Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

CD2_BENIGN_EAR_NASAL_SINUS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D14.0&
  • Hospital discharge: ICD-9 2120
  • Hospital discharge: ICD-8 2120
  • Cause of death: ICD-10 D14.0&
  • Cause of death: ICD-9 2120
  • Cause of death: ICD-8 2120

2 out of 7 registries used, show all original rules.

1689

4. Check minimum number of events

None

1689

5. Include endpoints

None

1689

6. Filter based on genotype QC (FinnGen only)

1533

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum auris mediae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9658 4526 5061
Only index persons 8673 4172 4501
Unadjusted period prevalence (%)
Whole population 0.14 0.13 0.14
Only index persons 0.16 0.15 0.17
Median age at first event (years)
Whole population 53.85 54.43 53.29
Only index persons 52.85 53.43 52.31

-FinnGen-

Key figures

All Female Male
Number of individuals 1533 726 807
Unadjusted period prevalence (%) 0.32 0.26 0.37
Median age at first event (years) 56.96 55.24 58.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1588
Matched controls
15880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
DHA10
NOMESCO Finland
Biopsy of cavity of nose
85.1
307.7
281
40
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
4503599627370496.0
307.7
1418
*
DHB10
NOMESCO Finland
Excision of lesion of internal nose
282.4
307.7
260
11
UDH02
NOMESCO Finland
Rhinopharyngoscopy
11.4
307.7
471
567
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
131.9
285.9
144
12
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
10.4
263.9
325
382
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
14.2
213.3
204
163
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
10.4
205.1
246
276
UDM02
NOMESCO Finland
Sinoscopy
15.2
203.6
186
137
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
81.2
185.7
99
13
J33.0
ICD-10 Finland
Polyp of nasal cavity
9.6
156.0
195
229
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
5.2
119.0
276
615
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
19.1
109.5
87
48
DPA30
NOMESCO Finland
Sphenotomy
22.8
103.4
76
35
J33.8
ICD-10 Finland
Other polyp of sinus
9.3
103.2
129
150
DHB40
NOMESCO Finland
Conchotomy
53.7
99.6
57
11
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.2
99.3
309
864
DHB20
NOMESCO Finland
Polypectomy of internal nose
10.5
92.3
104
105
2120A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Nasal cavities, middle ear and accessory sinuses
+∞
91.6
87
*
DMB10
NOMESCO Finland
Radical maxillary antrotomy
23.4
86.7
63
28
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
18.9
78.0
62
34
J33.9
ICD-10 Finland
Nasal polyp, unspecified
10.9
75.0
82
79
D14.1
ICD-10 Finland
Benign neoplasm: Larynx
16.2
74.7
64
41
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.9
73.3
139
255
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
6.6
70.9
118
190
R01AD08
ATC
fluticasone; nasal
2.6
69.9
593
2941
J34.8
ICD-10 Finland
Other specified disorders of nose and nasal sinuses
11.1
63.1
68
64
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
319.6
60.8
61
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
158.5
58.3
61
*
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
70.3
53.5
61
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
49.0
517
2748
ZXC10
NOMESCO Finland
Use of laser
6.3
47.7
82
136
R01AD09
ATC
mometasone; nasal
2.1
47.6
803
5134
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
46.2
695
4237
DHB00
NOMESCO Finland
Excision of lesion of external nose
9.6
45.6
54
58
R04.0
ICD-10 Finland
Epistaxis
3.1
43.3
201
711
DMB30
NOMESCO Finland
Transmaxillary excision of lesion of maxillary antrum
226.1
43.1
44
*
J31.0
ICD-10 Finland
Chronic rhinitis
3.1
43.1
201
713
ZXE00
NOMESCO Finland
One hour or less
2.1
41.4
694
4357
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.5
40.9
151
464
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
9.9
40.5
47
49
21202
ICD-8 Finland
Benign neoplasm of respiratory system, Sinus maxillaris
+∞
39.7
38
*
DMB35
NOMESCO Finland
Endoscopic excision of neoplasm or another lesion from maxillary sinus
396.9
39.2
39
*
21200
ICD-8 Finland
Benign neoplasm of respiratory system, Cavi nasi
+∞
38.7
37
*
DJW00
NOMESCO Finland
Removal of local lesion of nasal septum
73.4
38.1
43
6
DKW40
NOMESCO Finland
Ligature of artery of internal nose
94.7
33.9
37
*
Z2221
NOMESCO Finland
Medical doctor
2.0
33.7
484
2829
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
33.4
632
4058
ZXC95
NOMESCO Finland
Use of surgical navigator
7.5
33.2
48
66
4256
FHL
Nasal or sinus tumor removal
333.8
33.0
33
*
R01AD12
ATC
fluticasone furoate; nasal
1.9
30.9
520
3194
ZXD20
NOMESCO Finland
Day surgery
2.4
30.3
248
1157
J34.1
ICD-10 Finland
Cyst and mucocele of nose and nasal sinus
6.0
30.2
54
93
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
28.8
859
6266
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
44.7
28.8
35
8
H02AB06
ATC
prednisolone; systemic
1.8
28.4
808
5805
B977, D140,
ICD-10 Finland
+∞
28.2
27
*
WX402
NOMESCO Finland
General anaesthesia
2.0
27.8
403
2339
ZXA05
NOMESCO Finland
Left side
1.9
27.8
436
2601
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
26.9
352
1970
DNB40
NOMESCO Finland
Sublabial rhinotomy
+∞
26.1
25
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.9
25.6
399
2365
DHB50
NOMESCO Finland
Turbinoplasty
4.0
24.4
70
180
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
23.8
1139
9287
J32.1
ICD-10 Finland
Chronic frontal sinusitis
8.7
23.7
30
35
DJA10
NOMESCO Finland
Biopsy of septum of nose
126.9
23.6
25
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.5
23.1
82
245
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
45.7
22.4
27
6
WX002
NOMESCO Finland
Sedation and analgesia
1.9
21.9
339
1992
ZXA00
NOMESCO Finland
Right side
1.8
21.8
446
2855
UDQ22
NOMESCO Finland
Microlaryngoscopy
6.9
21.3
33
49
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
6.5
21.0
34
53
D36.7
ICD-10 Finland
Benign neoplasm: Other specified sites
19.1
20.0
30
16
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
15.5
19.8
32
21
R08
ICPC
Nose symptom/complaint other
3.2
19.8
78
249
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
106.4
19.6
21
*
ZXA10
NOMESCO Finland
Bilateral
1.9
19.4
309
1827
DPW99
NOMESCO Finland
Other operation on frontal or sphenoidal sinus
28.2
18.7
25
9
DPB00
NOMESCO Finland
Partial excision of frontal sinus
70.8
18.7
21
*
D10.6
ICD-10 Finland
Benign neoplasm: Nasopharynx
27.0
17.8
24
9
J32.4
ICD-10 Finland
Chronic pansinusitis
4.5
17.8
43
97
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
17.3
237
1331
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
17.2
557
3983
DKW30
NOMESCO Finland
Cauterisation of artery of internal nose
6.9
17.0
26
38
J34.2
ICD-10 Finland
Deviated nasal septum
2.5
17.0
112
471
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.8
17.0
86
317
R01AD58
ATC
fluticasone, combinations; nasal
1.7
16.9
372
2409
J01DB01
ATC
cefalexin; oral
1.8
16.8
1286
11250
DMB40
NOMESCO Finland
Excision of lesion of maxillary antrum trough lateral rhinotomy
+∞
16.7
16
*
R06AE07
ATC
cetirizine; oral
1.6
16.6
649
4842
UDC00
NOMESCO Finland
Ear microscopy
2.2
16.3
137
642
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.1
15.6
67
225
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
26.6
15.6
21
8
4226
FHL
Posterior radical surgery and possible etmoidectomy
6.0
15.3
27
46
J01AA02
ATC
doxycycline; systemic
1.6
15.2
1206
10464
8070/3-C30.0
ICD-O-3
Squamous cell carcinoma, NOS, of nasal cavity
45.5
15.1
18
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
15.0
772
6076
4222
FHL
Endonasal etmoidectomy
6.6
14.9
24
37
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.0
14.6
161
836
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
80.9
14.6
16
*
DPC35
NOMESCO Finland
Extensive endoscopic excision of lesion or neoplasm extending to more than one paranasal sinus
80.9
14.6
16
*
R01AD01
ATC
beclometasone; nasal
1.8
14.6
241
1432
DPA20
NOMESCO Finland
Trephine of frontal sinus
22.5
14.2
20
9
R51.81
ICD-10 Finland
Facial pain NOS
3.4
14.0
50
150
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
4.8
13.6
30
63
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
13.5
675
5244
J01CA04
ATC
amoxicillin; systemic
1.6
13.3
1241
10958
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.9
13.2
60
209
R4110
NOMESCO Finland
Physiotherapy
1.6
13.1
432
3065
A02BC02
ATC
pantoprazole; systemic
1.5
13.1
1060
9053
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
10.1
13.0
25
25
G50.1
ICD-10 Finland
Atypical facial pain
3.7
13.0
40
109
D38.58
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other respiratory organ
50.4
12.9
15
*
J01FA10
ATC
azithromycin; systemic
1.5
12.7
822
6691
B07.9
ICD-10 Finland
Verruca simplex
2.7
12.7
66
247
DMA10
NOMESCO Finland
Exploration of maxillary antrum
32.3
12.6
16
5
J01.1
ICD-10 Finland
Acute frontal sinusitis
3.9
12.4
36
94
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
3.5
12.4
43
127
A07AA02
ATC
nystatin; oral
2.3
12.3
98
449
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
12.2
639
4982
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
12.0
402
2855
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.4
11.9
78
328
N02BE01
ATC
paracetamol; systemic, rectal
1.7
11.8
1387
12697
J33
ICD-10 Finland
Nasal polyp
5.2
11.8
24
47
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
11.7
252
1609
Z3231
NOMESCO Finland
Registered nurse
1.5
11.6
406
2906
WF002
NOMESCO Finland
Radical radiotherapy
2.2
11.3
98
465
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.2
652
5158
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
11.2
135
724
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
4.1
11.2
30
74
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.0
661
5257
DQA10
NOMESCO Finland
Biopsy of larynx
5.4
10.9
21
39
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
10.7
100
489
DKW99
NOMESCO Finland
Other procedures for control of epistaxis
13.0
10.7
18
14
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.7
10.5
33
91
DCB00
NOMESCO Finland
Excision of lesion of middle ear
110.7
10.4
11
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
10.4
272
1819
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
10.3
74
325
R03AC02
ATC
salbutamol; inhalant
1.4
10.2
803
6674
H65.3
ICD-10 Finland
Chronic mucoid otitis media
3.3
10.0
37
114
UDQ02
NOMESCO Finland
Direct laryngoscopy
4.7
10.0
23
50
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.9
283
1930
R01AD05
ATC
budesonide; nasal
1.9
9.9
117
624
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
9.8
447
3359
S29
ICPC
Skin symptom/complaint other
1.5
9.8
303
2102
Z01.2
ICD-10 Finland
Dental examination
1.4
9.7
654
5274
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
9.7
553
4333
M31.3
ICD-10 Finland
Wegener granulomatosis
13.5
9.7
16
12
D14.4
ICD-10 Finland
Benign neoplasm: Respiratory system, unspecified
55.3
9.7
11
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.5
9.6
59
241
R06AX22
ATC
ebastine; oral
1.6
9.5
243
1613
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
9.5
78
362
J01DA01
ATC
[U] cefalexin
1.4
9.5
905
7731
DPB10
NOMESCO Finland
Partial excision of sphenoidal sinus
100.6
9.4
10
*
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
9.4
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
9.3
339
2433
H02AB04
ATC
methylprednisolone; systemic
1.6
9.2
212
1372
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
9.2
1356
12510
R03DC03
ATC
montelukast; oral
1.6
9.1
235
1562
J01DC02
ATC
cefuroxime; systemic
2.2
9.1
79
375
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
9.1
287
2000
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.4
9.0
61
261
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
4.1
9.0
24
59
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
9.0
532
4182
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
9.0
68
306
A02BC03
ATC
lansoprazole; oral
1.4
8.9
423
3194
J45
ICD-10 Finland
Asthma
1.8
8.9
147
870
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.9
338
2448
A03
ICPC
Fever
1.6
8.8
231
1541
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.0
8.8
97
505
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
4.2
8.7
23
56
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.8
8.5
123
699
J01FA09
ATC
clarithromycin; systemic
1.4
8.5
431
3289
R05
ICPC
Cough
1.5
8.5
355
2617
C72.2
ICD-10 Finland
Malignant neoplasm: Olfactory nerve
90.5
8.4
9
*
Z3226
NOMESCO Finland
Physiotherapist
1.5
8.4
260
1801
N03
ICPC
Pain face
4.5
8.4
20
45
J32.2
ICD-10 Finland
Chronic ethmoidal sinusitis
4.5
8.4
20
45
1210
FHL
Anthroscopy
12.8
8.4
14
11
4239
FHL
Other measure in this category
7.9
8.4
18
23
DPA40
NOMESCO Finland
Excision of lesion or neoplasm from sphenoid sinus
+∞
8.3
8
*
DPA35
NOMESCO Finland
Endoscopic excision of lesion or neoplasm from frontal sinus
+∞
8.3
8
*
9522/3-C30.0
ICD-O-3
Olfactory neuroblastoma of nasal cavity
+∞
8.3
8
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
8.3
372
2774
R21
ICPC
Throat symptom/complaint
1.5
8.3
259
1796
A02BC01
ATC
omeprazole; systemic
1.4
8.3
388
2918
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.3
779
6580
WF003
NOMESCO Finland
Adjuvant radiotherapy
2.3
8.2
58
253
S21
ICPC
Skin texture symptom/complaint
1.6
8.2
220
1476
UJH02
NOMESCO Finland
Anoscopy
2.2
8.2
66
305
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
8.1
127
741
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
8.1
214
1431
ZZC00
NOMESCO Finland
Graft of fascia
33.5
8.1
10
*
E0000UV, ,
ATC
1.4
8.1
580
4690
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
8.1
108
600
A02BC05
ATC
esomeprazole; systemic
1.4
8.1
584
4728
J01FA06
ATC
roxithromycin; oral
1.4
8.1
561
4513
UJF32
NOMESCO Finland
Coloscopy
1.4
8.1
383
2887
J01MA12
ATC
levofloxacin; systemic
1.5
8.0
276
1953
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
8.0
83
422
R05
ICD-10 Finland
Cough
1.5
8.0
307
2222
DC1AD
NOMESCO Finland
Temporalbone CT
3.9
8.0
23
60
H02AB07
ATC
prednisone; oral
1.6
7.9
195
1281
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.8
1029
9118
EMA30
NOMESCO Finland
Biopsy of rhinopharynx
10.9
7.8
14
13
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.8
420
3235
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
7.0
7.8
18
26
S81.9
ICD-10 Finland
Open wound of lower leg, part unspecified
4.2
7.7
20
48
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
7.7
402
3077
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.7
781
6645
J01FF01
ATC
clindamycin; systemic
1.4
7.6
393
3000
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.6
826
7097
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
7.5
258
1823
ZXD05
NOMESCO Finland
Urgent procedure
1.4
7.5
421
3264
DJB10
NOMESCO Finland
Excision of septum of nose
80.5
7.4
8
*
D35.59
ICD-10 Finland
Other paragangliom
80.5
7.4
8
*
B977, D141,
ICD-10 Finland
80.5
7.4
8
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
3.6
7.3
23
64
B01AB05
ATC
enoxaparin; parenteral
1.4
7.3
449
3529
R51.80
ICD-10 Finland
Headache
1.5
7.3
210
1430
EEB10
NOMESCO Finland
Maxillectomy
+∞
7.3
7
*
21209
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, NUD
+∞
7.3
7
*
21208
ICD-8 Finland
Benign neoplasm of respiratory system, Nasi, loco multiplici
+∞
7.3
7
*
DJD20
NOMESCO Finland
Plastic repair of septum of nose
2.1
7.3
64
307
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
5.8
7.2
19
33
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
4.3
7.2
18
42
D01
ICPC
Abdominal pain/cramps general
1.6
7.2
165
1066
KMAK, ,
NOMESCO Finland
1.3
7.2
694
5841
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
4.5
7.2
17
38
R03BA02
ATC
budesonide; inhalant
1.5
7.1
251
1784
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.1
642
5349
G47.3
ICD-10 Finland
Sleep apnoea
1.4
7.1
346
2615
J01
ICD-10 Finland
Acute sinusitis
2.0
7.1
78
407
R06.0
ICD-10 Finland
Dyspnoea
1.4
7.1
406
3154
N05CF01
ATC
zopiclone; oral
1.4
7.0
458
3629
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.9
162
1051
D07AC01
ATC
betamethasone; topical
1.4
6.9
514
4156
N07BA03
ATC
varenicline; oral
2.0
6.9
70
355
M79.1
ICD-10 Finland
Myalgia
1.5
6.8
201
1375
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.8
628
5238
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.8
925
8148
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.4
6.8
43
179
H65.2
ICD-10 Finland
Chronic serous otitis media
3.2
6.7
26
83
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
6.7
121
735
J32.8
ICD-10 Finland
Other chronic sinusitis
7.2
6.7
15
21
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
2.4
6.7
46
199
R06AX27
ATC
desloratadine; oral
1.4
6.7
369
2844
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.7
400
3124
4711A
ICD-9 Finland
Nasal polyps, Polypoid sinus degeneration
6.5
6.6
16
25
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.8
6.6
89
496
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
5.9
6.6
17
29
50300
ICD-8 Finland
Chronic sinusitis, Maxillaris cum empyemate
5.9
6.6
17
29
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.6
813
7052
A11
ICPC
Chest pain NOS
1.7
6.6
128
793
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.6
575
4753
SAA04
NOMESCO Finland
Special examination of mouth
1.9
6.6
77
410
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
6.6
158
1033
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
2.2
6.6
53
246
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
6.6
374
2897
J32.3
ICD-10 Finland
Chronic sphenoidal sinusitis
8.7
6.6
13
15
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.5
179
1206
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
6.5
306
2293
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.5
162
1068
R09
ICPC
Sinus symptom/complaint
1.7
6.5
110
657
J01DA06
ATC
[U] cefuroxime
1.5
6.5
192
1315
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
3.1
6.5
26
85
8720/3-C30.0
ICD-O-3
Malignant melanoma, NOS, of nasal cavity
70.1
6.4
7
*
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
6.4
51
235
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.3
6.4
23
70
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.7
6.4
106
629
4610A
ICD-9 Finland
Acute sinusitis, Maxillary
3.0
6.4
27
91
G04CB01
ATC
finasteride; oral
1.6
6.4
167
1113
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
4.1
6.4
17
42
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.3
195
1347
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.5
6.3
38
155
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
6.3
99
579
DM1BG
NOMESCO Finland
Paranasal sinuses and face area standard MRI examination with high intensity magnet
+∞
6.3
6
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
6.2
264
1941
J02AC01
ATC
fluconazole; systemic
1.3
6.2
485
3939
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.2
252
1840
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.8
6.2
29
104
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.2
6.2
23
72
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.3
6.1
22
67
XF402
NOMESCO Finland
ECG with work load test
1.6
6.1
153
1009
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.1
91
524
4252
FHL
Resection, coagulation or cryo on the cortex and nasal mucosa
12.6
6.1
10
8
A98
ICPC
Health maint/preventive medicine
1.7
6.1
1478
14142
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.2
6.0
49
228
ZXC60
NOMESCO Finland
Application of heat
2.8
6.0
28
100

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
912
5452
2.58
73.36
2.9
2.2
—
—
—
0
0
316
1695
2.08
27.13
2.0
1.8
—
—
—
0
0
245
1257
2.12
23.41
1.5
1.4
—
—
—
0
0
587
4074
1.70
21.46
3.6
3.3
0.40
0.45
e6/l
0.25
438
3015
357
2154
1.85
21.18
2.3
2.1
—
—
—
0
0
321
1890
1.88
20.51
1.3
1.3
—
—
—
0
0
553
3854
1.67
19.46
3.5
3.2
—
0.00
estimate
—
0
16
830
6437
1.61
18.71
5.6
5.4
35.57
35.48
g/l
0.18
785
6036
636
4736
1.57
16.32
3.8
3.4
75.77
82.64
e6/l
0.06
481
3653
826
6524
1.55
16.30
7.6
7.1
1.21
1.21
mmol/l
1.21
785
6040
696
5324
1.55
15.65
4.6
4.1
59.73
118.68
e6/l
1.53
491
3827
588
4378
1.54
14.69
4.8
4.3
7.40
7.40
ph
0.27
439
3174
567
4230
1.53
13.83
7.3
6.4
—
—
—
0
0
1175
10215
1.58
13.81
5.1
4.4
12.64
12.42
mm/h
0.19
1104
9548
1223
10736
1.61
13.75
10.0
8.6
80.35
79.90
u/l
0.13
1165
10216
636
4879
1.51
13.51
6.8
6.4
—
—
—
0
0
1128
9736
1.55
13.50
4.8
4.3
0.20
4392.39
—
5
23
499
3636
1.54
13.50
4.9
4.3
89.06
88.36
%
0.26
488
3566
920
7609
1.50
13.49
7.2
6.9
12.15
11.71
umol/l
0.28
874
7285
372
2542
1.61
13.28
3.5
3.0
0.73
1.04
e6/l
2.54
210
1360
964
8075
1.49
13.09
11.1
9.9
4.27
4.17
e9/l
0.58
825
7019
882
7259
1.48
13.07
8.1
7.8
1.21
1.21
mmol/l
0.51
758
6258
642
4961
1.49
13.03
3.5
3.6
2.35
2.35
mmol/l
0.14
591
4510
812
6610
1.47
12.48
2.8
2.9
—
—
estimate
—
0
0
408
2886
1.56
12.44
3.0
3.0
2.45
2.45
mmol/l
0.22
356
2606
261
1659
1.69
12.32
2.8
2.8
5.70
8.20
umol/l
3.95
226
1488
344
2354
1.59
12.07
3.7
3.1
1.97
2.14
e6/l
0.14
176
1172
762
6211
1.44
11.15
13.7
12.0
0.00
0.00
e9/l
0.45
604
5081
863
7215
1.43
10.87
7.6
6.4
0.61
0.59
e9/l
1.19
723
6190
863
7230
1.42
10.65
7.6
6.4
0.04
0.04
e9/l
0.39
725
6205
804
6653
1.42
10.63
7.8
6.7
9.01
8.95
%
0.21
752
6242
801
6639
1.42
10.41
7.8
6.6
2.98
2.84
%
0.83
747
6230
800
6643
1.41
10.21
7.8
6.7
0.69
0.68
%
0.15
747
6229
882
7453
1.41
10.16
7.9
6.7
0.20
0.19
e9/l
0.52
760
6513
871
7353
1.41
10.03
7.7
6.5
1.87
1.92
e9/l
0.35
753
6472
442
3305
1.47
10.00
2.7
2.7
3.96
5.19
e6/l
2.14
392
3025
1227
11031
1.49
9.95
26.0
21.0
13.79
13.68
%
1.88
1217
10884
812
6787
1.40
9.83
7.9
6.6
26.73
27.15
%
0.51
765
6442
537
4183
1.43
9.71
5.0
4.5
—
—
—
0
0
262
1770
1.58
9.53
1.7
1.5
—
—
—
0
0
348
2505
1.50
9.46
4.3
3.5
0.81
0.82
mmol/l
0.08
328
2376
1425
13291
1.70
9.42
21.7
17.1
23.83
25.30
mg/l
0.93
1235
11056
1028
8996
1.40
9.21
5.4
4.8
3303.38
1324.46
e6/l
—
8
126
972
8426
1.40
9.20
6.2
5.5
6.70
6.74
mmol/l
0.29
930
8049
165
1020
1.69
8.55
1.3
1.5
—
—
—
0
0
208
1380
1.58
8.13
3.0
2.4
32.81
75.83
u/l
0.65
170
1158
281
2001
1.49
7.93
1.3
1.3
—
—
—
0
0
574
4649
1.37
7.85
2.5
2.6
—
—
—
0
0
204
1359
1.57
7.83
3.1
2.2
367.58
377.77
nmol/l
0.32
196
1260
782
6656
1.34
7.68
7.8
6.5
57.72
57.70
%
0.01
748
6365
109
622
1.81
7.49
3.0
1.4
10.40
11.79
iu/ml
—
10
17
1448
13691
1.65
7.46
25.2
20.6
3.97
3.98
mmol/l
1.36
1433
13404
1446
13669
1.65
7.43
25.1
20.4
139.59
139.67
mmol/l
0.59
1432
13407
177
1158
1.59
7.33
2.8
2.9
10.25
10.77
g/l
0.97
161
1067
794
6812
1.33
7.22
18.5
15.9
1.27
1.27
inr
0.00
687
5716
1054
9430
1.35
7.16
5.1
4.6
—
3.34
—
0
15
1143
10361
1.37
7.09
4.8
4.3
14.87
14.86
pmol/l
0.01
1063
9487
567
4644
1.34
7.02
2.7
2.7
57.67
78.37
u/l
0.63
535
4323
371
2847
1.40
6.92
3.4
3.0
547.81
533.38
mosm/kgh2o
0.64
317
2490
473
3779
1.36
6.87
2.7
2.3
2.86
2.88
mg/l
0.04
416
3257
1327
12357
1.45
6.87
6.0
5.3
1.90
1.94
mu/l
0.47
1238
11398
746
6382
1.32
6.75
3.7
3.1
145.21
139.25
ug/l
0.15
705
5931
555
4555
1.34
6.71
2.1
2.2
181.15
218.37
u/l
0.81
526
4318
734
6290
1.31
6.46
2.7
2.4
77.57
77.46
nmol/l
0.04
666
5670
91
528
1.77
5.96
1.5
1.2
—
—
—
0
0
304
2311
1.39
5.91
2.4
2.1
29.82
29.69
s
0.14
297
2246
295
2235
1.39
5.85
1.8
1.8
—
—
—
0
0
1478
14163
1.63
5.76
27.3
22.3
80.21
79.88
umol/l
0.11
1467
13999
46
215
2.17
5.63
2.8
2.5
—
—
—
0
0
33
133
2.51
5.63
1.5
1.1
—
—
—
0
0
201
1431
1.46
5.62
1.6
1.5
—
—
—
0
0
741
6437
1.28
5.60
2.3
2.2
95.41
95.33
pmol/l
0.01
396
3464
304
2332
1.38
5.58
2.6
2.7
2.27
2.29
g/l
0.21
279
2176
285
2182
1.37
5.27
2.7
2.7
20.99
22.92
%
1.82
267
2053
392
3153
1.32
5.23
1.9
1.7
1.23
1.28
mg/l
0.14
325
2459
321
2509
1.35
5.20
2.7
2.7
11.91
12.94
umol/l
1.84
302
2353
189
1351
1.45
5.17
11.0
9.7
—
—
—
0
0
1464
14041
1.55
5.16
14.8
12.6
26.02
26.74
u/l
1.08
1430
13646
267
2030
1.38
5.15
5.3
6.2
1.04
1.03
mmol/l
0.22
247
1887
229
1700
1.41
5.09
2.3
2.5
165.68
136.44
ug/g
0.65
189
1362
68
381
1.82
5.04
2.9
3.6
3.50
1.91
index
0.60
38
204
207
1513
1.42
5.02
1.5
1.6
—
—
—
0
0
433
3549
1.30
5.01
2.5
2.5
—
—
—
0
0
462
3822
1.29
4.98
3.3
2.9
357.47
348.99
umol/l
0.99
408
3366
239
1795
1.39
4.96
9.2
8.9
5.09
5.10
kpa
0.05
230
1730
239
1796
1.39
4.94
9.2
8.9
13.00
12.07
kpa
1.46
229
1733
568
4830
1.27
4.91
3.6
3.4
33.11
34.18
u/l
0.16
534
4573
66
370
1.82
4.89
1.2
1.2
—
—
—
0
0
162
1138
1.47
4.85
3.0
3.0
207.17
205.37
ng/l
0.02
151
1041
353
2829
1.32
4.79
4.5
4.0
250.66
400.62
ng/l
0.82
280
2252
831
7411
1.25
4.73
4.6
4.0
8.83
3.12
estimate
0.28
184
1615
236
1783
1.38
4.72
9.2
8.9
1.11
0.96
mmol/l
0.26
196
1470
97
612
1.62
4.72
1.2
1.3
—
—
—
0
0
248
1890
1.37
4.70
1.5
1.6
—
—
—
0
0
835
7459
1.25
4.66
4.6
4.0
0.00
0.22
estimate
0.56
174
1502
1363
12946
1.37
4.61
5.7
5.3
6.02
6.00
mmol/l
0.18
1282
11851
135
924
1.50
4.60
1.7
1.8
1.29
1.39
g/l
0.27
120
854
101
651
1.59
4.51
1.1
1.1
—
—
—
0
0
1493
14430
1.58
4.51
32.1
25.8
247.97
247.40
e9/l
0.12
1476
14148
1493
14432
1.58
4.48
32.0
25.7
91.10
91.30
fl
1.03
1487
14269
1493
14435
1.57
4.44
32.1
25.8
4.49
4.49
e12/l
0.08
1469
14103
1493
14438
1.57
4.40
32.3
26.0
134.79
135.48
g/l
0.95
1487
14277
228
1734
1.37
4.38
2.4
2.7
1.81
1.82
%
0.06
207
1562
339
2739
1.30
4.30
1.6
1.5
2.38
2.56
g/l
1.01
204
1703
1492
14435
1.56
4.28
32.0
25.7
30.27
30.40
pg
2.50
1486
14271
1492
14435
1.56
4.28
33.0
26.4
40.45
40.38
%
0.20
1486
14265
1492
14436
1.55
4.27
32.2
25.9
6.97
6.77
e9/l
2.01
1469
14103
30
133
2.28
4.23
2.2
1.3
—
—
—
0
0
817
7328
1.24
4.22
4.6
3.9
0.00
0.00
estimate
-0.00
178
1582
44
229
1.95
4.13
2.5
1.7
0.97
0.81
g/l
0.22
34
183
233
1794
1.35
4.13
9.4
8.9
7.42
7.41
ph
0.73
133
1005
56
316
1.80
4.11
1.1
1.2
—
—
—
0
0
80
499
1.64
4.11
1.4
1.4
29.20
27.08
iu/l
0.22
62
418
40
202
2.01
4.09
1.1
1.1
0.41
2.11
u/ml
2.24
28
106
1339
12749
1.32
3.93
7.2
6.6
39.65
39.61
mmol/mol
0.05
1267
11920
211
1615
1.35
3.89
9.8
9.3
95.74
95.56
%
0.19
203
1564
29
134
2.19
3.74
2.1
1.3
0.36
0.39
g/l
0.27
21
97
29
134
2.19
3.74
2.1
1.3
3.39
2.89
g/l
0.65
21
97
29
134
2.19
3.74
2.1
1.3
6.64
6.92
g/l
0.18
21
99
198
1511
1.35
3.72
10.3
9.8
119.49
121.30
g/l
0.56
193
1476
47
260
1.83
3.71
1.4
1.7
—
—
—
0
0
138
993
1.43
3.68
12.2
11.2
0.61
0.64
%
0.40
138
987
1000
9240
1.22
3.61
3.5
3.5
47.27
52.06
u/l
1.17
946
8694
525
4556
1.23
3.54
3.3
3.2
1275.02
1351.18
ng/l
0.19
456
3927
39
208
1.90
3.46
1.1
1.1
0.36
1.61
u/ml
1.31
21
91
456
3908
1.23
3.45
3.3
3.1
0.00
0.02
—
6
98
662
5895
1.21
3.42
4.1
3.5
6.30
6.21
ph
1.04
342
3354
119
847
1.44
3.39
1.2
1.3
67.30
54.30
au/ml
—
10
65
39
211
1.87
3.32
1.1
1.1
3.16
4.04
u/ml
0.22
23
113
63
392
1.63
3.32
2.0
2.2
10.42
12.17
mg/l
1.20
56
364
128
928
1.41
3.30
2.3
2.5
14.17
19.29
au/ml
0.46
15
98
142
1051
1.39
3.25
2.7
2.6
—
—
—
0
0
37
199
1.88
3.22
1.3
1.3
0.65
9.61
nmol/l
0.50
37
190
169
1289
1.35
3.21
2.7
2.9
64.88
66.55
g/l
2.40
156
1196
139
1029
1.38
3.18
12.2
11.0
94.01
93.72
%
0.28
139
1022
44
252
1.77
3.14
1.1
1.1
1.20
1.99
u/ml
0.42
27
146
25
118
2.14
3.11
1.2
1.2
0.37
1.27
u/ml
0.83
14
65
20
86
2.34
3.08
1.1
1.0
—
—
—
0
0
176
1366
1.32
2.98
2.4
2.8
77.00
69.85
e9/l
1.49
124
1018
201
1593
1.30
2.93
4.3
3.8
7.38
7.38
ph
0.14
116
923
61
390
1.59
2.92
2.1
1.7
285.67
279.56
mu/l
0.07
52
354
79
536
1.50
2.90
2.9
2.5
10.20
10.66
g/l
0.52
74
488
32
171
1.89
2.87
2.0
1.7
21.48
31.20
ng/l
0.72
32
171
109
796
1.40
2.73
2.8
3.5
4.33
4.49
pmol/l
0.98
97
706
172
1348
1.31
2.73
2.2
2.4
13.13
13.35
nmol/l
0.13
155
1221
164
1280
1.31
2.68
2.2
2.4
7.76
7.32
ug/l
0.09
147
1157
18
79
2.29
2.68
1.8
2.2
642.85
620.86
e6/l
0.04
13
70
49
305
1.63
2.64
3.1
5.0
2.59
2.54
mmol/l
0.05
33
211
481
4242
1.19
2.61
3.6
3.2
—
—
—
0
0
191
1528
1.28
2.60
4.3
3.7
1.83
1.83
mmol/l
0.01
169
1311
69
468
1.50
2.57
3.1
3.4
1.50
1.61
mg/l
0.50
63
427
367
3165
1.21
2.53
5.7
5.0
—
—
—
0
0
42
254
1.67
2.53
1.5
1.4
—
10.40
u/ml
—
0
6
1390
13451
1.27
2.52
6.3
6.0
2.61
2.67
mmol/l
1.75
1310
12485
147
1146
1.31
2.44
4.2
4.0
—
—
—
0
0
13
51
2.56
2.44
3.7
2.8
0.61
0.60
mmol/l
0.20
13
51
1364
13182
1.25
2.43
5.4
5.2
1.40
1.44
mmol/l
2.71
1282
12199
283
2395
1.22
2.36
1.3
1.3
12.05
11.74
u/ml
0.03
91
916
1370
13259
1.24
2.32
5.5
5.3
4.50
4.58
mmol/l
2.17
1296
12352
149
1173
1.30
2.32
3.6
3.9
1.23
1.23
mmol/l
0.49
134
1009
75
531
1.43
2.28
3.8
3.8
39.44
93.50
mg/l
1.04
61
452
201
1646
1.25
2.28
1.3
1.4
—
—
—
0
0
121
929
1.33
2.26
1.2
1.3
—
—
—
0
0
119
913
1.33
2.23
1.5
1.3
125.61
236.88
u/ml
2.03
113
843
31
180
1.74
2.19
1.1
1.1
4.32
2.96
u/ml
0.27
21
95
174
1410
1.26
2.16
6.7
7.8
10.56
9.97
mmol/l
0.44
167
1364
134
1053
1.30
2.13
1.2
1.2
—
—
—
0
0
37
228
1.64
2.12
1.1
1.1
33.33
20.95
au/ml
0.29
11
58
23
123
1.88
2.12
1.5
1.7
393.65
325.04
mu/l
0.33
17
98
74
531
1.41
2.11
3.9
3.7
45.93
59.22
mg/l
0.50
60
451
564
5115
1.16
2.10
3.6
3.5
7.26
7.70
mmol/l
1.63
483
4356
63
440
1.45
2.08
1.5
1.5
261.51
277.90
ug/g
0.26
47
261
9
31
2.91
2.07
1.3
1.1
—
—
—
0
0
472
4227
1.17
2.07
1.8
1.7
20.17
20.13
nmol/l
0.02
420
3576
7
20
3.51
2.05
1.3
1.0
—
—
—
0
0
7
20
3.51
2.05
1.3
1.0
—
—
—
0
0
7
20
3.51
2.05
1.3
1.0
—
—
—
0
0
47
310
1.53
2.05
1.3
1.2
57.68
53.83
u/ml
—
5
29
631
5779
1.15
2.04
2.1
2.0
1.40
1.37
mmol/l
0.41
527
4844
166
1350
1.26
2.02
2.1
2.1
0.06
0.02
estimate
0.30
32
269
51
344
1.50
2.01
1.6
2.0
2.49
21.68
iu/l
0.57
21
134
26
148
1.77
1.99
1.0
1.0
0.03
0.44
u/ml
1.42
12
53
29
171
1.71
1.97
1.2
1.3
—
—
nmol/l
—
0
0
24
134
1.80
1.96
2.7
3.7
12.79
11.65
index
0.36
14
81
94
712
1.34
1.95
2.5
2.3
—
—
—
0
0
177
1457
1.24
1.94
2.4
2.3
0.22
0.21
g/l
1.83
170
1359
35
219
1.61
1.92
2.2
2.5
—
—
—
0
0
13
58
2.25
1.91
1.0
1.4
165.31
166.79
mmol/24h
0.02
13
58
7
22
3.19
1.88
1.3
1.5
—
—
—
0
0
148
1200
1.26
1.86
1.5
1.4
—
—
—
0
0
141
1138
1.26
1.84
4.4
4.0
92.55
93.53
ng/l
0.04
124
1000
66
477
1.40
1.84
3.6
3.5
2.72
3.96
ratio
0.35
27
274
28
168
1.68
1.81
1.0
1.1
3.41
4.92
u/ml
0.35
18
79
60
429
1.41
1.79
1.1
1.2
52.86
100.75
titre
—
7
40
140
1714
0.80
1.78
5.0
5.0
31.31
32.20
%
0.43
102
1127
284
2470
1.18
1.78
1.9
1.7
1117.54
1178.01
nmol/l
0.56
228
1868
94
724
1.32
1.77
2.1
1.8
1.70
1.56
g/l
0.67
78
640
227
1938
1.20
1.75
1.5
1.3
492.36
500.05
titre
0.02
55
421
22
125
1.77
1.72
1.3
1.1
134.00
151.05
titre
—
5
19
39
258
1.52
1.72
2.8
3.3
4.07
4.36
e9/l
0.33
39
258
52
367
1.43
1.68
1.3
1.4
9.89
8.83
u/l
0.21
42
293
8
31
2.59
1.66
1.0
1.2
—
—
—
0
0
15
76
1.98
1.64
2.1
3.1
1064.27
1283.76
u/ml
0.18
15
76
1301
12624
1.17
1.63
4.5
4.4
1.37
1.30
mmol/l
2.22
1204
11584
49
346
1.43
1.59
2.7
4.2
—
—
—
0
0
21
121
1.75
1.58
1.4
1.5
—
—
—
0
0
347
3095
1.16
1.58
1.3
1.3
0.92
1.65
u/ml
1.49
84
839
608
5630
1.13
1.58
4.5
4.0
136.12
76.77
ng/l
0.25
433
4144
527
4837
1.13
1.58
3.7
3.6
40.71
50.73
mg/l
0.61
343
3154
159
1328
1.22
1.55
5.1
4.7
0.92
0.90
%
0.03
58
428
153
1273
1.22
1.55
4.4
4.5
0.80
0.72
%
0.13
55
404
37
249
1.50
1.53
1.1
1.1
—
—
—
0
0
7
27
2.60
1.51
1.6
1.9
—
—
—
0
0
43
300
1.45
1.50
1.4
1.4
—
—
—
0
0
40
276
1.46
1.48
1.4
1.4
154.08
161.49
au/ml
—
9
77
427
3882
1.14
1.47
1.4
1.4
—
—
—
0
0
76
588
1.31
1.43
1.8
1.8
4.99
7.27
iu/ml
0.52
15
131
120
983
1.24
1.43
3.3
3.3
128.34
128.86
g/l
0.09
114
961
18
103
1.76
1.41
1.7
1.1
104.17
103.51
pmol/l
0.02
18
103
289
2568
1.15
1.39
1.4
1.3
23.13
30.96
iu/ml
1.20
80
806
150
1262
1.21
1.38
5.2
4.7
0.08
0.12
%
0.44
51
361
54
399
1.37
1.38
1.4
1.2
1.82
2.34
u/ml
—
5
33
30
199
1.52
1.35
1.7
1.3
244.36
76.84
mu/l
0.44
25
182
54
402
1.36
1.33
1.4
1.2
16.27
10.53
u/ml
—
6
56
47
342
1.39
1.33
1.2
1.1
0.67
6.74
eliau/ml
1.15
11
34
60
461
1.31
1.22
1.1
1.1
—
—
—
0
0
35
246
1.43
1.21
1.0
1.1
—
—
—
0
0
5
19
2.64
1.21
2.0
1.5
—
—
—
0
0
44
324
1.37
1.18
2.7
3.2
58.30
58.43
%
0.03
44
324
16
94
1.71
1.17
2.4
2.9
34.78
39.85
%
—
9
49
16
94
1.71
1.17
1.1
1.1
11.72
16.60
u/ml
—
8
41
69
544
1.28
1.17
2.2
2.0
20.74
21.01
s
0.20
57
496
28
190
1.48
1.16
1.3
1.2
—
—
—
0
0
48
360
1.34
1.16
1.9
2.3
130.31
129.67
g/l
0.07
35
294
29
199
1.47
1.15
1.6
1.7
—
—
—
0
0
51
387
1.33
1.14
1.5
1.6
30751.31
14767.14
e6/l
0.64
26
270
106
883
1.21
1.12
1.1
1.2
69.99
139.16
u/ml
2.55
42
345
25
168
1.50
1.10
1.6
1.5
—
—
—
0
0
54
417
1.31
1.08
1.1
1.1
—
—
—
0
0
7
32
2.19
1.08
2.0
2.1
3.22
3.50
mmol/l
—
7
26
528
4940
1.10
1.07
4.5
4.3
6.79
9.23
mg/mmol
0.92
337
3138
7
33
2.13
1.05
4.4
6.6
4.60
5.24
kpa
—
7
33
24
162
1.49
1.04
1.7
1.6
79.63
61.03
%
2.19
16
108
22
146
1.51
1.03
1.0
1.2
—
—
—
0
0
41
307
1.34
1.02
1.4
3.4
—
—
—
0
0
28
196
1.44
1.02
1.3
3.1
—
—
—
0
0
147
1276
1.17
1.00
5.2
5.0
0.06
0.13
%
0.61
48
335
26
181
1.44
0.98
1.2
1.3
—
—
—
0
0
0
30
0.00
0.97
0.0
3.4
—
5.70
—
0
30
24
166
1.45
0.94
1.6
2.3
—
—
—
0
0
7
37
1.90
0.94
1.0
2.6
—
—
—
0
0
40
305
1.32
0.91
1.2
1.9
0.92
0.85
nmol/l
0.31
33
259
43
332
1.30
0.90
1.4
1.4
28.07
57.29
e6/l
0.46
29
242
356
3302
1.10
0.86
5.1
4.0
1.02
1.47
kg/l
0.50
237
2217
25
178
1.41
0.86
1.2
1.1
1.22
2.20
eliau/ml
1.32
15
73
11
64
1.72
0.86
1.0
1.2
154.36
220.69
iu/ml
0.54
11
64
72
598
1.21
0.83
2.2
2.7
—
—
—
0
0
11
178
0.62
0.83
1.2
2.0
—
2306.67
—
0
6
43
337
1.28
0.82
1.4
1.4
18048.65
720.05
e6/l
0.53
31
258
69
572
1.22
0.82
1.9
2.3
766.51
419.98
ug/l
0.39
62
548
10
164
0.61
0.80
1.4
1.1
—
—
—
0
0
35
452
0.77
0.79
1.1
1.2
1.50
1.52
g/l
0.14
35
452
162
1446
1.13
0.79
1.6
1.6
—
—
—
0
0
97
1121
0.86
0.77
1.4
1.4
—
—
—
0
0
9
54
1.67
0.74
2.4
1.9
122.44
53.81
ug/l
—
9
54
109
953
1.15
0.73
6.8
7.6
24.90
24.46
mmol/l
0.69
103
912
55
453
1.22
0.72
1.3
2.1
—
—
—
0
0
46
372
1.24
0.71
1.1
1.1
—
—
—
0
0
16
109
1.47
0.71
1.3
1.1
—
—
—
0
0
55
454
1.22
0.70
1.3
2.1
—
—
—
0
0
196
1786
1.11
0.69
3.9
3.4
4.16
4.95
e9/l
1.28
181
1555
12
77
1.56
0.68
1.2
1.7
—
—
—
0
0
55
456
1.21
0.68
1.3
2.1
—
—
—
0
0
98
856
1.15
0.67
3.1
2.9
1.20
1.20
%
0.00
98
851
15
102
1.48
0.67
1.3
1.1
—
—
—
0
0
17
119
1.43
0.67
1.8
1.4
21.17
29.50
%
0.53
12
74
58
690
0.83
0.66
1.9
2.2
0.00
1.24
estimate
0.51
27
205
435
4119
1.08
0.66
5.0
4.1
0.00
0.00
estimate
0.96
166
1450
19
137
1.39
0.64
1.0
1.1
—
—
—
0
0
10
154
0.65
0.64
1.4
1.1
—
—
—
0
0
44
359
1.23
0.64
1.4
2.3
—
—
—
0
0
38
305
1.25
0.64
1.4
1.4
—
—
—
0
0
33
414
0.79
0.63
1.1
1.1
0.69
0.68
ratio
—
7
54
39
315
1.24
0.62
6.1
8.8
103.59
105.46
mmol/l
1.16
34
285
39
315
1.24
0.62
6.1
8.8
12.18
11.30
mmol/l
0.38
34
285
15
104
1.45
0.62
1.1
1.5
1.09
1.18
promille
—
10
85
81
703
1.16
0.62
4.2
3.6
1.02
1.02
ratio
0.64
72
652
11
71
1.55
0.62
1.3
1.6
—
—
—
0
0
19
139
1.37
0.60
4.4
2.5
873.79
1071.76
mg
0.22
19
139
8
51
1.57
0.60
2.0
1.3
—
—
—
0
0
8
51
1.57
0.60
1.0
1.1
—
—
—
0
0
54
454
1.20
0.60
1.4
2.1
—
—
—
0
0
17
122
1.40
0.60
1.1
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
3.35
—
0
17
14
97
1.45
0.59
1.6
2.8
16.04
16.26
%
0.07
14
97
29
228
1.28
0.58
2.5
2.2
1.02
0.90
%
0.48
21
164
6
35
1.72
0.57
1.0
1.4
25.83
27.94
s
—
6
35
21
158
1.33
0.57
1.6
1.6
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
241.67
289.61
pmol/l
—
6
23
550
5285
1.06
0.54
5.6
5.4
2.27
2.62
ug/l
0.59
495
4778
50
423
1.19
0.53
1.3
2.2
—
—
—
0
0
17
125
1.36
0.53
1.7
2.2
9.22
8.93
umol/l
0.03
11
91
9
62
1.45
0.53
1.1
1.2
12.22
9.65
mm/h
—
9
62
9
62
1.45
0.53
1.0
1.5
40.00
39.45
g/l
—
9
62
23
292
0.78
0.51
1.7
1.7
—
—
—
0
0
15
110
1.37
0.48
1.0
1.1
—
66.64
—
0
5
7
107
0.65
0.48
1.3
1.3
—
—
—
0
0
11
155
0.71
0.48
1.0
1.1
—
—
—
0
0
11
76
1.45
0.48
1.0
1.3
6.03
6.04
ug/l
0.00
11
65
578
5589
1.05
0.45
4.7
3.9
0.01
0.10
estimate
0.57
152
1317
24
192
1.25
0.45
1.3
1.2
—
—
—
0
0
16
206
0.77
0.41
1.9
2.2
—
9.60
—
0
5
11
150
0.73
0.41
3.2
2.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
173.20
—
0
5
0
16
0.00
0.41
0.0
1.3
—
48.56
—
0
16
0
16
0.00
0.41
0.0
2.6
—
0.66
—
0
16
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
0.02
—
0
17
0
17
0.00
0.40
0.0
4.6
—
34.41
—
0
17
0
18
0.00
0.40
0.0
1.4
—
6.24
—
0
11
78
702
1.12
0.40
4.7
5.8
1.71
1.59
%
0.37
71
665
48
419
1.15
0.39
4.2
4.3
3.83
3.92
mmol/l
0.70
48
414
49
430
1.14
0.37
1.1
1.3
—
—
—
0
0
40
346
1.16
0.37
1.7
2.3
114.44
107.32
ug/min
0.05
18
207
21
171
1.23
0.35
1.4
1.2
—
—
—
0
0
20
162
1.24
0.35
1.6
1.9
—
—
—
0
0
107
987
1.09
0.35
1.8
1.7
—
—
—
0
0
14
109
1.29
0.33
1.0
1.1
—
—
—
0
0
45
397
1.14
0.33
1.9
1.9
206.69
213.89
pmol/l
0.16
45
377
40
350
1.15
0.33
1.6
1.6
—
—
—
0
0
6
88
0.68
0.33
2.2
2.3
1.00
1.89
ug/l
—
6
75
6
90
0.67
0.32
2.2
2.3
2.33
3.10
ug/l
—
6
85
19
155
1.23
0.32
1.1
1.2
—
—
—
0
0
6
47
1.28
0.32
1.3
1.1
—
—
—
0
0
71
646
1.10
0.32
1.5
1.7
0.24
0.35
mg/l
1.80
37
312
289
3010
0.95
0.32
1.8
1.8
55284999.88
31979513.81
pmol/l
0.25
246
2486
26
305
0.85
0.31
1.4
1.3
—
—
—
0
0
7
97
0.72
0.31
1.3
1.8
54.23
105.70
ng/l
—
7
97
34
296
1.15
0.30
1.1
1.2
182.65
268.31
u/ml
1.20
16
172
10
75
1.34
0.30
2.3
1.9
—
48.30
—
0
5
42
472
0.89
0.29
1.5
1.2
0.92
0.91
g/l
0.11
42
472
70
642
1.09
0.28
5.0
6.1
0.86
0.87
%
0.10
64
606
12
94
1.28
0.28
1.3
1.5
153.59
158.92
pmol/l
0.07
12
94
40
356
1.13
0.27
2.6
3.2
30.38
34.59
umol/l
0.79
34
318
20
169
1.19
0.26
1.5
1.6
—
—
—
0
0
504
5160
0.97
0.25
3.2
3.3
—
—
—
0
0
117
1103
1.07
0.25
2.8
2.6
6.03
6.09
ph
0.40
92
758
15
124
1.21
0.24
1.0
1.1
—
—
titre
—
0
0
28
246
1.14
0.23
1.1
1.1
—
—
—
0
0
28
246
1.14
0.23
1.1
1.1
—
—
—
0
0
14
115
1.22
0.23
1.9
2.0
48.56
39.45
%
1.11
14
115
5
38
1.32
0.23
1.0
1.1
47.80
35.33
nmol/l
—
5
29
5
39
1.28
0.23
1.2
1.1
—
880.00
—
0
10
11
88
1.25
0.22
1.6
1.3
1.57
1.20
nmol/l
0.62
11
64
7
95
0.74
0.22
2.4
1.6
—
—
—
0
0
325
3160
1.04
0.21
3.1
3.2
0.83
0.75
ug/l
0.71
215
2044
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
81.30
—
0
10
31
346
0.89
0.21
6.7
4.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
71
664
1.07
0.20
2.2
2.0
5.35
1.90
ug/l
0.67
65
589
23
261
0.88
0.20
1.3
1.4
264.35
275.77
pmol/l
0.02
23
256
34
307
1.11
0.20
2.6
3.4
0.84
0.83
nmol/l
0.08
28
254
6
49
1.23
0.20
1.8
1.8
166.70
91.00
nmol/24h
—
6
49
129
1350
0.95
0.19
4.5
4.5
7.35
7.36
ph
0.03
101
992
19
165
1.15
0.19
1.7
1.4
—
—
—
0
0
129
1348
0.95
0.19
1.9
2.1
3.60
3.55
ratio
0.16
103
1084
74
696
1.07
0.18
1.3
1.2
—
—
—
0
0
22
194
1.14
0.18
1.6
1.5
—
—
—
0
0
22
194
1.14
0.18
1.6
1.5
—
—
—
0
0
22
194
1.14
0.18
1.6
1.5
—
—
—
0
0
22
194
1.14
0.18
1.6
1.5
—
—
—
0
0
65
693
0.94
0.18
4.7
3.8
—
—
—
0
0
119
1243
0.95
0.17
3.0
2.5
0.40
0.44
e6/l
0.09
113
1185
17
194
0.87
0.16
1.1
1.2
—
—
—
0
0
8
69
1.16
0.16
18.9
13.3
0.60
0.63
mmol/l
—
8
64
12
141
0.85
0.16
1.2
1.3
5824.60
171521.35
e6/l
—
5
94
10
84
1.19
0.14
1.0
1.2
—
—
—
0
0
95
990
0.96
0.14
1.6
1.8
3.55
3.47
mmol/l
0.22
65
723
8
100
0.80
0.13
2.3
1.1
40.50
35.19
mmol/l
—
8
93
9
109
0.82
0.13
1.1
1.1
450.33
378.81
nmol/l
—
9
94
12
104
1.16
0.12
1.3
2.5
7.79
7.99
mmol/l
0.05
12
104
32
298
1.08
0.11
1.9
2.2
2897.60
5476.56
u/l
0.45
11
122
31
331
0.94
0.10
1.4
1.6
766.44
930.87
mu/l
0.95
23
276
69
663
1.04
0.10
1.9
2.0
—
—
—
0
0
14
156
0.90
0.10
1.3
1.6
—
—
—
0
0
5
45
1.11
0.09
7.8
4.5
—
—
—
0
0
40
422
0.95
0.09
18.1
11.0
—
—
—
0
0
5
48
1.04
0.09
2.2
1.7
0.00
0.06
estimate
—
5
48
39
370
1.06
0.09
1.5
1.3
212.89
237.95
miu/ml
0.17
18
165
21
194
1.08
0.09
1.7
2.4
0.25
1.29
g/24h
—
9
117
97
998
0.97
0.08
4.2
3.7
7.41
7.42
ph
0.10
82
849
16
175
0.91
0.08
1.7
1.5
—
—
—
0
0
5
64
0.78
0.08
1.4
1.2
—
—
—
0
0
52
541
0.96
0.08
4.4
4.0
24.64
24.87
mmol/l
0.23
47
505
7
66
1.06
0.08
1.3
1.1
—
—
—
0
0
16
147
1.09
0.07
1.2
1.2
—
—
—
0
0
9
85
1.06
0.07
1.8
1.2
126.33
143.45
nmol/l
—
9
85
9
102
0.88
0.06
1.4
1.4
77.22
84.22
umol/l
—
9
102
21
197
1.07
0.06
1.6
1.4
744.08
1601.01
e6/l
2.51
12
133
32
335
0.95
0.06
1.1
1.3
—
—
—
0
0
58
598
0.97
0.06
3.8
3.4
10834.09
2642.69
u/ml
0.34
49
514
159
1566
1.02
0.05
4.1
4.4
55.96
20.90
ug/l
0.32
130
1289
18
169
1.07
0.05
1.2
1.4
0.27
0.32
nmol/l
0.28
11
129
14
150
0.93
0.04
1.3
1.5
—
—
—
0
0
18
170
1.06
0.04
1.7
1.4
44158.57
113550.24
e6/l
—
7
92
20
210
0.95
0.03
1.3
1.2
2.00
5.66
u/ml
—
9
96
15
141
1.06
0.03
2.4
2.5
—
—
—
0
0
14
148
0.95
0.02
1.2
1.5
1.37
1.29
mm
—
8
106
15
143
1.05
0.01
1.4
2.2
—
—
—
0
0
14
147
0.95
0.01
2.1
2.3
—
—
—
0
0
52
528
0.98
0.01
1.9
3.7
245.52
301.74
mg/l
0.36
21
232
11
104
1.06
0.01
1.3
1.4
3.01
2.67
ug/l
0.23
11
86
398
3986
1.00
0.00
3.7
3.4
0.17
0.24
estimate
0.10
149
1248
15
148
1.01
0.00
2.7
4.5
—
—
—
0
0
11
111
0.99
0.00
1.7
2.4
595.83
605.68
ml
—
6
71
20
197
1.02
0.00
1.3
1.6
86.82
60.54
ug/l
0.75
15
163
59
593
0.99
0.00
1.4
1.7
—
—
—
0
0
5
59
0.85
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
421.13
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
34.26
—
0
5
9
99
0.91
-0.00
1.0
1.6
14.90
13.02
umol/l
—
9
94
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.5
3.02
2.56
%
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
171.83
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
0.16
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
52.27
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.5
2.80
3.31
mmol/l
—
5
46
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
15
150
1.00
-0.00
1.1
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_EAR_NASAL_SINUS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_EAR_NASAL_SINUS 1.289 [1.13, 1.47] < 0.001
Birth year 0.995 [0.99, 1.0] 0.221

During the follow-up period (1.1.1998 — 31.12.2019), 531 out of 3276 females with CD2_BENIGN_EAR_NASAL_SINUS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_EAR_NASAL_SINUS 1.197 [0.99, 1.44] 0.058
Birth year 0.989 [0.94, 1.04] 0.691

During the follow-up period (1.1.1998 — 31.12.2019), 689 out of 3623 males with CD2_BENIGN_EAR_NASAL_SINUS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_EAR_NASAL_SINUS.

N-year risk Females Males
1 0.15% 0.216%
5 0.85% 1.352%
10 2.003% 3.63%
15 3.69% 6.902%
20 6.21% 11.55%

Relationships between endpoints

Index endpoint: CD2_BENIGN_EAR_NASAL_SINUS – Benign neoplasm: Middle ear, nasal cavity and accessory sinuses

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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