Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3046426	s-aqp4ab	— (—)	824	949	100.00%	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Other degenerative diseases of the nervous system

448

98.73

307.65

1.2

1.1

—

Autoimmune diseases related-to ILD

470

336

11.77

307.65

1.2

1.1

—

MS-disease / Multiple Sclerosis

388

122.52

307.65

1.2

1.1

—

Demyelinating diseases of the central nervous system

444

125.54

307.65

1.2

1.1

—

Other demyelinating diseases of the central nervous system

225

219.12

307.65

1.2

1.1

—

Disorders of optic nerve and visual pathways

361

96.20

307.65

1.3

1.0

—

Optic neuritis

280

277.92

307.65

1.3

1.0

—

Autoimmune diseases excluding thyroid diseases

456

221

11.24

300.78

1.1

—

Autoimmune diseases excluding thyroid diseases, strict definition

442

216

11.19

291.56

1.1

—

ILD medications: immunosuppressive drugs

336

311

9.86

277.49

1.2

1.1

—

Visual disturbances and blindness

296

298

10.01

259.72

1.2

1.1

—

Visual disturbances

276

294

9.47

232.69

1.2

1.1

—

Other disorders of optic [2nd] nerve and visual pathways

121

74.48

224.54

1.1

1.0

—

Autoimmune diseases

381

223

8.71

208.30

1.2

1.1

—

Neurological diseases

298

108

13.92

206.16

1.1

—

Used for control exclusion in common control thyroid runs

345

202

8.64

187.09

1.2

1.1

—

L04AA Selective immunosuppressants

171

168

10.33

153.18

1.2

1.1

—

ILD medications

379

367

5.59

152.69

1.2

1.1

—

Disturbances of skin sensation

201

246

8.27

152.16

1.2

1.1

—

Subjective visual disturbances

159

149

10.79

147.11

1.2

1.1

—

Diseases of the eye and adnexa

264

170

7.81

133.63

1.1

—

Encephalitis

60.61

132.28

1.5

1.0

—

Other encephalitis

68.85

129.70

1.5

1.0

—

Inflammatory diseases of the central nervous system

19.55

110.41

1.4

1.0

—

Abnormal findings on diagnostic imaging of central nervous system

24.58

106.88

1.1

—

Neurological diseases, wide definition

126

25.45

106.27

1.1

—

Symptoms and signs involving the skin and subcutaneous tissue

242

494

4.64

101.14

1.2

1.1

—

Symptoms and signs involving the nervous and musculoskeletal systems

203

387

5.27

100.20

1.1

1.2

—

Ocular pain

14.22

93.03

1.5

1.0

—

Use of interferon beta-1a

35.75

90.03

1.3

1.1

—

Other and unspecified visual disturbances

16.46

86.55

1.2

1.1

—

L04AX Other immunosuppressants

193

404

4.80

85.51

1.2

1.1

—

Second line medication for Crohn's disease

196

424

4.64

83.39

1.2

1.1

—

Other disorders of eye and adnexa

101

114

8.98

81.70

1.5

1.0

—

Other symptoms and signs involving the nervous and musculoskeletal systems

161

306

5.29

79.90

1.1

1.2

—

Visual impairment including blindness (binocular or monocular)

31.10

74.83

1.2

1.0

—

Neuromuscular dysfunction of bladder

15.47

63.15

1.3

1.1

—

Papilloedema, unspecified

141.89

62.74

1.2

1.0

—

Postprocedural disorders of nervous system

9.53

59.91

1.3

1.1

—

Diplopia

11.70

56.71

1.2

1.1

—

ILD medications: prednisolone, methylprednisolone, prednisone

225

349

3.59

56.23

1.2

1.1

—

Headache

195

435

3.47

52.12

1.2

1.1

—

Concussion

7.15

49.45

1.2

1.1

—

Other neurological diseases

159

331

3.73

47.31

1.2

1.1

—

Use of teriflunomide

97.08

47.07

1.2

1.0

—

Intracranial trauma

6.69

46.94

1.2

1.1

—

Any reimbursement code in KELA

177

231

3.85

46.62

1.1

—

Visual field defects

16.52

42.69

1.1

—

Abnormalities of gait and mobility

11.59

36.92

1.2

1.1

—

Cerebral palsy and other paralytic syndromes

7.49

36.44

1.2

1.1

—

Use of fingolimod

59.41

36.31

1.2

1.0

—

Hypothyroidism, strict autoimmune

107

171

4.11

34.30

1.2

1.1

—

Use of glatiramer acetate

44.66

31.22

1.2

1.0

—

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

123

340

3.15

29.52

1.1

—

Other soft tissue disorders, not elsewhere classified

207

473

2.49

28.75

1.2

1.1

—

Pain, not elsewhere classified

212

3.83

27.20

1.2

1.1

—

Pain in joint

118

222

3.27

27.07

1.2

1.1

—

Other special examinations and investigations of persons without complaint or reported diagnosis

131

216

3.08

25.56

1.1

—

Migraine

146

435

2.62

24.45

1.2

—

Optic atrophy

58.27

24.20

1.4

1.0

—

Other dorsopathies, not elsewhere classified

205

463

2.30

23.55

1.1

—

Other diseases of urinary system

190

457

2.34

23.08

1.1

—

General symptoms and signs

207

455

2.28

23.06

1.2

1.1

—

Pain in limb

174

463

2.39

23.01

1.2

1.1

—

Dorsalgia

199

459

2.30

22.96

1.1

—

Medical observation and evaluation for suspected diseases and conditions

124

216

2.94

22.60

1.1

—

Other and unspecified polyneuropathies, also in other diseases

6.02

22.44

1.1

1.0

—

Polyneuropathies and other disorders of the peripheral nervous system

5.19

22.15

1.1

1.0

—

Dorsopathies

203

463

2.22

21.43

1.2

1.1

—

Other disorders of bladder

7.47

20.35

1.2

1.1

—

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

4.02

20.31

1.1

—

Disorders of ocular muscles, binocular movement, accommodation and refraction

121

476

2.53

20.01

1.2

—

First line medication for Crohn's disease

211

544

2.09

19.55

1.2

1.1

—

Symptoms and signs involving the urinary system

130

396

2.48

19.49

1.1

—

Other diseases of spinal cord

26.52

19.17

1.1

1.0

—

Other disorders of lacrimal gland

276

2.98

18.68

1.3

1.2

—

Cystitis

160

420

2.27

18.61

1.1

—

Polyuria

107

4.31

18.21

1.2

1.0

—

Depression

185

598

2.07

17.77

1.2

1.1

—

Use of amantadine

37.88

17.71

1.1

1.0

—

Dizziness and giddiness

134

449

2.32

17.64

1.2

1.1

—

Low back pain

147

443

2.24

17.26

1.1

—

Disorders of lacrimal system

327

2.71

17.24

1.2

1.1

—

Episodal and paroxysmal disorders

202

505

2.03

17.20

1.2

—

Examination and observation for other reasons

103

214

2.72

17.11

1.1

—

General examination and investigation of persons without complaint and reported diagnosis

110

216

2.65

16.94

1.2

1.1

—

Disorders of thyroid, IBD co-morbidities

9.68

16.94

1.3

1.1

—

Retention of urine

114

3.77

16.49

1.1

—

Soft tissue disorders

191

481

2.04

16.44

1.2

1.1

—

Mood disorders, excluding more controls

167

465

2.11

16.41

1.2

1.1

—

Mood [affective] disorders

187

602

1.99

16.08

1.2

1.1

—

Diseases of the musculoskeletal system and connective tissue

122

250

2.45

16.03

1.1

—

Mood disorders

187

602

1.99

16.00

1.2

1.1

—

Anxiety disorders, excluding more controls

153

456

2.15

15.98

1.2

1.1

—

Other headache syndromes

365

2.54

15.76

1.2

—

Anxiety disorders

171

582

2.02

15.50

1.2

1.1

—

ILD medications: azathioprine

4.68

15.37

1.4

1.1

—

Pain (limb, back, neck, head abdominally)

112

226

2.49

15.17

1.1

—

Symptoms and signs involving cognition, perception, emotional state and behaviour

169

566

2.00

14.83

1.2

1.1

—

Lower back pain or/and sciatica

190

616

1.92

14.65

1.1

1.2

—

Neurotic, stress-related and somatoform disorders

168

585

1.98

14.52

1.2

—

Chorioretinal inflammation

22.58

14.24

1.1

1.0

—

Malaise and fatigue

266

2.55

13.94

1.2

1.1

—

Other antidepressants

167

426

2.00

13.85

1.2

1.1

—

Migraine without aura

256

2.74

13.83

1.2

1.1

—

Other specific joint derangements/joint disorders

155

480

2.01

13.75

1.1

—

Other joint disorders

182

492

1.93

13.73

1.2

1.1

—

Iridocyclitis

171

3.11

13.12

1.2

1.1

—

Diseases of the myoneural junction and muscle

5.02

12.40

1.3

1.1

—

Any gastric operation

153

387

1.99

12.40

1.1

1.2

—

GASTRO-related operations

153

387

1.99

12.40

1.1

1.2

—

Systemic connective tissue disorders

233

2.71

12.22

1.2

1.1

—

Other symptoms and signs involving the urinary system

5.50

12.10

1.0

—

Opioids

179

504

1.84

11.67

1.2

1.1

—

Care involving use of rehabilitation procedures

107

458

2.10

11.60

1.1

—

Symptoms and signs involving the digestive system and abdomen

156

409

1.91

11.43

1.1

—

Oral corticosteroids

175

567

1.81

11.30

1.2

1.1

—

Provisional assignment of new diseases of uncertain etiology

102

484

2.09

11.13

1.3

1.1

—

Sciatica+with lumbago

332

2.27

11.10

1.1

—

Codes for special purposes

102

485

2.09

11.07

1.3

1.1

—

Abdominal and pelvic pain

154

409

1.89

10.97

1.1

—

Other disorders of urethra and urinary system

116

398

2.03

10.90

1.2

1.1

—

Myalgia

214

2.67

10.80

1.2

1.1

—

Inflammatory bowel disease treatment related agents

190

606

1.74

10.65

1.2

1.1

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

302

2.36

10.52

1.2

1.1

—

Persons encountering health services for examination and investigation

216

2.23

10.49

1.1

—

Other intervertebral disc disorders

126

383

1.96

10.44

1.1

—

Acute upper respiratory infections of multiple and unspecified sites

138

539

1.87

10.37

1.2

1.1

—

Any mental disorder

168

467

1.80

10.34

1.1

—

Dementia in other diseases classified elsewhere

23.49

10.24

1.6

1.0

—

Tramadol

129

404

1.92

10.10

1.2

1.1

—

Asthma (mode)

130

353

1.94

10.06

1.1

—

Acute upper respiratory infections

166

564

1.76

9.97

1.2

1.1

—

Depression medications

152

2.45

9.93

1.1

—

Strabismus

247

2.47

9.88

1.1

—

Anterior Iridocyclitis

151

2.92

9.88

1.1

—

Anxiety (asthma-related co-morbidities)

124

498

1.89

9.82

1.2

1.1

—

Lumbar disc prolapse

347

2.07

9.82

1.1

—

Asthma

129

348

1.91

9.63

1.1

—

Paralytic strabismus

8.38

9.54

1.1

1.0

—

Other and unspecified iridocyclitis

10.08

9.51

1.4

1.1

—

Follow-up examination after treatment for conditions other than malignant neoplasms

193

2.38

9.49

1.3

1.1

—

Disorders of choroid and retina

105

369

1.99

9.48

1.2

1.1

—

Diseases of the ear and mastoid process

192

573

1.68

9.35

1.2

1.1

—

Retinal detachments and breaks

146

2.88

9.24

1.2

1.1

—

Asthma, excluding more controls

126

342

1.89

9.13

1.1

—

Arthropathies

168

492

1.73

9.05

1.2

1.1

—

All anxiety disorders

128

549

1.81

8.89

1.2

1.1

—

Acute and subacute iridocyclitis

140

2.87

8.72

1.1

—

Codeine

158

496

1.72

8.61

1.2

1.1

—

Special screening examination for infectious and parasitic diseases

171

2.44

8.45

1.2

1.1

—

Azathioprine

116

3.03

8.40

1.4

1.1

—

Mild or no visual impairment, binocular

+∞

8.39

1.0

0.0

—

Disorders of sclera, cornea, iris and ciliary body

480

1.94

8.38

1.1

—

Urinary track infection

121

326

1.86

8.33

1.1

—

Other symptoms and signs involving cognitive functions and awareness

203

2.40

8.30

1.1

—

Other reaction to severe stress, and adjustment disorders

442

1.97

8.20

1.2

1.1

—

Other systemic involvement of connective tissue (FG)

153

2.70

8.19

1.3

1.1

—

Bronchitis

173

631

1.64

8.18

1.2

1.1

—

Recurrent or chronic depression

235

2.16

8.14

1.2

1.1

—

Benign intracranial hypertension

17.60

8.12

1.0

—

Abnormal involuntary movements

3.57

8.11

1.0

1.1

—

Disorders of eyelid, lacrimal system and orbit

129

538

1.76

8.08

1.2

1.1

—

Persons encountering health services for other counselling and medical advice, not elsewhere classified

168

537

1.66

8.07

1.2

1.1

—

Other/unspecified dorsalgia

263

2.26

8.03

1.2

1.1

—

Other necrotizing vasculopathies (FG)

10.05

8.02

1.0

—

Disorders of vitreous body and globe

235

2.30

7.88

1.3

1.1

—

Sixth [abducent] nerve palsy

13.11

7.88

1.0

—

Diarrhoea and gastroenteritis of presumed infectious origin, including avohilmo

156

602

1.66

7.81

1.2

1.1

—

Nausea and vomiting

185

2.48

7.76

1.2

1.1

—

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

3.88

7.69

1.0

1.1

—

Asthma, unspecified (mode)

315

1.97

7.68

1.2

1.1

—

COPD/asthma related infections

162

489

1.66

7.65

1.2

1.1

—

COPD/asthma/ILD related infections

162

489

1.66

7.65

1.2

1.1

—

Hypothyroidism, levothyroxine purchases

144

2.34

7.65

1.1

—

Hypothyroidism and >3 levothyroxin purchases

144

2.34

7.65

1.1

—

Viral infections characterized by skin and mucous membrane lesions, including avohilmo

144

672

1.67

7.60

1.2

—

Other necrotizing vasculopathies

8.04

7.59

1.0

—

Disorders of vitreous body

229

2.29

7.56

1.3

1.1

—

Codeine or tramadol medication

177

598

1.61

7.54

1.2

1.1

—

Asthma, unspecified (mode), excluding more controls

310

1.96

7.50

1.2

1.1

—

Disorders of refraction and accommodation

293

2.15

7.50

1.3

1.1

—

Parasetamol

124

353

1.78

7.46

1.1

—

Genitourinary diseases

232

1.97

7.43

1.1

—

Acetic acid derivatives and related substances

2.92

7.38

1.2

—

Enlarged lymph nodes

104

2.99

7.32

1.1

—

Other and unspecified disorders of vitreous body

174

2.47

7.26

1.3

1.1

—

Hypothyroidism (congenital or acquired)

144

2.30

7.25

1.1

—

ILD differential diagnosis

124

353

1.76

7.24

1.1

—

Radiculopathy

3.83

7.24

1.0

1.1

—

COPD differential diagnosis

124

354

1.76

7.18

1.1

—

Other disorders of central nervous system

20.37

7.16

1.4

1.0

—

Persons encountering health services in other circumstances, wide

168

537

1.61

7.11

1.2

1.1

—

Asthma (only as main-diagnosis), excluding more controls

111

342

1.80

7.09

1.2

1.1

—

Trigeminal neuralgia

6.03

7.07

1.1

—

Symptoms and signs involving the circulatory and respiratory systems

170

532

1.60

7.04

1.2

1.1

—

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

364

1.98

6.97

1.2

1.1

—

Asthma (only as main-diagnosis)

111

348

1.78

6.97

1.2

1.1

—

Dysphagia

130

2.70

6.90

1.2

1.1

—

SLE (Finngen)

16.77

6.75

1.8

1.2

—

168

537

1.59

6.72

1.2

1.1

—

Depression or dysthymia

253

1.90

6.70

1.1

—

Coxibs

2.77

6.63

1.1

1.2

—

Excluding asthma or asthma-COPD overlap

121

352

1.72

6.61

1.1

—

Other pulmonary diagnosis

121

352

1.72

6.61

1.1

—

Other specified/unspecified dorsopathies

12.30

6.58

1.0

—

Other complications of surgical and medical care, not elsewhere classified

3.57

6.58

1.0

—

Disorders of vestibular function (Vertigo)

283

2.07

6.52

1.2

1.1

—

Other functional intestinal disorders

306

1.99

6.50

1.2

1.1

—

Gastrointestinal diseases

112

321

1.75

6.46

1.1

—

Other and unspecified drugs and medicaments

3.74

6.36

1.1

—

Thyroiditis, ILD-related definition

3.74

6.35

1.3

1.1

—

Nerve, nerve root and plexus disorders

155

591

1.58

6.29

1.1

—

Other systemic involvement of connective tissue

193

2.28

6.16

1.3

1.1

—

Other local infections of skin and subcutaneous tissue

3.21

6.13

1.2

1.1

—

Anaemias

135

2.28

6.09

1.1

—

Giant cell arteritis

12.57

6.08

1.0

—

Viral hepatitis, IBD co-morbidity

12.54

6.08

1.1

—

Covid-19 suspected case

247

2.11

6.01

1.4

1.1

—

Certain infectious and parasitic diseases

146

460

1.59

5.95

1.2

1.1

—

Migraine without aura and triptan purchases

242

2.11

5.92

1.2

1.1

—

Implicit viral Sepsis, including avohilmo

196

2.24

5.92

1.2

1.1

—

Temporal arteritis

15.08

5.90

1.0

—

Giant cell arteritis with polymyalgia rheumatica

15.08

5.90

1.0

—

Migraine with aura

291

2.00

5.80

1.2

1.1

—

Other external causes of accidental injury

127

391

1.63

5.70

1.1

1.2

—

Selective serotonin reuptake inhibitors

132

427

1.61

5.69

1.2

1.1

—

Faecal incontinence

5.57

5.67

1.3

1.0

—

Diseases of inner ear

327

1.90

5.64

1.3

1.1

—

Fibromyalgia

3.04

5.64

1.1

—

Other general symptoms and signs

5.53

5.63

1.2

1.1

—

Triptan medication for migraine, single purchase ok

132

566

1.58

5.61

1.2

1.1

—

Migraine, single triptan purchase ok & required. ICD-code if available is included

132

566

1.58

5.61

1.2

1.1

—

Other and unspecified local infections of skin and subcutaneous tissue

3.19

5.58

1.1

—

Metatarsalgia

3.29

5.57

1.2

1.1

—

Somatoform disorder

146

2.40

5.52

1.2

1.1

—

Intestinal infectious diseases, including avohilmo, including avohilmo

161

591

1.52

5.52

1.2

1.1

—

Other nutritional deficiencies

110

623

1.61

5.38

1.1

—

Dental pulpitis, including avohilmo

150

632

1.52

5.35

1.1

1.2

—

Parkinson's disease, strict definition, excluding more controls

12.00

5.34

1.1

1.0

—

Mycoses, including avohilmo

138

684

1.54

5.32

1.2

1.1

—

Asthma-related infections

505

1.70

5.31

1.2

—

Asthma, hospital admission 2, infections

505

1.70

5.31

1.2

—

Parkinson's disease, excluding more controls

11.84

5.30

1.1

1.0

—

11.34

5.29

1.0

—

Pain in throat and chest

132

501

1.56

5.21

1.1

—

Implicit Sepsis

412

1.68

5.21

1.2

—

Motor neuron disease (with DMD)

+∞

5.21

1.2

0.0

—

Disorders of conjunctiva

131

657

1.54

5.21

1.2

—

Other enthesopathy of foot (+metatarsalgia)

3.05

5.21

1.1

—

Asthma, including avohilmo

171

637

1.48

5.20

1.1

—

Asthma (diagnoses ohter than nonallergic)

129

674

1.55

5.18

1.2

1.1

—

Spondyloarthritis

2.88

5.18

1.2

1.1

—

Implicit viral Sepsis

115

2.53

5.11

1.0

1.1

—

Viral Sepsis

115

2.53

5.11

1.0

1.1

—

Acute sinusitis

503

1.66

5.09

1.2

1.1

—

Myopia

152

2.31

5.08

1.3

1.1

—

Chronic diseases of tonsils and adenoids

121

484

1.58

5.08

1.1

1.2

—

Moderate visual impairment, binocular

13.40

5.08

1.4

1.0

—

Hemiplegia

6.34

5.07

1.1

—

Chronic iridocyclitis

5.68

5.06

1.1

—

Systemic atrophies primarily affecting the central nervous system

8.37

5.06

1.1

1.0

—

Fungal Sepsis

8.37

5.06

1.4

1.0

—

Hypothyroidism, other/unspecified

131

558

1.54

5.06

1.2

1.1

—

Other anxiety disorders

498

1.64

5.00

1.1

—

Infections, IBD-co-morbidities

6.10

4.98

1.2

1.1

—

Syncope and collapse

220

1.97

4.95

1.3

1.1

—

Accidents

123

391

1.58

4.92

1.1

1.2

—

Cerebral cysts

3.67

4.92

1.0

—

Spirochaetal infections, other/unspecified

3.67

4.92

1.1

1.0

—

Cluster headache, strict

5.45

4.91

1.2

1.0

—

430

1.73

4.89

1.2

1.1

—

Soft tissue disorders related to use, overuse and pressure

143

2.31

4.82

1.2

1.1

—

Diseases of the skin and subcutaneous tissue

143

474

1.51

4.81

1.1

—

Endocrine, nutritional and metabolic diseases

138

457

1.53

4.80

1.1

—

Implicit fungal Sepsis, including avohilmo

4.84

4.80

1.1

—

Retinal vascular occlusion

4.84

4.80

1.2

1.0

—

Retinal vascular disorders

4.84

4.80

1.2

1.0

—

Degeneration of macula and posterior pole

108

2.36

4.79

1.3

1.0

—

Other specified and unspecified disorders of eye and adnexa

9.04

4.78

1.3

1.1

—

Other diseases of intestines

163

620

1.46

4.78

1.1

—

Autoimmune hepatitis, wide definition

9.03

4.78

1.0

1.1

—

Disorders of the thyroid gland

137

589

1.51

4.78

1.2

1.1

—

Cluster headache, wide

5.23

4.77

1.2

1.0

—

Cluster headache, strict, including avohilmo

3.59

4.76

1.1

1.0

—

Certain infectious and parasitic diseases, including avohilmo

293

1.66

4.76

1.1

—

Complications of medical and surgical care

100

562

1.60

4.76

1.1

1.2

—

Hypothyreosis and Thyroxine purchase for inclusion criteria

134

580

1.51

4.75

1.2

1.1

—

Conjunctivitis (acute, non atopic), including avohilmo

141

568

1.50

4.71

1.1

1.2

—

External causes of morbidity and mortality

102

314

1.63

4.68

1.1

1.2

—

Infections of the skin and subcutaneous tissue

552

1.62

4.67

1.1

—

Conjunctivitis

122

644

1.53

4.66

1.2

—

Spondylosis

205

1.94

4.63

1.2

1.1

—

Other and unspecified myopathies

5.01

4.62

1.4

1.0

—

Degenerative macular diseases

5.01

4.62

1.5

1.0

—

Cluster headache, wide,, including avohilmo

3.50

4.61

1.1

1.0

—

L04AC Interleukin inhibitors

3.22

4.61

1.1

—

Other disorders of binocular movement

6.17

4.61

1.0

1.1

—

Vitamin D deficiency

8.26

4.57

1.1

—

Implicit fungal Sepsis

8.22

4.56

1.2

1.0

—

Rheumatism, unspecified

2.97

4.55

1.1

—

Decubitus ulcer and pressure area

10.02

4.52

1.0

—

Injuries to the ankle and foot

118

663

1.52

4.50

1.3

1.1

—

Covid-19 confirmed case

283

1.87

4.50

1.1

—

Irregular menses

100

474

1.59

4.49

1.2

1.1

—

Benign neoplasm of other and unspecified endocrine glands

2.86

4.48

1.2

1.0

—

Viral infections characterized by skin and mucous membrane lesions

363

1.76

4.48

1.1

—

Dissociative [conversion] disorders

3.29

4.47

1.0

1.1

—

Retinal detachment with retinal break

3.42

4.46

1.1

1.0

—

Zoster [herpes zoster]

2.58

4.46

1.0

1.1

—

Other strabismus

209

2.01

4.35

1.1

—

Cerebrovascular diseases (FINNGEN)

158

2.00

4.32

1.1

—

Glaucoma

212

1.92

4.31

1.2

1.1

—

Other diseases of upper respiratory tract

143

506

1.47

4.30

1.1

1.2

—

Appendectomy

102

628

1.55

4.29

1.1

—

Sarcoidosis

2.78

4.28

1.2

1.0

—

Other diseases of gallbladder

11.70

4.27

1.0

—

Persons encountering health services for specific procedures and health care

156

640

1.44

4.27

1.1

1.2

—

Other specified/unspecified arthritis

178

2.08

4.24

1.1

1.2

—

Cardiovascular diseases (excluding rheumatic etc)

131

504

1.49

4.23

1.2

—

Benign neoplasm of meninges

4.13

4.20

1.0

—

Spondylopathies

293

1.65

4.20

1.2

1.1

—

Cramp and spasm

4.82

4.18

1.1

1.0

—

Atypical facial pain

4.82

4.18

1.2

1.0

—

Other disorders of nervous system

5.25

4.14

1.8

1.0

—

Personality disorders, excluding more controls

277

1.84

4.12

1.2

1.1

—

Any dementia, excluding more controls

2.63

4.08

1.4

1.1

—

Psychiatric diseases

127

426

1.49

4.08

1.1

—

Diagnoses used for exclusion with ILD

135

2.22

4.07

1.2

1.1

—

Unspecified haematuria

146

2.06

4.02

1.1

—

Anaphylactic shock due to adverse effect of correct drug or medication properly administered

10.13

4.02

1.0

—

Chronic lower respiratory diseases

171

642

1.40

4.01

1.1

—

Other/unspecified soft tissue disorders related to use, overuse and pressure

10.05

4.01

1.4

1.0

—

Fever of other and unknown origin

363

1.67

4.00

1.3

1.1

—

Systemic lupus erythematosus, unspecified

5.59

3.98

1.8

1.0

—

Pain in thoracic spine

105

2.39

3.97

1.2

1.1

—

Falls/tendency to fall

159

562

1.42

3.93

1.1

1.2

—

Any dementia

2.57

3.91

1.4

1.1

—

Diseases of liver

212

1.94

3.89

1.1

—

Dermatitis

514

1.58

3.88

1.2

1.1

—

Malignant neoplasm of breast, including Hilmo

241

0.35

3.88

1.4

1.1

—

Malignant neoplasm of breast, HER2-negative, including Hilmo

241

0.35

3.88

1.4

1.1

—

Abnormalities of heart beat

282

1.79

3.86

1.1

—

Other symptoms and signs involving general sensations and perceptions

7.30

3.86

1.4

1.1

—

Bacterial Sepsis

197

1.89

3.85

1.1

—

Lesion of lateral popliteal nerve

5.28

3.82

1.2

1.1

—

Implicit Sepsis, including avohilmo

100

470

1.52

3.77

1.2

—

Diarrhoea and gastroenteritis of presumed infectious origin

105

628

1.49

3.77

1.2

1.1

—

Migraine with aura and triptan purchases

222

1.90

3.76

1.2

1.1

—

Dental caries

163

2.03

3.75

1.3

1.1

—

Inflammatory diseases of female pelvic organs

109

500

1.49

3.75

1.1

1.2

—

Chronic hepatitis, not elsewhere classified

6.70

3.67

1.0

—

Gluteal tendinitis

6.69

3.67

1.0

1.1

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

409

1.63

3.66

1.2

1.1

—

Streptococcal septicaemia

4.01

3.59

1.2

1.1

—

Symptoms and signs involving speech and voice

233

1.85

3.58

1.2

1.1

—

Exposure to other and unspecified man-made environmental factors

7.84

3.56

1.3

1.0

—

Immunodeficiency with predominantly antibody defects

7.82

3.56

1.3

1.1

—

Intestinal infectious diseases

131

686

1.42

3.56

1.2

1.1

—

SLE, strict definition

4.79

3.56

1.8

1.1

—

SLE, ICD10

4.79

3.56

1.8

1.1

—

Bell's palsy

2.57

3.54

1.2

1.1

—

Other disorders of the musculoskeletal system and connective tissue

2.57

3.54

1.1

—

Diseases of the respiratory system

294

1.55

3.53

1.1

—

Other obstetric conditions, not elsewhere classified

385

1.53

3.51

1.2

1.1

—

Malignant neoplasm of breast

230

0.36

3.50

1.4

1.1

—

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

301

1.73

3.49

1.2

1.1

—

Sicca syndrome [Sjögren]

3.62

3.49

1.8

1.0

—

Streptococcal septicaemia, including avohilmo

3.88

3.48

1.2

1.1

—

Extrapyramidal and movement disorders

221

1.86

3.48

1.1

—

Malignant neoplasm of breast, HER2-negative

229

0.37

3.47

1.4

1.1

—

Disease of hard tissues of teeth, NOS

199

1.68

3.47

1.1

—

Finngen Rheumatological endpoints

143

579

1.40

3.46

1.1

—

Cardiovascular diseases

127

470

1.43

3.44

1.2

—

Systemic lupus erythematosus

4.57

3.43

1.8

1.1

—

Vitamin deficiency

4.56

3.43

1.2

1.0

—

Vitamin deficiency, wide

4.56

3.43

1.2

1.0

—

Exclusions for E4_PCOS_BROAD

159

2.01

3.42

1.2

1.1

—

Asthma, hospital admissions , main diagnosis only

114

690

1.44

3.40

1.2

1.1

—

Other maltreatment syndromes

4.10

3.40

1.5

1.1

—

Intracranial injury

462

1.55

3.38

1.2

1.1

—

Benign neoplasm: Cerebral meninges

3.76

3.38

1.0

—

Ptosis of eyelid

3.76

3.38

1.0

—

Excessive, frequent and irregular menstruation

251

1.60

3.34

1.2

1.1

—

Chronic sinusitis

366

1.64

3.32

1.2

—

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

380

1.51

3.30

1.2

1.1

—

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

478

1.55

3.30

1.3

1.1

—

Heterophoria

2.62

3.30

1.1

—

Obesity and other hyperalimentation

621

1.47

3.29

1.1

—

Enthesopathies of lower limb, excluding foot

148

2.03

3.29

1.2

1.1

—

Solid cancers

484

0.59

3.28

1.2

1.1

—

Glaucoma secondary to other eye disorders

8.60

3.26

1.3

1.0

—

Oter anti-inflammatory and antirheumatic agents, non-steroids

2.83

3.25

1.1

1.3

—

Dermatitis and eczema

150

648

1.37

3.23

1.2

1.1

—

Benign paroxysmal vertigo

177

1.92

3.22

1.1

—

Certain disorders involving the immune mechanism

136

2.06

3.21

1.3

1.1

—

Benign neoplasm: Pituitary gland, craniopharyngeal duct

3.54

3.19

1.3

1.1

—

Speech disturbances, not elsewhere classified

3.54

3.19

1.0

—

Primary open-angle glaucoma

2.44

3.18

1.0

1.1

—

Oxycodone

145

1.95

3.16

1.1

—

Obesity

621

1.46

3.13

1.1

—

Tinnitus

158

1.96

3.13

1.3

1.1

—

Biomechanical lesions, not elsewhere classified

4.51

3.11

1.0

—

Neuralgia and neuritis, unspecified

4.51

3.11

1.1

—

Other arthritis (FG)

223

1.80

3.09

1.1

—

Disorders of lens

204

1.67

3.06

1.3

1.1

—

Mixed connective tissue disease

7.55

3.06

1.0

—

STROKE

249

1.62

3.03

1.1

—

Keratoconus

5.86

3.02

1.1

1.0

—

Traumatic subdural haemorrhage

5.95

3.02

1.1

1.0

—

Oedema, not elsewhere classified

163

1.92

3.02

1.4

1.1

—

Complications of surgical and medical care, not elsewhere classified

128

618

1.38

2.99

1.1

1.2

—

Memory loss

4.29

2.99

1.3

1.0

—

Other disorders of patella

147

1.98

2.98

1.3

1.1

—

Other and unspecified dermatitis

441

1.54

2.97

1.2

1.1

—

Viral infections of the central nervous system, including avohilmo

2.64

2.96

1.2

1.0

—

Obsessive-compulsive disorder

2.28

2.93

1.1

—

Macular pucker

3.25

2.93

1.1

—

Complications of procedures, not elsewhere classified

104

591

1.42

2.91

1.1

1.2

—

Injury, poisoning and certain other consequences of external causes

268

1.52

2.91

1.1

—

Other retinal disorders

280

1.60

2.90

1.3

1.1

—

Injuries to the wrist and hand

138

674

1.36

2.90

1.1

1.2

—

Polycystic ovarian syndrome, consortium definition

118

484

1.40

2.90

1.3

1.1

—

Exposure to unspecified factor

137

687

1.36

2.88

1.2

—

Other specified/unspecified systemic involvement of connective tissue

3.71

2.88

1.0

—

Benign neoplasm of brain and other parts of central nervous system

3.71

2.88

1.4

1.1

—

Pain associated with micturition

2.43

2.87

1.1

—

Hypermobility syndrome

2.51

2.87

1.1

—

Other congenital malformations of circulatory system

6.70

2.87

1.3

1.0

—

Use of antiglaucoma preparations and miotics

5.39

2.87

1.0

—

109

2.06

2.85

1.1

—

Factors influencing health status and contact with health services

2.00

2.85

1.1

—

Pain and other conditions associated with female genital organs and menstrual cycle

247

1.66

2.83

1.2

1.1

—

Oxicams

2.37

2.81

1.2

1.3

—

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

387

1.56

2.81

1.1

1.2

—

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

462

1.51

2.81

1.1

—

Localized swelling, mass and lump of skin and subcutaneous tissue

201

1.79

2.79

1.2

1.1

—

Cervicalgia

130

2.00

2.79

1.0

1.1

—

Other and unspecified vascular occlusions

4.45

2.79

1.3

1.0

—

Candidiasis, including avohilmo

322

1.62

2.79

1.2

1.1

—

Panic disorder

194

1.81

2.79

1.3

1.1

—

Implicit bacterial Sepsis

165

1.82

2.78

1.1

—

Dementia

2.15

2.76

1.3

1.1

—

Tonsillectomy and adenotomy

111

555

1.39

2.76

1.1

1.2

—

Other mycoses, not elsewhere classified/unspecified, including avohilmo

8.38

2.75

1.6

1.0

—

Spinal stenosis

120

1.90

2.75

1.1

—

Acute tubulo-interstitial nephritis

447

1.47

2.72

1.2

1.1

—

Caries of dentine

140

1.93

2.71

1.3

1.1

—

Malignant neoplasm

502

0.64

2.71

1.1

—

Malignant neoplasm of breast, HER-positive

165

0.36

2.70

1.6

1.1

—

Organic, including symptomatic, mental disorders

130

1.84

2.70

1.4

1.1

—

Malignant neoplasm of breast, ER-positive, including Hilmo

165

0.36

2.70

1.6

1.1

—

Other embolism and thrombosis

2.43

2.70

1.1

—

Spinal instabilities

6.03

2.70

1.0

—

Small fibre neuropathy

6.02

2.70

1.3

1.0

—

Keratitis and keratoconjunctivitis in other diseases classified elsewhere

6.02

2.70

1.2

1.0

—

Multiple myeloma and malignant plasma cell neoplasms

6.02

2.70

1.0

—

Malignant neoplasm

501

0.64

2.69

1.1

—

Hypothyroidism, drug reimbursement

2.02

2.68

1.5

1.1

—

Oesophagitis

4.22

2.68

1.1

1.0

—

Ischaemic Stroke, excluding all haemorrhages

164

1.75

2.67

1.1

—

Other salmonella infections, including avohilmo

3.76

2.67

1.3

1.1

—

Calcific tendinitis of shoulder

3.76

2.67

1.0

—

Herpesviral [herpes simplex] infections

2.18

2.66

1.2

1.1

—

Propionic acid derivatives

1.96

2.65

1.1

1.2

—

Presbyopia

2.80

2.64

1.3

1.0

—

Diseases of male genital organs

144

1.68

2.63

1.1

1.2

—

Viral warts, including avohilmo

235

1.70

2.63

1.1

—

Trochanteric bursitis

2.39

2.62

1.2

1.1

—

Viral infections of the central nervous system

2.66

2.62

1.2

1.0

—

Vestibular neuronitis

2.93

2.61

1.0

—

Dentofacial anomalies [including malocclusion]

111

633

1.37

2.60

1.2

1.1

—

Restless leg syndrome

2.15

2.60

1.2

1.1

—

Disorders of synovium and tendon

371

1.51

2.60

1.2

1.1

—

Inflammatory disease of uterus

184

1.80

2.60

1.1

—

Other metabolic disorders

120

2.00

2.60

1.3

1.1

—

Fenamates

2.48

2.60

1.2

1.3

—

Injuries to the head

148

665

1.32

2.59

1.2

1.1

—

Abnormal findings on diagnostic imaging of lung

188

1.76

2.58

1.1

—

Foreign body in alimentary tract

3.61

2.57

1.3

1.0

—

Skin changes due to chronic exposure to nonionizing radiation

2.11

2.57

1.0

1.1

—

Amblyopia ex anopsia

4.01

2.57

1.0

1.1

—

Bacterial infection, other or unspecified

263

1.60

2.56

1.1

—

Additional codes for the location of defect, injury or illness

3.06

2.56

1.0

1.1

—

Benzodiazepine use

131

661

1.34

2.56

1.2

1.1

—

Implicit bacterial Sepsis, including avohilmo

183

1.73

2.56

1.1

—

Internal derangement of knee

280

1.63

2.56

1.2

1.1

—

Other disorders of binocular vision

7.20

2.55

1.4

1.1

—

Exposure to smoke, fire and flames

7.17

2.55

1.0

—

Other specified disorders of muscle

7.17

2.55

1.0

—

Presence of other functional implants

196

1.64

2.55

1.2

1.1

—

Other abnormal immunological findings in serum

5.49

2.54

1.3

1.1

—

Anomalies of pupillary function

5.48

2.54

1.3

1.1

—

Zoster [herpes zoster], including avohilmo

341

1.56

2.54

1.2

1.1

—

Neovascular glaucoma

5.47

2.54

1.3

1.0

—

Multiple myeloma, including Hilmo

5.47

2.54

1.0

1.1

—

Other/unspecified rheumatoid arthritis

2.73

2.54

1.0

—

Antihypertensive medication - note that there are other indications

121

465

1.36

2.52

1.1

—

Obesity related asthma

269

1.64

2.51

1.1

—

Abnormalities of breathing

124

526

1.35

2.49

1.2

1.1

—

Condition for Implicit Sepsis (Organ dysfunction codes)

476

1.40

2.48

1.2

—

Adverse effects, not elsewhere classified

217

1.71

2.47

1.3

1.1

—

Solid cancers, including Hilmo

509

0.66

2.46

1.1

—

Recurrent dislocation of patella

2.39

2.46

1.5

1.0

—

Prolonged pregnancy

267

0.45

2.46

1.1

—

Other disorders of the genitourinary system

2.67

2.45

1.2

1.0

—

Explicit bacterial Sepsis

2.55

2.44

1.2

1.1

—

Explicit bacterial Sepsis, including avohilmo

2.55

2.44

1.2

1.1

—

Persons encountering health services for specific procedures, not carried out

2.24

2.44

1.2

1.1

—

Fall on same level

157

644

1.30

2.43

1.1

1.2

—

Other and unspecified effects of external causes

311

1.58

2.42

1.3

1.1

—

Actinic keratosis

2.09

2.40

1.0

1.1

—

Meningitis

3.34

2.39

1.2

1.0

—

Deviated nasal septum

204

1.71

2.38

1.1

—

Retinal breaks without detachment

2.35

2.38

1.2

1.0

—

Constipation

100

492

1.38

2.38

1.2

1.1

—

Primary Sclerosing Cholangitis, IBD and UDCA required

6.28

2.37

1.0

—

Systemic sclerosis (FG)

6.28

2.37

1.0

—

Cerebrovascular diseases

269

1.52

2.36

1.1

—

Pregnancy with abortive outcome

105

398

1.37

2.36

1.2

—

Mental and behavioural disorders due to cannabinoids

3.05

2.36

1.0

1.2

—

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

449

1.47

2.35

1.1

—

Other hearing loss

101

2.01

2.32

1.2

1.1

—

Benign neoplasm: Colon, unspecified

2.09

2.32

1.2

1.1

—

Otitis externa, unspecified

105

2.00

2.30

1.1

—

Triptan medication for migraine, min. 3 purchases

102

561

1.36

2.29

1.2

1.1

—

Fall on same level involving ice and snow

486

1.44

2.28

1.1

—

Other inflammation of eyelid

2.12

2.28

1.2

1.1

—

Other and unspecified disorders of white blood cells

4.63

2.27

1.2

1.0

—

Normotensive glaucoma

4.62

2.27

1.0

1.1

—

Other symptoms and signs involving the circulatory and respiratory systems

2.76

2.27

1.0

1.1

—

Other disorders of white blood cells

3.49

2.27

1.1

1.0

—

Vitreous haemorrhage

2.56

2.27

1.1

—

Hypothyroidism, strict autoimmune, 3 medication purchases required

110

550

1.34

2.26

1.2

1.1

—

Irritable bowel syndrome

262

1.60

2.25

1.2

1.1

—

Primary_lymphoid and hematopoietic malignant neoplasms

106

1.98

2.25

1.0

1.1

—

Disorders of muscles

2.28

2.24

1.2

1.1

—

Convulsions, not elsewhere classified

176

1.74

2.24

1.1

—

Caries of enamel

129

644

1.31

2.23

1.2

—

Parkinson's disease, strict definition

3.11

2.22

1.1

1.0

—

Vocal cord dysfunction

1.99

2.22

1.3

1.1

—

Systemic sclerosis, icd10

5.58

2.21

1.0

—

Systemic sclerosis

5.58

2.21

1.0

—

Benign neoplasm of other and unspecified sites

5.57

2.21

1.2

1.0

—

Abnormal findings on diagnostic imaging of other body structures

2.19

2.20

1.2

1.1

—

Non-selective monoamine reuptake inhibitors

208

1.66

2.20

1.1

—

Special screening examination for other diseases and disorders

2.19

2.20

1.3

1.1

—

Medicines for HER+ breast cancer

226

0.41

2.19

1.6

1.1

—

Benign neoplasm: Colon

225

1.63

2.19

1.1

—

Herpesviral [herpes simplex] infections, including avohilmo

304

1.55

2.18

1.3

1.1

—

Personality disorders

336

1.52

2.17

1.2

1.1

—

Other enthesopathies

203

1.68

2.16

1.2

1.1

—

Cervical disc disorders

173

1.74

2.16

1.3

1.1

—

Other specified and unspecified personality disorders

2.03

2.15

1.1

—

Other facial nerve disorders

4.30

2.15

1.3

1.1

—

Psoriasis (vulgaris), strict definition

4.30

2.15

1.0

—

Reimbursement for rheumatic diseases

465

1.43

2.14

1.1

—

Exposure to other specified factors

109

706

1.33

2.14

1.3

1.1

—

Stroke, excluding SAH

184

1.61

2.12

1.1

—

Bacterial infection, other or unspecified, including avohilmo

315

1.48

2.12

1.1

—

Conjunctivitis (acute, non atopic)

281

1.56

2.12

1.2

1.1

—

Allergic conjunctivitis

622

1.36

2.10

1.2

—

Other disorders of adrenal gland

3.21

2.09

1.3

1.1

—

Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies

3.21

2.09

1.1

1.0

—

Transient ischemic attack

168

1.66

2.08

1.0

1.1

—

Viral meningitis, including avohilmo

2.91

2.07

1.2

1.0

—

Otalgia

2.26

2.07

1.4

1.0

—

Obesity, other/unspecified

389

1.47

2.07

1.1

—

Other/unspecified disorders of vestibular function

5.01

2.07

1.6

1.0

—

Hypercalcemia

5.01

2.07

1.4

1.0

—

Cerebral aneurysm, nonruptured

2.71

2.07

1.0

—

Parkinson's disease, including avohilmo

2.70

2.06

1.1

1.0

—

Lung diseases due to external agents

2.70

2.06

1.1

—

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

304

1.43

2.06

1.1

1.2

—

Other arthrosis

209

1.54

2.05

1.1

—

Disorders of orbit

3.51

2.05

1.4

1.1

—

Adrenocortical insufficiency

4.01

2.04

1.3

1.1

—

Carcinoma in situ of skin of other and unspecified parts of face

4.00

2.04

1.0

1.1

—

Diseases of pulp and periapical tissues, including avohilmo

135

541

1.29

2.03

1.1

1.2

—

Malignant neoplasm, including Hilmo

528

0.71

2.02

1.1

—

Stroke, including SAH

197

1.57

2.01

1.1

—

Arthrosis

301

1.40

2.01

1.1

—

Malignant neoplasm, wide definition

527

0.71

2.01

1.1

—

Other inflammatory liver diseases

2.82

2.00

1.0

1.1

—

Other extrapyramidal and movement disorders in other diseases

163

1.72

1.97

1.1

—

Dementia, including avohilmo

1.87

1.97

1.3

1.1

—

Disorders of adult personality and behaviour

369

1.47

1.97

1.2

1.1

—

Algoneurodystrophy

3.35

1.96

1.0

—

Tongue abnormality

3.34

1.96

2.0

1.0

—

Carcinoma in situ of skin

3.34

1.96

1.0

—

Iron deficiency anaemia

306

1.51

1.96

1.1

—

156

1.73

1.95

1.2

1.1

—

Undetermined asthma

2.08

1.95

1.4

1.1

—

Osteoporosis

1.99

1.95

1.6

1.1

—

Glaucoma suspect

156

1.73

1.95

1.1

—

Other disorders of cornea

2.36

1.94

1.1

1.0

—

Cholecystitis

2.35

1.94

1.0

1.1

—

Other hammer toe(s) (acquired)

2.37

1.94

1.0

1.1

—

Other salmonella infections

4.56

1.94

1.6

1.0

—

Other and unspecified abdominal hernia

4.56

1.94

1.0

—

Mixed hyperlipidaemia

4.56

1.94

1.0

—

Attention to artificial openings

4.56

1.94

1.2

1.0

—

Glaucoma-related operations

4.55

1.94

1.0

—

Symptoms and signs concerning food and fluid intake

2.35

1.94

1.3

1.1

—

Meralgia paraesthetica

3.76

1.93

1.2

1.0

—

Diabetic retinopathy

104

1.73

1.93

1.1

1.2

—

Diabetic neuropathy

2.55

1.92

1.1

1.0

—

Other ulcerative colitis

0.00

1.88

0.0

1.1

—

Primary open-angle glaucoma, strict

2.15

1.86

1.0

1.1

—

Unspecified urinary incontinence

2.65

1.86

1.1

—

Spontaneous rupture of synovium and tendon

2.65

1.86

1.2

1.0

—

Acute pancreatitis

107

1.87

1.85

1.3

1.1

—

Undetermined asthma, excluding more controls

2.03

1.84

1.4

1.1

—

Unspecified maternal hypertension

3.56

1.84

1.0

1.1

—

Functional dyspepsia

221

1.59

1.84

1.3

1.1

—

Endometriosis of pelvic peritoneum

179

1.63

1.84

1.3

1.2

—

Condition for Implicit Sepsis (Organ dysfunction codes), including avohilmo

105

543

1.30

1.83

1.2

1.1

—

Anti-inflammatory and antirheumatic products, non-steroids

1.76

1.83

1.1

1.2

—

Atopic dermatitis, strict definition with reimbursement

400

1.42

1.82

1.2

1.1

—

Alzheimer disease, excluding more controls

4.62

1.82

1.2

1.0

—

Other viral diseases, including avohilmo

471

1.39

1.82

1.2

—

Senile cataract

151

1.57

1.82

1.4

1.0

—

Other and unspecified iron deficiency

253

1.54

1.81

1.1

—

Acute pancreatitis (for exclusion)

108

1.85

1.81

1.3

1.1

—

Urticaria

343

1.46

1.81

1.1

1.2

—

Unspecified/other endometriosis

142

1.73

1.80

1.1

—

Generalized anxiety disorder

222

1.58

1.80

1.2

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

2.58

1.80

1.1

—

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

3.05

1.80

1.1

—

Other cataract

146

1.63

1.79

1.3

1.1

—

Atopic dermatitis

583

1.31

1.79

1.2

1.1

—

Other and unspecified psoriasis

2.76

1.79

1.0

—

Benign neoplasm: Adrenal gland

2.76

1.79

1.0

—

Diseases of appendix

656

1.31

1.79

1.2

1.1

—

Superficial injury of wrist and hand

231

1.56

1.78

1.3

1.1

—

Mycoses

231

1.56

1.78

1.3

1.1

—

Other viral hepatitis

2.17

1.77

1.2

1.1

—

Other viral hepatitis, including avohilmo

2.09

1.76

1.1

—

Dermatographic urticaria

2.09

1.76

1.1

—

Appendicitis, broad definition

653

1.31

1.75

1.2

1.1

—

Postprocedural endocrine and metabolic disorders, not elsewhere classified

110

1.82

1.72

1.3

1.1

—

Viral meningitis

2.68

1.72

1.3

1.0

—

Sleep disorders, other/unspecified

2.67

1.72

1.1

—

Need for other prophylactic measures

2.67

1.72

1.1

—

Immunodeficiencies

2.92

1.72

1.3

1.0

—

Autoimmune thyroiditis

3.86

1.71

1.0

1.1

—

Bacterial meningitis

3.86

1.71

1.4

1.0

—

All influenza

194

1.60

1.70

1.1

—

Calculus of kidney and ureter

171

1.64

1.69

1.8

1.1

—

Other sleep disorders

2.00

1.69

1.0

1.1

—

Diseases of external ear

283

1.49

1.68

1.1

—

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

586

1.32

1.68

1.2

—

Other disorders of eyelid

169

1.62

1.67

1.1

—

Other diseases of arteries and capillaries

2.50

1.66

1.1

—

Specific personality disorders

292

1.47

1.66

1.0

1.1

—

Pustulosis palmaris et plantaris

3.17

1.66

1.2

1.1

—

Acne, including avohilmo

322

1.41

1.66

1.3

1.1

—

Other mental disorders due to brain damage and dysfunction and to physical disease

2.58

1.65

1.5

1.1

—

DVT of lower extremities

1.86

1.65

1.1

—

Other diseases of hard tissues of teeth

199

1.43

1.65

1.1

—

Medical abortion

394

1.31

1.64

1.1

1.2

—

Benign neoplasms

132

574

1.25

1.64

1.2

1.1

—

Nutritional anaemias

334

1.43

1.63

1.1

—

Urolithiasis

181

1.60

1.62

1.7

1.1

—

Septicaemia

215

1.53

1.62

1.2

1.1

—

Molar incisor enamel hypoplasia

2.40

1.62

1.0

1.2

—

Atopic dermatitis, strict definition

393

1.39

1.61

1.2

—

Sacrococcygeal disorders, not elsewhere classified

3.58

1.61

1.0

1.1

—

Bullous disorders

3.58

1.61

1.2

1.0

—

Ascites

3.58

1.61

1.4

1.0

—

All kidney diseases

122

651

1.25

1.61

1.3

1.1

—

Glaucoma, exfoliation

3.57

1.61

1.0

1.1

—

Hernia of abdominal wall, postoperative

1.92

1.61

1.2

1.1

—

Hypopituitarism

2.15

1.60

1.2

1.1

—

Crohn disease

134

0.37

1.60

1.2

1.1

—

Dermatophytosis, including avohilmo

605

1.31

1.59

1.2

1.1

—

Abnormal weight loss

2.33

1.58

1.1

—

Benign neoplasm: Ascending colon

2.33

1.58

1.1

—

Cholangitis (primary sclerosing, PSC)

3.00

1.58

1.0

—

Pneumonitis due to solids and liquids

3.00

1.58

1.0

1.1

—

Acute appendicitis, no complications

589

1.32

1.58

1.2

1.1

—

Disorders of calcium metabolism

2.70

1.58

1.3

1.1

—

L02BG Aromatase inhibitors

170

0.46

1.57

1.4

1.2

—

Assault

152

1.65

1.56

1.2

1.1

—

Acute appendicitis

648

1.29

1.55

1.2

1.1

—

Sudden idiopathic hearing loss

2.28

1.55

1.4

1.0

—

Astigmatism

2.27

1.55

1.2

1.1

—

Injuries to the knee and lower leg

150

662

1.22

1.55

1.2

—

Sleep disorders

117

643

1.25

1.54

1.1

1.2

—

Neoplasms

121

506

1.25

1.54

1.1

—

Endometriosis of rectovaginal septum and vagina

2.04

1.54

1.2

1.1

—

Abnormal findings on examination of blood, without diagnosis

261

1.46

1.53

1.2

1.1

—

Other and unspecified acne

3.35

1.52

1.6

1.1

—

Congenital malformations of the urinary system, including avohilmo

0.00

1.52

0.0

1.0

—

Open wound of abdomen, lower back and pelvis

3.34

1.52

1.0

1.1

—

Barrett oesophagus

3.34

1.52

1.0

—

Autoimmune hyperthyroidism

3.34

1.52

1.6

1.1

—

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

249

1.49

1.51

1.1

—

Osteopathies and chondropathies

387

1.37

1.51

1.2

—

Diseases of tongue

2.60

1.51

2.0

1.0

—

Contusion of toe(s) without damage to nail

2.87

1.50

1.7

1.0

—

Chondrocostal junction syndrome [Tietze]

2.86

1.50

1.0

—

Pustular psoriasis

2.86

1.50

1.2

1.1

—

Cyst of kidney

2.86

1.50

1.0

—

106

489

1.27

1.50

1.1

—

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

106

489

1.27

1.50

1.1

—

Nonorganic sleeping disorders, excluding more controls

209

1.53

1.50

1.3

1.1

—

Fentanyl

2.85

1.50

1.3

1.1

—

Malignant neoplasm of breast, ER-negative, including Hilmo

117

0.40

1.50

1.0

1.1

—

Postpartum haemorrhage due to retained placenta

184

0.49

1.49

1.1

—

Benign neoplasm of colon, rectum, anus and anal canal

266

1.43

1.49

1.2

1.1

—

Renal tubulo-interstitial diseases

102

591

1.26

1.48

1.2

1.1

—

Atopic conjunctivitis

2.44

1.48

1.0

1.1

—

Oral leukoplakia and other epithelial disorders of tongue and oral cavity , including avohilmo

2.44

1.47

1.1

—

Parkinson's disease

2.43

1.47

1.1

1.0

—

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

518

1.29

1.47

1.1

—

Hypoplasia of dental enamel , including avohilmo

2.41

1.47

1.0

1.1

—

Convergent concomitant strabismus

2.23

1.46

1.0

1.1

—

Gingivitis and periodontal diseases

113

465

1.25

1.46

1.1

1.2

—

Epilepsy

210

1.52

1.46

1.2

1.1

—

Acute pharyngitis

177

1.57

1.45

1.4

1.1

—

Enterocolitis due to Clostridium difficile

2.37

1.45

1.1

—

Postprocedural musculoskeletal disorders, not elsewhere classified

2.50

1.45

1.1

1.0

—

Polyarthritis, unspecified

3.13

1.44

1.4

1.0

—

Ulcer of oesophagus

3.13

1.44

1.0

1.1

—

Viral hepatitis

1.97

1.43

1.2

1.1

—

Urticaria and erythema

395

1.37

1.43

1.2

1.1

—

Use of hypnotics and sedatives

126

584

1.23

1.42

1.2

1.1

—

Superficial injury of abdomen, lower back and pelvis

141

1.63

1.41

1.2

1.1

—

Behavioural syndromes associated with physiological disturbances and physical factors

118

646

1.24

1.40

1.1

1.2

—

Disorders of skin appendages

549

1.31

1.40

1.2

—

Dyspnoea

100

574

1.26

1.40

1.2

1.1

—

Scleritis and episcleritis

2.25

1.40

1.0

1.1

—

Benign neoplasm of eye and adnexa

2.18

1.39

1.1

1.0

—

Other and unspecified nerve root and plexus disorders, also in other diseases

165

1.58

1.39

1.0

1.1

—

Other diseases of liver

126

1.67

1.39

1.0

1.1

—

Hypermetropia

2.18

1.39

1.0

1.2

—

Voice disturbances

189

1.54

1.39

1.1

—

Acute bronchitis

323

1.40

1.38

1.1

—

Other skin changes

1.77

1.38

1.0

1.1

—

Disorders of other endocrine glands

408

1.35

1.38

1.1

1.2

—

Malignant neoplasm of digestive organs

125

0.49

1.38

1.3

1.1

—

Diseases of middle ear and mastoid

587

1.27

1.38

1.1

—

All influenza (not pneumonia)

119

1.68

1.37

1.1

—

Pedestrian injured in transport accident

2.20

1.37

1.1

1.0

—

Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

2.20

1.37

1.3

1.0

—

Disorders of mineral metabolism

2.20

1.37

1.2

1.0

—

Familial hypercholesterolemia

2.20

1.36

1.2

1.0

—

Fibrosis and cirrhosis of liver

2.61

1.36

1.3

1.0

—

Symptoms and signs involving emotional state

2.95

1.36

1.0

1.1

—

Herpesviral keratitis and keratoconjunctivitis

2.95

1.36

1.2

1.1

—

Pneumonia due to Streptococcus pneumoniae

2.95

1.36

1.0

—

Other spirochaetal diseases

256

1.45

1.35

1.3

1.1

—

Habitual aborter

0.00

1.34

0.0

1.2

—

Presbycusis

2.91

1.34

1.0

1.1

—

Tobacco use

2.15

1.33

1.0

—

Insomnia

115

651

1.23

1.32

1.1

1.2

—

Weight loss

2.04

1.32

1.1

—

Malignant neoplasm of digestive organs, including Hilmo

144

0.51

1.31

1.2

1.1

—

Persons encountering health services in circumstances related to reproduction

377

1.30

1.31

1.2

1.1

—

Obesity due to excess calories

523

1.30

1.31

1.1

—

Twin gestation

146

0.48

1.31

1.0

1.1

—

Hypertensive diseases (excluding secondary)

347

1.29

1.30

1.2

1.1

—

Dermatitis due to substances taken internally

2.50

1.30

1.5

1.0

—

Excessive attrition of teeth

649

1.27

1.30

1.2

1.1

—

Transport accidents

377

1.32

1.29

1.1

1.2

—

Other infective otitis externa

2.36

1.29

1.3

1.1

—

Other disorders of male genital organs

2.78

1.28

1.0

1.1

—

Other epidermal thickening

2.78

1.28

1.0

1.1

—

Explicit Sepsis, including avohilmo

272

1.40

1.28

1.2

1.1

—

Sequelae of external causes of morbidity and mortality

177

1.53

1.28

1.1

—

Polyp of the female genital tract

168

0.61

1.28

1.1

1.2

—

Divergent concomitant strabismus

2.09

1.27

1.1

—

Collagenous colitis

2.00

1.27

1.2

1.0

—

Ulcerative colitis

243

0.58

1.27

1.0

1.1

—

Anankastic personality disorder

2.29

1.27

1.0

1.1

—

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

113

622

1.22

1.26

1.1

1.2

—

Inflammatory bowel disease

329

0.64

1.26

1.0

1.1

—

Asthma/COPD (KELA code 203)

117

641

1.22

1.26

1.2

1.1

—

Fissure and fistula of anal and rectal regions

170

1.53

1.25

1.3

1.1

—

Hypo-osmolality and hyponatraemia

1.99

1.24

1.6

1.1

—

Other/unspecified enthesopathies of lower limb, excluding foot

2.00

1.23

1.0

1.1

—

Other bursopathies

1.91

1.22

1.0

—

Substance abuse, excluding more controls

375

1.31

1.22

1.2

1.1

—

Asthma-related pneumonia

236

1.44

1.22

1.2

1.1

—

Asthma, hospital admissions 3, pneumonia

236

1.44

1.22

1.2

1.1

—

Asthma-related pneumonia or sepsis

236

1.44

1.22

1.2

1.1

—

Other spirochaetal diseases, including avohilmo

262

1.41

1.22

1.3

1.1

—

Other peripheral vascular diseases

2.04

1.22

1.1

1.0

—

Liquid cancers

139

1.57

1.22

1.0

1.1

—

Other septicaemia, including avohilmo

191

1.47

1.21

1.1

—

Conduct disorder

2.64

1.21

1.2

1.1

—

Generalized skin eruption due to drugs and medicaments

2.64

1.21

1.6

1.1

—

Brain meningioma

2.64

1.21

1.0

1.1

—

Brain meningioma, including Hilmo

2.64

1.21

1.0

1.1

—

Myocardial infarction

142

0.54

1.21

1.1

—

Amputation

2.63

1.21

1.0

1.1

—

Reactive arthropathies, FINNGEN

2.17

1.21

1.0

1.1

—

Lyme disease

254

1.42

1.21

1.3

1.1

—

Lyme disease, including avohilmo

254

1.42

1.21

1.3

1.1

—

Viral hepatitis, including avohilmo

1.80

1.21

1.1

—

Keratitis

322

1.37

1.20

1.1

—

Allergic urticaria

1.83

1.19

1.2

1.1

—

Unspecified privation

1.83

1.19

1.2

1.1

—

Abnormal blood-pressure reading, without diagnosis

2.31

1.18

1.0

—

Delirium, not induced by alcohol and other psychoactive substances

2.30

1.18

1.0

—

Other acute lower respiratory infections

440

1.30

1.17

1.1

1.2

—

Other noninfective gastroenteritis and colitis

214

1.45

1.17

1.1

—

Otitis externa

206

1.46

1.17

1.1

—

Other diseases of intestine

1.93

1.16

1.3

1.1

—

Diabetic retinopathy, excluding more controls

1.60

1.16

1.1

—

Subacute thyroiditis

2.50

1.15

1.2

1.1

—

Traumatic amputation of wrist and hand

2.50

1.15

1.0

—

Amenorrhoea

110

1.64

1.15

1.3

1.1

—

Familial hypercholesterolemia, with ischemic heart disease

2.50

1.15

1.2

1.1

—

Haemorrhoids and perianal venous thrombosis

197

1.46

1.15

1.2

1.1

—

Spirochaetal infections, other/unspecified, including avohilmo

257

1.40

1.15

1.3

1.1

—

Misadventures to patients during surgical and medical care

1.73

1.15

1.2

1.1

—

Speech therapy

166

1.51

1.14

1.2

1.1

—

Postpartum hemorraghe, all women as controls

439

0.71

1.14

1.2

1.1

—

Congenital malformations of the urinary system

0.00

1.14

0.0

1.0

—

Other inflammation of eyelid, including avohilmo

500

1.28

1.14

1.2

1.1

—

Multiple gestation

153

0.52

1.13

1.0

1.1

—

Malignant neoplasm of skin

185

0.62

1.13

1.4

1.1

—

Rotator cuff syndrome

252

1.34

1.13

1.0

1.1

—

Trigger finger

1.75

1.12

1.1

—

Hordeolum and other deep inflammation of eyelid

2.00

1.12

1.0

1.1

—

Hypertension, essential

416

1.24

1.12

1.1

—

Flat foot [pes planus] (acquired)

1.96

1.11

1.0

1.1

—

Spondylopathies (FG)

127

1.58

1.11

1.2

1.1

—

Candidiasis

127

1.58

1.11

1.3

1.1

—

Other specified/unspecified hearing loss

2.26

1.10

1.0

1.1

—

Thiazolidinediones

2.26

1.10

1.0

1.1

—

Fracture of skull and facial bones

176

1.48

1.09

1.3

1.1

—

Acute generalized exanthematous pustulosis

2.38

1.09

1.6

1.0

—

Other abnormal findings of blood chemistry

2.38

1.09

1.0

—

Use of biperiden

2.38

1.09

1.0

—

Benign neoplasm: Choroid

2.38

1.09

1.0

—

Benign neoplasm: Descending colon

2.38

1.09

1.0

—

Unspecified kidney failure

2.38

1.09

1.4

1.0

—

Psychotic depression

1.95

1.08

1.0

—

Cervicobrachial syndrome

144

1.53

1.08

1.4

1.1

—

Other orthopaedic follow-up care

2.19

1.08

1.0

—

Corns and callosities

2.19

1.08

1.0

1.1

—

Nonsuppurative otitis media, including avohilmo

374

1.29

1.07

1.2

—

Childhood asthma (age<16), excluding more controls

150

1.46

1.07

1.2

1.1

—

Emotionally unstable personality disorder

177

1.47

1.07

1.1

—

Other disorders of conjunctiva

1.87

1.07

1.0

1.1

—

Other disorders of fluid, electrolyte and acid-base balance

136

1.52

1.06

1.4

1.1

—

Ankylosing spondylitis

1.93

1.06

1.1

—

Nummular dermatitis

2.12

1.05

1.0

—

Hard cardiovascular diseases

354

1.25

1.05

1.0

1.1

—

Superficial injury of lower leg

262

1.37

1.05

1.1

—

Childhood asthma (age<16)

151

1.45

1.04

1.2

1.1

—

Noninflammatory disorders of female genital tract

251

1.28

1.04

1.1

—

Glucagon-like peptide-1 (GLP-1) analogues

220

1.41

1.04

1.1

—

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

220

1.41

1.04

1.1

—

Dislocation, sprain and strain of joints and ligaments at neck level

195

1.44

1.04

1.1

—

Injuries to the neck

254

1.38

1.04

1.1

—

Injuries involving multiple body regions

2.28

1.03

1.0

—

Hyperhidrosis

2.28

1.03

1.0

1.1

—

Synovial cyst of popliteal space [Baker]

2.27

1.03

1.0

—

Medical treatment for female infertility

379

0.70

1.03

1.1

—

Dialysis, with operation codes

1.83

1.02

1.4

1.1

—

Blepharochalasis

106

1.60

1.02

1.1

—

Hallux rigidus

1.92

1.02

1.0

1.1

—

Paracetamol or NSAID medication

1.72

1.01

1.1

1.2

—

Foreign body or object entering through skin

1.89

1.01

1.2

1.1

—

Malignant neoplasm of breast, HER-negative

102

0.47

1.01

1.0

1.1

—

Diseases of the digestive system

296

1.34

1.01

1.2

1.1

—

Single spontaneous delivery

246

0.73

1.00

1.1

1.2

—

Benign neoplasm: Transverse colon

2.00

1.00

1.0

1.1

—

Any event in cancer register

597

0.82

1.00

1.2

1.1

—

Bitten or struck by other mammals

131

1.53

0.99

1.3

1.1

—

Other complications of labour and delivery, not elsewhere classified

232

0.65

0.99

1.1

—

Gonarthrosis

221

1.30

0.98

1.0

1.1

—

Reactive arthropathies

1.84

0.98

1.0

1.1

—

Intermittent heterotropia

1.84

0.98

1.0

1.1

—

Alcohol withdrawal state with delirium

2.18

0.98

1.0

—

Endometriosis

233

1.30

0.98

1.2

1.1

—

Vasomotor and allergic rhinitis

396

1.28

0.97

1.2

—

Viral conjunctivitis, including avohilmo

1.95

0.97

1.0

1.1

—

Chronic suppurative otitis media

1.95

0.97

1.0

1.1

—

Other viral diseases

343

1.31

0.97

1.1

1.2

—

Chronic viral hepatitis

1.86

0.96

1.1

—

Other disorders of kidney and ureter

1.85

0.96

1.0

1.1

—

Superficial injury of shoulder and upper arm

100

1.60

0.96

1.3

1.1

—

Injury of muscle and tendon at lower leg level

100

1.60

0.96

1.1

—

Polyarthropathies

373

1.24

0.96

1.1

—

Colon adenocarcinoma

0.00

0.96

0.0

1.1

—

Other maternal disorders predominantly related to pregnancy

443

1.21

0.95

1.2

1.1

—

Endometriosis ASRM stages 1,2

233

1.37

0.95

1.3

1.1

—

Benign neoplasm of mouth and pharynx

1.77

0.94

1.1

1.0

—

Nail disorders

1.78

0.94

1.0

—

Nonspecific lymphadenitis

1.89

0.94

1.0

1.1

—

Pediculosis, acariasis and other infestations

1.89

0.94

1.3

1.1

—

Hydrocele

1.89

0.94

1.0

1.1

—

Explicit Sepsis

267

1.33

0.94

1.2

1.1

—

Multiple delivery

116

0.52

0.94

1.0

1.1

—

Uterine polyps

152

0.65

0.93

1.1

1.2

—

Allergic rhinitis

368

1.29

0.93

1.1

—

Cutaneous abscess, furuncle and carbuncle

251

1.36

0.93

1.2

1.1

—

Shoulder lesions

328

1.24

0.92

1.1

—

Complications of internal orthopaedic prosthetic devices, implants and grafts

1.72

0.92

1.0

1.1

—

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

321

1.31

0.92

1.2

1.1

—

Myocardial infarction, strict

131

0.59

0.92

1.1

—

Diseases of oesophagus, stomach and duodenum

123

620

1.17

0.91

1.2

1.1

—

Allergic asthma (mode)

246

1.35

0.91

1.2

1.1

—

Diverticular disease of intestine

242

1.29

0.91

1.3

1.1

—

Chronic rhinitis, nasopharyngitis and pharyngitis

296

1.32

0.90

1.1

1.2

—

Viral haemorrhagic fevers, not elsewhere classified/unspecified, including avohilmo

110

1.55

0.90

1.2

1.1

—

Sequelae of other external causes

2.07

0.89

1.0

1.1

—

Other disorders of ear

491

1.20

0.89

1.2

1.1

—

Fracture of shoulder and upper arm

254

0.67

0.89

1.2

1.1

—

Meniscus derangement

236

1.29

0.88

1.1

—

Agoraphobia

1.91

0.88

1.4

1.1

—

Other/unspecified reactive arthropathies

1.91

0.88

1.0

—

Other disorders of penis

1.90

0.88

1.3

1.1

—

Type 1 diabetes, definitions combined

127

0.55

0.88

1.1

—

Overexertion and strenuous or repetitive movements

1.65

0.88

1.4

1.1

—

Abscess of anal and rectal regions

1.79

0.87

1.0

1.1

—

Dental caries, including avohilmo

277

1.24

0.87

1.1

1.2

—

Viral warts

1.61

0.87

1.1

—

Allergic asthma (mode), excluding more controls

248

1.34

0.87

1.2

1.1

—

Influenza and pneumonia

129

686

1.16

0.87

1.1

1.2

—

Scabies

2.00

0.87

1.3

1.1

—

Cardiomyopathy, other and unspecified

2.00

0.87

1.2

1.1

—

Malignant neoplasm of eye, brain and central nervous system, including Hilmo

2.00

0.87

1.0

1.1

—

Volume depletion

2.00

0.87

1.2

1.1

—

Phlebitis and thrombophlebitis (not including DVT)

161

1.43

0.86

1.0

1.1

—

Exposure to other and unspecified inanimate mechanical forces

1.72

0.86

1.2

1.1

—

Dermatitis due to ingested food

1.98

0.86

1.8

1.2

—

Other disorders of bone

178

1.41

0.86

1.0

1.1

—

Other and unspecified coagulation defects

1.82

0.86

1.1

1.0

—

Chronic suppurative otitis media, including avohilmo

1.82

0.85

1.0

—

Injuries to the abdomen, lower back, lumbar spine and pelvis

338

1.28

0.85

1.2

1.1

—

Early lumbar disc prolapse, operated

112

1.52

0.84

1.0

1.1

—

Intestinal malabsorption

1.94

0.84

1.3

1.1

—

Dermatophytosis

1.63

0.84

1.4

1.1

—

Unknown and unspecified causes of morbidity

1.94

0.84

1.3

1.0

—

Benign neoplasm: Stomach

1.94

0.84

1.8

1.0

—

Vitamin B12 deficiency anaemia

1.94

0.84

1.0

1.1

—

Ulcerative colitis (strict definition, require KELA)

179

0.61

0.84

1.0

1.1

—

Helminthiases, including avohilmo

1.78

0.84

1.3

1.0

—

Impacted cerumen

1.78

0.84

1.0

1.1

—

Inflammatory diseases of prostate (prostatitis)

1.78

0.84

1.1

—

Hypertension

441

1.19

0.84

1.1

—

Postpartum haemorrhage

350

0.75

0.84

1.2

1.1

—

Other contact dermatitis

1.76

0.83

1.0

—

Chronic pancreatitis

1.76

0.83

1.2

1.1

—

Infections with a predominantly sexual mode of transmission, including avohilmo

553

1.21

0.83

1.1

1.2

—

Cardiodefibrillation

111

0.54

0.83

1.0

1.1

—

Other and unspecified urticaria

205

1.37

0.83

1.2

1.1

—

Other septicaemia

185

1.38

0.82

1.1

—

Infectious mononucleosis

121

1.49

0.82

1.2

1.1

—

Infectious mononucleosis, including avohilmo

121

1.49

0.82

1.2

1.1

—

Asthma and allergy, excluding more controls

144

1.44

0.82

1.1

—

Asthma and allergy

144

1.44

0.82

1.1

—

Liquid cancers, including Hilmo

173

1.38

0.82

1.0

1.1

—

Premature rupture of membranes

285

0.75

0.82

1.1

—

Nasal polyp

113

1.51

0.82

1.4

1.1

—

Other and/or unspecified nontoxic goitre

1.88

0.81

1.5

1.1

—

Other female pelvic inflammatory diseases

138

1.45

0.81

1.1

—

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

177

0.62

0.81

1.0

1.1

—

Hypertensive diseases

443

1.18

0.81

1.1

—

Sacroiliitis, not elsewhere classified

1.70

0.80

1.1

—

Elevated blood glucose level

1.70

0.80

1.1

1.0

—

Suppurative and unspecified otitis media

457

1.22

0.80

1.2

—

Seropositive rheumatoid arthritis

121

1.48

0.80

1.1

—

Preterm labour and delivery

267

1.31

0.80

1.2

1.1

—

Any death

215

0.72

0.80

1.1

—

Thyroiditis

1.73

0.79

1.1

—

Other diseases of the digestive system

164

1.40

0.79

1.2

1.1

—

Mental retardation, excluding more controls

0.00

0.79

0.0

1.1

—

Other or unspecified ileus, impaction or obstruction

1.72

0.79

1.2

1.1

—

Hyperprolactinaemia

1.82

0.79

1.0

1.1

—

Benign neoplasm: Caecum

1.82

0.79

1.5

1.1

—

Non-invasive ventilation

178

1.36

0.79

1.0

1.2

—

Myocarditis

1.82

0.79

1.0

1.1

—

Colonic or urogenital fistula

207

1.35

0.79

1.3

1.1

—

Persistent mood disorders

156

1.41

0.78

1.3

1.1

—

Schizophrenia

150

0.60

0.78

1.0

1.1

—

Hyperplasia of prostate

1.52

0.78

1.1

1.0

—

LSIL lesion of the cervix uteri

187

0.64

0.78

1.2

1.1

—

Malignant neoplasm of skin, including Hilmo

197

0.71

0.77

1.3

1.1

—

Type 1 diabetes, strict (exclude DM2)

124

0.56

0.77

1.1

1.2

—

Colon adenocarcinoma, helper endpoint

0.00

0.77

0.0

1.1

—

Other bacterial diseases

530

1.17

0.77

1.1

—

Caries of dentine, including avohilmo

314

1.20

0.77

1.1

1.2

—

Recurrent aphthous stomatitis , including avohilmo

115

1.48

0.76

1.1

—

Enterobiasis, including avohilmo

1.77

0.76

1.3

1.0

—

Other specified/unspecified inflammatory spondylopathies

1.77

0.76

1.3

1.1

—

Episcleritis

1.77

0.76

1.0

1.1

—

Biological medication for rheuma

200

1.35

0.76

1.1

—

Use of disulfiram, acamprosate or naltrexone

1.70

0.75

1.0

1.1

—

Nephropathy related operations

1.70

0.75

1.4

1.1

—

Congenital malformations, deformations and chromosomal abnormalities, including avohilmo

683

1.17

0.75

1.2

1.1

—

Otitis media, unspecified

106

1.48

0.75

1.2

—

Substance use, excluding alcohol

209

1.34

0.75

1.3

1.1

—

Phobic anxiety disorders

183

1.36

0.74

1.2

1.1

—

Osteomyelitis

2.09

0.74

1.6

1.0

—

Artificial joint operation, meniscal resection

396

1.19

0.74

1.1

—

Distal bite

2.07

0.74

1.0

1.3

—

Abnormal findings in secretions and smears from cervix uteri vagina vulva

484

1.19

0.74

1.1

—

184

1.36

0.73

1.2

1.1

—

Ménière disease

1.84

0.73

1.0

—

Mixed conductive and sensorineural hearing loss

1.84

0.73

1.7

1.1

—

Disorder of lipoprotein metabolism, unspecified

1.84

0.73

1.1

—

Cholecystectomy

482

1.20

0.73

1.1

—

Erysipelas

279

1.27

0.73

1.1

—

Other blood glucose lowering drugs, excl. Insulins

1.64

0.73

1.1

—

Deep endometriosis

108

1.48

0.73

1.1

—

Other puerperal infections

150

1.40

0.73

1.3

1.1

—

Left ventricular outflow tract obstruction, narrow definition

2.00

0.72

1.0

—

Amiodarone users

2.00

0.72

1.0

—

Assault by bodily force

1.52

0.72

1.1

—

Bipolar affective disorders

211

1.33

0.71

1.1

—

Melanocytic naevi of other and unspecified parts of face

1.75

0.71

1.0

1.1

—

Injury of nerves at wrist and hand level

1.93

0.70

1.0

1.1

—

Venous thromboembolism

297

1.26

0.70

1.1

—

Cardiac arrhythmias

453

1.17

0.70

1.1

1.2

—

Other (seronegative) rheumatoid arthritis, wide

101

1.49

0.70

1.0

1.1

—

Struck by thrown, projected or falling objec

1.71

0.70

1.6

1.1

—

Benign neoplasm of bone and articular cartilage

1.55

0.69

1.3

1.0

—

Gonarthrosis, primary, with knee surgery

178

1.31

0.69

1.0

1.1

—

Diseases of oral cavity, salivary glands and jaws

199

1.24

0.69

1.0

1.1

—

Haemorrhage in early pregnancy

353

1.24

0.69

1.3

1.1

—

Long labour

338

0.78

0.69

1.1

—

Non-allergic asthma (mode), excluding more controls

117

1.44

0.68

1.1

—

Other diseases of pancreas

1.85

0.68

1.0

1.1

—

Hyperfunction of pituitary gland

1.67

0.68

1.0

1.1

—

Personal history of other diseases and conditions

156

0.64

0.68

1.1

—

Other peripheral vertigo

1.67

0.68

1.4

1.0

—

Valvular operations

1.67

0.68

1.0

—

GI-bleeding

161

1.37

0.68

1.2

1.1

—

Mental and behavioural disorders due to psychoactive substance use

475

1.20

0.67

1.2

1.1

—

Maternal care for known or suspected malpresentation of fetus

268

0.77

0.67

1.4

1.1

—

Emotional disorders and disorders of social functioning with onset specific to childhood

1.59

0.66

1.0

1.2

—

Non-allergic asthma (mode)

118

1.43

0.66

1.1

—

Pure hypercholesterolaemia

288

1.21

0.66

1.3

1.1

—

Other gastritis (incl. Duodenitis)

111

1.44

0.65

1.3

1.1

—

Heart failure and bmi 25plus

1.51

0.65

1.1

1.0

—

Endometriosis of ovary

169

1.34

0.65

1.0

1.2

—

Other infectious diseases, including avohilmo

1.59

0.65

1.0

—

Poisoning by drugs, medicaments and biological substances

277

1.26

0.65

1.1

—

Gout, FINNGEN

1.50

0.64

1.1

1.0

—

Atrophic disorders of skin

127

0.63

1.1

—

Disorders of lipoprotein metabolism and other lipidaemias

344

1.18

0.63

1.2

1.1

—

Alcohol abuse, main dg, excluding more controls

112

1.43

0.63

1.4

1.1

—

Use of donepezil

1.70

0.63

1.0

1.1

—

Paroxysmal tachycardia

157

1.32

0.63

1.0

1.1

—

Type 1 diabetes, strict definition, subgroup 1

102

0.59

0.62

1.2

—

Sequelae of injuries of lower limb

1.55

0.62

1.0

—

Sequelae of injuries of upper limb

1.55

0.62

1.1

1.0

—

Heartburn

1.55

0.62

1.0

1.1

—

Aneurysms, operations, SAH

1.55

0.62

1.0

1.1

—

Superficial injury of head

190

1.31

0.62

1.6

1.1

—

LSIL lesion of the cervix uteri, vagina or vulva

211

0.71

0.62

1.4

1.1

—

Female infertility

236

1.22

0.61

1.2

1.1

—

Unspecified fall

407

1.21

0.61

1.2

1.1

—

Other viral diseases, not elsewhere classified, including avohilmo

322

1.23

0.61

1.2

1.1

—

Cervicocranial syndrome

1.59

0.61

1.1

—

Disorders of tooth development and eruption

133

1.35

0.61

1.1

1.2

—

Congenital deformities of feet, including avohilmo

1.67

0.61

1.0

—

Benign lipomatous neoplasm of other sites/unspecified

1.67

0.61

1.0

—

Type 1 diabetes, strict definition

105

0.57

0.61

1.2

—

Lack of expected normal physiological development

0.00

0.61

0.0

1.2

—

Metabolic disorders

514

1.14

0.61

1.2

1.1

—

Inflammatory bowel disease, strict (require KELA)

256

0.74

0.61

1.1

—

Mental retardation

0.00

0.60

0.0

1.1

—

Malignant neoplasm of mesothelium and soft tissue, including Hilmo

0.00

0.60

0.0

1.1

—

Rash and other nonspecific skin eruption

1.57

0.60

1.4

1.0

—

Sequelae of injuries, of poisoning and of other consequences of external causes

200

1.30

0.60

1.0

1.1

—

UC patients in KELA-register (code 208), prior to 1994

0.00

0.60

0.0

1.0

—

Mental retardation, wide definition

0.00

0.60

0.0

1.1

—

IBD patients in KELA-register

255

0.74

0.59

1.1

—

Female infertility, associated with anovulation

148

1.35

0.59

1.2

1.1

—

Open wound of hip and thigh

0.00

0.59

0.0

1.0

—

Benign neoplasm of other and unspecified female genital organs

0.00

0.59

0.0

1.0

—

Other and unspecified rosacea

1.53

0.59

1.2

1.1

—

Delivery

247

0.81

0.59

1.1

1.2

—

False labour

320

1.18

0.59

1.4

1.1

—

Carbimazole or st.post thyroidectomy, condition for graves disease

192

1.30

0.59

1.2

1.1

—

Presence of cardiac and vascular implants and grafts

120

0.67

0.59

1.0

1.1

—

Rosacea

114

1.40

0.58

1.4

1.1

—

Pedal cyclist injured in collision with motor vehicle

0.00

0.58

0.0

1.0

—

Other surgical follow-up care

0.00

0.58

0.0

1.0

—

Secondary uncertain malignant neoplasm

1.51

0.58

1.0

1.1

—

DVT of lower extremities and pulmonary embolism

218

1.28

0.58

1.0

1.1

—

Rheumatoid arthritis

170

1.30

0.58

1.0

1.2

—

Acute gastritis

1.72

0.57

2.0

1.1

—

Ovarian cyst

243

1.20

0.57

1.1

—

Other benign neoplasms of connective and other soft tissue

1.48

0.57

1.1

1.0

—

Adjustment and management of implanted device

1.48

0.57

1.0

—

Single delivery by caesarean section

203

0.79

0.57

1.3

1.2

—

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

202

1.29

0.57

1.1

—

Congenital malformations, deformations and chromosomal abnormalities

670

1.15

0.56

1.2

1.1

—

Open wound of head

368

1.20

0.56

1.1

—

Varicose veins

267

0.79

0.56

1.2

1.1

—

Other/unspecified synovitis and tenosynovitis

1.51

0.56

1.0

1.1

—

Contusion of other and unspecified parts of foot

1.46

0.56

1.1

—

Acute lymphadenitis

1.46

0.56

1.0

1.1

—

Abnormal results of function studies

1.46

0.56

1.1

—

Hypokalaemia

1.46

0.56

1.3

1.1

—

Superficial injury of ankle and foot

150

1.33

0.55

1.5

1.1

—

Other obstructed labour

0.55

1.0

1.1

—

Ingrowing nail

1.62

0.55

1.0

—

Artrosis, including avohilmo

442

1.14

0.55

1.1

—

Endometriosis diagnosis and infertility diagnosis occurring together

159

1.32

0.55

1.1

—

Poisoning by medicine

257

1.25

0.55

1.2

1.1

—

Gout

1.45

0.55

1.1

—

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly, including avohilmo

155

0.69

0.54

1.2

1.1

—

Emotional disorders starting during childhood or adolecense, excluding more controls

1.50

0.54

1.0

1.2

—

Other coagulation defects

1.50

0.54

1.1

—

Fibroblastic disorders

1.41

0.54

1.1

—

COPD, hospital admissions 3, with asthma pneumonia sepsis

1.50

0.53

1.0

—

Sequelae with surgical and medical care as external cause

125

1.36

0.53

1.0

1.1

—

Contact with and exposure to communicable diseases

457

0.83

0.53

1.1

1.2

—

Diseases of peritoneum

1.54

0.53

1.2

1.0

—

Palmar fascial fibromatosis [Dupuytren]

1.54

0.53

1.0

—

Problems related to lifestyle

108

1.39

0.53

1.0

1.1

—

Transplanted organ and tissue status

1.45

0.53

1.3

1.1

—

Gastric ulcer

1.45

0.53

1.1

1.0

—

Emotional disorders starting during childhood or adolescence

1.44

0.52

1.0

1.1

—

Ankylosing spondylitis, ICD10

1.52

0.52

1.1

1.0

—

Deforming dorsopathies

187

1.28

0.52

1.1

—

malignant neoplasm of female genital organs, including Hilmo

0.62

0.52

1.0

1.1

—

Seborrhoeic keratosis

117

1.37

0.52

1.0

1.1

—

Retained placenta and membranes, without haemorrhage

132

0.68

0.51

1.2

1.1

—

Exclusions for E4_PCOS_CONSORTIUM

549

1.13

0.51

1.3

1.1

—

Unspecified abortion

1.50

0.51

1.0

1.1

—

Benign neoplasm: salivary glands, exclude unknown (D119)

1.50

0.51

1.2

1.1

—

Kela-code for severe mental illness

381

0.81

0.51

1.0

1.1

—

Nonischemic cardiomyopathy

1.50

0.51

1.0

1.1

—

Nonsuppurative otitis media

264

1.22

0.51

1.1

1.2

—

Perforation of tympanic membrane

1.41

0.51

1.2

1.1

—

Injuries to the elbow and forearm

604

0.86

0.51

1.1

1.2

—

Delivery, wide proxy

215

0.81

0.51

1.1

1.2

—

In situ neoplasms

296

1.22

0.51

1.0

1.1

—

Calcific aortic valvular stenosis

1.50

0.50

1.0

—

Calcific aortic valvular stenosis, operated

1.50

0.50

1.0

—

Operations 2 for CAVS

1.50

0.50

1.0

—

Calcific aortic valvular stenosis, diagnosis (helper)

1.50

0.50

1.0

—

Effects of foreign body entering through natural orifice

206

1.26

0.50

1.3

1.1

—

Postmenopausal atrophic vaginitis

0.68

0.50

1.1

—

Scoliosis

1.39

0.50

1.0

1.1

—

Calcific aortic valvular stenosis, including rheumatic fever

1.50

0.50

1.0

—

Secondary and unspecified malignant neoplasm of lymph nodes

1.46

0.50

1.0

1.1

—

Benign neoplasm of major salivary glands

1.46

0.50

1.2

1.0

—

Other and unspecified injuries of head

1.46

0.50

1.2

1.0

—

Other noninflammatory disorders of uterus, except cervix

0.65

0.50

1.0

1.2

—

Substance abuse

473

1.16

0.49

1.2

1.1

—

Nonalcoholic fatty liver disease

1.49

0.49

1.0

—

Other bacterial intestinal infections, including avohilmo

180

1.28

0.49

1.4

1.1

—

Ulcerative colitis (strict definition, all Crohn cases excluded)

144

0.69

0.49

1.0

1.1

—

Chondropathies

136

1.32

0.49

1.0

1.1

—

Impacted maxillary molar

107

0.65

0.48

1.0

1.1

—

Iron deficiency

1.52

0.48

1.1

—

Injury of unspecified body region

1.52

0.48

1.3

1.1

—

Pedal cyclist injured in transport accident

223

0.76

0.48

1.0

1.1

—

Achilles tendinitis

1.52

0.48

1.1

—

Lesion of ulnar nerve

1.40

0.48

1.1

—

Gonarthrosis,primary

301

1.16

0.48

1.1

—

Acute renal failure

1.45

0.48

1.0

1.1

—

Other congenital malformations, including avohilmo

143

0.70

0.47

1.6

1.1

—

Type of accident

267

0.79

0.47

1.1

—

Schizophrenia or delusion

333

0.81

0.47

1.1

—

Arthropod-borne viral fevers and viral haemorrhagic fevers, including avohilmo

128

1.33

0.47

1.2

1.1

—

Malignant neoplasm of prostate

0.58

0.47

1.0

1.1

—

Other heart diseases

350

1.15

0.47

1.1

1.2

—

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.46

0.46

1.3

1.0

—

Ulcer of lower limb, not elsewhere classified

1.46

0.46

1.3

1.1

—

Sleep disorders (combined)

123

582

1.10

0.46

1.1

1.2

—

Perineal laceration during delivery

277

0.82

0.46

1.1

—

Redundant prepuce, phimosis and paraphimosis

118

1.33

0.46

1.0

1.2

—

Coxarthrosis, primary, with hip surgery

153

0.73

0.46

1.1

—

Haemangioma, any site

1.43

0.46

1.0

—

Benign neoplasm: Skin of other and unspecified parts of face

1.43

0.46

1.0

—

Contact with machinery

1.43

0.46

1.0

1.1

—

Postpartum hemorraghe, parous women as controls

323

0.83

0.45

1.2

1.1

—

Open wound of forearm

0.62

0.45

1.2

1.1

—

Basal cell carcinoma

136

0.75

0.45

1.4

1.1

—

Other malignant neoplasms of skin (=non-melanoma skin cancer)

143

0.76

0.45

1.4

1.1

—

Schizophrenia, schizotypal and delusional disorders

331

0.82

0.45

1.1

—

Gestational [pregnancy-induced] oedema and proteinuria without hypertension

0.59

0.45

1.2

1.1

—

Maternal care for other conditions predominantly related to pregnancy

338

1.18

0.45

1.2

1.1

—

Dysplasia of cervi uteri

230

1.19

0.45

1.1

—

Seronegative rheumatoid arthritis

1.40

0.45

1.0

1.1

—

Diseases of salivary glands

292

1.20

0.45

1.2

1.1

—

Congenital malformations of cardiac septa

1.38

0.44

1.0

1.1

—

Other appendicitis

1.37

0.44

1.0

—

Coxarthrosis, primary

210

0.79

0.44

1.1

—

Other superficial mycoses, including avohilmo

130

1.31

0.43

1.2

1.1

—

COPD related to multimorbidity

108

0.70

0.43

1.0

1.1

—

All chronic kidney diseases

297

0.83

0.43

1.2

1.1

—

Fracture of foot, except ankle

266

1.20

0.43

1.4

1.1

—

Other and unspecified follicular disorders

1.61

0.43

1.0

—

Use of pramipexole

104

1.35

0.43

1.1

—

Other infectious diseases

1.61

0.43

1.0

1.1

—

Other diseases of biliary tract

1.61

0.43

1.4

1.1

—

Bacterial pneumonia (organism specified)

274

1.19

0.42

1.1

—

Temporomandibular joint disorders, including avohilmo

583

1.13

0.42

1.2

—

Fracture of femur

0.64

0.42

1.0

1.1

—

Papulosquamous disorders

285

1.19

0.42

1.3

1.1

—

Eustachian salpingitis and obstruction

0.64

0.42

1.3

1.1

—

Procreative management

318

1.17

0.42

1.2

1.1

—

Inflammatory disorders of breast

1.38

0.42

1.3

1.1

—

Fracture of forearm

449

0.86

0.42

1.2

—

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

1.40

0.42

1.0

1.1

—

Post-traumatic stress disorder

131

1.30

0.42

1.0

1.1

—

Other predominantly sexually transmitted diseases, not elsewhere classified, including avohilmo

313

1.18

0.42

1.1

—

Bacterial pneumoniae

250

1.19

0.42

1.1

—

Diseases of pulp and periapical tissues and dental caries

240

1.15

0.42

1.1

1.2

—

Mouth breathing

283

0.81

0.41

1.1

—

Degenerative diseases of the nervous system

1.41

0.41

1.2

1.0

—

Diseases of arteries, arterioles and capillaries

256

1.17

0.41

1.2

1.1

—

Abnormal serum enzyme levels

118

1.31

0.41

1.3

1.1

—

Other assisted single delivery

1.52

0.41

1.0

—

Nontoxic single thyroid nodule

1.52

0.41

1.8

1.1

—

Clear cell adenocarcinoma of kidney

0.00

0.41

0.0

1.1

—

Disorders in reading

0.00

0.41

0.0

1.2

—

malignant neoplasm of male genital organs

0.68

0.41

1.0

1.1

—

Pollen allergy

264

1.20

0.40

1.1

—

Anomalies of dental arch relationship, including avohilmo

216

0.79

0.40

1.1

—

Enteropathic arthropathies

0.00

0.40

0.0

1.1

—

1.35

0.40

1.1

—

Atrial septal defect, secundum type

0.00

0.40

0.0

1.1

—

L02BB Anti-androgens

0.00

0.40

0.0

1.1

—

Chronic gastritis

114

1.32

0.40

1.3

1.1

—

Carpal tunnel syndrome

413

0.86

0.40

1.1

1.2

—

Contact with sharp glass

1.47

0.40

1.4

1.0

—

Generalized epilepsy

1.47

0.40

1.0

—

Dislocation, sprain and strain of joints and ligaments of head

1.47

0.40

1.0

—

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Aquaporin 4 water channel IgG Ab [Presence] in Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS