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Respiratory conditions due to other external agents

EFO MESH Endpoint Browser PheWeb

J10_RESPCONDEXT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J70
  • Hospital discharge: ICD-9 — 508
  • Cause of death: ICD-10 — J70
  • Cause of death: ICD-9 — 508

2 out of 7 registries used, show all original rules.

848

4. Check minimum number of events

None

848

5. Include endpoints

None

848

6. Filter based on genotype QC (FinnGen only)

769

Control definitions (FinnGen only)

Control exclude
J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Morbositates respiratoriae ex aliis agentibus externis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5135 2989 2077
Only index persons 3638 2249 1389
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.06
Only index persons 0.07 0.08 0.05
Median age at first event (years)
Whole population 69.92 70.17 69.46
Only index persons 67.98 67.98 67.97

-FinnGen-

Key figures

All Female Male
Number of individuals 769 450 319
Unadjusted period prevalence (%) 0.15 0.16 0.15
Median age at first event (years) 66.97 64.19 70.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
786
Matched controls
7860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
+∞
318.0
283
*
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
+∞
307.7
293
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
14.0
212.1
224
218
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.6
130.0
224
393
H02AB06
ATC
prednisolone; systemic
7.4
124.1
643
2977
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.1
115.5
257
576
H02AB02
ATC
dexamethasone; systemic
6.0
112.4
259
598
TGC00
NOMESCO Finland
Bronchial lavation
12.3
109.8
116
109
A04AA02
ATC
granisetron; systemic, transdermal
7.1
98.6
171
297
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
95.2
232
556
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
9.0
94.5
127
165
GD1AD
NOMESCO Finland
Thorax CT examination
6.9
91.1
161
284
A03FA01
ATC
metoclopramide; systemic, rectal
4.3
87.6
354
1255
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.0
79.2
401
1640
J70.4
ICD-10 Finland
Drug-induced interstitial lung disorders, unspecified
+∞
75.2
71
*
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
19.0
74.7
60
34
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
11.2
74.4
82
81
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
9.8
74.0
90
102
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
72.8
582
3171
115
Kela drug reimbursment
Breast cancer
5.0
72.7
189
470
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.2
66.0
158
365
ZX070
NOMESCO Finland
Intensity modified radiotherapy
12.4
60.9
62
54
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.1
60.8
146
337
130
Kela drug reimbursment
Malignant tumour
4.5
58.3
166
439
J70.3
ICD-10 Finland
Chronic drug-induced interstitial lung disorders
+∞
58.0
55
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.1
57.0
107
197
WF049
NOMESCO Finland
Radiotherapy of metastasis
6.9
55.5
91
146
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.1
55.5
131
297
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
19.7
54.7
43
23
JN4AD
NOMESCO Finland
Body CT examination
3.8
51.2
191
611
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.2
51.2
94
169
J70.1
ICD-10 Finland
Chronic and other pulmonary manifestations due to radiation
+∞
50.6
48
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.1
49.6
115
256
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
7.0
49.5
80
126
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.7
49.2
55
55
L02BG04
ATC
letrozole; oral
4.4
49.1
138
359
JN4BD
NOMESCO Finland
Extensive body CT
3.9
49.1
172
526
A04AA55
ATC
palonosetron, combinations; systemic
6.4
48.9
86
148
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
48.4
397
2021
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
7.0
46.3
74
115
J01MA12
ATC
levofloxacin; systemic
3.1
45.8
254
1035
HA1AA
NOMESCO Finland
X-ray mammography
4.0
44.9
150
442
ZX080
NOMESCO Finland
Image guided radiotherapy
7.6
44.7
66
94
WZC30
NOMESCO Finland
Teaching
3.2
43.9
220
842
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
9.8
43.1
51
55
L03AA14
ATC
lipegfilgrastim; parenteral
8.8
42.4
55
67
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
4.4
41.1
114
292
L03AA13
ATC
pegfilgrastim; parenteral
4.9
39.9
95
215
WF003
NOMESCO Finland
Adjuvant radiotherapy
6.1
39.8
72
127
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.7
39.6
99
233
R50.9
ICD-10 Finland
Fever, unspecified
3.2
39.5
193
723
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
15.2
39.3
35
24
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
6.7
38.2
63
101
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
11.0
37.8
41
39
WF002
NOMESCO Finland
Radical radiotherapy
4.6
37.6
97
234
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
10.8
36.3
40
39
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
35.1
408
2361
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
4.4
35.0
95
238
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
34.1
166
616
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
4.9
33.7
79
176
J70.9
ICD-10 Finland
Respiratory conditions due to unspecified external agent
+∞
33.6
32
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.8
33.3
115
343
PJA12
NOMESCO Finland
Sentinel node biopsy
3.5
33.0
132
434
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
5.0
31.7
72
156
R06.0
ICD-10 Finland
Dyspnoea
2.4
31.0
319
1722
N02AA05
ATC
oxycodone; systemic
2.6
30.9
243
1157
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.0
29.6
91
250
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
29.2
251
1241
L01CA04
ATC
vinorelbine; systemic
10.7
29.1
32
31
A02BC02
ATC
pantoprazole; systemic
2.7
28.9
627
4642
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
28.5
203
916
B01AB10
ATC
tinzaparin; parenteral
3.0
28.4
145
549
WF004
NOMESCO Finland
Palliative radiotherapy
6.9
28.4
45
69
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
4.2
28.3
80
206
C01BD01
ATC
amiodarone; systemic
5.6
28.1
55
104
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
6.2
27.7
49
84
Z51.5
ICD-10 Finland
Palliative care
3.1
27.6
135
499
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
5.9
27.4
51
92
L02BG06
ATC
exemestane; oral
6.5
27.4
46
75
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
27.3
159
646
N02AA01
ATC
morphine; systemic, rectal
6.0
26.6
48
84
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
6.5
26.4
44
71
HAC20
NOMESCO Finland
Total mastectomy
4.2
25.9
72
183
L02BG03
ATC
anastrozole; oral
6.7
25.9
42
66
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.1
25.8
125
458
X76
ICPC
Malignant neoplasm breast female
6.0
25.8
47
83
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
10.3
25.7
29
29
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
10.0
25.1
29
30
JN4CD
NOMESCO Finland
Very extensive body CT
4.5
24.9
64
153
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
8.4
24.9
33
41
A04AA01
ATC
ondansetron; systemic, rectal
3.2
24.9
112
393
C03CA01
ATC
furosemide; systemic
2.2
24.7
362
2213
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
3.8
23.8
78
223
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.4
23.8
63
154
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
5.6
23.3
45
84
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
6.8
23.2
37
57
ZXE00
NOMESCO Finland
One hour or less
2.1
23.1
357
2213
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
4.2
23.0
63
158
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.2
21.8
60
151
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
7.1
21.8
33
48
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.7
21.7
71
203
XX1XN
NOMESCO Finland
Other isotope examination
9.2
21.3
26
29
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.9
21.3
48
103
HAB40
NOMESCO Finland
Wedge excision of mammary gland
3.3
21.2
84
272
WW500
NOMESCO Finland
Blood transfusion
4.0
21.1
62
164
A04AD12
ATC
aprepitant; systemic
5.4
21.0
42
81
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.2
20.9
36
60
TGD00
NOMESCO Finland
Needle biopsy of lung
20.7
20.5
30
15
J01MA14
ATC
moxifloxacin; systemic
2.8
20.2
110
428
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
7.5
20.0
29
40
NK6AN
NOMESCO Finland
Total body bone isotope imaging
4.5
19.2
48
112
C50.99
ICD-10 Finland
Breast, unspecified
4.2
19.1
52
130
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
18.2
247
1430
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
6.3
18.2
31
51
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
6.0
18.0
32
55
L03AA02
ATC
filgrastim; parenteral
4.3
17.9
47
114
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
17.9
122
530
XW000
NOMESCO Finland
Bone marrow biopsy
3.6
17.9
61
179
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
7.4
17.9
26
36
L04AA13
ATC
[U] leflunomide
5.1
17.7
38
78
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
7.6
17.5
25
34
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
4.7
17.2
40
88
M04AA01
ATC
allopurinol; systemic
2.3
17.2
149
722
B01AB05
ATC
enoxaparin; parenteral
1.9
16.9
301
1909
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
16.9
126
571
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
4.6
16.8
40
90
C50
ICD-10 Finland
Malignant neoplasm of breast
4.4
16.6
42
99
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.2
16.3
34
68
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
16.1
100
415
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
15.8
326
2156
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
13.3
15.8
27
21
A02BC01
ATC
omeprazole; systemic
1.9
15.7
257
1575
N05CF01
ATC
zopiclone; oral
1.9
15.7
307
1996
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
26.9
15.7
21
8
J70.8
ICD-10 Finland
Respiratory conditions due to other specified external agents
163.1
15.5
16
*
M05BX04
ATC
denosumab; parenteral
2.7
15.4
86
338
ZX120
NOMESCO Finland
Intravenous
2.5
15.3
105
456
N03AX16
ATC
[U] pregabalin
2.0
15.2
220
1291
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
4.4
15.2
39
93
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
15.1
116
531
L04AX01
ATC
azathioprine; systemic
3.9
15.0
45
121
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.4
14.9
38
90
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.6
14.9
50
145
L04AX03
ATC
methotrexate; systemic
2.5
14.8
100
431
L02BA01
ATC
tamoxifen; oral
3.2
14.7
59
192
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
5.8
14.7
27
48
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
14.6
67
236
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.8
14.4
76
290
ZXD05
NOMESCO Finland
Urgent procedure
1.9
14.4
254
1590
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
6.3
14.3
24
39
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
4.0
14.2
41
107
WX402
NOMESCO Finland
General anaesthesia
2.0
14.2
189
1075
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
4.8
14.1
32
69
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
13.0
14.0
24
19
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
13.0
14.0
24
19
JN6AD
NOMESCO Finland
CT of torso and neck
5.2
13.9
29
58
WX892
NOMESCO Finland
Monitored bed care
2.6
13.8
83
338
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.7
13.8
26
25
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
5.8
13.7
25
44
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
6.0
13.6
24
41
5088A
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESPIRATIONIS E PHARMACO]
+∞
13.6
13
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
6.2
13.5
23
38
N02AX02
ATC
tramadol; systemic, rectal
1.8
13.5
377
2698
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
5.1
13.4
28
56
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.8
13.4
69
259
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.0
13.3
61
215
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
13.3
404
2955
R06AE07
ATC
cetirizine; oral
1.8
13.1
337
2347
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
4.0
13.1
37
95
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
13.1
98
443
R04.2
ICD-10 Finland
Haemoptysis
3.5
12.9
46
139
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
12.9
166
930
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
12.8
61
220
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
5.0
12.7
27
55
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.4
12.5
31
72
L04AA06
ATC
mycophenolic acid; systemic
5.7
12.5
23
41
A41.9
ICD-10 Finland
Sepsis, unspecified
3.4
12.4
45
138
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
12.3
67
259
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
12.3
150
824
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.5
12.2
30
69
L01BA01
ATC
methotrexate; systemic
3.4
12.1
43
130
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
12.1
117
589
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
5.1
12.0
25
50
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
12.0
134
712
C07AB07
ATC
bisoprolol; oral
1.7
12.0
450
3452
R81
ICPC
Pneumonia
3.3
11.7
45
143
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
11.5
78
336
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.5
11.5
40
119
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.9
11.5
25
52
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.0
11.5
33
86
SPAT1263
SPAT
Sampling
1.7
11.4
332
2370
J96.1
ICD-10 Finland
Chronic respiratory failure
3.8
11.2
34
92
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
17.3
11.2
17
10
Z31.5
ICD-10 Finland
Genetic counselling
3.1
11.1
47
158
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
11.1
261
1756
J96.0
ICD-10 Finland
Acute respiratory failure
5.1
11.0
23
46
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
11.0
115
595
XG410
NOMESCO Finland
Flow-volume spirometry
3.1
10.9
47
160
WF099
NOMESCO Finland
Other radiotherapy
15.8
10.9
17
11
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
18.1
10.8
16
9
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
10.7
213
1362
J01MA02
ATC
ciprofloxacin; systemic
1.7
10.7
328
2361
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.2
10.7
100
496
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.3
10.6
27
64
R03AC02
ATC
salbutamol; inhalant
1.6
10.5
433
3357
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
9.7
10.3
20
21
ZX095
NOMESCO Finland
Combined chemoradiotherapy
9.7
10.3
20
21
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.4
10.2
36
108
J01CA04
ATC
amoxicillin; systemic
1.8
10.2
617
5269
A10AC01
ATC
insulin (human); parenteral
2.4
10.1
75
337
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
8.6
10.1
21
25
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
11.5
10.1
18
16
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
10.2
10.1
19
19
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
10.0
111
586
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.1
10.0
27
67
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
3.4
10.0
35
105
R84
ICPC
Malignant neoplasm bronchus/lung
17.0
9.9
15
9
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
4.3
9.9
25
59
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
9.9
51
192
M01CB01
ATC
sodium aurothiomalate; parenteral
5.2
9.9
20
39
A02BC05
ATC
esomeprazole; systemic
1.6
9.9
330
2416
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
10.8
9.8
18
17
R05
ICD-10 Finland
Cough
1.8
9.8
183
1147
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
13.6
9.7
16
12
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.3
9.7
36
112
I50.0
ICD-10 Finland
Congestive heart failure
2.2
9.7
90
445
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
10.2
9.6
18
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
9.5
168
1035
5088X
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESP CAUSA EXT ALIA DEFINITA]
+∞
9.4
9
*
ZX050
NOMESCO Finland
Stereotactic radiotherapy
8.2
9.4
20
25
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
22.0
9.4
13
6
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.7
9.3
29
80
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
8.8
9.3
19
22
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
3.9
9.3
27
71
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
3.8
9.1
27
72
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.4
9.1
65
287
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
11.6
9.1
16
14
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
5.0
8.9
19
39
M05BA04
ATC
alendronic acid; oral
2.0
8.8
97
510
J01DB01
ATC
cefalexin; oral
1.7
8.8
627
5455
NHQ40
NOMESCO Finland
Amputation of toe
4.2
8.8
23
56
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
50.6
8.7
10
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
7.8
8.7
19
25
I47.2
ICD-10 Finland
Ventricular tachycardia
3.7
8.6
27
75
A06AD11
ATC
lactulose; oral
1.8
8.6
144
870
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.7
8.5
45
172
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
20.3
8.5
12
6
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
20.3
8.5
12
6
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.5
114
643
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
4.4
8.4
21
49
I50.1
ICD-10 Finland
Left ventricular failure
2.4
8.4
58
252
L04AD01
ATC
ciclosporin; systemic
4.5
8.4
20
45
H02AB09
ATC
hydrocortisone; systemic
3.8
8.4
25
67
P01BA02
ATC
hydroxychloroquine; oral
2.1
8.3
77
379
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
8.7
8.3
17
20
ED1AA
NOMESCO Finland
Mandibular X-ray examination
10.9
8.3
15
14
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
9.6
8.3
16
17
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
8.3
126
740
J94.8
ICD-10 Finland
Other specified pleural conditions
4.3
8.2
21
50
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
14.7
8.2
13
9
WX730
NOMESCO Finland
Conventional respirator
4.8
8.1
18
38
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
3.8
8.1
24
64
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
4.1
8.1
22
55
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
11.9
8.1
14
12
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
8.1
326
2462
D70.89
ICD-10 Finland
Neutropenic splenomegaly
6.7
7.9
19
29
R03AK08
ATC
formoterol and beclometasone; inhalant
2.6
7.9
44
173
R03BB04
ATC
tiotropium bromide; inhalant
1.9
7.9
102
568
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.2
7.8
20
48
JN5KR
NOMESCO Finland
Very extensive PET-CT of upper body metabolism (eyebrows to thighs)
15.2
7.7
12
8
D64.9
ICD-10 Finland
Anaemia, unspecified
1.9
7.7
104
587
B01AA03
ATC
warfarin; systemic
1.7
7.7
178
1175
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.7
7.7
40
152
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.7
7.6
24
67
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
7.6
164
1062
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
8.1
7.6
16
20
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
8.1
7.6
16
20
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
6.8
7.6
18
27
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
18.6
7.6
11
6
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
25.3
7.6
10
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
3.5
7.6
26
77
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.3
7.6
19
31
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.5
210
1452
PD5BD
NOMESCO Finland
Extensive CT of aorta
4.0
7.5
21
54
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
7.5
61
286
PWG00
NOMESCO Finland
Reoperation on peripheral vessels for thrombosis or embolism
80.8
7.4
8
*
A10AB05
ATC
insulin aspart; parenteral
2.2
7.4
65
314
B01AB04
ATC
dalteparin; parenteral
2.4
7.3
48
204
L01CB01
ATC
etoposide; systemic
9.5
7.3
14
15
R02
ICPC
Shortness of breath/dyspnoea
1.8
7.3
125
759
WPA44
NOMESCO Finland
Nursing home for palliative care
15.9
7.2
11
7
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.6
7.2
23
65
1515, ,
Kela drug reimbursment
30.3
7.2
9
*
3030
Kela drug reimbursment
Abemaciclib
30.3
7.2
9
*
SPAT1262
SPAT
Handing over of treatment supplies
1.7
7.1
142
900
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
4.1
7.1
19
47
TQW20
NOMESCO Finland
Tatoe
5.7
7.1
19
34
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.3
7.0
26
81
A06AH03
ATC
naloxegol; oral
3.9
7.0
20
52
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
8.4
6.8
14
17
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
11.1
6.8
12
11
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
9.4
6.8
13
14
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
6.8
63
311
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
6.7
55
259
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.6
6.6
21
59
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
6.6
320
2484
WW200
NOMESCO Finland
Immunization
3.3
6.6
24
74
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.6
266
1989
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
12.4
6.6
11
9
SPAT1255
SPAT
Intravenous administration of medicine
2.1
6.6
59
288
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
10.1
6.5
12
12
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
6.5
36
141
N05BA04
ATC
oxazepam; oral
1.6
6.5
206
1461
L04AB01
ATC
etanercept; parenteral
5.4
6.5
18
34
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
3.4
6.5
23
70
XX9TE
NOMESCO Finland
Compementary ultrasound examination
7.5
6.4
14
19
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.4
88
499
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.5
6.4
40
167
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.0
6.4
28
97
L88
ICPC
Rheumatoid/seropositive arthritis
2.5
6.4
39
161
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.4
334
2629
TQB05
NOMESCO Finland
Puncture of skin of trunk
6.6
6.4
15
23
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
11.1
6.3
11
10
I70.0
ICD-10 Finland
Atherosclerosis of aorta
9.4
6.3
12
13
GAA31
NOMESCO Finland
Thoracoscopy
18.2
6.3
9
5
L01EB03
ATC
afatinib; oral
+∞
6.3
6
*
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
+∞
6.3
6
*
Z3231
NOMESCO Finland
Registered nurse
1.5
6.2
210
1508
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.7
6.2
19
52
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
6.2
196
1387
J01AA02
ATC
doxycycline; systemic
1.5
6.2
602
5334
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
3.6
6.2
20
57
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
6.3
6.2
15
24
J01FF01
ATC
clindamycin; systemic
1.5
6.2
207
1485
A07AA09
ATC
vancomycin; oral
4.2
6.1
16
39
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.3
6.1
43
190
L02BA03
ATC
fulvestrant; parenteral
6.8
6.1
14
21
ZY010
NOMESCO Finland
Hospital outpatient
2.6
6.0
35
141
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
6.1
6.0
15
25
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
6.0
40
172

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
105
10.28
81.20
2.3
2.8
—
—
—
0
0
444
2138
3.47
64.57
7.0
4.3
—
—
—
0
0
212
652
4.08
61.04
3.2
2.0
352.22
382.96
nmol/l
1.34
205
599
307
1255
3.37
56.86
5.7
3.1
0.80
0.82
mmol/l
1.28
299
1174
195
613
3.90
53.85
7.2
3.5
1.23
1.23
mmol/l
0.10
185
533
90
150
6.65
52.87
4.3
3.7
—
—
—
0
0
451
2390
3.08
52.18
9.8
5.8
—
—
—
0
0
38
17
23.44
52.07
1.7
1.6
28.87
30.18
%
0.09
38
17
79
117
7.39
51.79
3.2
2.7
4.40
4.47
e9/l
0.07
79
117
84
135
6.85
51.06
5.2
4.4
2.62
2.66
mmol/l
0.04
67
92
199
658
3.71
50.77
1.6
1.4
—
—
—
0
0
133
333
4.60
49.69
2.2
1.9
3.09
2.47
ug/l
0.13
123
294
608
3940
3.40
47.16
20.8
9.4
4.39
4.12
e9/l
2.10
579
3421
433
2348
2.88
46.23
7.3
3.9
7.40
7.40
ph
2.53
354
1710
535
3255
3.02
45.79
11.1
6.1
9.06
8.99
%
0.19
521
3036
561
3514
3.08
45.30
10.5
5.8
0.64
0.59
e9/l
3.35
525
2973
561
3528
3.06
44.70
10.5
5.8
0.04
0.04
e9/l
0.09
525
2991
532
3254
2.96
44.57
11.0
6.0
2.43
2.86
%
4.28
516
3030
536
3296
2.97
44.38
11.2
6.1
22.66
26.81
%
14.75
523
3107
530
3252
2.93
43.82
11.2
6.1
0.61
0.69
%
2.18
514
3022
44
38
12.21
43.27
1.7
1.7
40.70
39.86
%
0.09
44
38
166
541
3.62
42.71
4.7
4.2
—
—
—
0
0
561
3575
2.99
42.70
11.0
5.9
1.57
1.90
e9/l
7.47
529
3107
565
3637
2.97
41.75
11.0
6.0
0.17
0.19
e9/l
1.74
530
3137
81
154
5.75
41.43
3.6
2.6
61.75
59.66
%
0.58
81
154
60
87
7.38
39.93
1.7
1.5
—
—
—
0
0
60
87
7.38
39.93
1.7
1.5
—
—
—
0
0
60
87
7.38
39.93
1.7
1.5
—
—
—
0
0
60
87
7.38
39.93
1.7
1.5
—
—
—
0
0
518
3238
2.76
39.56
10.7
5.9
61.66
57.88
%
9.37
509
3073
183
664
3.29
39.50
5.0
4.4
1.20
0.96
%
0.62
104
217
300
1432
2.77
39.50
8.0
4.8
—
—
—
0
0
174
634
3.24
37.11
4.9
4.3
1.11
0.60
%
1.83
94
200
573
3840
2.82
36.90
13.3
6.4
9.30
11.52
umol/l
8.40
557
3664
63
111
6.08
34.78
2.1
2.6
—
—
—
0
0
169
631
3.14
34.39
5.0
4.5
0.13
0.13
%
0.02
90
185
53
84
6.69
32.43
2.6
2.1
89.18
89.43
%
0.12
53
84
166
640
3.02
31.75
5.2
4.7
0.06
0.17
%
0.86
87
169
550
3831
2.45
28.96
11.3
6.8
1.21
1.21
mmol/l
0.06
425
3302
514
3476
2.38
28.95
10.0
6.1
1.21
1.21
mmol/l
0.41
498
3184
274
1457
2.35
26.74
3.2
3.1
491.70
521.03
mosm/kgh2o
1.69
239
1276
72
188
4.12
24.99
2.8
2.1
125.46
127.09
g/l
0.21
56
149
218
1092
2.38
24.01
2.1
2.0
—
—
—
0
0
410
2663
2.13
23.57
5.2
3.6
2.35
2.36
mmol/l
0.66
388
2389
449
3023
2.13
23.43
27.9
11.9
0.00
0.00
e9/l
0.46
401
2468
188
899
2.43
22.85
8.2
7.2
1.61
1.03
mmol/l
1.10
165
746
189
906
2.43
22.84
8.3
7.2
7.42
7.42
ph
0.50
125
531
501
3556
2.13
22.26
22.4
16.0
1.28
1.29
inr
0.07
446
2946
73
211
3.71
21.94
1.5
1.4
—
—
—
0
0
186
911
2.36
21.27
8.4
7.2
5.03
5.11
kpa
0.35
180
886
186
912
2.36
21.21
8.4
7.2
10.44
11.84
kpa
4.69
181
889
356
2267
2.04
20.78
3.9
2.5
55.16
98.65
u/l
0.66
334
2091
39
71
5.73
20.73
1.7
1.5
30.21
28.82
ng/l
0.07
39
71
287
1697
2.09
20.44
3.3
2.7
5.86
5.75
e6/l
0.04
262
1551
474
3360
2.03
20.30
7.3
4.8
33.24
35.18
g/l
11.54
447
3151
315
1942
2.04
19.90
3.9
3.4
—
0.00
estimate
—
0
8
127
543
2.60
19.35
4.9
2.8
10.00
10.77
g/l
0.88
118
495
162
788
2.33
18.60
1.7
1.7
—
—
—
0
0
324
2071
1.96
18.03
3.9
3.5
0.36
0.49
e6/l
0.81
274
1539
192
1014
2.18
18.02
6.1
4.9
1.08
1.03
mmol/l
1.24
173
926
37
76
5.06
17.25
1.3
1.1
—
—
—
0
0
34
65
5.42
17.15
1.1
1.1
—
—
—
0
0
255
1526
1.99
16.97
2.5
1.6
1.50
1.35
mg/l
0.34
209
1205
213
1210
2.04
16.30
2.8
2.5
2.30
2.29
g/l
0.13
195
1115
75
266
3.01
16.21
1.3
1.2
—
—
—
0
0
99
410
2.62
15.98
1.3
1.3
—
—
—
0
0
202
1138
2.04
15.75
2.9
2.5
19.59
21.56
%
1.44
183
1054
541
4230
1.89
15.02
9.1
4.9
6.70
6.72
mmol/l
0.09
524
4039
221
1306
1.96
14.95
3.0
2.5
11.16
12.23
umol/l
1.52
203
1212
368
2570
1.81
14.66
4.5
3.2
1290.93
1454.89
ng/l
0.53
342
2227
135
670
2.23
14.53
9.4
6.2
10.45
10.25
mmol/l
0.10
129
644
404
2910
1.80
14.44
6.1
4.1
41.91
67.54
ng/l
0.56
340
2228
347
2402
1.80
14.07
4.1
3.6
29.92
94.34
e6/l
1.50
296
1866
140
714
2.17
14.06
1.6
1.5
—
—
—
0
0
639
5335
2.06
13.95
20.1
8.3
80.76
80.05
u/l
0.17
633
5022
32
70
4.72
13.87
1.1
1.1
—
—
—
0
0
137
697
2.17
13.83
4.0
2.7
65.06
66.55
g/l
1.37
125
637
290
1910
1.82
13.82
5.0
3.7
0.16
0.05
estimate
0.31
152
619
37
93
4.13
13.49
1.3
1.6
—
—
—
0
0
98
437
2.42
13.49
2.8
1.6
1.25
1.48
g/l
0.34
90
395
167
926
2.02
13.39
1.5
1.3
180.47
515.36
titre
7.65
43
224
124
616
2.20
13.26
1.7
1.5
—
—
—
0
0
108
509
2.30
13.10
3.7
3.2
7.43
7.42
ph
0.42
102
428
41
114
3.74
13.02
1.9
2.3
30.71
32.09
pg
1.04
41
114
196
1167
1.91
12.70
2.6
1.9
30.52
29.36
s
1.82
187
1127
43
127
3.52
12.50
1.8
2.3
0.94
0.92
%
0.08
37
89
371
2701
1.71
12.00
4.9
4.2
57.49
117.77
e6/l
1.25
308
1945
40
116
3.58
11.95
1.3
1.5
33.89
31.73
g/l
0.54
35
106
113
579
2.11
11.09
1.9
1.5
—
—
—
0
0
305
2141
1.69
11.05
12.3
6.2
—
—
—
0
0
162
951
1.89
10.79
3.6
2.6
1.76
1.84
%
0.42
146
854
82
378
2.31
10.43
3.2
3.1
4.17
4.40
pmol/l
1.08
72
326
118
632
2.02
10.25
4.5
3.1
284.15
223.74
ng/l
0.57
110
589
32
89
3.71
10.18
1.3
1.3
—
—
—
0
0
363
2721
1.62
9.85
5.6
4.3
0.00
0.04
estimate
2.65
147
645
147
862
1.87
9.76
3.5
4.1
6.46
27.68
ug/l
1.46
123
719
307
2221
1.63
9.54
6.5
3.2
33.39
31.66
u/l
0.24
296
2089
292
2096
1.63
9.32
5.8
4.4
0.00
0.00
estimate
0.50
163
727
86
427
2.14
9.12
1.3
1.2
458.15
267.81
u/ml
0.45
79
386
551
4628
1.64
8.93
6.9
5.2
1930.14
2386.35
e6/l
0.11
14
77
107
585
1.96
8.73
3.7
2.3
—
—
—
0
0
115
647
1.91
8.62
10.1
8.2
—
—
—
0
0
130
761
1.85
8.62
3.9
3.3
2.48
1.86
mmol/l
1.28
116
649
460
3719
1.57
8.59
5.5
4.3
0.00
0.41
estimate
0.52
166
762
452
3644
1.57
8.52
5.5
4.3
0.00
0.00
estimate
-0.00
170
791
455
3682
1.56
8.37
5.6
4.3
7.88
4.30
estimate
0.17
176
814
147
902
1.77
8.33
1.7
1.4
—
—
—
0
0
127
751
1.82
8.13
3.1
2.7
69.52
69.85
e9/l
0.04
104
560
28
85
3.38
7.86
1.4
1.3
—
—
—
0
0
356
2757
1.53
7.80
2.4
2.2
—
—
—
0
0
31
101
3.15
7.78
1.4
1.3
115.67
165.14
au/ml
—
6
31
141
871
1.75
7.78
4.4
3.2
4.65
4.70
e9/l
0.03
128
736
33
112
3.03
7.74
1.4
1.3
—
—
—
0
0
19
44
4.40
7.71
2.9
3.1
41.58
39.70
%
0.15
12
28
30
99
3.11
7.38
1.4
1.3
1409.00
1511.38
e6/l
0.08
17
66
130
796
1.76
7.38
3.8
3.4
7.39
7.38
ph
1.05
80
448
31
107
2.98
7.08
1.1
1.1
—
—
—
0
0
27
86
3.22
7.04
1.9
1.3
—
—
—
0
0
67
335
2.09
6.99
1.4
1.3
—
—
—
0
0
402
3242
1.49
6.98
3.4
2.8
—
—
estimate
—
0
0
34
125
2.80
6.94
1.8
1.6
—
—
—
0
0
316
2442
1.49
6.70
4.6
3.4
—
—
—
0
0
228
1645
1.54
6.69
4.0
3.0
2.49
2.46
mmol/l
3.47
210
1476
48
214
2.32
6.63
5.6
5.5
1.41
1.35
mmol/l
0.23
43
191
56
270
2.16
6.42
4.8
3.5
80.33
74.44
mg/l
0.07
36
233
56
271
2.15
6.36
4.8
3.5
56.49
58.17
mg/l
0.03
36
235
29
103
2.89
6.32
1.2
1.2
257.05
315.42
u/ml
0.37
19
55
26
87
3.06
6.28
1.3
1.3
38750.08
111897.44
e6/l
0.47
13
48
52
247
2.18
6.19
4.8
3.2
4.53
4.20
ratio
0.05
22
141
262
1984
1.48
6.00
2.9
2.3
3.17
2.99
mg/l
0.57
242
1680
544
4734
1.48
5.99
7.0
4.9
—
2.26
—
0
10
19
54
3.58
5.91
1.3
1.3
—
—
—
0
0
28
104
2.75
5.65
1.1
1.0
—
—
—
0
0
18
51
3.59
5.63
2.7
2.9
14.91
16.26
%
0.90
18
51
43
197
2.25
5.61
2.8
2.8
1.64
1.64
mg/l
0.01
36
171
116
743
1.66
5.54
2.1
2.1
0.21
0.20
g/l
0.24
109
691
216
1597
1.49
5.49
2.0
1.8
485.88
14023432.55
pmol/l
1.06
164
1305
16
33
4.93
5.45
1.0
1.0
—
—
—
0
0
35
149
2.41
5.39
1.3
1.2
—
—
—
0
0
35
151
2.38
5.24
1.2
1.2
—
—
—
0
0
229
1733
1.45
5.12
1.5
1.4
—
—
—
0
0
598
6468
0.68
4.66
5.9
6.4
2.65
2.62
mmol/l
0.33
528
5916
26
104
2.55
4.58
1.7
1.5
311.46
294.56
mu/l
0.13
26
94
120
812
1.56
4.56
1.8
1.7
—
—
—
0
0
34
155
2.25
4.53
1.6
1.3
55.89
61.90
mmol/l
0.41
28
130
386
3252
1.37
4.48
3.1
2.4
81.33
79.69
nmol/l
0.61
357
2875
38
183
2.13
4.43
1.8
1.6
—
—
—
0
0
349
2913
1.36
4.22
4.5
3.8
6.34
6.26
ph
0.64
196
1600
584
6314
0.71
4.14
5.1
5.4
1.49
1.50
mmol/l
0.21
515
5761
116
800
1.53
4.05
3.8
2.7
8.63
7.66
umol/l
0.18
92
710
13
31
4.25
4.02
1.1
1.0
—
—
—
0
0
286
2331
1.36
3.97
2.5
2.2
120.66
200.19
u/l
3.51
276
2211
589
6349
0.71
3.97
5.2
5.5
4.61
4.57
mmol/l
0.34
520
5843
366
3099
1.34
3.94
3.8
3.0
203.80
128.23
ug/l
2.52
342
2844
131
938
1.48
3.82
1.4
1.3
—
—
—
0
0
98
661
1.55
3.78
3.2
2.4
37.81
35.56
u/l
0.18
86
550
16
55
2.95
3.75
1.6
1.3
0.42
0.38
g/l
0.30
11
42
16
55
2.95
3.75
1.6
1.3
2.10
2.94
g/l
1.18
11
43
16
55
2.95
3.75
1.6
1.3
4.96
6.63
g/l
2.90
11
43
560
6070
0.73
3.73
4.4
4.5
1.33
1.26
mmol/l
1.44
487
5475
16
57
2.84
3.54
1.6
1.3
—
—
—
0
0
228
1823
1.35
3.51
3.9
2.8
356.24
345.31
umol/l
0.66
202
1580
17
63
2.74
3.51
2.1
1.7
2.33
1.94
u/field
—
9
32
7
10
7.05
3.37
1.3
1.3
—
—
—
0
0
27
128
2.15
3.33
1.2
1.3
157.07
254.54
miu/ml
—
8
57
60
374
1.65
3.23
2.2
1.8
1.58
1.54
g/l
0.13
48
337
14
50
2.83
3.10
1.2
1.2
3.96
0.80
u/ml
—
9
29
35
189
1.89
3.06
3.9
3.1
4.10
2.12
index
0.84
20
101
7
12
5.87
3.02
1.1
1.8
—
—
—
0
0
464
4150
1.29
3.02
4.5
3.2
69.04
51.23
u/l
1.84
429
3843
12
37
3.28
2.94
5.6
3.2
0.83
0.84
index
0.01
12
37
8
17
4.74
2.92
1.3
1.2
—
—
—
0
0
22
102
2.19
2.89
1.7
1.7
0.81
0.83
g/l
0.02
16
84
238
2835
0.77
2.85
2.1
2.0
1.45
1.32
mmol/l
1.65
170
2349
8
18
4.48
2.80
1.3
1.4
—
—
—
0
0
15
60
2.53
2.71
1.5
1.4
0.41
0.26
nmol/l
—
5
44
185
1485
1.32
2.71
6.0
4.2
363.96
337.61
ng/l
0.04
161
1222
18
80
2.28
2.62
5.1
4.3
—
—
—
0
0
10
31
3.25
2.52
1.2
1.5
2.70
3.27
%
—
10
25
173
1390
1.31
2.51
1.9
1.8
1264.16
1203.37
nmol/l
0.30
116
1031
39
233
1.71
2.50
1.3
1.5
262.12
283.94
ug/g
0.26
25
144
584
6198
0.78
2.45
7.1
7.0
40.77
39.79
mmol/mol
1.90
521
5736
87
632
1.42
2.38
3.6
3.5
91.55
83.97
ng/l
0.35
70
542
165
1327
1.31
2.37
2.1
1.5
2.68
2.57
g/l
0.24
115
752
32
186
1.75
2.27
1.3
1.2
120.00
104.29
titre
—
9
21
17
79
2.18
2.26
3.6
1.7
25.63
5260.69
u/l
—
7
21
9
29
3.13
2.23
2.2
1.7
—
—
—
0
0
16
73
2.22
2.22
1.3
1.2
—
—
—
0
0
268
2308
1.24
2.19
3.0
2.5
—
—
—
0
0
9
30
3.02
2.15
1.0
1.0
—
—
—
0
0
9
30
3.02
2.15
1.0
1.0
—
—
—
0
0
9
30
3.02
2.15
1.0
1.0
—
—
—
0
0
44
284
1.58
2.13
1.7
1.6
7.33
7.64
iu/ml
—
9
75
103
787
1.36
2.10
2.3
2.1
201.92
133.50
ug/g
0.90
78
607
252
2166
1.24
2.08
3.9
3.5
—
—
—
0
0
603
6341
0.79
2.05
5.9
5.6
6.02
6.01
mmol/l
0.11
534
5740
9
32
2.83
2.00
3.3
3.0
1144.11
1267.59
u/ml
—
9
32
13
57
2.30
1.98
1.9
2.4
898.20
594.47
ml
—
5
34
13
57
2.30
1.98
2.2
2.5
—
—
—
0
0
5
11
4.57
1.94
1.0
1.0
—
—
—
0
0
5
11
4.57
1.94
1.2
1.2
—
—
—
0
0
18
332
0.53
1.94
1.4
1.4
—
—
—
0
0
8
27
2.98
1.94
1.0
1.4
—
—
—
0
0
13
59
2.22
1.85
2.0
1.4
42.71
34.97
%
—
8
36
144
1179
1.27
1.80
1.3
1.3
41.36
11.79
u/ml
1.36
43
422
13
60
2.19
1.78
1.2
1.2
77.08
102.33
pmol/l
1.38
13
60
11
47
2.36
1.78
1.2
1.2
—
—
—
0
0
21
117
1.82
1.76
1.0
1.1
—
—
—
0
0
125
1010
1.28
1.74
1.3
1.3
—
—
—
0
0
5
13
3.86
1.71
3.6
2.9
—
—
—
0
0
29
180
1.63
1.68
1.3
1.8
1.53
40.22
iu/l
—
7
66
12
55
2.20
1.68
1.5
1.2
—
—
—
0
0
102
817
1.29
1.53
1.4
1.3
—
—
—
0
0
6
21
2.87
1.51
3.0
2.0
0.61
0.61
mmol/l
—
6
21
14
72
1.96
1.49
1.0
1.1
—
—
—
0
0
10
45
2.24
1.47
1.1
1.1
—
—
—
0
0
9
38
2.38
1.46
1.0
1.1
—
9.13
—
0
10
55
733
0.73
1.44
5.3
4.1
7.39
7.37
ph
2.38
49
515
546
5163
1.19
1.44
5.9
4.5
15.20
15.00
pmol/l
0.87
495
4673
5
16
3.14
1.44
1.4
1.7
2.40
9.43
%
—
5
7
96
1182
0.79
1.42
3.0
3.4
0.85
0.80
ug/l
0.15
67
806
666
6420
1.24
1.42
40.7
17.6
27.02
25.23
mg/l
0.77
640
5388
24
150
1.62
1.39
1.4
1.2
70.25
31.25
u/l
0.52
19
129
5
17
2.95
1.36
6.8
1.5
0.00
0.00
estimate
—
5
17
29
193
1.52
1.31
1.2
1.2
—
—
—
0
0
260
2331
1.17
1.30
1.8
1.8
19.85
20.65
nmol/l
0.37
220
1945
8
34
2.37
1.29
2.3
1.8
43.86
51.66
ug/l
—
8
34
150
1282
1.21
1.28
1.4
1.3
35.04
34.27
iu/ml
0.03
59
398
11
55
2.01
1.27
3.2
2.8
8.15
7.76
mmol/l
0.14
11
55
178
2032
0.84
1.26
5.4
6.1
3.35
3.12
ug/l
0.08
153
1806
16
92
1.75
1.25
1.1
1.1
1.55
1.58
g/l
0.06
16
82
10
49
2.05
1.22
1.4
1.2
—
—
—
0
0
669
6878
0.82
1.20
55.8
27.0
4.18
4.41
e12/l
22.98
662
6704
8
38
2.12
1.18
1.3
1.2
—
—
—
0
0
669
6876
0.82
1.18
56.1
27.1
255.88
246.65
e9/l
2.76
662
6729
29
198
1.48
1.18
1.3
1.2
—
760.00
titre
—
0
6
6
128
0.46
1.17
1.0
1.2
1.51
1.59
g/l
—
6
128
10
50
2.01
1.17
1.5
2.6
38.30
27.74
mg/l
—
10
39
26
175
1.50
1.14
3.9
3.2
237.19
2156.54
u/ml
0.73
21
166
8
40
2.01
1.12
1.6
1.7
11.96
13.88
umol/l
—
8
35
670
6879
0.82
1.12
55.8
27.1
7.23
6.75
e9/l
5.81
663
6707
10
51
1.97
1.11
2.8
2.4
—
44.91
—
0
7
42
313
1.36
1.09
3.8
3.6
263.41
1408.42
u/ml
1.10
34
271
7
32
2.20
1.08
2.6
3.5
—
—
—
0
0
15
89
1.70
1.08
1.8
1.6
46.89
63.44
%
—
9
59
230
2539
0.87
1.05
3.4
3.4
38.95
45.06
mg/l
0.26
135
1578
47
359
1.33
1.05
4.1
3.3
—
—
—
0
0
149
1300
1.18
1.03
3.8
3.2
0.75
1.10
e6/l
1.23
86
701
9
48
1.88
1.00
1.2
1.6
—
—
—
0
0
25
354
0.70
0.99
2.7
2.1
—
—
—
0
0
9
52
1.74
0.92
1.2
1.1
—
—
—
0
0
6
29
2.08
0.89
2.7
3.7
—
—
—
0
0
79
660
1.22
0.89
1.5
1.6
—
—
—
0
0
10
56
1.80
0.88
1.3
1.4
39.49
34.41
u/l
—
10
46
10
57
1.76
0.84
3.2
1.8
—
—
—
0
0
13
81
1.62
0.81
3.3
2.3
0.28
1.24
g/24h
—
8
46
0
26
0.00
0.78
0.0
1.2
—
139.15
—
0
20
12
74
1.63
0.78
2.0
2.4
—
—
—
0
0
10
59
1.70
0.76
1.1
1.0
0.45
0.33
u/ml
—
5
30
135
1201
1.15
0.75
3.9
3.3
2.11
2.41
e6/l
0.21
73
597
45
361
1.26
0.75
1.3
1.3
—
—
—
0
0
239
2579
0.89
0.74
3.3
3.3
6.20
7.05
mmol/l
3.14
179
2153
24
321
0.74
0.72
1.7
1.8
3.34
3.42
mmol/l
0.12
18
247
9
56
1.61
0.72
1.2
1.1
—
—
—
0
0
39
309
1.28
0.72
2.2
2.9
—
—
—
0
0
13
194
0.66
0.71
1.2
1.1
—
—
—
0
0
48
391
1.24
0.71
2.5
2.5
—
—
—
0
0
9
59
1.53
0.68
1.3
1.1
—
—
—
0
0
20
144
1.40
0.68
2.1
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
7.58
—
0
21
243
2593
0.91
0.60
4.3
4.1
7.49
7.98
mg/mmol
0.08
128
1563
14
97
1.45
0.59
1.1
1.1
—
—
—
0
0
48
401
1.21
0.59
2.3
2.4
9.48
12.88
nmol/l
2.75
40
346
10
65
1.55
0.55
1.9
2.0
—
—
—
0
0
48
405
1.20
0.54
1.4
1.2
120.84
145.08
u/ml
0.17
11
154
11
74
1.49
0.53
1.0
1.6
10.56
9.89
%
0.14
11
74
188
1753
1.10
0.49
2.9
2.5
—
—
—
0
0
16
212
0.75
0.49
1.5
1.8
—
—
—
0
0
7
45
1.56
0.49
1.4
1.3
—
—
—
0
0
16
119
1.35
0.48
1.2
1.2
—
—
—
0
0
30
365
0.81
0.48
3.0
2.2
0.00
0.01
estimate
0.50
16
111
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
64
713
0.89
0.37
2.8
2.2
0.00
0.02
estimate
0.50
17
144
5
76
0.66
0.36
3.2
2.4
—
—
—
0
0
661
6696
0.92
0.35
40.8
21.4
138.97
139.67
mmol/l
8.54
652
6560
281
2698
1.06
0.35
4.9
3.9
—
0.80
—
0
10
662
6704
0.92
0.34
41.2
21.5
4.00
3.99
mmol/l
0.86
653
6561
153
1624
0.93
0.34
6.3
4.6
1.02
1.02
kg/l
0.85
107
1102
28
239
1.18
0.31
2.2
1.5
0.37
0.34
mg/l
0.10
17
99
7
98
0.71
0.31
3.7
1.2
—
—
—
0
0
7
99
0.70
0.31
3.7
1.2
—
—
—
0
0
7
100
0.70
0.30
3.7
1.2
—
—
—
0
0
7
100
0.70
0.30
3.7
1.2
—
—
—
0
0
21
175
1.21
0.30
2.8
2.5
54.22
76.58
ug/min
0.34
11
100
50
556
0.89
0.30
3.9
2.8
6.20
6.10
ph
0.41
41
390
8
107
0.75
0.29
2.9
2.0
183.25
216.83
pmol/l
—
8
98
7
57
1.23
0.29
4.1
1.4
—
—
—
0
0
17
204
0.83
0.27
7.9
10.7
—
—
—
0
0
9
77
1.17
0.24
1.7
1.2
—
—
—
0
0
9
77
1.17
0.24
1.0
1.1
—
—
—
0
0
7
95
0.73
0.22
3.7
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
18.18
—
0
10
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.62
—
0
7
6
51
1.18
0.19
2.5
4.3
—
42.05
u/ml
—
0
17
6
51
1.18
0.19
1.0
1.0
377.00
286.59
mg/l
—
6
44
7
59
1.19
0.18
1.3
1.1
—
—
—
0
0
11
91
1.21
0.17
1.1
1.7
—
—
—
0
0
7
61
1.15
0.17
2.3
2.2
—
—
—
0
0
155
1500
1.04
0.15
1.3
1.3
1.26
1.78
u/ml
0.29
38
380
9
78
1.16
0.15
1.0
1.1
—
—
—
0
0
602
6071
0.96
0.15
7.0
5.7
2.16
1.97
mu/l
0.68
550
5531
38
406
0.93
0.12
1.4
1.3
—
—
—
0
0
334
3390
0.97
0.12
2.2
2.2
92.97
95.63
pmol/l
0.55
179
1736
30
281
1.07
0.09
1.3
1.7
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
1.20
—
0
6
16
145
1.11
0.09
1.3
1.2
7.36
38.14
e6/l
0.69
11
107
26
244
1.07
0.08
1.1
1.1
—
—
—
0
0
6
74
0.81
0.07
4.0
1.2
—
—
—
0
0
7
82
0.85
0.07
1.0
1.1
—
148.50
—
0
14
7
83
0.84
0.07
1.7
1.3
—
—
—
0
0
18
192
0.94
0.05
6.2
5.0
—
—
—
0
0
653
6512
1.02
0.04
35.3
16.0
—
—
—
0
0
44
452
0.97
0.03
1.3
1.3
—
—
—
0
0
53
522
1.02
0.01
1.2
1.2
—
—
—
0
0
25
257
0.97
0.01
4.7
3.0
152.06
245.73
mg/l
0.90
16
95
13
136
0.96
0.00
1.1
1.2
—
—
—
0
0
10
98
1.02
0.00
1.2
1.1
—
—
—
0
0
18
178
1.01
0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
7
73
0.96
-0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
0.52
—
0
5
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
8
84
0.95
-0.00
1.3
1.4
—
—
nmol/l
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
36.33
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
28.26
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint J10_RESPCONDEXT and mortality.

Females

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 2.553 [2.22, 2.94] < 0.001
Birth year 0.995 [0.99, 1.0] 0.283

During the follow-up period (1.1.1998 — 31.12.2019), 1081 out of 2197 females with J10_RESPCONDEXT died.

Males

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 4.277 [3.44, 5.32] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 953 out of 1460 males with J10_RESPCONDEXT died.

Mortality risk

Mortality risk for people of age

years, who have J10_RESPCONDEXT.

N-year risk Females Males
1 0.267% 0.724%
5 1.56% 4.682%
10 3.869% 11.389%
15 6.993% 21.879%
20 12.541% 33.517%

Relationships between endpoints

↥

Index endpoint: J10_RESPCONDEXT – Respiratory conditions due to other external agents

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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