Congenital deformities of hip

Q17_CONGEN_DEFORMITI_HIP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q65
  • Cause of death: ICD-10 Q65

2 out of 7 registries used, show all original rules.

779

4. Check minimum number of events

None

779

5. Include endpoints

None

779

6. Filter based on genotype QC (FinnGen only)

701

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Deformitates congenitae coxae

Similar endpoints

List of similar endpoints to Congenital deformities of hip based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17520 12354 5155
Only index persons 11084 7907 3177
Unadjusted period prevalence (%)
Whole population 0.29 0.35 0.14
Only index persons 0.24 0.29 0.12
Median age at first event (years)
Whole population 0.08 0.05 0.06
Only index persons 0.13 0.10 0.18

-FinnGen-

Key figures

All Female Male
Number of individuals 701 569 132
Unadjusted period prevalence (%) 0.18 0.20 0.06
Median age at first event (years) 26.41 27.72 20.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
739
Matched controls
7374
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
+∞
286.5
256
*
NF1AA
NOMESCO Finland
Hip X-ray examination
16.4
211.1
200
163
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
423.5
140.8
137
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
77.1
129.6
70
10
Q65.1
ICD-10 Finland
Congenital dislocation of hip, bilateral
+∞
125.6
117
*
Q65.88
ICD-10 Finland
Other congenital deformities of hip
+∞
124.5
116
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
10.5
114.8
139
159
M16.1
ICD-10 Finland
Other primary coxarthrosis
9.7
114.1
149
188
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
22.9
112.3
84
41
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
13.7
112.1
111
94
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
+∞
110.1
103
*
L13
ICPC
Hip symptom/complaint
6.0
109.5
257
604
Q65.80
ICD-10 Finland
Congenital dysplastic hip or acetabulum, unilateral
1203.9
109.2
104
*
Q65.81
ICD-10 Finland
Congenital dysplastic hip or acetabulum, bilateral
+∞
98.1
92
*
NF1DA
NOMESCO Finland
X-ray of hips
19.1
80.8
65
37
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
10.0
77.6
94
106
NFF25
NOMESCO Finland
Cleaning of hip joint, arthroscopic
93.8
69.4
76
9
Q65.3
ICD-10 Finland
Congenital subluxation of hip, unilateral
+∞
64.5
61
*
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
23.9
59.2
43
19
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
7.6
58.7
89
131
NFG00
NOMESCO Finland
Arthroplasty of hip joint
315.3
58.1
58
*
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
112.4
57.7
62
6
NFE15
NOMESCO Finland
Plastic repair of capsule or ligament of hip joint
601.4
57.4
56
*
M16.2
ICD-10 Finland
Coxarthrosis resulting from dysplasia, bilateral
589.7
56.3
55
*
7543A
ICD-9 Finland
Certain congenital musculoskeletal deformities, Congenital dislocation of hip[LUXATIO COXAE CONGENITA]
508.9
48.9
48
*
Q65.6
ICD-10 Finland
Unstable hip
+∞
47.4
45
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
11.1
46.8
51
49
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.2
43.4
60
79
Q65.2
ICD-10 Finland
Congenital dislocation of hip, unspecified
+∞
36.7
35
*
75560
ICD-8 Finland
Other congenital anomalies of limbs, Dislocatio congenita coxae (fixata)
362.9
35.2
35
*
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
91.6
32.0
35
*
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
34.1
30.2
39
12
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
30.0
30.1
40
14
N02AX02
ATC
tramadol; systemic, rectal
2.5
29.7
275
1415
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.6
29.3
38
46
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
10.7
29.0
32
31
NEK99
NOMESCO Finland
Other operation on bone of pelvis
107.5
28.8
31
*
B01AB05
ATC
enoxaparin; parenteral
2.6
28.3
206
942
L89
ICPC
Osteoarthrosis of hip
7.9
27.3
38
50
L28
ICPC
Limited function/disability (L)
3.0
27.1
140
533
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
11.1
27.0
29
27
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
6.7
26.6
43
67
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
5.5
26.3
53
103
ZXA00
NOMESCO Finland
Right side
2.7
26.3
178
782
N03AX16
ATC
[U] pregabalin
2.7
25.5
160
675
ZXA05
NOMESCO Finland
Left side
2.7
24.2
161
698
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
128.9
23.7
25
*
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
37.6
23.1
29
8
Q65.9
ICD-10 Finland
Congenital deformity of hip, unspecified
+∞
23.0
22
*
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
7.4
23.0
34
48
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
53.7
22.2
26
5
9165
FHL
Removal of osteosynthesis material
9.2
21.2
26
29
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
17.2
21.1
33
20
R5110, ,
SPAT
3.6
20.3
70
207
NFC00
NOMESCO Finland
Exchange of a loose part of prosthesis in hip joint
107.7
19.6
21
*
NFK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of femur
32.2
19.3
25
8
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
5.8
19.3
36
65
NEU20
NOMESCO Finland
Removal of internal fixation device from pelvis
+∞
18.8
18
*
WX130
NOMESCO Finland
Interpleural anesthesia
102.5
18.6
20
*
B01AF01
ATC
rivaroxaban; oral
3.3
18.3
73
237
A28
ICPC
Limited function/disability NOS
2.7
18.0
104
416
R4110
NOMESCO Finland
Physiotherapy
2.1
17.8
216
1202
75561
ICD-8 Finland
Other congenital anomalies of limbs, Praeluxatio congenita coxae (non fixata, fenomeno Ortolani positivo)
97.2
17.6
19
*
M25.5
ICD-10 Finland
Pain in joint
2.0
17.4
279
1714
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
17.1
245
1445
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
16.9
56
161
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.1
16.6
75
262
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
12.5
16.4
29
24
M01AH01
ATC
celecoxib; oral
2.6
16.4
106
448
7152E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,LONKKANIVEL]
61.3
15.8
18
*
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
17.6
15.7
24
14
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
15.3
102
437
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
15.3
200
1134
B01AX06
ATC
[U] rivaroxaban
12.2
14.6
26
22
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
14.6
14
*
Q65.82
ICD-10 Finland
Congenital anterversion of the collum femoris
+∞
14.6
14
*
9402
FHL
Plastering in the operating room and possible repositioning
+∞
14.6
14
*
Q65.4
ICD-10 Finland
Congenital subluxation of hip, bilateral
+∞
14.6
14
*
NFA30
NOMESCO Finland
Exploration of hip joint, arthroscopic
81.6
14.6
16
*
WX320
NOMESCO Finland
Spinalanesthesy
2.2
14.4
149
772
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
5.6
14.1
27
50
M91.2
ICD-10 Finland
Coxa plana
+∞
13.6
13
*
Q65.5
ICD-10 Finland
Congenital subluxation of hip, unspecified
+∞
13.6
13
*
M76.1
ICD-10 Finland
Psoas tendinitis
34.7
13.5
17
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
13.5
71
270
S70.0
ICD-10 Finland
Contusion of hip
4.0
12.7
37
97
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
12.6
96
436
9321
FHL
The first reartroplast due to detachment, also includes the treatment of a fracture due to detachment
+∞
12.5
12
*
NF1AA, ,
SPAT
3.5
12.0
42
125
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
11.8
166
957
N02AA05
ATC
oxycodone; systemic
2.5
11.7
81
352
M76.0
ICD-10 Finland
Gluteal tendinitis
4.9
11.7
26
55
S73.1
ICD-10 Finland
Sprain and strain of hip
12.8
11.7
20
16
SPAT1216
SPAT
Assessment of functional ability
2.3
11.6
91
419
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
11.5
291
2004
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
5.8
11.5
21
37
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.5
11.5
28
64
TNF31
NOMESCO Finland
Prefabricated orthosis, hip or thigh
+∞
11.5
11
*
9964A
ICD-9 Finland
Complications peculiar to certain specified procedures, Mechanical complication of internal orthopaedic device, implant and graft
+∞
11.5
11
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
11.4
161
929
NE1AA, ,
SPAT
5.8
11.0
20
35
A02BC05
ATC
esomeprazole; systemic
1.8
11.0
226
1464
71300
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) coxae
43.9
10.9
13
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
43.9
10.9
13
*
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.2
10.6
43
141
M01AH05
ATC
etoricoxib; oral
1.7
10.6
375
2811
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
9.3
10.5
21
23
Q65.8
ICD-10 Finland
Other congenital deformities of hip
+∞
10.4
10
*
L29
ICPC
Musculoskeletal sympt/complt other
2.4
10.4
77
346
SPAT1229
SPAT
Assessment of need for aid
3.3
10.2
39
123
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.2
10.2
86
408
M01AH02
ATC
rofecoxib; oral
2.6
9.8
58
234
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
10.8
9.8
18
17
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.1
9.6
94
474
M01AB05
ATC
diclofenac; systemic, rectal
1.6
9.4
360
2721
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
30.4
9.4
12
*
Z50.1
ICD-10 Finland
Other physical therapy
3.3
9.4
36
114
NFC99
NOMESCO Finland
Other secondary prosthetic replacement in hip joint, other or unspecified
+∞
9.4
9
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.7
9.3
50
192
M79.6
ICD-10 Finland
Pain in limb
1.6
9.1
306
2236
N03AX12
ATC
[U] gabapentin; oral
2.1
9.0
90
456
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.0
351
2656
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
8.7
58
248
J01FF01
ATC
clindamycin; systemic
1.8
8.6
157
973
M41.9
ICD-10 Finland
Scoliosis, unspecified
4.8
8.6
19
40
R4110, ,
SPAT
2.0
8.4
89
462
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.8
8.4
42
156
Q65
ICD-10 Finland
Congenital deformities of hip
+∞
8.3
8
*
9403
FHL
Adductorotomy
+∞
8.3
8
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
8.3
227
1568
L08
ICPC
Shoulder symptom/complaint
1.8
8.3
143
872
WX212
NOMESCO Finland
Femoral plexus blockade
4.8
8.1
18
38
NE1BG, ,
SPAT
3.8
8.1
24
64
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
8.0
68
323
A02BC02
ATC
pantoprazole; systemic
1.6
8.0
372
2906
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.8
8.0
127
755
S18
ICPC
Laceration/cut
1.6
8.0
295
2189
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
3.8
7.9
24
65
WX402
NOMESCO Finland
General anaesthesia
1.7
7.9
174
1136
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
7.8
189
1265
NF2AT, ,
SPAT
45.4
7.7
9
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.7
7.5
39
148
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.8
7.4
37
137
M01AX17
ATC
nimesulide; oral
1.9
7.4
96
534
NF1BA, ,
SPAT
8.5
7.3
15
18
R60.9
ICD-10 Finland
Oedema, unspecified
3.0
7.3
32
110
WX002
NOMESCO Finland
Sedation and analgesia
1.8
7.3
108
627
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
7.3
7
*
Q65.83
ICD-10 Finland
Congenital coxa whale
+∞
7.3
7
*
9406
FHL
Pelvic osteotomy
+∞
7.3
7
*
M01AE02
ATC
naproxen; oral, rectal
1.5
7.3
448
3690
NFH30
NOMESCO Finland
Reduction of dislocation prosthesis of hip joint, closed
15.9
7.2
11
7
SPAT1153
SPAT
Removal of sutures
1.7
7.2
160
1044
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
30.3
7.2
9
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.1
233
1672
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
7.1
66
326
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.0
582
5109
M01AB55
ATC
diclofenac, combinations; oral
2.9
6.9
31
108
Z3226
NOMESCO Finland
Physiotherapist
1.7
6.9
133
834
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.3
6.8
50
224
9407
FHL
Osteotomy of the upper femur
40.3
6.8
8
*
R5130, ,
SPAT
40.3
6.8
8
*
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
3.5
6.7
23
68
M05BA04
ATC
alendronic acid; oral
2.7
6.6
34
128
B01AB04
ATC
dalteparin; parenteral
3.0
6.6
29
100
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.6
6.6
37
146
N02CC05
ATC
almotriptan; oral
2.6
6.6
38
152
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
6.6
30
106
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
6.6
69
357
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.1
6.5
27
90
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
6.5
69
358
M16.5
ICD-10 Finland
Other post-traumatic coxarthrosis
70.3
6.4
7
*
Q66.9
ICD-10 Finland
Congenital deformity of feet, unspecified
70.3
6.4
7
*
M01AH03
ATC
valdecoxib; oral
2.9
6.3
29
103
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
18.2
6.3
9
5
9341
FHL
Reduction and plaster or plaster exchange
+∞
6.3
6
*
9322
FHL
Subsequent reartroplast due to detachment also includes treatment of the fracture due to detachment
+∞
6.3
6
*
NF1CB
NOMESCO Finland
Hip artrography with X-ray
+∞
6.3
6
*
NFK70
NOMESCO Finland
Bone transport operation of femur
+∞
6.3
6
*
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.1
129
829
M41.4
ICD-10 Finland
Neuromuscular scoliosis
12.6
6.1
10
8
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
6.1
44
196
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.3
6.1
43
190

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
290
1903
1.86
14.20
3.4
2.5
—
—
—
0
0
235
1473
1.87
13.09
3.4
2.5
—
—
—
0
0
380
2792
1.74
12.10
3.8
2.9
—
—
estimate
—
0
0
286
1979
1.72
11.01
7.1
8.1
1.11
1.12
inr
0.15
230
1655
428
3336
1.67
10.24
5.7
5.7
6.03
6.16
mmol/l
0.76
399
3059
367
2754
1.66
10.15
9.5
8.6
1.22
1.22
mmol/l
1.21
332
2449
332
2491
1.60
8.77
9.3
8.9
1.22
1.22
mmol/l
0.71
312
2334
303
2235
1.60
8.53
5.4
5.5
37.25
37.28
g/l
0.03
282
2125
85
432
2.09
8.46
8.9
10.2
-0.06
0.48
mmol/l
0.63
72
354
85
436
2.07
8.26
8.9
10.1
5.11
5.24
kpa
0.61
79
424
84
436
2.04
7.90
9.0
10.2
7.40
7.41
ph
0.07
37
227
184
1239
1.64
7.34
4.5
3.7
—
—
—
0
0
75
400
1.97
6.55
4.4
4.0
7.40
7.34
ph
2.72
50
293
74
394
1.97
6.49
9.5
10.7
96.40
95.47
%
0.38
68
384
351
2791
1.49
6.45
8.2
6.1
11.85
13.78
umol/l
0.91
328
2622
230
1678
1.53
6.40
2.6
2.5
55.68
62.73
u/l
0.95
209
1569
120
752
1.71
6.22
3.3
2.7
24.30
22.40
%
0.67
114
713
395
3251
1.46
5.89
8.1
7.2
0.67
0.66
%
0.15
369
3086
137
902
1.63
5.87
3.1
2.6
14.27
14.13
umol/l
0.08
128
850
492
4226
1.48
5.86
9.2
6.7
81.99
83.77
u/l
0.35
471
4024
396
3268
1.45
5.77
8.1
7.3
8.23
8.34
%
0.36
372
3110
403
3340
1.45
5.72
7.7
7.0
53.52
54.06
%
0.42
382
3222
129
842
1.64
5.72
3.1
2.5
2.47
2.49
g/l
0.11
119
786
354
2867
1.45
5.67
3.3
2.8
73.71
72.12
nmol/l
0.49
325
2670
299
2346
1.46
5.67
8.1
7.3
—
—
—
0
0
126
824
1.63
5.53
9.3
8.8
1.18
1.21
mmol/l
0.53
119
767
393
3257
1.44
5.49
8.1
7.2
3.07
2.85
%
0.89
368
3089
406
3389
1.43
5.43
7.9
7.1
31.49
31.70
%
0.15
388
3261
97
613
1.67
4.86
6.5
9.0
106.24
105.03
mmol/l
2.01
97
613
79
472
1.75
4.85
4.8
4.4
0.27
0.60
%
1.49
33
136
9
10
9.07
4.78
1.2
1.2
—
—
—
0
0
42
206
2.10
4.65
1.5
1.2
2.27
10.09
u/ml
—
6
33
223
1714
1.43
4.51
2.5
2.5
2.52
2.60
mg/l
0.26
195
1495
445
3843
1.39
4.51
10.5
9.5
3.84
3.81
e9/l
0.13
377
3298
69
409
1.75
4.37
6.1
6.0
59.38
63.53
ng/l
0.24
62
382
273
2188
1.39
4.30
2.0
1.8
98.04
97.18
pmol/l
0.12
149
1159
142
1009
1.50
4.30
1.4
1.4
710.67
572.44
titre
0.30
30
193
80
498
1.68
4.25
9.8
11.5
6.30
6.40
mmol/l
0.08
73
482
83
523
1.66
4.21
8.6
10.2
—
—
—
0
0
77
477
1.68
4.17
5.5
4.9
0.03
0.09
%
0.68
31
125
647
6018
1.58
4.14
17.7
13.1
139.53
139.58
mmol/l
0.29
636
5885
78
486
1.67
4.13
5.6
5.1
0.00
0.09
%
1.03
28
118
90
584
1.61
4.07
1.3
1.4
—
—
—
0
0
188
1425
1.42
4.06
2.6
2.1
230.01
214.56
u/l
0.09
177
1366
140
1006
1.48
4.00
3.8
4.0
755.97
911.39
ng/l
0.36
115
824
96
641
1.57
3.85
1.6
1.6
1025.25
1136.04
nmol/l
0.62
72
499
98
659
1.56
3.82
11.4
11.7
—
—
—
0
0
645
6020
1.54
3.78
17.9
13.1
3.93
3.91
mmol/l
0.93
631
5863
109
752
1.52
3.78
2.2
2.0
—
—
—
0
0
418
3630
1.34
3.78
8.1
7.6
0.21
0.19
e9/l
1.76
361
3174
32
155
2.11
3.70
4.4
4.7
1.45
1.59
%
0.30
27
145
78
501
1.62
3.69
5.5
4.8
0.33
0.84
%
1.49
33
149
206
1610
1.38
3.68
3.0
3.0
100.14
76.95
ng/l
0.09
103
808
31
149
2.12
3.66
2.6
2.1
262.12
173.43
ug/l
0.58
25
136
20
79
2.57
3.64
1.4
1.2
—
—
—
0
0
230
1834
1.36
3.63
3.6
2.8
2.36
2.37
mmol/l
1.08
208
1694
468
4156
1.34
3.51
5.1
4.2
286.63
1865.54
e6/l
—
8
54
95
647
1.53
3.50
8.7
9.8
7.41
7.41
ph
0.85
77
524
675
6386
1.63
3.49
16.7
12.0
18.18
20.86
mg/l
1.96
553
4971
399
3490
1.31
3.20
8.0
7.2
0.55
0.55
e9/l
0.04
341
3011
399
3492
1.30
3.18
8.1
7.2
0.04
0.04
e9/l
0.22
341
3015
181
1417
1.36
3.16
1.7
1.5
19.03
20.29
nmol/l
0.57
158
1241
150
1139
1.39
3.15
1.3
1.3
19.63
9.34
u/ml
0.53
52
431
149
1134
1.39
3.09
3.0
2.9
531.79
537.08
mosm/kgh2o
0.10
135
999
408
3597
1.29
3.01
8.1
7.2
2.08
2.13
e9/l
0.41
359
3191
9
21
4.32
2.99
1.1
2.0
126.23
105.89
ug/l
—
9
21
105
758
1.45
2.92
2.4
2.9
4.09
4.68
e9/l
0.68
92
687
21
95
2.24
2.91
3.3
2.6
—
—
—
0
0
46
276
1.71
2.86
2.4
2.0
0.00
0.01
estimate
0.50
16
108
80
554
1.49
2.75
1.7
1.7
21.20
19.32
iu/l
0.21
63
434
529
4855
1.31
2.73
4.7
4.7
36.44
37.01
mmol/mol
0.82
504
4620
566
5244
1.33
2.72
5.1
4.3
14.54
14.45
pmol/l
0.40
526
4817
80
562
1.47
2.58
3.2
3.2
9.90
9.47
g/l
0.45
74
527
162
1288
1.33
2.52
2.5
2.6
93.27
91.00
ug/g
0.04
127
1024
671
6411
1.48
2.49
18.2
13.4
65.42
66.18
umol/l
0.29
660
6330
144
1128
1.34
2.47
1.8
1.6
—
—
—
0
0
166
1329
1.32
2.45
2.3
2.5
1.29
1.12
mg/l
0.21
125
977
6
12
5.02
2.40
3.8
2.2
—
—
—
0
0
356
3146
1.25
2.35
11.8
10.2
0.00
0.00
e9/l
0.11
277
2515
99
738
1.39
2.32
6.7
8.3
7.37
7.37
ph
0.00
63
459
265
2269
1.26
2.30
1.7
1.7
—
—
—
0
0
117
899
1.35
2.28
2.9
2.2
2.42
2.43
mmol/l
0.40
106
802
20
100
2.02
2.21
7.3
6.2
450.15
400.76
umol/l
0.79
20
92
75
539
1.43
2.17
2.4
1.9
0.00
0.04
estimate
0.78
20
140
29
166
1.77
2.17
2.9
3.0
—
—
—
0
0
243
2079
1.25
2.09
1.7
1.6
1.81
1.87
g/l
0.25
152
1250
18
89
2.04
2.06
1.4
1.3
—
89.19
—
0
7
416
3775
1.23
2.04
3.9
3.3
83.26
62.10
ug/l
2.09
394
3596
95
721
1.36
2.02
6.9
8.4
1.02
1.22
mmol/l
0.28
84
590
237
2030
1.24
2.01
3.8
3.4
32.46
29.51
u/l
0.28
226
1948
622
5917
1.31
1.94
6.0
5.2
1.94
1.84
mu/l
0.43
596
5615
6
16
3.76
1.93
1.2
1.3
—
—
—
0
0
449
4122
1.22
1.91
3.7
3.3
33.22
31.76
u/l
0.20
431
3959
9
34
2.66
1.86
2.4
3.6
—
—
—
0
0
129
1036
1.29
1.86
3.8
3.2
3.33
3.79
e6/l
0.23
63
497
93
716
1.34
1.81
1.4
1.5
—
—
—
0
0
219
1881
1.23
1.78
3.6
2.5
—
—
—
0
0
25
146
1.73
1.78
1.3
1.5
27.39
17.17
u/l
0.60
19
125
76
569
1.37
1.77
1.5
1.6
—
—
—
0
0
201
1717
1.23
1.72
3.7
3.4
0.34
0.33
e6/l
0.03
144
1219
19
103
1.86
1.72
6.1
3.8
5.59
6.89
pmol/l
0.69
19
103
15
75
2.02
1.69
4.1
5.3
—
—
—
0
0
7
25
2.81
1.65
1.3
3.0
—
—
—
0
0
54
388
1.42
1.61
1.4
1.5
—
—
—
0
0
8
32
2.51
1.59
1.1
1.4
—
—
—
0
0
14
70
2.01
1.59
1.4
1.7
—
—
—
0
0
554
5236
1.22
1.59
4.1
3.8
5.56
5.56
mmol/l
0.04
511
4872
106
849
1.29
1.57
1.3
1.2
—
—
—
0
0
378
3453
1.19
1.56
4.2
3.6
0.00
0.01
estimate
0.80
88
674
227
1983
1.21
1.54
6.7
6.6
—
—
—
0
0
52
375
1.41
1.53
1.1
1.1
—
—
—
0
0
146
1220
1.24
1.53
1.4
1.3
38.08
26.29
iu/ml
0.27
40
344
97
773
1.29
1.50
1.7
1.6
—
—
—
0
0
27
170
1.61
1.50
1.2
1.3
319.70
341.40
ug/g
—
10
88
110
893
1.27
1.48
3.1
3.3
161.80
478.59
ng/l
1.97
64
522
44
310
1.44
1.47
1.7
1.8
5.42
5.45
iu/ml
—
6
66
22
132
1.68
1.46
3.1
1.8
12.29
3.30
ug/l
0.34
16
123
29
188
1.56
1.43
2.9
2.8
2151.75
307.05
e6/l
0.56
20
143
29
188
1.56
1.43
2.8
2.7
44.33
8.47
e6/l
0.59
18
136
21
126
1.68
1.40
1.7
1.5
0.62
0.48
g/l
0.38
16
105
675
6547
1.33
1.40
14.4
10.2
—
—
—
0
0
79
619
1.31
1.40
7.0
4.7
1.58
1.63
%
0.19
71
569
33
222
1.51
1.39
1.8
1.8
—
—
—
0
0
62
470
1.35
1.38
1.2
1.2
—
—
—
0
0
175
1507
1.21
1.37
4.7
3.6
7.39
7.39
ph
0.27
129
1038
35
240
1.48
1.36
5.9
6.1
297.28
369.28
mg/l
0.26
18
139
222
1958
1.19
1.34
4.0
3.5
25.81
50.02
e6/l
1.04
167
1448
150
1276
1.22
1.33
2.9
2.9
9.26
9.01
e6/l
0.06
135
1154
22
136
1.63
1.33
2.2
3.9
34.65
33.52
umol/l
0.12
17
120
9
43
2.10
1.30
1.3
1.2
15.22
7.56
mm/h
—
9
43
9
44
2.05
1.26
1.2
1.3
—
—
—
0
0
86
692
1.27
1.26
1.7
1.5
—
—
—
0
0
129
1088
1.22
1.25
3.6
3.0
1.03
1.06
e6/l
0.05
65
543
62
790
0.76
1.24
1.5
1.6
1107.00
987.12
mu/l
0.30
55
697
260
2337
1.17
1.24
1.6
1.5
1.16
2.50
u/ml
1.21
67
575
13
70
1.87
1.23
1.1
1.2
—
—
—
0
0
31
212
1.48
1.23
1.8
1.8
167.14
122.22
au/ml
—
7
72
18
108
1.68
1.22
2.6
3.8
—
—
—
0
0
659
6390
1.27
1.22
12.9
9.8
23.58
24.46
u/l
0.85
640
6239
5
19
2.64
1.21
1.0
1.1
318.00
328.21
ng/l
—
5
14
5
19
2.64
1.21
1.6
1.3
—
—
—
0
0
5
19
2.64
1.21
1.0
1.1
637.40
553.43
ng/l
—
5
14
38
272
1.42
1.21
1.5
1.8
248.27
188.97
u/ml
0.52
22
134
99
1185
0.81
1.19
4.2
4.3
4.56
23.87
mg/mmol
0.71
57
754
15
86
1.76
1.19
1.8
1.3
—
—
—
0
0
368
3405
1.16
1.18
4.2
3.5
0.00
0.00
estimate
0.50
88
710
717
7042
1.54
1.18
24.8
18.4
89.09
88.95
fl
0.34
710
6976
97
1162
0.81
1.17
3.7
3.6
29.10
60.58
mg/l
1.34
56
771
10
50
2.01
1.16
1.2
1.7
—
—
—
0
0
16
95
1.70
1.13
2.2
3.0
837.55
504.62
e6/l
1.53
11
66
717
7046
1.52
1.13
24.9
18.4
4.48
4.53
e12/l
2.52
702
6871
717
7046
1.52
1.13
24.8
18.3
29.69
29.70
pg
0.08
710
6980
717
7046
1.52
1.13
25.6
19.0
39.61
40.49
%
1.08
710
6978
29
200
1.47
1.12
1.6
2.7
361.48
431.15
mg/l
0.56
29
193
58
452
1.30
1.10
4.0
3.3
4.81
4.72
pmol/l
0.27
50
400
16
96
1.68
1.10
3.5
3.3
—
—
—
0
0
717
7048
1.51
1.10
24.9
18.5
6.69
6.77
e9/l
0.56
702
6863
12
66
1.83
1.08
1.1
1.2
—
—
—
0
0
8
41
1.96
1.08
1.0
1.1
114.69
148.50
iu/ml
—
8
41
35
253
1.40
1.07
3.6
2.5
1.02
1.02
ratio
0.41
29
230
717
7050
1.50
1.07
25.1
18.7
132.28
133.82
g/l
2.45
710
6983
17
105
1.63
1.06
1.1
1.1
—
—
—
0
0
369
3436
1.14
1.04
4.2
3.5
0.00
4.15
estimate
0.80
86
703
233
2102
1.15
1.04
1.8
1.9
—
—
—
0
0
15
90
1.68
1.04
1.7
1.9
13.20
13.13
%
0.10
15
90
19
122
1.57
1.02
4.1
3.5
23.58
23.91
mg/l
0.02
12
84
716
7042
1.47
1.02
25.0
18.5
261.92
266.72
e9/l
1.24
701
6884
201
1797
1.16
1.01
4.3
3.5
0.00
0.00
estimate
1.08
87
672
22
319
0.68
1.00
1.7
1.6
—
—
—
0
0
35
257
1.38
0.99
2.2
2.3
14.45
5.37
ug/l
0.61
25
225
5
23
2.18
0.98
1.0
1.3
—
—
—
0
0
22
317
0.68
0.97
1.6
1.5
—
—
—
0
0
7
36
1.95
0.97
1.1
1.4
—
—
—
0
0
17
108
1.58
0.96
1.1
1.1
—
—
—
0
0
216
1953
1.15
0.93
3.5
2.9
0.00
0.01
estimate
1.34
74
573
6
28
2.15
0.91
1.2
1.9
—
—
—
0
0
84
703
1.22
0.91
1.2
1.3
—
—
—
0
0
239
2184
1.14
0.87
2.0
1.9
1.27
1.32
mmol/l
0.50
216
1941
8
43
1.87
0.87
1.3
1.1
—
—
—
0
0
8
43
1.87
0.87
1.3
1.0
1715.75
1445.72
miu/ml
—
8
43
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
76
637
1.21
0.82
1.2
1.2
—
—
—
0
0
8
46
1.74
0.82
1.8
2.3
1.26
1.19
mmol/l
—
8
46
54
436
1.25
0.82
7.2
3.7
75.26
70.90
e9/l
0.36
40
290
15
97
1.55
0.81
2.9
4.0
383.04
48.26
u/ml
0.41
15
97
26
189
1.39
0.81
5.9
7.2
24.84
23.96
mmol/l
0.64
26
183
107
930
1.17
0.78
1.5
1.6
470.73
33293117.24
pmol/l
1.31
93
820
8
48
1.67
0.78
1.8
2.2
105.75
105.77
mmol/l
—
8
48
8
48
1.67
0.78
1.8
2.2
3.98
3.96
mmol/l
—
8
48
83
707
1.19
0.77
3.3
4.2
5.11
6.20
umol/l
0.71
66
596
6
34
1.77
0.76
1.7
2.3
29.37
15.89
umol/l
—
6
34
19
132
1.45
0.76
3.6
9.7
64.03
65.70
%
0.12
19
132
12
75
1.61
0.74
1.2
1.0
—
—
—
0
0
65
543
1.21
0.74
2.3
2.2
—
—
—
0
0
249
2304
1.12
0.73
2.1
2.3
—
—
—
0
0
21
151
1.40
0.71
1.1
1.2
—
—
—
0
0
34
265
1.29
0.70
3.4
7.4
0.64
0.61
%
0.18
34
265
43
346
1.25
0.69
4.0
4.0
1.87
1.53
ug/l
0.37
37
307
68
576
1.20
0.68
2.2
2.3
39.57
31.51
u/l
0.44
51
470
43
347
1.25
0.68
1.9
1.5
0.17
0.23
mg/l
0.68
13
149
11
69
1.60
0.68
2.6
3.9
1.34
1.74
ratio
—
6
37
272
2540
1.11
0.67
4.0
3.2
0.00
0.02
estimate
1.31
69
576
19
258
0.73
0.65
2.1
1.7
—
—
—
0
0
122
1092
1.14
0.62
3.4
3.0
299.09
306.92
umol/l
0.45
105
1005
5
30
1.67
0.61
1.6
1.0
—
—
—
0
0
47
389
1.22
0.61
2.1
1.8
7.08
9.12
u/l
0.68
35
278
8
52
1.54
0.59
4.1
1.6
31.50
31.17
pg
—
8
52
8
53
1.51
0.58
1.1
1.2
—
—
—
0
0
191
1764
1.11
0.58
1.8
1.8
—
—
—
0
0
6
36
1.67
0.56
1.8
6.5
—
—
—
0
0
20
150
1.34
0.55
2.5
3.5
1.00
3.39
index
—
10
83
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
74
649
1.15
0.52
1.7
1.9
—
—
—
0
0
6
40
1.50
0.51
2.0
4.0
—
60.68
—
0
9
41
342
1.21
0.51
1.2
1.2
1.86
6.66
u/ml
3.49
28
227
297
2817
1.09
0.51
3.6
3.2
6.23
6.27
ph
0.29
179
1517
29
233
1.25
0.51
1.4
1.3
—
—
—
0
0
21
267
0.78
0.49
1.0
1.1
—
0.56
—
0
22
12
84
1.43
0.49
5.1
12.6
11.52
11.84
%
0.13
12
84
40
335
1.20
0.49
5.8
4.1
2.65
7.01
ug/l
1.99
32
256
50
428
1.18
0.48
1.3
1.3
—
—
—
0
0
67
588
1.15
0.48
2.2
2.0
—
—
—
0
0
17
221
0.76
0.47
1.3
1.2
—
—
—
0
0
17
221
0.76
0.47
1.3
1.2
—
—
—
0
0
14
102
1.38
0.47
1.6
1.5
1311.38
13289.39
e6/l
—
8
72
7
48
1.46
0.46
1.0
1.9
—
—
—
0
0
26
209
1.25
0.46
2.4
3.5
6.97
9.84
umol/l
0.44
20
167
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
28
228
1.23
0.45
1.1
1.1
5.47
15.22
au/ml
—
7
45
14
103
1.36
0.45
1.3
1.3
—
—
—
0
0
32
265
1.21
0.44
1.4
1.6
27.06
6.30
u/ml
—
7
62
19
148
1.29
0.43
1.4
1.1
—
—
—
0
0
22
175
1.26
0.43
1.1
1.1
—
—
—
0
0
76
680
1.13
0.42
1.2
1.3
—
—
—
0
0
44
378
1.17
0.42
1.3
1.6
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
—
—
—
0
0
12
87
1.38
0.42
3.3
3.1
35.02
39.30
%
0.66
12
87
0
17
0.00
0.40
0.0
1.4
—
339.25
—
0
12
39
334
1.17
0.39
1.3
1.2
0.41
1.42
u/ml
1.54
24
192
5
35
1.43
0.39
1.0
1.0
—
14.30
—
0
10
25
205
1.22
0.39
2.0
1.9
5.44
4.29
iu/l
0.28
11
85
9
67
1.34
0.38
1.3
2.3
12.71
17.59
umol/l
—
9
61
9
68
1.32
0.37
1.1
1.1
132.67
183.73
mg/l
—
9
61
27
225
1.20
0.37
1.3
1.2
—
—
—
0
0
11
146
0.75
0.36
10.1
7.6
—
—
—
0
0
43
375
1.15
0.36
1.3
1.2
0.72
2.87
u/ml
2.57
27
235
10
133
0.75
0.34
1.1
1.1
60.80
99.79
iu/ml
—
5
39
24
285
0.83
0.34
1.0
1.1
0.88
0.86
g/l
0.14
24
285
6
45
1.33
0.33
1.7
2.4
—
—
—
0
0
11
83
1.33
0.31
1.5
3.4
1.97
1.70
umol/l
0.37
11
78
14
110
1.28
0.31
7.4
3.8
—
—
—
0
0
252
2417
1.06
0.31
5.0
4.2
84.59
83.80
e6/l
0.01
175
1556
7
54
1.30
0.30
2.3
4.8
2.39
2.24
ug/l
—
7
54
7
54
1.30
0.30
1.1
1.2
101.57
108.35
pmol/l
—
7
54
172
1631
1.07
0.30
3.6
3.2
1.02
1.02
kg/l
0.08
114
1044
51
458
1.12
0.29
1.4
1.3
292.74
250.66
miu/ml
0.29
23
238
58
635
0.90
0.28
1.4
1.6
3.32
3.29
mmol/l
0.08
32
421
27
232
1.17
0.28
1.1
1.1
0.27
1.20
u/ml
0.61
16
98
24
204
1.18
0.28
1.4
1.3
—
—
—
0
0
44
393
1.12
0.28
1.2
1.2
—
—
—
0
0
24
279
0.85
0.28
1.0
1.1
1.52
1.57
g/l
0.36
24
279
27
233
1.16
0.27
2.0
2.3
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
582
5883
0.94
0.27
19.4
15.4
332.93
332.96
g/l
0.03
575
5844
72
663
1.09
0.27
1.5
1.4
294.83
383.67
u/ml
0.24
63
618
10
127
0.78
0.26
3.5
3.6
3.28
4.03
e9/l
—
10
127
11
86
1.28
0.26
1.9
1.4
32.37
152.93
mu/l
0.61
11
81
224
2318
0.95
0.25
2.5
2.5
—
—
—
0
0
16
133
1.20
0.24
1.4
2.5
10.29
10.77
mg/l
0.10
16
127
542
5333
1.05
0.23
4.3
4.1
4.65
4.64
mmol/l
0.07
516
5078
544
5355
1.05
0.23
4.6
4.4
2.78
2.75
mmol/l
0.44
516
5086
5
41
1.22
0.22
3.2
2.5
—
—
—
0
0
13
156
0.83
0.22
1.2
1.1
1.24
4.69
eliau/ml
—
5
66
38
343
1.11
0.21
2.0
2.1
—
—
—
0
0
18
209
0.86
0.21
2.9
2.9
53.35
54.66
%
0.20
18
209
502
4936
1.05
0.21
3.7
3.5
1.14
1.18
mmol/l
0.69
469
4651
5
42
1.19
0.21
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
66.00
—
0
11
0
11
0.00
0.21
0.0
1.4
—
4260.83
—
0
6
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
28
248
1.13
0.21
1.2
1.1
18.43
11.14
u/ml
0.49
18
127
8
101
0.79
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.22
0.20
1.5
2.2
—
—
—
0
0
23
202
1.14
0.20
1.9
2.1
—
—
—
0
0
583
5758
1.05
0.19
20.6
15.4
13.45
13.28
%
2.57
577
5700
6
53
1.13
0.18
1.2
1.2
—
—
—
0
0
23
204
1.13
0.17
1.1
1.2
—
—
—
0
0
7
61
1.15
0.17
2.1
1.4
—
—
—
0
0
11
91
1.21
0.17
2.0
2.5
—
—
—
0
0
30
272
1.10
0.16
1.3
1.2
—
—
—
0
0
68
717
0.94
0.16
2.0
1.9
—
—
—
0
0
8
72
1.11
0.16
2.0
2.0
9.35
6.26
u/ml
—
8
72
9
78
1.15
0.15
1.2
1.4
—
—
—
0
0
36
332
1.09
0.15
1.3
1.1
3.47
3.24
u/ml
0.04
23
205
10
118
0.84
0.14
1.0
1.1
—
—
—
0
0
7
90
0.77
0.14
1.1
1.2
—
—
—
0
0
85
811
1.05
0.14
2.3
2.3
1606.20
6909.72
u/l
2.57
22
293
47
499
0.94
0.14
2.8
2.0
6.31
6.29
ph
0.05
26
316
170
1651
1.04
0.13
5.9
4.6
—
—
—
0
0
14
122
1.15
0.13
1.4
2.0
—
—
—
0
0
14
122
1.15
0.13
1.4
2.0
—
—
—
0
0
14
122
1.15
0.13
1.4
2.0
—
—
—
0
0
14
122
1.15
0.13
1.4
2.0
—
—
—
0
0
51
539
0.94
0.13
4.6
3.5
—
—
—
0
0
28
261
1.07
0.09
1.8
1.6
0.21
0.23
g/l
0.50
28
249
74
764
0.96
0.09
1.8
1.8
—
—
—
0
0
64
615
1.04
0.09
1.9
1.8
—
—
—
0
0
6
54
1.11
0.09
1.2
1.4
9.96
13.32
u/ml
—
6
46
29
272
1.07
0.08
1.7
1.6
1.13
1.19
g/l
0.55
29
257
5
60
0.83
0.08
1.0
1.3
36.56
39.50
nmol/l
—
5
52
5
64
0.78
0.08
2.6
1.2
13.21
5.56
u/ml
—
5
59
5
65
0.77
0.08
1.0
1.3
—
194.55
—
0
11
7
67
1.04
0.08
2.4
1.9
—
—
—
0
0
7
68
1.03
0.07
1.0
1.3
—
—
—
0
0
6
70
0.85
0.07
1.0
1.0
—
—
—
0
0
7
82
0.85
0.07
1.0
1.4
0.60
22.60
nmol/l
—
7
77
9
84
1.07
0.07
2.1
2.1
—
—
—
0
0
15
162
0.92
0.06
1.1
1.3
—
—
—
0
0
533
5292
1.02
0.06
4.3
3.9
1.48
1.49
mmol/l
0.24
504
5013
36
344
1.05
0.06
2.3
1.9
11.37
10.27
nmol/l
0.24
31
318
13
141
0.92
0.05
2.2
1.9
—
—
—
0
0
65
633
1.03
0.05
1.5
1.4
—
—
—
0
0
78
763
1.02
0.04
1.9
1.8
—
—
—
0
0
175
1765
0.99
0.04
3.5
3.6
7.69
8.18
mmol/l
0.62
154
1564
75
763
0.98
0.04
1.9
1.8
—
—
—
0
0
26
268
0.97
0.02
1.1
1.1
—
—
—
0
0
157
1578
0.99
0.02
1.9
1.9
—
—
—
0
0
12
127
0.94
0.02
1.0
1.0
—
—
—
0
0
19
197
0.96
0.01
3.1
2.3
0.98
0.73
ug/l
0.44
12
104
46
466
0.98
0.01
2.4
2.3
23.32
13.61
au/ml
—
5
44
23
223
1.03
0.01
1.3
1.5
—
13.66
—
0
7
12
125
0.96
0.00
1.2
1.2
—
—
—
0
0
10
101
0.99
0.00
1.5
1.5
293.50
193.94
pmol/l
—
10
96
69
693
0.99
0.00
1.3
1.3
161.37
145.65
u/ml
0.11
19
259
13
134
0.97
0.00
1.9
1.4
12.00
4.18
u/ml
—
8
80
27
272
0.99
0.00
1.2
1.1
15.84
8.84
u/ml
0.55
17
153
77
768
1.00
0.00
1.9
1.8
—
—
—
0
0
12
116
1.03
0.00
1.1
1.2
2.14
5.02
u/ml
—
7
48
0
9
0.00
0.00
0.0
2.7
—
0.18
—
0
9
0
9
0.00
0.00
0.0
1.0
—
60.44
—
0
9
0
6
0.00
-0.00
0.0
3.3
—
6.90
—
0
6
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
40.62
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
309.13
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
4.29
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
76
0.92
-0.00
3.3
7.9
5.51
6.27
mmol/l
—
7
63
0
6
0.00
-0.00
0.0
1.0
—
0.34
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
484.70
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
3.67
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
1.70
—
0
7

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_DEFORMITI_HIP and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_HIP 1.38 [1.15, 1.65] < 0.001
Birth year 0.992 [0.98, 1.0] 0.083

During the follow-up period (1.1.1998 — 31.12.2019), 242 out of 11663 females with Q17_CONGEN_DEFORMITI_HIP died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_DEFORMITI_HIP 1.696 [1.33, 2.16] < 0.001
Birth year 0.992 [0.98, 1.0] 0.15

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 4808 males with Q17_CONGEN_DEFORMITI_HIP died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_DEFORMITI_HIP.

N-year risk Females Males
1 0.113% 0.388%
5 0.763% 2.236%
10 1.75% 5.465%
15 3.518% 10.243%
20 6.237% 17.495%

Relationships between endpoints

Index endpoint: Q17_CONGEN_DEFORMITI_HIP – Congenital deformities of hip

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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