No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1048 |
4. Check minimum number of eventsNone |
1048 |
5. Include endpointsNone |
1048 |
6. Filter based on genotype QC (FinnGen only) |
900 |
Control definitions (FinnGen only)
- Control exclude
- AB1_TUBERCULOSIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Tuberculosis of other organs, strict
based on the number of shared cases.
Similar with more cases:
- Tuberculosis, wide
- Tuberculosis, wide, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14840 | 7877 | 6491 |
| Only index persons | 8037 | 4922 | 3115 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.21 | 0.23 | 0.18 |
| Only index persons | 0.16 | 0.18 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 54.25 | 54.45 | 54.01 |
| Only index persons | 46.80 | 48.59 | 43.96 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 900 | 458 | 442 |
| Unadjusted period prevalence (%) | 0.18 | 0.16 | 0.20 |
| Median age at first event (years) | 48.67 | 45.66 | 51.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 945
- Matched controls
- 9450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A18.2
ICD-10 Finland
Tuberculous peripheral lymphadenopathy
+∞
129.2
121
*
01710
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum colli
+∞
125.9
118
*
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
37.1
89.5
56
16
A18.0
ICD-10 Finland
Tuberculosis of bones and joints
+∞
52.6
50
*
01908
ICD-8 Finland
Late effects of tuberculosis, Sequelae aliae o tuberculosis organorum respirationis
+∞
52.6
50
*
01600
ICD-8 Finland
Tuberculosis of genito-urinary system, Renis
+∞
44.1
42
*
A18.4
ICD-10 Finland
Tuberculosis of skin and subcutaneous tissue
+∞
42.0
40
*
0172A
ICD-9 Finland
Tuberculosis of other organs, Peripheral lymph nodes
+∞
40.9
39
*
A18.1
ICD-10 Finland
Tuberculosis of genitourinary system
+∞
39.9
38
*
M49.0*A18.0
ICD-10 Finland
Tuberculosis of spine
+∞
35.6
34
*
A18.8
ICD-10 Finland
Tuberculosis of other specified organs
+∞
35.6
34
*
A70
ICPC
Tuberculosis
186.9
35.0
36
*
01102
ICD-8 Finland
Pulmonary tuberculosis, Non cavernosa
+∞
32.5
31
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
8.8
29.8
38
45
01718
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum periphericorum aliorum
+∞
25.1
24
*
Y3429
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Other inactive tuberculosis cases
+∞
22.0
21
*
A18.3
ICD-10 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands
+∞
20.9
20
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.5
20.4
51
119
01500
ICD-8 Finland
Tuberculosis of bones and joints, Of vertebral column
+∞
18.8
18
*
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
+∞
18.8
18
*
N33.0*A18.1
ICD-10 Finland
Tuberculous cystitis
+∞
18.8
18
*
01797
ICD-8 Finland
Tuberculosis of other organs, Suspecta
+∞
18.8
18
*
Y3409
ICD-8 Finland
Follow-up examination of illness, accident or surgery, Treated inactive pulmonary tuberculosis
39.3
18.6
23
6
01904
ICD-8 Finland
Late effects of tuberculosis, Adhaesiones pleurae
+∞
16.7
16
*
M01.1*A18.0
ICD-10 Finland
Tuberculous arthritis
+∞
16.7
16
*
01909
ICD-8 Finland
Late effects of tuberculosis, Sequelae NUD o tuberculosis organorum respirationis
+∞
15.7
15
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.6
15.6
53
155
1370X
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,MUU JÄLKITILA]
162.6
15.5
16
*
PJA10
NOMESCO Finland
Exploration of lymph nodes
6.0
15.3
27
46
B90.2
ICD-10 Finland
Sequelae of tuberculosis of bones and joints
152.3
14.5
15
*
01597
ICD-8 Finland
Tuberculosis of bones and joints, Suspecta
+∞
13.6
13
*
01608
ICD-8 Finland
Tuberculosis of genito-urinary system, Suspecta
+∞
12.5
12
*
L04AX01
ATC
azathioprine; systemic
3.3
12.0
45
140
01930
ICD-8 Finland
Late effects of tuberculosis, Columnae vertebralis
+∞
11.5
11
*
A15.1
ICD-10 Finland
Tuberculosis of lung, confirmed by culture only
+∞
11.5
11
*
01510
ICD-8 Finland
Tuberculosis of bones and joints, Of hip
+∞
11.5
11
*
0151X
ICD-9 Finland
Tuberculosis of bones and joints, Hip[TUBERCULOSIS COXAE,EPÄILTY]
+∞
11.5
11
*
01901
ICD-8 Finland
Late effects of tuberculosis, Emphysema
+∞
11.5
11
*
01588
ICD-8 Finland
Tuberculosis of bones and joints, Of other specified bones and joints
+∞
11.5
11
*
01701
ICD-8 Finland
Tuberculosis of other organs, Erythema induratum tuberculosum
+∞
11.5
11
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
11.1
129
691
H02AB06
ATC
prednisolone; systemic
1.6
10.7
448
3429
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
10.6
242
1595
01220
ICD-8 Finland
Other respiratory tuberculosis, Pleurisy with effusion without mention of cause
+∞
10.4
10
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
10.1
138
779
H02AB07
ATC
prednisone; oral
1.8
9.5
152
903
H03.1*A18.4
ICD-10 Finland
Lupus vulgaris: of eyelid
+∞
9.4
9
*
01903
ICD-8 Finland
Late effects of tuberculosis, Fibrosis pulmonum
+∞
9.4
9
*
0150X
ICD-9 Finland
Tuberculosis of bones and joints, Vertebral column[SELKÄRANKATUBERKULOOSI,EPÄILTY]
+∞
9.4
9
*
H32.0*A18.5
ICD-10 Finland
Lupus chorioretinitis
+∞
9.4
9
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.2
326
2380
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
9.1
58
242
J96.1
ICD-10 Finland
Chronic respiratory failure
3.1
8.9
37
123
J01MA12
ATC
levofloxacin; systemic
1.7
8.9
195
1266
R50.9
ICD-10 Finland
Fever, unspecified
1.8
8.8
146
874
C03DA01
ATC
spironolactone; oral
1.8
8.7
154
940
C03CA01
ATC
furosemide; systemic
1.5
8.7
433
3391
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.5
8.5
54
225
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
8.5
151
923
01931
ICD-8 Finland
Late effects of tuberculosis, Coxae
+∞
8.3
8
*
01900
ICD-8 Finland
Late effects of tuberculosis, Bronchiectasia
+∞
8.3
8
*
K93.0*A18.3
ICD-10 Finland
Tuberculous disease of the intestines, peritoneum and mesentery glands
+∞
8.3
8
*
01604
ICD-8 Finland
Tuberculosis of genito-urinary system, Prostatae, vesiculae seminalis sive testis
+∞
8.3
8
*
M90.0*A18.0
ICD-10 Finland
Bentuberculosis
+∞
8.3
8
*
0140X
ICD-9 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands, Tuberculous peritonitis[PERITONITIS TUBERCULOSA,EPÄILTY]
+∞
8.3
8
*
01719
ICD-8 Finland
Tuberculosis of other organs, Lymphonodorum NUD
+∞
8.3
8
*
A19.1
ICD-10 Finland
Acute miliary tuberculosis of multiple sites
+∞
8.3
8
*
M79.3
ICD-10 Finland
Panniculitis, unspecified
17.3
8.1
12
7
SPAT1254
SPAT
Administration of medicine
1.7
7.8
166
1067
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.4
7.7
19
44
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.7
136
830
G04AB05, ,
ATC
3.0
7.6
32
108
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.9
7.4
102
576
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
7.4
361
2789
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
7.3
32
110
H02AB04
ATC
methylprednisolone; systemic
1.7
7.3
136
841
N29.1*A18.1
ICD-10 Finland
Tuberculosis of the kidney or ureter
+∞
7.3
7
*
01107
ICD-8 Finland
Pulmonary tuberculosis, Suspecta
+∞
7.3
7
*
A18.5
ICD-10 Finland
Tuberculosis of eye
+∞
7.3
7
*
1373X
ICD-9 Finland
Late effects of tuberculosis of bones and joints
+∞
7.3
7
*
B90.0
ICD-10 Finland
Sequelae of central nervous system tuberculosis
+∞
7.3
7
*
0178X
ICD-9 Finland
Tuberculosis of other organs, Oesophagus[TUBERCULOSIS ALIORUM ORGANORUM]
+∞
7.3
7
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
7.3
161
1043
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.9
7.2
93
515
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.2
374
2923
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.0
172
1142
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.0
448
3636
49300
ICD-8 Finland
Asthma, bronchiale
2.9
6.8
31
109
R03DA04
ATC
theophylline; systemic, rectal
1.9
6.8
81
436
R03AC12
ATC
salmeterol; inhalant
2.1
6.8
61
296
P01BA02
ATC
hydroxychloroquine; oral
2.0
6.8
72
372
R03BA01
ATC
beclometasone; inhalant
1.7
6.8
131
818
1370A
ICD-9 Finland
Late effects of tuberculosis, Late effects of respiratory or unspecified tuberculosis[HENGITYSELINTUBERKUL JÄLKITILA,TUBERKULOOSIARPI]
40.3
6.8
8
*
4701
FHL
Neck lymph node removal
40.3
6.8
8
*
S01AD03
ATC
aciclovir; ophthalmic
2.5
6.8
41
168
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.7
275
2046
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
2.9
6.6
31
111
Z03.0
ICD-10 Finland
Observation for suspected tuberculosis
7.9
6.6
14
18
KCD02
NOMESCO Finland
Transurethral resection of bladder
2.6
6.6
36
140
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.4
6.6
23
69
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.9
6.5
29
101
J01DA01
ATC
[U] cefalexin
1.4
6.4
543
4609
40299
ICD-8 Finland
Hypertensive heart disease
4.1
6.4
17
42
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.1
6.4
57
277
01401
ICD-8 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands, Peritonei et lymphonodorum mesenterii
+∞
6.3
6
*
01731
ICD-8 Finland
Tuberculosis of other organs, Otitis media tuberculosa
+∞
6.3
6
*
01210
ICD-8 Finland
Other respiratory tuberculosis, Tuberculosis pleurae, pleuritis exsudativa tuberculosa
+∞
6.3
6
*
01407
ICD-8 Finland
Tuberculosis of intestines, peritoneum and mesenteric glands, Suspecta
+∞
6.3
6
*
A15.4
ICD-10 Finland
Tuberculosis of intrathoracic lymph nodes, confirmed bacteriologically and histologically
+∞
6.3
6
*
01101
ICD-8 Finland
Pulmonary tuberculosis, Cavernosa
+∞
6.3
6
*
212
Kela drug reimbursment
Gout
2.8
6.2
30
110
JN4AD
NOMESCO Finland
Body CT examination
1.7
6.1
108
658
L04AA06
ATC
mycophenolic acid; systemic
4.2
6.1
16
39
A46
ICD-10 Finland
Erysipelas
1.6
6.1
152
1013
Z20.1
ICD-10 Finland
Contact with and exposure to tuberculosis
10.1
6.0
11
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.0
266
2003
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
140
307
5.18
61.35
4.5
2.8
—
—
—
0
0
67
201
3.51
18.93
2.0
1.5
1.96
0.13
iu/ml
2.00
20
42
61
191
3.35
16.12
2.5
1.3
—
—
—
0
0
55
183
3.13
13.18
2.0
1.5
—
—
—
0
0
73
287
2.67
12.94
1.6
2.1
38.54
38.97
u/l
0.06
63
251
54
185
3.04
12.32
1.6
2.0
11.85
13.65
mg/l
0.86
46
169
18
11
16.66
11.69
2.2
1.3
—
—
—
0
0
105
539
2.07
10.11
2.8
2.9
10.67
10.92
g/l
0.20
96
488
60
258
2.42
8.87
2.1
1.6
4.41
8.47
iu/ml
1.22
17
68
54
225
2.48
8.54
1.2
1.2
0.33
1.91
u/ml
—
6
15
92
487
1.99
8.13
4.2
3.9
1.93
2.04
mmol/l
0.10
71
361
31
100
3.17
7.89
5.7
3.5
—
—
—
0
0
33
111
3.04
7.83
3.5
2.9
191.80
2310.27
u/ml
—
5
11
163
1072
1.63
6.93
6.4
7.5
5.15
5.10
kpa
0.23
157
1024
163
1073
1.63
6.90
6.3
7.4
11.28
11.56
kpa
0.35
156
1025
24
72
3.39
6.86
1.3
1.3
14.08
13.61
u/l
0.15
24
66
159
1058
1.60
6.42
6.5
7.5
0.96
1.13
mmol/l
0.20
135
853
11
10
11.11
6.30
1.0
1.0
—
—
—
0
0
29
104
2.85
6.20
1.5
1.2
—
—
—
0
0
74
402
1.91
6.09
1.8
1.9
8.20
2.35
ug/l
0.55
64
343
26
91
2.91
5.81
1.5
1.4
157.90
171.98
au/ml
—
10
26
27
98
2.81
5.67
1.6
1.2
281.50
309.53
u/ml
0.17
14
47
221
1638
1.46
5.34
2.2
1.9
—
—
—
0
0
186
1336
1.49
5.27
4.0
3.0
0.81
0.82
mmol/l
0.46
181
1242
57
299
1.96
5.23
4.2
4.3
24.95
25.06
mmol/l
0.10
50
275
15
31
4.90
5.13
1.7
1.9
978.53
861.97
u/ml
0.13
15
31
484
4118
1.36
5.11
8.3
6.2
11.16
12.06
umol/l
1.07
461
3908
309
2461
1.38
4.91
2.9
2.5
63.86
95.52
u/l
0.47
286
2267
31
132
2.39
4.78
1.2
1.2
48.15
39.56
u/ml
—
8
15
15
34
4.47
4.76
2.7
4.6
—
—
—
0
0
13
26
5.05
4.64
1.3
2.1
—
—
—
0
0
13
26
5.05
4.64
1.3
2.1
—
—
—
0
0
20
69
2.94
4.62
1.1
1.1
—
—
—
0
0
21
75
2.84
4.57
1.2
1.7
—
—
—
0
0
21
75
2.84
4.57
1.2
1.7
—
—
—
0
0
21
75
2.84
4.57
1.2
1.7
—
—
—
0
0
13
27
4.87
4.51
1.4
2.0
—
—
—
0
0
15
38
3.99
4.31
1.3
1.8
—
—
—
0
0
15
38
3.99
4.31
1.3
1.8
—
—
—
0
0
15
38
3.99
4.31
1.3
1.8
—
—
—
0
0
15
38
3.99
4.31
1.3
1.8
—
—
—
0
0
36
172
2.14
4.28
1.1
1.3
2.23
2.80
u/ml
—
6
21
36
173
2.12
4.22
1.2
1.3
1.59
4.38
u/ml
—
7
30
290
2339
1.35
4.13
2.9
2.4
2.92
3.03
mg/l
0.32
257
1986
31
142
2.22
4.09
1.2
1.2
—
—
—
0
0
30
136
2.25
4.06
10.0
4.5
1756.25
303.64
iu/ml
—
8
14
11
22
5.05
4.01
1.3
1.1
202.50
109.40
ng/l
—
6
5
20
75
2.70
4.01
1.3
1.2
1.33
6.61
u/ml
—
9
31
59
343
1.77
3.99
2.3
1.9
—
—
—
0
0
174
1298
1.42
3.99
1.6
1.5
2.84
2.62
g/l
0.46
110
727
248
1971
1.35
3.86
3.8
2.9
362.03
358.06
umol/l
0.21
219
1670
98
656
1.55
3.85
1.8
1.6
—
—
—
0
0
19
71
2.71
3.84
1.3
1.1
1.88
1.25
u/ml
—
8
20
484
4232
1.29
3.76
9.6
7.1
1.21
1.21
mmol/l
0.07
429
3603
41
219
1.91
3.64
1.2
1.3
—
—
—
0
0
139
1014
1.43
3.60
4.2
4.0
253.36
256.59
u/l
0.09
133
956
52
302
1.76
3.55
3.6
3.0
24.84
24.90
mmol/l
0.04
52
297
156
1166
1.40
3.53
1.4
1.3
25.40
35.91
iu/ml
0.98
48
375
20
81
2.50
3.48
1.4
1.9
—
—
—
0
0
15
52
2.92
3.47
1.1
1.1
—
—
—
0
0
111
781
1.48
3.47
2.2
2.9
66.27
66.02
g/l
0.12
96
709
476
4188
1.28
3.39
13.1
8.9
4.58
4.28
e9/l
1.25
417
3629
430
3740
1.27
3.35
6.0
4.8
33.93
34.60
g/l
1.50
398
3467
19
77
2.50
3.31
1.4
1.9
—
—
—
0
0
16
60
2.70
3.24
1.2
1.3
—
—
—
0
0
191
1496
1.35
3.23
3.4
2.5
10.74
11.84
umol/l
1.62
176
1387
19
78
2.47
3.23
1.5
1.2
—
—
—
0
0
436
3817
1.26
3.16
8.7
6.4
1.21
1.21
mmol/l
0.29
413
3469
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
299
1.71
3.12
3.2
2.7
0.36
0.36
iu/ml
0.02
30
168
6
8
7.54
3.06
1.0
1.5
—
—
—
0
0
30
154
1.98
3.02
1.5
1.4
—
—
—
0
0
162
1251
1.36
3.00
2.0
1.9
—
—
—
0
0
450
3975
1.25
2.95
5.6
4.5
0.02
3.93
estimate
0.79
103
891
444
3923
1.25
2.88
5.5
4.5
0.00
0.00
estimate
-0.00
99
861
113
828
1.41
2.87
3.4
2.8
4.09
4.32
kpa
0.74
108
802
33
179
1.87
2.85
1.2
1.3
—
—
—
0
0
40
231
1.76
2.84
4.4
2.8
7.83
7.92
kpa
0.13
40
225
97
694
1.44
2.81
2.2
1.9
385.28
393.04
nmol/l
0.08
89
625
37
210
1.79
2.78
2.9
1.6
15140.52
16661.63
e6/l
0.09
25
147
450
4003
1.24
2.68
5.6
4.5
0.00
0.37
estimate
0.52
99
840
27
140
1.96
2.67
1.2
1.2
3.81
3.75
mmol/l
0.09
27
132
83
584
1.46
2.63
8.4
8.9
1.28
1.34
%
0.31
83
579
32
178
1.83
2.58
1.6
1.5
—
—
—
0
0
38
223
1.73
2.57
1.7
1.6
—
—
—
0
0
8
20
4.03
2.57
1.0
1.0
1363.38
1306.80
miu/ml
—
8
20
269
2270
1.26
2.56
5.5
4.6
0.00
0.01
estimate
0.96
88
763
124
942
1.36
2.56
4.8
3.3
1.99
1.95
mmol/l
0.04
112
789
103
759
1.40
2.55
2.3
2.1
140.71
150.83
ug/g
0.15
77
591
31
172
1.83
2.53
4.2
2.3
15.78
15.86
%
0.05
31
167
37
217
1.73
2.52
1.6
1.5
—
—
—
0
0
98
718
1.41
2.51
5.4
3.5
120.06
91.80
ng/l
1.37
89
609
18
82
2.22
2.48
1.2
1.3
323.62
280.26
pmol/l
0.16
13
71
37
220
1.71
2.41
2.2
1.4
—
—
—
0
0
165
1319
1.30
2.41
3.6
2.5
20.56
21.08
%
0.20
153
1222
299
2569
1.24
2.40
2.3
2.2
152.59
275.55
u/l
2.18
274
2417
49
314
1.59
2.40
2.1
1.8
—
—
—
0
0
9
27
3.36
2.39
1.2
1.1
473.78
179.65
iu/ml
—
9
27
67
461
1.49
2.39
1.7
1.7
1.55
1.57
g/l
0.06
60
414
5
8
6.28
2.37
1.0
1.3
—
—
—
0
0
342
2990
1.23
2.32
5.2
3.6
—
—
—
0
0
104
785
1.37
2.25
2.9
2.2
0.19
0.20
g/l
0.97
97
720
78
561
1.43
2.23
1.5
1.5
—
—
—
0
0
14
60
2.35
2.22
1.1
1.2
—
61.88
—
0
8
5
9
5.58
2.21
1.0
1.2
—
—
—
0
0
49
321
1.56
2.21
2.0
3.7
44.49
70.67
mg/l
0.76
38
281
49
322
1.55
2.18
2.0
3.7
30.52
65.15
mg/l
1.81
38
283
607
6483
0.82
2.18
5.5
5.2
4.39
4.45
mmol/l
0.71
554
5864
506
4618
1.21
2.17
6.4
5.2
6.62
6.83
mmol/l
1.66
488
4406
148
1185
1.30
2.14
2.0
1.9
—
—
—
0
0
17
81
2.12
2.13
2.1
1.2
0.23
0.21
nmol/l
0.36
12
57
579
5357
1.21
2.13
7.4
4.4
17.72
14.91
mm/h
2.96
540
4916
625
6649
0.82
2.11
6.1
6.1
2.50
2.54
mmol/l
0.58
569
5997
602
6427
0.83
2.11
5.3
5.1
1.44
1.46
mmol/l
0.48
544
5773
8
25
3.22
2.09
1.1
1.1
—
—
—
0
0
35
214
1.66
2.09
3.6
2.0
121.61
125.01
g/l
0.37
28
165
267
2298
1.23
2.08
3.7
3.0
32.69
36.12
u/l
0.64
255
2155
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
31
2.92
2.07
1.0
1.1
—
—
—
0
0
159
1291
1.28
2.07
2.4
2.0
30.20
29.58
s
0.56
153
1248
172
1411
1.27
2.06
3.5
2.5
2.26
2.26
g/l
0.03
156
1295
6
15
4.02
2.04
1.0
1.1
—
—
—
0
0
341
3012
1.21
2.04
4.0
3.4
1815.85
1990.63
ng/l
0.31
294
2619
29
170
1.73
2.02
1.4
1.2
—
—
—
0
0
11
44
2.52
2.01
1.2
1.0
—
—
—
0
0
226
2638
0.81
2.01
2.0
1.9
1.36
1.30
mmol/l
0.43
193
2166
7
21
3.35
1.96
1.1
1.0
—
—
—
0
0
8
27
2.98
1.94
1.1
1.3
—
—
—
0
0
8
27
2.98
1.94
3.1
2.6
76.13
97.74
%
—
8
27
17
85
2.02
1.91
2.1
2.3
2.75
2.14
u/field
—
8
43
38
244
1.58
1.90
1.3
1.6
—
—
—
0
0
7
22
3.20
1.88
1.0
1.1
—
—
—
0
0
6
17
3.54
1.84
1.0
1.1
—
—
—
0
0
444
4047
1.18
1.82
17.8
19.0
1.35
1.36
inr
0.10
376
3394
44
296
1.51
1.80
2.0
3.6
2.41
2.69
ratio
0.14
26
178
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
6
18
3.35
1.75
1.0
1.1
—
—
—
0
0
382
3450
1.18
1.72
3.0
2.4
77.48
79.18
nmol/l
0.53
340
3019
5
13
3.86
1.71
1.2
1.2
—
—
—
0
0
134
1092
1.26
1.71
1.4
1.3
18.27
12.97
u/ml
0.22
48
369
30
188
1.62
1.67
1.8
1.6
—
—
—
0
0
46
319
1.46
1.65
1.2
1.2
—
—
—
0
0
5
14
3.58
1.61
1.2
1.1
18.00
30.70
u/l
—
5
9
227
1971
1.20
1.59
4.1
2.8
5.50
5.79
e6/l
0.12
205
1800
17
92
1.86
1.56
2.3
1.2
0.67
20.40
nmol/l
0.49
17
86
35
232
1.53
1.56
1.9
1.6
—
—
—
0
0
380
3452
1.17
1.56
3.4
2.9
—
—
estimate
—
0
0
552
5163
1.17
1.55
7.7
5.6
135.75
2683.78
e6/l
2.57
16
97
25
153
1.65
1.54
1.8
1.5
—
—
—
0
0
8
33
2.44
1.54
1.0
1.1
—
—
—
0
0
7
27
2.60
1.51
1.3
1.2
—
—
—
0
0
68
515
1.35
1.50
3.9
3.8
44.15
46.70
%
0.40
68
505
583
6161
0.86
1.46
4.6
4.4
1.28
1.25
mmol/l
0.39
524
5456
218
1902
1.19
1.44
3.3
2.5
—
—
—
0
0
17
95
1.80
1.43
1.1
1.4
—
—
—
0
0
9
39
2.32
1.43
1.1
1.1
—
—
—
0
0
80
626
1.30
1.42
1.7
1.7
—
—
—
0
0
21
126
1.68
1.41
1.6
1.2
1328.06
1316.10
e6/l
0.01
16
84
22
134
1.66
1.40
1.9
1.6
1.55
1.64
mmol/l
0.28
22
129
7
29
2.42
1.39
1.0
1.3
—
—
—
0
0
5
120
0.41
1.38
1.6
1.4
—
—
—
0
0
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
17
97
1.77
1.35
1.8
1.7
87.58
89.62
%
0.44
17
97
17
97
1.77
1.35
1.1
1.4
—
—
—
0
0
17
97
1.77
1.35
1.2
1.4
—
—
—
0
0
49
359
1.38
1.35
2.8
2.5
10.43
10.81
g/l
0.20
38
315
99
803
1.26
1.34
2.6
2.6
10.11
5.72
ug/l
0.50
82
681
11
54
2.05
1.33
1.2
1.1
—
—
—
0
0
700
7274
0.85
1.31
41.9
29.3
128.99
131.03
g/l
2.92
693
7159
700
7273
0.86
1.30
42.4
29.5
38.58
39.15
%
1.60
691
7152
700
7273
0.86
1.30
41.6
29.0
4.32
4.35
e12/l
0.76
682
7073
700
7271
0.86
1.29
41.7
29.0
244.15
242.07
e9/l
0.32
687
7092
700
7271
0.86
1.29
41.5
28.9
91.56
91.74
fl
0.42
691
7155
108
891
1.24
1.27
2.8
2.7
7.27
8.59
umol/l
0.68
98
785
18
107
1.70
1.26
1.2
1.1
—
—
—
0
0
326
2967
1.15
1.26
5.6
4.7
5.57
0.05
estimate
0.49
90
717
66
513
1.31
1.25
1.5
1.5
—
—
—
0
0
5
116
0.43
1.25
1.0
1.2
1.47
1.57
g/l
—
5
116
74
585
1.29
1.24
4.6
3.1
51.82
58.59
ml/min/173m2
0.76
33
263
23
147
1.58
1.24
1.6
1.7
—
—
—
0
0
16
93
1.73
1.21
1.1
1.4
—
—
—
0
0
16
93
1.73
1.21
1.1
1.4
—
—
—
0
0
16
94
1.71
1.18
1.1
1.4
—
—
—
0
0
613
6411
0.88
1.17
7.7
7.2
40.40
40.41
mmol/mol
0.01
572
5877
53
404
1.33
1.17
2.7
2.5
4.12
4.19
g/l
0.31
44
361
53
404
1.33
1.17
2.7
2.5
7.72
7.58
g/l
0.22
44
361
17
102
1.68
1.16
2.1
2.9
56.50
23.73
mg/l
—
6
40
10
50
2.01
1.16
1.6
1.8
88.38
88.37
ng/l
—
10
50
10
50
2.01
1.16
1.1
1.1
—
117.50
—
0
8
209
1853
1.16
1.14
1.8
1.8
68750457.84
11126365.12
pmol/l
0.39
176
1501
49
371
1.34
1.13
2.3
2.6
3.05
3.12
g/l
0.15
39
328
7
30
2.34
1.12
1.1
1.1
—
—
—
0
0
8
40
2.01
1.12
1.1
1.2
—
—
—
0
0
680
7054
0.87
1.11
18.1
12.5
23.91
24.24
u/l
0.22
663
6795
511
5396
0.88
1.10
36.3
25.8
329.93
330.66
g/l
0.90
506
5345
596
5678
1.13
1.10
12.6
8.0
84.87
81.46
u/l
0.71
571
5323
45
589
0.75
1.08
1.3
1.7
1.57
1.55
%
0.05
35
505
631
6572
0.88
1.07
5.8
5.5
6.01
6.08
mmol/l
0.66
565
5878
284
2587
1.14
1.07
1.9
1.8
18.17
20.65
nmol/l
1.93
245
2147
52
403
1.31
1.04
2.7
2.5
3.77
3.76
g/l
0.01
43
361
200
1782
1.16
1.03
6.4
4.9
1.02
1.02
kg/l
0.06
141
1211
7
34
2.07
1.03
2.0
1.1
—
—
—
0
0
96
803
1.22
1.02
3.7
3.4
227.93
268.05
ng/l
0.38
91
741
331
3053
1.13
1.02
6.4
4.3
218.57
142.48
e6/l
0.21
244
2225
9
49
1.84
0.98
2.9
2.4
—
—
—
0
0
300
2756
1.13
0.98
5.3
3.7
92.78
93.66
e6/l
0.01
239
2153
9
51
1.77
0.94
1.1
1.2
—
—
—
0
0
9
51
1.77
0.94
1.1
1.2
—
—
—
0
0
260
2373
1.13
0.94
4.9
3.5
0.41
0.55
e6/l
0.33
207
1800
356
3318
1.12
0.90
5.2
4.4
36.28
88.97
ng/l
1.32
289
2595
23
160
1.45
0.89
1.1
1.1
—
11.10
—
0
11
698
7195
0.89
0.89
36.5
25.9
85.85
83.16
umol/l
0.78
687
7079
13
80
1.63
0.85
1.4
1.2
14.54
14.71
u/l
0.01
13
72
10
57
1.76
0.84
1.6
1.1
—
—
—
0
0
19
129
1.48
0.84
1.4
1.3
—
—
—
0
0
16
237
0.67
0.82
1.2
1.4
0.18
0.33
mg/l
—
7
98
20
138
1.46
0.82
1.6
1.3
—
—
—
0
0
81
685
1.20
0.81
4.5
3.9
1.22
1.22
mmol/l
0.06
75
584
6
33
1.82
0.79
1.3
1.1
—
—
—
0
0
6
33
1.82
0.79
1.2
1.0
—
—
—
0
0
12
74
1.63
0.78
1.2
1.6
—
—
—
0
0
5
100
0.50
0.77
1.8
1.8
197.60
227.32
pmol/l
—
5
91
195
1771
1.13
0.77
1.9
1.8
1179.74
1196.23
nmol/l
0.10
152
1313
612
6333
0.90
0.77
5.9
5.5
1.96
2.01
mu/l
0.43
557
5708
6
34
1.77
0.76
2.7
2.3
—
—
—
0
0
526
5482
0.91
0.76
32.7
23.9
14.22
13.94
%
3.44
521
5400
0
28
0.00
0.76
0.0
1.5
—
173.37
—
0
28
373
3513
1.10
0.76
2.9
2.6
—
—
—
0
0
26
192
1.36
0.75
3.5
4.1
54.04
28.91
mg/l
1.44
20
141
5
24
2.09
0.74
1.2
1.2
—
—
—
0
0
18
125
1.45
0.73
1.7
1.5
—
—
—
0
0
9
56
1.61
0.72
1.7
1.2
—
—
—
0
0
353
3324
1.10
0.71
4.0
3.1
163.62
136.89
ug/l
1.11
323
3028
18
126
1.44
0.70
1.7
1.8
—
—
—
0
0
40
319
1.27
0.70
4.6
3.6
1.41
1.43
mmol/l
0.03
40
313
7
43
1.63
0.67
1.3
1.8
16.87
14.85
umol/l
—
7
38
180
1644
1.12
0.66
2.0
1.6
2.32
1.48
mg/l
0.75
145
1298
97
853
1.15
0.64
1.6
1.5
—
—
—
0
0
8
49
1.64
0.62
1.3
2.0
—
—
—
0
0
8
49
1.64
0.62
1.8
1.2
—
—
—
0
0
5
30
1.67
0.61
1.4
1.3
—
—
—
0
0
5
30
1.67
0.61
2.2
2.4
44.71
47.34
umol/l
—
5
25
8
51
1.57
0.60
1.8
1.2
—
—
—
0
0
8
51
1.57
0.60
1.8
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
11
73
1.51
0.56
1.6
1.5
—
57.14
—
0
7
162
1487
1.11
0.55
1.3
1.3
2.45
1.31
u/ml
0.53
46
363
35
285
1.24
0.54
3.3
3.6
0.79
0.83
nmol/l
0.24
30
240
8
125
0.64
0.54
1.0
1.2
0.84
0.91
g/l
—
8
125
9
60
1.50
0.54
1.6
1.2
83.00
97.93
pmol/l
—
9
60
308
2923
1.08
0.51
3.1
3.3
2.34
2.35
mmol/l
1.34
273
2593
221
2071
1.09
0.50
4.9
4.0
0.30
0.07
estimate
0.34
83
665
7
45
1.56
0.49
1.4
1.6
—
—
—
0
0
7
49
1.43
0.46
1.9
1.2
—
—
—
0
0
695
7085
0.93
0.45
32.9
24.0
4.01
4.01
mmol/l
0.19
681
6914
158
1467
1.09
0.45
4.3
3.2
1.19
1.29
e6/l
0.15
97
812
15
112
1.34
0.45
1.8
1.2
157551.11
90765.92
e6/l
—
9
59
9
128
0.70
0.43
1.2
1.8
46.00
43.26
nmol/l
—
9
120
104
948
1.11
0.43
11.2
8.9
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
12
87
1.38
0.42
1.1
1.1
—
23.47
—
0
18
5
32
1.57
0.42
1.0
1.0
140.80
530.85
u/l
—
5
26
5
33
1.52
0.41
1.6
1.2
—
—
—
0
0
695
7075
0.93
0.40
32.7
23.9
139.25
139.54
mmol/l
1.86
682
6916
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
100
916
1.10
0.38
4.7
5.2
34.19
32.92
%
0.53
68
551
518
5316
0.94
0.38
4.8
4.3
15.50
15.08
pmol/l
3.11
471
4739
19
236
0.80
0.38
1.4
1.2
—
—
—
0
0
19
235
0.80
0.37
1.4
1.2
—
—
—
0
0
18
143
1.26
0.37
1.3
1.1
—
4.98
—
0
12
17
213
0.79
0.37
1.5
1.3
—
—
—
0
0
17
213
0.79
0.37
1.5
1.3
—
—
—
0
0
10
72
1.39
0.37
2.2
1.3
718.40
150694.04
e6/l
—
5
51
6
44
1.37
0.34
1.5
1.2
36.17
24.54
u/l
—
6
37
6
44
1.37
0.34
2.2
4.3
1.00
0.77
%
—
6
44
6
46
1.31
0.33
1.2
1.5
—
—
—
0
0
6
46
1.31
0.33
1.2
1.5
—
—
—
0
0
6
47
1.28
0.32
1.7
1.4
—
—
—
0
0
19
157
1.21
0.29
2.2
1.8
—
—
—
0
0
7
57
1.23
0.29
1.0
1.0
—
—
—
0
0
101
942
1.08
0.29
3.4
3.9
43.64
26.01
ug/l
0.21
84
785
30
344
0.87
0.28
2.6
3.2
443.77
9056.05
u/ml
0.59
23
291
8
64
1.25
0.27
1.8
1.1
—
—
—
0
0
10
77
1.30
0.26
1.0
1.1
—
1.68
—
0
10
144
1369
1.06
0.25
4.8
3.4
4.16
2.46
e6/l
0.82
82
716
180
1723
1.06
0.25
4.9
4.4
443.05
252.54
ng/l
0.49
155
1475
635
6436
0.96
0.23
26.5
19.2
72.00
72.39
ml/min/173m2
0.16
595
6014
28
247
1.14
0.23
1.5
1.4
290.11
273.14
ug/g
0.15
17
144
269
2610
1.04
0.22
4.0
3.3
6.37
6.90
mmol/l
1.52
230
2152
73
781
0.93
0.22
1.2
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
22.20
—
0
10
0
12
0.00
0.21
0.0
1.0
—
0.20
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.20
0.19
1.7
1.4
—
—
—
0
0
192
1857
1.04
0.18
4.4
4.8
20.73
21.99
%
0.57
92
970
12
100
1.20
0.18
1.7
1.3
—
—
—
0
0
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
13
110
1.18
0.17
1.5
1.5
—
—
—
0
0
8
68
1.18
0.16
1.8
1.6
—
—
—
0
0
93
887
1.05
0.16
4.5
3.8
—
—
—
0
0
13
111
1.17
0.16
1.0
1.3
161.60
209.74
miu/ml
—
5
50
31
337
0.92
0.14
3.6
1.8
—
—
—
0
0
20
223
0.89
0.14
3.4
3.2
7.70
7.70
mmol/l
0.00
20
217
37
343
1.08
0.14
2.2
2.8
1.25
1.14
g/l
0.04
30
294
28
305
0.92
0.14
3.4
1.8
—
—
—
0
0
12
103
1.17
0.13
5.8
5.0
367.08
344.69
umol/l
0.27
12
94
128
1323
0.96
0.13
3.2
3.4
0.62
0.84
ug/l
2.97
86
909
24
260
0.92
0.11
3.3
3.2
1.35
1.66
mmol/l
1.69
24
253
39
368
1.06
0.10
1.2
1.2
151.10
134.54
u/ml
—
10
128
5
46
1.09
0.09
11.4
3.2
1.20
0.85
index
—
5
46
6
55
1.09
0.09
1.7
1.4
—
—
—
0
0
32
302
1.06
0.08
1.3
1.3
—
—
—
0
0
30
283
1.06
0.08
1.0
1.0
—
—
—
0
0
7
67
1.05
0.08
1.3
1.2
—
—
—
0
0
12
108
1.11
0.07
1.8
1.5
—
—
—
0
0
7
82
0.85
0.07
2.9
2.7
—
—
—
0
0
14
152
0.92
0.06
5.8
2.7
9.04
9.81
pmol/l
0.09
14
152
267
2642
1.01
0.06
4.7
4.1
17.34
9.34
mg/mmol
0.92
171
1650
234
2315
1.01
0.05
5.4
6.0
3.26
5.18
ug/l
0.47
207
2031
183
1852
0.99
0.05
2.9
3.1
2.47
2.47
mmol/l
0.03
164
1648
76
744
1.02
0.04
3.3
2.4
39.94
33.72
u/l
0.35
67
612
20
190
1.05
0.04
2.2
2.4
37.13
73.53
ug/min
1.17
12
113
11
102
1.08
0.03
2.5
1.5
—
—
—
0
0
23
223
1.03
0.01
5.5
3.6
0.93
2.05
index
0.97
15
117
374
3732
1.00
0.01
2.5
2.3
90.44
94.49
pmol/l
1.00
208
1920
15
144
1.04
0.00
1.5
1.4
24.84
27.80
iu/l
—
10
113
684
6846
1.00
0.00
29.7
19.4
27.57
27.38
mg/l
0.05
617
5839
14
138
1.01
0.00
1.2
1.5
—
—
—
0
0
424
4238
1.00
0.00
4.7
3.3
65.61
53.73
u/l
1.05
398
3881
16
159
1.01
0.00
1.4
1.8
2.40
38.42
iu/l
—
7
67
7
69
1.01
0.00
1.1
1.2
1.38
1.59
nmol/l
—
7
60
7
78
0.90
-0.00
2.0
2.3
706.86
930.97
mg
—
7
78
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
92
0.98
-0.00
1.2
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TUBERCU_OTH_ORG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_TUBERCU_OTH_ORG | 1.523 [1.36, 1.71] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.42 |
During the follow-up period (1.1.1998 — 31.12.2019), 693 out of 1730 females with AB1_TUBERCU_OTH_ORG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_TUBERCU_OTH_ORG | 1.85 [1.57, 2.18] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 588 out of 1311 males with AB1_TUBERCU_OTH_ORG died.
Mortality risk
Mortality risk for people of age
years, who have AB1_TUBERCU_OTH_ORG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.092% | 0.383% |
| 5 | 0.859% | 2.039% |
| 10 | 2.049% | 5.092% |
| 15 | 4.14% | 9.389% |
| 20 | 7.541% | 15.862% |
Relationships between endpoints
↥Index endpoint: AB1_TUBERCU_OTH_ORG – Tuberculosis of other organs, strict
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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