Transitory disorders of carbohydrate metabolism specific to fetus and newborn

P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P70
  • Cause of death: ICD-10 P70

2 out of 7 registries used, show all original rules.

526

4. Check minimum number of events

None

526

5. Include endpoints

None

526

6. Filter based on genotype QC (FinnGen only)

470

Control definitions (FinnGen only)

Control exclude
P16_TRANSITO_ENDOCR_METABOLIC_DISORD_SPECIFIC_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P7[0-4]
Name in latin
Perturbationes transitoriae metabolismi carbohydratorum fetus et neonati specificae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 43469 18662 24806
Only index persons 19536 8338 11198
Unadjusted period prevalence (%)
Whole population 0.62 0.53 0.69
Only index persons 0.38 0.31 0.43
Median age at first event (years)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 470 257 213
Unadjusted period prevalence (%) 0.09 0.09 0.10
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
497
Matched controls
4868
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
+∞
307.7
317
*
P70.0
ICD-10 Finland
Syndrome of infant of mother with gestational diabetes
+∞
153.3
140
*
P70.1
ICD-10 Finland
Syndrome of infant of a diabetic mother
+∞
94.2
88
*
P07.3
ICD-10 Finland
Other preterm infants
9.1
90.9
132
187
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
5.9
48.7
100
198
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
11.8
34.9
37
33
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
7.2
34.2
54
81
P08.1
ICD-10 Finland
Other heavy for gestational age infants
161.5
29.8
31
*
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
5.8
20.6
39
70
WX722
NOMESCO Finland
PEEP
4.9
19.4
45
97
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
5.4
15.8
32
61
P59.9
ICD-10 Finland
Neonatal jaundice, unspecified
3.9
12.9
40
108
P05.1
ICD-10 Finland
Small for gestational age
5.6
12.4
24
44
P08.0
ICD-10 Finland
Exceptionally large baby
37.8
12.1
15
*
P21.1
ICD-10 Finland
Mild and moderate birth asphyxia
7.8
10.3
23
30
P70.3
ICD-10 Finland
Iatrogenic neonatal hypoglycaemia
+∞
9.3
9
*
P05.0
ICD-10 Finland
Light for gestational age
9.1
9.0
18
20
P85
ICPC
Mental retardation
3.8
8.7
27
73
R62.0
ICD-10 Finland
Delayed milestone
2.4
8.6
60
259
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.5
7.9
52
219
P61.1
ICD-10 Finland
Polycythaemia neonatorum
79.6
7.4
8
*
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
4.4
6.8
17
39
Z38.3
ICD-10 Finland
Twin, born in hospital
11.0
6.2
11
10
RL130, ,
NOMESCO Finland
3.8
6.2
19
51

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
54
305
1.82
3.87
3.0
4.9
7.18
51.24
mg/mmol
0.50
43
253
52
315
1.69
2.96
2.8
4.3
91.63
145.84
mg/l
0.41
42
261
24
113
2.14
2.90
2.1
1.6
—
—
—
0
0
63
410
1.58
2.72
2.4
2.4
4.18
5.81
u/l
1.47
39
247
58
379
1.56
2.47
2.3
2.4
5.69
6.34
iu/l
0.23
43
240
392
3574
1.35
2.01
18.2
16.7
4.00
3.94
mmol/l
2.38
382
3461
245
2107
1.27
1.94
11.0
10.7
5.88
5.89
mmol/l
0.02
225
2006
15
70
2.13
1.90
1.0
1.0
1.35
1.41
g/l
0.23
15
70
7
22
3.15
1.84
2.9
3.3
21.14
32.82
u/l
—
7
22
204
1724
1.27
1.84
4.2
4.2
68.61
67.51
nmol/l
0.24
195
1645
391
3579
1.33
1.83
18.5
16.7
139.34
139.41
mmol/l
0.25
384
3485
41
268
1.54
1.79
4.8
6.5
0.40
0.38
%
0.02
20
103
41
268
1.54
1.79
6.1
7.2
0.00
0.01
%
0.49
19
92
128
1025
1.30
1.75
4.2
4.9
9.65
8.46
mmol/l
1.16
122
972
248
2157
1.25
1.71
7.0
6.7
138.78
131.16
u/l
0.52
235
2039
42
281
1.51
1.66
6.0
7.1
0.40
0.47
%
0.10
20
106
41
276
1.50
1.58
6.4
7.1
0.00
0.03
%
1.08
19
89
14
69
2.02
1.58
7.6
9.6
9.23
9.56
kpa
0.14
14
69
14
69
2.02
1.58
7.6
9.6
5.24
4.80
kpa
1.18
14
69
223
1930
1.24
1.57
20.6
18.1
1.23
1.23
mmol/l
0.11
212
1859
233
2037
1.23
1.47
17.1
16.0
1.23
1.23
mmol/l
0.68
219
1909
37
250
1.49
1.42
4.2
4.2
—
—
—
0
0
17
94
1.80
1.40
11.2
6.8
—
—
—
0
0
108
873
1.27
1.37
4.0
6.0
1.09
1.17
inr
0.57
85
731
19
110
1.72
1.36
3.9
4.8
—
—
—
0
0
12
216
0.53
1.35
1.2
1.2
—
—
—
0
0
16
88
1.81
1.35
7.2
8.7
7.40
7.39
ph
0.31
16
88
11
53
2.06
1.32
3.5
5.4
150.00
151.13
umol/l
—
6
31
10
189
0.51
1.32
1.3
1.2
—
—
—
0
0
104
842
1.27
1.30
4.6
3.9
0.00
0.00
estimate
-0.00
39
301
8
35
2.26
1.25
2.3
2.4
103.88
96.17
g/l
—
8
35
394
3667
1.25
1.24
11.0
10.8
26.53
24.49
u/l
1.09
386
3559
227
2015
1.19
1.14
10.7
12.2
—
—
—
0
0
139
1180
1.21
1.13
3.9
3.3
0.00
0.00
estimate
0.50
36
248
11
57
1.91
1.11
1.0
1.0
—
—
—
0
0
20
125
1.59
1.11
1.8
1.3
345.10
374.54
ug/g
—
10
74
152
1305
1.20
1.10
5.1
5.0
0.21
0.23
e6/l
0.04
114
933
54
411
1.32
1.09
8.2
10.7
52.47
49.94
ng/l
0.21
54
405
366
3397
1.21
1.09
4.4
4.1
2.14
2.02
mu/l
1.14
346
3229
103
851
1.23
1.09
4.0
3.2
0.00
0.00
estimate
-0.00
32
252
5
21
2.35
1.06
7.0
6.3
52.30
34.67
%
—
5
21
5
21
2.35
1.06
1.6
1.4
1078.00
1569.14
ml
—
5
21
17
104
1.62
1.03
2.2
2.2
0.00
0.00
estimate
—
7
52
37
269
1.38
1.01
7.0
8.8
235.63
311.90
mg/l
0.33
27
224
12
195
0.59
0.99
1.5
1.6
0.22
0.20
mg/l
—
5
79
161
1402
1.18
0.98
5.6
5.3
368.87
20.95
e6/l
0.50
123
1033
0
28
0.00
0.98
0.0
1.2
—
242.69
—
0
28
0
28
0.00
0.98
0.0
1.1
—
—
—
0
0
114
963
1.21
0.97
16.2
12.2
—
—
—
0
0
65
518
1.26
0.95
19.0
24.8
1.06
1.06
mg/l
0.02
65
513
32
230
1.39
0.94
2.0
1.9
0.00
0.00
estimate
—
7
70
13
204
0.61
0.94
1.0
1.2
—
—
—
0
0
111
940
1.20
0.92
2.9
2.7
—
—
—
0
0
269
2451
1.16
0.92
11.7
13.7
0.05
0.00
e9/l
0.49
210
1837
334
3095
1.17
0.92
4.1
3.6
14.58
14.44
pmol/l
0.53
306
2760
7
37
1.86
0.92
1.1
1.5
—
—
—
0
0
7
37
1.86
0.92
1.1
1.5
—
—
—
0
0
7
37
1.86
0.92
1.1
1.5
—
—
—
0
0
200
1783
1.17
0.91
4.4
4.0
0.00
0.00
estimate
-0.00
42
318
201
1794
1.16
0.90
4.5
4.0
0.00
3.95
estimate
0.50
39
311
11
62
1.75
0.89
1.9
1.3
—
—
—
0
0
8
42
1.88
0.88
2.3
5.2
5.27
4.91
kpa
—
8
42
257
2345
1.15
0.84
2.9
2.4
5.32
5.30
mmol/l
0.14
236
2146
14
209
0.65
0.83
1.9
1.4
1.18
1.14
g/l
0.29
14
202
103
877
1.19
0.81
3.8
4.5
1.97
2.61
e6/l
0.35
56
470
14
207
0.65
0.80
1.9
1.4
0.21
0.20
g/l
0.39
14
201
21
286
0.71
0.80
1.0
1.2
—
—
—
0
0
126
1096
1.17
0.78
16.9
12.4
7.40
7.41
ph
0.38
97
900
126
1096
1.17
0.78
16.7
12.4
5.12
4.99
kpa
1.54
120
1067
12
73
1.63
0.77
2.2
1.7
—
—
—
0
0
200
1802
1.15
0.77
4.4
4.0
0.00
0.00
estimate
-0.00
41
312
418
3969
1.20
0.75
10.4
9.1
—
—
—
0
0
470
4519
1.34
0.75
21.1
20.0
274.63
273.97
e9/l
0.07
451
4308
470
4519
1.34
0.75
20.9
19.9
85.94
85.78
fl
0.28
464
4454
10
58
1.70
0.75
3.0
5.7
22.55
26.92
ug/l
—
10
58
28
206
1.35
0.75
2.1
2.8
46.88
53.03
%
1.27
28
206
9
54
1.64
0.73
1.1
1.1
—
363.09
—
0
11
470
4521
1.34
0.73
23.1
21.7
39.31
40.22
%
0.59
464
4457
470
4521
1.34
0.73
21.0
19.9
4.64
4.61
e12/l
0.55
448
4298
470
4521
1.34
0.73
20.9
19.9
28.87
28.84
pg
0.11
464
4457
7
38
1.82
0.73
1.1
1.1
—
—
—
0
0
9
55
1.61
0.72
1.4
2.9
0.88
3.51
nmol/l
—
9
49
59
482
1.23
0.72
2.7
2.4
—
—
—
0
0
89
757
1.18
0.72
2.6
1.8
—
—
—
0
0
112
972
1.17
0.71
18.7
15.0
—
—
—
0
0
7
40
1.72
0.70
1.1
1.0
—
—
—
0
0
205
1860
1.14
0.70
5.2
5.5
28.31
25.46
u/l
0.50
189
1788
470
4524
1.32
0.69
21.9
20.4
133.22
132.58
g/l
0.45
464
4462
15
211
0.69
0.69
1.0
1.1
—
—
—
0
0
5
90
0.54
0.67
1.2
1.2
—
—
—
0
0
103
894
1.16
0.66
5.1
4.1
5.44
7.50
e6/l
1.15
95
796
153
1367
1.14
0.65
10.8
10.9
47.31
27.18
umol/l
2.68
136
1266
470
4528
1.31
0.65
21.0
19.9
6.98
6.95
e9/l
0.08
449
4302
24
307
0.75
0.64
1.6
1.4
—
—
—
0
0
12
77
1.54
0.64
2.6
2.4
—
—
—
0
0
29
358
0.78
0.61
3.3
2.2
141.29
159.89
u/ml
0.18
21
159
22
162
1.35
0.60
2.9
3.9
272.12
185.55
e6/l
0.46
17
106
412
3927
1.16
0.60
18.8
19.2
13.21
13.14
%
0.51
403
3871
16
112
1.41
0.58
6.5
5.8
1.90
2.42
ug/l
0.55
16
112
235
2169
1.12
0.58
3.5
3.0
2.51
2.56
mmol/l
0.48
223
2059
10
63
1.57
0.58
6.2
5.5
0.50
0.79
index
—
10
63
214
1967
1.12
0.57
3.6
2.9
1.11
1.07
mmol/l
0.28
206
1871
30
234
1.27
0.57
2.2
1.8
6.33
6.36
ph
0.07
18
149
245
2269
1.11
0.56
5.3
4.3
15.17
231.07
e6/l
—
6
28
19
139
1.35
0.55
1.4
1.2
201.67
219.84
iu/ml
—
6
38
21
265
0.77
0.53
3.7
2.5
—
—
—
0
0
9
61
1.45
0.53
15.9
11.1
5.19
5.82
pmol/l
—
9
61
136
1224
1.12
0.52
3.1
3.4
2.65
2.50
mg/l
0.41
124
1106
21
264
0.77
0.52
3.7
2.6
80.40
94.95
au/ml
—
10
113
238
2211
1.10
0.50
3.7
3.2
4.16
4.25
mmol/l
1.14
226
2118
153
1612
0.90
0.50
10.8
9.5
—
—
—
0
0
25
194
1.28
0.50
1.4
1.6
—
—
—
0
0
10
141
0.69
0.49
1.3
1.3
—
—
—
0
0
18
134
1.33
0.48
1.4
1.4
—
—
—
0
0
29
346
0.81
0.48
3.0
2.3
43.13
28.30
u/l
0.34
23
273
99
879
1.13
0.47
6.2
5.8
—
—
—
0
0
34
277
1.22
0.46
1.0
1.0
—
—
—
0
0
34
277
1.22
0.46
1.0
1.0
7.53
7.17
kpa
0.45
29
233
34
277
1.22
0.46
1.0
1.0
-2.13
-1.94
mmol/l
—
7
65
11
150
0.71
0.46
4.0
5.7
—
—
—
0
0
19
144
1.30
0.45
2.0
1.4
1.82
3.51
iu/ml
—
5
18
22
171
1.27
0.44
1.9
1.7
1008.78
1095.39
nmol/l
0.15
14
132
10
68
1.45
0.43
6.3
5.4
20.70
20.24
index
—
10
63
21
163
1.27
0.43
2.8
4.1
0.62
0.40
e9/l
0.67
15
101
14
102
1.35
0.43
6.1
2.1
1.37
2.21
mmol/l
—
9
81
8
55
1.43
0.42
1.5
3.0
0.46
1.93
ug/l
—
8
50
220
2050
1.09
0.42
4.4
3.4
35.56
35.19
mmol/mol
0.20
214
1938
5
32
1.54
0.41
3.4
2.6
30.00
32.03
pg
—
5
32
5
32
1.54
0.41
1.2
1.0
—
—
—
0
0
21
164
1.27
0.41
3.0
4.1
1655.31
1581.71
e6/l
0.08
16
111
5
33
1.49
0.40
1.0
1.1
—
104.71
ng/l
—
0
7
7
100
0.68
0.40
2.6
2.3
—
—
—
0
0
48
535
0.87
0.39
1.9
1.7
800.00
443.73
titre
—
8
75
112
1014
1.11
0.39
3.9
4.6
—
—
—
0
0
117
1063
1.10
0.38
11.1
12.9
1.31
0.82
mmol/l
1.32
90
854
14
177
0.77
0.38
1.2
1.1
—
—
—
0
0
117
1064
1.10
0.38
11.1
13.1
7.37
7.37
ph
0.07
80
747
31
258
1.19
0.36
30.0
20.9
15.61
15.59
kpa
0.01
31
250
31
258
1.19
0.36
30.0
20.9
5.19
5.35
kpa
0.53
31
250
39
332
1.16
0.35
2.7
2.1
5.72
7.90
nmol/l
0.98
31
296
20
159
1.24
0.35
2.9
3.9
608.20
561.55
e6/l
0.13
15
104
86
916
0.90
0.35
1.7
2.1
1.45
1.17
mmol/l
0.48
76
857
60
652
0.89
0.35
1.6
1.7
—
—
—
0
0
11
80
1.35
0.35
5.8
3.2
26.00
34.94
mmol/l
0.66
11
80
29
332
0.85
0.34
1.1
1.2
3.17
7.58
u/ml
2.03
18
223
12
152
0.77
0.34
6.2
10.3
24.07
23.93
mmol/l
0.06
12
145
31
260
1.18
0.34
30.1
20.8
7.40
7.37
ph
0.63
11
76
229
2157
1.07
0.32
3.6
3.0
1.33
1.40
mmol/l
2.94
217
2050
59
637
0.89
0.31
1.3
1.3
—
46.05
—
0
8
25
207
1.19
0.31
23.0
10.3
23.23
23.06
mmol/l
0.17
25
200
7
51
1.35
0.31
1.7
2.1
—
325.84
—
0
15
15
182
0.80
0.31
3.1
4.8
3.33
3.28
mmol/l
0.13
15
177
11
139
0.77
0.31
1.7
1.3
—
—
—
0
0
7
53
1.30
0.30
2.3
2.2
—
—
—
0
0
242
2288
1.07
0.30
4.2
4.0
51.17
47.88
ug/l
0.18
228
2198
164
1531
1.07
0.29
4.0
3.6
6.37
6.39
ph
0.11
83
696
33
368
0.87
0.29
2.0
2.0
—
—
—
0
0
25
209
1.18
0.29
1.2
1.7
0.64
4.10
u/ml
3.05
18
154
11
83
1.30
0.28
9.1
12.6
10.04
9.59
mg/l
0.10
11
78
117
1215
0.93
0.28
2.3
2.2
—
—
—
0
0
90
822
1.09
0.28
5.2
4.5
7.38
7.39
ph
0.42
61
563
32
275
1.15
0.27
1.0
1.0
3.16
3.28
kpa
0.17
27
232
23
192
1.18
0.27
2.3
2.3
—
—
—
0
0
23
192
1.18
0.27
2.3
2.3
—
—
—
0
0
23
192
1.18
0.27
2.3
2.3
—
—
—
0
0
23
192
1.18
0.27
2.3
2.3
—
—
—
0
0
61
651
0.91
0.27
1.6
1.7
—
—
—
0
0
56
500
1.11
0.27
2.9
2.3
10.44
35.87
ng/l
0.78
27
169
49
529
0.90
0.27
1.6
1.8
—
—
—
0
0
28
314
0.87
0.27
1.2
1.2
11.77
12.55
u/ml
0.05
19
202
12
93
1.27
0.26
3.4
3.5
21.29
21.26
mmol/l
0.00
12
87
17
138
1.21
0.26
1.2
1.3
—
—
—
0
0
5
73
0.67
0.26
1.0
1.1
—
—
—
0
0
62
659
0.91
0.26
1.7
1.7
—
—
—
0
0
46
408
1.11
0.25
1.9
2.1
—
—
—
0
0
53
475
1.10
0.24
3.4
2.4
497.01
9173.24
u/l
3.43
16
129
21
176
1.18
0.24
40.5
25.0
16.02
15.58
%
0.35
21
171
176
1659
1.06
0.23
6.9
6.3
45.39
52.32
e6/l
0.12
127
1070
62
655
0.92
0.23
1.6
1.7
—
—
—
0
0
15
122
1.21
0.23
2.3
1.6
0.12
0.23
nmol/l
—
10
92
23
196
1.16
0.22
39.9
26.2
95.41
95.74
%
0.05
23
196
5
41
1.20
0.21
2.0
7.6
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
0.50
—
0
10
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
12.8
—
33.55
—
0
11
8
99
0.79
0.21
1.5
1.3
10.65
14.13
u/ml
—
8
92
26
287
0.88
0.21
2.3
2.1
—
—
—
0
0
54
489
1.09
0.21
23.8
20.3
1.56
1.33
mmol/l
0.83
54
477
0
12
0.00
0.21
0.0
1.4
—
117.25
—
0
12
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
42
1.17
0.21
8.4
7.4
—
—
—
0
0
0
13
0.00
0.20
0.0
1.4
—
17699.88
—
0
8
44
468
0.91
0.19
6.1
4.2
2356.38
1068.68
ng/l
0.55
29
254
6
52
1.13
0.18
1.0
1.2
—
—
—
0
0
6
52
1.13
0.18
1.5
1.6
356.17
525.20
pmol/l
—
6
45
7
59
1.16
0.18
2.9
2.9
—
—
—
0
0
44
465
0.92
0.17
1.2
1.2
3.15
3.36
u/ml
0.06
32
340
75
695
1.07
0.17
4.3
3.7
13.19
13.63
umol/l
0.22
70
673
7
60
1.14
0.17
1.3
1.1
—
—
—
0
0
5
65
0.75
0.17
1.0
1.1
—
—
—
0
0
92
860
1.06
0.17
4.3
3.8
557.14
581.41
mosm/kgh2o
0.39
84
756
137
1296
1.05
0.16
1.6
1.6
—
—
—
0
0
92
861
1.06
0.16
1.3
1.3
—
—
—
0
0
196
1871
1.04
0.16
1.9
1.8
1.45
1.46
g/l
0.02
106
991
28
301
0.91
0.16
1.1
1.2
0.02
1.08
u/ml
1.47
15
165
66
613
1.06
0.15
1.5
1.5
270.19
462.82
u/ml
0.55
58
576
14
157
0.87
0.14
1.2
1.3
1.18
23.84
u/ml
—
9
128
14
157
0.87
0.14
1.1
1.4
0.14
2.51
u/ml
—
9
113
415
4029
1.05
0.14
14.6
13.3
21.91
23.10
mg/l
0.31
317
2883
8
97
0.80
0.13
1.1
1.0
1.31
1.49
g/l
—
8
97
70
654
1.06
0.13
5.4
6.4
1.56
1.97
mg/l
0.38
51
480
22
195
1.11
0.13
41.5
26.2
0.69
0.68
%
0.01
22
195
15
130
1.13
0.12
3.3
2.8
—
—
—
0
0
15
165
0.89
0.12
9.0
22.4
69.43
69.58
%
0.01
15
165
60
616
0.95
0.12
1.6
1.7
—
—
—
0
0
23
206
1.10
0.12
1.3
1.3
219.38
208.31
miu/ml
0.06
13
90
43
445
0.94
0.11
1.8
2.2
—
—
—
0
0
83
784
1.04
0.11
1.9
2.0
—
—
—
0
0
11
123
0.87
0.11
1.0
1.2
—
—
—
0
0
11
94
1.15
0.10
1.9
1.5
—
—
—
0
0
133
1334
0.97
0.10
3.8
4.3
—
—
estimate
—
0
0
19
203
0.91
0.10
1.4
1.7
15.79
13.98
u/ml
0.05
11
143
10
85
1.16
0.10
1.0
1.0
—
—
—
0
0
5
45
1.09
0.09
1.2
1.3
108.00
113.49
pmol/l
—
5
45
33
343
0.94
0.09
1.6
1.5
—
—
—
0
0
24
218
1.08
0.09
1.4
1.2
3.04
2.99
mmol/l
0.10
12
119
78
739
1.04
0.09
1.8
1.7
—
—
—
0
0
76
720
1.04
0.09
4.4
4.8
—
—
—
0
0
22
232
0.93
0.09
8.7
18.1
0.62
0.59
%
0.16
22
232
63
595
1.04
0.08
2.1
1.9
—
—
—
0
0
6
57
1.03
0.08
1.5
4.1
—
—
—
0
0
5
61
0.80
0.08
1.0
1.1
—
—
—
0
0
5
62
0.79
0.08
5.4
2.9
—
—
—
0
0
5
63
0.78
0.08
1.0
1.1
—
—
—
0
0
17
181
0.92
0.08
3.1
5.0
11.90
7.57
e6/l
—
10
124
17
181
0.92
0.08
3.2
5.0
137.17
1023.10
e6/l
0.68
12
128
7
66
1.04
0.08
1.7
3.0
119.57
172.58
ug/g
—
7
60
46
432
1.05
0.08
15.2
18.5
106.24
105.75
mmol/l
0.30
46
432
46
432
1.05
0.08
1.8
2.1
—
—
—
0
0
7
67
1.02
0.07
1.0
1.2
—
—
—
0
0
12
130
0.90
0.07
5.2
3.1
140.42
134.83
g/l
0.23
12
117
7
81
0.84
0.07
1.4
1.7
—
—
—
0
0
7
83
0.82
0.07
1.1
1.1
—
—
—
0
0
88
842
1.03
0.06
1.9
1.7
—
—
—
0
0
19
199
0.93
0.06
6.2
4.1
0.02
0.12
e6/l
3.26
19
190
16
169
0.92
0.06
6.8
6.9
26.89
12.85
umol/l
0.44
16
149
126
1256
0.98
0.06
10.5
10.5
38.17
38.09
g/l
0.05
121
1206
55
556
0.97
0.06
9.2
9.3
5.37
5.96
umol/l
0.28
43
463
21
218
0.94
0.05
2.2
1.9
—
—
—
0
0
275
2672
1.02
0.05
11.5
12.3
0.21
0.22
e9/l
0.49
232
2231
45
427
1.04
0.05
1.3
1.2
9.29
16.63
iu/ml
—
7
75
252
2488
0.98
0.05
11.3
11.6
0.60
0.62
%
0.27
247
2388
62
622
0.97
0.04
1.8
1.7
—
—
—
0
0
10
89
1.10
0.04
3.3
4.1
2.50
3.32
e9/l
—
10
89
25
256
0.95
0.04
1.2
1.4
—
—
—
0
0
162
1603
0.98
0.04
2.1
2.3
—
—
—
0
0
264
2602
0.99
0.03
10.8
11.3
0.59
0.57
e9/l
0.62
224
2114
50
478
1.03
0.03
1.2
1.3
8.35
5.83
u/ml
0.37
35
364
22
206
1.05
0.03
1.1
1.1
—
—
—
0
0
12
126
0.93
0.03
10.8
26.4
10.63
11.47
%
0.63
12
126
13
119
1.07
0.03
2.5
4.5
—
—
—
0
0
281
2738
1.01
0.03
12.9
13.2
3.33
3.41
e9/l
0.27
237
2232
19
195
0.95
0.03
1.6
1.3
—
—
—
0
0
264
2600
0.99
0.03
10.8
11.3
0.04
0.04
e9/l
0.66
224
2114
253
2492
0.99
0.03
11.3
11.6
3.07
3.28
%
0.68
245
2387
14
129
1.06
0.03
2.3
2.1
—
—
—
0
0
49
470
1.02
0.02
1.1
1.3
0.35
1.13
u/ml
2.18
30
340
29
293
0.97
0.02
1.8
1.3
—
—
—
0
0
51
490
1.02
0.02
4.7
6.4
66.60
62.64
e9/l
0.41
30
295
19
194
0.96
0.02
1.6
1.3
—
—
—
0
0
44
422
1.02
0.02
2.3
2.3
0.85
0.93
g/l
0.59
44
409
10
91
1.08
0.02
1.4
1.6
606.60
373.50
mu/l
—
5
74
69
668
1.01
0.01
2.1
1.9
—
—
—
0
0
201
1960
1.01
0.01
1.9
1.9
1.65
3.85
u/ml
1.55
40
347
92
894
1.01
0.01
1.7
1.6
106.40
98.26
pmol/l
1.28
47
467
11
102
1.06
0.00
1.5
2.0
133.73
142.52
ng/l
0.21
11
97
11
102
1.06
0.00
4.1
1.9
292.27
295.18
mosm/kgh2o
0.27
11
71
95
936
0.99
0.00
3.7
3.0
1.02
1.02
kg/l
0.06
60
575
16
152
1.03
0.00
7.3
3.8
—
—
—
0
0
10
93
1.05
0.00
1.7
1.3
—
—
—
0
0
52
506
1.01
0.00
1.2
1.3
3.72
3.02
u/ml
0.11
37
364
10
95
1.03
0.00
3.4
2.6
—
2.73
—
0
6
259
2534
1.00
0.00
10.7
11.2
47.66
48.17
%
0.24
254
2458
42
407
1.01
0.00
1.3
1.3
211.24
114.79
u/ml
0.59
15
113
28
276
0.99
0.00
1.3
1.6
—
—
—
0
0
20
197
0.99
0.00
28.0
20.2
120.00
120.35
g/l
0.02
20
192
77
751
1.01
0.00
2.9
3.5
82.30
56.02
u/l
0.89
69
701
17
171
0.97
0.00
3.1
5.2
—
—
—
0
0
99
968
1.00
0.00
3.0
3.2
145.11
81.11
ug/g
0.36
79
778
10
102
0.96
0.00
1.2
1.4
14.97
7.74
u/ml
—
10
96
264
2587
1.00
0.00
11.1
11.4
37.44
36.29
%
0.78
257
2499
42
410
1.00
0.00
3.4
2.6
4.00
4.07
e9/l
0.04
36
367
255
2500
1.00
0.00
11.3
11.6
8.67
8.40
%
0.88
245
2389
41
400
1.00
0.00
1.3
1.2
1.01
9.62
u/ml
1.50
16
113
7
74
0.93
0.00
2.0
1.4
—
—
—
0
0
7
71
0.97
0.00
2.3
4.6
22.24
23.70
mmol/l
—
7
66
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
220.40
—
0
5
7
74
0.93
0.00
2.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
14.30
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
271
2651
1.00
-0.00
10.7
11.3
2.55
2.45
e9/l
0.47
233
2231
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
4.00
—
0
6
9
97
0.91
-0.00
1.8
1.0
1.13
0.78
g/l
—
9
97
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
7.35
—
0
6
0
6
0.00
-0.00
0.0
22.3
—
—
—
0
0
6
60
0.98
-0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
24.00
—
0
6
5
52
0.94
-0.00
1.2
2.5
23.60
21.73
u/ml
—
5
41
6
60
0.98
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
18.02
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
422.00
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
0.99
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
97
0.91
-0.00
1.2
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO and mortality.

Females

Parameter HR [95% CI] p-value
P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO 1.634 [1.25, 2.13] < 0.001
Birth year 0.989 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 17625 females with P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO died.

Males

Parameter HR [95% CI] p-value
P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO 1.08 [0.86, 1.35] 0.502
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 23411 males with P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO died.

Mortality risk

Mortality risk for people of age

years, who have P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO.

N-year risk Females Males
1 0.155% 0.296%
5 0.759% 1.406%
10 1.871% 3.717%
15 3.651% 6.688%
20 6.531% 10.989%

Relationships between endpoints

Index endpoint: P16_TRANSITO_DISORD_CARBOH_METABOLISM_SPECIFIC_FETUS_NEWBO – Transitory disorders of carbohydrate metabolism specific to fetus and newborn

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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