Benign neoplasm: Kidney

CD2_BENIGN_KIDNEY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D30.0&
  • Hospital discharge: ICD-9 2230
  • Hospital discharge: ICD-8 2230
  • Cause of death: ICD-10 D30.0&
  • Cause of death: ICD-9 2230
  • Cause of death: ICD-8 2230

2 out of 7 registries used, show all original rules.

1498

4. Check minimum number of events

None

1498

5. Include endpoints

None

1498

6. Filter based on genotype QC (FinnGen only)

1325

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D30
Name in latin
Neoplasma benignum renis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6609 3971 2585
Only index persons 5892 3682 2210
Unadjusted period prevalence (%)
Whole population 0.10 0.11 0.07
Only index persons 0.12 0.14 0.08
Median age at first event (years)
Whole population 63.31 61.47 66.18
Only index persons 62.69 60.74 65.94

-FinnGen-

Key figures

All Female Male
Number of individuals 1325 786 539
Unadjusted period prevalence (%) 0.27 0.28 0.25
Median age at first event (years) 62.68 59.56 67.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1386
Matched controls
13857
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
60.9
307.7
611
177
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
4503599627370496.0
307.7
1321
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
21.1
300.1
237
134
KAD00
NOMESCO Finland
Partial nephrectomy
80.0
232.0
124
17
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
25.8
210.9
150
65
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
44.9
174.5
104
25
KA1AE
NOMESCO Finland
Kidney ultrasound examination
12.0
159.6
169
158
KAC10
NOMESCO Finland
Total nephrectomy with capsule
25.5
119.0
84
35
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
24.8
115.1
82
35
N28.1
ICD-10 Finland
Cyst of kidney
9.5
68.7
83
92
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
18.3
65.6
53
30
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
14.7
59.8
54
38
JN3AD
NOMESCO Finland
Abdominal CT examination
3.1
59.4
309
1185
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
45.0
43
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
15.4
44.4
39
26
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
44.3
280
1177
UKC02
NOMESCO Finland
Cystoscopy
2.5
43.3
333
1540
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.8
41.9
137
389
PC5DT
NOMESCO Finland
Embolisation of tumor of kidney
419.5
41.3
41
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
40.0
596
3620
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.7
39.5
96
218
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
37.9
149
477
N02AX02
ATC
tramadol; systemic, rectal
2.0
33.0
700
4730
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
8.3
32.6
43
53
KH1AD
NOMESCO Finland
CT of urinary organs
4.0
31.9
93
243
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
8.3
30.8
41
51
U14
ICPC
Kidney symptom/complaint
5.9
30.5
56
99
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
8.8
28.5
36
42
N02BE01
ATC
paracetamol; systemic, rectal
3.3
27.6
1299
11366
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
27.5
421
2510
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
6.5
27.4
45
71
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
26.6
132
483
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
8.0
26.5
36
46
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
25.9
218
1030
22300
ICD-8 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
+∞
24.0
23
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.3
23.5
61
146
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
23.3
179
812
R31
ICD-10 Finland
Unspecified haematuria
2.3
23.1
197
934
KAC00
NOMESCO Finland
Nephrectomy
21.1
21.3
31
15
B01AB10
ATC
tinzaparin; parenteral
2.2
20.9
199
986
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.1
20.8
88
293
D30.3
ICD-10 Finland
Benign neoplasm: Bladder
37.8
20.8
26
7
PC5ET
NOMESCO Finland
Extensive embolisation of tumor of kidney
213.0
20.6
21
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
20.1
292
1685
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
19.5
739
5608
XKD00
NOMESCO Finland
Uroflowmetry
2.0
19.3
257
1440
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.4
18.8
138
611
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
18.2
932
7589
Z3231
NOMESCO Finland
Registered nurse
1.7
17.9
404
2656
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
17.6
351
2227
JN4AD
NOMESCO Finland
Body CT examination
2.0
17.5
208
1117
R4110
NOMESCO Finland
Physiotherapy
1.7
17.4
421
2816
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
17.3
307
1881
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
16.6
318
1989
WX402
NOMESCO Finland
General anaesthesia
1.8
16.5
330
2090
8260/3-C64.9
ICD-O-3
Papillary adenocarcinoma, NOS, of kidney, NOS
20.3
16.4
24
12
B01AB05
ATC
enoxaparin; parenteral
1.6
16.3
483
3396
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
16.2
249
1456
ZXA00
NOMESCO Finland
Right side
1.7
15.8
399
2688
ZXA05
NOMESCO Finland
Left side
1.7
15.2
371
2475
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
4.3
14.6
38
91
A02BC02
ATC
pantoprazole; systemic
1.6
14.5
981
8298
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
4.9
14.5
32
67
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.7
14.5
45
123
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.5
14.5
50
147
KA3LT
NOMESCO Finland
Njurlesion coagulation
42.9
14.1
17
*
N20.0
ICD-10 Finland
Calculus of kidney
3.6
13.9
45
127
A02BC05
ATC
esomeprazole; systemic
1.6
13.8
578
4368
S18
ICPC
Laceration/cut
1.5
13.6
688
5413
D06
ICPC
Abdominal pain localized other
2.1
13.6
132
656
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
26.0
13.4
18
7
N18.8
ICD-10 Finland
Other chronic renal failure
3.4
13.4
47
140
J01MA02
ATC
ciprofloxacin; systemic
1.5
13.3
551
4145
G04CA02
ATC
tamsulosin; oral
1.6
13.0
335
2255
J01DB01
ATC
cefalexin; oral
1.7
12.9
1120
9898
JN4CD
NOMESCO Finland
Very extensive body CT
2.7
12.8
70
269
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
12.8
181
1027
D01
ICPC
Abdominal pain/cramps general
1.9
12.5
177
1003
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
131.1
12.5
13
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.7
12.4
23
41
N20.1
ICD-10 Finland
Calculus of ureter
2.7
12.3
64
240
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
11.9
518
3913
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.8
11.9
206
1242
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
30.3
11.7
15
5
D30.9
ICD-10 Finland
Benign neoplasm: Urinary organ, unspecified
+∞
11.5
11
*
Q85.1
ICD-10 Finland
Tuberous sclerosis
+∞
11.5
11
*
D30.1
ICD-10 Finland
Benign neoplasm: Renal pelvis
+∞
11.5
11
*
JN4BD
NOMESCO Finland
Extensive body CT
1.9
11.5
165
940
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
11.4
430
3146
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
11.4
198
1194
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
11.3
101
485
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
11.3
170
982
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
11.3
41
125
D02
ICPC
Abdominal pain epigastric
2.2
10.9
98
473
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.2
10.7
41
129
UJF32
NOMESCO Finland
Coloscopy
1.5
10.7
381
2746
Z3226
NOMESCO Finland
Physiotherapist
1.6
10.7
252
1650
WX002
NOMESCO Finland
Sedation and analgesia
1.6
10.7
277
1857
WX704
NOMESCO Finland
Intubation
2.0
10.6
122
645
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.6
576
4526
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
10.6
948
8199
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
10.5
291
1981
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
10.5
320
2229
R51.80
ICD-10 Finland
Headache
1.7
10.4
207
1294
M54.5
ICD-10 Finland
Low back pain
1.5
10.3
485
3701
C08CA01
ATC
amlodipine; oral
1.5
10.1
561
4413
A02BC01
ATC
omeprazole; systemic
1.5
10.1
377
2742
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
9.9
491
3775
Z2221
NOMESCO Finland
Medical doctor
1.5
9.9
362
2617
7125
FHL
Nephrectomy (extrrafascial)
16.8
9.9
15
9
J01EA01
ATC
trimethoprim; systemic
1.5
9.8
354
2553
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
5.3
9.6
19
36
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
9.5
160
954
V03AE01
ATC
polystyrene sulfonate; oral
3.9
9.4
27
70
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
9.4
499
3878
R03AC02
ATC
salbutamol; inhalant
1.4
9.3
720
5991
L15
ICPC
Knee symptom/complaint
1.5
9.1
356
2604
P01AB01
ATC
metronidazole; oral, rectal
1.4
9.1
530
4184
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
9.1
379
2808
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
7.1
9.0
21
30
TK800
NOMESCO Finland
Hemodialysis
3.1
9.0
36
117
R39.1
ICD-10 Finland
Other difficulties with micturition
2.6
8.8
51
203
A02BC03
ATC
lansoprazole; oral
1.5
8.7
397
2988
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
8.7
136
793
A97
ICPC
No disease
1.5
8.7
274
1914
H02AB06
ATC
prednisolone; systemic
1.4
8.5
641
5273
L03
ICPC
Low back symptom/complaint
1.5
8.5
388
2918
L05
ICPC
Flank/axilla symptom/complaint
1.9
8.5
99
526
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.7
8.5
26
71
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.3
8.4
21
49
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.4
334
2448
J01AA02
ATC
doxycycline; systemic
1.5
8.3
1051
9443
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
8.3
399
3033
J01FA10
ATC
azithromycin; systemic
1.4
8.1
705
5925
205
Kela drug reimbursment
Chronic hypertension
1.4
8.1
376
2835
U79
ICPC
Neoplasm urinary tract unspecified
33.5
8.1
10
*
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
17.3
8.1
12
7
Z90.5
ICD-10 Finland
Acquired absence of kidney
17.3
8.1
12
7
ZXE00
NOMESCO Finland
One hour or less
1.4
8.0
496
3936
C64.80
ICD-10 Finland
Wilms tumour
22.2
8.0
11
5
U01
ICPC
Dysuria/painful urination
1.8
7.9
115
657
R21
ICPC
Throat symptom/complaint
1.6
7.9
224
1526
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
7.9
97
525
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
7.9
101
554
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.9
392
2992
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.8
144
880
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
4.1
7.8
21
52
U07
ICPC
Urine symptom/complaint other
1.8
7.8
127
750
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
7.8
179
1161
C09CA01
ATC
losartan; oral
1.4
7.7
359
2704
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
45.2
7.7
9
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
7.7
184
1204
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.0
7.7
78
395
S29
ICPC
Skin symptom/complaint other
1.5
7.7
278
1995
R01AD58
ATC
fluticasone, combinations; nasal
1.5
7.6
284
2048
J01FA09
ATC
clarithromycin; systemic
1.4
7.6
386
2951
WZC30
NOMESCO Finland
Teaching
1.5
7.6
230
1587
N03AX16
ATC
[U] pregabalin
1.5
7.6
310
2277
XJH00
NOMESCO Finland
Transanal ultrasonography
2.0
7.6
85
446
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
7.6
171
1103
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
11.9
7.6
13
11
K30
ICD-10 Finland
Functional dyspepsia
1.7
7.5
157
992
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.5
214
1457
KA1AE, ,
SPAT
10.1
7.5
14
14
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
2.9
7.5
34
119
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
7.5
116
675
R35
ICD-10 Finland
Polyuria
1.8
7.5
103
579
C08CA13
ATC
lercanidipine; oral
1.5
7.4
215
1470
JFB00
NOMESCO Finland
Partial resection of small intestine
3.3
7.4
27
83
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.3
340
2559
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.7
7.3
38
144
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
7.3
48
204
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.2
569
4680
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.8
7.2
117
692
KA6KT
NOMESCO Finland
Sclerotherapy of kidney cyst
30.2
7.2
9
*
KB1CG
NOMESCO Finland
Extensive MRI examination of urinary tract with high intensity magnet
30.2
7.2
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.5
7.1
235
1653
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
7.1
85
457
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.3
7.0
51
226
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.0
227
1592
G04CA01
ATC
alfuzosin; oral
1.6
6.9
162
1054
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
7.6
6.9
15
20
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.9
558
4598
SPAT1153
SPAT
Removal of sutures
1.4
6.8
424
3347
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.1
6.8
65
322
G04BD08
ATC
solifenacin; oral
1.8
6.8
96
544
U75
ICPC
Malignant neoplasm of kidney
16.8
6.7
10
6
A04
ICPC
Weakness/tiredness general
1.5
6.7
209
1450
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.7
234
1664
S04
ICPC
Lump/swelling localized
1.6
6.7
146
934
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
6.7
310
2327
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.7
478
3859
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.7
546
4500
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
6.6
133
835
A98
ICPC
Health maint/preventive medicine
1.8
6.6
1306
12458
J02AC01
ATC
fluconazole; systemic
1.4
6.5
480
3889
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.0
6.5
27
90
R05
ICD-10 Finland
Cough
1.4
6.5
280
2072
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.5
315
2383
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
3.1
6.5
26
85
N17
ICPC
Vertigo/dizziness
1.5
6.4
183
1245
G04BD12
ATC
mirabegron; oral
1.5
6.4
179
1212
M03BX02
ATC
tizanidine; oral
1.3
6.4
774
6740
N01
ICPC
Headache
1.7
6.4
129
809
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.0
6.3
64
324
C09CA06
ATC
candesartan; oral
1.4
6.3
318
2419
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
5.2
6.3
18
35
M79.6
ICD-10 Finland
Pain in limb
1.3
6.3
583
4884
KCV04
NOMESCO Finland
Distension of bladder with fluid
3.9
6.3
18
47
G04CB01
ATC
finasteride; oral
1.6
6.3
143
925
PC5NT
NOMESCO Finland
Endovascular embolisation for kidney bleeding with radiological guidance
+∞
6.3
6
*
N19
ICD-10 Finland
Unspecified kidney failure
2.1
6.2
58
285
G47.3
ICD-10 Finland
Sleep apnoea
1.4
6.2
293
2203
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
4.0
6.2
17
43
C07AB07
ATC
bisoprolol; oral
1.3
6.2
676
5795
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.1
300
2270
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
2.9
6.1
27
94
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
3.1
6.1
24
78
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.0
210
1491
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1192
9776
2.56
33.40
10.2
8.7
79.87
80.02
u/l
0.04
1157
9273
1058
8311
2.15
31.94
6.5
5.0
1704.90
1864.44
e6/l
—
10
142
655
4376
1.94
31.44
4.6
3.5
76.78
82.90
e6/l
0.04
511
3382
915
6844
1.99
31.29
10.0
7.4
1.22
1.21
mmol/l
0.84
819
5920
829
6008
1.94
30.98
6.3
5.2
35.76
35.32
g/l
1.52
792
5648
929
7004
1.99
30.81
6.9
6.7
10.70
11.61
umol/l
2.37
890
6688
548
3470
1.96
30.63
4.0
3.2
0.15
0.04
0.54
13
85
253
1209
2.34
29.57
1.4
1.4
—
—
—
0
0
839
6163
1.91
29.43
8.6
6.6
1.22
1.21
mmol/l
1.99
790
5689
701
4910
1.86
27.98
5.5
4.1
65.30
98.21
e6/l
0.90
523
3530
816
6020
1.86
27.35
3.1
2.9
—
—
estimate
—
0
0
843
6288
1.87
27.22
15.6
16.5
1.22
1.28
inr
2.17
699
5264
568
3755
1.87
26.95
4.4
3.4
0.18
0.46
e6/l
6.81
437
2792
800
6011
1.78
23.75
6.6
6.5
58.05
57.67
%
0.40
763
5744
225
1118
2.21
23.60
5.5
3.7
101.52
88.04
ng/l
1.19
200
964
869
6706
1.79
23.38
5.1
4.2
13.67
3.36
estimate
0.53
187
1463
364
2166
1.92
23.28
3.9
3.2
1.66
2.55
e6/l
1.97
195
1088
859
6622
1.78
23.02
5.0
4.2
0.00
0.00
estimate
0.50
180
1418
419
2619
1.86
22.96
3.8
3.0
514.57
525.08
mosm/kgh2o
0.48
376
2294
871
6757
1.78
22.68
5.1
4.2
5.66
0.23
estimate
0.47
177
1369
928
7347
1.80
22.39
10.1
10.0
4.23
4.13
e9/l
0.66
789
6413
796
6038
1.75
22.22
6.9
6.7
8.71
8.95
%
1.71
752
5657
795
6029
1.75
22.20
6.9
6.7
0.71
0.68
%
1.12
750
5651
795
6031
1.75
22.16
6.8
6.6
2.84
2.81
%
0.17
749
5653
385
2367
1.87
22.10
3.7
3.1
1.02
1.10
e6/l
0.13
217
1290
805
6145
1.74
21.78
6.7
6.6
26.76
27.10
%
0.37
770
5822
468
3077
1.79
21.44
3.4
2.7
4.10
5.82
e6/l
3.09
429
2807
321
1880
1.92
21.30
8.7
5.5
1.05
1.03
mmol/l
1.14
297
1727
593
4221
1.71
20.18
2.9
2.6
62.76
80.40
u/l
0.44
548
3898
711
5316
1.69
20.11
4.4
3.7
6.18
6.25
ph
0.96
393
2975
488
3301
1.74
19.93
4.7
4.2
92.24
88.80
%
2.38
482
3239
692
5149
1.69
19.83
2.5
2.2
—
—
—
0
0
948
7678
1.74
19.75
6.0
5.2
6.68
6.77
mmol/l
0.78
917
7333
252
1400
1.98
19.36
6.7
8.2
123.00
120.11
g/l
1.58
246
1370
264
1497
1.94
19.09
6.4
7.8
95.88
95.48
%
0.43
254
1452
589
4265
1.66
18.24
3.0
2.5
—
—
—
0
0
283
1668
1.87
18.11
6.4
7.5
7.41
7.41
ph
0.41
137
929
113
464
2.56
18.11
2.6
3.3
313.29
333.23
mg/l
0.10
56
187
281
1664
1.86
17.68
6.3
7.5
5.19
5.11
kpa
0.88
269
1608
281
1665
1.86
17.64
6.3
7.5
12.54
12.18
kpa
0.62
270
1608
225
1240
1.97
17.58
10.3
7.3
10.92
10.06
mmol/l
1.07
218
1190
280
1659
1.86
17.57
6.2
7.5
0.48
1.00
mmol/l
1.66
235
1384
165
812
2.17
17.49
7.4
9.8
16.34
15.77
%
1.91
160
785
621
4602
1.63
17.26
4.6
4.1
15.39
8.72
mg/mmol
1.95
408
2834
844
6753
1.64
17.12
7.1
6.6
0.19
0.19
e9/l
0.37
729
5883
1298
11809
2.56
17.02
22.8
17.8
26.86
25.03
mg/l
1.05
1128
9866
570
4151
1.63
16.89
6.4
4.3
7.39
7.40
ph
1.82
437
3012
832
6661
1.62
16.58
6.9
6.5
1.82
1.91
e9/l
0.81
728
5846
622
4645
1.61
16.53
3.7
3.4
6.74
7.22
mmol/l
2.40
540
3900
602
4463
1.62
16.46
6.5
6.3
—
—
—
0
0
606
4503
1.61
16.40
3.8
3.5
80.32
48.20
mg/l
1.61
398
2847
820
6562
1.61
16.20
6.8
6.4
0.04
0.04
e9/l
0.38
696
5622
223
1259
1.92
16.14
2.4
2.4
38.82
37.49
u/l
0.09
198
1065
461
3224
1.64
15.81
2.6
2.5
—
—
—
0
0
816
6547
1.60
15.73
6.8
6.4
0.59
0.59
e9/l
0.05
694
5604
752
5924
1.59
15.63
3.0
2.5
79.45
78.79
nmol/l
0.28
691
5303
572
4268
1.58
14.74
3.9
3.3
—
—
—
0
0
121
564
2.25
14.61
2.7
2.7
—
—
—
0
0
563
4249
1.55
13.44
3.6
3.3
29.55
32.42
u/l
1.77
537
4018
1318
12248
2.55
13.40
28.9
21.3
3.99
3.98
mmol/l
0.64
1307
12005
1316
12231
2.50
13.19
28.4
21.1
139.75
139.67
mmol/l
0.61
1306
12004
516
3866
1.53
12.50
5.0
4.5
—
—
—
0
0
50
162
3.16
12.45
1.3
1.3
—
—
nmol/l
—
0
0
928
7892
1.53
12.10
3.9
3.4
58.35
51.61
u/l
0.78
886
7365
55
192
2.94
12.06
1.5
1.3
0.63
9.98
nmol/l
0.50
55
182
241
1514
1.72
12.04
2.9
2.7
5.93
8.46
umol/l
2.66
217
1349
204
1226
1.78
11.90
8.6
8.2
—
—
—
0
0
55
196
2.88
11.63
1.5
1.3
0.22
0.44
nmol/l
—
5
14
50
169
3.03
11.61
1.4
1.2
0.22
0.19
nmol/l
0.29
45
134
371
2621
1.57
11.54
4.7
4.0
143.15
364.80
ng/l
3.10
305
2114
314
2153
1.59
11.05
3.9
2.6
2.33
2.29
g/l
0.55
296
1995
1292
12033
2.08
10.94
21.0
16.0
—
—
—
0
0
712
5817
1.46
10.71
3.8
3.1
124.06
130.64
ug/l
0.38
671
5394
295
2009
1.59
10.64
4.0
2.6
20.52
22.35
%
1.59
282
1876
467
3526
1.49
10.46
4.4
3.7
2.19
0.05
estimate
0.62
140
1113
162
945
1.81
10.40
7.3
9.3
94.50
93.91
%
0.59
162
939
599
4754
1.46
10.38
3.9
3.7
2.36
2.36
mmol/l
0.69
545
4310
1327
12527
2.39
10.21
32.1
23.5
89.41
78.35
umol/l
10.25
1322
12388
1085
9695
1.55
9.97
30.0
22.1
13.80
13.75
%
0.71
1079
9570
1258
11671
1.84
9.90
5.9
5.3
1.44
1.48
mmol/l
3.12
1176
10722
1264
11746
1.86
9.86
6.0
5.4
4.54
4.59
mmol/l
1.15
1191
10876
446
3374
1.47
9.76
3.1
2.9
355.58
342.34
umol/l
1.80
387
2939
1228
11352
1.72
9.26
8.0
6.9
39.83
39.79
mmol/mol
0.05
1166
10553
224
1476
1.62
9.16
2.5
2.3
117.96
131.17
ug/g
0.31
183
1175
200
1283
1.65
9.10
6.7
7.2
1.15
1.35
mmol/l
3.88
194
1262
719
6008
1.41
8.87
2.5
2.2
97.60
95.89
pmol/l
0.43
386
3114
322
2319
1.51
8.86
4.0
2.6
11.84
12.66
umol/l
1.15
307
2160
82
402
2.10
8.77
5.8
6.4
1.27
1.32
mmol/l
0.20
76
357
257
1771
1.55
8.65
1.4
1.3
—
—
—
0
0
217
1441
1.60
8.57
1.9
1.6
—
—
—
0
0
1273
11934
1.82
8.52
7.0
6.2
2.63
2.65
mmol/l
0.46
1192
10999
613
5010
1.40
8.47
5.1
4.2
3.41
0.04
estimate
0.50
148
1168
114
639
1.85
8.32
1.7
2.0
—
—
—
0
0
1057
9514
1.47
8.24
5.3
4.6
14.84
14.90
pmol/l
0.28
985
8690
63
285
2.27
8.23
6.3
7.2
11.90
11.04
mmol/l
0.84
58
261
63
285
2.27
8.23
6.3
7.2
105.98
105.39
mmol/l
0.35
58
261
1310
12412
2.01
8.20
15.9
13.1
26.22
25.16
u/l
1.32
1285
12035
159
989
1.69
8.12
2.5
2.8
—
—
—
0
0
115
652
1.83
8.10
5.4
4.9
1.63
1.56
%
0.33
109
622
1208
11201
1.61
8.01
5.0
4.5
1.36
1.28
mmol/l
3.85
1117
10184
91
487
1.93
7.66
2.3
4.0
102.03
61.70
mg/l
0.33
74
424
107
604
1.84
7.65
5.6
5.1
0.89
0.88
%
0.22
102
574
91
488
1.93
7.62
2.3
4.0
38.96
52.00
mg/l
0.72
73
427
1205
11196
1.58
7.58
6.8
5.6
1.97
1.97
mu/l
0.01
1121
10286
33
113
2.97
7.57
5.8
5.5
212.15
36.82
u/ml
0.45
13
35
153
960
1.67
7.56
1.2
1.2
—
—
—
0
0
1329
12693
2.14
7.56
36.9
27.5
39.66
39.93
%
1.17
1323
12546
1329
12693
2.14
7.56
36.2
27.0
4.41
4.43
e12/l
0.55
1303
12391
1329
12693
2.14
7.56
36.2
26.9
30.18
30.39
pg
4.38
1323
12550
1329
12694
2.14
7.54
36.3
27.1
6.90
6.75
e9/l
1.51
1307
12391
368
2797
1.43
7.51
1.3
1.3
1.53
1.53
u/ml
0.00
80
753
1329
12697
2.13
7.48
36.5
27.2
131.89
133.54
g/l
3.94
1323
12557
182
1196
1.60
7.47
2.8
3.1
66.29
66.42
g/l
0.09
168
1105
330
2463
1.45
7.42
1.5
1.5
2.24
2.52
g/l
2.11
194
1490
41
160
2.61
7.39
1.5
1.4
236.15
325.21
pmol/l
1.41
36
139
1328
12690
2.11
7.37
36.4
27.1
252.57
249.19
e9/l
1.10
1311
12436
1328
12691
2.10
7.35
36.2
27.0
91.08
91.52
fl
3.10
1322
12549
84
444
1.95
7.34
2.2
3.8
5.33
3.01
ratio
0.47
43
262
179
1177
1.60
7.33
3.0
2.5
0.36
0.51
e6/l
0.51
172
1129
170
1107
1.61
7.25
3.0
3.1
157.41
211.45
ng/l
1.05
155
1017
110
649
1.75
6.80
2.3
1.9
1.60
1.53
g/l
0.30
95
577
1237
11623
1.60
6.73
6.3
5.5
6.00
6.00
mmol/l
0.01
1151
10587
216
1511
1.51
6.69
1.8
1.7
—
—
—
0
0
142
907
1.63
6.54
6.4
7.9
24.38
24.93
mmol/l
1.09
142
901
258
1885
1.45
6.42
1.3
1.2
—
—
—
0
0
212
1504
1.48
6.12
3.7
4.2
3.91
20.39
ug/l
2.31
159
1239
656
5615
1.32
5.98
13.8
12.2
0.00
0.00
e9/l
1.88
520
4610
364
2858
1.37
5.95
1.8
1.7
1.78
1.33
mg/l
0.93
290
2230
228
1651
1.46
5.92
3.0
2.8
1.80
1.84
%
0.29
198
1485
183
1270
1.51
5.87
2.6
2.1
0.00
0.02
estimate
0.78
44
241
264
1976
1.41
5.71
2.2
2.1
—
—
—
0
0
36
151
2.42
5.66
1.5
1.5
23.91
33.90
ng/l
0.64
36
151
524
4375
1.32
5.60
3.2
3.2
1991.97
1316.65
ng/l
0.94
451
3788
373
2968
1.35
5.54
5.3
4.4
1.02
1.02
kg/l
1.40
279
2021
508
4233
1.32
5.48
2.5
2.2
153.32
233.08
u/l
2.09
486
4018
174
1214
1.50
5.44
1.9
1.5
—
—
—
0
0
92
553
1.71
5.37
3.1
3.4
2314.09
2826.17
u/ml
0.08
81
480
125
816
1.58
5.29
2.2
2.4
11.46
12.65
nmol/l
0.77
102
717
134
891
1.56
5.24
6.4
6.7
24.06
24.48
mmol/l
0.53
127
852
433
3552
1.32
5.16
2.6
2.3
2.72
2.91
mg/l
0.86
376
3052
198
1433
1.44
5.13
5.7
3.5
7.37
7.38
ph
0.63
123
831
71
406
1.79
4.94
1.5
1.4
255.71
285.49
ug/g
0.47
41
249
221
1648
1.41
4.85
2.0
1.7
—
—
—
0
0
21
73
2.90
4.77
7.2
7.2
104.47
276.21
ug/l
0.31
16
46
115
755
1.57
4.76
3.5
3.6
4.46
4.43
pmol/l
0.11
102
672
75
441
1.74
4.76
1.6
1.6
9.80
14.90
u/ml
0.67
11
74
483
4057
1.29
4.75
1.9
1.7
20.23
20.52
nmol/l
0.16
417
3397
467
3909
1.29
4.71
7.4
6.5
—
—
—
0
0
231
1746
1.39
4.68
1.5
1.3
395.86
542.46
titre
1.49
58
390
137
939
1.51
4.67
4.6
3.7
5.11
5.18
kpa
0.43
132
910
147
1025
1.49
4.62
2.4
3.2
10.20
10.89
g/l
0.99
135
940
194
1429
1.42
4.56
5.6
3.5
5.76
5.81
kpa
0.33
184
1393
82
501
1.68
4.54
2.1
2.8
9.84
10.58
g/l
0.86
75
449
175
1268
1.43
4.51
2.3
2.2
387.46
379.76
nmol/l
0.19
162
1169
202
1502
1.40
4.50
1.4
1.3
—
—
—
0
0
121
819
1.52
4.39
1.7
1.9
1.41
1.47
g/l
0.07
112
753
95
611
1.60
4.31
1.2
1.1
—
1.10
—
0
5
33
152
2.20
4.26
1.3
1.1
—
—
—
0
0
187
1386
1.40
4.25
5.6
3.5
1.25
1.91
mmol/l
1.72
162
1186
182
1343
1.41
4.24
1.8
2.3
0.21
0.21
g/l
0.56
168
1258
132
918
1.48
4.21
4.6
3.8
7.41
7.42
ph
2.18
118
780
41
208
2.00
4.14
1.3
1.4
119.69
157.76
au/ml
—
9
62
143
1018
1.45
4.06
3.1
2.8
6.00
6.06
ph
0.32
86
711
117
802
1.50
4.01
1.5
1.4
—
—
—
0
0
344
2817
1.29
4.01
3.4
3.0
2.47
2.46
mmol/l
0.41
308
2545
102
682
1.53
3.93
4.7
3.8
1.02
1.02
ratio
0.99
91
630
96
637
1.54
3.84
2.3
2.2
0.03
1.35
estimate
0.48
33
186
584
5121
1.24
3.79
4.8
4.1
38.05
69.98
ng/l
1.07
439
3820
44
237
1.88
3.77
1.3
1.4
—
—
—
0
0
444
3780
1.26
3.74
6.6
6.1
2.58
2.91
ug/l
0.37
405
3384
62
374
1.69
3.66
3.4
3.4
3.70
1.90
index
0.89
30
200
207
1610
1.34
3.48
1.4
1.4
—
—
—
0
0
589
5208
1.23
3.44
2.1
2.0
1.40
1.32
mmol/l
1.04
505
4322
101
698
1.48
3.37
2.5
2.5
—
—
—
0
0
170
1294
1.36
3.30
2.9
2.8
68.21
70.48
e9/l
0.44
119
967
152
1137
1.38
3.29
2.6
2.5
4.69
7.19
ug/l
2.41
132
1014
274
2237
1.28
3.22
3.4
3.5
0.95
0.80
ug/l
0.60
192
1527
31
157
2.00
3.21
1.3
1.3
—
—
—
0
0
75
493
1.55
3.17
4.2
4.2
24.13
24.97
mmol/l
1.79
69
459
61
382
1.62
3.16
2.0
1.6
0.22
0.24
g/l
0.63
56
364
49
290
1.71
3.13
1.1
1.1
0.68
4.88
eliau/ml
—
5
30
36
194
1.88
3.13
1.1
1.1
—
—
—
0
0
36
196
1.86
3.04
1.1
1.1
—
—
—
0
0
54
333
1.65
2.98
1.6
2.0
2.68
21.92
iu/l
0.57
20
133
157
1200
1.35
2.98
4.6
3.0
4.91
4.44
kpa
1.81
148
1166
55
343
1.63
2.91
2.1
2.2
136.89
128.70
g/l
1.25
36
278
56
352
1.62
2.88
1.3
1.2
138.00
91.35
titre
—
5
37
283
2351
1.26
2.87
3.5
3.3
0.81
0.82
mmol/l
0.39
265
2225
29
152
1.93
2.76
1.6
1.9
—
—
—
0
0
435
3800
1.21
2.73
4.9
4.3
0.00
0.01
estimate
1.34
166
1320
54
343
1.60
2.68
4.4
4.8
—
—
—
0
0
87
613
1.45
2.68
1.9
1.9
3.47
1.89
ug/l
0.47
75
549
26
133
1.97
2.66
3.3
3.4
13.20
11.79
index
0.39
15
77
17
73
2.34
2.65
1.1
1.1
—
—
—
0
0
40
236
1.72
2.63
1.3
1.4
—
—
—
0
0
116
864
1.37
2.61
1.3
1.3
—
—
—
0
0
205
1657
1.28
2.61
3.3
3.3
5.07
4.66
e9/l
0.18
184
1433
40
237
1.71
2.60
1.3
1.4
—
—
—
0
0
7
15
4.68
2.60
11.3
13.0
5.03
5.41
mmol/l
—
7
15
282
2368
1.24
2.59
1.9
1.7
1051.47
1183.70
nmol/l
1.73
207
1781
11
36
3.07
2.56
1.2
1.6
—
—
—
0
0
11
36
3.07
2.56
1.5
1.2
16.15
6.74
pmol/l
—
6
12
40
238
1.70
2.56
1.4
1.2
—
—
—
0
0
15
62
2.43
2.54
1.3
3.3
530.53
1428.27
u/ml
1.38
15
62
10
31
3.24
2.52
1.3
1.0
14.65
16.87
umol/l
—
10
24
8
21
3.82
2.46
1.0
1.1
—
—
—
0
0
150
1173
1.31
2.46
1.7
1.6
—
—
—
0
0
39
234
1.69
2.44
1.3
1.4
—
—
—
0
0
49
312
1.59
2.43
1.2
1.2
—
—
—
0
0
31
174
1.80
2.43
1.3
1.3
—
—
—
0
0
89
644
1.41
2.40
4.8
4.0
—
—
—
0
0
101
747
1.38
2.39
1.4
1.4
40.95
47.76
au/ml
—
6
60
39
236
1.67
2.37
1.3
1.4
—
—
—
0
0
55
366
1.52
2.28
1.5
1.7
15417.94
12463.84
e6/l
0.17
36
262
23
120
1.93
2.26
1.2
1.1
—
—
—
0
0
109
827
1.34
2.22
2.6
2.5
16.04
21.89
au/ml
—
10
70
381
3350
1.19
2.16
1.3
1.4
—
—
—
0
0
68
480
1.44
2.13
1.1
1.2
—
—
—
0
0
27
153
1.78
2.08
1.4
1.7
—
—
—
0
0
50
333
1.52
2.08
1.2
1.7
—
—
—
0
0
83
612
1.38
2.04
1.3
1.2
—
—
—
0
0
6
15
4.01
2.04
1.0
1.0
—
—
—
0
0
18
90
2.01
2.00
2.3
1.6
135.83
99.24
ng/l
0.89
18
90
35
217
1.63
1.98
1.4
1.4
—
—
—
0
0
5
11
4.56
1.94
1.0
1.2
—
—
—
0
0
259
2220
1.20
1.94
1.3
1.3
5.02
12.96
u/ml
2.83
87
838
6
16
3.76
1.93
1.0
1.0
0.66
0.33
u/ml
—
6
11
28
165
1.71
1.91
2.0
2.5
1.72
1.07
g/24h
0.52
20
99
70
508
1.40
1.90
1.3
1.2
0.32
0.97
u/ml
—
5
35
0
51
0.00
1.89
0.0
1.1
—
—
—
0
0
105
814
1.31
1.88
1.3
1.3
109.66
181.78
u/ml
1.22
98
753
19
101
1.89
1.81
1.4
1.4
—
—
—
0
0
86
652
1.34
1.80
1.7
1.6
—
—
—
0
0
53
370
1.45
1.79
1.4
1.2
1.32
2.45
u/ml
—
6
36
520
4755
1.15
1.74
4.7
3.8
—
0.71
—
0
17
110
870
1.29
1.72
1.4
1.4
—
—
—
0
0
34
219
1.57
1.69
1.1
1.2
265.10
271.74
u/ml
0.05
21
123
0
49
0.00
1.68
0.0
1.2
—
13.59
—
0
37
90
696
1.31
1.67
3.4
3.7
33.41
86.17
u/ml
1.75
85
672
72
539
1.35
1.66
1.9
1.8
8.86
7.89
iu/ml
0.08
16
130
18
98
1.85
1.62
1.3
1.1
38.00
99.29
titre
—
5
14
155
1288
1.23
1.60
6.3
4.5
7.37
7.36
ph
0.60
113
929
16
84
1.91
1.60
1.1
1.9
—
—
—
0
0
15
77
1.96
1.59
1.1
1.1
—
—
—
0
0
270
2370
1.17
1.55
1.4
1.3
48.94
33.24
iu/ml
0.46
79
756
319
2838
1.16
1.54
1.7
1.8
56296734.53
30614431.18
pmol/l
0.27
270
2329
14
72
1.95
1.49
1.8
2.3
227.50
223.70
e6/l
0.03
14
64
13
65
2.01
1.48
1.1
1.0
—
—
—
0
0
67
506
1.34
1.48
1.0
1.1
—
—
—
0
0
52
379
1.39
1.44
1.1
1.1
—
—
—
0
0
50
362
1.40
1.44
4.4
3.3
1.28
1.59
mmol/l
4.10
50
352
26
164
1.60
1.43
1.5
1.7
51.29
60.81
%
0.44
17
107
6
22
2.73
1.43
1.0
1.4
—
—
—
0
0
26
165
1.59
1.40
1.4
1.3
290.86
276.02
mosm/kgh2o
1.18
21
121
21
126
1.68
1.40
1.2
1.2
—
—
—
0
0
45
322
1.41
1.39
2.8
2.3
221.28
81.60
ug/min
0.57
30
185
18
104
1.74
1.37
1.3
1.1
84.50
107.03
pmol/l
1.97
18
104
150
1265
1.21
1.37
4.3
4.6
0.66
0.96
%
0.81
41
408
6
23
2.61
1.37
1.0
1.0
—
—
—
0
0
43
307
1.41
1.35
4.6
3.4
7.71
7.69
mmol/l
0.01
43
298
17
97
1.76
1.35
1.2
1.3
1.70
2.09
mmol/l
2.26
17
91
101
818
1.25
1.35
1.2
1.2
43.34
132.12
u/ml
8.51
30
321
5
18
2.78
1.28
1.8
1.7
—
—
—
0
0
18
107
1.69
1.26
1.3
1.2
—
—
—
0
0
8
37
2.17
1.21
2.0
1.8
65.75
85.65
nmol/24h
—
8
37
6
26
2.31
1.18
1.5
2.2
0.15
0.19
e9/l
—
6
8
6
26
2.31
1.18
1.5
1.3
—
—
—
0
0
31
214
1.46
1.18
1.3
1.9
637.08
2736.92
u/l
—
5
81
7
138
0.50
1.10
1.4
1.2
—
—
—
0
0
5
21
2.39
1.09
1.6
2.6
21.18
18.69
umol/l
—
5
21
306
2781
1.13
1.09
5.8
5.0
—
—
—
0
0
36
261
1.39
1.08
1.4
1.5
0.91
0.86
nmol/l
0.12
31
214
13
74
1.76
1.06
1.2
1.7
—
—
—
0
0
39
288
1.36
1.05
1.4
1.3
425.25
220.88
miu/ml
—
8
121
140
1206
1.18
1.05
4.7
4.9
0.12
0.12
%
0.00
33
313
23
154
1.50
1.04
1.4
1.7
—
—
—
0
0
16
98
1.64
1.03
1.4
1.3
—
—
—
0
0
17
106
1.61
1.03
1.5
1.2
15.53
11.07
u/l
0.43
17
96
20
130
1.55
1.03
1.1
1.2
—
—
—
0
0
9
47
1.92
1.02
1.2
1.4
5.09
3.57
mmol/l
—
9
42
34
247
1.39
1.02
1.5
1.3
4.93
11.52
u/l
8.01
22
194
78
640
1.23
0.98
1.3
1.2
—
—
—
0
0
139
1205
1.17
0.98
4.5
4.7
0.06
0.11
%
0.50
31
346
18
116
1.56
0.96
1.2
1.4
2.57
2.89
g/l
0.36
13
84
18
116
1.56
0.96
1.2
1.4
0.27
0.38
g/l
1.55
12
83
18
116
1.56
0.96
1.2
1.4
6.29
7.04
g/l
0.40
13
85
138
1202
1.16
0.92
4.4
4.5
0.49
0.67
%
0.47
35
376
24
167
1.44
0.92
2.2
7.0
6.74
7.44
mmol/l
0.45
19
137
6
28
2.15
0.91
5.5
7.1
10.32
5.19
kpa
—
6
28
18
118
1.53
0.91
1.2
1.4
—
—
—
0
0
34
253
1.35
0.90
1.7
1.7
—
—
—
0
0
14
87
1.62
0.87
2.1
1.6
260.56
320.80
mu/l
—
9
66
6
30
2.00
0.87
1.3
1.1
—
—
—
0
0
20
136
1.48
0.86
1.5
1.5
—
—
—
0
0
8
44
1.82
0.86
1.6
1.2
142.25
168.98
pmol/l
—
8
44
17
112
1.52
0.85
2.2
1.9
2.00
1.78
u/field
0.12
12
64
143
1259
1.15
0.84
1.6
1.6
—
—
—
0
0
16
104
1.54
0.84
2.6
2.2
760.18
623.84
ml
0.42
11
63
6
31
1.94
0.84
1.3
2.0
—
—
—
0
0
6
31
1.94
0.84
1.3
1.4
6.37
8.06
mmol/l
—
6
31
45
356
1.27
0.80
1.2
1.1
—
—
—
0
0
6
33
1.82
0.79
1.2
1.3
22.67
26.36
%
—
6
25
6
33
1.82
0.79
3.5
4.0
—
—
—
0
0
58
475
1.23
0.78
1.7
1.6
0.31
0.35
mg/l
0.26
16
214
39
305
1.29
0.77
5.6
3.8
—
—
—
0
0
24
174
1.39
0.77
1.3
1.2
3.93
5.44
u/ml
0.33
14
79
14
91
1.54
0.75
1.6
2.7
16.06
16.36
%
0.09
14
91
22
158
1.40
0.74
1.3
1.4
74992.54
67050.29
e6/l
0.06
13
86
16
108
1.49
0.73
1.1
1.1
—
83.87
—
0
6
9
55
1.64
0.73
1.0
1.1
—
—
—
0
0
9
55
1.64
0.73
1.2
1.4
156.33
174.10
mmol/24h
—
9
55
9
56
1.61
0.72
1.3
1.1
1182.44
1678.04
miu/ml
—
9
56
21
151
1.40
0.71
2.0
2.6
—
—
—
0
0
15
101
1.49
0.70
1.1
1.1
—
—
—
0
0
9
58
1.55
0.69
3.2
3.3
—
—
—
0
0
40
319
1.26
0.69
3.7
2.8
90.70
89.35
%
0.80
40
308
7
42
1.67
0.68
1.6
2.6
0.63
0.62
mmol/l
—
7
42
21
153
1.38
0.67
1.6
2.1
—
—
—
0
0
14
94
1.49
0.66
1.1
1.1
—
—
—
0
0
24
180
1.34
0.65
1.5
1.4
5564.88
1676.57
e6/l
0.80
17
124
8
128
0.62
0.64
2.9
2.5
—
—
—
0
0
83
721
1.16
0.63
2.0
1.8
3.28
3.51
mmol/l
1.17
58
527
124
1109
1.13
0.62
5.9
3.8
1.24
1.23
mmol/l
1.16
113
955
10
63
1.59
0.61
2.7
2.6
—
—
—
0
0
8
51
1.57
0.60
3.5
3.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
0.02
—
0
20
0
21
0.00
0.60
0.0
1.0
—
23.52
—
0
14
25
192
1.31
0.59
1.0
1.1
14.58
24.01
au/ml
—
5
48
18
131
1.38
0.59
1.3
1.4
19.08
30.39
u/l
0.91
13
109
16
114
1.41
0.59
1.1
1.2
—
—
—
0
0
10
64
1.57
0.58
1.1
1.2
111.60
440.49
u/l
—
10
59
42
346
1.22
0.58
1.2
1.3
—
—
—
0
0
6
35
1.72
0.57
2.8
3.0
3.17
6.11
ug/l
—
6
35
6
35
1.72
0.57
1.5
1.3
25.00
28.57
s
—
6
35
6
36
1.67
0.56
1.3
1.1
—
—
—
0
0
10
65
1.54
0.55
1.5
1.4
—
4.69
%
—
0
13
6
39
1.54
0.53
1.8
2.4
170.67
142.76
nmol/l
—
6
34
42
351
1.20
0.52
1.1
1.2
—
—
—
0
0
11
75
1.47
0.50
1.5
1.3
123.55
139.46
nmol/l
0.82
11
75
58
503
1.16
0.48
1.3
1.7
—
—
—
0
0
46
392
1.18
0.47
3.9
4.0
3.87
3.91
mmol/l
0.24
46
386
7
49
1.43
0.46
1.1
1.1
89.00
229.78
iu/ml
—
7
49
54
470
1.15
0.44
1.5
1.4
41.63
32.10
iu/l
0.99
49
399
31
372
0.83
0.44
8.9
11.5
—
—
—
0
0
25
203
1.24
0.42
1.6
1.7
0.73
0.88
g/l
0.19
20
160
10
139
0.72
0.42
1.0
1.3
—
—
—
0
0
33
277
1.20
0.41
6.3
4.6
8.75
8.33
kpa
0.78
33
272
0
17
0.00
0.40
0.0
1.5
—
46.35
—
0
17
0
17
0.00
0.40
0.0
1.1
—
875.68
—
0
5
35
296
1.19
0.40
2.9
3.2
63.20
58.93
%
1.43
35
296
7
106
0.66
0.39
2.6
2.3
13.14
13.18
%
—
7
106
52
457
1.14
0.38
5.6
3.7
7.41
7.41
ph
0.25
52
452
32
270
1.19
0.38
1.2
1.4
—
—
—
0
0
175
1641
1.08
0.38
5.8
5.1
31.23
32.72
%
0.95
118
1068
16
125
1.28
0.37
2.5
2.3
—
—
—
0
0
18
143
1.26
0.37
1.2
1.3
515904.00
172120.58
e6/l
—
7
93
84
764
1.11
0.36
1.4
1.4
—
—
—
0
0
9
71
1.27
0.36
1.2
1.2
—
—
—
0
0
34
291
1.17
0.36
1.1
1.2
—
—
—
0
0
28
236
1.19
0.35
3.4
3.3
4.48
4.35
e9/l
0.15
28
236
94
1022
0.91
0.35
5.4
4.1
—
—
—
0
0
108
1000
1.09
0.33
2.3
2.1
3.39
3.45
ratio
0.21
78
805
32
275
1.17
0.33
6.2
4.5
2.77
2.75
mmol/l
0.02
24
190
32
276
1.16
0.32
6.2
4.5
5.03
5.07
kpa
0.09
32
271
11
84
1.31
0.30
2.2
2.2
2.69
3.30
ug/l
0.33
11
79
19
157
1.21
0.29
1.5
1.5
—
—
—
0
0
31
269
1.16
0.29
1.1
1.2
—
—
—
0
0
7
57
1.23
0.29
1.3
1.8
41.64
39.41
g/l
—
7
57
14
172
0.81
0.27
1.1
1.3
—
—
—
0
0
20
168
1.19
0.27
1.4
1.2
—
—
—
0
0
17
141
1.21
0.26
1.1
1.4
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
—
14.17
%
—
0
6
12
97
1.24
0.23
1.9
1.6
45.83
38.75
%
0.53
12
97
18
153
1.18
0.22
1.2
1.4
—
—
—
0
0
33
295
1.12
0.22
1.1
1.3
3.35
62.00
e6/l
1.33
26
220
28
315
0.89
0.21
1.6
1.2
0.90
0.92
g/l
0.17
28
315
0
11
0.00
0.21
0.0
1.8
—
1.42
—
0
6
0
12
0.00
0.21
0.0
1.0
—
5.52
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
7.57
—
0
7
8
101
0.79
0.21
1.1
1.1
28.96
36.47
mmol/l
—
8
91
8
102
0.78
0.21
1.0
1.4
—
—
—
0
0
14
166
0.84
0.20
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
9.00
—
0
6
6
48
1.25
0.20
2.2
1.4
35.00
32.31
%
—
6
48
6
48
1.25
0.20
1.0
1.2
14.67
9.83
mm/h
—
6
48
6
48
1.25
0.20
2.0
1.5
1.98
1.94
umol/l
—
6
39
15
127
1.18
0.19
1.1
1.1
—
—
—
0
0
81
763
1.07
0.19
4.6
2.7
1.03
1.17
%
0.96
81
757
7
58
1.21
0.18
1.1
1.1
1.12
1.06
ratio
—
7
50
12
100
1.20
0.18
1.2
1.1
0.43
4.24
nmol/l
—
5
19
31
281
1.11
0.17
1.4
1.3
63.44
59.38
mmol/l
0.18
25
224
24
268
0.89
0.17
3.4
4.0
31.56
26.86
mg/l
0.26
17
188
15
129
1.16
0.17
1.2
1.2
2.55
1.38
nmol/l
—
10
111
8
68
1.18
0.16
2.1
1.4
—
—
—
0
0
26
235
1.11
0.15
1.0
1.5
—
9.43
—
0
6
24
216
1.11
0.15
1.7
2.2
0.94
0.91
%
0.09
17
155
9
79
1.14
0.15
1.7
1.7
80.78
81.04
umol/l
—
9
79
14
121
1.16
0.15
1.1
1.0
1.85
2.39
u/ml
—
7
54
79
752
1.05
0.15
4.6
2.6
0.62
0.62
%
0.00
79
746
13
150
0.87
0.14
1.0
1.1
2.53
3.61
u/ml
—
8
74
9
83
1.08
0.14
1.7
1.6
—
—
—
0
0
20
179
1.12
0.14
1.4
1.5
—
—
—
0
0
20
179
1.12
0.14
1.4
1.5
—
—
—
0
0
20
179
1.12
0.14
1.4
1.5
—
—
—
0
0
20
179
1.12
0.14
1.4
1.5
—
—
—
0
0
19
212
0.89
0.14
2.2
2.7
—
—
—
0
0
14
122
1.15
0.13
1.5
1.5
34.32
31.01
%
—
8
79
12
103
1.17
0.13
1.4
2.4
9.44
8.67
mmol/l
0.13
12
103
21
231
0.91
0.12
2.3
1.9
1.42
1.64
mmol/l
0.83
21
224
19
173
1.10
0.10
1.6
1.7
—
—
—
0
0
14
156
0.90
0.10
1.0
1.1
—
—
—
0
0
18
197
0.91
0.10
2.5
2.7
—
—
—
0
0
25
268
0.93
0.09
1.4
1.1
0.60
0.70
ratio
—
8
39
28
298
0.94
0.08
1.6
1.2
1.59
1.58
g/l
0.03
28
298
10
113
0.88
0.08
1.5
1.2
0.32
0.89
u/ml
—
5
55
7
65
1.08
0.08
1.3
1.4
23.29
29.90
umol/l
—
7
58
15
164
0.91
0.08
1.1
1.1
—
—
—
0
0
8
74
1.08
0.07
1.0
1.0
—
—
—
0
0
15
137
1.10
0.07
2.2
2.1
—
—
—
0
0
12
108
1.11
0.07
1.1
1.1
—
—
—
0
0
16
148
1.08
0.06
1.0
1.1
0.77
2.13
eliau/ml
—
7
57
436
4340
1.01
0.03
3.6
3.4
—
—
—
0
0
15
142
1.06
0.02
1.1
1.0
0.53
0.94
u/ml
—
9
73
31
301
1.03
0.02
3.6
2.6
16.87
16.21
%
0.48
31
294
10
106
0.94
0.01
1.0
1.0
0.01
0.24
u/ml
—
5
37
16
155
1.03
0.00
1.1
1.2
—
—
—
0
0
18
181
0.99
0.00
1.1
1.1
0.51
2.01
u/ml
1.46
13
103
14
137
1.02
0.00
1.0
1.5
—
—
—
0
0
33
332
0.99
0.00
1.2
1.3
435.58
542.64
mg/l
1.98
33
318
12
118
1.02
0.00
1.1
1.1
1.28
3.20
u/ml
—
5
47
15
148
1.01
0.00
3.3
4.5
—
—
—
0
0
17
168
1.01
0.00
1.1
1.2
—
—
—
0
0
11
112
0.98
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.6
—
15.50
—
0
8
0
8
0.00
0.00
0.0
6.9
—
0.15
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
364.80
—
0
5
8
81
0.99
-0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
3.74
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
487.01
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
33.51
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
63.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
0
5
0.00
-0.00
0.0
19.8
—
142.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
0.05
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_KIDNEY and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_KIDNEY 1.198 [1.05, 1.36] 0.005
Birth year 0.993 [0.98, 1.0] 0.122

During the follow-up period (1.1.1998 — 31.12.2019), 525 out of 3055 females with CD2_BENIGN_KIDNEY died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_KIDNEY 1.35 [1.17, 1.56] < 0.001
Birth year 0.99 [0.98, 1.0] 0.041

During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 1946 males with CD2_BENIGN_KIDNEY died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_KIDNEY.

N-year risk Females Males
1 0.095% 0.245%
5 0.589% 1.509%
10 1.686% 4.136%
15 3.282% 7.802%
20 5.995% 13.486%

Relationships between endpoints

Index endpoint: CD2_BENIGN_KIDNEY – Benign neoplasm: Kidney

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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