Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3006804	li-cnab	— (—)	242	248	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Symptoms and signs involving the nervous and musculoskeletal systems

100

8.82

70.63

1.0

—

Other symptoms and signs involving the nervous and musculoskeletal systems

8.51

48.45

1.0

—

Polyneuropathies and other disorders of the peripheral nervous system

10.49

42.82

1.0

—

Epilepsy

9.61

41.92

1.0

—

Other and unspecified polyneuropathies, also in other diseases

10.82

39.06

1.0

1.1

—

Focal epilepsy, strict definition

11.92

37.62

1.0

1.1

—

Focal epilepsy

10.57

35.71

1.0

1.1

—

Other symptoms and signs involving cognitive functions and awareness

7.29

34.80

1.0

—

Focal epilepsy, mode (most common among epilepsy diagnosis)

11.29

34.42

1.0

1.1

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

138

4.52

32.86

1.0

—

Inflammatory diseases of the central nervous system

15.40

29.67

1.0

1.1

—

Neurological diseases

7.00

27.12

1.0

—

Concussion

8.14

21.92

1.0

—

Intracranial trauma

7.48

20.37

1.0

—

Other encephalitis

39.20

18.61

1.0

—

Encephalitis

39.14

18.60

1.0

—

Other medical care

4.89

18.32

1.0

—

Convulsions, not elsewhere classified

7.35

17.92

1.0

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

131

3.82

17.86

1.0

—

Anaemias

13.98

17.72

1.0

—

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

14.62

17.62

1.0

—

Abnormalities of gait and mobility

10.04

17.59

1.0

—

Malaise and fatigue

4.67

17.32

1.1

1.0

—

Any gastric operation

4.92

17.30

1.0

—

GASTRO-related operations

4.92

17.30

1.0

—

General symptoms and signs

105

3.44

16.68

1.1

1.0

—

Bacterial infection, other or unspecified

101

4.11

16.66

1.0

—

Other degenerative diseases of the nervous system

10.84

16.00

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion

112

3.38

15.44

1.1

1.0

—

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

112

3.38

15.44

1.1

1.0

—

Malignant neoplasm

116

3.33

15.34

1.1

1.0

—

Systemic atrophies primarily affecting the central nervous system

12.62

15.15

1.1

1.0

—

Hypothyroidism (congenital or acquired)

12.08

15.04

1.0

—

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

112

3.33

14.87

1.1

1.0

—

Primary_lymphoid and hematopoietic malignant neoplasms

5.79

14.42

1.0

—

Abnormal findings on diagnostic imaging of central nervous system

27.42

14.28

1.1

1.0

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

166

2.94

14.03

1.0

—

General examination and investigation of persons without complaint and reported diagnosis

3.67

13.31

1.0

—

Primary_lymphoid and hematopoietic malignant neoplasms

5.32

13.22

1.0

—

Viral infections of the central nervous system

10.05

13.13

1.0

—

Fever of other and unknown origin

4.07

13.05

1.1

1.0

—

Hypothyroidism and >3 levothyroxin purchases

10.94

12.95

1.0

—

Hypothyroidism, levothyroxine purchases

10.94

12.95

1.0

—

Other neurological diseases

134

3.18

12.92

1.0

—

Other bacterial diseases

157

2.86

12.74

1.0

—

Persons encountering health services for specific procedures and health care

152

2.81

12.69

1.0

—

Any reimbursement code in KELA

4.88

12.67

1.1

1.0

—

Dizziness and giddiness

117

3.33

12.62

1.0

—

Status epilepticus

26.94

12.05

1.0

—

Any event in cancer register

126

2.92

12.02

1.0

—

Neurological diseases, wide definition

10.05

11.97

1.0

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

8.78

11.66

1.0

—

Neoplasms

3.50

11.59

1.1

1.0

—

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

4.19

11.11

1.1

1.0

—

Non-follicular lymphoma, hilmo, excluding all cancers

8.78

11.11

1.0

—

Malignant neoplasm of eye, brain and central nervous system

10.98

11.07

1.0

—

Episodal and paroxysmal disorders

120

2.78

11.05

1.0

—

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

6.82

11.01

1.0

—

Implicit Sepsis

134

2.96

10.99

1.0

—

Condition for Implicit Sepsis (Organ dysfunction codes)

147

2.77

10.56

1.0

—

First line medication for Crohn's disease

140

2.61

10.43

1.0

—

Symptoms and signs involving the skin and subcutaneous tissue

165

2.84

10.01

1.0

—

Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)

20.13

9.80

1.0

—

Non-follicular lymphoma

7.39

9.70

1.0

1.1

—

Extrapyramidal and movement disorders

3.62

9.51

1.0

—

Delirium, not induced by alcohol and other psychoactive substances

7.01

9.26

1.1

—

Oxycodone

3.54

9.15

1.1

1.0

—

Enlarged lymph nodes

6.26

8.98

1.0

—

Implicit viral Sepsis

5.49

8.96

1.1

1.0

—

Viral Sepsis

5.49

8.96

1.1

1.0

—

Oral corticosteroids

167

2.39

8.96

1.0

—

Cardiovascular diseases (excluding rheumatic etc)

3.17

8.85

1.1

1.0

—

Speech disturbances, not elsewhere classified

7.25

8.84

1.0

1.1

—

Visual disturbances and blindness

114

3.07

8.63

1.1

1.0

—

ILD medications: prednisolone, methylprednisolone, prednisone

161

2.35

8.62

1.0

—

Inflammatory bowel disease treatment related agents

167

2.31

8.47

1.0

—

Headache

3.11

8.45

1.1

1.0

—

Dysphagia

4.16

8.44

1.0

—

Anxiety disorders, excluding more controls

123

2.64

8.35

1.1

1.0

—

Anxiety disorders

151

2.49

8.18

1.1

1.0

—

Other anxiety disorders

3.33

8.18

1.1

1.0

—

Parasetamol

2.79

8.15

1.0

—

Malignant neoplasm of brain

17.29

8.08

1.0

—

Certain infectious and parasitic diseases

108

2.55

8.06

1.0

—

Benzodiazepine use

179

2.35

8.06

1.1

1.0

—

Bacterial Sepsis

3.26

7.92

1.0

—

Medical observation and evaluation for suspected diseases and conditions

2.91

7.83

1.0

—

Care involving use of rehabilitation procedures

131

2.76

7.68

1.0

—

Cardiovascular diseases

3.11

7.65

1.0

—

Other diseases of urinary system

138

2.37

7.60

1.0

—

Visual disturbances

108

2.97

7.47

1.1

1.0

—

Abnormal involuntary movements

5.92

7.37

1.0

—

Implicit bacterial Sepsis

3.30

7.36

1.0

—

Psychiatric diseases

133

2.30

7.27

1.0

—

Other extrapyramidal and movement disorders in other diseases

4.14

7.26

1.1

1.0

—

Renal tubulo-interstitial diseases

161

2.38

7.23

1.1

1.0

—

Neurotic, stress-related and somatoform disorders

153

2.37

7.17

1.1

1.0

—

Depression medications

6.86

7.11

1.0

—

Symptoms and signs concerning food and fluid intake

7.70

7.11

1.0

—

Non-invasive ventilation

4.44

6.96

1.0

—

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

5.43

6.76

1.0

—

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

3.79

6.75

1.0

—

Tramadol

125

2.42

6.74

1.0

—

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

3.40

6.72

1.1

1.0

—

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

3.40

6.72

1.1

1.0

—

Symptoms and signs involving speech and voice

3.29

6.67

1.0

—

ILD medications

161

2.15

6.65

1.0

—

Fall on same level

165

2.13

6.57

1.0

—

Mood disorders, excluding more controls

139

2.28

6.47

1.0

—

Other antidepressants

131

2.23

6.38

1.0

—

Hypertensive diseases (excluding secondary)

2.86

6.32

1.1

1.0

—

Disorders of thyroid, IBD co-morbidities

13.38

6.32

1.1

1.0

—

Organic, including symptomatic, mental disorders

2.74

6.24

1.0

—

Benign neoplasm: Skin of eyelid, including canthus

5.01

6.22

1.0

—

ILD medications: azathioprine

5.01

6.22

1.0

1.1

—

Malignant melanoma, excluding all cancers (controls excluding all cancers)

5.01

6.22

1.0

—

Intracranial injury

116

2.67

6.17

1.0

—

Anxiety (asthma-related co-morbidities)

106

2.60

6.16

1.1

1.0

—

ILD medications: immunosuppressive drugs

139

2.48

6.03

1.0

—

All anxiety disorders

110

2.56

6.01

1.1

1.0

—

Other mental disorders due to brain damage and dysfunction and to physical disease

5.23

6.00

1.0

1.1

—

Spondylolisthesis/Spondylolysis

4.52

5.97

1.0

—

Symptoms and signs involving the urinary system

143

2.33

5.97

1.0

—

Diplopia

4.82

5.97

1.2

1.0

—

Azathioprine

4.82

5.97

1.0

1.1

—

Influenza and pneumonia

179

2.09

5.96

1.0

—

Cystitis

122

2.31

5.92

1.0

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

2.92

5.92

1.0

—

Depression or dysthymia

2.59

5.88

1.0

—

Used for control exclusion in common control thyroid runs

126

2.17

5.78

1.1

1.0

—

Other soft tissue disorders, not elsewhere classified

137

2.21

5.76

1.0

—

Other and unspecified anaemias

2.86

5.72

1.0

—

Certain disorders involving the immune mechanism

3.91

5.70

1.1

1.0

—

All pneumoniae

183

2.07

5.70

1.0

—

Other disorders of urethra and urinary system

114

2.43

5.64

1.1

1.0

—

Other anaemias

2.82

5.58

1.0

—

Other diseases of hard tissues of teeth

114

2.42

5.58

1.1

1.0

—

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

3.81

5.53

1.1

1.0

—

Injuries to the head

183

2.03

5.51

1.0

—

Diseases of the myoneural junction and muscle

4.49

5.50

1.2

1.0

—

Symptoms and signs involving the digestive system and abdomen

134

2.09

5.49

1.1

1.0

—

L02BG Aromatase inhibitors

3.23

5.43

1.1

1.0

—

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

181

2.06

5.42

1.0

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

16.08

5.41

1.0

—

Any mental disorder

142

2.05

5.36

1.0

—

Zoster [herpes zoster]

4.12

5.35

1.0

1.1

—

Pneumonias (Asthma/COPD co-morbidities)

184

2.03

5.34

1.0

—

Dorsopathies

132

2.09

5.29

1.0

—

Pneumonia, organism unspecified

174

2.08

5.29

1.0

—

Panic disorder

4.62

5.25

1.1

—

Factors influencing health status and contact with health services

3.82

5.23

1.1

1.0

—

Malignant neoplasm of breast

2.65

5.21

1.1

1.0

—

Autoimmune diseases

140

2.04

5.20

1.1

1.0

—

Spondylopathies

117

2.23

5.19

1.0

—

Vocal cord dysfunction

4.65

5.17

1.0

—

Selective serotonin reuptake inhibitors

131

2.09

5.16

1.1

1.0

—

138

2.13

5.15

1.0

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

138

2.13

5.15

1.0

—

Medicines for HER+ breast cancer

2.88

5.14

1.0

—

Depression

167

2.06

5.13

1.0

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

151

2.10

5.11

1.0

—

Other lack of coordination

13.49

5.09

1.1

1.0

—

Viral encephalitis, not elsewhere classified/unspecified

13.46

5.09

1.0

—

Paraplegia, diplegia of upper limbs

13.45

5.08

1.0

—

Autoimmune diseases excluding thyroid diseases

140

2.06

5.07

1.1

1.0

—

Pain, not elsewhere classified

3.56

5.03

1.1

1.0

—

Other diseases of blood and blood-forming organs, wide

3.40

5.02

1.0

—

Venous thromboembolism

124

2.43

5.01

1.0

—

Persons encountering health services in other circumstances, wide

163

1.94

4.99

1.0

—

Endocrine, nutritional and metabolic diseases

101

2.22

4.99

1.0

—

Mood [affective] disorders

175

1.99

4.94

1.0

—

Mood disorders

175

1.99

4.92

1.0

—

Systemic connective tissue disorders

2.86

4.91

1.1

1.0

—

Disturbances of skin sensation

3.12

4.90

1.0

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

162

1.97

4.90

1.1

1.0

—

Autoimmune diseases excluding thyroid diseases, strict definition

132

2.07

4.84

1.1

1.0

—

Hypothyroidism, strict autoimmune

103

2.31

4.84

1.0

—

Benign neoplasms

2.39

4.81

1.0

—

Abnormal weight loss

5.01

4.77

1.0

1.1

—

Abnormal findings on diagnostic imaging of lung

104

2.53

4.77

1.0

—

Aplastic and other anaemias

2.57

4.71

1.0

—

Hypothyroidism, other/unspecified

143

2.08

4.70

1.0

—

Soft tissue disorders

138

2.00

4.69

1.1

1.0

—

Dorsalgia

130

2.04

4.66

1.0

—

Diffuse large B-cell lymphoma, helper endpoint

14.05

4.58

1.0

—

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

14.05

4.58

1.0

—

Stroke, excluding SAH

106

2.31

4.57

1.0

—

Other dorsopathies, not elsewhere classified

131

2.01

4.56

1.0

—

Restless leg syndrome

4.41

4.56

1.1

1.0

—

Weight loss

4.77

4.53

1.0

—

Benign neoplasm: Skin of eyelid, including canthus

3.83

4.53

1.0

1.1

—

Other symptoms and signs involving the digestive system and abdomen

3.83

4.53

1.0

—

Malignant neoplasm of breast, HER-positive

2.80

4.52

1.0

—

Acute tubulo-interstitial nephritis

124

2.29

4.50

1.1

1.0

—

Other benign neoplasms of skin

2.96

4.50

1.0

—

Hypothyroidism, drug reimbursement

11.44

4.43

1.0

—

Finngen Rheumatological endpoints

149

1.95

4.38

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

4.24

4.35

1.0

—

Hypo-osmolality and hyponatraemia

3.71

4.34

1.0

—

Malignant neoplasm of breast, HER2-negative

2.48

4.34

1.1

1.0

—

Implicit fungal Sepsis

11.72

4.28

1.1

1.0

—

Fungal Sepsis

11.72

4.28

1.1

1.0

—

Myalgia

3.42

4.18

1.0

—

Spondylosis

108

2.30

4.13

1.1

1.0

—

Speech and linguistic disorders, excluding more controls

8.39

4.11

1.0

—

Disorders of parathyroid gland

3.37

4.09

1.0

—

Other and unspecified types of non-Hodgkin lymphoma, hilmo

8.04

4.06

1.0

—

Constipation

161

1.96

4.04

1.0

—

Disorders of the thyroid gland

155

1.94

4.04

1.0

—

Opioids

130

1.94

4.00

1.0

—

Spontaneous rupture of synovium and tendon

6.44

3.98

1.0

—

Other reaction to severe stress, and adjustment disorders

2.67

3.98

1.1

1.0

—

Antihypertensive medication - note that there are other indications

2.29

3.93

1.0

—

Other disorders of fluid, electrolyte and acid-base balance

2.74

3.93

1.1

1.0

—

DVT of lower extremities and pulmonary embolism

2.42

3.92

1.0

—

Stroke, including SAH

114

2.14

3.88

1.0

—

Recurrent or chronic depression

2.80

3.83

1.0

—

L04AX Other immunosuppressants

133

2.18

3.78

1.0

—

Fitting and adjustment of other devices

2.68

3.76

1.0

—

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

2.41

3.74

1.0

—

Disorders of speech understanding and production

8.62

3.72

1.0

—

Agranulocytosis

4.01

3.69

1.0

—

Oedema, not elsewhere classified

2.90

3.69

1.0

—

Low back pain

127

2.06

3.68

1.0

—

Disorders of other endocrine glands

2.38

3.66

1.0

—

Other shoulder lesions

5.63

3.65

1.1

1.0

—

Complications of procedures, not elsewhere classified

180

1.92

3.65

1.1

1.0

—

Diseases of the eye and adnexa

100

2.00

3.63

1.1

1.0

—

Deforming dorsopathies

2.86

3.62

1.0

—

Diagnoses used for exclusion with ILD

2.86

3.62

1.0

—

Second line medication for Crohn's disease

136

2.13

3.59

1.0

—

Pulmonary heart disease

2.65

3.55

1.0

—

Pulmonary embolism

2.65

3.55

1.0

—

Dental pulpitis 2, only avohilmo

2.08

3.53

1.1

1.0

—

Dental caries 1 and operation codes

111

1.94

3.53

1.0

—

Other systemic involvement of connective tissue (FG)

2.92

3.52

1.1

1.0

—

Cerebral palsy and other paralytic syndromes

3.85

3.52

1.0

1.1

—

Continuous positive airway pressure

3.45

3.51

1.0

—

External causes of morbidity and mortality

2.12

3.46

1.1

1.0

—

COPD/asthma/ILD related infections

138

1.81

3.44

1.0

—

COPD/asthma related infections

138

1.81

3.44

1.0

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

169

1.81

3.42

1.0

—

COPD differential diagnosis

106

1.94

3.42

1.0

—

ILD differential diagnosis

106

1.94

3.42

1.0

—

Hyperparathyroidism

3.30

3.40

1.0

—

Speech and linguistic disorders

5.91

3.39

1.0

—

Excessive attrition of teeth

2.45

3.37

1.0

—

Diffuse large B-cell lymphoma

7.02

3.36

1.0

—

L04AA Selective immunosuppressants

2.83

3.35

1.1

1.0

—

Dental caries 3 and operation codes

117

1.89

3.35

1.0

—

Diseases of oral cavity, salivary glands and jaws

117

1.89

3.35

1.0

—

Disorders of vestibular function (Vertigo)

113

2.20

3.34

1.0

—

Excluding asthma or asthma-COPD overlap

107

1.92

3.34

1.0

—

Other septicaemia

2.56

3.33

1.1

1.0

—

Ischaemic Stroke, excluding all haemorrhages

104

2.11

3.33

1.0

—

Malignant melanoma

3.44

3.33

1.0

1.1

—

Cough

2.28

3.31

1.0

—

Disorders of ocular muscles, binocular movement, accommodation and refraction

101

2.26

3.28

1.1

1.0

—

Falls/tendency to fall

144

1.77

3.28

1.0

—

Complications of surgical and medical care, not elsewhere classified

190

1.77

3.28

1.1

1.0

—

Alzheimer disease, excluding more controls

7.79

3.28

1.0

—

Other special examinations and investigations of persons without complaint or reported diagnosis

2.12

3.27

1.0

—

Specific development disorders of speech and language

6.75

3.27

1.0

—

Other CVD (FINNGEN)

5.07

3.27

1.0

—

Other and unspecified degenerative diseases of nervous system

8.62

3.26

1.2

1.0

—

Other diseases of spinal cord

8.61

3.26

1.0

—

Other disorders of lacrimal gland

2.38

3.22

1.0

—

Infections with a predominantly sexual mode of transmission

2.67

3.21

1.0

1.1

—

L01XE Protein kinase inhibitors

5.35

3.19

1.0

1.1

—

Other enthesopathy of foot (+metatarsalgia)

5.34

3.19

1.1

1.0

—

Immunodeficiencies

6.38

3.18

1.0

—

Cerebral cysts

6.38

3.18

1.0

—

Complications of medical and surgical care

175

1.90

3.18

1.1

1.0

—

Dental caries, including avohilmo

1.96

3.13

1.1

1.0

—

Dental caries 1

1.96

3.13

1.1

1.0

—

STROKE

107

2.01

3.12

1.0

—

Pulmonary heart disease, diseases of pulmonary circulation

2.47

3.11

1.0

—

Lung cancer and mesothelioma

3.01

3.10

1.1

1.0

—

Subjective visual disturbances

2.80

3.08

1.0

—

Explicit Sepsis

2.34

3.08

1.1

1.0

—

Small fibre neuropathy

7.54

3.06

1.0

—

Dissociative [conversion] disorders

7.52

3.05

1.0

—

Chronic laryngitis and laryngotracheitis

3.24

3.05

1.0

—

Disorders of lacrimal system

2.22

3.05

1.0

—

Cerebrovascular diseases

137

1.88

3.04

1.0

—

3.45

3.04

1.1

1.0

—

Other disorders of eye and adnexa

3.45

3.04

1.0

1.1

—

Fibromyalgia

5.84

3.02

1.0

—

Sleep disorders (combined)

173

1.74

3.00

1.0

—

Parkinson's disease, excluding more controls

7.31

3.00

1.0

—

Attention to artificial openings

10.03

2.98

1.0

—

Hypertension, essential

121

1.84

2.94

1.1

1.0

—

Nerve, nerve root and plexus disorders

186

1.69

2.91

1.0

—

Nutritional anaemias

111

2.10

2.91

1.0

—

Hard cardiovascular diseases

143

1.80

2.88

1.1

1.0

—

Gingivitis and periodontal diseases

117

1.81

2.87

1.0

—

Septicaemia

2.31

2.87

1.1

1.0

—

Allergic asthma (mode), excluding more controls

2.95

2.87

1.0

—

Other systemic involvement of connective tissue

2.59

2.87

1.1

1.0

—

Degenerative diseases of the nervous system

2.56

2.83

1.1

1.0

—

Viral infections characterized by skin and mucous membrane lesions

2.19

2.82

1.0

—

Other and unspecified nerve root and plexus disorders, also in other diseases

3.06

2.80

1.1

1.0

—

Hypertensive diseases

122

1.81

2.80

1.1

1.0

—

Hypertension

122

1.81

2.80

1.1

1.0

—

Other pulmonary diagnosis

107

1.83

2.80

1.1

1.0

—

Thyroiditis, ILD-related definition

3.92

2.77

1.0

—

Migraine with aura

3.23

2.77

1.0

1.1

—

Allergic asthma (mode)

2.87

2.76

1.0

—

Papilloedema, unspecified

8.37

2.75

1.0

—

Other disorders of nervous system

5.01

2.73

1.0

1.1

—

Metatarsalgia

5.01

2.72

1.1

1.0

—

Disorders of psychological development

4.36

2.72

1.0

—

Visual impairment including blindness (binocular or monocular)

6.01

2.70

1.0

—

Cerebrovascular diseases (FINNGEN)

2.43

2.69

1.1

1.0

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

141

1.79

2.69

1.0

—

Disorders of synovium and tendon

112

2.01

2.68

1.0

—

Secondary hypertension

5.95

2.68

1.2

1.0

—

Dental caries 3

100

1.84

2.67

1.1

1.0

—

Cervical disc disorders

2.28

2.67

1.1

1.0

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

153

1.89

2.66

1.1

1.0

—

Diseases of inner ear

130

1.96

2.64

1.0

—

Genitourinary diseases

2.01

2.63

1.0

—

Diseases of oesophagus, stomach and duodenum

181

1.64

2.61

1.1

1.0

—

Pain in limb

136

1.81

2.59

1.0

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

141

1.91

2.58

1.1

1.0

—

Persons encountering health services for examination and investigation

1.97

2.58

1.0

—

Other bacterial intestinal infections

2.90

2.58

1.0

—

Generalized anxiety disorder

3.60

2.57

1.0

1.1

—

Drug-induced neutropenia

4.01

2.56

1.0

1.1

—

Dentofacial anomalies [including malocclusion]

2.43

2.55

1.0

—

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

2.66

2.53

1.1

1.0

—

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

2.78

2.53

1.1

1.0

—

Osteopathies and chondropathies

128

1.93

2.52

1.1

1.0

—

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

3.54

2.51

1.0

—

Atrial fibrillation and flutter with reimbursement

2.53

2.50

1.0

—

Malignant melanoma of skin

3.47

2.48

1.0

1.1

—

Other and unspecified iron deficiency

2.32

2.47

1.1

1.0

—

Other specified/unspecified bacterial intestinal infections

4.38

2.47

1.0

—

Bacterial intestinal infections, IBD co-morbidities

2.82

2.47

1.0

1.1

—

Non-selective monoamine reuptake inhibitors

2.26

2.47

1.1

1.0

—

Diabetic neuropathy

3.45

2.46

1.1

1.0

—

Problems related to lifestyle

3.81

2.46

1.0

—

Type of accident

2.38

2.45

1.1

1.0

—

Asthma (only as main-diagnosis), excluding more controls

100

1.85

2.44

1.0

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

2.24

2.43

1.1

1.0

—

Nephropathy related operations

2.95

2.41

1.1

—

Mycoses

2.35

2.38

1.1

1.0

—

Sleep apnoea

172

1.66

2.37

1.0

—

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

6.26

2.37

1.0

—

Other headache syndromes

2.21

2.37

1.0

—

Strabismus

2.41

2.35

1.1

1.0

—

Exclusions for E4_PCOS_CONSORTIUM

107

1.82

2.35

1.0

—

All influenza

2.61

2.35

1.0

—

Open wound of head

116

1.95

2.35

1.0

—

Iron deficiency anaemia

2.09

2.32

1.1

1.0

—

Other benign neoplasms of skin

2.09

2.32

1.0

—

2.05

2.31

1.1

1.0

—

Abdominal and pelvic pain

134

1.65

2.31

1.0

—

Other/unspecified dorsalgia

2.24

2.31

1.0

—

Secondary uncertain malignant neoplasm

3.22

2.30

1.0

1.1

—

Temporomandibular joint disorders

2.86

2.30

1.0

—

Osteoporosis

2.48

2.30

1.2

1.0

—

Abnormalities of breathing

147

1.66

2.27

1.0

—

Senile cataract

112

1.77

2.25

1.0

—

Visual field defects

3.89

2.25

1.0

1.1

—

Disorders of optic nerve and visual pathways

3.89

2.25

1.0

1.1

—

Leiomyoma of uterus

2.28

2.25

1.1

1.0

—

Supplementary factors related to causes of morbidity and mortality classified elsewhere

2.27

2.24

1.1

1.0

—

Retention of urine

2.18

2.23

1.1

1.0

—

Dental pulpitis 2

1.83

2.23

1.1

1.0

—

Sarcoidosis

3.11

2.22

1.0

1.1

—

Asthma (only as main-diagnosis)

105

1.78

2.21

1.0

—

Osteoporosis with pathological fracture (FG)

5.56

2.21

1.0

—

Dyspnoea

176

1.65

2.20

1.0

—

Cervicalgia

2.78

2.20

1.0

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

126

1.87

2.16

1.0

—

Any dementia, excluding more controls

2.31

2.16

1.0

—

Paralytic strabismus

4.29

2.15

1.2

1.0

—

Thyroiditis

4.29

2.15

1.0

1.1

—

Brachial plexus disorders

3.69

2.15

1.0

1.1

—

Localized swelling, mass and lump of skin and subcutaneous tissue

2.16

2.14

1.0

—

Substance abuse, excluding more controls

113

1.86

2.11

1.0

—

Other predominantly sexually transmitted diseases, not elsewhere classified

2.70

2.10

1.0

1.1

—

Glomerular disorders in diseases classified elsewhere

3.20

2.09

1.1

—

Pain associated with micturition

3.20

2.09

1.0

1.1

—

Benign neoplasm of ovary

3.20

2.09

1.0

—

Atrial fibrillation and flutter

2.22

2.09

1.0

—

Deposits [accretions] on teeth

4.14

2.08

1.0

—

Vascular syndromes of brain in cerebrovascular disorders

5.01

2.07

1.0

—

Other necrotizing vasculopathies (FG)

5.01

2.07

1.0

—

Candidiasis

2.91

2.07

1.1

—

Asthma-related infections

129

1.83

2.06

1.0

—

Asthma, hospital admission 2, infections

129

1.83

2.06

1.0

—

Other pleural conditions

3.50

2.05

1.0

1.1

—

Lower back pain or/and sciatica

195

1.57

2.04

1.0

—

Demyelinating diseases of the central nervous system

4.00

2.04

1.0

—

Paracetamol of NSAID medication

2.96

2.03

1.0

—

Diseases of the musculoskeletal system and connective tissue

1.97

2.03

1.1

1.0

—

Nausea and vomiting

2.41

2.03

1.3

1.0

—

Dermatitis

147

1.77

2.01

1.1

1.0

—

Accidents

112

1.65

2.00

1.0

—

Undefined dementia

3.94

1.99

1.0

1.1

—

Temporomandibular joint disorders, including avohilmo

2.00

1.99

1.1

1.0

—

Any dementia

2.20

1.96

1.0

—

Unspecified dementia

3.87

1.95

1.0

1.1

—

Tobacco use

4.55

1.94

1.0

—

Other enthesopathies

2.19

1.94

1.1

1.0

—

Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

4.54

1.94

1.0

1.1

—

Other condition

2.97

1.93

1.1

1.0

—

Dental caries

2.26

1.93

1.0

—

Migraine

2.04

1.93

1.0

1.1

—

Hypotension

2.73

1.93

1.0

1.1

—

Cellulitis

2.45

1.92

1.0

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

2.45

1.92

1.0

1.1

—

Dentinal caries

2.34

1.92

1.0

—

Presence of other devices

2.44

1.92

1.0

—

Dementia

2.00

1.88

1.0

—

Other acute lower respiratory infections

115

1.83

1.88

1.0

—

Other peripheral vertigo

3.19

1.88

1.0

—

Pruritus

3.19

1.88

1.1

1.0

—

Erosion of teeth, including avohilmo

2.54

1.87

1.1

1.0

—

Benign paroxysmal vertigo

2.16

1.87

1.0

—

Diarrhoea and gastroenteritis of presumed infectious origin

150

1.70

1.87

1.1

1.0

—

Gastrointestinal diseases

1.75

1.86

1.0

—

Dialysis, with operation codes

2.65

1.86

1.1

—

Non-small cell lung cancer

2.65

1.86

1.0

1.1

—

Use of hypnotics and sedatives

184

1.51

1.86

1.0

—

Diseases of pulp and periapical tissues

2.03

1.85

1.0

—

Cardiac arrhythmias

103

1.73

1.84

1.0

—

Disorders of mineral metabolism

3.53

1.83

1.0

—

Other CVD

2.50

1.83

1.0

1.1

—

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

4.17

1.82

1.0

—

Dental operations

1.75

1.81

1.1

1.0

—

Covid-19 confirmed case

2.12

1.81

1.1

1.0

—

Pain in joint

1.76

1.80

1.0

—

Infections of the skin and subcutaneous tissue

137

1.74

1.80

1.0

—

Other skin changes

2.57

1.80

1.0

1.1

—

Urticaria and erythema

1.95

1.79

1.1

1.0

—

Other external causes of accidental injury

112

1.61

1.78

1.0

—

Dental operations, only avohilmo

1.69

1.78

1.1

1.0

—

Polyuria

2.34

1.77

1.0

—

Chronic lower respiratory diseases

187

1.48

1.77

1.0

—

Spinal stenosis

1.83

1.76

1.0

—

Dental caries 1, only avohilmo

103

1.64

1.76

1.1

1.0

—

Dental pulpitis 1

150

1.52

1.76

1.1

1.0

—

Dental pulpitis 4

150

1.52

1.76

1.1

1.0

—

Other diseases of upper respiratory tract

155

1.51

1.75

1.0

—

Coagulation defects, purpura and other haemorrhagic conditions

2.44

1.75

1.1

1.0

—

Other and unspecified myopathies

3.34

1.74

1.0

1.1

—

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

3.34

1.74

1.0

—

Asthma, excluding more controls

100

1.65

1.72

1.0

—

Asthma and allergy, excluding more controls

3.29

1.72

1.0

—

Vitamin deficiency

3.85

1.71

1.2

1.0

—

Vitamin deficiency, wide

3.85

1.71

1.2

1.0

—

Benign neoplasm: Adrenal gland

3.85

1.71

1.0

—

Other diseases of jaws

3.85

1.71

1.0

—

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

3.85

1.71

1.0

—

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

3.85

1.71

1.0

—

Melanocytic naevi

2.29

1.70

1.0

—

Metabolic disorders

163

1.52

1.67

1.1

1.0

—

Dementia, including avohilmo

1.87

1.67

1.0

—

DVT of lower extremities

2.38

1.67

1.0

—

Cervicocranial syndrome

3.16

1.66

1.0

—

Disorders of lens

126

1.60

1.65

1.0

—

Dental caries 3, only avohilmo

109

1.60

1.65

1.1

1.0

—

Acute bronchitis

1.86

1.65

1.0

—

N06DA Anticholinesterases

2.21

1.65

1.0

—

Use of anticholinesterases

2.21

1.65

1.0

—

Internal derangement of knee

1.85

1.64

1.0

—

Asthma and allergy

3.12

1.64

1.0

—

Sleep apnoea, including avohilmo

177

1.50

1.63

1.0

—

Other necrotizing vasculopathies

3.58

1.61

1.0

—

Hypopituitarism

3.57

1.61

1.0

—

Injury, poisoning and certain other consequences of external causes

1.77

1.61

1.1

1.0

—

Allergic rhinitis

2.08

1.61

1.0

—

Polyarthropathies

119

1.62

1.60

1.0

—

Other specific joint derangements/joint disorders

125

1.61

1.60

1.0

—

Insulin medication

128

1.67

1.60

1.0

—

Diabetes, varying definitions

173

1.49

1.60

1.0

—

Glomerular diseases

2.33

1.60

1.1

1.0

—

Gastric ulcer

2.33

1.60

1.1

1.0

—

Dental pulpitis 1, only avohilmo

159

1.48

1.59

1.1

1.0

—

Injuries to the ankle and foot

151

1.63

1.59

1.0

—

Dental pulpitis 4, only avohilmo

159

1.48

1.59

1.1

1.0

—

Diabetes mellitus

173

1.48

1.59

1.1

1.0

—

Asthma (mode)

106

1.61

1.58

1.0

—

Unspecified urinary incontinence

3.00

1.58

1.0

1.1

—

Reactive arthropathies

3.00

1.58

1.0

1.1

—

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

3.00

1.58

1.0

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

1.95

1.58

1.0

1.1

—

Abnormal findings on diagnostic imaging of other body structures

2.69

1.58

1.0

1.1

—

Diseases of pulp and periapical tissues, including avohilmo

150

1.49

1.58

1.1

1.0

—

Persons encountering health services in circumstances related to reproduction

101

1.68

1.57

1.0

—

Other and unspecified tonsillitis

1.96

1.56

1.0

1.1

—

Intestinal infectious diseases

197

1.50

1.56

1.1

1.0

—

Leiomyoma of uterus

1.69

1.56

1.0

—

Procreative management

2.00

1.55

1.1

—

Other and unspecified nonorganic psychotic disorders

2.27

1.53

1.0

—

Other viral diseases

2.03

1.52

1.1

1.0

—

Acute peritonitis

3.34

1.52

1.2

1.0

—

Asthma

105

1.58

1.50

1.0

—

Hyperlipidaemia, other/unspecified

1.83

1.50

1.0

—

Other heart diseases

1.83

1.49

1.0

—

Erysipelas

112

1.71

1.49

1.0

—

Varicose veins

121

1.62

1.49

1.0

—

Disorders of eyelid, lacrimal system and orbit

176

1.52

1.47

1.0

—

Chronic periapical parodontitis

2.22

1.46

1.0

—

Enthesopathies of lower limb, excluding foot

2.22

1.46

1.0

—

Unspecified haematuria

1.82

1.46

1.0

—

Asthma, hospital admissions , main diagnosis only

188

1.52

1.45

1.0

—

Lung diseases due to external agents

2.50

1.45

1.0

1.1

—

Shoulder lesions

127

1.54

1.44

1.1

1.0

—

Other disorders of optic [2nd] nerve and visual pathways

3.13

1.44

1.0

—

Sicca syndrome [Sjögren]

3.13

1.44

1.2

1.0

—

Disorders of muscles

3.13

1.44

1.2

1.0

—

Explicit bacterial Sepsis

3.13

1.44

1.0

1.1

—

Malignant neoplasm of kidney, except renal pelvis

2.73

1.43

1.0

1.1

—

Benign neoplasm of other and unspecified endocrine glands

2.73

1.43

1.0

—

Trochanteric bursitis

2.73

1.43

1.0

—

Insulin, intermediate and long-acting

130

1.66

1.43

1.0

—

Renal failure

100

1.74

1.43

1.1

1.0

—

Mental and behavioural disorders due to psychoactive substance use

155

1.58

1.40

1.0

—

Codes for special purposes

103

1.75

1.40

1.1

1.0

—

Provisional assignment of new diseases of uncertain etiology

103

1.75

1.40

1.1

1.0

—

Autoimmune diseases related-to ILD

201

1.49

1.39

1.1

1.0

—

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

2.42

1.39

1.1

1.0

—

Other disorders of skin and subcutaneous tissue, not elsewhere classified

2.42

1.39

1.0

—

Dermatitis and eczema

197

1.43

1.39

1.1

1.0

—

Sciatica+with lumbago

105

1.72

1.39

1.0

—

Vasomotor and allergic rhinitis

1.85

1.38

1.0

—

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

1.92

1.37

1.0

—

Malignant neoplasm of urinary organs

2.61

1.36

1.0

1.1

—

Other disorders of breast

2.61

1.36

1.0

—

Viral pneumonia

2.61

1.36

1.0

—

Other diseases of pleura

105

1.69

1.36

1.1

1.0

—

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

2.61

1.36

1.0

—

Early onset COPD, excluding more controls

2.19

1.36

1.0

—

Type 1 diabetes, wide definition, subgroup 1

2.19

1.36

1.1

1.0

—

Pneumonitis due to solids and liquids

2.94

1.36

1.0

—

Sequelae of infectious and parasitic diseases

2.94

1.36

1.0

1.1

—

Colorectal cancer, excluding all cancers (controls excluding all cancers)

2.15

1.35

1.0

—

Other arthrosis

107

0.47

1.35

1.0

—

Oter anti-inflammatory and antirheumatic agents, non-steroids

2.08

1.35

1.1

1.0

—

168

1.41

1.32

1.0

—

Voice disturbances

1.97

1.32

1.1

1.0

—

Impacted teeth

2.54

1.31

1.0

—

Injuries to the elbow and forearm

144

1.57

1.31

1.1

1.0

—

Insulin, combination of fast acting with intermediate-acting or long-acting

147

1.57

1.31

1.0

—

Malignant neoplasm of bronchus and lung

2.11

1.30

1.0

1.1

—

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

2.40

1.30

1.1

1.0

—

Substance use, excluding alcohol

2.09

1.30

1.0

—

Diseases of the ear and mastoid process

170

1.40

1.30

1.0

—

Diabetic nephropathy, excluding more controls

2.39

1.30

1.1

1.0

—

Schizophrenia or delusion, excluding more controls

1.95

1.30

1.0

—

Other blood glucose lowering drugs, excl. Insulins

2.35

1.29

1.0

—

Non-small cell lung cancer, adenocarcinoma

2.78

1.28

1.0

1.1

—

Non-small cell lung cancer, adenocarcinoma, helper endpoint

2.78

1.28

1.0

1.1

—

Ocular pain

2.78

1.28

1.0

1.1

—

Elevated blood glucose level

2.78

1.28

1.2

1.1

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

2.78

1.28

1.0

1.1

—

Benign neoplasm of major salivary glands

2.78

1.28

1.0

—

Other intervertebral disc disorders

126

1.51

1.28

1.0

—

Hernia of abdominal wall, postoperative

2.78

1.28

1.0

—

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

2.48

1.28

1.0

—

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

2.46

1.27

1.0

—

Other disorders of the musculoskeletal system and connective tissue

2.29

1.26

1.0

1.1

—

Bipolar affective disorders

2.29

1.26

1.0

1.1

—

Type 1 diabetes, wide definition

2.04

1.26

1.1

1.0

—

Persons encountering health services in other circumstances

1.78

1.26

1.0

—

Asthma (diagnoses ohter than nonallergic)

193

1.46

1.26

1.0

—

Diabetes medication

176

1.42

1.26

1.0

—

Transient ischemic attack

107

1.63

1.26

1.0

—

Asthma, unspecified (mode), excluding more controls

1.68

1.25

1.1

1.0

—

L04AD Calcineurin inhibitors

2.40

1.24

1.0

1.1

—

Pain in throat and chest

142

1.46

1.24

1.1

1.0

—

Familial hypercholesterolemia

2.22

1.24

1.0

—

Other and unspecified dermatitis

123

1.63

1.23

1.2

1.0

—

Fibroblastic disorders

2.00

1.23

1.0

—

Type 2 diabetes

168

1.41

1.22

1.1

1.0

—

Embedded and impacted teeth

2.19

1.22

1.1

1.0

—

Asthma-related pneumonia

1.76

1.22

1.1

1.0

—

Asthma-related pneumonia or sepsis

1.76

1.22

1.1

1.0

—

Asthma, hospital admissions 3, pneumonia

1.76

1.22

1.1

1.0

—

Syncope and collapse

1.77

1.22

1.0

—

Cyst of kidney

2.63

1.21

1.0

1.1

—

Benign neoplasm: Adrenal gland

2.63

1.21

1.0

1.1

—

Fibrosis and cirrhosis of liver

2.63

1.21

1.0

1.1

—

Pneumothorax

2.63

1.21

1.4

1.1

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

2.63

1.21

1.0

—

Other disorders of patella

2.16

1.21

1.0

—

Heart failure, not strict

151

1.46

1.19

1.0

—

Examination and observation for other reasons

1.64

1.18

1.0

—

All influenza (not pneumonia)

2.31

1.18

1.0

—

Other female pelvic inflammatory diseases

2.11

1.18

1.0

—

Contraceptive management

1.65

1.17

1.0

—

Complications of labour and delivery

1.58

1.17

1.0

—

Diabetic nephropathy

2.08

1.16

1.1

—

Pain and other conditions associated with female genital organs and menstrual cycle

2.07

1.16

1.0

—

Arthropathic psoriasis

0.00

1.16

0.0

1.1

—

Benign neoplasm of ovary

2.05

1.15

1.0

—

Ganglion

2.05

1.15

1.1

1.0

—

Orchitis and epididymitis

2.50

1.15

1.0

1.1

—

L02BA Anti-estrogens

2.05

1.15

1.1

1.0

—

Intracerebral haemorrhage

2.50

1.15

1.0

1.1

—

Chronic diseases of tonsils and adenoids

129

1.47

1.15

1.0

—

Malignant neoplasm of respiratory system and intrathoracic organs

2.00

1.15

1.0

—

Urticaria

1.81

1.14

1.1

1.0

—

Diseases of liver

1.72

1.14

1.1

1.0

—

Thoracic aortic aneurysm

0.00

1.14

0.0

1.0

—

Asthma, unspecified (mode)

1.62

1.13

1.1

1.0

—

Urolithiasis

1.75

1.12

1.0

—

Other disorders of kidney and ureter

2.34

1.12

1.0

1.1

—

Adhesive capsulitis of shoulder

2.33

1.12

1.3

1.0

—

Papulosquamous disorders

115

0.43

1.11

1.2

1.0

—

Insulin, fast-acting

1.70

1.10

1.1

1.0

—

Other disorders of veins

1.70

1.10

1.0

—

Benign neoplasms

147

1.41

1.10

1.0

—

Paroxysmal tachycardia

1.99

1.10

1.0

—

Pure hypercholesterolaemia

133

1.46

1.10

1.1

1.0

—

Use of donepezil

2.24

1.09

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes

2.38

1.09

1.0

—

Other and unspecified drugs and medicaments

2.38

1.09

1.0

—

Hydronephrosis

2.38

1.09

1.0

—

Endometriosis ASRM stages 1,2

2.19

1.08

1.0

—

Chronic kidney disease

1.81

1.07

1.1

1.0

—

Intestinal stricture

1.76

1.06

1.1

1.0

—

Chronic sinusitis

1.65

1.06

1.1

1.0

—

Other heart diseases, wide

171

1.38

1.05

1.0

—

Other viral diseases, not elsewhere classified

2.00

1.04

1.0

—

Other disorders of ear

173

1.39

1.04

1.0

—

Bell's palsy

2.27

1.03

1.0

—

Other metabolic disorders

2.27

1.03

1.0

—

Malignant neoplasm of rectum

2.27

1.03

1.0

1.1

—

Migraine without aura

2.27

1.03

1.0

1.1

—

Pleural effusion

2.06

1.02

1.0

1.1

—

Exclusions for E4_PCOS_BROAD

2.06

1.02

1.0

1.1

—

Calculus of kidney and ureter

1.73

1.02

1.0

—

Gastro-oesophageal reflux disease

158

1.46

1.02

1.1

1.0

—

Follow-up examination after treatment for conditions other than malignant neoplasms

1.73

1.02

1.0

—

Type 1 diabetes

1.88

1.00

1.2

1.0

—

Acute renal failure

1.88

1.00

1.1

1.0

—

Exposure to unspecified factor

204

1.37

1.00

1.0

—

Substance abuse

156

1.47

1.00

1.0

—

Redundant prepuce, phimosis and paraphimosis

1.87

1.00

1.1

1.0

—

Asthma, including avohilmo

197

1.33

0.98

1.0

—

Abnormal findings on examination of blood, without diagnosis

115

1.55

0.98

1.1

1.0

—

Type 2 diabetes, wide definition

149

1.40

0.98

1.1

1.0

—

Meniscus derangement

111

1.48

0.98

1.0

—

Benign neoplasm: salivary glands, exclude unknown (D119)

2.18

0.98

1.0

1.1

—

Memory loss

2.18

0.98

1.0

—

Familial hypercholesterolemia, with ischemic heart disease

2.18

0.98

1.0

—

Diseases of peritoneum

2.18

0.98

1.2

1.0

—

Trigger finger

2.17

0.98

1.2

1.0

—

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

2.18

0.98

1.0

1.1

—

Enterocolitis due to Clostridium difficile

2.17

0.98

1.0

—

Vitamin B12 deficiency anaemia

2.17

0.98

1.0

1.1

—

Other psoriatic arthropathies

0.00

0.97

0.0

1.1

—

Psoriatic arthropathies, ICD10

0.00

0.97

0.0

1.1

—

Pain (limb, back, neck, head abdominally)

1.45

0.97

1.0

—

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

166

1.36

0.96

1.1

1.0

—

Noninfective enteritis and colitis

116

1.55

0.95

1.0

—

Other functional intestinal disorders

111

1.54

0.94

1.0

—

Insulin, fast-acting or short human

1.61

0.93

1.1

1.0

—

Colorectal cancer

1.73

0.92

1.0

—

Disorders of refraction and accommodation

1.72

0.91

1.0

—

Polymyalgia rheumatica

2.14

0.91

1.0

—

Other maternal disorders predominantly related to pregnancy

100

0.57

0.91

1.0

—

Use of levodopa decarboxylase inhibitor

2.07

0.89

1.0

1.1

—

Disorder of lipoprotein metabolism, unspecified

2.07

0.89

1.0

—

Long labour

1.89

0.88

1.0

1.1

—

Other diseases of intestines

181

1.32

0.87

1.0

—

Special screening examination for infectious and parasitic diseases

1.87

0.87

1.0

—

Thyrotoxicosis, other and/or unspecified

1.86

0.87

1.1

1.0

—

Cervicobrachial syndrome

1.86

0.87

1.0

—

Other embolism and thrombosis

2.00

0.87

1.0

1.1

—

malignant neoplasm of female genital organs

2.00

0.87

1.0

—

Noninfectious colitis NAS

2.00

0.87

1.0

1.1

—

Radiculopathy

2.00

0.87

1.2

1.0

—

Nonorganic sleeping disorders, excluding more controls

2.00

0.87

1.0

1.1

—

Bronchitis

194

1.32

0.86

1.0

—

Diseases of salivary glands

1.82

0.85

1.0

—

Personality disorders, excluding more controls

1.82

0.85

1.0

1.1

—

Gastroduodenal ulcer

1.71

0.85

1.1

1.0

—

Diabetes, insulin treatment (Kela reimbursement)

181

1.32

0.85

1.1

1.0

—

Alcohol use disorder, Swedish definition

142

1.44

0.84

1.0

—

Arthropathies

128

1.35

0.84

1.0

—

Benign neoplasm of other and unspecified endocrine glands

1.94

0.84

1.0

1.1

—

Purpura and other haemorrhagic conditions

1.94

0.84

1.0

1.1

—

Alcohol abuse, main dg, excluding more controls

1.94

0.84

1.0

1.1

—

Other strabismus

1.77

0.84

1.1

1.0

—

Nonsuppurative otitis media

1.77

0.83

1.0

1.1

—

Congenital malformations, deformations and chromosomal abnormalities

139

1.45

0.83

1.0

—

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

100

0.52

0.83

1.2

1.0

—

Persons with potential health hazards related to communicable diseases

1.65

0.82

1.1

1.0

—

149

1.42

0.82

1.0

—

Other and unspecified urticaria

1.74

0.82

1.1

1.0

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

1.69

0.82

1.0

—

Ischemic heart diseases

154

1.34

0.82

1.1

1.0

—

Palmar fascial fibromatosis [Dupuytren]

1.88

0.81

1.0

—

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

1.87

0.81

1.0

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

1.73

0.81

1.1

1.0

—

Acute pharyngitis

1.86

0.81

1.0

—

Malignant neoplasm of skin

122

1.42

0.81

1.0

—

Obesity related asthma

1.57

0.81

1.0

—

Carbimazole or st.post thyroidectomy, condition for graves disease

1.70

0.80

1.1

1.0

—

In situ neoplasms

1.73

0.80

1.0

—

Mental and behavioural disorders due to alcohol

135

1.44

0.79

1.0

—

Ankylosing spondylitis, ICD10

0.00

0.79

0.0

1.0

—

Overexertion and strenuous or repetitive movements

0.00

0.79

0.0

1.0

—

Other disorders of bone

1.67

0.78

1.1

1.0

—

Paralytic ileus and intestinal obstruction

1.67

0.78

1.1

1.0

—

Gout

1.67

0.78

1.0

—

Diseases of the skin and subcutaneous tissue

150

1.30

0.78

1.1

1.0

—

Disorders of conjunctiva

173

1.35

0.78

1.0

—

Glucosamine medication

104

1.46

0.77

1.1

1.0

—

155

1.39

0.77

1.0

—

Somatoform disorder

1.77

0.76

1.0

1.1

—

Other disorders of skin and subcutaneous tissue

167

1.37

0.76

1.1

1.0

—

Artificial joint operation, meniscal resection

178

1.31

0.76

1.0

—

Acute nasopharyngitis (common cold)

1.75

0.75

1.0

1.1

—

Bacterial pneumoniae

1.55

0.75

1.1

1.0

—

Gout, FINNGEN

1.64

0.75

1.0

—

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

1.64

0.75

1.1

1.0

—

Type 2 diabetes, strict (exclude DM1)

165

1.30

0.74

1.0

—

Herpesviral [herpes simplex] infections

2.08

0.74

1.0

1.1

—

Undetermined asthma

2.08

0.74

1.2

1.0

—

Use of rivastigmine

2.08

0.74

1.0

—

Phlebitis and thrombophlebitis (not including DVT)

1.67

0.74

1.0

—

Soft tissue disorders related to use, overuse and pressure

1.67

0.74

1.0

—

Acute upper respiratory infections

179

1.29

0.74

1.0

—

Diseases of the respiratory system

1.40

0.74

1.1

1.0

—

Codeine

128

1.33

0.73

1.0

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

1.64

0.73

1.0

—

Other noninfective gastroenteritis and colitis

1.64

0.73

1.0

—

Gonarthrosis

109

1.37

0.73

1.0

—

Atopic dermatitis, strict definition

1.63

0.73

1.0

1.1

—

Other symptoms and signs involving the urinary system

2.00

0.72

1.0

1.1

—

Other/unspecified rheumatoid arthritis

2.00

0.72

1.2

1.1

—

Undetermined asthma, excluding more controls

2.00

0.72

1.2

1.0

—

Atopic dermatitis, strict definition with reimbursement

1.62

0.72

1.0

—

Chondropathies

1.80

0.72

1.1

1.0

—

Disorders of lipoprotein metabolism and other lipidaemias

142

1.33

0.72

1.1

1.0

—

Endometriosis of pelvic peritoneum

1.77

0.71

1.0

—

Melanocytic naevi

1.62

0.71

1.0

—

Leisure time condition

1.75

0.71

1.0

1.1

—

Benign neoplasm of major salivary glands

1.92

0.70

1.0

1.1

—

Assault

1.92

0.70

1.0

—

Pain in thoracic spine

1.92

0.70

1.0

—

Polyp of the female genital tract

1.58

0.70

1.0

—

Other nutritional deficiencies

156

1.38

0.70

1.0

—

Non-rheumatic valve diseases

1.44

0.70

1.0

—

Other hearing loss

1.55

0.69

1.0

—

Fracture of forearm

126

1.41

0.69

1.1

1.0

—

Hyperplasia of prostate

1.54

0.68

1.1

1.0

—

Arthropod-borne viral fevers and viral haemorrhagic fevers

1.85

0.68

1.0

1.1

—

Allergic contact dermatitis

1.85

0.68

1.0

—

Tinnitus

1.64

0.68

1.0

—

Persistent mood disorders

1.67

0.68

1.0

—

Thyrotoxicosis

1.53

0.68

1.1

1.0

—

Allergic conjunctivitis

133

1.41

0.68

1.0

—

Acute sinusitis

118

1.42

0.68

1.1

1.0

—

Diabetic retinopathy, strict definition

1.66

0.68

1.0

—

Postpartum hemorraghe, all women as controls

1.66

0.68

1.0

—

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

1.55

0.68

1.0

—

Valvular heart disease excluding rheumatic fever

1.43

0.67

1.0

—

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

1.54

0.67

1.0

—

Lumbar disc prolapse

121

1.38

0.66

1.0

—

Type 2 diabetes, definitions combined

163

1.28

0.66

1.0

—

Coxarthrosis [arthrosis of hip](FG)

1.40

0.65

1.0

—

Myocardial infarction, strict

0.61

0.65

1.0

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

126

1.40

0.65

1.0

—

Unspecified mental disorder

103

1.46

0.64

1.0

—

Sub-endpoint used in defining T1D endpoints

1.57

0.64

1.2

1.0

—

Coxarthrosis

1.40

0.64

1.0

—

Abnormal spermatozoa

1.72

0.64

1.2

1.0

—

Other disorders of the genitourinary system

1.72

0.64

1.0

—

Unspecified fall

111

1.43

0.63

1.0

—

Other chronic obstructive pulmonary disease, including avohilmo

121

1.37

0.63

1.0

—

Dementia in Alzheimer disease

1.71

0.63

1.0

—

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

1.51

0.62

1.0

—

Schizophrenia or delusion

1.52

0.62

1.0

—

Alcohol use disorder, ICD-based

104

1.44

0.62

1.0

—

Combinations of oral blood glucose lowering drugs

1.55

0.62

1.1

1.0

—

Other arthritis (FG)

1.55

0.62

1.0

—

Other inflammation of eyelid

1.67

0.61

1.0

1.1

—

Methotrexate

1.67

0.61

1.0

1.1

—

COPD (mode)

1.56

0.61

1.0

—

Superficial injury of hip and thigh

1.67

0.61

1.0

—

Acute alcohol intoxication, ICD10

1.60

0.61

1.0

—

Other (not insulin) diabetes medications

167

1.26

0.61

1.0

—

Conjunctivitis (acute, non atopic)

1.58

0.61

1.0

—

Otosclerosis

0.00

0.60

0.0

1.1

—

Foreign body entering into or through eye or natural orifice

0.00

0.60

0.0

1.1

—

Conductive hearing loss, unspecified

0.00

0.60

0.0

1.1

—

Pleural plaque

0.00

0.60

0.0

1.1

—

Ankylosing spondylitis

0.00

0.60

0.0

1.0

—

Disorders of gallbladder, biliary tract and pancreas

185

1.25

0.60

1.1

1.0

—

Normotensive glaucoma

0.00

0.60

0.0

1.0

—

Other and unspecified vascular occlusions

0.00

0.60

0.0

1.0

—

Disorders of continuity of bone

0.00

0.60

0.0

1.0

—

Anti-inflammatory and antirheumatic products, non-steroids

1.55

0.60

1.0

1.1

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

1.55

0.59

1.1

1.0

—

Schizophrenia, schizotypal and delusional disorders

1.50

0.59

1.0

—

Abscess of anal and rectal regions

0.00

0.59

0.0

1.1

—

Diabetic retinopathy, excluding more controls

1.61

0.59

1.1

1.0

—

Cholelithiasis, broad definition with cholecystitis

167

1.27

0.58

1.0

—

Reimbursement for rheumatic diseases

148

1.35

0.58

1.1

1.0

—

Conjunctivitis

167

1.30

0.58

1.0

—

Biguanides

172

1.25

0.58

1.0

—

Infections of genitourinary tract in pregnancy

0.00

0.58

0.0

1.0

—

Psoriatic arthropathies

0.00

0.58

0.0

1.0

—

Poisoning by drugs, medicaments and biological substances

1.51

0.58

1.0

—

Acute laryngitis and tracheitis

0.00

0.58

0.0

1.0

—

Parkinson's disease

1.71

0.57

1.0

1.1

—

Glucagon-like peptide-1 (GLP-1) analogues

115

1.36

0.57

1.0

—

Gonarthrosis [arthrosis of knee](FG)

128

1.29

0.57

1.0

—

Mental and behavioural disorders due to alcohol, excluding acute intoxication

115

1.39

0.56

1.0

—

Appendectomy

161

1.32

0.56

1.0

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

1.62

0.55

1.0

1.1

—

Parkinson's disease, including avohilmo

1.62

0.55

1.0

1.1

—

Degeneration of macula and posterior pole

101

0.65

0.55

1.0

—

Early onset COPD

1.50

0.54

1.0

1.1

—

Fall on and from stairs and steps

1.50

0.54

1.0

—

Effects of foreign body entering through natural orifice

1.50

0.54

1.0

—

Endometriosis of ovary

1.58

0.54

1.0

—

Sensorineural hearing loss

148

1.28

0.54

1.0

—

Artrosis, including avohilmo

163

0.77

0.53

1.0

—

Acute upper respiratory infections of multiple and unspecified sites

139

1.29

0.53

1.0

—

Nontraumatic intracranial haemmorrhage

1.54

0.53

1.0

1.1

—

Other gastritis (incl. Duodenitis)

1.45

0.53

1.0

—

Superficial injury of lower leg

1.43

0.52

1.1

1.0

—

Acute alcohol intoxication

1.43

0.52

1.0

—

Behavioural syndromes associated with physiological disturbances and physical factors

1.43

0.52

1.0

—

Cholecystectomy

173

1.28

0.52

1.0

—

Pregnancy hypertension

0.60

0.52

1.2

1.0

—

Alcohol abuse, main dg

1.50

0.51

1.0

—

Other (seronegative) rheumatoid arthritis, wide

1.50

0.51

1.2

1.1

—

Other respiratory diseases principally affecting the interstitium

1.50

0.51

1.2

1.1

—

Glaucoma

138

0.70

0.51

1.0

—

Insomnia

1.46

0.50

1.0

—

Malignant neoplasm of breast, HER-negative

1.46

0.50

1.2

1.0

—

Functional dyspepsia

1.49

0.49

1.0

—

Disorders of adult personality and behaviour

1.49

0.49

1.0

—

Postpartum haemorrhage

1.56

0.49

1.0

1.1

—

Gout, unspecified

1.56

0.48

1.0

—

5-aminosalicylic acid

1.56

0.48

1.0

—

Diseases of arteries, arterioles and capillaries (FINNGEN)

1.53

0.48

1.3

1.0

—

Disorders of breast

102

1.36

0.48

1.1

1.0

—

Disorders of skin appendages

119

1.34

0.48

1.0

1.1

—

Postpartum hemorraghe, parous women as controls

1.49

0.47

1.0

1.1

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

1.49

0.47

1.0

—

Acute pancreatitis (for exclusion)

1.49

0.47

1.0

—

COPD

1.35

0.47

1.0

—

Acute pancreatitis

1.46

0.46

1.0

—

Bacterial pneumonia, not elsewhere classified

1.42

0.46

1.1

1.0

—

Dental caries 3 and operation codes, only avohilmo

1.42

0.46

1.2

1.0

—

Unspecific neurodegenerative disorder

1.43

0.46

1.0

—

Injuries to the thorax

111

1.35

0.46

1.1

1.0

—

Bacterial pneumonia (organism specified)

101

1.35

0.46

1.1

1.0

—

Peritonsillar abscess

1.43

0.46

1.0

—

Endometriosis

1.43

0.45

1.0

—

Striking against or struck by other objects

1.43

0.45

1.0

1.1

—

Type 2 diabetes, definitions combined, including avohilmo

166

1.21

0.45

1.0

—

Use of pramipexole

1.40

0.45

1.0

—

Poisoning by medicine

1.40

0.45

1.0

—

Benign lipomatous neoplasm

1.40

0.45

1.0

—

Conductive and sensorineural hearing loss

151

1.24

0.44

1.0

—

Colonic or urogenital fistula

1.45

0.44

1.0

—

Fracture of rib(s), sternum and thoracic spine

1.45

0.44

1.0

—

Asthma/COPD (KELA code 203)

186

1.21

0.44

1.0

—

Other chronic obstructive pulmonary disease

1.34

0.44

1.0

—

Other abnormal uterine and vaginal bleeding

1.46

0.43

1.1

1.0

—

Myocardial infarction

101

0.71

0.43

1.0

—

Cholecystitis

1.61

0.43

1.0

1.1

—

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

1.61

0.43

1.0

—

Injuries to the shoulder and upper arm

192

1.22

0.42

1.0

—

Glaucoma suspect

0.66

0.42

1.0

—

Coeliac disease

1.56

0.42

1.0

1.1

—

Benign mammary dysplasia

1.56

0.42

1.0

—

Seropositive rheumatoid arthritis, strict definition

1.56

0.42

1.0

1.1

—

Iron deficiency anaemia secondary to blood loss (chronic)

1.56

0.42

1.0

1.1

—

Biological medication for rheuma

1.56

0.42

1.0

1.1

—

Keratitis

1.38

0.42

1.0

—

Disorders of sclera, cornea, iris and ciliary body

131

1.30

0.42

1.0

—

Contact with and exposure to communicable diseases

1.37

0.41

1.0

—

Chronic pancreatitis

1.52

0.41

1.2

1.1

—

Unspecified acute lower respiratory infection

1.52

0.41

1.2

1.1

—

Other diseases of lip and oral mucosa

1.52

0.41

1.0

—

Direct fill therapy

1.52

0.41

1.0

1.1

—

Congenital malformations of the circulatory system

1.51

0.41

1.0

1.1

—

D07AA Corticosteroids, weak (group I)

1.51

0.41

1.0

1.1

—

Oral leukoplakia and related diseases

0.00

0.41

0.0

1.1

—

Fracture of neck

0.00

0.41

0.0

1.0

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Neuronal Ab [Presence] in Cerebral spinal fluid

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS