Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution
3013650	b-neut	e9/l (e9/l)	209753	1605092	0.06%
3013650	b-neut	— (—)	91425	547931	100.00%	Distribution not available
3013650	b-neu	e9/l (e9/l)	1174	3658	0.00%

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Visual disturbances

14108

110357

1.71

323.31

10.0

9.0

4.08

4.11

e9/l

0.80

12435

96308

Dental caries 3, only avohilmo

29171

123964

1.43

323.31

9.1

8.7

4.15

4.12

e9/l

1.08

25464

108042

Noninfectious colitis NAS

4213

26645

3.03

322.83

14.5

8.7

4.18

4.08

e9/l

2.45

3829

23155

Diagnoses used for exclusion with ILD

7435

52544

2.13

322.61

12.4

8.9

4.35

4.20

e9/l

5.99

6783

45582

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

30887

169090

1.41

320.94

10.3

8.9

4.07

4.14

e9/l

4.46

27258

147709

Viral pneumonia

3836

23572

3.12

320.87

15.8

8.0

4.59

4.00

e9/l

33.61

3410

20375

Disorders of conjunctiva

26456

184567

1.45

320.87

9.1

9.0

3.98

4.06

e9/l

6.67

23185

161759

Cholelithiasis

26553

154726

1.45

319.49

9.1

8.7

4.37

4.07

e9/l

62.36

23453

134862

Artrosis, including avohilmo

28161

128197

1.43

317.68

8.2

9.7

4.14

4.13

e9/l

0.15

24725

112258

Gout, unspecified

5498

37017

2.52

317.55

10.6

8.8

4.94

4.34

e9/l

48.41

4828

32045

Parodontitis or operation codes

28360

175284

1.44

317.28

10.5

9.0

4.27

4.09

e9/l

27.26

24686

153643

Dental pulpitis 1, only avohilmo

38471

171719

1.36

316.52

9.4

8.7

4.19

4.07

e9/l

17.32

33539

150255

Diseases of arteries, arterioles and capillaries

19316

116304

1.56

315.86

9.8

9.1

4.67

4.17

e9/l

115.98

16986

100800

Accidents

30546

127615

1.40

315.66

9.1

8.9

4.15

4.04

e9/l

11.80

26574

112164

Parodontitis

28321

175245

1.44

315.65

10.5

9.0

4.27

4.09

e9/l

27.28

24648

153609

Cutaneous abscess, furuncle and carbuncle

7687

55027

2.10

315.31

13.4

8.9

4.51

4.06

e9/l

43.57

6877

48125

Myeloproliferative diseases

2635

15131

5.34

314.19

22.2

8.6

5.21

4.18

e9/l

21.21

2468

13129

Continuous positive airway pressure

5770

32999

2.26

314.07

10.7

9.0

4.60

3.81

e9/l

101.13

4983

28450

Oter anti-inflammatory and antirheumatic agents, non-steroids

7127

26599

2.01

312.89

8.7

10.4

4.20

4.36

e9/l

6.00

6270

23101

Benign neoplasm of other and ill-defined parts of digestive system

4790

31120

2.61

312.87

10.8

6.4

4.25

e9/l

0.03

4264

26639

Chronic periodontitis, including avohilmo

28184

175165

1.44

312.14

10.5

9.0

4.27

4.09

e9/l

27.24

24525

153548

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

6588

43070

2.37

307.65

10.6

6.5

3.68

4.08

e9/l

44.01

5732

36764

Spondylopathies (FG)

5250

27601

5.56

307.65

13.0

8.6

3.89

4.05

e9/l

7.77

4975

23912

Seropositive rheumatoid arthritis, strict definition

5842

30638

12.70

307.65

18.4

8.6

3.96

4.05

e9/l

2.95

5575

26590

Implicit bacterial Sepsis

12359

74686

2.51

307.65

15.2

8.1

4.95

4.18

e9/l

149.46

11207

64244

Seronegative rheumatoid arthritis

4305

22525

6.68

307.65

16.9

8.3

3.99

4.05

e9/l

1.16

4046

19307

Other (seronegative) rheumatoid arthritis, wide

6752

39427

4.92

307.65

16.5

8.7

4.09

4.11

e9/l

0.28

6328

34221

Benzodiazepine use

35305

194664

1.69

307.65

12.4

8.4

4.26

4.09

e9/l

31.41

31089

170225

Other arthrosis

16697

87904

1.85

307.65

8.6

9.1

4.05

4.15

e9/l

5.14

14628

75969

Diseases of liver

10223

73458

2.13

307.65

12.3

9.2

4.11

4.13

e9/l

0.23

9154

64043

Coxarthrosis

15002

77857

1.66

307.65

8.6

9.0

4.22

4.19

e9/l

0.75

13154

67030

Crohn disease (strict definition, require KELA, min 2 HDR)

2395

11878

15.39

307.65

20.1

9.0

3.94

4.00

e9/l

0.88

2312

10469

Other respiratory diseases principally affecting the interstitium

5123

32750

2.92

307.65

15.3

8.5

4.79

4.29

e9/l

36.86

4746

28243

Psoriasis vulgaris

6050

38298

3.20

307.65

13.8

9.2

4.13

4.10

e9/l

0.61

5617

33380

Other diseases of blood and blood-forming organs, wide

7586

45306

4.44

307.65

24.8

8.7

3.84

4.11

e9/l

11.25

7117

39325

Other and unspecified iron deficiency

10500

68914

2.70

307.65

11.6

8.5

4.34

4.16

e9/l

11.37

9420

59692

Other and unspecified anaemias

13457

83751

2.76

307.65

15.1

8.3

4.24

4.28

e9/l

0.81

12133

72114

Agranulocytosis

3583

21289

4.81

307.65

32.6

8.7

2.96

4.06

e9/l

195.92

3418

18489

Viral Sepsis

6044

37266

3.15

307.65

15.8

8.1

4.57

4.12

e9/l

30.82

5526

32106

Depression

35171

181232

1.84

307.65

10.2

8.7

4.14

4.05

e9/l

11.41

30669

159135

Psoriasis

9770

62129

3.19

307.65

13.6

9.1

4.11

4.08

e9/l

0.71

9008

54107

Explicit Sepsis

14099

89504

2.51

307.65

17.1

8.1

4.79

4.13

e9/l

124.48

12862

77171

Other Crohn's disease

2648

13094

12.20

307.65

20.5

8.7

3.96

4.01

e9/l

0.68

2550

11484

15428

103082

2.41

307.65

10.4

9.0

4.43

4.03

e9/l

90.60

13899

89744

Autoimmune diseases excluding thyroid diseases

46856

156316

3.05

307.65

13.3

7.6

4.07

4.14

e9/l

6.84

43085

134294

Hernia of abdominal wall, postoperative

5682

32095

3.38

307.65

11.5

6.4

4.43

4.02

e9/l

30.00

5126

27327

Disorders of eyelid, lacrimal system and orbit

27921

172221

1.66

307.65

9.7

8.9

4.07

4.13

e9/l

3.35

24701

150260

Dermatitis and eczema

39684

198672

1.75

307.65

10.0

8.8

4.09

4.10

e9/l

0.73

35518

173026

Asthma (only as main-diagnosis), excluding more controls

27936

105414

2.50

307.65

8.9

7.6

4.31

3.87

e9/l

164.06

25080

91019

Schizophrenia or delusion, excluding more controls

10542

67096

2.60

307.65

26.2

8.1

4.40

3.99

e9/l

61.89

9458

58874

Dental caries 3

28901

121213

1.46

307.65

9.4

8.4

4.15

4.11

e9/l

1.69

25255

105510

Bronchitis

37367

196271

1.56

307.65

11.7

8.4

4.28

4.07

e9/l

53.45

33486

170820

Other diseases of intestines

41706

171972

2.03

307.65

10.6

8.5

4.17

4.06

e9/l

16.97

37013

149940

Cardiovascular diseases (excluding rheumatic etc)

24587

102719

1.88

307.65

10.9

8.4

4.14

3.84

e9/l

76.48

21892

90050

Chronic rhinitis, nasopharyngitis and pharyngitis

10116

72492

2.10

307.65

8.9

9.4

3.95

4.02

e9/l

3.29

8807

63421

Bacterial Sepsis

14390

85345

2.44

307.65

15.3

8.2

4.90

4.16

e9/l

165.21

13022

73458

Noninfective enteritis and colitis

17716

110231

3.18

307.65

14.0

8.7

4.04

4.09

e9/l

1.99

16279

95994

41886

172957

1.63

307.65

11.0

8.2

4.25

4.04

e9/l

53.53

37443

150075

Psoriatic arthropathies

3875

19133

9.11

307.65

15.6

9.2

3.89

4.07

e9/l

6.47

3704

16594

Rotator cuff syndrome

19413

113835

1.62

307.65

8.3

9.4

4.09

4.13

e9/l

1.26

17209

98971

All pneumoniae

38029

187457

2.06

307.65

14.0

8.1

4.60

3.96

e9/l

307.65

34057

163207

Spinal stenosis

15446

90797

1.81

307.65

8.4

9.2

4.36

4.18

e9/l

14.60

13650

78138

Atrial fibrillation and flutter

10792

47353

2.21

307.65

10.1

9.0

4.29

3.78

e9/l

85.53

9412

41198

Arthrosis

24287

102510

1.64

307.65

8.4

9.0

4.14

4.15

e9/l

0.22

21427

88732

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

6141

33779

5.69

307.65

15.4

9.1

3.89

4.06

e9/l

9.77

5744

29587

Paralytic ileus and intestinal obstruction

7590

51088

2.30

307.65

15.0

8.6

4.50

4.21

e9/l

15.24

6848

44032

Polyarthropathies

30974

112788

4.26

307.65

13.9

8.8

4.17

4.13

e9/l

2.05

28587

97628

Influenza and pneumonia

40251

189309

2.04

307.65

13.8

8.0

4.55

3.95

e9/l

307.65

36091

164794

Non-allergic asthma (mode), excluding more controls

6229

39050

2.53

307.65

8.9

7.5

4.36

3.87

e9/l

54.29

5610

33387

Colorectal cancer, excluding all cancers (controls excluding all cancers)

7966

48057

2.74

307.65

15.9

6.2

3.98

4.37

e9/l

37.22

7001

40881

Crohn's disease NAS

2316

12143

7.51

307.65

20.0

8.8

4.01

4.02

e9/l

0.02

2225

10641

Temporomandibular joint disorders

5218

32748

2.62

307.65

10.2

8.6

3.84

3.88

e9/l

0.64

4808

28459

Any mental disorder

41679

162910

1.63

307.65

10.7

8.3

4.23

4.04

e9/l

43.59

36473

142582

Septicaemia

13402

82578

2.70

307.65

17.5

7.5

4.81

4.12

e9/l

126.82

12230

70936

Bleeding

26210

151177

1.61

307.65

10.7

9.1

4.40

4.11

e9/l

57.65

23315

131257

Other functional intestinal disorders

14785

97503

2.17

307.65

11.8

8.6

4.16

4.10

e9/l

2.62

13248

84313

All anxiety disorders

22137

128210

2.01

307.65

10.7

8.5

4.11

3.99

e9/l

12.15

19231

112973

Non-invasive ventilation

7140

42080

2.61

307.65

11.6

8.4

4.53

3.80

e9/l

97.84

6824

36629

Implicit viral Sepsis

6030

37177

3.15

307.65

15.8

8.1

4.57

4.12

e9/l

30.96

5514

32028

Nerve, nerve root and plexus disorders

35994

183017

1.53

307.65

8.7

9.1

4.19

4.11

e9/l

6.44

32079

159584

Irritable bowel syndrome

8789

61333

2.21

307.65

8.5

3.92

4.00

e9/l

3.68

7815

53458

Asthma, hospital admission 2, infections

20739

139176

2.32

307.65

10.5

8.9

4.55

4.07

e9/l

140.25

18676

121048

Chronic sinusitis

13840

102970

1.88

307.65

9.2

9.3

4.13

4.07

e9/l

2.52

12211

90211

Other headache syndromes

14017

103291

1.93

307.65

8.3

9.1

4.04

4.01

e9/l

0.85

12470

90318

Asthma, hospital admissions , main diagnosis only

29559

196845

1.87

307.65

8.8

9.0

4.31

4.06

e9/l

64.31

26499

171685

Any operation in hilmo

1831

3145

4.39

307.65

8.9

4.9

4.09

3.77

e9/l

5.01

1598

2730

Unspecified haematuria

11938

77163

1.78

307.65

10.4

8.9

4.45

4.23

e9/l

15.67

10370

66990

Rheumatoid arthritis

13768

64413

6.31

307.65

16.5

8.7

4.04

4.12

e9/l

4.15

12952

55540

Excluding asthma or asthma-COPD overlap

32358

111534

2.05

307.65

10.5

7.6

4.21

3.91

e9/l

79.98

28666

96280

Asthma, hospital admissions 3, pneumonia

11516

76382

2.47

307.65

12.4

8.8

4.84

4.15

e9/l

134.18

10424

65977

Obesity

19421

152787

1.64

307.65

9.3

9.0

4.60

4.00

e9/l

243.36

17084

134155

Asthma (mode)

31562

111207

2.44

307.65

9.0

7.6

4.28

3.91

e9/l

136.49

28116

96015

Any event in cancer register

35851

143961

2.30

307.65

14.8

7.0

3.88

4.15

e9/l

75.86

32366

124469

Lumbar disc prolapse

20449

128143

1.61

307.65

8.3

9.3

4.10

4.09

e9/l

0.24

18237

111406

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

5216

32636

2.67

307.65

16.5

6.1

3.92

4.43

e9/l

46.59

4747

27711

Benign neoplasm: Colon

15582

114136

1.94

307.65

10.1

9.1

4.27

4.21

e9/l

2.15

13641

99016

Any reimbursement code in KELA

26167

70806

3.15

307.65

13.0

3.0

4.01

3.93

e9/l

5.95

23555

59851

Asthma-related pneumonia or sepsis

11516

76382

2.47

307.65

12.4

8.8

4.84

4.15

e9/l

134.18

10424

65977

Hypertension, essential

27830

116334

1.88

307.65

10.3

9.1

4.37

3.89

e9/l

183.70

24561

102001

Dermatitis

20607

148408

2.08

307.65

11.3

8.9

4.14

4.10

e9/l

1.13

18763

129232

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

11519

54379

4.14

307.65

13.0

6.6

3.46

4.02

e9/l

159.52

10674

46809

Use of hypnotics and sedatives

37264

172146

1.57

307.65

11.3

8.6

4.19

4.10

e9/l

10.36

32856

150486

Bipolar affective disorders

6098

40607

2.46

307.65

11.6

8.5

4.22

3.97

e9/l

13.35

5312

35854

Pain (limb, back, neck, head abdominally)

29269

101780

1.96

307.65

9.4

8.8

4.16

4.04

e9/l

10.28

25775

87868

Gout

8261

46276

2.79

307.65

12.1

8.8

4.80

4.39

e9/l

31.45

7305

39666

Acute upper respiratory infections of multiple and unspecified sites

25443

148990

1.63

307.65

12.0

8.4

4.17

4.05

e9/l

11.92

22837

129880

Hypothyroidism, drug reimbursement

5104

19206

3.15

307.65

9.7

4.9

3.93

3.86

e9/l

1.38

4542

16794

Interstitial lung disease endpoints

4424

27267

3.46

307.65

15.5

8.6

4.74

4.29

e9/l

28.25

4105

23577

Episodal and paroxysmal disorders

41898

167732

1.62

307.65

8.6

9.1

4.15

4.07

e9/l

8.16

36939

146161

Asthma-related pneumonia

11495

76203

2.47

307.65

12.4

8.8

4.84

4.15

e9/l

135.11

10407

65830

Metabolic disorders

34124

155935

1.89

307.65

10.9

8.9

4.35

4.03

e9/l

94.82

29752

136544

Malignant neoplasm of breast, HER2-negative

16881

82365

2.83

307.65

12.3

8.6

3.53

4.02

e9/l

168.91

15491

71264

Diseases of oesophagus, stomach and duodenum

39299

177653

1.84

307.65

9.8

8.9

4.15

4.10

e9/l

3.82

35033

154783

Other disorders of skin and subcutaneous tissue

22068

152738

1.84

307.65

10.8

8.9

4.28

4.12

e9/l

18.65

19792

132798

Depression or dysthymia

25895

106673

1.81

307.65

7.9

8.6

4.13

4.05

e9/l

5.82

22623

93220

Soft tissue disorders

39238

156692

1.67

307.65

8.8

9.0

4.11

4.10

e9/l

0.57

34786

136261

Chronic lower respiratory diseases

45727

187468

1.76

307.65

9.1

9.0

4.37

4.01

e9/l

167.13

40748

163227

STROKE

18035

99638

1.60

307.65

9.4

9.5

4.32

3.93

e9/l

72.14

15915

86520

Asthma and allergy

4416

26996

2.63

307.65

7.7

7.5

4.06

3.82

e9/l

12.20

3923

23431

Infections of the skin and subcutaneous tissue

18728

140168

1.84

307.65

12.4

8.9

4.37

4.07

e9/l

49.00

16700

122547

Heart failure, strict

16700

92071

1.76

307.65

10.4

9.0

4.96

4.18

e9/l

222.27

14872

79344

Anxiety disorders, excluding more controls

30963

148181

1.97

307.65

11.2

8.2

4.09

4.00

e9/l

9.53

27150

130001

Asthma/COPD (KELA code 203)

34021

186698

1.65

307.65

8.5

9.0

4.40

4.01

e9/l

145.98

30414

162568

Antihypertensive medication - note that there are other indications

23340

93752

1.79

307.65

11.1

8.1

4.19

3.81

e9/l

113.83

20782

82132

Pure hypercholesterolaemia

23709

119931

1.80

307.65

9.3

9.0

4.41

4.07

e9/l

73.17

20197

104601

Dorsopathies

39386

153855

1.68

307.65

8.7

9.0

4.11

4.09

e9/l

1.07

34942

133641

Mood [affective] disorders

38035

187772

1.82

307.65

10.5

8.7

4.16

4.06

e9/l

11.47

33184

164733

Type 2 diabetes, wide definition

25278

131914

1.57

307.65

10.8

9.1

4.75

3.96

e9/l

307.65

22059

114982

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

16180

64518

3.33

307.65

12.3

6.6

3.50

4.01

e9/l

170.70

14681

55817

Malignant neoplasm of breast, HER-positive

11389

72510

3.39

307.65

13.0

8.8

3.46

4.01

e9/l

155.45

10574

62684

Other disorders of urethra and urinary system

23400

134856

1.71

307.65

10.3

8.4

4.24

4.07

e9/l

19.39

20702

117786

Other joint disorders

33521

132001

1.78

307.65

8.4

8.6

4.05

4.10

e9/l

4.28

29732

114401

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

16179

64507

3.33

307.65

12.3

6.6

3.50

4.01

e9/l

170.77

14680

55807

Diaphragmatic hernia

10775

78675

2.06

307.65

10.0

9.1

4.19

4.14

e9/l

1.44

9382

68201

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

15221

79881

1.66

307.65

10.1

6.5

4.11

4.25

e9/l

9.05

13275

68355

Gastro-oesophageal reflux disease

22808

151149

1.86

307.65

9.0

4.08

4.10

e9/l

0.79

20352

131506

Acute tubulo-interstitial nephritis

20083

133859

1.82

307.65

11.9

8.2

4.68

4.05

e9/l

185.53

17763

116078

Asthma, excluding more controls

31512

105414

2.56

307.65

9.2

7.6

4.32

3.87

e9/l

188.82

28118

91019

Malignant neoplasm of breast

17523

83306

2.89

307.65

12.2

8.5

3.53

4.02

e9/l

175.16

15984

72165

Other diseases of anus and rectum

8685

62470

1.98

307.65

10.3

8.6

4.19

4.16

e9/l

0.58

7659

53960

Shoulder lesions

25993

125074

1.62

307.65

8.3

9.3

4.08

4.13

e9/l

2.73

23104

108824

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

13496

67877

2.53

307.65

17.2

6.5

4.12

4.31

e9/l

12.72

12003

57899

Other systemic involvement of connective tissue (FG)

9445

53080

4.23

307.65

11.9

8.0

4.19

4.09

e9/l

4.22

8726

45486

Disorders of sclera, cornea, iris and ciliary body

16676

131743

1.65

307.65

10.4

9.1

4.09

4.10

e9/l

0.36

15046

115092

Spondylopathies

28828

124584

2.01

307.65

9.4

9.3

4.18

4.12

e9/l

3.59

25935

107977

Sleep disorders (combined)

33922

177758

1.59

307.65

8.4

9.3

4.24

4.07

e9/l

32.02

29910

155617

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

5004

25720

6.56

307.65

23.3

6.5

3.78

4.29

e9/l

45.74

4740

22051

Substance use, excluding alcohol

6287

41130

2.64

307.65

15.6

9.0

4.61

3.99

e9/l

73.72

5610

36123

Recurrent or chronic depression

14674

72633

2.12

307.65

7.4

8.4

4.02

3.92

e9/l

7.06

12851

63903

Inflammatory bowel disease, strict (require KELA)

9360

51179

5.83

307.65

16.2

9.0

3.90

4.04

e9/l

11.03

8803

44812

Renal tubulo-interstitial diseases

30915

170817

2.04

307.65

12.9

8.3

4.64

4.03

e9/l

288.84

27557

148571

Other soft tissue disorders, not elsewhere classified

36056

153771

2.19

307.65

9.7

9.0

4.16

4.10

e9/l

4.65

31971

133764

Allergic asthma (mode)

8198

53078

2.26

307.65

7.9

7.5

4.18

3.86

e9/l

29.37

7293

46020

Other septicaemia

11838

74115

2.71

307.65

17.8

7.4

4.82

4.13

e9/l

109.87

10835

63591

COPD/asthma/ILD related infections

40424

151012

1.80

307.65

11.5

7.7

4.32

3.94

e9/l

154.98

36079

130854

Acute upper respiratory infections

36672

184567

1.55

307.65

10.8

8.5

4.16

4.08

e9/l

6.76

32763

160544

Arthropathies

35889

132430

1.85

307.65

9.4

8.6

4.05

4.10

e9/l

3.94

32108

114750

Other/unspecified dorsalgia

12161

86097

2.03

307.65

9.8

9.0

4.19

4.09

e9/l

4.48

10781

74652

Other heart diseases

17724

80390

2.13

307.65

10.8

8.7

4.18

3.80

e9/l

88.32

15713

70348

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

5730

30446

5.56

307.65

27.8

6.3

4.06

4.31

e9/l

10.56

5409

26009

COPD (mode)

9223

49206

2.22

307.65

10.6

7.6

5.19

4.02

e9/l

263.85

8178

41909

Coxarthrosis [arthrosis of hip](FG)

16043

90077

1.63

307.65

8.6

8.5

4.22

4.15

e9/l

2.98

14059

77260

Benign neoplasm of colon, rectum, anus and anal canal

18998

127575

1.94

307.65

10.0

9.1

4.25

4.19

e9/l

2.99

16604

110800

Renal failure

13651

82793

2.51

307.65

13.8

8.6

4.91

4.26

e9/l

131.82

12346

71324

Dorsalgia

38538

152103

1.88

307.65

8.9

9.0

4.15

4.10

e9/l

4.69

34238

132151

Cystitis

30280

143122

1.69

307.65

9.5

8.4

4.16

4.07

e9/l

8.49

26506

125064

Cardiac arrhythmias

22087

108245

1.83

307.65

9.3

8.9

4.09

3.83

e9/l

48.94

19464

94998

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

7856

40839

6.52

307.65

28.7

6.3

4.09

4.32

e9/l

13.14

7400

34902

Primary_lymphoid and hematopoietic malignant neoplasms

8212

42701

5.50

307.65

28.7

6.4

3.50

4.32

e9/l

140.75

7679

36401

Asthma-related infections

20739

139176

2.32

307.65

10.5

8.9

4.55

4.07

e9/l

140.25

18676

121048

35159

150788

2.23

307.65

14.0

7.7

4.60

3.94

e9/l

307.65

31526

130663

Other reaction to severe stress, and adjustment disorders

12225

87359

2.05

307.65

12.5

8.4

4.08

3.97

e9/l

5.15

10909

77003

COPD differential diagnosis

32145

111236

2.04

307.65

10.5

7.6

4.20

3.91

e9/l

74.51

28483

96041

Disorders of lipoprotein metabolism and other lipidaemias

27504

131288

1.76

307.65

9.4

9.0

4.39

4.05

e9/l

81.99

23569

114681

Chronic kidney disease

8902

56359

2.76

307.65

13.4

8.3

4.83

4.30

e9/l

62.74

8132

48405

Diarrhoea and gastroenteritis of presumed infectious origin

23978

165652

1.75

307.65

12.0

8.4

4.31

4.08

e9/l

38.06

21528

144324

Pulmonary embolism

8281

59502

2.06

307.65

14.7

8.6

4.42

4.21

e9/l

8.89

7397

51462

Autoimmune diseases

46855

157622

2.35

307.65

12.0

7.6

4.05

4.13

e9/l

12.20

42547

135403

Erysipelas

17676

113525

2.09

307.65

12.1

7.7

4.65

4.08

e9/l

139.55

15699

97893

Atrial fibrillation and flutter with reimbursement

8702

36376

2.40

307.65

9.2

9.1

4.41

3.78

e9/l

95.47

7485

31462

Mucosal proctocolitis

4869

25503

7.12

307.65

17.1

8.9

3.92

4.06

e9/l

5.56

4582

22309

Migraine

16530

106313

1.79

307.65

8.0

8.9

3.95

3.93

e9/l

0.51

14743

93202

Other bacterial diseases

36638

166887

2.54

307.65

16.2

7.8

4.56

4.00

e9/l

263.02

33025

144719

Polyarthrosis

6239

37356

2.98

307.65

9.5

8.8

4.01

4.09

e9/l

2.22

5689

31997

Gonarthrosis

21195

93152

1.65

307.65

8.4

9.0

4.17

4.16

e9/l

0.40

18636

80500

Heart failure,strict

15587

82543

1.95

307.65

10.7

8.9

4.96

4.09

e9/l

250.04

13908

70970

All-cause Heart Failure

16372

90639

1.75

307.65

10.3

9.0

4.96

4.18

e9/l

215.28

14580

78101

Sleep apnoea

29729

165404

1.51

307.65

8.3

9.6

4.27

4.07

e9/l

41.35

26248

144761

Other anxiety disorders

16012

99530

2.13

307.65

10.7

8.3

4.11

3.99

e9/l

10.12

13873

87731

Myalgia

7169

49726

2.25

307.65

9.2

9.1

3.99

4.02

e9/l

0.78

6363

43324

Ulcerative colitis, NAS

5082

28323

5.16

307.65

16.1

8.9

3.98

4.05

e9/l

1.65

4757

24686

Diverticular disease of intestine

24976

114575

2.20

307.65

9.2

8.8

4.36

4.11

e9/l

45.33

21760

99397

Personality disorders, excluding more controls

8868

56386

2.65

307.65

13.6

7.7

4.22

3.93

e9/l

28.33

7727

49739

Substance abuse, excluding more controls

18064

117538

1.80

307.65

11.9

8.3

4.58

4.08

e9/l

126.64

15882

102974

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

35318

133652

2.63

307.65

15.3

6.9

3.85

4.16

e9/l

99.17

31471

115901

Other intervertebral disc disorders

29084

136490

1.69

307.65

8.3

9.2

4.12

4.11

e9/l

0.16

25907

118545

Other dorsopathies, not elsewhere classified

38792

152863

1.78

307.65

8.6

9.0

4.13

4.09

e9/l

2.37

34364

132801

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

15362

72307

5.02

307.65

25.5

6.5

4.02

4.28

e9/l

28.23

14367

61789

Fibromyalgia

2951

17092

4.37

307.65

8.7

9.0

3.95

3.90

e9/l

0.81

2700

14965

Etanercept

2441

11813

62.60

307.65

20.5

8.9

3.78

3.97

e9/l

5.89

2402

10351

Seropositive rheumatoid arthritis, wide

10296

57978

5.94

307.65

17.5

8.6

4.06

4.10

e9/l

1.14

9757

50147

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

9142

61769

2.25

307.65

14.0

7.6

4.30

3.95

e9/l

39.45

8105

54497

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

39391

181188

2.77

307.65

14.6

7.9

4.11

4.10

e9/l

0.22

35797

157083

Pain in joint

23913

96363

2.81

307.65

9.1

8.8

3.99

4.02

e9/l

1.41

21211

83390

Coagulation defects, purpura and other haemorrhagic conditions

5804

39020

2.59

307.65

17.2

8.8

3.92

4.12

e9/l

6.51

5279

34008

Biological medication for rheuma

6835

32119

64.31

307.65

21.2

9.0

3.81

3.98

e9/l

12.88

6741

28105

Other arthritis (FG)

11884

66781

4.38

307.65

12.9

8.3

4.13

4.07

e9/l

2.01

11003

57528

Paracetamol of NSAID medication

6682

21339

2.04

307.65

8.7

9.6

4.11

4.02

e9/l

1.79

5847

18271

Anaemias

10476

29262

6.10

307.65

15.7

4.9

3.97

3.87

e9/l

3.99

9566

25651

Reimbursement for rheumatic diseases

25524

138407

6.28

307.65

16.0

8.2

3.95

4.09

e9/l

22.19

24201

119696

Other/unspecified seropositive rheumatoid arthritis

10190

57303

5.99

307.65

17.6

8.6

4.06

4.10

e9/l

1.19

9656

49565

Disorders of the thyroid gland

32657

172012

1.55

307.65

9.3

8.8

4.01

4.14

e9/l

19.11

28843

150227

Non-follicular lymphoma, hilmo, excluding all cancers

2938

14994

6.19

307.65

26.3

6.3

3.53

4.33

e9/l

73.81

2745

12831

Other diseases of pleura

13009

84911

1.92

307.65

13.6

8.7

4.77

4.25

e9/l

80.44

11737

73231

Other diseases of urinary system

36648

162470

1.62

307.65

9.7

8.6

4.22

4.08

e9/l

19.63

32160

141996

Asthma, unspecified (mode)

20247

99075

2.75

307.65

9.5

7.6

4.41

3.90

e9/l

160.32

17944

85449

Autoimmune diseases excluding thyroid diseases, strict definition

45770

152508

3.06

307.65

13.3

7.6

4.07

4.14

e9/l

7.98

42075

131050

Diseases of arteries, arterioles and capillaries (FINNGEN)

7975

35778

2.48

307.65

10.6

9.1

4.72

3.80

e9/l

163.95

7015

30972

Falls/tendency to fall

39618

168106

1.37

307.65

9.0

4.18

4.05

e9/l

20.59

34531

147529

Chronic periodontitis

4532

28473

3.08

307.65

17.3

8.6

4.40

4.17

e9/l

8.17

4095

24758

Non-rheumatic valve diseases

14061

77654

1.77

307.65

9.5

9.4

4.33

4.06

e9/l

31.45

12360

67202

Other noninfective gastroenteritis and colitis

7793

51924

2.53

307.65

13.2

8.7

4.16

4.08

e9/l

2.16

7028

44927

Ulcerative rectosigmoiditis

2870

15786

5.61

307.65

15.0

8.8

3.90

4.07

e9/l

4.86

2682

13836

Venous thromboembolism

16385

120169

1.82

307.65

13.4

8.6

4.28

4.19

e9/l

5.14

14560

104262

Crohn's disease of small intestine

2532

12851

10.03

307.65

19.5

8.7

3.99

4.03

e9/l

0.43

2454

11261

Iron deficiency anaemia

13352

90062

2.40

307.65

11.7

8.6

4.34

4.17

e9/l

11.78

12008

77970

Other diseases of upper respiratory tract

39703

168912

1.49

307.65

8.7

9.1

4.07

4.13

e9/l

4.82

34787

147255

Implicit Sepsis

24959

138892

2.05

307.65

12.2

8.3

4.59

4.06

e9/l

156.89

22289

120211

Depression medications

12917

34809

2.96

307.65

10.2

4.9

4.08

3.89

e9/l

16.00

11426

30685

Sleep apnoea, including avohilmo

31810

169797

1.50

307.65

8.2

9.5

4.25

4.07

e9/l

36.90

28098

148690

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

5151

32293

2.68

307.65

15.7

6.1

4.02

4.42

e9/l

23.99

4529

27475

Crohn disease

4947

26210

6.90

307.65

17.9

8.9

3.99

4.04

e9/l

0.94

4721

22888

Asthma

32343

110459

2.48

307.65

9.1

7.6

4.33

3.91

e9/l

173.83

28835

95337

Condition for Implicit Sepsis (Organ dysfunction codes)

28767

158299

1.78

307.65

11.5

8.4

4.45

4.03

e9/l

121.08

25541

137474

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

2577

12962

12.38

307.65

19.7

8.9

3.94

4.00

e9/l

0.84

2481

11396

Certain infectious and parasitic diseases

40147

143583

1.94

307.65

11.9

7.1

4.20

3.98

e9/l

52.56

35615

124387

Benign neoplasms

35209

158549

1.51

307.65

9.3

8.8

4.14

4.11

e9/l

1.13

30983

138791

ILD, hospital admission 2, with pulmonary infections

2827

15827

4.17

307.65

17.9

7.6

4.97

4.12

e9/l

60.13

2651

13573

Malaise and fatigue

17311

93003

2.52

307.65

11.6

7.5

4.41

4.13

e9/l

37.39

15346

79796

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

6763

38377

4.86

307.65

15.1

9.1

3.88

4.06

e9/l

12.22

6302

33607

Pneumonia, organism unspecified

33494

171731

2.10

307.65

14.1

8.1

4.67

3.96

e9/l

307.65

30075

149216

Asthma (only as main-diagnosis)

28460

110459

2.42

307.65

8.8

7.6

4.32

3.91

e9/l

150.71

25525

95337

Hypothyroidism and >3 levothyroxin purchases

10392

32275

2.95

307.65

9.7

4.8

3.95

3.90

e9/l

1.39

9312

28405

Disorders of gallbladder, biliary tract and pancreas

33164

170338

1.59

307.65

10.4

8.8

4.41

4.07

e9/l

96.59

29428

148518

Non-allergic asthma (mode)

6229

39670

2.47

307.65

8.9

7.5

4.36

3.89

e9/l

49.84

5610

33984

Dialysis, with operation codes

4046

23800

4.34

307.65

21.7

9.0

4.68

4.12

e9/l

35.38

3799

20610

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

2446

12547

5.79

307.65

28.9

6.0

3.63

4.40

e9/l

53.24

2275

10711

General symptoms and signs

46175

155124

2.26

307.65

11.9

7.5

4.13

4.05

e9/l

9.09

41431

134181

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

33327

175908

1.68

307.65

11.9

8.6

4.18

4.07

e9/l

14.33

30004

152799

L04AD Calcineurin inhibitors

3989

20552

16.00

307.65

29.7

9.2

4.00

e9/l

0.07

3864

17913

Neoplasms

30271

112684

1.99

307.65

12.0

6.7

4.01

4.10

e9/l

8.17

26817

98155

Malignant neoplasm

35324

134845

2.63

307.65

15.7

6.9

3.83

4.17

e9/l

122.06

31733

116528

Malignant neoplasm of digestive organs

10645

76419

1.96

307.65

17.9

8.2

4.12

4.33

e9/l

13.50

9738

65795

Bacterial infection, other or unspecified

19284

104179

3.48

307.65

20.3

7.6

4.67

4.09

e9/l

143.10

17598

89632

Used for control exclusion in common control thyroid runs

44532

147915

2.35

307.65

11.5

7.6

4.03

4.14

e9/l

17.87

40235

127068

Cholelithiasis, broad definition with cholecystitis

27583

157053

1.45

307.65

9.2

8.7

4.40

4.07

e9/l

72.25

24387

136907

Hypertensive diseases

27975

120180

1.73

307.65

10.4

9.1

4.34

3.88

e9/l

174.18

24765

105350

Other nutritional deficiencies

20770

158629

1.70

307.65

9.5

8.9

4.56

4.00

e9/l

221.73

18319

139242

Crohn's disease of large intestine

1890

9547

10.17

307.65

20.0

8.8

4.00

4.01

e9/l

0.08

1818

8363

ILD, hospital admissions 1, main diag only

3924

23970

3.77

307.65

15.6

8.7

4.74

4.27

e9/l

27.86

3635

20737

Aplastic and other anaemias

14627

90433

2.67

307.65

15.3

8.3

4.24

4.27

e9/l

0.39

13241

77882

Selective serotonin reuptake inhibitors

37204

153030

1.61

307.65

10.1

8.5

4.16

4.09

e9/l

6.39

32447

133755

Acute bronchitis

12449

91491

1.79

307.65

12.9

8.6

4.51

4.15

e9/l

51.37

11196

79291

COPD/asthma related infections

40424

151012

1.80

307.65

11.5

7.7

4.32

3.94

e9/l

154.98

36079

130854

Psoriatic arthropathies, ICD10

3804

20523

8.70

307.65

15.7

9.3

3.88

4.05

e9/l

6.41

3637

17964

Crohn disease (strict definition, require KELA)

2432

12100

14.67

307.65

20.0

9.0

3.95

4.00

e9/l

0.74

2346

10658

Abnormal findings on examination of blood, without diagnosis

14156

95438

2.07

307.65

11.5

9.0

4.39

4.24

e9/l

9.26

12623

82937

Gout, idiopatic and unspecified

6810

45941

2.50

307.65

10.4

8.9

4.90

4.34

e9/l

55.10

5982

39798

Complications of medical and surgical care

24818

172781

1.99

307.65

11.7

8.7

4.31

4.10

e9/l

31.01

22168

150667

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

35322

133663

2.63

307.65

15.3

6.9

3.85

4.16

e9/l

99.12

31481

115908

Primary_lymphoid and hematopoietic malignant neoplasms

8212

47724

4.51

307.65

28.7

8.1

3.50

4.26

e9/l

121.81

7679

41203

Hypothyroidism, other/unspecified

29979

161902

1.50

307.65

9.2

8.7

4.02

4.13

e9/l

13.87

26594

141445

Anxiety disorders

32865

174121

1.85

307.65

11.1

8.7

4.09

4.03

e9/l

3.96

28833

152897

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

19822

146916

1.93

307.65

11.3

8.7

4.30

4.12

e9/l

20.69

17666

128019

Malignant neoplasm, wide definition for exclusion

35324

133676

2.63

307.65

15.3

6.9

3.85

4.16

e9/l

98.94

31483

115916

Symptoms and signs involving cognition, perception, emotional state and behaviour

33348

181994

1.67

307.65

9.7

9.0

4.17

4.10

e9/l

6.35

29250

159188

Benign neoplasms

27808

116313

1.76

307.65

9.3

6.9

4.11

4.13

e9/l

0.70

24492

101467

Undetermined asthma, excluding more controls

4175

23665

3.57

307.65

10.1

7.5

4.37

3.85

e9/l

35.71

3684

20297

Seropositive rheumatoid arthritis

10300

53009

6.97

307.65

17.5

8.2

4.06

4.09

e9/l

0.70

9760

45424

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

18228

137235

1.88

307.65

10.8

8.9

4.30

4.12

e9/l

17.19

16206

119717

Benign neoplasm: Colon

15330

75927

2.52

307.65

10.1

6.5

4.26

4.24

e9/l

0.59

13420

65076

Endocrine, nutritional and metabolic diseases

31710

121934

1.70

307.65

10.3

8.3

4.22

3.90

e9/l

93.95

27951

106708

Follow-up examination after treatment for conditions other than malignant neoplasms

15221

74309

1.74

307.65

8.8

8.0

4.04

4.12

e9/l

3.59

13315

63166

Enlarged lymph nodes

5724

31719

4.46

307.65

17.1

7.7

3.79

4.05

e9/l

12.91

5308

27320

Nutritional anaemias

15544

105887

2.20

307.65

11.6

8.6

4.31

4.18

e9/l

8.58

13954

91682

Finngen Rheumatological endpoints

40237

150969

2.39

307.65

10.9

8.2

4.07

4.09

e9/l

0.94

36460

130604

First line medication for Crohn's disease

53047

160253

3.81

307.65

14.9

6.3

4.15

4.05

e9/l

16.67

48857

136816

IBD patients in KELA-register

9360

50587

5.96

307.65

16.2

8.9

3.90

4.04

e9/l

10.10

8803

44268

Osteoporosis

7230

48288

2.30

307.65

12.8

8.5

4.41

4.15

e9/l

13.51

6537

41510

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

36625

185169

2.03

307.65

14.0

8.2

4.63

3.96

e9/l

307.65

32851

161140

Other and unspecified nonorganic psychotic disorders

6479

41600

2.77

307.65

26.9

7.9

4.36

3.97

e9/l

35.93

5770

36608

Lower back pain or/and sciatica

37432

195174

1.82

307.65

8.8

8.9

4.15

4.10

e9/l

3.41

33319

170363

Symptoms and signs involving the nervous and musculoskeletal systems

17673

139651

1.66

307.65

9.4

9.0

4.14

4.12

e9/l

0.58

16006

121484

Other anaemias

13571

84474

2.74

307.65

15.1

8.3

4.24

4.28

e9/l

0.83

12239

72736

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

4379

22437

6.05

307.65

24.7

6.3

3.57

4.34

e9/l

100.14

4094

19181

Neurotic, stress-related and somatoform disorders

32557

172745

1.86

307.65

11.2

8.7

4.08

4.03

e9/l

4.04

28561

151726

Schizophrenia, schizotypal and delusional disorders

10561

72881

2.28

307.65

26.1

8.2

4.39

4.03

e9/l

49.80

9474

63896

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

15682

73327

1.80

307.65

11.1

8.6

3.95

3.81

e9/l

11.37

14091

64241

Non-follicular lymphoma

2938

17039

4.92

307.65

26.3

8.7

3.53

4.25

e9/l

62.57

2745

14783

Urticaria and erythema

11381

85189

1.90

307.65

10.3

9.0

4.08

4.01

e9/l

2.75

10232

74435

Syncope and collapse

13678

88570

1.84

307.65

9.2

7.5

4.29

4.16

e9/l

8.45

12068

75909

ILD differential diagnosis

32122

111207

2.03

307.65

10.5

7.6

4.20

3.91

e9/l

74.09

28462

96015

Interstitial lung disease

4424

27267

3.46

307.65

15.5

8.6

4.74

4.29

e9/l

28.25

4105

23577

Opioids

40337

146269

2.09

307.65

10.5

7.9

4.25

4.01

e9/l

64.75

35724

127335

Persons encountering health services in other circumstances, wide

46581

179377

1.83

307.65

11.1

8.4

4.14

4.10

e9/l

2.29

41249

156215

Spondyloarthritis

6325

36370

3.63

307.65

13.3

8.2

3.98

4.15

e9/l

9.07

5951

31446

Other interstitial pulmonary diseases

4424

27253

3.46

307.65

15.5

8.6

4.74

4.29

e9/l

28.57

4105

23559

Undetermined asthma

4175

23995

3.49

307.65

10.1

7.5

4.37

3.88

e9/l

32.37

3684

20617

Systemic connective tissue disorders

12763

78001

3.76

307.65

13.3

8.6

4.25

4.09

e9/l

12.43

11862

67536

Glucagon-like peptide-1 (GLP-1) analogues

16073

104573

1.66

307.65

9.7

9.3

4.93

4.05

e9/l

307.65

14069

90724

Intestinal infectious diseases

32521

198756

1.63

307.65

11.8

8.5

4.30

4.07

e9/l

47.25

29079

173226

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

16001

123581

1.63

307.65

8.8

9.5

4.06

4.10

e9/l

1.33

14150

108199

Certain disorders involving the immune mechanism

6170

39663

3.16

307.65

15.0

9.3

4.03

4.07

e9/l

0.77

5725

34617

Obesity and other hyperalimentation

19515

153442

1.64

307.65

9.3

9.0

4.60

4.00

e9/l

243.28

17172

134719

Heart failure and antihypertensive medication

8279

33141

2.80

307.65

12.1

9.6

4.88

3.78

e9/l

215.72

7438

28750

Gingivitis and periodontal diseases

32166

133225

1.53

307.65

9.9

8.1

4.13

e9/l

0.06

27918

116205

Codeine or tramadol medication

44534

178758

1.97

307.65

9.3

8.8

4.27

4.07

e9/l

54.20

39324

156274

Other specific joint derangements/joint disorders

28507

127613

2.34

307.65

8.9

8.7

3.99

4.09

e9/l

11.97

25410

110713

DVT of lower extremities and pulmonary embolism

12198

89951

1.91

307.65

13.8

8.7

4.35

4.21

e9/l

7.43

10861

77852

Gout, FINNGEN

8261

54488

2.47

307.65

12.1

8.1

4.80

4.36

e9/l

38.01

7305

46753

Personality disorders

8868

61841

2.25

307.65

13.6

8.7

4.22

4.00

e9/l

17.88

7727

54521

Neurological diseases

33985

130777

1.67

307.65

9.1

9.0

4.11

4.03

e9/l

7.74

30059

113598

Osteopathies and chondropathies

17410

123976

1.88

307.65

12.1

8.8

4.28

4.09

e9/l

16.89

15580

107781

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

21950

137524

2.50

307.65

12.5

8.7

4.37

4.14

e9/l

33.86

19771

119224

Hypothyroidism, strict autoimmune

24925

125768

1.68

307.65

9.3

7.3

4.02

4.15

e9/l

13.35

22116

108046

Hypertensive diseases (excluding secondary)

19619

79305

2.06

307.65

10.8

8.7

4.33

3.81

e9/l

168.73

17459

69539

Second line medication for Crohn's disease

27144

134011

14.63

307.65

20.1

7.8

3.91

4.07

e9/l

34.62

26070

115993

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

35159

150788

2.23

307.65

14.0

7.7

4.60

3.94

e9/l

307.65

31526

130663

Psychiatric diseases

41077

159797

1.65

307.65

10.7

8.3

4.22

4.03

e9/l

43.82

36013

139796

Pneumonias (Asthma/COPD co-morbidities)

37812

186829

2.07

307.65

14.0

8.1

4.61

3.96

e9/l

307.65

33871

162619

Other systemic involvement of connective tissue

9615

59325

3.61

307.65

12.0

8.6

4.19

4.09

e9/l

4.27

8884

51400

Disorders of adult personality and behaviour

9300

65721

2.16

307.65

14.0

8.7

4.24

3.99

e9/l

20.49

8115

57967

Other diseases of the digestive system

9071

65519

1.98

307.65

11.6

8.6

4.53

4.27

e9/l

14.19

8129

56543

Dysphagia

7224

48806

2.34

307.65

9.9

8.5

4.17

4.13

e9/l

0.84

6427

41989

Cerebrovascular diseases (FINNGEN)

10315

51378

2.05

307.65

9.8

8.8

4.36

3.78

e9/l

99.49

9101

44767

Pain in limb

29401

146973

2.20

307.65

9.9

9.0

4.20

4.11

e9/l

8.36

25882

127792

Symptoms and signs involving the skin and subcutaneous tissue

22956

171920

1.88

307.65

10.5

8.9

4.00

4.11

e9/l

10.83

20598

150074

Care involving use of rehabilitation procedures

21891

149429

2.02

307.65

11.0

8.1

4.19

4.07

e9/l

11.58

19615

129377

Kela-code for severe mental illness

12283

86607

2.16

307.65

23.4

8.2

4.39

4.04

e9/l

52.03

11044

75862

Fall on same level

40294

188973

1.41

307.65

9.4

8.9

4.24

4.05

e9/l

37.08

35102

165760

Specific personality disorders

7601

52894

2.26

307.65

14.3

8.6

4.22

3.99

e9/l

16.40

6660

46662

Ulcerative colitis

9275

54023

4.15

307.65

14.8

8.9

3.98

4.07

e9/l

4.17

8630

47161

Spondylosis

16782

107461

1.84

307.65

8.6

9.3

4.17

4.12

e9/l

2.02

14944

93022

Other external causes of accidental injury

30711

127615

1.42

307.65

9.1

8.9

4.15

4.04

e9/l

12.79

26673

112164

Other arrhythmias

20787

124273

1.65

307.65

8.4

9.1

4.05

3.99

e9/l

2.75

18284

108509

Ankylosing spondylitis

3195

17152

5.39

307.65

14.0

9.5

3.92

4.09

e9/l

4.99

3020

14937

Hypertension

27952

120083

1.73

307.65

10.4

9.1

4.34

3.88

e9/l

174.50

24741

105274

Mental and behavioural disorders due to psychoactive substance use

18627

137895

1.63

307.65

11.8

9.0

4.58

4.11

e9/l

115.46

16393

120688

Pulmonary heart disease

8281

59565

2.06

307.65

14.7

8.6

4.42

4.22

e9/l

8.63

7397

51536

Unspecified mental disorder

13730

97817

2.10

307.65

21.7

8.1

4.35

4.04

e9/l

47.50

12250

85795

Early onset COPD, excluding more controls

6017

38777

2.43

307.65

12.0

7.8

5.02

3.96

e9/l

173.55

5417

33246

Mood disorders, excluding more controls

35652

158461

1.91

307.65

10.5

8.2

4.17

4.03

e9/l

19.99

31119

138874

Diseases of the digestive system

13872

102350

1.90

307.65

11.4

8.8

4.35

4.20

e9/l

8.27

12463

88675

Diseases of the eye and adnexa

31244

123402

1.56

307.65

9.6

8.8

4.05

4.04

e9/l

0.25

27655

107670

In situ neoplasms

9946

67290

2.02

307.65

10.1

6.3

4.07

4.24

e9/l

11.44

8737

57711

Benign neoplasm of colon, rectum, anus and anal canal

17864

82663

2.48

307.65

10.0

6.5

4.23

4.21

e9/l

0.53

15614

71026

Benign neoplasm: Colon, unspecified

6354

42473

2.30

307.65

9.9

6.2

4.36

4.35

e9/l

0.17

5497

36206

GASTRO-related operations

35523

110689

2.47

307.65

11.3

6.5

4.21

3.92

e9/l

75.88

31563

95326

Persons encountering health services for examination and investigation

25306

92890

1.75

307.65

9.6

8.0

4.09

4.16

e9/l

3.95

22539

78962

Persons encountering health services for specific procedures and health care

42926

182630

2.23

307.65

13.1

8.0

4.18

4.06

e9/l

18.17

38566

158547

Sciatica+with lumbago

16758

115933

1.96

307.65

8.5

9.3

4.15

4.07

e9/l

4.73

14983

100797

General examination and investigation of persons without complaint and reported diagnosis

24870

92752

1.94

307.65

10.9

8.0

4.08

4.16

e9/l

4.72

22942

78868

Other disorders of lacrimal gland

10446

75599

2.15

307.65

11.2

9.0

3.97

4.07

e9/l

5.04

9478

65883

Persons encountering health services in other circumstances

11951

88901

1.85

307.65

12.3

8.2

4.23

4.08

e9/l

10.08

10910

77440

Medical observation and evaluation for suspected diseases and conditions

27454

92873

2.20

307.65

10.3

8.0

4.10

4.16

e9/l

2.92

24779

78951

Other special examinations and investigations of persons without complaint or reported diagnosis

26353

92887

1.95

307.65

9.9

8.0

4.08

4.16

e9/l

5.71

23870

78961

Persons encountering health services for other counselling and medical advice, not elsewhere classified

42417

178343

1.89

307.65

10.7

8.4

4.06

4.09

e9/l

1.89

37427

155414

Other medical care

14710

86019

3.61

307.65

19.8

7.8

4.30

4.17

e9/l

6.69

13647

73807

Examination and observation for other reasons

24397

92015

2.65

307.65

11.0

8.1

4.08

4.15

e9/l

3.69

21835

78266

Disorders of lacrimal system

12724

95780

1.91

307.65

10.7

9.0

3.98

4.08

e9/l

6.71

11460

83427

Factors influencing health status and contact with health services

12061

39927

2.00

307.65

9.7

6.9

4.13

4.14

e9/l

0.10

10650

33603

Care involving dialysis

2500

13682

5.48

307.65

18.4

8.4

4.77

4.13

e9/l

28.58

2368

11794

Exposure to unspecified factor

33187

205615

1.59

307.65

9.7

8.9

4.22

4.08

e9/l

18.62

28443

180522

Any gastric operation

35523

110689

2.47

307.65

11.3

6.5

4.21

3.92

e9/l

75.88

31563

95326

Vocal cord dysfunction

4374

24078

2.77

307.65

9.7

7.5

4.16

3.76

e9/l

24.49

3893

20645

Codes for special purposes

15301

106116

2.33

307.65

12.6

8.6

4.27

4.09

e9/l

16.86

13539

92889

Provisional assignment of new diseases of uncertain etiology

15283

106002

2.33

307.65

12.6

8.6

4.27

4.09

e9/l

16.77

13523

92796

Transplanted organ and tissue status

3329

17999

7.16

307.65

33.4

9.1

3.95

4.02

e9/l

1.08

3172

15555

Disorders of thyroid, IBD co-morbidities

7160

26281

3.79

307.65

9.4

8.0

3.89

3.91

e9/l

0.32

6291

22506

Hypothyreosis and Thyroxine purchase for inclusion criteria

30861

168171

1.48

307.65

9.2

8.7

4.01

4.13

e9/l

13.74

27361

146868

Poisoning by medicine

6872

47762

2.27

307.65

14.2

8.8

4.43

3.98

e9/l

44.63

6085

42004

Intracranial trauma

19337

112717

1.60

307.65

8.9

9.1

4.21

3.99

e9/l

30.13

17060

97965

Poisoning by drugs, medicaments and biological substances

7634

53317

2.23

307.65

14.4

8.8

4.41

3.99

e9/l

46.53

6760

46877

Asthma and allergy, excluding more controls

4418

26944

2.64

307.65

7.7

7.5

4.06

3.80

e9/l

13.29

3925

23369

Asthma, unspecified (mode), excluding more controls

19893

94649

2.87

307.65

9.6

7.6

4.40

3.87

e9/l

173.22

17646

81668

Allergic asthma (mode), excluding more controls

8198

52612

2.29

307.65

7.9

7.5

4.18

3.85

e9/l

32.13

7293

45587

Complications of surgical and medical care, not elsewhere classified

35934

185825

2.03

307.65

11.2

8.6

4.27

4.09

e9/l

32.64

32158

161909

Complications of procedures, not elsewhere classified

28296

178362

1.99

307.65

10.6

8.6

4.29

4.09

e9/l

30.77

25317

155418

Injuries to the head

36659

202057

1.39

307.65

9.0

4.23

4.08

e9/l

28.45

32110

176725

Covid-19 confirmed case

9631

61042

3.16

307.65

14.6

8.6

4.39

4.14

e9/l

18.55

8421

53237

Dentinal caries

7907

47980

3.23

307.65

19.7

8.3

4.28

4.10

e9/l

8.61

7241

41775

Codeine

38254

143561

2.17

307.65

9.3

7.9

4.27

4.02

e9/l

73.18

33777

125050

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

10100

56395

6.49

307.65

17.6

8.6

4.05

4.09

e9/l

1.11

9577

48796

Symptoms and signs involving the circulatory and respiratory systems

40893

146441

1.93

307.65

9.5

8.7

4.14

4.05

e9/l

10.69

36343

127189

Symptoms and signs involving the digestive system and abdomen

40380

144772

1.92

307.65

10.0

8.6

4.21

4.04

e9/l

35.00

35766

125564

Symptoms and signs involving the urinary system

24563

148213

1.67

307.65

10.6

9.0

4.33

4.12

e9/l

28.48

21534

129090

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

15686

46427

2.43

307.65

9.6

7.0

4.07

3.88

e9/l

16.89

13843

39889

Pain in throat and chest

32506

137961

2.07

307.65

9.4

8.8

4.13

4.05

e9/l

7.07

28698

119850

Pain, not elsewhere classified

9207

58185

2.78

307.65

11.4

7.6

4.18

4.05

e9/l

6.34

8311

50167

Abnormalities of heart beat

11052

77716

2.01

307.65

9.4

8.6

4.08

e9/l

0.15

9835

67153

Haemorrhage from respiratory passages

10775

66855

2.28

307.65

10.6

8.9

4.38

4.20

e9/l

10.38

9544

57381

Fever of other and unknown origin

21813

119537

3.29

307.65

18.6

7.5

4.23

4.09

e9/l

11.31

20130

102997

Abnormalities of breathing

36145

145695

2.19

307.65

9.8

8.7

4.24

4.05

e9/l

41.93

32468

126541

Other acute lower respiratory infections

16779

122396

1.72

307.65

12.6

8.6

4.49

4.13

e9/l

65.15

15046

106322

Oedema, not elsewhere classified

10184

64182

2.77

307.65

11.9

7.5

4.39

4.12

e9/l

23.75

9150

54967

Visual disturbances and blindness

15234

119276

1.70

307.65

9.9

8.9

4.11

4.12

e9/l

0.34

13398

103966

Disturbances of skin sensation

8439

60596

2.12

307.65

9.2

8.9

3.94

4.04

e9/l

4.19

7516

53074

Hypothyroidism (congenital or acquired)

10483

32454

2.96

307.65

9.8

4.8

3.95

3.89

e9/l

1.73

9390

28556

Dyspnoea

32696

175192

2.20

307.65

10.3

8.8

4.35

4.08

e9/l

71.94

29473

152211

Nausea and vomiting

8664

54966

2.55

307.65

14.4

8.4

4.36

4.06

e9/l

22.77

7864

47191

Abnormal findings on diagnostic imaging of lung

15684

100187

2.72

307.65

13.0

8.8

4.47

4.20

e9/l

30.19

14177

86570

Other heart diseases, wide

33218

157731

1.72

307.65

10.0

9.1

4.18

3.98

e9/l

41.91

29330

138094

Cough

14124

91502

2.35

307.65

9.9

8.9

4.02

4.04

e9/l

0.37

12684

79096

Dizziness and giddiness

24360

154108

1.68

307.65

9.1

9.0

4.16

4.12

e9/l

1.91

21444

134537

Headache

24237

138958

2.18

307.65

9.1

7.5

4.04

4.02

e9/l

0.69

21718

120416

Abdominal and pelvic pain

40223

144739

1.92

307.65

9.5

8.6

4.24

4.04

e9/l

43.00

35610

125547

Schizophrenia

5419

33709

3.19

307.65

39.6

8.3

4.47

4.02

e9/l

45.00

5013

29565

Asthma, including avohilmo

44782

193094

1.85

307.65

8.5

9.1

4.30

4.05

e9/l

78.36

39674

168402

Obesity related asthma

10762

72988

2.54

307.65

9.3

4.57

4.02

e9/l

110.54

9691

63626

Other/unspecified rheumatoid arthritis

3942

24192

3.66

307.65

16.6

8.6

4.27

4.13

e9/l

3.49

3702

20980

Cardiovascular diseases

23875

93358

1.89

307.65

10.4

8.2

4.07

3.86

e9/l

34.96

21239

81808

Other pulmonary diagnosis

32296

111534

2.04

307.65

10.5

7.6

4.21

3.91

e9/l

81.20

28594

96280

Other disorders of teeth and supporting structures

6457

44070

2.34

307.65

14.1

8.4

4.30

4.13

e9/l

6.97

5963

38412

Other psoriatic arthropathies

3710

19922

8.97

307.65

15.7

9.2

3.88

4.04

e9/l

5.98

3549

17438

Psoriatic and enteropathic arthropathies

4542

22493

9.17

307.65

16.2

8.7

3.92

4.04

e9/l

4.00

4350

19425

Anxiety (asthma-related co-morbidities)

21791

120900

2.09

307.65

10.7

8.0

4.11

3.95

e9/l

20.38

18926

106633

Concussion

16377

109107

1.64

307.65

8.7

9.2

4.18

3.99

e9/l

20.62

14515

94763

Hypothyroidism, levothyroxine purchases

10392

32275

2.95

307.65

9.7

4.8

3.95

3.90

e9/l

1.39

9312

28405

Oxycodone

12776

70893

3.82

307.65

21.3

7.9

4.48

4.14

e9/l

33.04

11904

61020

Autoimmune diseases related-to ILD

36934

191122

3.66

307.65

13.6

8.1

4.02

4.11

e9/l

13.43

34247

165327

Medicines for HER+ breast cancer

12094

76477

3.27

307.65

13.1

8.7

3.47

4.01

e9/l

157.48

11198

66184

Pulmonary heart disease, diseases of pulmonary circulation

9028

65187

2.03

307.65

14.5

8.6

4.44

4.23

e9/l

10.70

8078

56375

Adalimumab

3658

17240

65.25

307.65

21.3

8.9

3.87

3.97

e9/l

3.11

3614

15127

ILD medications: immunosuppressive drugs

32120

138885

16.83

307.65

20.5

7.0

3.93

4.01

e9/l

11.97

30875

118796

Budesonide

5035

25521

6.65

307.65

17.6

7.6

3.96

3.98

e9/l

0.40

4714

21883

L04AX Other immunosuppressants

26309

130383

14.46

307.65

20.1

7.9

3.92

4.07

e9/l

31.31

25279

112894

Diseases of the respiratory system

25037

91910

1.79

307.65

10.0

7.8

4.17

3.91

e9/l

47.07

22061

79195

Coxibs

10332

35397

2.20

307.65

8.2

10.3

4.22

4.25

e9/l

0.63

9075

30823

Dental operations

22885

92102

1.58

307.65

9.6

8.2

4.15

4.21

e9/l

2.75

20070

79319

Heart failure, not strict

25356

124755

2.13

307.65

11.9

9.1

4.72

4.00

e9/l

292.24

22764

107963

L04AA Selective immunosuppressants

8907

45984

14.21

307.65

23.3

8.8

4.02

4.01

e9/l

0.11

8665

40016

L02BA Anti-estrogens

5153

34008

3.08

307.65

15.7

8.8

3.38

3.96

e9/l

70.49

4798

29622

Papulosquamous disorders

13066

89311

2.51

307.65

12.5

9.0

4.07

4.09

e9/l

0.62

11965

77828

Tumor necrosis factor alpha inhibitors

6132

28865

63.68

307.65

20.9

9.0

3.79

3.97

e9/l

14.40

6046

25290

Azathioprine

6411

29316

15.11

307.65

23.4

7.7

3.96

e9/l

0.04

6263

25167

Sulfasalazine

12517

62239

7.79

307.65

15.7

7.6

3.90

4.00

e9/l

7.14

11839

53286

Parasetamol

33642

112065

2.24

307.65

10.0

8.1

4.24

3.95

e9/l

76.54

29895

96718

Methotrexate

5858

29004

8.88

307.65

18.9

7.5

4.02

3.96

e9/l

1.18

5645

24703

Dental pulpitis 2

24805

101541

1.53

307.65

9.4

8.2

4.17

4.13

e9/l

1.43

21606

88346

L02BG Aromatase inhibitors

9423

61118

3.44

307.65

13.7

8.9

3.47

4.00

e9/l

137.31

8744

52792

L04AC Interleukin inhibitors

1880

8865

65.97

307.65

23.3

9.1

4.00

e9/l

0.01

1854

7793

Oxicams

8088

29960

2.16

307.65

8.5

10.4

4.16

4.32

e9/l

6.89

7176

26069

Oral corticosteroids

48114

166842

3.62

307.65

13.3

7.4

4.34

4.05

e9/l

117.71

44571

142967

Acetic acid derivatives and related substances

9700

34957

1.89

307.65

8.2

10.3

4.24

4.26

e9/l

0.29

8386

30450

Ulcerative colitis (strict definition, all Crohn cases excluded)

5230

29396

4.88

307.65

14.3

9.0

3.87

4.07

e9/l

11.61

4842

25691

Dental caries 1, only avohilmo

27608

116339

1.45

307.65

9.1

8.7

4.15

4.13

e9/l

0.56

24084

101474

Acute sinusitis

17011

122427

1.70

307.65

10.7

8.5

4.16

4.02

e9/l

13.16

15237

107013

Genitourinary diseases

22483

85601

1.65

307.65

10.0

8.9

4.17

4.04

e9/l

11.69

19804

74598

Crohn disease (strict definition, all UC cases excluded)

1845

9247

12.03

307.65

18.9

8.8

3.92

4.03

e9/l

1.94

1780

8108

Chronic periapical parodontitis

6698

42681

2.91

307.65

17.7

8.5

4.22

4.12

e9/l

2.88

6172

37178

Other antidepressants

40190

152269

1.90

307.65

9.7

8.5

4.21

4.09

e9/l

17.74

35419

133128

Asthma (diagnoses ohter than nonallergic)

32225

196381

2.09

307.65

9.1

8.9

4.36

4.06

e9/l

99.66

28681

171328

Valvular heart disease excluding rheumatic fever

14159

78262

1.77

307.65

9.5

9.4

4.33

4.06

e9/l

32.87

12450

67729

Neurological diseases, wide definition

12808

38200

2.46

307.65

9.1

8.0

4.09

3.89

e9/l

16.18

11384

32720

Dental operations, only avohilmo

23884

99023

1.50

307.65

9.1

8.7

4.15

4.21

e9/l

2.77

20889

85818

5-aminosalicylic acid

8497

43970

5.57

307.65

15.2

7.7

3.92

4.00

e9/l

3.05

7936

37818

Inflammatory bowel disease treatment related agents

54104

173423

3.81

307.65

13.6

7.4

4.23

4.04

e9/l

56.14

50099

148594

Nephropathy related operations

3878

22975

4.44

307.65

22.1

9.3

4.68

4.16

e9/l

30.29

3645

19965

ILD medications

54702

164966

3.99

307.65

14.4

6.8

4.17

4.05

e9/l

23.86

50576

140906

Diseases of the musculoskeletal system and connective tissue

22009

76658

1.91

307.65

9.2

8.7

4.06

4.07

e9/l

0.23

19516

65827

ILD medications: azathioprine

6411

28598

15.76

307.65

23.4

7.0

3.96

3.97

e9/l

0.20

6263

24469

Dental caries 1 and operation codes

30291

127286

1.47

307.65

9.7

8.4

4.13

4.14

e9/l

0.58

26547

110743

Infections, IBD-co-morbidities

5911

21454

3.82

307.65

17.6

8.7

4.35

3.92

e9/l

25.59

5386

18278

Viral hepatitis, IBD co-morbidity

1964

8367

6.14

307.65

16.2

9.1

3.94

3.92

e9/l

0.14

1772

7194

Rheumatoid arthritis, including avohilmo

15070

85943

5.25

307.65

16.1

8.4

4.04

4.11

e9/l

4.23

14159

74359

Other disorders of fluid, electrolyte and acid-base balance

8986

59006

2.33

307.65

12.9

8.7

4.76

4.14

e9/l

79.18

8051

51164

Dental caries

8992

54990

3.08

307.65

20.1

8.3

4.25

4.09

e9/l

8.23

8213

47854

ILD, hospital admissions

4405

26882

3.64

307.65

15.5

8.6

4.74

4.29

e9/l

28.03

4086

23246

Dental caries 3 and operation codes

31679

134036

1.46

307.65

9.6

8.4

4.12

4.13

e9/l

0.07

27798

116572

ILD medications: prednisolone, methylprednisolone, prednisone

50280

161606

3.54

307.65

13.7

6.8

4.27

4.06

e9/l

67.58

46259

138039

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

4155

13025

6.57

307.65

16.1

9.1

4.71

3.99

e9/l

52.79

3866

11027

Dental caries, including avohilmo

27286

113296

1.49

307.65

9.5

8.3

4.15

4.13

e9/l

0.80

23810

98670

Gastrointestinal diseases

24835

84129

2.05

307.65

10.2

7.2

4.11

3.92

e9/l

28.05

22021

72549

Diseases of pulp and periapical tissues, including avohilmo

38341

166615

1.42

307.65

9.9

8.5

4.19

4.07

e9/l

18.65

33516

145556

Dental caries 1

27313

113384

1.49

307.65

9.5

8.3

4.15

4.13

e9/l

0.85

23832

98756

All influenza

7637

52027

2.28

307.65

14.0

8.0

4.44

4.01

e9/l

39.05

6938

44930

Diseases of oral cavity, salivary glands and jaws

33158

134395

1.57

307.65

10.3

8.1

4.11

4.13

e9/l

0.84

29026

117084

Ankylosing spondylitis, ICD10

3079

17420

5.40

307.65

14.2

9.3

3.90

4.08

e9/l

6.51

2909

15264

Other specified/unspecified arthritis

10426

57093

4.82

307.65

13.0

8.8

4.13

4.10

e9/l

0.79

9662

49312

Constipation

29870

161750

1.81

307.65

11.6

8.8

4.15

4.11

e9/l

2.25

26250

141009

Acute renal failure

5938

38307

2.76

307.65

16.0

8.5

5.11

4.24

e9/l

90.29

5396

33003

Diseases of the skin and subcutaneous tissue

40493

148076

1.85

307.65

10.2

8.2

4.13

4.08

e9/l

3.73

36014

128186

Other and unspecified dermatitis

17206

121192

2.22

307.65

11.4

8.9

4.12

4.09

e9/l

0.79

15653

105491

Dental pulpitis 4, only avohilmo

38479

171218

1.37

307.65

9.4

8.7

4.19

4.07

e9/l

16.19

33562

149784

Arthropathic psoriasis

4076

21992

7.95

307.65

15.7

9.1

3.91

4.05

e9/l

4.79

3864

19192

Substance abuse

18064

134982

1.64

307.65

11.9

9.0

4.58

4.11

e9/l

113.06

15882

118129

Tramadol

30417

128609

2.38

307.65

10.8

8.0

4.34

4.02

e9/l

86.07

26814

111802

Ulcerative colitis (strict definition, require KELA)

6326

35199

5.35

307.65

15.3

9.1

3.89

4.06

e9/l

10.14

5908

30822

Schizophrenia or delusion

10542

72537

2.30

307.65

26.2

8.2

4.40

4.03

e9/l

51.10

9458

63609

Low back pain

26976

146332

2.08

307.65

9.1

9.0

4.17

4.10

e9/l

5.18

24009

127170

Dental pulpitis 4

38400

166820

1.42

307.65

9.9

8.5

4.19

4.07

e9/l

18.09

33556

145737

Mood disorders

38120

187929

1.82

307.65

10.5

8.7

4.16

4.06

e9/l

11.88

33258

164871

Gonarthrosis [arthrosis of knee](FG)

24688

112419

1.63

307.65

8.5

4.16

4.11

e9/l

2.35

21727

96904

Other diseases of hard tissues of teeth

21246

125070

1.61

307.65

10.9

8.3

3.91

4.07

e9/l

20.74

18769

109358

Diseases of pulp and periapical tissues

11552

79468

2.26

307.65

15.2

8.4

4.24

4.10

e9/l

8.04

10423

69460

Dental pulpitis 1

38395

166859

1.42

307.65

9.9

8.5

4.19

4.07

e9/l

18.29

33550

145776

Dental pulpitis 2, only avohilmo

25201

103716

1.51

307.65

9.3

8.3

4.17

4.13

e9/l

1.82

21950

90331

Other or unspecified ileus, impaction or obstruction

5286

34579

2.46

307.65

16.4

8.5

4.54

4.24

e9/l

10.94

4786

29826

GI-bleeding

9052

65581

1.95

307.65

11.6

8.6

4.55

4.28

e9/l

15.91

8131

56596

Inflammatory bowel disease

12315

71942

4.17

307.65

15.0

8.9

3.98

4.07

e9/l

5.64

11486

62819

Intestinal stricture

8931

63051

2.19

307.65

15.6

8.8

4.45

4.20

e9/l

14.40

8112

54595

Colectomy operation

4876

32443

2.73

307.40

15.6

8.8

4.24

4.21

e9/l

0.29

4321

28129

Disorders of other endocrine glands

13227

101312

1.71

307.10

10.8

8.8

4.26

4.08

e9/l

11.58

11858

88074

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

9142

67489

1.92

307.00

14.0

8.5

4.30

4.00

e9/l

30.49

8105

59429

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

9965

75204

1.90

304.37

9.5

9.2

3.97

4.03

e9/l

1.63

8735

65683

Ankylosing spondylitis, strict definition

1623

8016

13.11

301.79

15.0

9.5

3.78

4.05

e9/l

8.50

1568

7036

Kidney transplant status

1775

9216

12.60

299.79

20.9

9.7

4.37

4.03

e9/l

7.21

1693

8046

Viral infections characterized by skin and mucous membrane lesions

12406

96054

1.72

299.27

13.1

8.9

4.10

e9/l

0.03

11200

83744

Chronic gastritis

8027

58253

2.00

298.98

10.5

8.8

4.18

4.22

e9/l

0.62

6957

50167

Iridocyclitis

6790

48195

2.19

298.70

11.9

9.1

4.06

4.09

e9/l

0.56

6247

42004

Secondary and unspecified malignant neoplasm of lymph nodes

2597

15015

4.89

297.88

23.7

8.7

3.57

4.20

e9/l

44.51

2439

13011

Gout, strict definition

4791

31837

2.64

296.43

10.4

8.8

5.01

4.36

e9/l

46.98

4220

27605

Bacterial pneumoniae

12025

81518

1.70

295.99

14.3

7.9

4.83

4.05

e9/l

160.54

10735

70353

Alcohol use disorder, Swedish definition

16517

122459

1.57

295.66

11.4

9.1

4.59

4.14

e9/l

88.23

14443

107141

Ulcer of lower limb, not elsewhere classified

3923

24950

3.00

295.12

13.3

8.6

5.21

4.29

e9/l

69.51

3486

21521

Hernia

30078

172398

1.39

294.43

9.4

9.2

4.22

4.08

e9/l

17.91

26487

150614

Obesity due to excess calories

13966

110401

1.66

292.61

9.1

9.0

4.61

3.99

e9/l

186.91

12385

96848

Presence of cardiac and vascular implants and grafts

12700

74268

1.69

291.17

8.3

8.8

4.57

4.29

e9/l

26.51

11251

63621

Convulsions, not elsewhere classified

7104

49363

1.99

290.95

13.0

7.5

4.24

4.07

e9/l

6.82

6167

42578

Polymyalgia rheumatica

3735

23622

3.12

290.75

11.2

8.4

4.91

4.25

e9/l

48.55

3375

20276

Behavioural syndromes associated with physiological disturbances and physical factors

9828

73970

1.84

290.70

10.3

8.6

4.04

4.03

e9/l

0.08

8617

64945

Lung cancer and mesothelioma

5327

30231

2.27

290.50

15.1

7.3

4.97

4.05

e9/l

89.89

4747

25694

External causes of morbidity and mortality

24933

102847

1.43

289.80

9.4

8.5

4.13

4.00

e9/l

13.16

21853

89947

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

4994

32855

2.48

289.20

16.1

6.5

3.88

4.12

e9/l

9.98

4395

27953

Functional dyspepsia

7979

58398

1.99

288.06

9.3

8.9

4.00

4.05

e9/l

1.17

7154

50684

Secondary uncertain malignant neoplasm

3683

23218

3.07

287.04

21.8

8.5

3.91

4.26

e9/l

14.63

3457

20082

6-mercaptopurine

1163

4987

24.78

286.46

26.7

7.5

3.62

3.92

e9/l

7.67

1118

4272

Non-ischemic cardiomyopathy

8352

50354

1.95

284.97

11.1

9.1

4.89

4.13

e9/l

99.86

7376

43295

Nonorganic sleeping disorders, excluding more controls

5458

37024

2.27

284.49

9.8

7.9

4.11

3.97

e9/l

4.58

4772

32557

Golimumab

1264

5860

83.40

284.36

20.9

8.8

3.85

3.98

e9/l

1.69

1258

5146

Vasomotor and allergic rhinitis

12054

91888

1.69

284.01

7.8

9.2

3.91

3.99

e9/l

4.10

10718

80474

Sequelae of external causes of morbidity and mortality

7213

52304

2.10

283.41

12.0

9.0

4.38

4.14

e9/l

12.85

6477

45484

COPD

12461

79733

1.68

282.71

10.5

9.1

5.13

4.16

e9/l

265.42

11057

68655

Symptoms and signs concerning food and fluid intake

3119

18709

3.28

282.18

11.7

7.4

4.17

4.06

e9/l

1.68

2817

15991

Conjunctivitis

23815

173394

1.45

282.05

9.0

3.96

4.03

e9/l

4.80

20842

152078

Myeloproliferative diseases (CML excluded)

2370

13641

5.30

280.70

21.4

8.7

5.40

4.19

e9/l

23.94

2213

11838

Parodontitis and operation codes

26407

173247

1.42

280.28

10.5

9.1

4.23

4.09

e9/l

17.66

23042

151803

Bacterial pneumonia, not elsewhere classified

11335

76755

1.71

280.22

14.5

7.8

4.83

4.05

e9/l

155.60

10130

66207

Thyrotoxicosis, other and/or unspecified

5993

42143

2.27

279.68

9.6

8.9

3.87

4.04

e9/l

7.66

5209

36763

Disorders of skin appendages

14559

115951

1.61

279.31

10.7

8.9

4.12

4.04

e9/l

3.70

13069

101541

Non-selective monoamine reuptake inhibitors

11667

87417

1.70

279.25

10.9

8.9

4.27

4.05

e9/l

18.64

10351

76129

Diseases of the ear and mastoid process

40747

178409

1.32

278.85

8.9

9.0

4.08

4.09

e9/l

0.22

35917

155889

Sacroiliitis, not elsewhere classified

1723

8776

6.79

275.93

11.8

8.9

3.75

3.95

e9/l

5.25

1647

7712

Hypo-osmolality and hyponatraemia

4793

31982

2.45

275.71

12.7

8.6

4.74

4.17

e9/l

36.85

4297

27650

Adjustment and management of implanted device

5015

33687

2.34

275.50

9.1

7.6

4.43

4.34

e9/l

1.70

4147

28629

Colorectal cancer

6354

45090

2.15

274.52

16.6

8.6

3.98

4.31

e9/l

23.12

5779

38966

Purpura and other haemorrhagic conditions

3966

25878

2.88

272.37

20.3

8.7

3.84

4.14

e9/l

11.14

3658

22494

Mycoses

7601

55905

2.01

272.16

13.9

9.0

4.30

4.11

e9/l

9.55

6910

48639

Meniscus derangement

17177

94401

1.52

271.89

8.4

9.1

4.03

4.15

e9/l

8.31

15102

81681

Glomerular diseases

5218

35951

2.39

271.07

14.4

9.1

4.70

4.16

e9/l

43.96

4778

31232

Hypothyroidism, strict autoimmune, 3 medication purchases required

27281

157365

1.40

270.05

9.2

8.7

4.02

4.11

e9/l

9.33

24164

137439

4102

26765

2.68

269.95

15.2

8.4

4.11

4.01

e9/l

2.01

3626

23414

Cholecystectomy

21336

156757

1.47

269.93

9.3

8.9

4.38

4.09

e9/l

43.48

18851

136841

Hyperlipidaemia, other/unspecified

10796

78623

1.74

269.77

9.3

8.9

4.48

4.17

e9/l

30.92

9445

68276

Sarcoidosis

4042

26683

2.89

269.73

12.0

9.2

3.92

4.08

e9/l

4.87

3719

23293

18282

133504

1.50

269.06

11.1

9.0

4.57

4.12

e9/l

94.29

16011

116785

17330

129090

1.51

268.20

11.0

9.1

4.57

4.13

e9/l

89.12

15175

112906

Sicca syndrome [Sjögren]

2732

16655

4.29

266.56

12.4

8.9

3.65

3.97

e9/l

12.02

2557

14496

Thyrotoxicosis

7425

54713

2.03

266.28

9.5

8.9

3.91

4.03

e9/l

4.97

6476

47753

Other specified/unspecified inflammatory spondylopathies

1712

8845

6.67

266.12

13.2

9.2

3.89

3.97

e9/l

0.96

1631

7776

Heart failure and bmi 25plus

9349

48362

1.82

265.01

10.2

9.0

5.00

4.27

e9/l

114.95

8357

42258

Urticaria

9057

68539

1.85

264.83

9.7

8.9

4.08

4.00

e9/l

2.61

8108

59891

Other juvenile arthritis

1511

7443

7.97

264.82

18.2

8.5

3.90

3.86

e9/l

0.41

1457

6423

Other bacterial intestinal infections

5169

35427

2.29

263.59

15.5

8.4

4.55

4.15

e9/l

18.51

4669

30672

Disorders of synovium and tendon

16446

119761

1.53

263.50

8.7

9.2

4.04

4.07

e9/l

0.88

14736

104354

Disorders of lens

20398

106089

1.47

262.01

10.7

9.3

4.33

4.06

e9/l

40.97

18020

92056

Dentofacial anomalies [including malocclusion]

8523

62869

1.84

261.75

11.2

8.1

3.81

3.95

e9/l

7.89

7752

55084

Juvenile arthritis (FINNGEN)

1689

8694

6.35

261.66

18.1

8.0

3.91

e9/l

0.04

1625

7496

Other symptoms and signs involving cognitive functions and awareness

12451

91668

1.64

261.08

9.5

9.0

4.36

4.21

e9/l

7.73

10744

79604

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

13147

70429

1.60

260.78

9.5

6.4

4.16

4.28

e9/l

6.14

11431

60008

Special screening examination for infectious and parasitic diseases

8212

44431

1.78

260.75

8.6

7.8

3.84

4.05

e9/l

15.14

6797

38433

Emotionally unstable personality disorder

3931

25627

2.71

260.71

14.5

8.1

4.27

3.97

e9/l

14.86

3420

22639

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

5140

35458

2.33

260.53

14.6

8.9

4.42

3.97

e9/l

34.47

4543

31261

Other ulcerative colitis

1932

10566

5.73

259.91

17.2

8.8

3.97

4.07

e9/l

1.60

1838

9264

Benign neoplasm: Rectum, anus and anal canal

5051

34321

2.25

259.68

9.8

6.3

4.22

4.32

e9/l

2.36

4386

29316

Other necrotizing vasculopathies (FG)

1862

9980

5.46

257.67

18.1

8.3

4.97

4.13

e9/l

34.53

1753

8550

MS-disease / Multiple Sclerosis

2424

14266

4.33

257.34

14.2

8.7

3.67

4.00

e9/l

14.50

2273

12573

Migraine with aura

7415

54354

1.93

257.08

8.0

8.7

3.92

3.95

e9/l

0.52

6580

47645

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

1436

7023

8.02

255.20

19.3

6.1

3.95

4.42

e9/l

11.56

1330

5996

Mental and behavioural disorders due to alcohol, excluding acute intoxication

13022

102971

1.60

255.12

11.5

9.2

4.61

4.15

e9/l

73.29

11373

90131

Benign neoplasm: Sigmoid colon

4603

30852

2.34

254.92

10.1

6.3

4.25

4.32

e9/l

1.12

4035

26336

Paroxysmal tachycardia

6876

41602

1.93

254.69

9.5

8.7

4.17

3.80

e9/l

32.89

6079

36108

Other chronic obstructive pulmonary disease, including avohilmo

14784

98918

1.57

254.63

10.0

9.1

5.07

4.16

e9/l

277.82

13040

85678

Suicide or other Intentional self-harm

7445

54905

1.94

253.40

15.2

8.9

4.38

4.00

e9/l

37.97

6592

48289

Pleural effusion

4195

27794

2.51

253.27

16.2

8.3

4.68

4.30

e9/l

15.63

3801

23930

Injury, poisoning and certain other consequences of external causes

20383

83424

1.44

253.11

9.2

8.5

4.13

3.99

e9/l

12.38

17897

72593

Deposits [accretions] on teeth

2290

12788

4.38

252.83

25.9

8.0

3.87

3.96

e9/l

1.16

2115

11021

Malignant neoplasm of rectum, excluding all cancers (controls excluding all cancers)

3299

20500

2.79

252.33

16.6

6.3

3.89

4.38

e9/l

29.41

2909

17521

Generalized anxiety disorder

4732

32043

2.32

252.24

9.4

8.0

3.97

e9/l

0.09

4058

28287

Secondary hypertension

2406

13508

3.42

252.20

14.2

8.7

4.47

3.86

e9/l

29.82

2193

11673

Type 2 diabetes

31914

162706

1.35

252.06

10.3

8.9

4.66

3.95

e9/l

307.65

27929

142460

Anterior Iridocyclitis

5983

42845

2.15

251.68

12.0

9.2

4.06

4.09

e9/l

0.52

5521

37425

Acute and subacute iridocyclitis

5671

40219

2.20

250.73

11.9

9.2

4.05

4.08

e9/l

0.58

5233

35114

Malignant neoplasm of respiratory system and intrathoracic organs, excluding all cancers (controls excluding all cancers)

6161

36240

1.99

250.59

14.9

6.1

4.88

4.42

e9/l

27.62

5499

30801

Gonarthrosis,primary

27096

144956

1.39

249.76

8.4

9.4

4.16

4.14

e9/l

0.50

23773

126349

Soft tissue disorders related to use, overuse and pressure

7738

57498

1.89

249.18

9.0

9.4

4.18

4.09

e9/l

2.71

6769

49909

Benign neoplasm: Rectum

4485

30110

2.36

248.73

10.0

6.4

4.19

4.32

e9/l

3.23

3900

25764

Demyelinating diseases of the central nervous system

2776

17078

3.61

248.25

14.0

8.8

3.75

4.01

e9/l

10.32

2582

15057

Mental and behavioural disorders due to alcohol

15093

118445

1.53

247.83

11.2

9.0

4.57

4.13

e9/l

80.40

13217

103574

Mixed connective tissue disease

2099

12184

5.58

247.47

15.3

8.8

3.79

4.01

e9/l

5.14

1990

10651

Other cataract

12430

75808

1.62

247.21

10.3

9.2

4.34

4.10

e9/l

22.09

10958

65449

Persons encountering health services for specific procedures, not carried out

2391

13992

3.85

246.52

12.8

8.1

4.35

4.04

e9/l

7.48

1972

12121

Other CVD (FINNGEN)

3237

15630

2.75

245.85

12.7

8.6

4.57

3.87

e9/l

23.72

2894

13477

Other chronic obstructive pulmonary disease

11822

77094

1.64

245.80

10.5

9.1

5.16

4.17

e9/l

258.68

10496

66355

Bacterial pneumonia (organism specified)

12738

91806

1.59

243.73

15.1

8.4

4.81

4.16

e9/l

121.14

11401

79398

Alcohol use disorder, ICD-based

12009

94708

1.62

243.54

11.6

9.2

4.60

4.14

e9/l

67.23

10500

82944

Other benign neoplasms of skin

9695

72516

1.69

243.32

9.4

6.5

4.11

4.23

e9/l

5.06

8515

62233

Polyneuropathies and other disorders of the peripheral nervous system

5896

42360

2.13

242.19

12.0

9.0

4.26

4.24

e9/l

0.32

5296

36782

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

12784

69115

1.58

241.91

9.3

6.4

4.14

4.28

e9/l

8.86

11066

58852

Retention of urine

9116

58280

1.74

241.59

10.5

8.7

4.69

4.31

e9/l

31.68

7975

50521

Atopic dermatitis

17487

122499

1.48

241.33

8.4

8.7

4.00

3.99

e9/l

0.31

15279

107263

Other and unspecified effects of external causes

8181

61714

1.84

241.29

9.6

9.0

4.24

4.01

e9/l

14.16

7221

54120

Sequelae with surgical and medical care as external cause

5597

40138

2.22

240.55

11.9

9.0

4.40

4.14

e9/l

11.17

5036

34896

Obesity, other/unspecified

9941

77142

1.73

239.26

9.2

8.9

4.59

3.97

e9/l

131.84

8605

67785

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

12550

67974

1.58

239.06

9.3

6.4

4.15

4.29

e9/l

8.18

10863

57866

Hard cardiovascular diseases

23359

126555

1.42

239.02

9.1

9.6

4.48

4.05

e9/l

112.91

20488

110029

Pacemaker

8568

63093

1.79

238.86

8.3

8.6

4.51

4.39

e9/l

4.08

7568

54316

ILD, hospital admissions 3, with pneumonia sepsis

2322

13546

3.75

238.45

18.5

7.6

5.12

4.14

e9/l

60.28

2174

11638

Benign neoplasm: Ascending colon

3306

21078

2.76

235.47

10.3

6.3

4.19

4.33

e9/l

2.80

2900

18012

Diabetes, varying definitions

33493

173354

1.32

234.74

10.4

8.9

4.62

3.95

e9/l

307.65

29310

151755

Diabetes mellitus

33654

174026

1.32

234.70

10.3

8.9

4.63

3.95

e9/l

307.65

29451

152355

L01XE Protein kinase inhibitors

1779

10123

7.80

234.66

38.6

9.0

3.59

4.15

e9/l

16.86

1756

8820

Later onset COPD, excluding more controls

5430

29487

2.07

234.03

9.2

7.0

5.28

4.13

e9/l

137.41

4766

24872

Drug-induced neutropenia

2186

13093

5.03

233.61

34.6

9.1

3.20

4.06

e9/l

81.05

2107

11436

Bacterial intestinal infections, IBD co-morbidities

5127

36009

2.18

232.28

15.6

8.6

4.54

4.17

e9/l

16.57

4636

31245

Lymphoid leukaemia

1609

8417

5.31

231.60

30.5

6.3

3.47

4.36

e9/l

28.81

1519

7166

Diffuse large B-cell lymphoma, helper endpoint

1322

6543

8.27

231.26

27.6

6.3

3.58

4.36

e9/l

33.60

1249

5622

Diffuse large B-cell lymphoma, excluding all cancers (controls excluding all cancers)

1322

6543

8.27

231.26

27.6

6.3

3.58

4.36

e9/l

33.60

1249

5622

Other diseases of liver

5061

35850

2.25

229.75

11.5

9.2

4.11

4.06

e9/l

0.88

4506

31296

Intracranial injury

17150

136579

1.46

228.58

8.6

8.9

4.25

4.14

e9/l

6.95

15058

119026

Conduction disorders

8090

50362

1.77

228.20

8.8

9.0

4.46

4.11

e9/l

26.99

7012

43461

Other gastritis (incl. Duodenitis)

6421

46964

1.95

227.40

10.7

8.9

4.25

4.18

e9/l

1.42

5817

40563

Injuries to the knee and lower leg

39262

197336

1.29

227.36

8.9

9.0

4.19

4.08

e9/l

15.31

34401

172690

Other diseases of blood and blood-forming organs

2073

12131

4.58

227.27

17.6

8.6

4.69

4.15

e9/l

7.73

1893

10549

Other necrotizing vasculopathies

2122

12493

4.42

226.90

18.2

8.7

4.92

4.16

e9/l

33.92

1986

10833

Subjective visual disturbances

6984

52264

1.95

226.52

9.7

9.0

3.97

4.07

e9/l

3.38

6111

45596

Other specified/unspecified systemic involvement of connective tissue

1887

10872

5.36

223.89

14.8

8.7

3.81

3.99

e9/l

3.47

1794

9494

Panic disorder

4536

31168

2.22

223.30

9.5

8.0

4.17

3.98

e9/l

6.04

3894

27543

Inflammatory diseases of female pelvic organs

18933

119464

1.46

223.12

8.6

8.5

4.04

3.94

e9/l

7.59

16637

104954

Other and unspecified polyneuropathies, also in other diseases

5106

36313

2.19

223.09

11.4

9.0

4.30

4.26

e9/l

0.59

4592

31527

Type 2 diabetes, definitions combined

30141

155250

1.33

222.73

10.3

8.9

4.66

3.95

e9/l

307.65

26279

135828

Polyuria

6110

44650

2.00

222.22

10.2

8.7

4.22

e9/l

0.06

5288

38806

Statin medication

22975

108397

1.38

220.98

10.0

9.5

4.29

3.92

e9/l

97.48

20118

95738

Temporomandibular joint disorders, including avohilmo

12645

101835

1.58

220.47

8.5

8.7

3.82

3.99

e9/l

16.45

11359

89376

Injuries to the abdomen, lower back, lumbar spine and pelvis

11068

86965

1.62

220.18

9.7

8.8

4.36

4.17

e9/l

11.31

9669

75662

Direct fill therapy

3977

27207

2.53

220.10

21.2

9.1

4.11

4.01

e9/l

1.96

3658

23709

Type 2 diabetes, strict (exclude DM1)

30220

155915

1.33

219.83

10.2

9.0

4.66

3.96

e9/l

307.65

26347

136420

Melanocytic naevi

7820

58846

1.76

219.77

10.4

6.7

3.90

4.15

e9/l

19.26

6935

50992

Non-small cell lung cancer, excluding all cancers (controls excluding all cancers)

3875

23936

2.25

219.77

15.5

6.0

4.91

4.45

e9/l

18.33

3444

20316

Cellulitis

6128

44867

1.98

219.46

12.9

9.0

4.39

4.08

e9/l

17.75

5470

39089

Colorectal adenocarcinoma

5216

37203

2.12

219.39

16.5

8.6

3.92

4.32

e9/l

29.37

4747

32142

Appendectomy

20156

163489

1.42

219.27

9.7

9.0

4.37

4.02

e9/l

64.46

17763

143698

Reactive arthropathies, FINNGEN

2193

12855

3.59

218.83

13.0

8.6

4.09

4.05

e9/l

0.38

1997

11116

Ischemic heart diseases

23182

123339

1.40

218.64

9.0

9.6

4.41

4.06

e9/l

80.55

20454

107136

Propionic acid derivatives

9972

37787

1.60

218.39

8.3

10.3

4.17

4.20

e9/l

0.64

8725

32798

Schizoaffective disorder

2420

14798

3.55

218.09

32.9

8.1

4.40

3.98

e9/l

19.97

2217

13019

Abnormal serum enzyme levels

7929

59706

1.80

216.81

10.2

9.0

4.31

4.34

e9/l

0.45

6910

51964

Senile cataract

18269

94111

1.45

216.58

10.4

9.3

4.34

4.08

e9/l

34.54

16080

81475

Type 2 diabetes, definitions combined, including avohilmo

30363

155566

1.33

215.69

10.3

9.0

4.64

3.95

e9/l

307.65

26486

136127

Psoriasis (vulgaris), strict definition

1102

5352

15.63

214.75

17.3

9.2

3.89

4.09

e9/l

3.79

1085

4665

Exposure to other specified factors

22677

181153

1.38

214.60

9.0

9.1

4.13

4.07

e9/l

2.77

19794

158856

L01XX Other antineoplastic agents

1673

9423

5.88

213.28

30.3

8.8

5.17

4.21

e9/l

10.34

1603

8142

Symptoms and signs involving speech and voice

9248

72381

1.72

213.26

8.9

9.0

4.05

4.10

e9/l

1.27

8124

63069

Ulcerative ileocolitis

1399

7364

7.17

213.05

18.1

8.9

3.87

4.07

e9/l

3.39

1355

6462

Ischaemic heart disease, wide definition

22778

121269

1.39

211.90

8.9

9.6

4.42

4.06

e9/l

85.61

20039

105369

Essential (haemorrhagic) thrombocythaemia

1167

5714

9.24

211.72

22.2

6.3

4.68

4.28

e9/l

2.56

1097

4903

Adverse effects, not elsewhere classified

5765

42237

2.03

211.52

9.6

9.0

4.22

3.99

e9/l

11.27

5106

36970

Ovarian cyst

12051

55526

1.59

211.43

8.5

8.7

4.03

4.01

e9/l

0.52

10616

48685

Other symptoms and signs involving the nervous and musculoskeletal systems

12164

98104

1.58

211.36

9.3

9.0

4.05

4.08

e9/l

0.74

11274

85480

Reactive arthropathies

2661

16511

2.95

211.04

12.6

9.1

4.10

4.08

e9/l

0.16

2420

14317

Mental and behavioural disorders due to multiple drug use and use of multiple drugs and use of other psychoactive substances

2185

12908

3.45

210.78

21.4

8.9

4.38

4.00

e9/l

10.90

1941

11393

Pain in thoracic spine

4422

30664

2.20

210.73

9.2

3.99

4.01

e9/l

0.16

4025

26653

10614

79367

1.64

209.92

9.6

8.7

4.15

4.32

e9/l

11.56

9355

68425

Migraine without aura

6087

44633

1.91

208.72

8.0

8.6

3.92

3.91

e9/l

0.20

5432

39227

Cervicalgia

5909

43187

1.94

207.86

8.2

9.2

4.05

4.06

e9/l

0.18

5255

37382

Other diseases of intestine

3374

22292

2.55

207.50

13.0

8.7

4.47

4.18

e9/l

8.84

3007

19293

Ulcerative proctitis

1936

11287

4.17

207.46

12.9

8.7

3.89

4.06

e9/l

3.63

1773

9912

Follicular lymphoma

1261

6395

7.37

207.05

22.3

6.4

3.42

4.28

e9/l

50.63

1189

5479

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

5925

39215

1.91

206.77

11.0

8.2

4.04

3.94

e9/l

2.83

5132

34439

Glomerular disorders in diseases classified elsewhere

3242

21480

2.70

205.79

14.5

9.0

4.91

4.19

e9/l

46.39

2978

18730

Atopic dermatitis, strict definition with reimbursement

9223

69608

1.66

205.60

9.1

8.6

3.98

3.96

e9/l

0.27

8208

60916

Exclusions for E4_PCOS_CONSORTIUM

23220

124330

1.38

204.93

10.1

8.5

3.98

3.99

e9/l

0.40

20306

109107

Rheumatism, unspecified

4188

29257

2.33

204.29

9.4

4.01

3.93

e9/l

1.39

3787

25365

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

2914

18407

2.58

203.48

16.2

6.0

3.94

4.44

e9/l

24.52

2645

15618

Deforming dorsopathies

8138

62577

1.72

203.28

9.4

9.2

4.11

4.03

e9/l

2.71

7279

54223

Carbimazole or st.post thyroidectomy, condition for graves disease

5968

44407

1.99

203.25

9.3

9.1

3.84

4.00

e9/l

7.20

5169

38845

Somatoform disorder

4781

34065

2.13

202.96

9.8

8.7

3.96

3.99

e9/l

0.49

4273

29844

AV-block

4603

28918

2.04

202.51

8.7

8.6

4.56

4.26

e9/l

10.58

3992

24833

In situ neoplasms

9946

78934

1.65

202.26

10.1

8.6

4.07

4.17

e9/l

4.59

8737

68586

Artificial opening status

1621

9179

5.62

202.19

20.7

9.0

4.50

4.15

e9/l

6.07

1478

7877

SLE (Finngen)

1177

5907

8.56

202.01

18.9

7.4

3.76

4.01

e9/l

3.38

1119

5068

Sleep disorders

6214

46227

1.91

201.74

9.8

8.9

4.11

4.05

e9/l

1.48

5445

40608

Other complications of surgical and medical care, not elsewhere classified

2862

18533

2.89

201.52

14.9

8.5

4.17

4.02

e9/l

2.60

2602

16123

Cervicobrachial syndrome

6425

47859

1.85

200.57

7.8

9.3

4.01

3.99

e9/l

0.20

5787

41601

Hyperkinetic disorders, excluding more controls

2993

18411

2.45

200.49

8.1

6.7

3.94

3.87

e9/l

0.98

2582

16204

Localized swelling, mass and lump of skin and subcutaneous tissue

8847

69217

1.70

200.43

11.0

9.0

3.99

4.11

e9/l

4.97

7967

60203

Allergic rhinitis

9428

73381

1.65

200.41

7.5

9.1

3.89

3.95

e9/l

2.40

8392

64408

Disorders of choroid and retina

23487

146539

1.36

199.27

9.2

4.34

4.14

e9/l

27.71

20618

127524

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum, excluding all cancers (controls excluding all cancers)

2568

15898

2.81

199.24

17.2

6.1

3.90

4.40

e9/l

22.99

2341

13561

Skin changes due to chronic exposure to nonionizing radiation

9892

74306

1.64

198.41

9.4

8.6

4.14

4.34

e9/l

12.97

8703

64043

Actinic keratosis

9596

72100

1.66

197.95

9.4

8.6

4.16

4.35

e9/l

12.29

8436

62099

Problems related to lifestyle

3078

20041

2.56

197.69

12.7

8.3

4.73

4.06

e9/l

39.47

2792

17561

Diseases of salivary glands

5550

40540

1.95

197.57

10.4

8.4

4.08

4.06

e9/l

0.23

4962

35311

Streptococcal septicaemia

2363

14549

3.10

196.40

17.1

7.4

4.81

4.12

e9/l

22.89

2132

12501

Carpal tunnel syndrome

18018

137149

1.42

196.19

8.4

9.2

4.11

4.07

e9/l

2.05

16118

119617

Other neurological diseases

20756

142006

1.38

195.50

8.8

9.1

4.31

4.16

e9/l

12.88

18458

123301

Collagenous colitis

2572

16506

3.19

195.43

13.2

8.9

4.23

4.06

e9/l

2.75

2307

14326

Injuries to the thorax

12373

100456

1.52

195.34

9.4

9.1

4.35

4.20

e9/l

7.53

10864

87436

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

30530

162650

1.30

194.41

10.0

9.0

4.68

3.94

e9/l

307.65

26722

142287

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

2602

16676

3.03

193.44

15.7

8.5

4.33

4.04

e9/l

7.62

2357

14532

Complications of internal orthopaedic prosthetic devices, implants and grafts

5974

44506

1.91

193.33

10.5

8.5

4.35

4.20

e9/l

5.28

5321

38309

Hernia of abdominal wall

12593

102931

1.53

192.91

9.9

9.2

4.40

4.16

e9/l

23.33

11216

89688

Phobic anxiety disorders

3969

27257

2.18

192.47

11.2

8.1

4.13

3.95

e9/l

5.32

3399

24054

Presence of other functional implants

15983

93999

1.45

191.68

9.2

8.9

4.41

4.17

e9/l

25.92

14219

80625

Adenocarcinoma and papilloma adenocarcinoma of rectum, excluding all cancers (controls excluding all cancers)

2479

15371

2.79

190.89

17.0

6.1

3.91

4.40

e9/l

21.71

2260

13113

Pain and other conditions associated with female genital organs and menstrual cycle

6195

44304

1.84

190.28

7.6

8.6

3.92

3.95

e9/l

0.74

5501

38961

Zoster [herpes zoster]

4761

34327

2.09

189.98

14.7

8.7

4.20

4.18

e9/l

0.18

4307

29719

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

7846

36132

1.67

189.85

9.7

6.5

4.30

4.50

e9/l

8.00

6870

30957

Speech therapy

7530

58359

1.77

189.67

11.2

9.1

4.21

4.10

e9/l

3.46

6798

50747

Nonorganic sleeping disorders

5458

40204

1.96

189.18

9.8

9.0

4.11

4.03

e9/l

1.64

4772

35307

Chronic pancreatitis

3362

22784

2.48

189.08

15.4

9.3

4.53

4.12

e9/l

16.73

3037

19780

Bronchiectasis

2245

13986

3.37

188.91

12.4

9.0

4.60

4.08

e9/l

17.12

2077

12037

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

2946

19024

2.47

188.33

13.9

6.2

4.40

4.41

e9/l

0.11

2583

16226

Extracorporeal dialysis

1756

10365

4.49

187.77

20.0

9.3

4.89

4.19

e9/l

22.98

1675

9018

Other viral hepatitis

1937

11584

3.63

185.90

16.3

9.3

3.95

4.02

e9/l

0.60

1752

10217

Other disorders of ear

28314

164576

1.31

184.71

8.7

9.3

4.11

e9/l

0.13

24977

143349

Malignant neoplasm of bronchus and lung, excluding all cancers (controls excluding all cancers)

5193

31031

1.87

184.64

14.9

6.0

4.98

4.44

e9/l

31.61

4620

26342

Acute pancreatitis

5304

38879

1.93

184.61

11.5

9.0

4.81

4.14

e9/l

52.52

4714

33781

Anti-inflammatory and antirheumatic products, non-steroids

9770

37796

1.54

184.07

8.4

10.3

4.15

4.20

e9/l

1.13

8535

32806

Other (not insulin) diabetes medications

30317

160134

1.29

181.99

10.0

9.0

4.68

3.97

e9/l

307.65

26437

140050

Voice disturbances

7386

57496

1.76

181.09

8.7

9.1

3.97

4.06

e9/l

3.24

6487

50135

Cardiodefibrillation

9422

75227

1.63

180.97

8.8

9.2

4.41

4.32

e9/l

3.04

8037

65350

Internal derangement of knee

10839

86695

1.52

180.68

8.5

9.0

4.09

4.13

e9/l

0.91

9536

75099

Chronic viral hepatitis

1659

9585

4.08

179.99

16.8

9.4

3.96

4.00

e9/l

0.31

1498

8442

Diabetes medication

33058

177152

1.28

179.49

10.1

8.9

4.65

3.96

e9/l

307.65

28924

155036

Cervical disc disorders

10345

83098

1.56

179.45

8.4

9.5

4.14

4.10

e9/l

1.16

9326

72084

Phlebitis and thrombophlebitis (not including DVT)

6243

47398

1.84

179.03

12.6

9.0

4.05

4.13

e9/l

1.71

5523

41157

Thrombocytopenia, unspecified

2023

12492

3.57

178.80

24.3

8.6

3.53

4.19

e9/l

24.88

1877

10859

Excessive, frequent and irregular menstruation

12874

58434

1.50

178.12

8.6

3.99

4.01

e9/l

0.35

11402

51186

Viral hepatitis

2198

13759

3.15

177.07

15.7

9.2

3.95

4.03

e9/l

0.77

1966

12120

Malignant neoplasm of head and neck, excluding all cancers (controls excluding all cancers)

2559

16209

2.56

176.44

11.9

6.4

4.26

4.36

e9/l

1.41

2302

13865

Missing teeth due to accident, extraction or parodontitis

3212

21841

2.44

176.33

15.0

8.6

4.19

4.14

e9/l

0.64

2963

18976

Calcific aortic valvular stenosis

7366

55649

1.69

176.23

8.5

8.4

4.64

4.42

e9/l

10.46

6448

47877

Calcific aortic valvular stenosis, operated

7366

55649

1.69

176.23

8.5

8.4

4.64

4.42

e9/l

10.46

6448

47877

Diffuse large B-cell lymphoma

1322

7388

6.62

176.00

27.6

9.0

3.58

4.23

e9/l

24.95

1249

6428

Unspecified kidney failure

2560

16383

2.64

175.94

14.1

8.1

4.97

4.32

e9/l

26.15

2286

14116

Calcific aortic valvular stenosis, diagnosis (helper)

7351

55539

1.69

175.69

8.5

8.4

4.64

4.43

e9/l

10.25

6434

47780

Operations 2 for CAVS

7351

55539

1.69

175.69

8.5

8.4

4.64

4.43

e9/l

10.25

6434

47780

Need for other prophylactic measures

1682

10026

4.46

175.63

17.9

9.3

4.32

4.06

e9/l

3.50

1306

8755

Malignant neoplasm of breast, HER-negative

5493

41161

1.93

175.28

10.7

8.6

3.68

4.07

e9/l

35.12

4918

35339

Benign neoplasm of other and ill-defined parts of digestive system

4790

35307

2.06

175.27

10.8

9.1

4.25

4.15

e9/l

2.13

4264

30677

Ascites

2016

12342

3.29

175.23

21.7

8.6

4.07

4.11

e9/l

0.30

1817

10638

Persistent mood disorders

5584

41578

1.86

175.22

10.3

8.7

4.22

4.03

e9/l

7.83

4776

36380

Preparatory care for dialysis

1292

7198

6.98

174.95

16.8

9.4

4.63

4.19

e9/l

8.76

1221

6292

Diabetes, insulin treatment (Kela reimbursement)

31800

171399

1.28

174.94

9.9

9.1

4.68

3.97

e9/l

307.65

27826

149797

Benign neoplasm: Transverse colon

2490

15946

2.74

174.86

10.3

6.3

4.32

e9/l

0.00

2216

13626

Other viral diseases

8514

67005

1.63

174.50

13.2

8.9

3.99

4.02

e9/l

0.43

7619

58760

Artificial joint operation, meniscal resection

27374

159374

1.31

173.89

8.6

9.4

4.12

4.14

e9/l

0.89

24026

139032

Calcific aortic valvular stenosis, including rheumatic fever

7375

55768

1.69

173.86

8.5

8.4

4.64

4.43

e9/l

10.13

6453

47977

Explicit bacterial Sepsis

2816

18487

2.50

173.85

16.7

8.1

4.72

4.11

e9/l

23.36

2540

15964

Acute and transient psychotic disorders

3432

23656

2.31

173.80

26.6

8.2

4.40

3.99

e9/l

19.76

3086

20725

Fenamates

4674

22199

1.90

173.75

8.9

10.2

4.05

4.18

e9/l

3.62

4040

19377

Biguanides

29540

159790

1.29

173.36

9.8

9.1

4.69

3.98

e9/l

307.65

25730

139792

Other and unspecified drugs and medicaments

2399

15567

3.05

173.28

15.9

8.7

4.35

4.08

e9/l

6.39

2178

13562

Congenital malformations, deformations and chromosomal abnormalities

17969

146357

1.38

172.93

9.3

9.0

4.06

4.03

e9/l

1.11

15904

128483

Iron deficiency anaemia secondary to blood loss (chronic)

4302

30840

2.05

172.38

12.0

8.5

4.35

4.19

e9/l

3.80

3930

26703

Other CVD

4819

35122

1.95

172.21

11.4

8.3

4.50

4.34

e9/l

2.52

4289

30240

Lymphoid leukaemia

1609

9449

4.32

171.85

30.5

8.8

3.47

4.24

e9/l

22.32

1519

8180

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

8254

64414

1.63

169.60

11.3

8.3

4.14

3.98

e9/l

6.52

7219

56664

Insulin, intermediate and long-acting

15487

127974

1.42

169.39

9.8

9.1

4.89

4.14

e9/l

225.71

13720

111293

Other enthesopathies

8621

68360

1.61

168.65

7.9

9.4

4.06

4.02

e9/l

0.83

7686

59577

Benign neoplasm: Stomach

2471

15913

2.66

168.04

10.6

6.4

4.11

4.25

e9/l

1.95

2203

13628

Other retinal disorders

17508

119435

1.39

167.90

8.9

9.1

4.47

4.18

e9/l

38.98

15376

103588

Hypokalaemia

3141

21402

2.36

167.55

12.8

8.6

4.69

4.06

e9/l

31.96

2804

18594

Early onset COPD

6017

45836

1.81

167.44

12.0

9.3

5.02

4.09

e9/l

135.88

5417

39860

Hypertensive heart and/or renal disease

6699

39338

1.69

167.34

8.6

9.0

4.81

4.05

e9/l

101.51

5792

33961

Chronic periodontitis, complicated

2601

17344

2.82

166.72

17.7

9.2

4.52

4.14

e9/l

12.00

2333

15179

Multiple myeloma, excluding all cancers (controls excluding all cancers)

1264

6787

4.61

166.41

42.0

6.1

3.14

4.39

e9/l

89.17

1192

5784

Disorders of mineral metabolism

2293

14753

2.95

166.33

14.6

8.9

4.31

4.03

e9/l

5.93

2104

12848

Cardiomyopathy

4614

33439

1.92

165.85

10.9

9.2

4.50

4.13

e9/l

18.96

4042

28916

COPD, hospital admissions

11861

82477

1.49

165.85

10.5

9.0

5.15

4.21

e9/l

240.98

10537

71294

Other skin changes

4500

33000

2.04

165.37

11.5

8.8

4.08

4.18

e9/l

1.98

4128

28625

Other disorders of white blood cells

1631

9766

4.19

165.10

19.6

8.6

4.53

4.14

e9/l

4.28

1534

8524

Migraine with aura and triptan purchases

4441

32332

2.01

165.07

8.0

8.8

3.95

e9/l

0.08

3956

28502

Benign neoplasm: Caecum

2485

16123

2.65

164.95

10.2

6.3

4.20

4.32

e9/l

1.72

2201

13740

KRA_PSY_EATING, excluding more controls

2528

16153

2.47

164.87

11.3

6.3

3.78

3.94

e9/l

3.50

2200

14277

Multiple myeloma and malignant plasma cell neoplasms

1252

6727

4.60

164.51

42.2

6.1

3.14

4.39

e9/l

87.64

1182

5733

Viral pneumonia (unknown virus, not influenza)

1936

11940

3.25

164.45

15.5

8.9

4.35

4.05

e9/l

6.82

1662

10444

Benign neoplasm of other and unspecified endocrine glands

3235

22148

2.26

163.98

8.9

6.7

4.42

4.18

e9/l

5.38

2854

19059

Suggestive for eosinophilic asthma

2572

17030

2.70

163.74

9.9

9.1

4.32

4.07

e9/l

6.78

2278

14805

Thyrotoxicosis with diffuse goitre

4052

29228

2.11

163.39

9.5

8.9

3.77

3.99

e9/l

9.64

3590

25552

Unspecified fall

13755

114072

1.44

162.54

9.1

9.0

4.28

4.13

e9/l

9.30

11796

99365

Benign neoplasm: Colon, unspecified

6354

49127

1.78

162.39

9.9

9.0

4.36

4.24

e9/l

3.29

5497

42655

Irregular menses

14388

98077

1.44

162.22

9.3

8.4

3.96

3.90

e9/l

2.61

12860

86309

Other symptoms and signs involving the digestive system and abdomen

4614

33710

1.93

162.13

11.9

8.4

4.04

3.94

e9/l

2.20

4270

29066

Intestinal adhesions without obstruction

2287

14661

2.79

162.09

14.2

8.7

4.59

4.16

e9/l

10.90

2066

12689

Systemic lupus erythematosus

1177

6530

7.11

161.39

18.9

8.5

3.76

3.98

e9/l

2.96

1119

5717

COPD, early/later onset

11921

82967

1.48

161.25

10.4

9.0

5.16

4.21

e9/l

245.07

10583

71719

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

2556

16590

2.45

160.72

13.9

6.2

4.35

4.38

e9/l

0.21

2250

14176

Epilepsy

8764

69530

1.56

160.33

12.3

9.3

4.14

4.11

e9/l

0.60

7714

60360

Acute pancreatitis (for exclusion)

5304

39831

1.85

160.33

11.5

9.1

4.81

4.18

e9/l

47.03

4714

34634

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

2191

14017

2.91

160.15

13.9

8.6

4.70

4.20

e9/l

18.96

2028

12142

Other diseases of lip and oral mucosa

4397

32094

1.98

159.39

12.3

8.6

4.04

4.09

e9/l

0.73

3957

27874

Other specified and unspecified personality disorders

2700

18111

2.53

158.62

16.1

8.7

4.31

4.00

e9/l

9.48

2360

15977

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

7427

34174

1.61

158.57

9.5

6.4

4.34

4.52

e9/l

6.29

6491

29249

Insomnia

4483

32959

1.98

158.57

10.0

9.0

4.10

4.04

e9/l

1.18

3939

28941

Other metabolic disorders

3718

26535

2.15

158.36

12.5

8.8

3.91

3.93

e9/l

0.15

3323

23224

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

16347

136839

1.39

158.05

8.6

8.9

3.91

4.00

e9/l

5.95

14153

120203

SLE, ICD10

1136

6321

7.92

157.83

18.9

8.7

3.76

3.97

e9/l

2.76

1077

5547

SLE, strict definition

1136

6321

7.92

157.83

18.9

8.7

3.76

3.97

e9/l

2.76

1077

5547

Malignant melanoma, excluding all cancers (controls excluding all cancers)

4155

29797

1.95

157.77

11.6

6.3

4.07

4.33

e9/l

9.10

3613

25491

Trochanteric bursitis

3810

27374

2.13

157.46

8.5

9.2

4.10

4.01

e9/l

1.67

3301

23700

Dialysis

1225

6834

5.54

157.31

18.7

9.3

4.61

4.04

e9/l

12.49

1168

5937

Mental and behavioural disorders due to sedatives or hypnotics

1998

12561

3.07

157.23

15.8

9.0

4.45

4.03

e9/l

10.91

1750

11027

Superficial injury of head

6209

47667

1.73

156.37

8.8

9.0

4.24

4.12

e9/l

3.91

5385

41416

Polycythaemia vera

998

5085

6.00

155.97

23.1

6.0

6.46

4.33

e9/l

26.36

941

4339

Open wound of head

14627

121202

1.40

155.92

9.1

9.2

4.33

4.16

e9/l

12.81

12791

105634

Other and unspecified urticaria

5563

42395

1.82

155.54

9.5

9.0

4.09

3.99

e9/l

2.56

5019

37029

Cerebrovascular diseases

20726

128554

1.34

155.52

8.9

9.3

4.51

4.14

e9/l

72.24

18091

111620

Migraine, single triptan purchase ok & required. ICD-code if available is included

24426

144687

1.31

155.23

7.7

9.3

3.89

3.98

e9/l

9.63

21628

127179

Triptan medication for migraine, single purchase ok

24426

144687

1.31

155.23

7.7

9.3

3.89

3.98

e9/l

9.63

21628

127179

Cholangitis (primary sclerosing, PSC)

1732

10531

3.37

154.75

18.7

8.8

4.33

4.11

e9/l

2.85

1609

9124

Hallux valgus (acquired)

9618

55998

1.53

154.73

8.7

3.95

4.04

e9/l

3.09

8416

48372

Malignant neoplasm of colon

3779

27074

2.09

154.50

16.1

8.6

4.03

4.30

e9/l

8.36

3424

23372

Allergic conjunctivitis

17029

143561

1.37

153.96

8.6

9.0

3.91

4.00

e9/l

6.26

14765

126250

Polycystic ovarian syndrome, consortium definition

22308

117183

1.33

153.93

8.9

8.4

4.02

3.95

e9/l

4.56

19822

102519

Coronary atherosclerosis

19138

106244

1.36

153.75

8.6

9.6

4.51

4.10

e9/l

92.47

16821

91972

Follicular lymphoma, hilmo

1261

7262

5.83

153.24

22.3

9.3

3.42

4.16

e9/l

40.03

1189

6308

Injuries to the ankle and foot

20915

165404

1.32

153.10

9.3

9.0

4.13

4.03

e9/l

8.01

18467

145234

Alcohol abuse, main dg, excluding more controls

4018

28793

1.95

152.53

10.2

8.3

4.54

4.05

e9/l

27.53

3526

25239

Human immunodeficiency virus [HIV] disease

691

3217

35.20

151.69

19.4

9.8

3.08

4.11

e9/l

54.49

681

2833

Fracture of rib(s), sternum and thoracic spine

7686

60940

1.61

151.38

9.4

9.0

4.43

4.23

e9/l

7.50

6744

52993

Malignant neoplasm of mesothelium and soft tissue, excluding all cancers (controls excluding all cancers)

1761

10694

3.08

150.90

19.3

6.3

4.26

4.32

e9/l

0.29

1585

9133

Ventral hernia

6406

49845

1.71

150.65

10.6

9.0

4.43

4.16

e9/l

16.54

5779

43246

Degeneration of macula and posterior pole

12020

82313

1.46

150.48

8.6

8.9

4.42

4.27

e9/l

7.88

10464

70930

Conjunctivitis (acute, non atopic)

7822

62154

1.61

150.46

10.2

9.2

4.07

4.03

e9/l

0.47

6985

54328

Heartburn

2866

19478

2.29

150.44

8.8

8.5

4.02

e9/l

0.00

2569

16888

Enteropathic arthropathies

795

3849

10.80

150.42

19.9

9.0

4.05

e9/l

0.00

769

3374

Nonalcoholic fatty liver disease

2580

17502

2.62

150.32

10.9

9.4

4.15

3.99

e9/l

3.33

2285

15350

Mixed and other personality disorders

2372

15668

2.64

150.07

14.1

8.8

4.27

3.97

e9/l

9.11

2028

13863

Enterocolitis due to Clostridium difficile

2816

19107

2.32

150.02

18.4

8.4

4.83

4.24

e9/l

18.32

2598

16523

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

2745

18160

2.19

149.39

9.9

5.7

4.51

4.58

e9/l

0.61

2441

15351

Gastroduodenal ulcer

6734

52068

1.63

149.32

10.8

8.7

4.65

4.31

e9/l

17.18

6046

44753

Other disorders of kidney and ureter

3358

23884

2.23

149.31

12.1

9.1

4.47

4.16

e9/l

10.69

3007

20776

Hydronephrosis

3006

20765

2.25

148.06

16.5

8.2

4.55

4.10

e9/l

14.82

2764

17935

Misadventures to patients during surgical and medical care

3790

27506

2.07

147.15

11.8

8.7

4.38

4.08

e9/l

10.14

3451

23968

Idiopathic gout

2304

15211

2.66

146.61

10.3

8.7

4.93

4.34

e9/l

22.31

2037

13173

Hypotension

4012

29105

1.95

146.31

11.3

8.1

4.61

4.38

e9/l

4.14

3557

25066

Human immunodeficiency virus [HIV] disease resulting in other conditions

634

2898

64.94

145.87

19.8

9.8

3.07

4.12

e9/l

49.80

626

2546

Diseases of male genital organs

15195

64333

1.37

145.74

9.7

10.0

4.25

4.26

e9/l

0.09

13404

55987

Other and unspecified types of non-Hodgkin lymphoma, hilmo, excluding all cancers

1115

5976

4.41

145.33

23.8

6.3

3.72

4.37

e9/l

16.40

1029

5131

Fissure and fistula of anal and rectal regions

6712

52469

1.64

145.26

10.1

8.8

4.09

e9/l

0.06

5926

45597

Systemic lupus erythematosus, unspecified

991

5433

8.93

144.71

18.9

8.6

3.72

3.99

e9/l

3.84

940

4776

Fibrosis and cirrhosis of liver

2016

13129

3.03

143.91

13.3

9.0

3.85

4.14

e9/l

5.71

1850

11420

Other disorders of skin and subcutaneous tissue, not elsewhere classified

3818

27772

2.02

143.53

12.1

8.8

4.51

4.14

e9/l

16.51

3522

24116

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

1559

9232

3.13

142.97

16.7

6.1

4.82

4.40

e9/l

7.35

1412

7850

Unspecified privation

2969

20769

2.29

142.65

12.1

8.9

4.37

4.12

e9/l

6.01

2458

18165

Migraine without aura and triptan purchases

4642

34765

1.86

142.44

7.6

8.8

3.91

3.94

e9/l

0.53

4132

30652

Other pleural conditions

2605

17559

2.34

142.31

16.7

8.4

4.61

4.31

e9/l

5.98

2365

15120

Osteoporosis with pathological fracture (FG)

1764

10984

3.07

142.24

13.2

7.8

4.50

4.10

e9/l

8.54

1577

9307

Other/unspecified reactive arthropathies

1922

12383

3.07

142.06

13.2

8.9

4.10

4.06

e9/l

0.34

1754

10896

Weight loss

2611

17947

2.51

142.00

10.6

8.9

4.12

4.13

e9/l

0.02

2345

15560

Gonarthrosis, primary, with knee surgery

15193

106049

1.39

141.81

8.4

9.4

4.21

4.19

e9/l

0.54

13287

91932

Childhood asthma (age<16), excluding more controls

4050

22817

1.82

141.79

8.4

7.3

4.05

3.87

e9/l

5.53

3575

19851

Abnormal findings on diagnostic imaging of other body structures

3407

24564

2.17

141.28

11.8

8.7

4.22

4.06

e9/l

3.19

3026

21299

Malignant neoplasm of ovary, excluding all cancers (controls excluding all cancers)

1746

10900

3.12

141.15

22.2

6.5

3.68

4.06

e9/l

10.32

1531

9308

Hypertensive Heart Disease

5869

36574

1.66

140.88

8.5

8.9

4.81

4.06

e9/l

85.01

5051

31561

Injuries to the shoulder and upper arm

24765

183299

1.28

139.66

8.8

9.2

4.20

4.11

e9/l

7.66

21677

160097

Childhood asthma (age<16)

4050

22896

1.81

139.55

8.4

7.4

4.05

3.87

e9/l

5.29

3575

19918

Postprocedural endocrine and metabolic disorders, not elsewhere classified

3385

24307

2.11

139.05

12.2

8.7

3.90

3.92

e9/l

0.23

3024

21290

Carcinoma in situ of breast, intraductal

2156

14183

2.67

138.86

9.7

6.7

3.55

4.01

e9/l

23.46

1931

12149

Alcohol dependence

7240

57473

1.59

138.45

12.8

9.2

4.66

4.15

e9/l

48.60

6340

50235

Fentanyl

2568

17037

2.19

138.39

20.4

7.4

4.53

4.23

e9/l

6.92

2372

14575

Any event in hilmo or specialist outpatient

310

319

8.72

138.06

9.2

1.9

4.07

3.68

e9/l

1.66

276

283

Atopic dermatitis, strict definition

8643

68760

1.53

137.94

9.0

8.8

3.97

3.95

e9/l

0.21

7658

60390

DVT of lower extremities

5011

38129

1.78

137.37

12.4

8.8

4.24

4.21

e9/l

0.46

4437

33022

Recurring oral aphthae, including avohilmo

3712

27251

2.05

137.32

12.8

8.9

4.01

4.04

e9/l

0.33

3292

23728

Idiopathic pulmonary fibrosis

1928

12369

2.81

137.17

14.7

8.4

4.96

4.36

e9/l

20.29

1805

10679

Asthma and opportunity respiratory infection

1315

7826

4.37

137.04

12.7

9.0

4.90

4.09

e9/l

22.21

1237

6782

Polyarthritis, unspecified

1116

6210

4.58

136.64

16.2

8.8

4.17

4.12

e9/l

0.39

1037

5388

Immunodeficiencies

1434

8757

3.98

136.12

22.3

9.0

4.06

4.03

e9/l

0.23

1367

7642

Chronic diseases of tonsils and adenoids

25288

141242

1.27

136.10

8.6

9.4

3.98

4.03

e9/l

3.23

22335

123726

Covid-19 suspected case

5928

46227

1.69

135.78

10.0

8.6

4.10

4.00

e9/l

2.65

5367

40579

Hodgkin lymphoma

872

4487

6.12

134.55

22.1

6.5

3.47

4.22

e9/l

20.07

802

3883

Systemic sclerosis (FG)

785

3995

9.86

134.33

16.7

8.2

3.86

3.99

e9/l

1.03

759

3430

Post-traumatic stress disorder

2366

15793

2.36

133.85

10.0

7.6

4.17

3.95

e9/l

4.33

2068

13974

Exclusions for E4_PCOS_BROAD

4658

35351

1.84

133.74

11.8

9.3

4.29

4.00

e9/l

13.06

4232

30819

Non-small cell lung cancer

3875

28253

1.88

133.69

15.5

8.5

4.91

4.34

e9/l

28.78

3444

24355

Other and unspecified psoriasis

1835

11844

2.99

133.26

14.2

8.9

4.22

4.12

e9/l

1.28

1674

10352

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

3444

24627

1.96

132.81

11.7

6.3

4.07

4.32

e9/l

6.74

3022

21087

Abnormal weight loss

2354

16084

2.57

132.61

9.9

8.9

4.14

4.15

e9/l

0.05

2112

13947

Endometriosis

10841

53413

1.46

132.36

7.9

8.8

3.95

4.01

e9/l

2.13

9537

46845

All influenza (not pneumonia)

4082

30072

1.85

132.30

12.9

8.2

4.28

3.99

e9/l

12.33

3682

26053

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

9265

49067

1.50

132.18

7.7

7.6

4.04

3.99

e9/l

1.56

8274

43527

Disorders of parathyroid gland

5355

40909

1.73

131.34

11.0

8.7

4.36

4.14

e9/l

7.45

4784

35287

Other disorders of eye and adnexa

3796

28077

1.98

131.34

10.2

9.0

4.00

4.02

e9/l

0.18

3341

24542

Carcinoma in situ of skin of other and unspecified parts of face

1784

11145

2.65

130.99

11.1

5.6

4.31

4.56

e9/l

3.53

1532

9400

Malignant neoplasm of skin

16529

107291

1.35

130.93

9.5

9.0

4.20

4.24

e9/l

1.20

14342

92827

Benign neoplasm: Ascending colon

3306

24111

2.15

130.83

10.3

9.1

4.19

4.20

e9/l

0.12

2900

20939

Candidiasis

3616

26598

2.02

130.82

14.8

8.8

4.32

4.06

e9/l

9.55

3259

23209

Menorrhagia

10872

49811

1.46

130.51

8.3

9.1

3.98

4.01

e9/l

0.73

9609

43611

Chronic lymphocytic leukaemia and small lyphocytis leukaemia, excluding all cancers (controls excluding all cancers)

776

3829

6.15

129.42

29.9

5.9

3.40

4.47

e9/l

38.77

733

3286

Chronic lymphocytic leukaemia, helper endpoint

776

3829

6.15

129.42

29.9

5.9

3.40

4.47

e9/l

38.77

733

3286

Disorders resulting from impaired renal tubular function

1044

5950

5.67

129.09

17.3

9.4

4.65

4.10

e9/l

11.62

978

5217

598

12785

0.33

128.37

6.3

8.8

4.60

4.38

e9/l

1.00

516

11080

Other disorders of eyelid

11695

95314

1.42

128.10

8.6

9.0

4.20

4.19

e9/l

0.22

10198

82494

Other embolism and thrombosis

3435

24984

2.00

128.09

13.3

8.8

4.19

4.17

e9/l

0.22

3004

21684

Glomerulonephritis

2685

18811

2.26

127.32

14.9

9.1

4.44

4.12

e9/l

9.04

2474

16384

Unspecified acute lower respiratory infection

3954

29270

1.86

127.27

13.8

8.9

4.64

4.14

e9/l

29.48

3585

25534

Cervicocranial syndrome

2976

21099

2.10

126.97

7.9

9.2

3.97

4.04

e9/l

0.81

2671

18345

Pollen allergy

5386

41345

1.70

126.95

7.2

9.1

3.79

3.93

e9/l

6.65

4740

36327

Other hammer toe(s) (acquired)

4523

32056

1.79

126.83

8.8

8.7

4.07

4.11

e9/l

0.43

3925

27470

Mental and behavioural disorders due to opioids

1142

6497

3.94

126.74

16.6

8.9

4.29

3.99

e9/l

4.27

1027

5737

Other respiratory disorders and diseases

5010

38339

1.71

126.53

12.0

8.6

5.03

4.29

e9/l

70.80

4529

33037

Other diseases of the respiratory system

5010

38339

1.71

126.53

12.0

8.6

5.03

4.29

e9/l

70.80

4529

33037

Myocardial infarction, without ST-elevation

9903

75595

1.45

126.48

8.1

8.8

4.86

4.34

e9/l

64.63

8530

65354

Other disorders of veins

10746

90214

1.45

126.46

8.6

8.9

4.02

4.08

e9/l

1.60

9083

78687

Fracture of lumbar spine and pelvis

5408

41928

1.69

125.89

10.7

8.5

4.51

4.25

e9/l

8.82

4713

36271

Other obstetric conditions, not elsewhere classified

9441

50393

1.48

125.76

7.7

7.6

4.03

3.98

e9/l

1.54

8429

44709

Benign lipomatous neoplasm

7153

57125

1.54

125.69

8.5

6.7

4.09

4.20

e9/l

3.58

6288

49073

Benign neoplasm: Sigmoid colon

4603

35332

1.83

125.61

10.1

9.1

4.25

4.20

e9/l

0.78

4035

30658

Deviated nasal septum

8991

73857

1.48

125.53

8.3

9.7

4.09

4.18

e9/l

2.86

7871

64513

Immunodeficiency with predominantly antibody defects

848

4602

8.28

125.09

27.3

8.8

3.96

4.01

e9/l

0.30

824

4026

Other dialysis

911

5042

6.91

125.08

18.7

9.9

4.61

4.11

e9/l

9.00

866

4418

Graves disease, strict definition

2791

19878

2.25

124.86

9.4

8.9

3.66

3.97

e9/l

14.04

2449

17486

Benign neoplasm: Rectum

4485

34384

1.84

124.70

10.0

9.1

4.19

4.21

e9/l

0.22

3900

29867

Benign neoplasm: Rectum, anus and anal canal

5051

39274

1.76

123.94

9.8

9.1

4.22

4.21

e9/l

0.05

4386

34130

Other and unspecified disorders of white blood cells

1177

6974

4.28

123.18

21.0

8.7

4.55

4.14

e9/l

3.09

1095

6080

Diseases of appendix

22543

181809

1.27

123.12

8.9

9.1

4.38

4.05

e9/l

63.89

19911

159579

Juvenile rheumatoid arthirtis

773

3956

6.74

123.08

18.9

7.8

4.04

3.91

e9/l

1.06

752

3455

Other diseases of biliary tract

2237

15220

2.43

122.53

18.2

8.8

4.34

4.13

e9/l

3.43

2005

13175

Ulcerative enterocolitis

994

5568

4.87

122.43

17.9

8.6

4.06

4.07

e9/l

0.07

940

4879

Total colectomy

1226

7341

4.01

122.37

17.7

9.2

4.55

4.09

e9/l

8.85

1145

6422

Total colectomy operation

1226

7341

4.01

122.37

17.7

9.2

4.55

4.09

e9/l

8.85

1145

6422

Insulin medication

16970

125849

1.32

122.29

10.5

9.1

4.89

4.03

e9/l

307.65

15089

109561

Autoimmune hyperthyroidism

1729

11056

2.72

121.80

9.6

7.6

3.80

4.02

e9/l

4.19

1537

9516

Pruritus

2919

20856

2.10

121.53

10.2

8.7

4.16

4.04

e9/l

1.58

2653

18165

Other follicular disorders

1998

13338

2.59

121.34

12.9

8.8

4.44

4.04

e9/l

13.34

1829

11720

Appendicitis, broad definition

22354

180978

1.27

121.27

8.9

9.1

4.38

4.05

e9/l

64.37

19737

158855

Benign neoplasm: Adrenal gland

1811

11774

2.68

120.97

9.4

6.5

4.70

4.19

e9/l

10.65

1583

10122

Myocarditis

1376

8182

2.95

120.93

12.9

8.8

4.17

3.85

e9/l

5.06

1251

7088

Dermatophytosis

3358

24695

2.01

120.82

11.8

9.0

4.30

4.15

e9/l

2.61

3070

21457

Gastric ulcer

4498

34043

1.73

120.71

11.2

8.6

4.54

4.29

e9/l

7.42

4039

29270

Abnormal involuntary movements

3510

25994

1.97

120.69

10.1

9.1

4.15

4.10

e9/l

0.64

3099

22621

Obsessive-compulsive disorder

1875

12144

2.50

120.53

15.2

7.9

4.01

3.95

e9/l

0.58

1635

10697

Acute appendicitis

20953

174527

1.28

119.59

8.9

9.1

4.38

4.04

e9/l

61.79

18485

153271

Leiomyoma of uterus

13095

62510

1.37

119.29

8.5

6.7

3.95

4.02

e9/l

2.71

11382

54566

Enthesopathies of lower limb, excluding foot

6016

47617

1.61

119.09

8.3

9.4

3.99

4.00

e9/l

0.22

5315

41400

Other and unspecified mood [affective] disorders

2060

13717

2.39

118.77

11.5

8.0

4.06

3.95

e9/l

1.59

1730

12135

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

2705

18589

1.98

118.61

10.4

5.8

4.78

4.58

e9/l

2.74

2368

15798

Disorders of breast

13947

111532

1.37

118.50

8.8

8.7

3.89

3.96

e9/l

3.29

12270

97876

Persons with potential health hazards related to communicable diseases

10993

91918

1.41

117.72

11.8

8.6

4.00

e9/l

0.00

9855

80739

Other and unspecified tonsillitis

9872

69449

1.42

117.63

9.2

8.4

4.22

3.98

e9/l

19.92

8773

60788

Other peripheral vascular diseases

2183

14942

2.42

117.28

9.1

8.6

3.78

4.06

e9/l

7.66

1977

12984

malignant neoplasm of female genital organs

3865

29396

1.93

117.24

16.7

8.6

3.85

4.04

e9/l

5.41

3467

25404

Valvular operations

3604

26517

1.84

117.17

8.4

9.1

4.53

4.20

e9/l

11.63

3168

22860

Noninflammatory disorders of female genital tract

13962

59876

1.36

117.01

8.1

8.5

3.96

4.00

e9/l

1.32

12304

52430

Conductive and sensorineural hearing loss

22866

140426

1.27

117.01

8.6

9.3

4.20

4.14

e9/l

2.74

20244

121988

Multiple myeloma and malignant plasma cell neoplasms

1252

7623

3.68

116.29

42.2

8.7

3.14

4.26

e9/l

73.93

1182

6596

Disorders of vitreous body and globe

13223

111147

1.38

115.97

9.3

4.02

4.12

e9/l

6.29

11652

96697

Disorders of vitreous body

12861

108327

1.39

115.89

9.3

4.00

4.12

e9/l

6.82

11323

94217

Malignant neoplasm of eye, brain and central nervous system, excluding all cancers (controls excluding all cancers)

1816

11761

2.47

115.85

17.7

6.7

4.08

4.25

e9/l

2.23

1604

10109

Other viral diseases, not elsewhere classified

5066

39394

1.68

115.65

13.5

9.0

4.04

4.01

e9/l

0.38

4536

34404

Transient ischemic attack

13750

97906

1.36

115.64

8.3

9.2

4.36

4.20

e9/l

8.73

12095

84636

Keratitis

9554

79802

1.44

115.41

9.6

9.1

4.13

4.10

e9/l

0.67

8517

69672

Fitting and adjustment of other devices

8777

67237

1.45

115.35

8.1

7.7

4.24

e9/l

0.09

8041

57373

Hypermobility syndrome

1595

10303

2.96

115.13

9.5

8.1

3.97

3.92

e9/l

0.51

1469

9090

Excessive attrition of teeth

11847

54417

1.41

115.05

9.2

8.3

3.93

4.03

e9/l

5.32

10390

48276

Acute appendicitis, no complications

16364

142207

1.31

115.03

8.6

9.2

4.38

4.02

e9/l

55.01

14474

125060

Speech and linguistic disorders, excluding more controls

2240

14161

2.16

114.99

13.5

7.4

4.00

3.86

e9/l

2.41

1927

12346

Mental and behavioural disorders due to use of other stimulants, including caffeine

887

4814

4.65

114.98

22.3

9.1

4.31

3.97

e9/l

3.71

773

4240

Disorders of calcium metabolism

1677

10950

2.83

114.48

15.2

8.7

4.47

4.04

e9/l

9.58

1536

9520

Injuries to the wrist and hand

30651

200651

1.22

114.28

8.7

9.1

4.09

e9/l

0.04

26950

175778

Sensorineural hearing loss

21419

132633

1.27

114.25

8.5

9.4

4.22

4.16

e9/l

3.05

18947

115110

Assault

3575

26487

1.85

114.06

9.7

9.4

4.31

4.00

e9/l

11.23

3109

23361

Social phobias

2353

16150

2.16

114.06

10.3

8.0

4.12

3.94

e9/l

3.50

2002

14278

Pyogenic arthritis

1755

11307

2.49

114.04

13.3

8.8

4.51

4.20

e9/l

5.19

1586

9762

Systemic sclerosis

785

4305

8.56

114.03

16.7

8.7

3.86

3.99

e9/l

1.11

759

3758

Haemorrhoids and perianal venous thrombosis

7556

61372

1.49

113.89

8.4

8.6

4.07

4.18

e9/l

3.83

6703

53002

Inflammatory disease of uterus

3961

30100

1.84

113.86

8.3

8.5

4.14

3.92

e9/l

8.34

3464

26558

Diseases of external ear

8917

74238

1.47

113.82

9.6

9.1

4.21

4.13

e9/l

2.24

7676

64781

Other and unspecified local infections of skin and subcutaneous tissue

2515

17772

2.21

113.75

13.3

8.9

4.36

4.09

e9/l

6.30

2250

15481

Other symptoms and signs involving the circulatory and respiratory systems

1763

11446

2.53

113.60

9.8

8.8

4.24

4.06

e9/l

2.60

1620

9893

Other local infections of skin and subcutaneous tissue

2665

19010

2.14

113.60

13.1

8.9

4.36

4.09

e9/l

6.38

2370

16551

Adenocarcinoma, papilloma adenocarcinoma and mucinous carcinomas of rectum

2458

17310

2.24

113.57

17.4

8.7

3.89

4.29

e9/l

15.60

2245

14990

Colon adenocarcinoma

2914

21053

2.04

113.49

16.2

8.6

3.94

4.31

e9/l

14.04

2645

18177

Volume depletion

2273

15443

2.16

113.38

14.8

8.2

4.88

4.22

e9/l

24.07

2082

13308

Follow-up examination after treatment for malignant neoplasms

2662

18679

2.03

113.21

12.0

8.4

3.96

4.22

e9/l

7.10

2420

15602

Chronic ulcer of skin, not elsewhere classified

1758

11551

2.65

113.07

13.5

8.6

5.09

4.24

e9/l

29.89

1638

9987

6941

49590

1.53

112.85

8.0

8.4

4.58

4.39

e9/l

6.97

6059

42477

Giant cell arteritis

1117

6692

4.13

112.61

14.8

8.7

5.02

4.18

e9/l

25.69

1026

5796

Stomatitis and related lesions

2277

15693

2.23

112.36

15.0

8.2

4.24

4.04

e9/l

1.47

2037

13675

Chronic iridocyclitis

1426

9040

3.18

112.17

14.4

8.9

3.99

4.06

e9/l

0.64

1339

7905

Transport accidents

13775

104771

1.33

111.89

8.3

9.0

4.07

4.03

e9/l

1.07

12143

92181

malignant neoplasm of male genital organs

9982

52711

1.41

111.77

9.4

9.1

4.35

4.50

e9/l

6.03

8748

45596

L02BX Other hormone antagonists and related agents

1329

8360

3.49

111.39

18.8

8.8

4.27

4.51

e9/l

2.95

1234

7245

Malignant neoplasm of other and unspecified female genital organs, excluding all cancers (controls excluding all cancers)

774

4176

6.64

111.11

29.1

6.5

3.55

4.08

e9/l

10.12

660

3523

Other inflammation of eyelid

3420

25566

1.93

110.90

11.1

9.0

3.96

4.07

e9/l

2.31

3001

22245

COPD, hospital admission 2, with asthma infections

7880

55034

1.48

110.61

11.8

8.7

5.39

4.26

e9/l

201.09

7067

47527

Extrapyramidal and movement disorders

9439

79214

1.44

110.30

9.3

9.0

4.20

e9/l

0.06

8246

68752

Need for immunization against other single viral diseases

649

3356

11.71

110.21

22.8

9.2

3.95

4.11

e9/l

0.80

605

2946

Benign neoplasm of mouth and pharynx

2642

18673

2.03

110.11

10.8

6.6

4.13

4.21

e9/l

1.15

2309

16074

Cholangitis (primary sclerosing, PSC), with reimbursement 202

603

3000

11.68

109.93

21.8

8.7

3.71

3.99

e9/l

2.87

581

2609

Spondylolisthesis/Spondylolysis

4825

37644

1.68

109.90

9.0

9.5

4.13

4.03

e9/l

2.46

4321

32600

Angina pectoris

16326

96210

1.32

109.80

8.5

9.6

4.43

4.12

e9/l

44.49

14371

83146

Disturbance of activity and attention

2847

20184

1.98

109.68

7.7

8.5

3.92

3.91

e9/l

0.16

2457

17695

Rare circulating lymphoid malignancy, excluding all cancers (controls excluding all cancers)

842

4551

4.60

109.64

41.4

6.5

3.05

4.26

e9/l

47.19

799

3902

Systemic sclerosis, icd10

776

4328

8.56

108.91

16.9

8.9

3.86

4.00

e9/l

1.25

752

3787

Emotional disorders starting during childhood or adolecense, excluding more controls

1366

8129

2.72

108.86

15.0

6.5

3.97

3.83

e9/l

1.64

1171

7091

Coxarthrosis, primary

15651

118654

1.32

108.38

8.3

9.2

4.23

4.20

e9/l

0.77

13669

102818

Urolithiasis

8289

68711

1.46

108.10

9.1

4.41

4.24

e9/l

7.21

7243

59914

Other inflammatory liver diseases

1796

12084

2.64

108.02

15.8

9.1

4.03

4.08

e9/l

0.33

1645

10577

Disorders of optic nerve and visual pathways

2569

18443

2.16

107.87

12.3

8.9

4.11

4.06

e9/l

0.56

2331

16127

Triptan medication for migraine, min. 3 purchases

16538

114251

1.31

107.54

7.5

8.9

3.90

3.94

e9/l

1.99

14751

100673

Primary gonarthrosis, bilateral

13453

101837

1.35

107.11

8.2

9.3

4.22

4.17

e9/l

1.72

11699

88320

Hyperkinetic disorders

3024

21773

1.93

107.06

8.0

8.9

3.93

3.91

e9/l

0.26

2608

19076

Hodgkin lymphoma, hilmo

872

4936

5.16

106.92

22.1

8.8

3.47

4.09

e9/l

15.00

802

4334

Melanocytic naevi of trunk

2897

20970

1.94

106.04

11.5

6.7

3.92

4.16

e9/l

7.34

2591

18179

Adenocarcinoma and papilloma adenocarcinoma of rectum

2350

16626

2.21

105.85

17.1

8.7

3.89

4.30

e9/l

14.99

2147

14395

Clear cell adenocarcinoma of kidney, excluding all cancers (controls excluding all cancers)

1127

6758

3.45

105.54

15.1

6.3

4.27

4.35

e9/l

0.60

997

5832

Other demyelinating diseases of the central nervous system

1119

6814

3.76

104.90

12.8

8.8

3.78

4.00

e9/l

3.69

1028

6011

Other diseases of pericardium

1199

7333

3.27

104.48

15.8

9.4

4.56

4.11

e9/l

7.73

1083

6349

Diseases of the myoneural junction and muscle

3025

22319

1.95

104.38

12.5

8.9

4.52

4.18

e9/l

9.41

2700

19378

COPD related to multimorbidity

9661

68420

1.41

104.35

10.3

8.8

5.26

4.25

e9/l

212.62

8585

59115

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2500

18011

2.17

104.19

15.7

8.8

4.40

4.15

e9/l

4.06

2299

15701

Hyperplasia of prostate

9426

44608

1.41

103.75

8.9

9.5

4.42

4.40

e9/l

0.27

8257

38638

Other degenerative diseases of the nervous system

7231

44528

1.47

103.49

9.3

9.2

4.33

4.16

e9/l

6.63

6354

38384

Injuries to the neck

6082

49089

1.55

103.37

8.3

9.0

4.13

4.07

e9/l

1.18

5342

43076

Other shoulder lesions

2517

17971

2.06

103.28

8.8

9.3

4.09

4.03

e9/l

0.75

2233

15643

Calculus of kidney and ureter

7679

63519

1.47

103.04

9.1

9.2

4.40

4.23

e9/l

7.01

6703

55445

Basal cell carcinoma, including avohilmo

14760

101190

1.32

102.91

9.1

9.0

4.19

4.26

e9/l

2.48

12746

87523

Acute pharyngitis

4055

30746

1.70

102.87

10.7

8.4

4.19

3.98

e9/l

6.48

3609

26805

Use of teriflunomide

386

1862

48.01

102.76

13.4

8.9

3.22

3.97

e9/l

20.96

371

1635

Osteonecrosis

1552

10314

2.87

101.95

19.9

8.9

4.23

4.10

e9/l

1.20

1382

8976

Nasal polyp

5014

39613

1.62

101.92

8.9

9.5

4.16

4.19

e9/l

0.43

4392

34601

TMD related operations

4459

34939

1.71

101.81

9.6

9.2

3.85

3.98

e9/l

3.90

4087

30694

Basal cell carcinoma

14356

99469

1.32

101.77

9.1

8.9

4.20

4.26

e9/l

2.32

12393

86025

Rash and other nonspecific skin eruption

2624

19104

2.07

101.04

12.8

8.9

4.03

4.06

e9/l

0.29

2327

16593

Other extrapyramidal and movement disorders in other diseases

5693

46001

1.60

100.92

8.8

9.1

4.17

4.15

e9/l

0.23

4986

40001

Other problems related to primary support group, including family circumstances

3249

23739

1.87

100.57

14.8

8.4

4.00

3.90

e9/l

1.48

2900

20761

Benign neoplasm: Descending colon

1564

10208

2.57

100.50

10.1

6.3

4.38

4.33

e9/l

0.35

1392

8763

Other and unspecified types of non-Hodgkin lymphoma, hilmo

1115

6822

3.50

100.23

23.8

8.9

3.72

4.22

e9/l

10.44

1029

5921

Temporal arteritis

994

5979

4.20

100.04

14.8

8.6

5.02

4.19

e9/l

22.60

915

5175

Other bursopathies

3412

25713

1.82

99.88

10.0

9.4

4.29

4.13

e9/l

2.99

3064

22279

Abnormalities of gait and mobility

2946

21890

1.97

99.87

9.0

8.9

4.54

4.21

e9/l

8.28

2511

18904

Superficial injury of lower leg

6625

54138

1.51

99.82

8.9

9.0

4.24

4.03

e9/l

10.31

5831

47319

Thyroiditis, ILD-related definition

3056

22695

1.89

99.50

9.2

8.2

3.99

e9/l

0.02

2728

19656

Use of interferon beta-1a

753

4195

6.07

99.45

15.1

8.8

3.36

3.98

e9/l

21.47

727

3707

Vascular disorders of the intestines

1619

10555

2.41

99.44

11.4

8.3

4.64

4.32

e9/l

5.44

1492

9086

Hyperparathyroidism

4578

35508

1.66

99.33

10.4

8.6

4.32

4.16

e9/l

3.76

4073

30641

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

4368

33102

1.70

98.88

10.3

9.4

4.06

3.99

e9/l

1.30

3869

28759

Malignant neoplasm of rectum

2339

16733

2.14

98.62

17.3

8.7

3.89

4.29

e9/l

14.38

2145

14491

Cardiomyopathies, Primary/intrinsic

3055

22529

1.84

98.43

11.1

9.2

4.52

4.17

e9/l

12.42

2693

19545

Umbilical hernia

6919

56909

1.49

98.41

9.1

9.3

4.40

4.18

e9/l

11.24

6103

49666

Insulin, combination of fast acting with intermediate-acting or long-acting

16995

138076

1.28

98.35

10.5

9.0

4.89

4.14

e9/l

252.18

15111

119993

Other disorders of patella

4691

36700

1.61

98.28

8.2

9.0

4.07

4.03

e9/l

0.73

4133

31881

Monoarthritis, not elsewhere classified

1205

7436

2.99

98.22

11.9

8.9

4.07

e9/l

0.01

1119

6473

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

1880

12620

2.17

97.82

23.7

6.0

4.53

4.42

e9/l

0.88

1693

10766

Fungal Sepsis

1014

6100

3.72

97.45

26.8

8.3

4.72

4.10

e9/l

12.23

959

5300

Benign neoplasm: Transverse colon

2490

18235

2.13

96.72

10.3

9.1

4.32

4.22

e9/l

1.26

2216

15826

Other general symptoms and signs

1415

9012

2.66

96.49

9.4

7.2

3.97

3.90

e9/l

0.50

1283

7737

Procreative management

9141

65040

1.41

96.39

11.4

9.8

3.72

3.96

e9/l

22.59

8062

57440

Abnormal results of function studies

2242

15997

2.16

96.31

11.6

8.8

4.18

4.05

e9/l

1.83

2031

13950

Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)

1285

8023

2.72

96.23

18.9

6.7

4.15

4.25

e9/l

0.86

1133

6937

Melanocytic naevi

7820

65359

1.46

96.19

10.4

8.9

3.90

4.07

e9/l

9.31

6935

57174

Ocular pain

2166

15438

2.23

96.10

10.5

8.9

4.02

e9/l

0.01

1959

13495

Disorders of vestibular function (Vertigo)

12299

106061

1.35

95.97

8.5

9.1

4.08

4.14

e9/l

2.24

10807

92275

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

3489

26641

1.80

95.85

11.8

9.4

4.09

4.21

e9/l

1.84

3134

23197

Radiculopathy

4234

32883

1.65

95.74

8.6

9.1

4.20

4.17

e9/l

0.43

3742

28330

Giant cell arteritis with polymyalgia rheumatica

994

6071

4.08

95.54

14.8

8.7

5.02

4.20

e9/l

22.04

915

5258

Other malignant neoplasms of skin (=non-melanoma skin cancer)

14000

96360

1.31

95.21

9.1

8.9

4.22

4.27

e9/l

1.15

12102

83233

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

1840

12646

2.33

95.15

15.2

8.7

4.40

4.03

e9/l

8.96

1653

11120

Stroke, excluding SAH

15733

102706

1.29

95.03

8.7

9.3

4.59

4.20

e9/l

59.88

13724

88841

Chronic hepatitis, not elsewhere classified

982

5957

3.97

94.97

17.3

8.9

3.69

4.03

e9/l

6.65

909

5223

Postmenopausal bleeding

7650

34869

1.48

94.50

9.4

9.7

4.01

3.99

e9/l

0.38

6565

30399

Malignant neoplasm of prostate

9585

50919

1.38

94.38

9.3

9.0

4.38

4.51

e9/l

4.88

8383

44012

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

883

4963

3.37

94.32

38.5

5.7

3.41

4.51

e9/l

5.46

823

4246

Respiratory insufficiency

1869

12512

2.09

94.07

12.0

7.1

5.39

4.09

e9/l

85.94

1694

10612

Injuries to the hip and thigh

12175

96187

1.33

93.75

9.6

8.8

4.46

4.21

e9/l

20.25

10583

83426

Chronic lymphocytic leukaemia

776

4390

4.85

93.74

29.9

8.8

3.40

4.33

e9/l

31.60

733

3819

Seborrhoeic keratosis

5532

44886

1.57

93.65

10.2

8.9

3.96

4.15

e9/l

8.96

4950

38808

Chronic laryngitis and laryngotracheitis

3620

27815

1.75

93.61

8.4

9.4

4.25

4.09

e9/l

3.25

3226

24284

Eating disorder

2532

18405

1.98

93.37

11.3

7.5

3.78

4.00

e9/l

6.10

2203

16197

Mental and behavioural disorders due to tobacco

2202

15818

2.18

93.18

11.3

9.2

4.89

4.06

e9/l

53.84

2019

13875

Hyperkalaemia

1320

8348

2.61

93.16

14.8

8.4

4.96

4.27

e9/l

16.15

1217

7240

Dental caries 2 and operation codes

22777

162845

1.23

93.12

9.7

9.0

3.91

4.03

e9/l

12.53

19741

143450

Disorder of lipoprotein metabolism, unspecified

3350

25432

1.78

92.84

9.1

8.7

4.54

4.21

e9/l

12.36

2822

22049

Peripheral artery disease

10959

75572

1.35

92.84

9.5

8.8

5.08

4.27

e9/l

155.57

9598

65207

Laparoscopic right hemicolectomy

1398

9322

2.96

92.66

12.5

9.0

4.00

4.24

e9/l

3.21

1214

8085

Alcohol abuse, main dg

4018

31279

1.68

92.41

10.2

9.3

4.54

4.09

e9/l

23.20

3526

27442

Use of pramipexole

5479

44540

1.57

92.03

8.4

9.1

4.22

4.16

e9/l

1.16

4829

38690

Open wound of lower leg

3731

28810

1.72

91.96

10.6

9.0

4.57

4.11

e9/l

23.15

3268

25142

Mental and behavioural disorders due to cannabinoids

889

5116

3.50

91.91

23.8

9.1

4.37

3.96

e9/l

4.94

785

4507

Malignant neoplasm of small intestine, excluding all cancers (controls excluding all cancers)

789

4424

4.10

91.90

18.4

6.5

3.70

4.30

e9/l

13.16

735

3813

Dental caries 2

23208

164384

1.23

91.85

9.7

9.0

3.91

4.03

e9/l

13.18

20067

144838

Benign neoplasm: Skin of eyelid, including canthus

3515

26759

1.72

91.78

9.1

6.4

4.19

4.22

e9/l

0.32

3045

22948

Other/unspecified synovitis and tenosynovitis

3095

23257

1.82

91.63

9.7

9.3

4.07

4.06

e9/l

0.05

2791

20254

Benign neoplasm: Stomach

2471

18204

2.08

91.61

10.6

9.1

4.11

4.12

e9/l

0.05

2203

15834

Smoking dependency

2202

15876

2.16

91.47

11.3

9.2

4.89

4.06

e9/l

53.70

2019

13919

Infections with a predominantly sexual mode of transmission

8513

71766

1.41

91.16

9.2

8.7

4.03

3.99

e9/l

0.99

7385

63346

Serous carcinoma of ovary, excluding all cancers (controls excluding all cancers)

912

5437

3.89

91.16

27.3

6.5

3.47

4.07

e9/l

15.21

825

4604

Emphysema

1698

11407

2.25

91.15

11.8

8.8

5.14

4.24

e9/l

32.93

1505

9820

Malignant neoplasm of head and neck

1999

14031

2.17

91.11

12.0

9.0

4.24

4.28

e9/l

0.35

1814

12171

Implicit fungal Sepsis

928

5559

3.82

91.06

26.1

8.3

4.65

4.08

e9/l

10.49

877

4843

Biological medicines for asthma

462

2289

31.42

90.94

11.1

8.8

4.30

3.99

e9/l

2.85

449

2015

Cardiomyopathy (excluding other)

3126

23431

1.78

90.75

11.1

9.2

4.52

4.16

e9/l

13.12

2753

20344

Herpesviral [herpes simplex] infections

3030

22893

1.86

90.37

14.0

8.8

4.05

4.04

e9/l

0.07

2739

20019

Neuromuscular dysfunction of bladder

2319

16768

2.04

90.14

11.3

8.8

4.29

4.13

e9/l

2.38

2060

14612

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

6290

51932

1.51

90.14

8.9

9.6

4.82

3.93

e9/l

170.03

5581

45457

Carcinoma in situ of skin

1745

11868

2.23

89.83

10.9

5.9

4.21

4.42

e9/l

2.71

1499

10097

Mental disorders, not otherwise specified

2257

16237

2.05

89.67

14.5

7.7

4.10

3.97

e9/l

2.24

1929

14305

Cirrhosis of liver, NAS

1280

8382

2.96

89.26

13.6

9.1

3.85

4.20

e9/l

4.49

1169

7310

Cardiomyopathy, other and unspecified

2001

14058

2.13

89.22

11.7

9.3

4.36

4.10

e9/l

5.43

1748

12203

Peripheral arterial reconstruction

3886

30168

1.66

88.83

9.1

8.4

5.31

4.40

e9/l

65.40

3435

25991

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

1401

8987

2.36

88.79

19.6

6.0

4.30

4.48

e9/l

1.70

1279

7678

Other disorders of bone

5303

42927

1.55

88.23

10.4

9.0

4.10

4.02

e9/l

1.16

4704

37538

Polyp of the female genital tract

9191

45309

1.40

88.14

8.8

9.3

3.88

4.00

e9/l

5.19

7978

39663

Other symptoms and signs involving the urinary system

2556

18792

1.92

88.12

11.4

8.9

4.21

e9/l

0.01

2333

16355

Stroke, including SAH

16723

109695

1.27

88.08

8.7

9.3

4.57

4.18

e9/l

66.07

14619

94951

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Neutrophils [#/volume] in Blood by Automated count

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS