1.19

1.83

1.4

98.13

169.76

pmol/l

3.08

230

1931

Haemangioma and lymphangioma, any site

570

1.36

1.83

1.3

1.4

61.77

66.35

pmol/l

0.21

554

Covid-19 confirmed case

264

2251

1.18

1.83

1.6

1.4

125.22

132.10

pmol/l

0.10

257

2185

L04AX Other immunosuppressants

529

5904

0.89

1.82

1.4

137.16

136.86

pmol/l

0.00

512

5770

Diseases of appendix

876

7321

1.09

1.80

1.4

95.35

123.87

pmol/l

1.80

851

7149

Cardiac arrhythmias

875

5298

1.09

1.79

1.4

144.27

100.85

pmol/l

1.27

841

5191

Other congenital malformations of upper alimentary tract

2.50

1.78

1.2

104.10

99.96

pmol/l

—

Haemangioma, any site

522

1.37

1.77

1.3

1.4

62.30

67.46

pmol/l

0.22

508

Dental caries 2 and operation codes

992

7269

1.09

1.77

1.3

1.4

76.64

120.21

pmol/l

7.64

963

7091

Otitis externa

218

1836

1.19

1.77

1.5

1.4

147.79

137.33

pmol/l

0.11

209

1789

Antenatal screening

349

2252

0.87

1.76

1.4

54.40

80.48

pmol/l

2.67

339

2197

Crohn's disease of small intestine

549

1.36

1.75

1.4

1.5

71.70

139.85

pmol/l

1.42

538

Other joint disorders

1159

5720

1.08

1.75

1.4

117.47

114.29

pmol/l

0.08

1124

5571

Dental pulpitis 2, only avohilmo

851

3983

1.10

1.74

1.5

1.4

147.19

138.41

pmol/l

0.16

827

3882

Type 1 diabetes, strict definition, subgroup 1

555

0.66

1.74

1.4

69.57

78.29

pmol/l

0.14

539

Vascular dementia

249

0.50

1.73

1.8

1.4

82.38

297.03

pmol/l

2.71

240

142

1087

1.24

1.72

1.4

201.94

262.42

pmol/l

0.76

133

1047

Second line medication for Crohn's disease

547

6071

0.90

1.72

1.4

134.40

135.68

pmol/l

0.02

529

5931

Other gastritis (incl. Duodenitis)

199

1668

1.20

1.71

1.4

207.13

177.87

pmol/l

0.14

194

1615

Dental caries 2

1005

7301

1.08

1.70

1.3

1.4

77.37

122.69

pmol/l

7.82

976

7121

Neuroendocrine tumor and carcinoma of lung, excluding all cancers (controls excluding all cancers)

2.44

1.70

1.1

1.4

147.50

65.99

pmol/l

—

Type 1 diabetes, wide definition, subgroup 1

131

1617

0.81

1.68

1.5

165.61

117.57

pmol/l

0.60

126

1574

Triptan medication for migraine, min. 3 purchases

911

6628

1.09

1.68

1.4

70.71

109.86

pmol/l

5.84

886

6468

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

287

3308

0.86

1.68

1.3

1.5

73.19

106.29

pmol/l

3.02

280

3220

Other disorders of kidney and ureter

745

1.29

1.67

1.7

1.5

205.08

208.10

pmol/l

0.02

728

Presence of other devices

175

1452

1.21

1.67

1.4

154.14

200.21

pmol/l

0.75

167

1405

Oral corticosteroids

1309

7392

1.07

1.67

1.4

154.26

124.05

pmol/l

1.06

1280

7204

Other and unspecified injuries of ankle and foot

334

1.45

1.67

1.2

1.4

85.40

155.05

pmol/l

0.74

324

Gonarthrosis [arthrosis of knee](FG)

739

4761

0.91

1.66

1.4

199.32

140.94

pmol/l

0.94

721

4662

Reimbursement for rheumatic diseases

589

6482

0.90

1.65

1.4

154.83

138.73

pmol/l

0.25

571

6326

Nontoxic goitre/thyroid nodule

406

3603

1.13

1.65

1.5

1.4

114.05

170.92

pmol/l

2.88

398

3508

Ectopic pregnancy

317

2772

1.15

1.64

1.3

1.4

113.74

121.71

pmol/l

0.12

310

2716

Gestational [pregnancy-induced] hypertension

388

4359

0.88

1.62

1.3

1.4

63.75

101.49

pmol/l

5.96

376

4248

Dental caries 2, only avohilmo

990

7235

1.08

1.61

1.3

1.4

75.69

120.56

pmol/l

8.11

961

7059

Pneumothorax

262

1.50

1.60

1.5

187.51

235.04

pmol/l

0.21

257

Obesity related asthma

352

3102

1.14

1.60

1.5

1.4

145.61

137.56

pmol/l

0.13

343

3024

Gout, strict definition

420

1.38

1.60

1.5

257.41

243.86

pmol/l

0.07

411

Unspecified haematuria

243

1783

1.17

1.60

1.4

160.69

177.42

pmol/l

0.14

234

1736

Use of hypnotics and sedatives

1289

6965

1.07

1.59

1.4

132.47

127.58

pmol/l

0.13

1254

6805

Waldenstrom macroglobulinemia, lymphoplasmacytic lymphoma, excluding all cancers (controls excluding all cancers)

3.05

1.59

1.7

1.4

92.92

72.47

pmol/l

—

Other obstetric conditions, not elsewhere classified

527

3792

0.90

1.57

1.4

50.81

68.03

pmol/l

2.84

513

3692

Viral and other specified intestinal infections

192

1580

1.19

1.57

1.4

1.5

70.61

117.19

pmol/l

2.45

180

1533

Migraine without aura and triptan purchases

258

2231

1.16

1.57

1.4

1.5

59.17

100.74

pmol/l

3.11

249

2185

Other symptoms and signs involving cognitive functions and awareness

297

3186

0.87

1.56

1.3

1.4

148.28

175.92

pmol/l

0.57

287

3099

Insulin, combination of fast acting with intermediate-acting or long-acting

395

4090

0.89

1.56

1.4

1.5

179.14

148.37

pmol/l

0.70

380

3981

Other specified/unspecified arthritis

232

2698

0.86

1.55

1.4

102.63

143.83

pmol/l

1.88

224

2625

Benign neoplasm: Spinal cord

2.06

1.55

2.3

1.3

62.15

56.78

pmol/l

0.26

Benign neoplasm: Skin of trunk

224

1.53

1.55

1.7

1.4

137.61

55.37

pmol/l

1.40

219

Urticaria and erythema

456

4094

1.12

1.53

1.4

1.5

110.61

126.04

pmol/l

0.42

440

3991

All influenza (not pneumonia)

117

942

1.25

1.53

1.9

1.4

232.25

163.29

pmol/l

0.31

112

918

Dental pulpitis 2

832

3921

1.09

1.52

1.5

1.4

149.25

137.74

pmol/l

0.22

809

3821

Nerve, nerve root and plexus disorders

1271

7478

1.07

1.51

1.4

137.55

128.64

pmol/l

0.20

1238

7298

Sleep apnoea

901

6595

0.93

1.51

1.4

130.67

139.25

pmol/l

0.21

875

6448

Acute appendicitis, no complications

635

5787

1.10

1.51

1.4

102.07

113.72

pmol/l

0.36

617

5653

Artrosis, including avohilmo

896

5309

0.92

1.48

1.4

138.32

124.43

pmol/l

0.26

875

5190

Other arrhythmias

770

5430

1.09

1.48

1.4

121.40

130.88

pmol/l

0.24

742

5310

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

515

3692

0.90

1.48

1.4

50.34

61.72

pmol/l

2.35

501

3593

Abrasion of teeth

324

2097

1.14

1.48

1.5

80.64

106.27

pmol/l

1.83

315

2051

Benign neoplasm: Retina

2.56

1.46

1.4

1.3

224.00

64.18

pmol/l

—

Other heart diseases, wide

1182

6860

1.07

1.46

1.4

150.05

120.14

pmol/l

1.01

1140

6705

All influenza

196

1669

1.18

1.45

1.7

1.4

197.39

157.68

pmol/l

0.29

186

1623

Cutaneous abscess, furuncle and carbuncle

227

1958

1.16

1.44

1.5

1.4

105.49

131.61

pmol/l

0.79

221

1906

Striking against or struck by other objects

244

2115

1.16

1.43

1.3

1.4

84.09

122.61

pmol/l

1.76

235

2056

Abnormal serum enzyme levels

700

1.27

1.42

1.4

1.5

116.16

187.99

pmol/l

0.94

687

Appendicitis, broad definition

858

7279

1.08

1.41

1.4

96.09

124.01

pmol/l

1.69

833

7109

Severe visual impairment, binocular

2.47

1.40

1.4

1.6

110.29

98.85

pmol/l

—

Melanocytic naevi

328

2909

1.13

1.40

1.5

1.4

83.66

127.66

pmol/l

2.31

319

2829

Carcinoma in situ of skin of scalp and neck

2.43

1.39

1.3

1.5

228.43

78.83

pmol/l

—

Retention of urine

159

1127

1.19

1.39

1.4

105.41

176.98

pmol/l

2.36

154

1096

Sulfasalazine

259

2957

0.87

1.38

1.4

173.29

134.88

pmol/l

0.31

247

2880

Visual disturbances

498

4523

1.10

1.38

1.4

121.36

141.31

pmol/l

0.59

484

4409

Fall on same level

1302

7728

0.94

1.38

1.4

116.71

123.66

pmol/l

0.29

1260

7540

Acute suppurative otitis media

283

2323

1.14

1.37

1.4

1.5

72.33

94.17

pmol/l

0.83

264

2263

Benign neoplasm: Connective and other soft tissue of abdomen

3.04

1.37

1.8

1.3

81.00

56.06

pmol/l

—

Presence of cardiac and vascular implants and grafts

187

1657

0.85

1.37

1.5

1.4

176.08

228.43

pmol/l

0.72

181

1613

Other obstructive and reflux uropathy

323

1.40

1.36

2.0

1.4

307.65

117.80

pmol/l

0.90

314

Gout, idiopatic and unspecified

714

1.26

1.36

1.6

1.5

198.34

230.14

pmol/l

0.28

689

Other benign neoplasm of uterus: Cervix uteri

2.02

1.35

1.5

1.3

155.44

56.33

pmol/l

0.46

Femoral hernia

284

0.59

1.34

1.2

1.4

62.29

245.37

pmol/l

2.43

279

Disturbances of smell and taste

376

1.37

1.33

1.4

1.5

88.47

244.29

pmol/l

2.18

371

Benign neoplasm: Endocrine gland, other/unspecified

2.58

1.32

3.2

1.2

45.83

68.54

pmol/l

—

Malignant neoplasm of breast, HER-negative

299

2648

1.13

1.32

1.6

1.4

193.87

177.18

pmol/l

0.20

290

2588

Benign neoplasm: Bladder

2.52

1.30

1.3

65.33

52.29

pmol/l

—

Dental caries 3

983

4691

1.07

1.30

1.5

1.4

148.46

132.50

pmol/l

0.35

952

4572

Schizophrenia or delusion

240

2740

0.87

1.30

1.5

1.4

116.80

129.17

pmol/l

0.33

232

2671

Diseases of oral cavity, salivary glands and jaws

1109

5335

1.07

1.28

1.4

141.76

131.30

pmol/l

0.25

1074

5209

Endovascular or surgical operations to intracerebral aneurysms

507

0.71

1.28

1.2

1.6

87.36

241.95

pmol/l

2.95

496

Asthma mixed form (mode), excluding more controls

448

0.69

1.27

1.6

1.5

64.62

142.13

pmol/l

1.42

438

Asthma mixed form (mode)

448

0.69

1.27

1.6

1.4

64.62

143.34

pmol/l

1.46

438

Struck by thrown, projected or falling objec

230

0.56

1.27

1.5

1.4

51.62

117.83

pmol/l

0.81

223

Schizophrenia, schizotypal and delusional disorders

241

2745

0.88

1.26

1.5

1.4

118.19

128.95

pmol/l

0.28

233

2676

Excessive attrition of teeth

471

2319

1.10

1.26

1.4

1.5

87.53

100.64

pmol/l

0.64

453

2263

Non-allergic asthma (mode), excluding more controls

154

1795

0.85

1.26

1.5

1.4

76.13

139.91

pmol/l

4.79

148

1755

Allergic conjunctivitis

720

7633

0.93

1.26

1.4

97.54

124.51

pmol/l

1.63

707

7437

Acute appendicitis

796

6989

1.08

1.25

1.4

95.32

122.61

pmol/l

1.51

775

6825

Schizophrenia or delusion, excluding more controls

240

2711

0.88

1.25

1.5

1.4

116.80

125.05

pmol/l

0.21

232

2645

Other specified/unspecified hearing loss

516

0.71

1.24

1.4

1.5

261.47

210.74

pmol/l

0.19

505

Malignant melanoma of skin

680

1.25

1.24

1.3

1.5

92.31

218.90

pmol/l

3.24

662

Other and unspecified urticaria

235

2061

1.14

1.23

1.4

109.95

135.00

pmol/l

0.46

227

2006

Gastric ulcer

121

1005

1.21

1.23

1.4

1.5

164.57

194.39

pmol/l

0.36

113

975

Diabetes, insulin treatment (Kela reimbursement)

1047

6816

0.94

1.23

1.4

179.91

130.35

pmol/l

1.83

1015

6661

Malignant cancer of tonsil and base of tongue, excluding all cancers (controls excluding all cancers)

1.98

1.22

1.2

1.4

474.36

64.52

pmol/l

0.76

IBD patients in KELA-register

220

1922

1.15

1.22

1.4

1.5

59.52

124.54

pmol/l

6.26

214

1871

Urticaria

373

3367

1.11

1.21

1.4

1.5

108.39

124.13

pmol/l

0.38

358

3283

Non-allergic asthma (mode)

154

1788

0.85

1.21

1.5

1.4

76.13

142.90

pmol/l

5.12

148

1744

Dental caries, including avohilmo

914

4365

1.07

1.21

1.5

1.4

148.32

135.92

pmol/l

0.24

888

4254

Chronic kidney disease

149

1258

1.18

1.20

1.8

1.4

379.68

204.66

pmol/l

3.66

136

1223

Dental caries 3 and operation codes

1068

5146

1.07

1.20

1.5

1.4

156.00

138.60

pmol/l

0.33

1034

5017

Disorders of breast

868

7528

1.07

1.20

1.4

140.62

132.27

pmol/l

0.14

845

7350

Other disorders of bladder

532

1.28

1.19

1.5

84.99

184.00

pmol/l

2.55

522

Autism spe, excluding more controls

117

1.64

1.18

1.4

114.02

51.76

pmol/l

0.43

112

Neurological diseases

1200

5698

1.06

1.18

1.4

117.98

123.74

pmol/l

0.15

1162

5559

Systemic connective tissue disorders

417

3792

1.10

1.18

1.6

1.4

110.47

158.62

pmol/l

3.21

408

3692

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

290

2587

1.12

1.17

1.3

1.4

90.56

116.78

pmol/l

1.19

280

2520

Malignant neoplasm of rectum

437

1.31

1.17

1.3

1.5

178.33

270.25

pmol/l

0.38

429

Rheumatoid arthritis, including avohilmo

370

4086

0.90

1.17

1.5

1.4

212.32

151.95

pmol/l

0.73

361

3979

Dental caries 1 and operation codes

1008

4854

1.07

1.16

1.4

147.48

141.56

pmol/l

0.12

979

4732

2.56

1.16

1.6

75.40

49.33

pmol/l

—

Soft tissue disorders

1302

6399

1.06

1.16

1.5

1.4

125.96

123.34

pmol/l

0.06

1264

6238

Superficial injury of head

199

1734

1.15

1.16

1.5

1.4

132.13

158.52

pmol/l

0.38

193

1684

Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)

1.82

1.15

2.0

1.4

134.54

60.46

pmol/l

0.61

Dental caries 3, only avohilmo

989

4747

1.07

1.15

1.5

1.4

145.60

134.15

pmol/l

0.24

958

4628

Dental caries 1

913

4369

1.07

1.15

1.5

1.4

148.45

135.85

pmol/l

0.24

887

4258

366

3621

0.90

1.15

1.5

1.4

180.65

121.30

pmol/l

0.86

356

3529

ILD medications: prednisolone, methylprednisolone, prednisone

1358

7274

1.06

1.15

1.4

130.99

121.79

pmol/l

0.29

1330

7089

Pregnancy hypertension

680

6586

0.93

1.14

1.4

77.06

110.58

pmol/l

5.23

664

6436

Other disorders of bone density and structure

208

1.46

1.14

1.4

66.15

233.83

pmol/l

1.35

203

Inflammatory bowel disease, strict (require KELA)

220

1934

1.14

1.13

1.4

1.5

59.52

123.61

pmol/l

6.17

214

1884

Other arthritis (FG)

275

3080

0.89

1.13

1.4

127.64

138.60

pmol/l

0.19

266

3001

Benign neoplasm: Caecum

626

1.25

1.13

1.5

211.02

232.75

pmol/l

0.12

610

Other headache syndromes

593

5493

1.08

1.12

1.4

98.77

134.16

pmol/l

1.19

579

5368

Parodontitis or/and operation codes

675

4317

0.93

1.11

1.4

157.05

111.66

pmol/l

1.20

656

4213

Gonarthrosis, primary, with knee surgery

512

3847

1.09

1.11

1.4

238.97

172.02

pmol/l

0.87

500

3751

Gonarthrosis

635

3928

0.93

1.11

1.4

171.73

143.66

pmol/l

0.50

618

3842

Adenocarcinoma and papilloma adenocarcinoma of rectum

415

1.31

1.10

1.3

1.5

257.72

258.87

pmol/l

0.00

405

Nontoxic multinodular goitre

260

2317

1.13

1.10

1.5

1.4

133.82

176.69

pmol/l

1.05

254

2253

Parodontitis or operation codes

883

6922

0.94

1.10

1.4

162.37

136.65

pmol/l

0.59

856

6763

Arthrosis

754

4440

0.93

1.09

1.4

128.21

133.45

pmol/l

0.10

733

4338

All dysplastic lesions of the cervix uteri

457

4187

1.09

1.4

81.23

97.83

pmol/l

0.65

451

4082

Familial hypercholesterolemia

801

1.21

1.08

1.8

1.5

254.92

210.48

pmol/l

0.31

779

Benign neoplasm of bone and articular cartilage

684

1.23

1.08

1.5

72.53

161.48

pmol/l

2.37

674

Other/unspecified disorders of vestibular function

267

0.63

1.08

1.2

1.5

196.18

269.23

pmol/l

0.30

261

Labour and delivery complicated by fetal stress [distress]

392

2870

0.91

1.08

1.4

58.96

64.34

pmol/l

0.26

382

2796

Symptoms and signs involving the skin and subcutaneous tissue

797

7435

1.07

1.08

1.4

125.46

131.63

pmol/l

0.15

776

7252

Parodontitis

883

6921

0.94

1.07

1.4

162.37

136.67

pmol/l

0.59

856

6762

Type1 diabetes, definitions combined, early onset

464

0.73

1.06

1.5

1.4

72.47

54.76

pmol/l

0.51

451

Anuria and oliguria

2.15

1.06

1.0

1.5

92.29

81.50

pmol/l

—

Diarrhoea and gastroenteritis of presumed infectious origin

764

6499

1.07

1.06

1.4

143.63

118.73

pmol/l

0.51

727

6339

Hydrocephalus

431

0.72

1.06

1.6

1.5

203.26

235.30

pmol/l

0.10

423

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

218

1927

1.13

1.06

1.4

1.5

153.26

143.82

pmol/l

0.07

212

1883

Post-traumatic stress disorder

108

905

1.20

1.05

1.4

67.40

93.37

pmol/l

0.61

100

884

Adjustment and management of implanted device

822

1.21

1.05

1.6

1.4

253.83

189.10

pmol/l

0.35

805

Generalized anxiety disorder

185

1619

1.15

1.05

1.4

77.76

109.09

pmol/l

0.93

179

1574

Maternal care for known or suspected fetal abnormality and damage

233

2329

0.89

1.05

1.3

1.4

55.47

71.46

pmol/l

1.67

224

2271

Inflammatory bowel disease treatment related agents

1404

7591

1.05

1.4

139.63

121.88

pmol/l

0.58

1373

7394

Wide developmental disorders, excluding more controls

136

1.54

1.04

1.4

110.35

50.19

pmol/l

0.47

130

Cardiomyopathies, Secondary/extrinsic

2.30

1.04

2.4

1.3

103.80

77.56

pmol/l

—

Pilonidal cyst

517

1.26

1.03

1.5

1.4

126.82

96.62

pmol/l

0.17

505

Subjective visual disturbances

259

2319

1.12

1.02

1.3

1.4

115.32

160.10

pmol/l

1.01

248

2252

Fitting and adjustment of other devices

250

2076

1.12

1.02

1.6

1.4

170.34

163.66

pmol/l

0.08

237

2037

Chronic gastritis

246

2196

1.12

1.02

1.6

1.4

166.64

188.24

pmol/l

0.26

240

2133

Dental caries 1, only avohilmo

920

4428

1.06

1.02

1.5

1.4

147.39

137.58

pmol/l

0.18

891

4317

Deep bite

748

0.80

1.02

1.4

1.5

94.50

141.72

pmol/l

0.45

730

Other other unspecified disorders of the circulatory system

230

1.40

1.02

1.5

111.15

287.72

pmol/l

1.34

225

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

701

7356

0.94

1.01

1.4

96.24

125.45

pmol/l

1.82

689

7161

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

287

3180

0.90

1.01

1.3

1.4

73.19

100.88

pmol/l

2.39

280

3096

Other CVD

116

982

1.18

1.01

1.4

1.5

163.24

198.18

pmol/l

0.40

111

950

Polyarthropathies

698

4972

0.93

1.00

1.5

1.4

166.21

124.08

pmol/l

0.99

679

4853

Rotator cuff syndrome

577

4608

0.93

1.00

1.4

136.92

150.17

pmol/l

0.36

562

4510

Chronic periodontitis, including avohilmo

880

6902

0.94

0.99

1.4

151.50

138.34

pmol/l

0.30

853

6744

Bleeding

677

5264

0.93

0.99

1.6

1.4

211.03

146.96

pmol/l

1.23

651

5134

Malignant neoplasm of gallbladder, excluding all cancers (controls excluding all cancers)

2.20

0.98

1.2

1.3

92.80

75.84

pmol/l

—

Seropositive rheumatoid arthritis

253

2810

0.90

0.98

1.5

1.4

231.66

161.96

pmol/l

0.58

248

2744

Polyarthrosis

247

2121

1.12

0.98

1.5

155.96

189.42

pmol/l

0.69

241

2065

Benign paroxysmal vertigo

305

2765

1.11

0.97

1.5

1.4

138.75

179.65

pmol/l

1.04

295

2690

Used for control exclusion in common control thyroid runs

1251

6031

1.05

0.97

1.5

1.4

121.70

116.27

pmol/l

0.15

1216

5875

COPD/asthma/ILD related infections

1428

6823

1.05

0.97

1.5

1.4

108.73

126.93

pmol/l

1.19

1391

6662

COPD/asthma related infections

1428

6823

1.05

0.97

1.5

1.4

108.73

126.93

pmol/l

1.19

1391

6662

Use of glatiramer acetate

198

0.60

0.97

1.2

1.4

82.32

117.13

pmol/l

0.25

192

Alzheimer’s disease (undefined)

0.00

0.96

0.0

1.5

—

252.20

—

Crohn disease

122

1043

1.17

0.96

1.3

1.5

70.33

149.24

pmol/l

3.32

117

1015

Seborrhoeic keratosis

196

1734

1.13

0.96

1.4

122.85

207.94

pmol/l

2.37

190

1690

Ulcerative rectosigmoiditis

613

1.23

0.96

1.4

1.5

58.06

127.28

pmol/l

2.34

603

Heart failure and antihypertensive medication

207

1210

1.13

0.96

1.5

1.4

266.12

152.21

pmol/l

1.20

200

1185

Mycoses

238

2132

1.12

0.95

1.5

1.4

144.17

153.00

pmol/l

0.09

229

2071

Benign neoplasm: Parathyroid gland

1.80

0.95

1.7

1.4

306.82

62.84

pmol/l

0.94

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

1023

6586

0.95

0.94

1.4

179.60

124.86

pmol/l

2.10

991

6438

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

768

7129

0.94

1.4

82.14

115.34

pmol/l

5.22

750

6963

Benign neoplasm: Rectum/anal canal icd-9

2.24

0.94

1.3

1.5

112.42

74.83

pmol/l

—

Other and unspecified abdominal hernia

269

1.35

0.93

1.3

1.4

261.17

246.09

pmol/l

0.03

263

Diseases of external ear

291

2640

1.10

0.92

1.4

137.76

151.49

pmol/l

0.20

278

2567

Suicide or other Intentional self-harm

210

2352

0.89

0.92

1.4

81.60

122.70

pmol/l

2.62

205

2296

Anterior Iridocyclitis

187

1656

1.13

0.92

1.4

232.58

154.42

pmol/l

0.77

180

1617

Disorders of conjunctiva

1040

8273

1.05

0.92

1.4

101.74

128.11

pmol/l

1.83

1020

8052

Other and unspecified nonorganic psychotic disorders

143

1640

0.87

0.91

1.5

89.04

124.10

pmol/l

1.14

137

1600

Abscess of Bartholin gland

314

1.32

0.91

1.6

1.4

83.10

131.70

pmol/l

0.57

307

Single delivery by caesarean section

318

2018

0.91

1.4

54.12

82.06

pmol/l

3.05

306

1966

Diabetic retinopathy

176

1260

0.88

0.91

1.4

204.09

194.73

pmol/l

0.09

169

1221

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

395

0.73

0.91

1.4

72.31

115.22

pmol/l

0.70

382

Long labour

385

3649

0.92

0.90

1.4

1.5

92.95

94.50

pmol/l

0.02

380

3565

Dental caries 3 and operation codes, only avohilmo

386

1778

1.09

0.90

1.5

1.4

156.27

112.05

pmol/l

0.58

377

1726

Perineal laceration during delivery

241

2381

0.90

0.89

1.4

1.5

65.01

84.08

pmol/l

0.55

234

2316

Hypokalaemia

106

904

1.18

0.88

1.7

1.5

156.35

171.51

pmol/l

0.19

101

882

Panic disorder

178

1577

1.13

0.88

1.4

1.5

68.02

112.41

pmol/l

2.24

172

1535

Hypo-osmolality and hyponatraemia

136

1179

1.15

0.88

1.7

1.5

372.08

193.89

pmol/l

0.75

127

1148

Bacterial Sepsis

302

2447

1.10

0.88

1.6

1.4

245.77

185.55

pmol/l

0.90

291

2379

Dislocation, sprain and strain of joints and ligaments at neck level

158

1389

1.14

0.88

1.4

1.5

75.81

119.44

pmol/l

1.57

153

1355

Postpartum hemorraghe, parous women as controls

429

3477

1.08

0.88

1.4

55.22

89.63

pmol/l

4.86

418

3397

Other keratitis

103

877

1.18

0.88

1.5

90.34

159.24

pmol/l

1.77

103

858

Candidiasis

144

1259

1.15

0.87

1.5

155.11

155.02

pmol/l

0.00

138

1232

Melanoma in situ of other and unspecified parts of face

2.02

0.87

1.3

71.00

75.38

pmol/l

—

Gilbert syndrome

1.84

0.86

1.5

1.3

78.38

300.49

pmol/l

—

Any mental disorder

1405

6734

1.05

0.86

1.5

1.4

143.82

125.75

pmol/l

0.51

1366

6573

Erosion of teeth, including avohilmo

216

1872

1.12

0.86

1.3

1.5

76.37

90.20

pmol/l

0.42

210

1828

Contact with other hot fluids

204

0.63

0.86

1.5

1.4

39.92

123.90

pmol/l

0.97

199

Superficial injury of hip and thigh

110

943

1.17

0.86

1.3

1.5

121.91

182.73

pmol/l

0.84

103

917

Medical abortion

1113

6345

0.95

0.86

1.5

1.4

120.27

129.91

pmol/l

0.30

1072

6183

Viral infections characterized by skin and mucous membrane lesions

387

3570

1.08

0.86

1.5

1.4

102.56

140.74

pmol/l

2.50

378

3467

Pregnancy, childbirth and the puerperium

455

2566

0.93

0.85

1.5

171.32

156.25

pmol/l

0.15

441

2487

Sciatica+with lumbago

597

5317

1.07

0.85

1.4

120.84

137.59

pmol/l

0.25

575

5189

Acute bronchitis

363

3277

1.09

0.84

1.5

154.72

156.60

pmol/l

0.02

352

3184

Adrenocortical insufficiency

274

1.32

0.84

1.4

75.42

226.16

pmol/l

1.70

268

Allergic asthma (mode), excluding more controls

306

2748

1.09

0.84

1.4

101.55

105.97

pmol/l

0.08

300

2685

Autoimmune diseases

1329

6494

1.05

0.84

1.5

1.4

122.29

117.90

pmol/l

0.12

1287

6328

Dialysis, with operation codes

587

1.21

0.84

1.7

1.5

520.88

206.57

pmol/l

3.31

577

Haemorrhage in early pregnancy

513

4679

1.07

0.83

1.4

92.21

111.25

pmol/l

0.87

500

4572

Mental and behavioural disorders associated with the puerperium

165

0.60

0.83

1.4

68.40

63.97

pmol/l

—

160

Left ventricular outflow tract obstruction, narrow definition

214

1.36

0.82

1.3

1.4

77.86

155.14

pmol/l

0.73

208

Dental operations, only avohilmo

759

3670

1.06

0.82

1.5

1.4

158.73

152.34

pmol/l

0.10

741

3586

Etanercept

577

0.79

0.82

1.6

1.5

65.55

174.83

pmol/l

2.53

569

Temporomandibular joint disorders, including avohilmo

602

5654

1.06

0.81

1.4

69.78

110.44

pmol/l

6.11

582

5504

Symptoms and signs involving speech and voice

298

3251

0.91

0.81

1.4

194.56

150.13

pmol/l

0.46

287

3162

Autism spe

130

1.47

0.81

1.4

1.3

114.02

45.01

pmol/l

0.49

124

Autism

130

1.47

0.81

1.4

1.3

114.02

44.62

pmol/l

0.50

124

Haemorrhage from respiratory passages

249

2097

1.10

0.81

1.5

1.4

284.83

185.85

pmol/l

0.64

239

2046

Allergic asthma (mode)

306

2755

1.09

0.81

1.4

101.55

106.74

pmol/l

0.09

300

2688

LSIL lesion of the cervix uteri, vagina or vulva

232

2102

1.11

0.80

1.3

1.5

71.41

111.22

pmol/l

2.44

227

2056

Benign neoplasm of other and unspecified intrathoracic organs

1.74

0.80

1.0

1.3

62.60

62.88

pmol/l

—

Codes for special purposes

476

4444

1.07

0.80

1.5

1.4

119.90

121.88

pmol/l

0.04

465

4318

Provisional assignment of new diseases of uncertain etiology

475

4435

1.07

0.80

1.5

1.4

119.95

122.00

pmol/l

0.04

464

4309

Epilepsy

223

2456

0.90

0.79

1.4

140.12

147.56

pmol/l

0.11

218

2390

Suppurative and unspecified otitis media

384

3153

1.08

0.79

1.4

1.5

79.10

101.33

pmol/l

0.87

361

3069

Dental pulpitis 3, only avohilmo

105

659

1.17

0.79

1.6

1.4

42.13

45.74

pmol/l

0.52

622

Alzheimer’s disease (undefined), excluding more controls

0.00

0.79

0.0

1.5

—

288.21

—

Cardiac arrest

233

0.70

0.78

1.7

1.4

172.32

190.04

pmol/l

0.09

226

Somatoform disorder

191

1715

1.12

0.78

1.5

1.4

184.52

137.27

pmol/l

0.41

183

1670

Viral haemorrhagic fevers, not elsewhere classified/unspecified

465

1.23

0.78

1.4

1.5

93.76

199.13

pmol/l

1.57

458

Systemic lupus erythematosus

367

1.26

0.78

1.5

1.4

160.70

187.77

pmol/l

0.16

360

Maternal care related to the fetus and amniotic cavity and possible delivery problems

766

4756

0.95

0.77

1.4

72.30

111.27

pmol/l

3.92

751

4645

Dental operations

713

3456

1.06

0.77

1.5

1.4

150.59

152.91

pmol/l

0.03

696

3378

All dysplastic lesions of the vagina

323

1.28

0.77

1.3

1.5

159.88

200.71

pmol/l

0.19

316

Fibroblastic disorders

182

1631

1.12

0.77

1.4

180.34

154.43

pmol/l

0.25

175

1590

Benign neoplasm: Connective and other soft tissue of thorax

0.00

0.77

0.0

1.4

—

89.13

—

Chondrocostal junction syndrome [Tietze]

332

1.27

0.76

1.5

59.88

215.22

pmol/l

2.36

326

Chronic myeloid leukaemia, excluding all cancers (controls excluding all cancers)

1.78

0.76

1.3

1.4

68.52

65.29

pmol/l

—

Spondylosis

528

4249

1.07

0.76

1.5

1.4

152.36

155.30

pmol/l

0.03

514

4151

Molar incisor enamel hypoplasia

170

0.63

0.76

1.5

1.3

87.09

48.53

pmol/l

0.48

160

Disorders of porphyrin and bilirubin metabolism

1.66

0.76

2.0

1.4

71.09

230.70

pmol/l

0.52

Psoriasis

212

2339

0.90

0.75

1.4

117.70

151.95

pmol/l

0.65

206

2273

Open wound of wrist and hand

320

2924

1.08

0.74

1.6

1.5

82.92

111.79

pmol/l

1.65

308

2839

Gout, unspecified

568

1.20

0.74

1.4

1.5

164.12

238.65

pmol/l

1.05

554

Supervision of normal pregnancy

358

2209

0.92

0.74

1.4

46.91

79.95

pmol/l

4.50

352

2154

Other/unspecified seropositive rheumatoid arthritis

247

2702

0.91

0.74

1.5

1.4

234.81

167.92

pmol/l

0.53

242

2630

Hypoplasia of dental enamel , including avohilmo

158

0.62

0.74

1.5

1.3

93.10

48.77

pmol/l

—

148

Other external causes of accidental injury

1074

5623

0.96

0.73

1.4

116.36

128.35

pmol/l

0.33

1047

5500

Lyme disease

249

2276

1.10

0.73

1.4

1.5

107.55

164.00

pmol/l

1.78

242

2212

Wide developmental disorders

150

1.41

0.73

1.4

110.35

52.62

pmol/l

0.44

142

Arthropathies

1173

5720

1.04

0.73

1.5

1.4

108.23

114.29

pmol/l

0.18

1141

5571

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

307

1.27

0.73

1.4

195.10

81.81

pmol/l

0.75

294

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

620

0.84

0.73

1.7

1.4

112.70

184.99

pmol/l

2.46

605

Bitten or struck by other mammals

121

1063

1.14

0.73

1.5

1.4

91.12

132.74

pmol/l

0.67

112

1036

Hyperfunction of pituitary gland

490

0.79

0.72

1.3

1.4

52.08

137.32

pmol/l

1.78

478

Seropositive rheumatoid arthritis, strict definition

131

1480

0.88

0.72

1.4

286.91

166.90

pmol/l

0.56

126

1447

Anogenital herpesviral [herpes simplex] infection

654

1.18

0.72

1.5

1.4

68.63

101.00

pmol/l

0.58

638

Melanocytic naevi of lower limb, including hip

380

1.24

0.72

1.4

81.21

167.68

pmol/l

1.03

374

Contusion of toe(s) without damage to nail

220

1.33

0.72

1.5

1.4

145.97

108.11

pmol/l

0.14

214

Residual foreign body in soft tissue

299

0.73

0.72

1.8

1.5

55.00

145.92

pmol/l

1.85

294

Osteopathies and chondropathies

578

5174

1.06

0.72

1.4

122.51

155.39

pmol/l

2.16

559

5039

Mature T/NK-cell lymphomas, hilmo, excluding all cancers

1.76

0.71

1.1

1.3

89.71

57.00

pmol/l

—

Nondiabetic hypoglycaemic coma

1.96

0.71

1.0

1.3

310.40

60.29

pmol/l

—

Cerebrovascular diseases (FINNGEN)

295

2289

0.92

0.71

1.5

1.4

139.42

117.48

pmol/l

0.35

289

2242

Specific personality disorders

226

2476

0.91

0.71

1.5

121.38

108.05

pmol/l

0.14

220

2415

Disorders of magnesium metabolism

1.73

0.70

1.4

182.57

323.16

pmol/l

—

Iridocyclitis

208

1890

1.10

0.70

1.4

222.15

151.98

pmol/l

0.76

198

1842

Disorders of lens

572

3823

0.94

0.70

1.4

169.72

157.29

pmol/l

0.21

554

3734

Failed induction of labour

805

1.16

0.70

1.3

1.5

66.51

58.54

pmol/l

0.14

780

Diseases of salivary glands

207

1882

1.10

0.69

1.4

1.5

132.96

143.77

pmol/l

0.16

200

1834

Other maternal disorders predominantly related to pregnancy

1019

6685

0.96

0.69

1.5

1.4

96.11

116.35

pmol/l

1.11

997

6530

Parodontitis and operation codes

837

6816

0.95

0.69

1.4

152.68

139.19

pmol/l

0.29

812

6660

Other specified and unspecified disorders of choroid

1.89

0.69

1.2

1.4

40.80

82.87

pmol/l

—

Other fibroblastic disorders

1.88

0.69

1.4

1.7

55.60

69.81

pmol/l

—

Substance abuse, excluding more controls

396

3708

0.93

0.69

1.5

1.4

136.23

117.72

pmol/l

0.32

388

3614

Disorders of adult personality and behaviour

278

3013

0.92

0.69

1.5

110.75

103.43

pmol/l

0.09

271

2933

Paroxysmal tachycardia

242

1873

1.09

0.69

1.4

117.95

118.05

pmol/l

0.00

233

1829

Other spirochaetal diseases

250

2295

1.09

0.69

1.4

1.5

107.47

163.00

pmol/l

1.75

243

2230

Localized swelling, mass and lump of skin and subcutaneous tissue

302

2796

1.08

0.68

1.4

148.11

144.91

pmol/l

0.04

293

2716

Other and unspecified visual disturbances

779

1.16

0.68

1.4

1.5

96.49

192.15

pmol/l

2.25

762

Assault by hanging, strangulation and suffocation

1.83

0.67

1.4

1.5

161.40

51.74

pmol/l

—

Benign neoplasm: Female genital organ, unspecified

1.82

0.67

1.4

1.3

65.20

57.69

pmol/l

—

Internal derangement of knee

389

3629

1.07

0.67

1.3

1.4

109.91

134.07

pmol/l

0.74

373

3539

Senile cataract

501

3298

0.94

0.66

1.4

1.5

191.49

168.60

pmol/l

0.34

484

3224

Pre-eclampsia or poor fetal growth

488

5160

0.94

0.66

1.4

81.46

102.94

pmol/l

1.83

482

5025

Malignant neoplasm of nasal cavity and middle ear, excluding all cancers (controls excluding all cancers)

1.80

0.66

1.2

1.3

52.80

58.36

pmol/l

—

Gangrene, not elsewhere classified

1.80

0.66

2.0

1.2

64.40

427.34

pmol/l

—

Gingivitis and periodontal diseases

1076

5329

1.04

0.66

1.4

166.61

131.27

pmol/l

0.78

1042

5203

Diseases of the ear and mastoid process

1490

7279

1.04

0.66

1.5

1.4

107.96

126.70

pmol/l

1.16

1438

7111

Nonorganic sleeping disorders, excluding more controls

192

1745

1.10

0.66

1.4

82.86

121.18

pmol/l

1.44

184

1701

Other disorders of choroid

1.55

0.66

1.2

1.4

142.78

231.10

pmol/l

0.23

341

3360

0.93

0.66

1.5

1.4

185.85

123.74

pmol/l

0.83

331

3273

Atopic dermatitis

737

5995

1.05

0.64

1.4

90.01

106.77

pmol/l

0.53

716

5843

Pain in thoracic spine

165

1491

1.11

0.64

1.5

1.4

67.22

150.77

pmol/l

6.40

160

1449

Pustulosis palmaris et plantaris

393

0.78

0.64

1.2

1.5

114.61

212.30

pmol/l

1.03

387

Leukaemia of unspecified cell type

1.74

0.64

1.2

1.3

67.40

56.26

pmol/l

—

Chronic tubulo-interstitial nephritis

305

1.25

0.64

1.4

244.77

176.55

pmol/l

0.38

298

Other acute lower respiratory infections

463

4165

1.06

0.63

1.5

1.4

137.12

140.73

pmol/l

0.04

448

4036

L04AC Interleukin inhibitors

369

1.22

0.63

1.3

1.5

72.07

181.20

pmol/l

1.40

362

Adhesive capsulitis of shoulder

173

1570

1.10

0.63

1.4

153.58

161.08

pmol/l

0.08

166

1527

Other specified and unspecified disorders of lens

1.65

0.62

1.6

1.3

128.13

504.58

pmol/l

—

Malignant neoplasm of tongue, excluding all cancers (controls excluding all cancers)

1.56

0.62

1.5

1.3

79.18

60.90

pmol/l

1.16

Personality disorders

265

2860

0.93

0.62

1.5

114.02

108.58

pmol/l

0.06

258

2791

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

247

2673

0.92

0.62

1.5

1.4

234.81

167.23

pmol/l

0.53

242

2601

Obstetric embolism

0.00

0.62

0.0

1.3

—

73.35

—

Foreign body on external eye

461

1.19

0.61

1.4

1.5

92.18

148.91

pmol/l

0.70

451

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

504

4669

1.06

0.61

1.3

1.4

97.87

137.33

pmol/l

2.82

490

4568

Bronchiectasis

533

0.82

0.61

2.0

1.4

113.30

222.42

pmol/l

2.28

518

Seropositive rheumatoid arthritis, wide

253

2733

0.92

0.61

1.5

1.4

231.66

167.09

pmol/l

0.52

248

2661

Statin medication

864

5056

0.96

0.61

1.4

173.81

113.89

pmol/l

1.64

843

4951

Fitting and adjustment of external prosthetic device

0.00

0.61

0.0

1.2

—

88.78

—

Glaucoma secondary to drugs

0.00

0.60

0.0

1.5

—

557.74

—

Benign neoplasm: Connective and other soft tissue of thorax

0.00

0.60

0.0

1.3

—

56.95

—

SLE, strict definition

344

1.23

0.60

1.4

1.5

171.64

180.53

pmol/l

0.04

337

SLE, ICD10

344

1.23

0.60

1.4

1.5

171.64

180.53

pmol/l

0.04

337

Plasmodium falciparum malaria

0.00

0.60

0.0

1.5

—

56.50

—

Postpartum haemorrhage due to retained placenta

190

1738

1.10

0.60

1.4

52.00

83.76

pmol/l

2.62

185

1698

Complications of other internal prosthetic devices, implants and grafts

236

1.28

0.60

2.1

1.4

94.40

228.43

pmol/l

1.53

231

Neuroendocrine tumor and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

0.00

0.60

0.0

1.3

—

68.18

—

Other systemic involvement of connective tissue

313

2923

1.07

0.59

1.5

1.4

106.35

166.40

pmol/l

3.64

307

2839

Cleft lip

0.00

0.59

0.0

1.3

—

49.55

—

Other cestode infections

0.00

0.59

0.0

1.4

—

104.03

—

Fracture at wrist and hand level

262

2430

1.08

0.58

1.4

128.88

133.70

pmol/l

0.05

255

2361

Malignant neoplasm of nasal cavity and sinuses, excluding all cancers (controls excluding all cancers)

1.73

0.58

1.2

1.3

54.17

54.51

pmol/l

—

Pain in throat and chest

1007

5923

1.04

0.58

1.4

101.15

123.82

pmol/l

1.35

981

5790

Direct fill therapy

109

970

1.13

0.57

1.5

178.61

164.63

pmol/l

0.12

109

949

Falls/tendency to fall

1359

7032

0.97

0.57

1.4

112.17

121.04

pmol/l

0.29

1314

6868

L04AA Selective immunosuppressants

185

2018

0.92

0.57

1.6

1.5

116.44

150.00

pmol/l

1.03

177

1969

Diabetes mellitus in pregnancy

574

3911

0.95

0.57

1.5

1.4

74.78

75.10

pmol/l

0.01

557

3828

Acquired clawhand, clubhand, clawfoot and clubfoot

1.69

0.57

1.8

1.3

179.50

80.97

pmol/l

—

Anorexia (incl.atypical)

625

0.84

0.57

1.2

1.4

47.53

116.80

pmol/l

1.87

607

Intestinal infectious diseases

1059

7946

1.04

0.57

1.4

143.74

122.40

pmol/l

0.57

1014

7753

Benign neoplasm: Sigmoid colon

125

1123

1.12

0.56

1.3

1.5

156.18

205.50

pmol/l

0.51

119

1094

Other disorders of white blood cells

347

1.21

0.56

1.6

1.5

102.10

198.98

pmol/l

1.17

339

Carpal tunnel syndrome

744

6435

1.04

0.56

1.4

155.49

140.67

pmol/l

0.22

728

6283

Macular hole

374

0.80

0.56

1.3

1.5

265.23

299.35

pmol/l

0.07

365

Morphin

1.55

0.55

1.5

148.49

145.23

pmol/l

—

Eclampsia

1.62

0.55

1.2

1.5

57.83

46.12

pmol/l

—

Coxarthrosis, primary, with hip surgery

327

3303

0.94

0.55

1.4

1.5

153.46

196.40

pmol/l

1.27

318

3219

Sleep disorders

215

1986

1.08

0.55

1.4

1.5

85.70

124.69

pmol/l

1.61

207

1932

Pustular psoriasis

417

0.81

0.55

1.2

1.5

112.26

212.37

pmol/l

1.17

411

Behavioural disorders, excluding more controls

122

0.65

0.55

1.1

1.4

41.38

60.85

pmol/l

—

116

Diseases of the musculoskeletal system and connective tissue

736

3534

1.05

0.55

1.5

1.4

132.28

115.28

pmol/l

0.29

721

3444

Mouth breathing

299

2796

1.07

0.54

1.4

93.05

140.83

pmol/l

2.86

290

2719

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

389

3673

1.06

0.54

1.5

1.4

160.18

140.12

pmol/l

0.17

381

3574

Chronic hepatitis, not elsewhere classified

267

1.24

0.54

1.4

1.5

125.85

222.92

pmol/l

0.77

262

Insulin, fast-acting or short human

235

2528

0.93

0.54

1.4

148.72

142.84

pmol/l

0.08

227

2455

Other abnormal products of conception

565

3947

0.95

0.53

1.4

68.48

91.34

pmol/l

1.25

552

3862

Diseases of arteries, arterioles and capillaries (FINNGEN)

172

1312

0.91

0.53

1.4

149.04

148.37

pmol/l

0.01

164

1292

Benign neoplasm: Nasopharynx

1.55

0.53

1.5

1.3

67.67

60.26

pmol/l

—

Asthma and opportunity respiratory infection

316

0.79

0.53

1.7

1.5

92.24

210.47

pmol/l

1.95

309

Disorders of synovium and tendon

648

5585

1.05

0.53

1.4

113.53

133.57

pmol/l

0.81

627

5455

Superficial injury of wrist and hand

185

1703

1.09

0.52

1.4

1.5

132.46

120.72

pmol/l

0.07

180

1655

Voice disturbances

255

2733

0.93

0.52

1.4

213.44

146.81

pmol/l

0.65

245

2661

Varus deformity, not elsewhere classified

0.60

0.52

1.2

1.3

52.83

222.72

pmol/l

—

Malignant neoplasm of other and unspecified parts of tongue, excluding all cancers (controls excluding all cancers)

1.43

0.52

1.6

1.3

76.67

60.49

pmol/l

—

Carcinoma in situ of uteri, other/unspecified

1.42

0.52

1.6

1.4

58.00

53.54

pmol/l

—

Lymphangioma, anys site

1.51

0.52

1.2

1.3

55.00

61.77

pmol/l

—

Wet age-related macular degeneration

867

1.12

0.52

1.4

168.32

274.00

pmol/l

1.71

830

Tinnitus

212

1965

1.08

0.51

1.4

102.47

175.28

pmol/l

2.77

206

1916

Other (seronegative) rheumatoid arthritis, wide

167

1817

0.92

0.51

1.5

1.4

180.86

177.48

pmol/l

0.03

161

1773

Systemic lupus erythematosus, unspecified

306

1.22

0.51

1.4

1.5

145.43

195.62

pmol/l

0.29

299

Chronic sinusitis

496

4723

1.05

0.51

1.3

1.4

114.50

136.04

pmol/l

0.56

485

4620

Diseases of the respiratory system

907

4378

1.04

0.51

1.5

1.4

157.92

122.89

pmol/l

1.05

879

4290

Implicit bacterial Sepsis

240

2050

1.07

0.50

1.6

1.4

258.21

198.62

pmol/l

0.78

232

1995

Artificial joint re-operation

477

0.84

0.50

1.5

92.65

273.62

pmol/l

3.69

466

Open wound of hip and thigh

162

1.30

0.50

1.4

64.60

135.41

pmol/l

0.54

157

Hypotension

744

1.13

0.50

1.3

1.5

184.34

225.68

pmol/l

0.35

717

468

4419

1.05

0.50

1.5

1.4

139.73

124.59

pmol/l

0.22

454

4300

Other malignant neoplasms of skin (=non-melanoma skin cancer)

382

3185

0.95

0.50

1.6

1.4

201.98

193.97

pmol/l

0.07

370

3102

Diabetic retinopathy, excluding more controls

163

1001

0.92

0.49

1.5

1.4

202.13

185.79

pmol/l

0.15

156

968

Hyperparathyroidism

175

1594

1.09

0.49

1.6

1.5

227.08

226.21

pmol/l

0.00

167

1546

Melanoma in situ of lower limb, including hip

1.58

0.49

1.7

1.3

59.43

59.20

pmol/l

—

Impaction of intestines

1.57

0.49

1.0

1.4

105.71

77.08

pmol/l

—

Hernia

971

6813

0.97

0.49

1.5

1.4

160.65

134.54

pmol/l

0.93

950

6648

Use of fingolimod

110

0.63

0.49

1.4

34.83

54.13

pmol/l

—

105

Disorders of choroid and retina

684

5185

0.96

0.49

1.4

154.48

156.86

pmol/l

0.05

662

5058

Concussion

523

4738

0.95

0.49

1.4

114.21

127.66

pmol/l

0.42

503

4628

Sleep apnoea, including avohilmo

1026

6879

0.97

0.48

1.4

124.72

136.89

pmol/l

0.36

996

6725

Malignant neoplasm of tonsil, excluding all cancers (controls excluding all cancers)

1.53

0.48

1.0

1.3

697.71

66.70

pmol/l

—

ILD, hospital admissions 3, with pneumonia sepsis

377

0.82

0.48

1.9

1.5

242.65

253.20

pmol/l

0.04

371

Delirium, not induced by alcohol and other psychoactive substances

463

0.84

0.48

1.9

1.5

247.41

237.35

pmol/l

0.03

449

Extrapyramidal and movement disorders

266

2834

0.94

0.48

1.4

1.5

112.66

180.92

pmol/l

3.29

258

2756

L04AD Calcineurin inhibitors

719

1.13

0.47

1.7

1.5

178.27

167.88

pmol/l

0.09

709

Nonorganic sleeping disorders

192

1781

1.08

0.47

1.4

1.5

82.86

122.45

pmol/l

1.49

184

1735

Flat foot [pes planus] (acquired)

1015

0.89

0.47

1.3

1.4

96.61

179.81

pmol/l

2.14

989

Mental and behavioural disorders due to opioids

222

0.76

0.47

1.7

1.3

74.18

112.35

pmol/l

0.37

217

Other and unspecified dermatitis

554

5307

1.04

0.46

1.4

114.21

141.33

pmol/l

1.18

533

5181

Disorders of vestibular function (Vertigo)

487

4620

1.05

0.46

1.5

1.4

132.97

165.81

pmol/l

1.30

475

4499

Dermatitis

654

6287

1.04

0.46

1.4

115.96

138.69

pmol/l

0.93

631

6131

Hypertrophy of breast

278

2617

1.06

0.46

1.3

1.5

101.95

131.45

pmol/l

0.78

268

2556

Other/unspecified enthesopathies of lower limb, excluding foot

646

1.13

0.46

1.7

1.5

251.16

167.31

pmol/l

0.18

635

Carcinoma in situ of other and unspecified sites

1.43

0.46

1.3

1.5

203.86

66.72

pmol/l

—

Hypertrophy of breast in women and men

278

2618

1.06

0.45

1.3

1.5

101.95

131.43

pmol/l

0.78

268

2557

Viral pneumonia

791

0.88

0.45

1.5

172.06

179.26

pmol/l

0.05

773

Psoriasis vulgaris

124

1357

0.91

0.45

1.5

139.46

166.19

pmol/l

0.24

119

1324

Malignant neoplasm of oropharynx, excluding all cancers (controls excluding all cancers)

1.40

0.45

1.0

1.4

697.71

66.46

pmol/l

—

Rheumatoid arthritis

343

3288

0.95

0.45

1.5

1.4

223.59

154.04

pmol/l

0.80

334

3206

Other retinal disorders

478

4017

0.96

0.45

1.4

181.20

170.25

pmol/l

0.20

459

3914

Schizoaffective disorder

652

0.87

0.45

1.5

109.27

154.00

pmol/l

0.54

643

Fall on and from stairs and steps

225

2106

1.07

0.44

1.4

152.97

160.16

pmol/l

0.10

219

2045

Pacemaker

165

1483

1.08

0.44

1.4

245.00

231.91

pmol/l

0.08

158

1433

Spirochaetal infections, other/unspecified

648

1.13

0.44

1.4

1.5

95.36

189.27

pmol/l

1.94

634

Alcohol use disorder, Swedish definition

318

3118

0.95

0.44

1.5

1.4

167.75

125.76

pmol/l

0.66

308

3040

Mandibular retrognathia AND surgery (BSSRO)

252

0.79

0.44

1.6

1.4

80.48

135.60

pmol/l

0.47

247

Superficial injury of thorax

978

0.90

0.44

1.4

1.5

78.73

171.17

pmol/l

3.58

955

ILD medications: immunosuppressive drugs

661

6578

0.96

0.43

1.5

1.4

137.30

127.47

pmol/l

0.17

639

6419

Lesion of sciatic nerve

241

0.79

0.43

1.8

1.4

125.63

253.59

pmol/l

1.46

236

Amyloidosis, other/unspecified

104

1.35

0.43

1.9

1.5

97.86

389.04

pmol/l

1.20

104

Symptoms and signs involving cognition, perception, emotional state and behaviour

1042

7522

0.97

0.43

1.4

134.76

130.40

pmol/l

0.08

1018

7334

Fibrosarcoma, excluding all cancers (controls excluding all cancers)

1.62

0.43

1.6

1.4

162.40

62.98

pmol/l

—

Other peripheral vertigo

754

1.12

0.43

1.6

1.5

117.05

210.67

pmol/l

1.68

739

Shoulder lesions

874

5179

1.03

0.42

1.5

1.4

132.37

140.17

pmol/l

0.25

854

5060

Behavioural syndromes associated with physiological disturbances and physical factors

357

3395

1.05

0.42

1.3

1.5

73.34

105.29

pmol/l

2.48

347

3296

Congenital malformations of aortic and mitral valves

167

1.26

0.42

1.3

1.4

61.19

136.46

pmol/l

0.62

162

Sphingolipidosis, other/unspecified

0.00

0.42

0.0

1.7

—

739.84

—

Congenital malformations of nose

0.00

0.42

0.0

1.3

—

60.79

—

Congenital myopathies

0.00

0.41

0.0

1.8

—

48.54

—

Asthma-related pneumonia

265

2802

0.94

0.41

1.6

1.4

252.62

157.07

pmol/l

1.07

257

2720

Paralytic strabismus

416

1.16

0.41

1.4

1.5

81.22

223.20

pmol/l

2.57

410

Unspecified organic or symptomatic mental disorder

0.00

0.41

0.0

1.3

—

80.11

—

Injury of blood vessels at hip and thigh level

0.00

0.41

0.0

1.3

—

98.25

—

Benign neoplasm: Other and unspecified parts of mouth

231

1.22

0.41

1.4

1.5

60.75

215.76

pmol/l

1.53

225

Poikiloderma of Civatte

0.00

0.41

0.0

1.2

—

87.35

—

Condition for Implicit Sepsis (Organ dysfunction codes)

800

6004

0.97

0.41

1.5

1.4

169.23

135.51

pmol/l

1.18

770

5857

Insulin, fast-acting

235

2495

0.94

0.41

1.4

148.72

142.83

pmol/l

0.08

227

2424

Isolated patent ductus arteriosus

0.00

0.41

0.0

1.5

—

55.29

—

Disorder of carbohydrate metabolism, other/unspecified

0.00

0.41

0.0

1.4

—

51.39

—

Osteonecrosis

380

0.84

0.41

1.4

1.5

179.06

281.81

pmol/l

0.72

374

Dental pulpitis 3

111

729

1.10

0.41

1.6

1.4

42.28

45.98

pmol/l

0.60

102

686

Squamous cell neoplasms and carcinoma of cervix, excluding all cancers (controls excluding all cancers)

1.35

0.40

1.1

1.3

240.38

57.71

pmol/l

—

Thyrotoxicosis, other and/or unspecified

242

2281

1.06

0.40

1.4

227.70

146.68

pmol/l

0.49

236

2218

Chronic rhinitis, nasopharyngitis and pharyngitis

353

3362

1.05

0.40

1.5

1.4

100.22

137.93

pmol/l

1.35

342

3281

Melanoma in situ of trunk

1.48

0.40

1.2

1.3

67.80

67.68

pmol/l

—

Noninfective disorders of pinna

0.00

0.40

0.0

1.2

—

62.91

—

Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances

287

1.19

0.40

1.4

1.5

60.09

145.31

pmol/l

0.89

281

Osteogenesis imperfecta

0.00

0.40

0.0

1.3

—

58.52

—

Injuries to the neck

201

1884

1.07

0.40

1.4

1.5

92.70

124.32

pmol/l

0.83

193

1834

Fracture of forearm

596

5789

0.96

0.40

1.5

1.4

145.73

149.51

pmol/l

0.07

577

5637

Unknown and unspecified causes of morbidity

560

0.87

0.39

1.4

107.00

181.31

pmol/l

1.02

550

Maxillary retrognathism

137

0.73

0.39

1.1

1.3

63.60

140.66

pmol/l

—

132

Other and unspecified follicular disorders

248

0.80

0.39

1.4

67.95

143.94

pmol/l

0.90

242

Postpartum care and examination

233

1577

0.94

0.39

1.3

1.4

69.44

64.87

pmol/l

0.10

222

1536

Scabies

242

1.20

0.39

1.3

1.4

51.45

117.99

pmol/l

0.87

235

Dental caries 1 and operation codes, only avohilmo

312

1488

1.06

0.38

1.5

1.4

177.50

116.61

pmol/l

0.68

305

1443

Asthma-related pneumonia or sepsis

267

2813

0.95

0.38

1.6

1.4

251.02

157.25

pmol/l

1.06

259

2731

Asthma, hospital admissions 3, pneumonia

267

2813

0.95

0.38

1.6

1.4

251.02

157.25

pmol/l

1.06

259

2731

Melanocytic naevi of trunk

105

962

1.09

0.38

1.5

111.70

150.81

pmol/l

0.46

105

945

Immunodeficiencies

383

1.15

0.37

1.6

1.5

134.00

169.42

pmol/l

0.26

377

Malignant neoplasm of adrenal gland, excluding all cancers (controls excluding all cancers)

1.36

0.37

1.0

1.3

60.60

52.35

pmol/l

—

Other specified disorders of external ear

112

0.71

0.37

1.1

1.4

139.50

227.84

pmol/l

—

112

Finngen Rheumatological endpoints

1154

6746

0.97

0.36

1.5

1.4

123.73

115.23

pmol/l

0.24

1120

6583

Other disorders of amniotic fluid and membranes

210

2205

0.94

0.36

1.5

1.4

71.17

80.07

pmol/l

0.23

203

2148

Diabetes medication

1188

7399

0.98

0.36

1.4

179.62

118.94

pmol/l

2.24

1147

7230

Other and unspecified papulosquamous disorders

1.48

0.36

1.7

1.6

58.83

324.43

pmol/l

—

Bitten or stung by nonvenomous insect and other nonvenomous arthropods

256

0.82

0.36

1.3

1.4

50.00

192.10

pmol/l

1.50

251

Atypical mycobacterium lung infection

0.65

0.36

1.2

1.5

118.20

238.84

pmol/l

—

Myocardial infarction, with ST-elevation

481

0.87

0.36

1.5

155.36

259.67

pmol/l

1.23

467

Diffuse brain injury

179

0.78

0.35

1.5

1.4

67.57

202.98

pmol/l

1.27

179

ILD medications

1371

7355

1.02

0.35

1.4

127.22

120.90

pmol/l

0.19

1336

7167

Chronic thyroiditis

1.41

0.35

1.0

1.4

130.67

325.94

pmol/l

—

Right bundle-branch block

153

1.25

0.35

1.5

1.4

427.26

290.78

pmol/l

0.14

153

Exclusions for E4_PCOS_BROAD

149

1390

1.07

0.35

1.4

1.5

88.68

144.53

pmol/l

1.69

144

1357

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

273

1.18

0.35

1.3

1.5

213.46

247.03

pmol/l

0.10

267

Other disorders of ear

931

6370

0.97

0.35

1.4

122.98

144.89

pmol/l

1.13

903

6223

Personality disorders, excluding more controls

265

2784

0.95

0.34

1.5

114.02

104.60

pmol/l

0.11

258

2713

Other and unspecified tonsillitis

288

2562

0.95

0.34

1.4

1.5

58.45

87.68

pmol/l

2.30

273

2496

Malignant neoplasm of skin

466

3641

0.96

0.34

1.5

1.4

181.35

183.38

pmol/l

0.02

454

3551

Chronic Coagulation defects

237

1.19

0.34

1.2

1.4

133.50

113.35

pmol/l

0.10

231

Psychiatric diseases

1367

6695

1.02

0.34

1.5

1.4

137.00

125.76

pmol/l

0.28

1331

6534

Acute laryngitis and tracheitis

102

925

1.09

0.34

1.6

1.5

63.75

121.15

pmol/l

1.85

902

Arthropod-borne viral fevers and viral haemorrhagic fevers

557

1.11

0.34

1.4

1.5

107.67

187.40

pmol/l

1.14

549

Disorders of ocular muscles, binocular movement, accommodation and refraction

480

4932

0.96

0.33

1.5

1.4

85.59

122.72

pmol/l

2.41

464

4801

Cervical disc disorders

347

3326

1.04

0.33

1.5

1.4

148.05

155.57

pmol/l

0.08

339

3250

Injuries to the hip and thigh

353

3097

1.04

0.33

1.4

128.99

178.28

pmol/l

1.84

335

3015

Mental and behavioural disorders due to sedatives or hypnotics

456

0.88

0.33

1.6

1.5

162.50

183.07

pmol/l

0.07

450

Insulin, intermediate and long-acting

356

3638

0.96

0.33

1.5

183.90

155.56

pmol/l

0.55

344

3536

Type 2 diabetes, wide definition

743

4983

0.97

0.33

1.5

1.4

213.93

138.54

pmol/l

2.89

714

4869

Sacroiliitis, not elsewhere classified

435

1.13

0.33

1.6

1.5

73.20

121.62

pmol/l

0.89

427

Diseases of middle ear and mastoid

627

4978

1.03

0.32

1.5

1.4

99.11

113.87

pmol/l

0.49

596

4842

Other disorders of veins

458

4415

1.04

0.32

1.4

146.78

143.26

pmol/l

0.04

448

4312

Cramp and spasm

316

0.85

0.31

1.3

1.4

58.55

187.17

pmol/l

1.71

309

Coxarthrosis, primary

454

4081

0.96

0.31

1.4

157.55

183.42

pmol/l

0.66

441

3979

Other and unspecified injuries of wrist and hand

267

1.16

0.31

1.8

1.5

62.94

175.28

pmol/l

1.66

260

Glaucoma suspect

295

3081

0.96

0.31

1.4

1.5

197.54

175.75

pmol/l

0.21

284

3005

Non-rheumatic valve diseases

341

2592

0.96

0.31

1.4

130.44

176.08

pmol/l

1.95

332

2529

Fall on same level involving ice and snow

586

5685

1.03

0.31

1.4

159.39

139.04

pmol/l

0.31

565

5540

Gonarthrosis,primary

850

5483

0.97

0.30

1.4

220.49

144.67

pmol/l

1.59

830

5359

Acute sinusitis

622

5633

1.03

0.30

1.4

107.10

115.29

pmol/l

0.23

601

5495

Other congenital malformations of skin

325

1.14

0.29

1.3

1.5

82.58

170.94

pmol/l

0.97

318

Maternal care for known or suspected abnormality of pelvic organs

431

3078

0.96

0.29

1.4

69.28

90.13

pmol/l

1.14

417

3006

Trigger finger

136

1446

0.94

0.29

1.4

90.61

150.43

pmol/l

3.31

131

1412

Mental and behavioural disorders due to alcohol

296

3001

0.96

0.29

1.4

1.5

179.05

119.42

pmol/l

0.68

290

2923

Chronic periodontitis

891

1.08

0.28

1.4

1.5

210.65

163.90

pmol/l

0.53

873

Accidents

1099

5623

0.98

0.28

1.4

109.98

128.35

pmol/l

0.63

1070

5500

Retinal detachments and breaks

258

2471

1.04

0.28

1.4

1.5

138.40

188.78

pmol/l

1.19

253

2412

Vocal cord dysfunction

158

1388

1.06

0.27

1.3

1.5

111.30

110.24

pmol/l

0.02

152

1357

Heart failure, strict

335

2503

0.96

0.27

1.5

251.49

209.29

pmol/l

0.53

326

2434

Conduct disorder

121

0.74

0.27

1.1

1.3

44.56

56.06

pmol/l

—

116

D07AA Corticosteroids, weak (group I)

148

1397

1.06

0.27

1.4

1.5

71.63

125.24

pmol/l

2.50

142

1364

Childhood asthma (age<16), excluding more controls

131

977

1.06

0.27

1.4

45.10

46.81

pmol/l

0.32

124

951

Impacted teeth

176

1556

1.05

0.27

1.4

54.23

71.18

pmol/l

0.94

168

1498

Disorders of sclera, cornea, iris and ciliary body

537

5220

1.03

0.26

1.4

139.64

135.94

pmol/l

0.06

520

5092

Valvular heart disease excluding rheumatic fever

343

2598

0.96

0.26

1.4

130.88

175.92

pmol/l

1.92

334

2535

Polyarthritis, unspecified

262

1.15

0.26

1.6

1.5

212.73

212.03

pmol/l

0.00

257

Aortic aneurysm

522

0.90

0.26

1.4

95.25

243.88

pmol/l

3.34

508

Childhood allergy (age < 16)

113

992

0.94

0.26

1.3

1.4

45.38

46.10

pmol/l

0.07

107

940

Acute and subacute iridocyclitis

167

1586

1.05

0.26

1.4

246.34

155.30

pmol/l

0.83

161

1549

Glomerulonephritis

577

1.09

0.26

1.5

152.89

201.90

pmol/l

0.56

568

Adverse effects, not elsewhere classified

213

2036

1.05

0.26

1.3

1.4

91.22

127.62

pmol/l

1.29

207

1984

Central retinal artery occlusion

0.69

0.26

1.2

1.5

178.00

333.88

pmol/l

—

Embolic stroke with flimmer

0.69

0.26

1.4

1.5

106.00

362.08

pmol/l

—

Anomalies of dental arch relationship, including avohilmo

176

1661

0.95

0.26

1.5

86.62

124.62

pmol/l

0.96

168

1616

Supervision of high-risk pregnancy

372

2173

1.04

0.26

1.4

73.77

82.59

pmol/l

0.25

365

2124

Postprocedural disorders of nervous system

790

1.08

0.26

1.4

52.81

128.01

pmol/l

2.46

775

Disorders of parathyroid gland

198

1866

1.05

0.26

1.6

1.4

211.05

218.29

pmol/l

0.04

188

1811

Syncope and collapse

366

3135

1.03

0.25

1.4

155.91

146.99

pmol/l

0.12

351

3048

Malignant neoplasm of head and neck

309

0.87

0.25

1.4

1.5

249.33

287.10

pmol/l

0.11

303

False labour

553

3380

1.03

0.25

1.4

60.35

78.72

pmol/l

1.75

534

3302

Childhood asthma (age<16)

131

981

1.06

0.25

1.4

45.10

46.81

pmol/l

0.32

124

955

Erythema multiforme

179

1.18

0.25

1.3

1.4

284.52

209.04

pmol/l

0.19

174

Diabetes, varying definitions

1200

7300

0.98

0.25

1.4

179.67

117.65

pmol/l

2.33

1160

7133

Pure hypercholesterolaemia

642

4200

1.03

0.25

1.5

1.4

230.35

152.79

pmol/l

2.19

612

4113

Impingement syndrome of shoulder

227

2177

1.04

0.24

1.7

1.4

91.98

150.38

pmol/l

4.17

222

2130

Graves ophthalmopathy

255

0.86

0.24

1.1

1.4

75.05

213.39

pmol/l

1.34

250

Disorders of lacrimal system and orbit in diseases classified elsewhere

255

0.86

0.24

1.1

1.4

75.05

220.58

pmol/l

1.43

249

Ganglion

245

2549

0.96

0.24

1.4

125.64

125.27

pmol/l

0.00

239

2481

Cervicobrachial syndrome

252

2423

1.04

0.24

1.4

111.55

146.63

pmol/l

0.77

247

2364

Injuries to the knee and lower leg

1408

7925

1.02

0.24

1.4

132.52

124.25

pmol/l

0.24

1355

7736

Asthma, hospital admissions , main diagnosis only

947

8314

1.02

0.24

1.5

1.4

114.29

127.53

pmol/l

0.42

925

8094

Disorders of refraction and accommodation

250

2588

0.96

0.24

1.5

1.4

78.77

118.77

pmol/l

3.01

240

2517

Anisometropia and aniseikonia

233

0.86

0.24

1.6

1.4

62.30

208.73

pmol/l

1.40

226

Nonsuppurative otitis media

206

1705

1.04

0.23

1.7

1.5

78.63

113.79

pmol/l

1.41

196

1653

Papulosquamous disorders

346

3573

0.97

0.23

1.4

125.35

149.78

pmol/l

0.55

338

3477

All-cause Heart Failure

330

2458

0.97

0.23

1.5

1.4

253.90

209.95

pmol/l

0.55

321

2390

Other aneurysm

199

1.16

0.23

1.5

110.78

288.26

pmol/l

1.28

194

Melanocytic naevi of ear and external auricular canal

1.29

0.23

1.2

79.80

49.34

pmol/l

—

Atrial septal defect

245

1.14

0.23

1.5

1.3

86.91

126.85

pmol/l

0.40

239

Atopic dermatitis, strict definition with reimbursement

346

3461

0.97

0.23

1.4

1.5

69.25

104.59

pmol/l

2.60

336

3369

Carcinoma in situ, bladder

1.28

0.23

1.4

83.60

69.11

pmol/l

—

Pervasive developmental disorders excl. Autism + Asperger

1.28

0.23

1.4

1.3

310.80

41.74

pmol/l

—

Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

274

0.87

0.23

1.1

1.5

57.29

99.98

pmol/l

0.55

266

Sequelae of injuries of upper limb

679

1.08

0.22

1.6

1.5

112.22

181.62

pmol/l

1.10

664

Other retinal artery occlusion

1.25

0.22

1.9

1.5

200.18

433.70

pmol/l

0.58

Cardiomyopathy, Hypertrophic obstructive

0.76

0.22

1.1

1.4

119.00

308.79

pmol/l

—

Small cell lung cancer, excluding all cancers (controls excluding all cancers)

1.25

0.22

1.0

1.4

306.44

69.88

pmol/l

—

Graves ophthalmopathy, strict

210

0.85

0.22

1.2

1.4

81.83

237.07

pmol/l

1.19

205

Gestational diabetes (for exclusion)

642

4645

0.98

0.22

1.4

66.06

79.01

pmol/l

1.06

622

4536

Other disorders of adrenal gland

343

1.11

0.22

1.4

73.05

204.49

pmol/l

1.89

336

Coxarthrosis

428

2984

0.97

0.22

1.4

148.31

164.10

pmol/l

0.35

419

2911

Erythema ab igne [dermatitis ab igne]

0.00

0.22

0.0

1.4

—

70.64

—

Pemphigus foliaceus

0.00

0.22

0.0

1.2

—

82.50

—

Oral lichen ruber planus wide, hypothyreosis or thyroxin

555

1.08

0.22

1.5

82.97

241.33

pmol/l

3.82

542

Meniscus derangement

548

3841

0.98

0.22

1.4

165.45

144.87

pmol/l

0.30

531

3752

Squamous cell neoplasms and carcinoma of rectum

0.00

0.22

0.0

1.8

—

93.30

—

Edwards' syndrome and Patau's syndrome

0.00

0.22

0.0

1.5

—

54.64

—

Colorectal squamous cell carcinoma

0.00

0.22

0.0

1.8

—

93.30

—

Profound mental retardation

0.00

0.21

0.0

1.5

—

49.56

—

Yaws

0.00

0.21

0.0

1.7

—

48.18

—

Benign neoplasm: Urethra

0.00

0.21

0.0

1.5

—

58.80

—

Epidermolysis bullosa

0.00

0.21

0.0

1.4

—

51.78

—

Tracheo-bronchomalasia

1.20

0.21

1.0

1.5

384.20

130.95

pmol/l

—

Postinflammatory hyperpigmentation

0.00

0.21

0.0

1.1

—

70.00

—

Calcinosis cutis

0.00

0.21

0.0

1.2

—

79.64

—

Nonadministration of surgical and medical care

0.00

0.21

0.0

1.3

—

57.82

—

Specific development disorders of scholastic skills

249

0.87

0.21

1.8

1.4

51.39

51.71

pmol/l

0.02

238

Dengue fever [classical dengue]

0.00

0.21

0.0

1.5

—

49.26

—

Intentional self-harm by smoke, fire and flames

0.00

0.21

0.0

1.4

—

49.50

—

Traumatic amputation of ankle and foot

0.00

0.21

0.0

1.3

—

59.94

—

Other infectious diseases

449

1.09

0.21

1.7

1.5

311.13

195.32

pmol/l

0.25

442

Benign neoplasm: Ciliary body

0.00

0.21

0.0

1.1

—

66.64

—

Pediculosis and phthiriasis

0.00

0.21

0.0

1.4

—

66.64

—

Pneumoconiosis due to asbestos and other mineral fibres

0.00

0.21

0.0

1.3

—

96.36

—

Acute disseminated encephalitis/encephalomyelitis

0.00

0.21

0.0

1.3

—

65.05

—

Other and unspecified disorders of globe

0.00

0.21

0.0

1.1

—

916.95

—

Asthma, hospital admission 2, infections

589

5664

1.02

0.21

1.5

1.4

156.56

130.17

pmol/l

0.52

572

5509

Asthma-related infections

589

5664

1.02

0.21

1.5

1.4

156.56

130.17

pmol/l

0.52

572

5509

Exposure to uncontrolled fire, not in building or structure

0.00

0.21

0.0

1.3

—

61.50

—

Pityriasis rubra pilaris

0.00

0.21

0.0

1.4

—

55.97

—

Allergic rhinitis

345

3519

0.97

0.21

1.4

1.5

92.20

106.12

pmol/l

0.39

335

3429

Congenital malformations of larynx

0.00

0.21

0.0

1.2

—

73.50

—

Chronic lower respiratory diseases

1446

7706

1.02

0.21

1.5

1.4

143.19

120.58

pmol/l

0.68

1413

7503

Asymptomatic human immunodeficiency virus [HIV] infection status

0.00

0.21

0.0

1.4

—

46.67

—

Hyperprolactinaemia

377

0.90

0.21

1.4

47.95

114.75

pmol/l

1.42

371

Assault by drugs, medicaments and biological substances

0.00

0.21

0.0

1.5

—

55.35

—

Sunburn

0.00

0.21

0.0

1.2

—

62.85

—

Exposure to controlled fire, not in building or structure

0.00

0.21

0.0

1.3

—

75.49

—

Disturbances of skin sensation

311

3016

1.03

0.21

1.4

1.5

103.15

120.94

pmol/l

0.36

305

2940

Drug-induced Cushing's syndrome

0.00

0.20

0.0

1.2

—

61.40

—

Mental disorders, not otherwise specified

821

0.94

0.20

1.4

1.5

71.83

135.76

pmol/l

1.48

802

Other protozoal intestinal diseases

123

0.81

0.20

1.2

1.5

44.90

196.85

pmol/l

—

118

Chronic postrheumatic arthropathy [Jaccoud]

0.00

0.20

0.0

1.2

—

797.10

—

Kidney diseases associated to Fabry's disease

0.00

0.20

0.0

1.7

—

789.11

—

Disorders of glossopharyngeal nerve

0.00

0.20

0.0

1.1

—

79.26

—

Melanoma in situ of scalp and neck

0.00

0.20

0.0

1.5

—

90.93

—

Relapsing fevers

0.00

0.20

0.0

1.1

—

68.93

—

Spinal stenosis

403

3243

0.97

0.20

1.4

191.84

177.51

pmol/l

0.13

388

3160

Fetus and newborn affected by other complications of labour and delivery

0.00

0.20

0.0

1.4

—

43.57

—

Other mycoses, not elsewhere classified/unspecified

0.00

0.20

0.0

1.3

—

79.24

—

Injury of blood vessels at neck level

0.00

0.20

0.0

1.6

—

108.36

—

Asthma/COPD (KELA code 203)

1110

7699

1.02

0.20

1.5

1.4

129.95

120.65

pmol/l

0.28

1082

7496

Acute upper respiratory infections of multiple and unspecified sites

866

6373

1.02

0.20

1.5

1.4

110.89

121.23

pmol/l

0.32

836

6216

Postpartum hemorraghe, all women as controls

429

4166

1.03

0.20

1.4

55.22

87.73

pmol/l

5.11

418

4065

Other and unspecified erythematous conditions

239

0.88

0.19

1.3

1.5

66.14

262.74

pmol/l

2.03

234

Amblyopia ex anopsia

281

0.89

0.19

1.4

65.52

193.15

pmol/l

1.37

272

Villonodular synovitis (pigmented)

1.18

0.19

1.3

1.4

63.17

278.77

pmol/l

—

Intentional self-harm by sharp object

186

0.86

0.19

1.3

55.69

65.90

pmol/l

0.48

178

Basal cell carcinoma, including avohilmo

419

3382

0.97

0.19

1.6

1.4

191.94

189.49

pmol/l

0.02

405

3297

Unspecified fall

414

4006

1.03

0.19

1.4

1.5

143.60

151.69

pmol/l

0.11

402

3889

Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

165

1.15

0.19

1.3

1.4

306.95

59.61

pmol/l

0.50

160

Other sexually transmitted chlamydial diseases

598

1.07

0.19

1.4

44.98

51.35

pmol/l

1.04

579

Presence of other functional implants

478

3307

1.02

0.19

1.4

168.06

178.99

pmol/l

0.21

460

3228

Benign neoplasm of eye and adnexa

766

0.94

0.18

1.6

1.5

95.09

210.35

pmol/l

3.02

746

Contact with and exposure to communicable diseases

354

3618

0.97

0.18

1.5

56.30

88.72

pmol/l

4.31

340

3519

Other erythematous conditions

269

0.89

0.18

1.3

1.5

72.21

251.99

pmol/l

2.07

264

Retinal detachment with retinal break

714

0.94

0.18

1.4

1.5

189.33

218.02

pmol/l

0.14

698

Benign neoplasm: Oesophagus

1.21

0.18

1.6

1.4

65.83

58.74

pmol/l

—

Lumbar disc prolapse

702

5477

1.02

0.18

1.4

119.78

134.75

pmol/l

0.55

683

5348

Ehlers-Danlos syndrome

119

1.18

0.18

1.5

1.4

52.64

68.70

pmol/l

0.77

114

Sleep disorders (combined)

1097

7292

0.99

0.18

1.4

122.85

133.52

pmol/l

0.33

1064

7120

Glaucoma

481

4131

1.02

0.18

1.4

222.38

170.82

pmol/l

0.90

463

4024

Diseases of inner ear

537

5151

1.02

0.17

1.5

1.4

128.21

160.09

pmol/l

1.43

523

5020

Other disorders of electrolyte and fluid balance, not elsewhere classified

1.15

0.17

1.7

1.5

275.86

261.19

pmol/l

—

Conjunctivitis (acute, non atopic)

275

2663

1.03

0.17

1.5

1.4

103.15

134.10

pmol/l

0.80

269

2589

Aphakia

1.15

0.17

1.1

1.4

70.43

149.30

pmol/l

—

Mental and behavioural disorders due to psychoactive substance use

408

3939

0.98

0.17

1.5

1.4

158.19

117.88

pmol/l

0.60

400

3837

Atopic dermatitis, strict definition

332

3338

0.97

0.17

1.4

1.5

68.97

99.51

pmol/l

1.97

323

3244

Varicella [chickenpox]

195

1.13

0.17

1.2

1.4

70.86

113.52

pmol/l

0.35

188

Abnormal findings on antenatal screening of mother

116

1213

0.95

0.17

1.3

1.4

46.07

57.96

pmol/l

1.82

111

1175

Idiopathic pulmonary fibrosis

268

0.89

0.17

2.0

1.5

156.71

324.98

pmol/l

1.62

263

Degeneration of macula and posterior pole

336

2700

1.03

0.17

1.4

1.5

188.53

211.50

pmol/l

0.40

318

2632

Other disorders of eye and adnexa

136

1305

1.04

0.17

1.4

97.84

149.21

pmol/l

1.31

129

1272

Acute and transient psychotic disorders

967

0.95

0.16

1.3

1.5

101.19

157.92

pmol/l

1.24

948

Spondylopathies

821

5065

0.98

0.16

1.4

144.37

141.95

pmol/l

0.04

799

4944

Infections of genitourinary tract in pregnancy

146

1405

1.04

0.16

1.5

122.30

142.09

pmol/l

0.16

140

1374

Osteoporosis

243

2250

1.03

0.16

1.4

1.5

176.98

221.87

pmol/l

1.12

232

2189

Superficial injury of lower leg

233

2262

1.03

0.16

1.4

1.5

218.01

136.61

pmol/l

0.58

221

2199

Other systemic involvement of connective tissue (FG)

309

2993

1.03

0.16

1.5

1.4

106.92

153.02

pmol/l

2.69

303

2914

Other respiratory diseases principally affecting the interstitium

894

0.95

0.16

1.7

1.5

169.38

217.28

pmol/l

0.53

868

Pregnancy examination and test

285

1732

1.03

0.16

1.3

1.4

53.29

68.74

pmol/l

1.51

277

1687

Disorders of vitreous body and globe

477

4560

1.02

0.16

1.5

1.4

143.28

172.19

pmol/l

0.79

466

4446

Other disorders of patella

208

2017

1.03

0.16

1.4

127.74

124.25

pmol/l

0.04

202

1962

Diabetes mellitus

1217

7351

0.99

0.16

1.4

178.19

117.10

pmol/l

2.32

1177

7182

Pediculosis, acariasis and other infestations

312

1.09

0.15

1.4

1.3

51.15

171.61

pmol/l

1.55

304

Migraine with aura and triptan purchases

208

2018

1.03

0.15

1.4

1.5

73.76

106.58

pmol/l

1.55

200

1973

Conotruncal defects

0.76

0.15

1.0

1.3

52.33

194.68

pmol/l

—

Thyrotoxicosis with toxic multinodular goitre

565

0.94

0.15

1.4

1.5

98.64

244.22

pmol/l

3.18

552

Other facial nerve disorders

224

0.89

0.15

1.4

49.00

175.34

pmol/l

1.67

219

TMD related operations

175

1694

1.03

0.15

1.5

88.97

138.02

pmol/l

1.36

167

1654

Other neurotic disorders

338

0.92

0.15

1.4

1.5

114.58

213.24

pmol/l

0.89

331

ILD, hospital admissions 1, main diag only

667

0.94

0.15

1.7

1.5

173.76

240.39

pmol/l

0.60

649

Use of interferon beta-1a

265

0.90

0.15

1.5

1.4

69.20

103.95

pmol/l

0.39

259

Benign neoplasm of mouth and pharynx

791

1.05

0.14

1.6

1.5

100.64

196.13

pmol/l

2.02

774

Other hammer toe(s) (acquired)

189

1826

0.97

0.14

1.4

1.5

107.60

197.62

pmol/l

5.53

183

1778

Hyperkinetic disorders (excl. ADHD)

0.80

0.14

1.4

1.3

48.43

46.93

pmol/l

—

Other renal tubulo-interstitial diseases

223

0.89

0.14

2.1

1.4

277.19

145.97

pmol/l

0.47

217

Pregnancy with abortive outcome

1209

6395

0.99

0.14

1.5

1.4

147.82

129.43

pmol/l

0.50

1169

6230

Viral conjunctivitis

198

1.11

0.14

1.2

1.4

100.18

192.05

pmol/l

0.51

193

Benign neoplasm: Skin of trunk

314

1.08

0.14

1.7

1.4

137.61

212.99

pmol/l

0.57

308

Conductive and sensorineural hearing loss

735

5163

0.99

0.14

1.5

1.4

134.00

159.86

pmol/l

1.19

713

5036

Herpesviral keratitis and keratoconjunctivitis

295

0.91

0.14

1.1

1.4

112.68

224.87

pmol/l

0.97

290

Hypermetropia

511

0.94

0.14

1.3

1.5

89.49

196.66

pmol/l

1.77

499

266

2563

0.98

0.14

1.5

195.77

215.26

pmol/l

0.25

255

2491

Other and unspecified effects of external causes

278

2716

1.02

0.14

1.4

89.06

121.38

pmol/l

1.47

270

2646

Symptoms and signs involving the nervous and musculoskeletal systems

553

5615

0.98

0.13

1.4

99.72

142.08

pmol/l

2.82

530

5478

Unspecified privation

735

1.05

0.13

1.3

1.5

147.00

179.73

pmol/l

0.29

720

Benign neoplasm: Choroid

413

1.07

0.13

1.8

1.5

84.67

228.00

pmol/l

2.28

403

Other extrapyramidal and movement disorders in other diseases

185

1800

1.03

0.13

1.3

1.4

90.47

173.65

pmol/l

5.14

179

1754

Unspecified lump in breast

225

2196

1.03

0.12

1.4

1.5

150.75

163.55

pmol/l

0.14

220

2141

Placental disorders

127

0.86

0.12

1.1

1.3

47.00

151.07

pmol/l

0.66

122

Other disorders of eyelid

409

3882

1.02

0.12

1.4

115.26

186.35

pmol/l

4.34

399

3783

Motorcycle rider injured in noncollision transport accidents

123

1.14

0.12

1.0

1.3

136.57

152.87

pmol/l

0.05

117

Foreign body entering into or through eye or natural orifice

365

0.93

0.12

1.3

1.5

102.21

181.95

pmol/l

0.76

357

Papilloedema, unspecified

179

0.89

0.12

1.8

1.4

184.87

128.66

pmol/l

0.17

174

Tuberculosis, IBD comorbidity

365

1.07

0.12

1.3

1.5

131.50

237.10

pmol/l

1.16

357

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

297

1.08

0.12

1.6

1.4

71.04

121.42

pmol/l

0.62

286

Clefts and syndromes for tooth agenesis exclusion, including avohilmo

220

0.91

0.12

1.6

1.4

58.46

109.49

pmol/l

0.53

214

Chromosomal abnormalities, not elsewhere classified

142

1.13

0.12

1.3

57.50

59.40

pmol/l

0.06

137

Preterm labour and delivery

413

4199

0.98

0.12

1.4

89.98

125.36

pmol/l

2.51

401

4105

Other symptoms and signs involving the nervous and musculoskeletal systems

416

4230

0.98

0.12

1.4

78.58

137.60

pmol/l

8.54

397

4126

Tuberculosis, wide

375

1.07

0.12

1.3

1.5

129.69

256.20

pmol/l

1.46

366

Cleft lip, lip and palate or palate

137

0.87

0.12

1.7

1.3

61.00

53.63

pmol/l

0.29

132

Vitamin B12 deficiency anaemia

660

0.95

0.11

1.4

112.13

213.76

pmol/l

2.00

640

Ulcerative proctitis

476

0.94

0.11

1.3

1.5

71.68

141.71

pmol/l

1.03

465

Neuralgia and neuritis, unspecified

435

0.94

0.11

1.5

72.88

163.39

pmol/l

2.16

428

Other assisted single delivery

289

1.08

0.11

1.6

1.5

52.71

59.59

pmol/l

0.55

282

Embedded and impacted teeth

259

2157

1.02

0.11

1.5

54.21

84.71

pmol/l

2.29

249

2087

Basal cell carcinoma

408

3302

0.98

0.11

1.6

1.4

192.60

192.41

pmol/l

0.00

396

3218

Benign neoplasm: Other/unspecified site

1.17

0.11

2.2

1.4

54.50

61.36

pmol/l

—

Crystal arthropathies, rheuma endpoint

1.17

0.11

1.6

1.4

216.10

407.65

pmol/l

—

Superficial injury of abdomen, lower back and pelvis

111

1146

0.97

0.11

1.3

1.5

61.32

152.23

pmol/l

4.68

104

1116

Conjunctivitis

955

8239

1.01

0.10

1.4

99.78

127.18

pmol/l

1.86

936

8020

Primary coxarthrosis, bilateral

201

1965

1.02

0.10

1.4

1.5

163.80

227.09

pmol/l

1.29

193

1906

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

401

3942

1.02

0.10

1.5

1.4

99.59

106.60

pmol/l

0.16

387

3829

Hereditary corneal dystrophies

231

1.08

0.10

1.1

1.5

76.61

299.61

pmol/l

2.34

226

Other cataract

342

2693

0.98

0.10

1.5

176.11

171.08

pmol/l

0.05

328

2633

Bronchitis

1224

8094

0.99

0.10

1.5

1.4

130.70

124.88

pmol/l

0.13

1181

7897

Autoimmune diseases excluding thyroid diseases

1154

6461

0.99

0.10

1.4

142.38

117.67

pmol/l

0.81

1122

6296

Other (not insulin) diabetes medications

1102

6702

0.99

0.10

1.4

180.95

125.96

pmol/l

1.75

1065

6554

Skin changes due to chronic exposure to nonionizing radiation

246

2373

0.98

0.10

1.5

197.02

224.34

pmol/l

0.36

237

2309

Injuries to the ankle and foot

758

6977

0.99

0.10

1.5

1.4

111.90

113.44

pmol/l

0.04

733

6803

Coxarthrosis [arthrosis of hip](FG)

472

3461

0.99

0.10

1.4

146.75

164.03

pmol/l

0.44

460

3382

Fracture of foot, except ankle

220

2155

1.02

0.10

1.4

108.11

132.59

pmol/l

0.70

214

2098

Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis

218

0.92

0.10

1.5

1.4

61.50

127.70

pmol/l

0.72

213

Polypectomy (DHB20)

290

1.07

0.10

1.3

1.4

77.42

200.91

pmol/l

1.40

285

Other bursopathies

105

1018

1.03

0.10

1.5

122.98

169.71

pmol/l

0.79

105

999

Supplementary factors related to causes of morbidity and mortality classified elsewhere

247

2424

1.02

0.10

1.4

151.54

135.07

pmol/l

0.22

241

2357

Autoimmune diseases excluding thyroid diseases, strict definition

1118

6281

0.99

0.09

1.4

145.83

118.11

pmol/l

0.91

1086

6120

Alcohol use disorder, ICD-based

223

2274

0.98

0.09

1.4

1.5

152.62

129.34

pmol/l

0.23

218

2214

Injury of nerves at wrist and hand level

203

1.09

0.09

1.2

1.4

114.23

148.74

pmol/l

0.17

198

Intracranial injury

484

4735

0.99

0.09

1.4

1.5

116.05

139.22

pmol/l

0.91

461

4607

Biguanides

1052

6535

0.99

0.09

1.4

165.03

129.39

pmol/l

1.82

1016

6388

Cerebral cysts

409

1.05

0.09

1.4

1.5

70.93

124.74

pmol/l

1.03

400

Fracture of femur

151

1411

0.98

0.09

1.4

175.22

225.73

pmol/l

0.76

141

1369

Artificial joint operation, meniscal resection

864

5696

1.01

0.09

1.4

192.03

145.31

pmol/l

0.85

840

5560

Strabismus

252

2473

1.02

0.09

1.4

91.40

130.67

pmol/l

1.14

245

2403

Injuries to the abdomen, lower back, lumbar spine and pelvis

313

3062

1.02

0.09

1.4

121.03

160.47

pmol/l

1.19

303

2967

Abnormalities of forces of labour

159

1625

0.98

0.09

1.3

1.4

110.60

93.14

pmol/l

0.20

154

1589

Hypertension, Pulmonary Arterial

1.05

0.08

2.2

1.4

168.17

150.69

pmol/l

—

Type of accident

230

2260

1.02

0.08

1.4

154.50

135.50

pmol/l

0.25

224

2197

Assault by sharp object

1.05

0.08

1.3

1.5

79.83

72.87

pmol/l

—

Hypertensive heart and/or renal disease

132

1048

0.98

0.08

1.4

1.5

476.41

203.96

pmol/l

1.37

126

1027

Open wound of head

338

3375

0.99

0.08

1.5

146.04

156.71

pmol/l

0.12

321

3275

Common variable immunodeficiency

0.83

0.08

1.4

1.6

83.00

70.41

pmol/l

—

Other congenital malformations, not elsewhere classified

0.78

0.08

1.4

1.2

59.60

64.02

pmol/l

—

Dizziness and giddiness

793

6490

0.99

0.08

1.5

1.4

136.00

137.32

pmol/l

0.02

772

6335

Disorders of orbit

401

1.05

0.08

1.5

97.33

219.17

pmol/l

1.62

392

Non-selective monoamine reuptake inhibitors

417

4092

0.99

0.08

1.5

1.4

176.47

153.62

pmol/l

0.27

408

4004

Melanocytic naevi of lip

1.05

0.08

1.3

49.00

57.52

pmol/l

—

Nummular dermatitis

470

0.96

0.08

1.5

174.31

210.47

pmol/l

0.13

462

Chronic conjunctivitis

256

0.94

0.08

1.5

1.4

99.42

223.25

pmol/l

0.97

251

Oral leukoplakia and related diseases

362

1.05

0.07

1.6

1.5

122.21

256.41

pmol/l

1.58

357

Cleft palate

1.13

0.07

1.6

1.4

62.82

51.60

pmol/l

0.44

Hyperlipidaemia, other/unspecified

243

2264

1.02

0.07

1.4

177.54

183.90

pmol/l

0.07

230

2215

Congenital malformations of the nervous system

174

0.92

0.07

1.7

1.3

45.38

65.25

pmol/l

1.94

169

Interstitial lung disease

743

0.97

0.07

1.6

1.5

168.22

233.86

pmol/l

0.68

720

Interstitial lung disease endpoints

743

0.97

0.07

1.6

1.5

168.22

233.86

pmol/l

0.68

720

Sensorineural hearing loss

680

4800

0.99

0.07

1.5

1.4

135.08

165.44

pmol/l

1.39

662

4681

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

348

3399

1.01

0.07

1.5

1.4

82.09

94.39

pmol/l

0.32

339

3310

Other enthesopathies

346

3418

1.01

0.07

1.5

1.4

100.66

141.62

pmol/l

3.16

339

3338

Other interstitial pulmonary diseases

742

0.97

0.07

1.6

1.5

168.22

234.05

pmol/l

0.68

719

Toxic effect of ethanol

245

1.06

0.07

1.3

1.4

61.54

141.97

pmol/l

0.96

238

Hallux valgus (acquired)

471

3375

1.01

0.07

1.4

141.95

153.42

pmol/l

0.26

454

3295

Transport accidents

499

4382

1.01

0.07

1.5

1.4

82.30

123.46

pmol/l

3.08

475

4280

Perioral dermatitis

234

0.94

0.06

1.6

1.4

60.31

198.16

pmol/l

1.24

229

142

0.91

0.06

1.5

1.4

45.31

51.16

pmol/l

0.23

137

Thyrotoxicosis

291

2944

0.99

0.06

1.4

205.14

143.33

pmol/l

0.44

285

2862

Primary open-angle glaucoma, strict

178

1804

0.98

0.06

1.5

241.26

221.11

pmol/l

0.17

168

1752

Pollen allergy

189

1897

0.99

0.06

1.4

66.67

102.93

pmol/l

1.50

183

1847

Obstructed labour due to maternal pelvic abnormality

235

2321

1.01

0.06

1.4

102.94

140.94

pmol/l

1.27

227

2267

Exposure to other and unspecified animate mechanical forces

243

0.95

0.05

1.5

1.4

58.17

109.99

pmol/l

0.62

236

Anomalies of pupillary function

188

1.07

0.05

1.7

1.4

99.40

166.51

pmol/l

0.40

183

Other and unspecified disorders of vitreous body

391

3923

0.99

0.05

1.5

1.4

147.61

178.44

pmol/l

0.69

386

3828

Primary gonarthrosis, bilateral

448

3887

1.01

0.05

1.4

221.50

168.63

pmol/l

0.66

434

3796

ILD, hospital admission 2, with pulmonary infections

445

0.97

0.05

1.7

1.5

208.05

266.13

pmol/l

0.31

434

Thoracic aortic aneurysm

376

1.04

0.05

1.4

1.5

100.38

272.48

pmol/l

2.64

370

Type 2 diabetes, definitions combined, including avohilmo

1122

6610

1.00

0.05

1.4

176.82

123.60

pmol/l

1.68

1085

6463

Vasomotor and allergic rhinitis

434

4308

0.99

0.04

1.5

1.4

116.85

119.13

pmol/l

0.04

420

4198

Tobacco use

347

1.04

0.04

1.5

1.4

159.26

166.26

pmol/l

0.03

340

Diaphragmatic hernia

318

3152

1.01

0.04

1.5

1.4

172.80

171.39

pmol/l

0.02

312

3066

Bipolar affective disorders

190

1922

0.99

0.04

1.3

1.5

95.86

114.39

pmol/l

0.50

182

1878

Contact with machinery

209

1.05

0.04

1.5

1.4

63.86

224.53

pmol/l

1.30

204

Allergic colitis

130

1.08

0.04

1.4

46.65

136.04

pmol/l

0.56

125

Type 2 diabetes, definitions combined

1105

6565

1.00

0.04

1.4

176.58

125.17

pmol/l

1.58

1069

6417

Caries in Clefts patients

1.10

0.04

1.8

1.3

63.90

52.63

pmol/l

—

Other CVD (FINNGEN)

578

1.02

0.04

1.3

1.5

168.77

170.51

pmol/l

0.01

566

Implicit Sepsis

644

4978

1.01

0.04

1.5

1.4

186.03

146.32

pmol/l

1.14

616

4859

Other demyelinating diseases of the central nervous system

372

0.97

0.04

1.2

1.5

59.21

115.60

pmol/l

1.03

366

Viral pneumonia (known virus, not influenza)

111

1.08

0.04

1.3

1.4

119.92

305.71

pmol/l

0.71

111

Tuberculosis

281

0.96

0.04

1.3

1.5

129.37

284.54

pmol/l

1.51

276

Blepharochalasis

274

2762

0.99

0.03

1.4

117.91

202.44

pmol/l

3.42

267

2695

ILD, hospital admissions

734

0.98

0.03

1.6

1.5

168.22

234.58

pmol/l

0.69

711

Suggestive for eosinophilic asthma

617

1.02

0.03

1.6

1.5

86.35

186.47

pmol/l

2.31

607

Disorders of lipoprotein metabolism and other lipidaemias

750

4734

1.00

0.03

1.5

1.4

210.90

143.78

pmol/l

2.19

717

4641

Soft tissue disorders related to use, overuse and pressure

252

2500

1.01

0.03

1.5

1.4

93.92

153.51

pmol/l

3.63

245

2439

Juvenile osteochondrosis

250

1.04

0.03

1.4

60.42

129.62

pmol/l

0.79

242

Injuries to the thorax

289

2910

0.99

0.03

1.5

116.94

166.99

pmol/l

2.39

277

2821

Otitis media, unspecified

779

1.02

0.03

1.4

51.49

118.50

pmol/l

2.36

757

Diseases of the eye and adnexa

1045

5216

1.00

0.03

1.5

1.4

109.09

115.84

pmol/l

0.18

1023

5088

Keratitis

309

3110

0.99

0.03

1.4

92.59

135.59

pmol/l

2.11

304

3020

Deviated nasal septum

193

1912

1.01

0.03

1.4

126.72

152.28

pmol/l

0.33

186

1871

Other strabismus

212

2131

0.99

0.03

1.5

1.4

92.39

125.39

pmol/l

0.72

205

2075

Spontaneous abortion

836

5666

1.00

0.03

1.4

132.50

121.75

pmol/l

0.23

817

5531

Congenital malformations of great arteries

106

0.93

0.03

1.2

1.3

104.50

69.75

pmol/l

—

101

Synovial cyst of popliteal space [Baker]

611

0.98

0.02

1.4

1.5

113.70

184.45

pmol/l

1.48

598

Disorders of vitreous body

459

4472

1.00

0.02

1.5

1.4

143.03

171.76

pmol/l

0.75

449

4360

Preparation and fitting of bite rail to mouth

135

1337

1.01

0.02

1.4

1.5

91.72

138.05

pmol/l

0.92

129

1305

Persons with potential health hazards related to communicable diseases

424

4222

1.00

0.02

1.4

78.07

95.89

pmol/l

1.17

407

4108

Mental and behavioural disorders due to alcohol, excluding acute intoxication

242

2431

0.99

0.02

1.4

1.5

163.44

127.49

pmol/l

0.40

236

2369

Open wound of forearm

509

0.98

0.02

1.5

126.42

178.65

pmol/l

0.54

494

Other congenital malformations of ear

117

0.94

0.01

1.5

1.3

39.36

52.84

pmol/l

1.49

111

Erysipelas

386

3508

1.00

0.01

1.5

1.4

191.67

146.56

pmol/l

0.63

375

3423

Other/unspecified synovitis and tenosynovitis

109

1100

0.99

0.01

1.5

1.4

121.09

153.75

pmol/l

0.49

103

1075

Migraine with aura

328

3267

1.00

0.01

1.4

69.82

116.93

pmol/l

5.00

318

3189

Fracture of shoulder and upper arm

285

2860

1.00

0.01

1.5

1.4

163.97

171.87

pmol/l

0.09

276

2776

Substance abuse

396

3796

1.00

0.01

1.5

136.23

119.88

pmol/l

0.27

388

3696

Complications predominantly related to the puerperium

424

4252

1.00

0.01

1.4

1.5

69.10

113.64

pmol/l

6.66

414

4156

Actinic keratosis

237

2240

1.00

0.01

1.6

1.5

200.94

231.28

pmol/l

0.40

229

2180

Type 2 diabetes

1168

6924

1.00

0.01

1.4

179.62

121.06

pmol/l

2.05

1128

6766

Type 2 diabetes, strict (exclude DM1)

1105

6586

1.00

0.01

1.4

176.69

125.21

pmol/l

1.58

1069

6438

Disorders of optic nerve and visual pathways

848

0.99

0.01

1.7

1.5

142.28

153.77

pmol/l

0.10

830

Maternal care for known or suspected malpresentation of fetus

325

2415

1.00

0.01

1.4

52.19

64.29

pmol/l

1.87

317

2355

Injuries to the elbow and forearm

762

6875

1.00

0.01

1.5

1.4

135.88

136.20

pmol/l

0.01

738

6696

Fracture of lower leg, including ankle

546

5428

1.00

0.01

1.4

132.75

142.87

pmol/l

0.29

524

5307

Postpartum haemorrhage

429

3741

1.00

0.00

1.4

55.22

90.76

pmol/l

5.44

418

3656

Primary open-angle glaucoma

219

2127

1.00

0.00

1.4

1.5

211.51

217.86

pmol/l

0.06

208

2068

Algoneurodystrophy

334

1.02

0.00

1.7

1.5

103.81

178.88

pmol/l

0.76

328

Septal defects

407

0.99

0.00

1.5

97.60

173.47

pmol/l

0.87

396

Pedal cyclist injured in transport accident

175

1747

1.00

0.00

1.5

66.72

141.73

pmol/l

5.22

167

1704

Persistent mood disorders

188

1883

1.00

0.00

1.3

1.4

122.07

148.96

pmol/l

0.37

182

1834

Glucagon-like peptide-1 (GLP-1) analogues

416

3417

1.00

0.00

1.5

1.4

217.30

160.88

pmol/l

0.88

401

3336

Haemangioma and lymphangioma, any site

766

1.01

0.00

1.3

1.5

61.77

175.41

pmol/l

3.96

751

Complications of labour and delivery

1149

6405

1.00

0.00

1.4

100.31

126.99

pmol/l

1.73

1125

6240

Maternal care for other known or suspected fetal problems

426

2736

1.00

0.00

1.4

66.87

65.27

pmol/l

0.06

414

2668

Vitreous haemorrhage

598

1.00

0.00

1.4

1.5

155.09

217.69

pmol/l

0.68

584

Chronic viral hepatitis

311

1.00

0.00

1.4

80.94

110.77

pmol/l

0.37

304

Other/unspecified enthesopathies, not elsewhere classified

715

1.01

0.00

1.5

147.71

160.59

pmol/l

0.15

700

Duodenal ulcer

435

1.01

0.00

1.7

1.5

373.66

223.75

pmol/l

0.58

424

Congenital malformations of the musculoskeletal system, not elsewhere classified

156

1.03

0.00

1.5

1.4

52.31

68.90

pmol/l

1.08

151

Heart failure,strict

318

2293

1.00

0.00

1.5

253.31

189.57

pmol/l

0.89

310

2229

Retinal haemorrhage

128

1.02

0.00

1.2

1.5

163.85

379.65

pmol/l

0.86

128

Haemangioma, any site

710

1.00

0.00

1.3

1.5

62.30

184.00

pmol/l

3.93

697

Autoimmune hyperthyroidism

718

1.00

0.00

1.3

1.5

217.90

171.42

pmol/l

0.13

705

Dentofacial anomalies [including malocclusion]

330

3264

1.00

0.00

1.5

83.22

120.51

pmol/l

2.28

320

3190

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

170

1546

1.00

0.00

1.4

54.91

65.48

pmol/l

0.44

164

1489

Congenital deformities of feet

207

1.01

0.00

1.2

1.4

80.29

146.85

pmol/l

0.57

202

Mild mental retardation

159

1.01

0.00

1.4

88.56

135.18

pmol/l

0.30

154

Congenital malformations of cardiac septa

420

0.99

0.00

1.5

97.08

169.59

pmol/l

0.85

408

Other maltreatment syndromes

175

1.03

0.00

1.4

69.44

126.85

pmol/l

0.45

170

Other accidental hanging and strangulation

0.00

0.0

1.2

—

55.20

—

Other rickettsioses

0.00

0.0

1.3

—

78.17

—

Crushing injury of head

0.00

0.0

1.3

—

77.17

—

0.97

0.00

2.1

1.3

45.57

40.44

pmol/l

—

Other porphyria

0.00

0.0

1.3

—

67.63

—

Taeniasis

0.00

0.0

1.2

—

93.17

—

Autoimmune polyglandular failure

0.00

0.0

1.4

—

35.37

—

Pedestrian injured in collision with other nonmotor vehicle

0.00

0.0

1.4

—

59.57

—

Benign neoplasm: Liver/bile ducts (ICD-9)

0.00

0.0

1.0

—

76.67

—

Other retinal disorders in diseases classified elsewhere

0.00

0.0

1.4

—

44.93

—

Abnormal reflex

1.00

0.00

2.8

1.4

54.80

84.14

pmol/l

—

Polyglandular dysfunction, other/unspecified

0.00

0.0

1.4

—

46.80

—

Malignant neoplasm of anus and anal canal, excluding all cancers (controls excluding all cancers)

0.98

0.00

1.0

1.4

59.00

64.38

pmol/l

—

Vibratory urticaria

0.00

0.0

1.4

—

68.07

—

Other congenital malformations of integument

0.00

0.0

1.2

—

43.83

—

Monocytic leukaemia

0.00

0.0

1.4

—

75.89

—

Accident to watercraft causing other injury

0.00

0.0

1.1

—

66.13

—

Gastroenterology and urology devices associated with adverse incidents

0.00

0.0

1.4

—

87.80

—

Intentional self-harm by drowning and submersion

0.00

0.0

1.3

—

61.00

—

Intentional self-harm by jumping or lying before moving object

0.00

0.0

1.0

—

49.20

—

Discharge of firework

0.00

0.0

2.0

—

46.14

—

Discharge from other and unspecified firearms

0.00

0.0

1.4

—

45.14

—

Myiasis

0.00

0.0

1.3

—

69.43

—

Carcinoma in situ of skin of eyelid, including canthus

0.00

0.0

1.4

—

72.80

—

Pedestrian injured in collision with railway train or railway vehicle

0.00

0.0

1.3

—

56.43

—

Brain mixed glioma

0.00

0.0

1.7

—

55.66

—

Need for immunization against combinations of infectious diseases

0.00

0.0

1.3

—

46.93

—

Mucocutaneous lymph node syndrome [Kawasaki]

0.00

0.0

1.1

—

54.13

—

Pityriasis lichenoides et varioliformis acuta

0.00

0.0

1.3

—

50.34

—

Erysipeloid

0.00

0.0

1.1

—

82.25

—

Benign neoplasm: Other parts of oropharynx

0.89

0.00

3.8

1.3

52.00

61.79

pmol/l

—

Actinic reticuloid

0.00

0.0

1.2

—

70.40

—

Benign neoplasm: Uterine tubes and ligaments

1.02

0.00

1.2

1.3

49.42

60.36

pmol/l

—

Carcinoma in situ of breast

1.00

0.00

1.6

1.3

44.40

66.44

pmol/l

—

Other salmonella infections

260

1.00

0.00

1.4

193.00

231.09

pmol/l

0.15

254

Melanoma in situ of scalp and neck

0.00

0.0

1.8

—

75.90

—

Carcinoma in situ of skin of lip

0.00

0.0

1.8

—

65.05

—

Degeneration of iris and ciliary body

0.00

0.0

1.6

—

48.52

—

Chromomycosis and phaeomycotic abscess

0.00

0.0

1.4

—

66.00

—

Inhalation of gastric contents

0.00

0.0

1.3

—

88.22

—

Huntington disease

0.00

0.0

1.7

—

60.67

—

Coccidioidomycosis

0.00

0.0

2.2

—

93.40

—

Anetoderma (of Jadassohn-Pellizzari/Pasini and pierini)

0.00

0.0

1.2

—

47.00

—

Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism

0.00

0.0

1.3

—

60.00

—

Echinococcosis

0.00

0.0

1.2

—

71.80

—

Disorders of purine and pyrimidine metabolism, other/unspecified

0.00

0.0

1.4

—

55.12

—

Autonomic dysreflexia

0.00

0.0

1.2

—

72.20

—

Classical phenylketonuria

0.00

0.0

1.6

—

70.51

—

Hyperchylomicronaemia

0.00

0.0

1.4

—

136.44

—

Induced delusional disorder

0.00

0.0

1.3

—

51.88

—

Compression of brain

0.00

0.0

1.2

—

60.17

—

Bacterial meningoencephalitis and meningomyelitis

0.00

0.0

1.2

—

59.78

—

Hyperimmunoglobulin E [IgE] syndrome

0.00

0.0

1.4

—

58.00

—

Disorders of fatty-acid metabolism

0.00

0.0

1.3

—

56.71

—

Other chorioretinal disorders in diseases classified elsewhere

0.00

0.0

1.5

—

46.63

—

Palsy of conjugate gaze

0.00

0.0

1.6

—

54.43

—

Hypotony of eye

0.00

0.0

1.1

—

1198.33

—

Hyperalimentation, other specified

0.00

0.0

1.2

—

81.33

—

Choroidal degeneration

0.00

0.0

1.6

—

97.60

—

Disorders of acoustic nerve

0.00

0.0

1.0

—

83.40

—

Other and unspecified disorders of refraction

0.00

0.0

1.3

—

38.29

—

Vertiginous syndromes in diseases classified elsewhere

0.00

0.0

1.0

—

90.07

—

Polyp of middle ear

0.00

0.0

1.6

—

88.60

—

Otitis media in diseases classified elsewhere

0.00

0.0

1.3

—

61.95

—

Abscess of mediastinum

0.00

0.0

1.6

—

80.44

—

Unspecified hairloss

0.00

0.0

1.6

—

77.60

—

Haemoglobinuria due to haemolysis from other external causes

0.00

0.0

1.2

—

70.80

—

Granuloma faciale [eosinophilic granuloma of skin]

0.00

0.0

1.2

—

65.40

—

Other transepidermal elimination disorders

0.00

0.0

1.2

—

67.40

—

Café au lait spots

0.00

0.0

1.9

—

51.00

—

Disorders of puberty

0.99

0.00

1.5

1.3

33.38

44.53

pmol/l

—

Common variable immunodeficiency with autoantibodies to B- or T-cells

0.00

0.0

1.2

—

70.80

—

Other chronic figurate erythema

0.00

0.0

1.0

—

66.40

—

Erythrasma

0.00

0.0

1.1

—

68.73

—

Other disorders of bone development and growth

0.00

0.0

1.2

—

51.00

—

Disorders of puberty, all

0.93

0.00

1.4

1.3

34.56

44.72

pmol/l

—

Other deformity of hallux (acquired)

0.88

0.00

2.0

1.3

72.00

380.51

pmol/l

—

Hereditary factor XI deficiency

0.00

0.0

1.3

—

72.50

—

Pseudosarcomatous fibromatosis

0.00

0.0

1.3

—

77.88

—

Hereditary factor IX deficiency

0.00

0.0

1.5

—

70.50

—

Interstitial myositis

0.00

0.0

1.3

—

90.17

—

Severe combined immunodeficiency [SCID] with low T- and B-cell numbers

0.00

0.0

1.5

—

62.63

—

Sequelae of complication of pregnancy, childbirth and the puerperium

0.00

0.0

1.9

—

44.75

—

Other migraine, drug-induced

0.00

0.0

1.4

—

62.40

—

Malnutrition in pregnancy

0.00

0.0

1.4

—

42.14

—

Asphyxiation

0.00

0.0

1.2

—

51.50

—

Phlebitis and thrombophlebitis of other sites, drug-induced

0.00

0.0

1.0

—

62.40

—

Malignant neoplasm of ureter

0.00

0.0

1.1

—

104.43

—

Use of apomorphine

0.00

0.0

1.3

—

70.83

—

Medullary carcinoma of thyroid gland

0.00

0.0

1.3

—

80.89

—

Use of pergolide

0.00

0.0

1.0

—

86.17

—

Hereditary angioödema type 1

0.00

0.0

1.2

—

52.89

—

Other conditions originating in the perinatal period

0.00

0.0

1.3

—

44.29

—

Alport

0.00

0.0

1.3

—

51.00

—

Malignant neoplasm of oropharyng

0.00

0.0

1.2

—

75.17

—

Malignant neoplasm of nasopharynx

0.00

0.0

1.2

—

58.00

—

Anencephaly and similar malformations

0.00

0.0

1.3

—

48.33

—

Brain mixed glioma, excluding all cancers (controls excluding all cancers)

0.00

0.0

1.4

—

44.80

—

Congenital malformation of optic disc

0.00

0.0

1.4

—

86.00

—

Congenital glaucoma

0.00

0.0

1.4

—

77.70

—

Noonan syndrome

0.00

0.0

1.3

—

41.45

—

Polydactyly

0.00

0.0

1.4

—

64.00

—

Other congenital malformations of eye

0.00

0.0

1.3

—

72.73

—

Sequelae of poisoning by drugs, medicaments and biological substances

0.00

0.0

1.2

—

55.89

—

Traumatic secondary and recurrent haemorrhage

0.00

0.0

1.1

—

79.29

—

Traumatic amputation of hip and thigh

0.00

0.0

1.4

—

88.60

—

Fat embolism (traumatic)

0.00

0.0

1.0

—

140.24

—

Injury of blood vessels at ankle and foot level

0.00

0.0

1.2

—

59.00

—

ICD 8 haemorrhage (epidural, subarachnoid, subduralis)

0.00

0.0

1.3

—

79.23

—

Fracture of upper limb, level unspecified

0.00

0.0

1.0

—

76.80

—

Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis

0.00

0.0

1.6

—

57.51

—

Multiple superficial injuries of ankle and foot

0.00

0.0

1.3

—

49.89

—

Colorectal squamous cell carcinoma, excluding all cancers (controls excluding all cancers)

0.00

0.0

1.1

—

66.78

—

Myxoedema coma

0.00

0.0

1.4

—

70.40

—

Disorders of aromatic amino-acid metabolism, other/unspecified

0.00

-0.00

0.0

1.2

—

45.17

—

Hydroxyapatite deposition disease

0.00

-0.00

0.0

1.3

—

68.75

—

Squamous cell neoplasms and carcinoma of rectum, excluding all cancers (controls excluding all cancers)

0.00

-0.00

0.0

1.1

—

66.78

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Human epididymis protein 4 [Moles/volume] in Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS