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Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

Number of people
4 918 (58.76% female)
People with ≥2 records
11.53%
Median duration from first to last measurement
0.93 years

Coding

Definition

OMOP Concept ID
40766800— open in OHDSI Athena.
Part of collection
Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells^^corrected for background with 0 other OMOP concept — open in OHDSI Athena.

OMOP mapping QC

OMOP concept ID Test name Measurement unit (harmonized unit) N people N records Missing measurement value Harmonized value distribution
Test outcome
NA
N
A
AA
L
LL
H
HH
40766800 tb1 — (—) 4836 5463 100.00% Distribution not available
40766800 tb1 iu/ml (iu/ml) 104 118 0.00%

Cohort

Number of people
4 918 (58.76% female)

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

People with ≥2 records
11.53%
Median number of measurements per person
1.0
Median duration from first to last measurement
0.93 years

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

No data available for the distribution of value range per person.

LabWAS

Endpoint
People with measurements
Mean N measurements
Mean measured value
Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
785
551
15.12
307.65
1.1
1.1
1.46
2.16
iu/ml
0.62
18
20
2501
1470
18.50
307.65
1.1
1.1
1.36
2.37
iu/ml
1.51
30
39
1329
1814
7.68
307.65
1.2
1.1
1.61
1.95
iu/ml
0.27
17
38
778
831
9.95
307.65
1.1
1.1
1.46
1.97
iu/ml
0.36
18
17
2376
1206
10.35
307.65
1.1
1.1
2.10
2.28
iu/ml
0.14
32
42
454
392
12.37
307.65
1.1
1.1
2.05
2.70
iu/ml
—
5
5
2315
1510
16.59
307.65
1.1
1.1
1.42
2.47
iu/ml
1.50
28
37
853
816
11.38
307.65
1.2
1.1
0.94
1.80
iu/ml
0.75
11
12
2870
1199
13.81
307.65
1.1
1.1
1.56
2.29
iu/ml
0.91
45
42
983
556
20.80
307.65
1.1
1.1
1.60
2.55
iu/ml
—
8
6
1050
568
19.83
307.65
1.1
1.1
1.54
2.21
iu/ml
0.42
15
14
1726
1588
7.51
307.65
1.1
1.1
1.35
2.45
iu/ml
1.81
31
41
1087
925
12.90
307.65
1.2
1.1
1.83
1.69
iu/ml
—
8
11
1213
1266
10.29
307.65
1.2
1.1
1.80
1.85
iu/ml
0.03
13
23
1006
504
10.21
307.65
1.1
1.1
2.22
2.95
iu/ml
—
7
15
2481
1096
13.21
307.65
1.2
1.1
1.76
2.31
iu/ml
0.57
33
45
3067
1123
15.58
307.65
1.2
1.1
1.61
2.31
iu/ml
0.95
42
45
2967
1602
10.91
307.65
1.1
1.1
1.60
2.20
iu/ml
0.82
41
54
2966
892
34.76
307.65
1.1
1.1
1.41
2.51
iu/ml
1.49
36
34
2734
2003
12.64
307.65
1.2
1.1
1.69
2.10
iu/ml
0.46
33
62
2118
1129
9.76
307.65
1.1
1.1
2.07
2.33
iu/ml
0.20
30
41
484
647
7.88
307.65
1.1
1.1
0.72
2.07
iu/ml
—
6
9
784
848
9.81
307.65
1.1
1.1
1.46
1.97
iu/ml
0.36
18
17
2504
1523
10.29
307.65
1.2
1.1
1.57
2.17
iu/ml
0.74
33
52
1087
897
13.30
307.65
1.2
1.1
1.83
1.53
iu/ml
—
8
10
477
391
12.84
307.65
1.1
1.1
2.05
1.27
iu/ml
—
5
5
1111
610
21.48
307.65
1.1
1.1
1.50
2.93
iu/ml
—
9
5
605
801
7.82
307.65
1.1
1.1
1.56
2.09
iu/ml
—
10
21
1948
1747
11.82
307.65
1.1
1.1
1.60
2.41
iu/ml
0.93
33
38
781
837
9.91
307.65
1.1
1.1
1.46
1.97
iu/ml
0.36
18
17
2562
1511
9.54
307.65
1.2
1.1
1.69
2.09
iu/ml
0.45
33
54
1088
1225
9.38
307.65
1.1
1.1
1.35
2.23
iu/ml
1.10
21
30
2830
1168
14.04
307.65
1.1
1.1
1.58
2.29
iu/ml
0.88
44
42
553
761
7.54
307.65
1.1
1.1
1.56
2.50
iu/ml
—
10
21
1748
1973
5.16
307.65
1.1
1.1
1.38
2.24
iu/ml
1.45
21
48
1019
777
12.63
307.65
1.1
1.1
1.39
2.38
iu/ml
1.24
20
25
823
932
9.41
307.65
1.2
1.1
1.23
1.75
iu/ml
—
5
15
595
1147
5.38
292.04
1.1
1.1
1.57
2.14
iu/ml
—
9
23
669
1564
4.40
259.39
1.1
1.1
1.57
2.01
iu/ml
—
9
36
323
389
8.85
250.30
1.1
1.1
0.98
2.89
iu/ml
—
5
5
320
397
8.63
242.30
1.1
1.1
0.92
2.89
iu/ml
—
6
5
583
1309
4.58
238.08
1.2
1.1
2.03
1.79
iu/ml
0.12
12
33
1186
2025
3.02
216.75
1.1
1.1
1.18
2.49
iu/ml
2.91
17
45
362
575
6.41
215.17
1.2
1.1
2.00
2.11
iu/ml
—
9
20
382
705
5.63
197.08
1.1
1.1
1.25
2.22
iu/ml
—
7
16
169
124
15.08
185.02
1.2
1.1
—
—
—
0
0
570
932
4.09
178.13
1.1
1.1
1.91
2.42
iu/ml
—
10
38
829
1936
2.91
156.03
1.2
1.1
1.03
2.53
iu/ml
2.96
11
43
718
2254
3.00
155.07
1.2
1.1
2.41
1.65
iu/ml
0.80
34
50
367
812
4.63
152.57
1.2
1.1
1.70
1.84
iu/ml
—
7
8
970
1864
2.64
140.00
1.2
1.1
1.27
2.17
iu/ml
—
9
32
970
1864
2.64
140.00
1.2
1.1
1.27
2.17
iu/ml
—
9
32
525
1552
3.35
138.30
1.2
1.1
2.47
1.60
iu/ml
0.93
33
42
667
2146
2.92
138.03
1.2
1.1
1.55
1.81
iu/ml
0.15
12
47
1139
2457
2.35
129.85
1.1
1.1
2.29
1.74
iu/ml
0.40
14
56
1302
3209
2.12
119.01
1.1
1.1
1.77
2.13
iu/ml
0.35
30
63
341
862
4.01
118.18
1.3
1.1
1.94
1.88
iu/ml
—
7
34
367
1017
3.69
112.53
1.2
1.1
2.00
1.69
iu/ml
—
9
21
876
2251
2.39
109.87
1.1
1.1
1.34
2.17
iu/ml
1.13
15
55
892
2019
2.37
106.48
1.2
1.1
0.88
2.49
iu/ml
4.24
13
45
679
1761
2.58
102.48
1.2
1.1
1.84
2.37
iu/ml
—
9
40
67
24
36.15
102.24
1.2
1.2
—
—
—
0
0
658
2665
2.50
102.21
1.1
1.1
1.99
2.13
iu/ml
0.08
13
61
111
109
11.05
100.80
1.1
1.1
—
—
—
0
0
679
1300
2.64
98.61
1.1
1.1
2.49
1.89
iu/ml
—
5
29
326
933
3.58
95.41
1.2
1.1
3.48
2.20
iu/ml
—
6
18
557
2170
2.60
94.03
1.1
1.1
1.99
2.03
iu/ml
0.02
13
50
1019
2694
2.10
91.84
1.2
1.1
1.93
2.13
iu/ml
0.14
18
57
1123
3753
1.98
90.50
1.1
1.1
2.24
1.87
iu/ml
0.28
20
83
423
1318
2.97
90.37
1.2
1.1
2.13
1.77
iu/ml
0.18
11
50
296
849
3.57
86.44
1.2
1.1
4.03
1.80
iu/ml
—
5
13
1156
2962
1.97
86.28
1.2
1.1
1.41
1.87
iu/ml
0.53
17
57
280
781
3.67
85.31
1.2
1.1
4.03
1.80
iu/ml
—
5
13
1048
2768
2.00
82.93
1.1
1.1
1.56
2.13
iu/ml
0.59
20
57
1105
3328
1.94
82.64
1.2
1.1
3.31
1.51
iu/ml
1.92
18
68
866
2080
2.14
80.89
1.1
1.1
1.71
2.37
iu/ml
0.53
16
39
74
57
14.07
78.49
1.3
1.1
—
—
—
0
0
493
1777
2.53
77.29
1.2
1.1
1.75
1.99
iu/ml
0.11
12
53
351
566
3.34
77.04
1.1
1.2
1.88
1.99
iu/ml
—
7
13
1153
3433
1.87
76.42
1.2
1.1
1.79
1.96
iu/ml
0.15
23
77
577
2551
2.29
73.78
1.2
1.1
2.27
1.97
iu/ml
0.14
13
51
710
1682
2.18
69.39
1.1
1.1
2.36
1.95
iu/ml
0.20
13
30
450
1816
2.44
66.25
1.1
1.1
1.60
1.95
iu/ml
0.25
16
53
729
2287
2.06
66.12
1.2
1.1
1.05
2.12
iu/ml
2.32
15
52
173
412
4.32
65.99
1.3
1.1
0.58
2.37
iu/ml
—
5
5
399
1557
2.57
65.86
1.1
1.1
1.63
2.17
iu/ml
0.35
14
42
60
46
15.20
64.50
1.3
1.1
—
—
—
0
0
173
427
4.16
62.91
1.3
1.1
0.58
2.02
iu/ml
—
5
7
975
2650
1.85
61.28
1.1
1.1
2.13
1.85
iu/ml
0.20
22
43
194
531
3.73
60.85
1.1
1.1
1.78
2.76
iu/ml
—
9
19
388
1483
2.51
60.52
1.2
1.1
2.04
2.11
iu/ml
0.04
14
53
172
436
4.03
60.26
1.1
1.1
1.78
2.26
iu/ml
—
9
12
172
438
4.01
59.87
1.1
1.1
1.78
2.26
iu/ml
—
9
12
172
439
4.01
59.68
1.1
1.1
1.78
2.26
iu/ml
—
9
12
172
439
4.01
59.68
1.1
1.1
1.78
2.26
iu/ml
—
9
12
321
1199
2.71
59.25
1.2
1.1
1.68
1.84
iu/ml
0.08
13
29
841
2807
1.89
59.24
1.2
1.1
2.47
2.06
iu/ml
0.28
20
57
841
2807
1.89
59.24
1.2
1.1
2.47
2.06
iu/ml
0.28
20
57
843
3134
1.87
58.95
1.2
1.1
2.23
1.89
iu/ml
0.21
18
68
488
1236
2.34
58.66
1.1
1.1
1.10
2.11
iu/ml
1.71
15
37
233
734
3.23
58.65
1.2
1.1
2.22
1.59
iu/ml
—
7
15
880
2956
1.85
57.99
1.1
1.1
1.62
2.23
iu/ml
0.38
12
58
842
3305
1.86
57.76
1.2
1.1
2.58
1.80
iu/ml
0.66
22
64
68
76
9.90
56.45
1.2
1.1
—
—
—
0
0
52
41
14.73
54.95
1.2
1.1
—
—
—
0
0
350
1361
2.51
54.88
1.2
1.1
2.14
2.14
iu/ml
0.00
13
51
346
1351
2.50
54.13
1.2
1.1
2.14
2.14
iu/ml
0.00
13
51
764
3161
1.87
54.04
1.2
1.1
1.92
1.95
iu/ml
0.02
18
69
311
1203
2.60
53.19
1.2
1.1
1.57
2.47
iu/ml
—
9
31
884
2456
1.82
52.95
1.1
1.1
1.36
2.09
iu/ml
1.05
15
52
981
2807
1.76
52.31
1.1
1.1
1.78
2.06
iu/ml
0.17
15
57
981
2807
1.76
52.31
1.1
1.1
1.78
2.06
iu/ml
0.17
15
57
759
2008
1.91
51.92
1.1
1.1
2.42
2.52
iu/ml
0.05
14
29
377
1631
2.33
50.85
1.2
1.1
2.85
2.40
iu/ml
—
6
28
754
2008
1.89
50.60
1.1
1.1
2.04
2.52
iu/ml
0.27
13
29
226
724
3.02
50.40
1.1
1.1
1.05
2.26
iu/ml
—
5
18
999
2980
1.72
49.55
1.1
1.1
1.12
2.11
iu/ml
2.18
16
63
835
2325
1.81
48.84
1.1
1.1
1.17
1.93
iu/ml
—
10
30
363
1384
2.35
48.49
1.1
1.1
2.46
1.70
iu/ml
0.62
18
48
598
2762
1.93
48.36
1.1
1.1
1.44
2.05
iu/ml
0.53
17
53
863
3897
1.73
48.12
1.1
1.1
0.98
2.14
iu/ml
3.52
17
86
441
1435
2.19
47.95
1.1
1.1
1.72
2.19
iu/ml
0.34
19
41
907
3679
1.72
47.88
1.2
1.1
2.29
1.83
iu/ml
0.36
22
69
744
2010
1.87
47.84
1.1
1.1
2.36
2.56
iu/ml
0.09
15
28
744
2010
1.87
47.84
1.1
1.1
2.36
2.56
iu/ml
0.09
15
28
166
482
3.51
47.78
1.1
1.1
1.61
2.37
iu/ml
—
6
7
143
385
3.79
46.12
1.1
1.1
1.67
2.62
iu/ml
—
8
10
79
133
6.23
45.33
1.1
1.1
—
—
—
0
0
952
3778
1.67
44.48
1.2
1.1
2.30
1.81
iu/ml
0.40
22
70
749
3272
1.76
44.27
1.1
1.1
2.20
1.85
iu/ml
0.23
19
77
399
1879
2.14
43.90
1.2
1.1
1.67
1.89
iu/ml
—
8
40
899
3717
1.68
43.64
1.2
1.1
2.37
1.82
iu/ml
0.44
21
70
330
1447
2.30
43.33
1.2
1.1
1.72
1.97
iu/ml
0.14
11
26
324
1419
2.31
42.72
1.2
1.1
2.11
1.78
iu/ml
—
9
27
376
1662
2.17
42.51
1.1
1.1
4.54
1.22
iu/ml
—
9
44
922
2772
1.68
41.50
1.1
1.1
1.22
2.20
iu/ml
1.97
15
58
505
1389
2.01
41.42
1.1
1.1
1.29
2.57
iu/ml
2.16
12
37
929
3445
1.65
40.94
1.1
1.1
1.70
2.05
iu/ml
0.36
30
60
468
2269
1.97
40.76
1.2
1.1
0.93
2.20
iu/ml
—
8
49
915
2772
1.67
40.57
1.1
1.1
1.29
2.20
iu/ml
1.88
17
58
844
2990
1.69
40.52
1.1
1.1
2.23
1.74
iu/ml
0.38
17
55
145
430
3.43
40.42
1.2
1.1
2.73
2.01
iu/ml
—
9
16
1007
3300
1.62
40.31
1.1
1.1
1.56
2.08
iu/ml
0.48
19
79
431
1689
2.04
39.85
1.2
1.1
1.14
2.60
iu/ml
1.65
11
24
424
1638
2.05
39.65
1.2
1.1
1.14
2.60
iu/ml
1.65
11
24
641
2794
1.78
39.06
1.1
1.1
1.47
2.22
iu/ml
0.84
11
58
577
2177
1.84
38.44
1.2
1.1
1.80
1.98
iu/ml
0.10
14
59
575
2658
1.82
38.42
1.2
1.1
3.30
2.04
iu/ml
0.79
14
49
366
1761
2.10
38.18
1.2
1.1
1.97
2.06
iu/ml
—
10
35
361
1732
2.11
37.96
1.2
1.1
3.26
1.80
iu/ml
—
6
21
644
1918
1.80
37.81
1.1
1.1
1.66
2.56
iu/ml
0.74
15
28
424
1188
2.06
37.57
1.1
1.1
1.15
2.26
iu/ml
1.87
14
33
38
33
12.73
37.52
1.3
1.2
—
—
—
0
0
768
3120
1.68
37.32
1.1
1.1
1.35
1.99
iu/ml
0.75
17
68
814
3225
1.65
36.44
1.1
1.1
1.35
2.16
iu/ml
1.01
17
73
628
3309
1.74
36.24
1.2
1.1
1.13
2.22
iu/ml
2.40
13
68
938
3051
1.60
36.14
1.1
1.1
1.62
2.17
iu/ml
0.45
16
61
650
1982
1.77
36.13
1.1
1.1
1.66
2.56
iu/ml
0.74
15
28
480
2589
1.87
35.88
1.1
1.1
1.67
2.25
iu/ml
—
8
60
247
1034
2.40
35.70
1.2
1.1
2.08
2.08
iu/ml
—
9
32
303
1397
2.19
35.37
1.2
1.1
0.79
1.90
iu/ml
—
6
34
646
1844
1.76
35.05
1.1
1.1
1.44
2.25
iu/ml
—
9
43
873
2942
1.61
34.87
1.1
1.1
1.34
2.14
iu/ml
1.15
14
62
916
3855
1.57
33.48
1.1
1.1
1.74
1.96
iu/ml
0.13
15
88
889
2963
1.59
33.20
1.1
1.1
1.81
2.14
iu/ml
0.22
15
62
401
2079
1.93
33.15
1.2
1.1
1.83
1.96
iu/ml
0.08
39
11
39
42
10.04
33.14
1.3
1.2
—
—
—
0
0
70
141
5.13
33.07
1.2
1.0
—
—
—
0
0
891
3563
1.57
33.05
1.1
1.1
1.80
2.01
iu/ml
0.12
14
85
512
2881
1.78
32.92
1.2
1.1
1.62
2.08
iu/ml
0.37
18
55
298
1361
2.12
31.99
1.2
1.1
1.84
1.87
iu/ml
—
9
45
705
2177
1.67
31.72
1.1
1.1
3.16
1.71
iu/ml
—
9
62
526
2782
1.74
30.99
1.1
1.1
2.12
1.95
iu/ml
0.08
14
67
622
2010
1.71
30.95
1.1
1.1
1.81
2.56
iu/ml
0.53
13
28
569
1982
1.74
30.93
1.1
1.1
1.26
2.56
iu/ml
1.72
14
28
740
2335
1.63
30.68
1.1
1.1
2.88
1.70
iu/ml
—
10
63
663
3180
1.64
30.68
1.2
1.1
2.39
1.77
iu/ml
0.52
21
69
760
2415
1.62
30.63
1.1
1.1
2.95
1.80
iu/ml
0.91
14
50
559
1918
1.74
30.57
1.1
1.1
1.31
2.56
iu/ml
1.60
13
28
437
2411
1.83
30.51
1.1
1.1
2.39
1.87
iu/ml
—
5
41
35
37
10.48
30.27
1.1
1.0
—
—
—
0
0
656
3006
1.64
30.12
1.2
1.1
2.56
1.91
iu/ml
—
8
62
827
3489
1.56
29.93
1.1
1.1
1.41
2.12
iu/ml
0.93
19
75
628
2765
1.65
29.18
1.1
1.1
2.22
2.18
iu/ml
—
9
57
248
1101
2.20
29.14
1.1
1.1
2.02
2.19
iu/ml
0.09
12
40
260
1133
2.15
28.84
1.1
1.1
2.66
2.17
iu/ml
0.29
13
39
263
1226
2.12
28.41
1.2
1.1
2.16
1.78
iu/ml
—
7
38
268
906
2.15
28.31
1.1
1.1
0.81
2.10
iu/ml
—
7
33
351
1243
1.94
27.85
1.1
1.1
1.82
2.33
iu/ml
—
8
35
913
3025
1.52
27.76
1.1
1.1
1.69
1.74
iu/ml
0.03
15
55
318
1570
1.96
27.39
1.2
1.1
1.75
1.92
iu/ml
—
10
48
568
1682
1.70
27.36
1.1
1.1
1.65
1.95
iu/ml
0.19
12
30
508
1711
1.74
27.19
1.1
1.1
—
2.33
—
0
28
590
2632
1.64
26.84
1.2
1.1
2.40
1.74
iu/ml
0.57
24
61
482
1766
1.73
26.04
1.2
1.1
1.88
1.86
iu/ml
0.01
17
31
157
627
2.53
25.67
1.2
1.1
1.16
2.08
iu/ml
—
6
23
534
2517
1.66
25.63
1.2
1.1
2.18
1.90
iu/ml
0.18
15
63
516
2309
1.68
25.58
1.2
1.1
0.93
2.03
iu/ml
—
7
40
304
1109
1.97
25.47
1.1
1.1
0.70
2.36
iu/ml
—
6
31
255
1254
2.05
25.33
1.2
1.1
1.64
2.42
iu/ml
—
6
27
839
3527
1.50
25.29
1.1
1.1
2.03
1.91
iu/ml
0.07
17
81
330
1769
1.88
25.15
1.2
1.1
1.92
2.98
iu/ml
—
31
6
399
2275
1.77
25.11
1.2
1.1
1.10
2.10
iu/ml
—
6
37
199
889
2.25
24.97
1.2
1.1
3.66
1.53
iu/ml
—
5
16
215
979
2.18
24.92
1.2
1.1
1.95
2.09
iu/ml
—
7
24
769
3657
1.51
24.82
1.2
1.1
1.34
2.13
iu/ml
1.17
22
77
674
2436
1.57
24.65
1.1
1.1
1.17
2.06
iu/ml
—
6
46
673
2433
1.57
24.56
1.1
1.1
1.17
2.06
iu/ml
—
6
46
32
39
8.57
24.56
1.4
1.2
—
—
—
0
0
306
1437
1.91
24.24
1.2
1.1
0.86
2.04
iu/ml
2.14
11
48
32
10
16.43
24.00
1.3
1.1
—
—
—
0
0
174
753
2.33
23.87
1.2
1.1
2.48
1.56
iu/ml
—
6
16
217
1021
2.12
23.62
1.2
1.1
3.15
1.53
iu/ml
—
6
16
127
482
2.67
23.13
1.2
1.1
1.94
1.68
iu/ml
—
6
9
195
700
2.23
22.97
1.1
1.1
1.85
2.42
iu/ml
0.27
13
14
260
1217
1.97
22.90
1.2
1.1
0.86
2.08
iu/ml
2.09
11
44
338
1766
1.80
22.64
1.2
1.1
0.98
2.09
iu/ml
—
7
55
997
3542
1.43
22.56
1.1
1.1
1.66
2.20
iu/ml
0.59
21
71
430
2067
1.68
21.95
1.2
1.1
2.27
1.80
iu/ml
0.33
22
56
153
657
2.35
21.37
1.1
1.1
2.14
2.62
iu/ml
—
10
18
556
2757
1.57
21.26
1.2
1.1
2.47
1.89
iu/ml
0.36
13
63
522
3315
1.57
21.24
1.1
1.1
2.55
1.96
iu/ml
0.53
17
65
276
1212
1.89
21.08
1.1
1.1
2.34
1.79
iu/ml
0.33
15
45
632
2356
1.54
21.05
1.1
1.1
1.17
2.09
iu/ml
—
6
45
934
3366
1.43
21.04
1.2
1.1
1.81
1.99
iu/ml
0.13
16
71
169
670
2.25
20.96
1.1
1.1
2.12
2.16
iu/ml
0.02
13
28
408
2209
1.67
20.90
1.1
1.1
1.13
2.25
iu/ml
—
10
49
42
82
5.25
20.59
1.2
1.1
—
—
—
0
0
285
1194
1.86
20.50
1.1
1.1
2.70
1.93
iu/ml
0.45
13
25
813
3930
1.44
20.43
1.1
1.1
1.32
2.07
iu/ml
1.04
13
87
368
1857
1.71
20.28
1.1
1.1
0.76
2.07
iu/ml
—
9
46
525
1651
1.60
20.21
1.1
1.1
2.18
2.40
iu/ml
—
6
27
107
400
2.71
20.14
1.1
1.1
0.91
2.13
iu/ml
—
5
8
314
1708
1.77
20.13
1.1
1.1
1.91
1.58
iu/ml
—
6
37
331
1912
1.74
19.98
1.1
1.1
1.15
2.05
iu/ml
—
5
33
694
2405
1.50
19.95
1.1
1.1
1.68
1.81
iu/ml
0.10
14
49
320
1304
1.78
19.75
1.1
1.1
1.10
2.10
iu/ml
—
7
50
635
3315
1.50
19.71
1.2
1.1
1.70
2.04
iu/ml
0.28
18
68
181
867
2.11
19.46
1.2
1.1
—
2.21
—
0
18
875
3209
1.42
19.42
1.1
1.1
1.50
1.93
iu/ml
0.33
17
66
875
3210
1.42
19.37
1.1
1.1
1.50
1.93
iu/ml
0.33
17
66
530
3290
1.54
19.27
1.2
1.1
1.02
2.19
iu/ml
3.07
14
77
23
25
9.59
19.23
1.3
1.1
3.21
—
iu/ml
—
8
0
872
3205
1.42
19.12
1.1
1.1
1.44
1.96
iu/ml
0.44
18
65
253
906
1.90
19.10
1.1
1.1
0.81
2.34
iu/ml
—
7
30
259
1419
1.84
18.82
1.2
1.1
2.32
1.80
iu/ml
—
5
13
580
1942
1.53
18.71
1.1
1.1
3.14
1.58
iu/ml
—
10
54
580
1944
1.53
18.61
1.1
1.1
2.93
1.58
iu/ml
0.89
11
54
398
1496
1.66
18.52
1.1
1.1
1.92
1.83
iu/ml
0.04
14
30
622
2119
1.51
18.52
1.1
1.1
3.09
1.57
iu/ml
1.15
12
55
666
3363
1.46
18.51
1.2
1.1
1.91
1.92
iu/ml
0.00
23
66
208
1067
1.96
18.49
1.2
1.1
1.03
2.36
iu/ml
—
7
21
662
3362
1.46
18.31
1.1
1.1
1.91
1.92
iu/ml
0.00
23
66
340
2031
1.68
18.20
1.1
1.1
1.08
2.31
iu/ml
—
6
38
508
3266
1.53
18.09
1.2
1.1
0.99
2.25
iu/ml
—
8
63
112
343
2.56
18.06
1.1
1.1
2.22
2.52
iu/ml
—
12
8
635
2188
1.49
17.96
1.1
1.1
2.12
1.74
iu/ml
0.33
11
59
662
3362
1.46
17.96
1.1
1.1
1.91
1.92
iu/ml
0.00
23
66
434
2487
1.58
17.92
1.1
1.1
0.55
2.06
iu/ml
—
5
55
211
1106
1.92
17.65
1.2
1.1
1.77
2.17
iu/ml
—
5
21
122
488
2.38
17.60
1.1
1.1
2.12
2.38
iu/ml
—
9
19
216
1145
1.90
17.47
1.1
1.1
1.50
2.39
iu/ml
—
9
20
448
1902
1.57
17.07
1.2
1.1
1.95
1.34
iu/ml
0.49
14
51
423
2395
1.57
17.03
1.2
1.1
1.39
1.92
iu/ml
0.54
11
62
459
2547
1.54
16.93
1.2
1.1
2.36
1.90
iu/ml
—
10
38
963
3836
1.36
16.85
1.1
1.1
1.96
2.03
iu/ml
0.05
25
72
584
2205
1.49
16.79
1.1
1.1
1.71
2.25
iu/ml
—
9
59
137
625
2.21
16.76
1.2
1.1
2.37
2.30
iu/ml
—
5
21
179
905
1.99
16.64
1.1
1.1
2.86
1.93
iu/ml
—
9
21
585
2017
1.49
16.55
1.1
1.1
2.17
1.74
iu/ml
—
10
59
362
2254
1.61
16.54
1.2
1.1
2.11
2.00
iu/ml
0.05
12
47
329
1971
1.65
16.41
1.2
1.1
0.94
1.84
iu/ml
—
6
42
25
37
7.16
16.33
1.1
1.1
—
—
—
0
0
148
704
2.12
16.28
1.2
1.1
1.00
2.44
iu/ml
—
5
24
448
1472
1.57
16.09
1.1
1.1
3.30
1.83
iu/ml
—
6
48
502
1694
1.52
15.86
1.1
1.1
2.42
1.57
iu/ml
—
9
44
604
3007
1.44
15.64
1.1
1.1
2.80
1.57
iu/ml
0.95
18
72
149
723
2.08
15.59
1.2
1.1
2.37
2.30
iu/ml
—
5
21
350
2003
1.60
15.32
1.1
1.1
1.29
2.00
iu/ml
0.80
11
57
471
3134
1.50
15.30
1.2
1.1
1.10
2.20
iu/ml
—
6
62
304
1530
1.66
15.28
1.1
1.1
3.11
1.75
iu/ml
—
6
42
333
1476
1.63
15.12
1.1
1.1
1.03
2.21
iu/ml
—
8
60
472
3149
1.49
15.08
1.2
1.1
1.10
2.20
iu/ml
—
6
62
33
69
4.94
15.07
1.2
1.1
—
—
—
0
0
145
373
2.17
14.94
1.1
1.1
1.69
1.94
iu/ml
—
6
11
576
3483
1.43
14.85
1.1
1.1
1.42
2.15
iu/ml
0.84
18
74
404
1723
1.56
14.84
1.2
1.1
1.10
2.04
iu/ml
—
5
25
339
1158
1.64
14.83
1.1
1.1
1.64
1.81
iu/ml
—
5
12
24
673
0.22
14.80
1.1
1.1
—
3.19
—
0
6
96
399
2.43
14.67
1.1
1.1
—
2.90
—
0
7
326
1455
1.62
14.49
1.1
1.1
1.03
2.21
iu/ml
—
8
60
17
18
9.96
14.46
1.4
1.1
—
—
—
0
0
274
1455
1.68
14.36
1.2
1.1
2.09
1.86
iu/ml
—
6
44
214
1115
1.79
14.28
1.2
1.1
2.20
1.74
iu/ml
—
8
35
716
2629
1.39
14.15
1.1
1.1
1.65
2.15
iu/ml
—
8
52
678
3230
1.39
14.06
1.1
1.1
1.90
2.08
iu/ml
0.13
12
75
187
826
1.87
14.05
1.1
1.1
0.66
2.52
iu/ml
—
5
33
15
14
11.94
14.00
1.1
1.0
—
—
—
0
0
846
3281
1.35
13.92
1.1
1.1
1.62
2.13
iu/ml
0.45
24
72
425
2806
1.50
13.91
1.1
1.1
1.03
2.03
iu/ml
—
7
61
425
2806
1.50
13.91
1.1
1.1
1.03
2.03
iu/ml
—
7
61
659
3133
1.39
13.86
1.1
1.1
1.98
2.08
iu/ml
0.07
11
72
25
44
5.94
13.81
1.2
1.2
—
—
—
0
0
129
621
2.09
13.80
1.1
1.1
1.24
1.94
iu/ml
—
6
10
628
3785
1.39
13.77
1.1
1.1
2.39
2.08
iu/ml
0.14
13
68
29
59
5.07
13.67
1.3
1.1
—
—
—
0
0
858
3351
1.34
13.60
1.1
1.1
1.55
1.96
iu/ml
0.26
14
73
384
2418
1.52
13.60
1.1
1.1
0.72
1.89
iu/ml
—
5
54
745
3336
1.36
13.55
1.2
1.1
2.10
2.16
iu/ml
0.03
13
74
728
4168
1.36
13.54
1.2
1.1
1.24
2.07
iu/ml
1.04
14
88
816
3165
1.35
13.49
1.1
1.1
1.12
2.20
iu/ml
2.52
12
77
591
2566
1.41
13.42
1.1
1.1
1.58
2.11
iu/ml
0.38
13
57
523
2222
1.45
13.40
1.1
1.1
1.30
2.17
iu/ml
1.48
12
53
856
3359
1.33
13.18
1.1
1.1
1.55
1.96
iu/ml
0.26
14
73
501
1761
1.46
13.07
1.1
1.1
3.27
1.64
iu/ml
—
9
48
794
3910
1.34
12.98
1.2
1.1
2.00
2.06
iu/ml
0.03
14
77
17
21
8.64
12.92
1.1
1.0
—
—
—
0
0
792
3911
1.34
12.84
1.2
1.1
2.00
2.06
iu/ml
0.03
14
77
577
3006
1.40
12.70
1.2
1.1
1.91
1.88
iu/ml
0.02
16
65
613
3028
1.39
12.60
1.1
1.1
1.78
2.07
iu/ml
0.20
11
67
697
3365
1.36
12.58
1.1
1.1
2.33
1.97
iu/ml
—
10
80
23
41
5.86
12.54
1.3
1.2
—
—
—
0
0
745
3836
1.34
12.51
1.2
1.1
2.26
2.14
iu/ml
0.05
11
73
473
1661
1.46
12.49
1.1
1.1
2.12
1.87
iu/ml
—
7
53
506
1766
1.44
12.30
1.1
1.1
1.45
2.43
iu/ml
—
6
29
253
1561
1.63
12.18
1.2
1.1
2.08
2.18
iu/ml
—
8
30
23
42
5.62
12.18
1.3
1.2
1.74
—
iu/ml
—
7
0
540
3545
1.39
11.99
1.2
1.1
0.90
2.20
iu/ml
—
10
62
163
896
1.83
11.96
1.2
1.1
2.32
2.39
iu/ml
—
5
9
324
2126
1.53
11.95
1.2
1.1
2.25
2.04
iu/ml
0.09
11
46
23
43
5.48
11.88
1.3
1.2
1.74
—
iu/ml
—
7
0
244
1242
1.64
11.77
1.1
1.1
1.89
1.70
iu/ml
0.13
18
42
704
3264
1.34
11.71
1.2
1.1
1.80
2.06
iu/ml
0.16
12
58
95
436
2.20
11.64
1.1
1.1
—
2.89
—
0
5
29
68
4.39
11.56
1.3
1.1
—
—
—
0
0
253
1296
1.62
11.52
1.1
1.1
1.89
1.80
iu/ml
0.05
18
43
630
4002
1.35
11.48
1.1
1.1
1.18
2.07
iu/ml
2.15
15
86
288
1342
1.57
11.45
1.2
1.1
1.76
2.15
iu/ml
—
9
40
552
3777
1.38
11.43
1.1
1.1
1.48
1.98
iu/ml
—
7
73
274
946
1.61
11.36
1.1
1.1
1.64
1.65
iu/ml
—
5
10
685
2555
1.35
11.23
1.1
1.1
1.78
1.99
iu/ml
0.12
11
51
20
35
5.97
11.12
1.3
1.2
—
—
—
0
0
449
2385
1.42
11.09
1.1
1.1
2.75
1.77
iu/ml
—
6
35
885
3995
1.29
11.04
1.1
1.1
1.87
1.96
iu/ml
0.06
19
84
287
1351
1.56
10.99
1.2
1.1
1.76
2.15
iu/ml
—
9
40
593
3487
1.36
10.99
1.1
1.1
1.56
1.94
iu/ml
0.34
11
60
675
3274
1.33
10.81
1.2
1.1
1.40
1.95
iu/ml
0.82
11
79
25
55
4.69
10.79
1.3
1.1
—
—
—
0
0
561
3607
1.36
10.76
1.1
1.1
2.73
2.04
iu/ml
0.31
11
58
303
1982
1.51
10.64
1.1
1.1
1.72
2.13
iu/ml
—
5
27
172
997
1.73
10.54
1.1
1.1
3.68
1.26
iu/ml
—
8
30
589
3461
1.35
10.48
1.1
1.1
1.96
1.90
iu/ml
0.04
11
59
346
2044
1.47
10.38
1.1
1.1
1.70
2.03
iu/ml
—
7
44
637
3181
1.33
10.25
1.2
1.1
2.04
2.24
iu/ml
—
8
69
14
18
8.18
10.24
1.2
1.1
—
—
—
0
0
610
2790
1.34
10.12
1.2
1.1
2.42
1.72
iu/ml
—
10
52
681
3702
1.31
9.97
1.2
1.1
2.04
2.05
iu/ml
—
8
71
329
2255
1.47
9.90
1.2
1.1
1.75
2.17
iu/ml
—
9
39
142
792
1.80
9.90
1.1
1.1
2.46
2.08
iu/ml
—
6
23
685
3719
1.31
9.90
1.2
1.1
2.04
2.03
iu/ml
—
8
72
423
2398
1.41
9.89
1.1
1.1
0.98
2.24
iu/ml
—
8
51
594
3515
1.33
9.85
1.1
1.1
1.85
1.95
iu/ml
0.07
12
61
227
1431
1.58
9.72
1.1
1.1
2.67
1.64
iu/ml
—
6
34
246
1343
1.56
9.67
1.1
1.1
1.82
1.83
iu/ml
0.00
19
45
322
2145
1.46
9.60
1.2
1.1
2.52
2.04
iu/ml
—
6
65
742
3230
1.30
9.59
1.2
1.1
2.53
1.90
iu/ml
0.45
18
69
327
2254
1.46
9.58
1.2
1.1
1.75
2.17
iu/ml
—
9
39
18
33
5.68
9.54
1.1
1.1
—
—
—
0
0
526
2843
1.35
9.46
1.1
1.1
2.54
1.78
iu/ml
0.46
15
70
166
677
1.72
9.43
1.2
1.1
1.12
2.25
iu/ml
—
6
17
229
1473
1.56
9.38
1.1
1.1
2.75
2.12
iu/ml
—
6
38
399
2123
1.41
9.37
1.1
1.1
1.41
2.00
iu/ml
—
10
45
224
1440
1.56
9.22
1.1
1.1
1.05
2.27
iu/ml
—
8
31
245
1349
1.54
9.19
1.1
1.1
1.89
1.83
iu/ml
0.04
18
45
243
1360
1.54
9.09
1.2
1.1
2.77
1.85
iu/ml
0.53
12
44
296
2024
1.47
9.08
1.1
1.1
1.84
2.02
iu/ml
—
7
38
11
12
9.65
9.06
1.1
1.3
—
—
—
0
0
293
1655
1.48
9.05
1.1
1.1
1.97
1.75
iu/ml
0.16
20
52
84
412
2.06
8.78
1.2
1.1
—
2.47
—
0
6
662
2555
1.30
8.69
1.1
1.1
1.68
1.99
iu/ml
0.20
12
51
475
2643
1.35
8.68
1.2
1.1
2.46
1.89
iu/ml
0.25
11
60
448
1638
1.37
8.53
1.1
1.1
2.27
1.69
iu/ml
—
6
29
288
1942
1.46
8.52
1.1
1.1
2.27
1.97
iu/ml
—
10
61
782
3852
1.26
8.32
1.2
1.1
2.00
2.03
iu/ml
0.02
18
72
65
295
2.22
8.31
1.2
1.1
1.12
2.64
iu/ml
—
5
5
377
2028
1.39
8.30
1.1
1.1
0.84
2.16
iu/ml
3.48
11
65
142
820
1.70
8.27
1.2
1.1
1.40
2.23
iu/ml
—
7
35
142
820
1.70
8.27
1.2
1.1
1.40
2.23
iu/ml
—
7
35
598
2921
1.30
8.15
1.1
1.1
1.66
2.22
iu/ml
—
10
52
539
2042
1.33
8.15
1.1
1.1
2.25
2.00
iu/ml
—
6
39
346
2240
1.40
8.09
1.1
1.1
1.99
1.92
iu/ml
0.03
14
64
141
819
1.69
8.05
1.2
1.1
1.40
2.23
iu/ml
—
7
35
141
819
1.69
8.05
1.2
1.1
1.40
2.23
iu/ml
—
7
35
233
1557
1.50
7.95
1.2
1.1
2.52
2.15
iu/ml
—
6
48
575
2951
1.30
7.94
1.1
1.1
1.17
2.02
iu/ml
1.48
13
69
141
823
1.68
7.89
1.2
1.1
1.40
2.23
iu/ml
—
7
35
297
1849
1.43
7.86
1.1
1.1
—
1.61
—
0
21
81
402
1.99
7.79
1.1
1.1
2.14
1.96
iu/ml
—
9
16
365
1967
1.38
7.77
1.1
1.1
1.08
1.94
iu/ml
—
8
47
17
36
4.93
7.73
1.1
1.1
—
—
—
0
0
582
4065
1.29
7.71
1.1
1.1
1.25
2.11
iu/ml
1.89
14
83
193
1256
1.54
7.61
1.1
1.1
0.96
2.14
iu/ml
—
7
20
11
15
7.63
7.61
1.0
1.0
—
—
—
0
0
593
3081
1.29
7.56
1.1
1.1
1.80
2.01
iu/ml
0.17
18
64
504
2316
1.32
7.54
1.2
1.1
0.76
2.14
iu/ml
—
6
34
133
793
1.69
7.53
1.1
1.1
2.73
1.92
iu/ml
—
6
16
747
3335
1.25
7.50
1.1
1.1
1.66
2.07
iu/ml
0.45
18
57
165
882
1.60
7.49
1.1
1.1
2.19
2.11
iu/ml
0.03
13
32
241
1598
1.47
7.47
1.1
1.1
1.32
2.44
iu/ml
—
5
37
313
2132
1.40
7.41
1.1
1.1
1.13
2.09
iu/ml
—
5
45
202
1337
1.52
7.39
1.1
1.1
2.75
1.98
iu/ml
0.52
12
25
437
2301
1.33
7.33
1.1
1.1
1.65
2.02
iu/ml
0.31
17
60
14
26
5.60
7.32
1.1
1.1
—
—
—
0
0
134
683
1.68
7.27
1.1
1.1
2.40
2.17
iu/ml
0.09
11
28
153
528
1.64
7.08
1.2
1.1
1.80
2.26
iu/ml
—
6
13
191
1086
1.53
7.07
1.2
1.1
—
2.11
—
0
12
208
1399
1.49
7.06
1.1
1.1
0.70
2.23
iu/ml
—
5
38
697
3984
1.25
7.04
1.2
1.1
2.09
1.93
iu/ml
0.07
12
90
146
909
1.62
7.03
1.2
1.1
1.71
2.33
iu/ml
—
5
8
469
2487
1.31
6.96
1.1
1.1
1.65
2.02
iu/ml
0.31
17
60
81
428
1.91
6.94
1.2
1.1
1.29
2.89
iu/ml
—
6
6
702
4103
1.24
6.87
1.1
1.1
2.11
1.88
iu/ml
0.14
14
82
631
2834
1.26
6.83
1.1
1.1
1.56
1.77
iu/ml
0.18
11
42
364
1351
1.37
6.81
1.1
1.1
2.69
2.12
iu/ml
—
9
29
272
1104
1.43
6.81
1.2
1.1
2.17
1.81
iu/ml
—
8
12
243
1690
1.43
6.71
1.1
1.1
4.03
2.00
iu/ml
—
5
39
849
3995
1.22
6.68
1.1
1.1
1.09
2.12
iu/ml
2.82
15
86
286
1572
1.40
6.64
1.2
1.1
2.27
1.32
iu/ml
—
10
38
178
730
1.55
6.64
1.2
1.1
1.65
2.12
iu/ml
—
7
18
846
3481
1.22
6.54
1.2
1.1
1.35
2.04
iu/ml
1.03
16
69
106
1759
0.60
6.48
1.2
1.1
2.30
1.78
iu/ml
—
5
20
10
15
7.13
6.40
1.3
1.0
—
—
—
0
0
329
1734
1.36
6.38
1.2
1.1
2.08
1.36
iu/ml
0.56
13
38
57
275
2.09
6.34
1.1
1.1
—
2.18
—
0
7
237
1672
1.42
6.30
1.2
1.1
1.45
2.25
iu/ml
—
8
37
158
1031
1.54
6.26
1.1
1.1
3.26
2.16
iu/ml
—
6
14
215
1492
1.45
6.26
1.1
1.1
1.80
2.61
iu/ml
—
9
30
107
1755
0.61
6.26
1.2
1.1
1.98
1.85
iu/ml
—
6
19
738
3491
1.22
6.16
1.2
1.1
1.42
1.98
iu/ml
0.42
13
80
199
1369
1.46
6.11
1.2
1.1
1.71
2.37
iu/ml
—
5
11
221
1449
1.43
6.03
1.1
1.1
—
1.97
—
0
14
17
44
3.96
6.03
1.2
1.2
—
—
—
0
0
9
6
15.83
5.98
1.7
1.3
—
—
—
0
0
24
79
3.10
5.96
1.0
1.1
—
—
—
0
0
166
1108
1.50
5.92
1.2
1.1
3.16
1.94
iu/ml
—
7
32
238
1702
1.40
5.89
1.2
1.1
1.45
2.26
iu/ml
—
8
37
129
816
1.59
5.89
1.1
1.1
1.24
1.84
iu/ml
—
6
16
83
424
1.79
5.79
1.2
1.1
0.91
2.61
iu/ml
—
6
17
636
2762
1.24
5.78
1.1
1.1
1.34
1.68
iu/ml
—
7
38
191
1321
1.45
5.73
1.1
1.1
0.70
2.17
iu/ml
—
5
21
15
37
4.20
5.69
1.1
1.0
—
—
—
0
0
292
1162
1.37
5.69
1.1
1.1
1.03
2.35
iu/ml
—
6
14
262
1876
1.37
5.67
1.1
1.1
2.36
2.03
iu/ml
—
8
51
269
1927
1.37
5.67
1.1
1.1
2.01
1.95
iu/ml
—
10
54
661
3816
1.22
5.66
1.1
1.1
1.82
2.05
iu/ml
0.17
19
71
57
288
1.99
5.64
1.1
1.1
—
2.36
—
0
5
489
2299
1.27
5.63
1.2
1.1
1.56
2.20
iu/ml
0.52
13
31
59
302
1.96
5.62
1.1
1.2
—
2.66
—
0
10
814
3395
1.20
5.56
1.2
1.1
1.43
2.07
iu/ml
0.58
13
81
8
5
17.81
5.55
1.3
1.0
—
—
—
0
0
18
52
3.55
5.50
1.2
1.2
—
—
—
0
0
837
3919
1.20
5.46
1.1
1.1
1.64
2.10
iu/ml
0.50
16
81
184
1204
1.44
5.33
1.1
1.1
3.54
2.04
iu/ml
—
5
51
12
26
4.74
5.30
1.2
1.2
—
—
—
0
0
71
395
1.81
5.28
1.1
1.1
—
2.57
—
0
7
8
6
14.80
5.21
1.3
1.0
—
—
—
0
0
314
1187
1.33
5.18
1.1
1.1
1.80
1.81
iu/ml
—
6
12
285
1748
1.34
5.13
1.1
1.1
1.40
2.13
iu/ml
—
10
55
186
1100
1.43
5.06
1.1
1.1
2.02
1.91
iu/ml
0.06
16
41
147
820
1.49
5.06
1.1
1.1
1.02
2.39
iu/ml
—
6
31
724
3174
1.20
5.05
1.1
1.1
1.36
2.20
iu/ml
1.66
12
77
477
2491
1.25
5.03
1.2
1.1
1.38
1.89
iu/ml
0.60
15
62
612
3126
1.22
5.02
1.2
1.1
1.23
2.07
iu/ml
1.37
11
71
21
71
2.99
5.00
1.1
1.1
—
—
—
0
0
456
2335
1.26
4.98
1.1
1.1
2.07
1.89
iu/ml
0.10
13
54
177
1242
1.43
4.97
1.2
1.1
3.41
1.84
iu/ml
—
7
37
15
41
3.75
4.96
1.3
1.0
—
—
—
0
0
447
2360
1.25
4.87
1.2
1.1
1.28
2.02
iu/ml
—
6
31
754
4134
1.19
4.86
1.1
1.1
1.77
1.96
iu/ml
0.10
14
90
22
78
2.86
4.84
1.1
1.1
—
—
—
0
0
216
1522
1.37
4.83
1.2
1.1
2.07
1.96
iu/ml
—
9
41
84
506
1.67
4.76
1.2
1.1
1.10
2.55
iu/ml
—
6
7
66
372
1.78
4.74
1.2
1.1
3.82
2.63
iu/ml
—
5
14
509
2906
1.23
4.72
1.1
1.1
1.65
1.98
iu/ml
—
9
76
19
63
3.08
4.71
1.2
1.1
—
—
—
0
0
361
2618
1.27
4.70
1.2
1.1
1.24
2.12
iu/ml
1.41
11
70
12
29
4.24
4.66
1.2
1.2
—
—
—
0
0
281
1880
1.32
4.65
1.1
1.1
2.37
1.87
iu/ml
—
9
64
17
53
3.27
4.65
1.0
1.1
—
—
—
0
0
211
1537
1.37
4.64
1.1
1.1
3.39
2.05
iu/ml
—
5
44
559
2811
1.22
4.60
1.1
1.1
2.05
1.94
iu/ml
0.05
11
62
22
80
2.78
4.59
1.2
1.1
—
—
—
0
0
526
2954
1.22
4.58
1.1
1.1
1.52
1.94
iu/ml
—
10
78
504
2584
1.23
4.55
1.1
1.1
1.02
2.04
iu/ml
2.44
19
64
86
528
1.64
4.54
1.2
1.1
—
1.56
—
0
5
792
3362
1.18
4.54
1.2
1.1
1.25
2.08
iu/ml
1.73
13
78
119
615
1.52
4.50
1.1
1.1
2.09
2.06
iu/ml
0.01
13
29
15
44
3.48
4.50
1.1
1.1
—
—
—
0
0
116
766
1.52
4.49
1.2
1.1
1.10
2.34
iu/ml
—
6
11
13
35
3.78
4.38
1.0
1.1
—
—
—
0
0
7
6
12.44
4.34
1.1
1.0
—
—
—
0
0
10
22
4.66
4.33
1.1
1.2
—
—
—
0
0
12
31
3.96
4.29
1.0
1.1
—
—
—
0
0
347
1663
1.27
4.24
1.1
1.1
3.29
1.99
iu/ml
—
6
29
13
36
3.69
4.23
1.2
1.2
—
—
—
0
0
562
2557
1.21
4.23
1.1
1.1
1.32
2.35
iu/ml
1.93
15
52
222
1665
1.34
4.22
1.1
1.1
1.39
2.01
iu/ml
—
5
25
48
255
1.90
4.21
1.1
1.1
—
2.10
—
0
6
115
768
1.50
4.20
1.2
1.1
2.99
2.02
iu/ml
—
5
29
107
1580
0.67
4.17
1.2
1.1
1.98
1.71
iu/ml
—
6
21
68
1117
0.61
4.16
1.1
1.1
—
1.46
—
0
22
163
991
1.40
4.15
1.1
1.1
1.88
2.13
iu/ml
0.14
11
39
146
1026
1.43
4.14
1.2
1.1
2.52
1.93
iu/ml
—
6
28
10
23
4.47
4.12
1.0
1.0
—
—
—
0
0
246
1467
1.32
4.11
1.1
1.1
1.18
2.07
iu/ml
—
8
45
85
535
1.60
4.11
1.2
1.1
2.41
2.90
iu/ml
—
5
6
7
7
10.64
4.08
1.3
1.9
—
—
—
0
0
7
7
10.59
4.07
1.0
1.0
—
—
—
0
0
603
3299
1.19
4.06
1.1
1.1
1.76
2.03
iu/ml
0.21
17
75
7
7
10.44
4.05
1.1
1.0
—
—
—
0
0
5
0
+∞
4.04
1.8
0.0
—
—
—
0
0
184
1075
1.37
4.03
1.1
1.1
0.99
2.11
iu/ml
—
7
46
146
1032
1.42
4.03
1.2
1.1
2.52
1.93
iu/ml
—
6
28
308
2415
1.27
3.97
1.2
1.1
0.88
2.04
iu/ml
—
10
34
12
33
3.71
3.95
1.2
1.1
—
—
—
0
0
197
1181
1.35
3.86
1.1
1.1
1.01
2.10
iu/ml
—
8
47
287
1853
1.28
3.85
1.1
1.1
1.51
1.84
iu/ml
0.29
11
59
7
8
9.16
3.82
1.0
1.0
—
—
—
0
0
448
3002
1.21
3.80
1.2
1.1
1.81
2.00
iu/ml
0.11
12
74
284
2222
1.27
3.76
1.1
1.1
0.85
2.02
iu/ml
—
6
52
92
1359
0.67
3.75
1.1
1.1
—
1.67
—
0
26
161
1110
1.38
3.72
1.1
1.1
3.54
2.08
iu/ml
—
5
49
361
2501
1.24
3.71
1.2
1.1
1.24
1.89
iu/ml
0.92
11
61
186
1389
1.34
3.71
1.2
1.1
3.30
2.10
iu/ml
—
8
35
11
30
3.71
3.65
1.1
1.2
—
—
—
0
0
438
2263
1.21
3.62
1.2
1.1
1.52
1.97
iu/ml
—
8
59
396
2611
1.22
3.61
1.1
1.1
1.84
1.95
iu/ml
0.05
15
66
100
830
0.68
3.60
1.0
1.1
—
3.19
—
0
6
182
1013
1.35
3.58
1.2
1.1
—
2.62
—
0
11
385
2413
1.22
3.56
1.1
1.1
2.56
2.11
iu/ml
0.29
11
50
10
26
3.92
3.54
1.2
1.2
—
—
—
0
0
13
41
3.24
3.52
1.2
1.2
—
—
—
0
0
98
909
0.68
3.51
1.1
1.1
3.07
1.83
iu/ml
—
8
46
598
3456
1.18
3.51
1.1
1.1
1.44
2.05
iu/ml
0.42
12
68
11
31
3.63
3.51
1.3
1.2
—
—
—
0
0
15
52
2.92
3.47
1.1
1.1
—
—
—
0
0
62
378
1.65
3.47
1.1
1.1
—
3.09
—
0
5
78
820
0.65
3.41
1.1
1.1
0.96
2.33
iu/ml
—
5
43
400
2930
1.21
3.36
1.1
1.1
2.23
2.00
iu/ml
0.11
11
73
107
972
0.70
3.34
1.1
1.1
3.06
1.83
iu/ml
—
8
46
305
2431
1.24
3.28
1.2
1.1
2.06
2.08
iu/ml
—
6
62
167
1251
1.34
3.28
1.1
1.1
0.90
1.79
iu/ml
—
9
14
132
931
1.39
3.25
1.2
1.1
2.99
2.14
iu/ml
—
5
33
7
11
6.67
3.23
1.3
1.4
—
—
—
0
0
194
1123
1.31
3.21
1.1
1.1
1.79
2.34
iu/ml
—
6
38
358
2904
1.21
3.20
1.1
1.1
2.95
1.51
iu/ml
—
10
40
172
1200
1.33
3.18
1.1
1.1
1.78
1.89
iu/ml
—
6
51
150
1057
1.35
3.16
1.1
1.1
3.54
2.08
iu/ml
—
5
49
244
1691
1.26
3.15
1.1
1.1
1.52
2.21
iu/ml
—
8
50
343
2728
1.22
3.14
1.1
1.1
1.59
1.99
iu/ml
—
8
68
115
631
1.42
3.13
1.2
1.1
1.99
2.09
iu/ml
—
8
25
80
533
1.51
3.10
1.1
1.1
1.14
2.59
iu/ml
—
5
5
8
16
5.14
3.08
1.1
1.0
—
—
—
0
0
106
1446
0.71
3.07
1.1
1.1
—
1.64
—
0
27
5
5
10.72
3.03
1.6
1.0
—
—
—
0
0
5
5
10.53
3.02
1.2
1.0
—
—
—
0
0
5
5
10.51
3.01
1.0
1.0
—
—
—
0
0
5
5
10.27
3.00
1.2
1.0
—
—
—
0
0
15
57
2.67
2.98
1.1
1.1
—
—
—
0
0
155
986
1.33
2.96
1.2
1.1
3.24
1.89
iu/ml
—
6
37
10
30
3.41
2.93
1.3
1.1
—
—
—
0
0
282
2277
1.23
2.89
1.1
1.1
1.47
2.23
iu/ml
—
5
40
16
64
2.53
2.89
1.1
1.1
—
—
—
0
0
376
3103
1.19
2.88
1.1
1.1
2.95
1.53
iu/ml
—
10
43
123
901
1.37
2.88
1.2
1.1
—
1.55
—
0
18
301
2428
1.22
2.83
1.2
1.1
1.24
2.01
iu/ml
1.20
11
62
8
18
4.56
2.82
1.4
1.1
—
—
—
0
0
235
1723
1.25
2.81
1.1
1.1
2.21
2.06
iu/ml
—
8
50
28
144
1.96
2.81
1.0
1.1
—
—
—
0
0
23
110
2.11
2.80
1.2
1.1
—
—
—
0
0
10
31
3.28
2.79
1.4
1.1
—
—
—
0
0
186
1386
1.28
2.77
1.2
1.1
3.30
1.59
iu/ml
—
8
36
233
1870
1.25
2.77
1.1
1.1
1.32
2.24
iu/ml
—
6
38
172
751
1.31
2.76
1.1
1.1
2.26
2.25
iu/ml
—
6
23
7
14
5.09
2.74
1.1
1.1
—
—
—
0
0
6
10
6.23
2.73
1.0
1.0
—
—
—
0
0
6
10
6.17
2.72
1.2
1.0
—
—
—
0
0
8
19
4.30
2.69
1.0
1.3
—
—
—
0
0
95
675
1.41
2.69
1.1
1.1
—
2.56
—
0
7
17
73
2.36
2.67
1.2
1.1
—
—
—
0
0
12
43
2.83
2.66
1.3
1.2
—
—
—
0
0
66
438
1.51
2.66
1.1
1.1
2.99
2.50
iu/ml
—
5
15
7
15
4.79
2.62
1.0
1.3
—
—
—
0
0
328
1897
1.20
2.61
1.1
1.1
2.77
1.94
iu/ml
—
7
43
519
2789
1.16
2.57
1.1
1.1
1.76
2.19
iu/ml
—
9
43
12
44
2.76
2.56
1.0
1.1
—
—
—
0
0
167
1305
1.28
2.53
1.2
1.1
2.28
2.04
iu/ml
—
5
38
28
499
0.56
2.50
1.0
1.1
—
1.20
—
0
8
7
16
4.51
2.50
1.0
1.1
—
—
—
0
0
12
45
2.70
2.46
1.3
1.1
—
—
—
0
0
13
51
2.59
2.46
1.4
1.1
—
—
—
0
0
6
12
5.15
2.42
1.0
1.0
—
—
—
0
0
6
12
5.13
2.42
1.0
1.0
—
—
—
0
0
101
741
1.37
2.41
1.1
1.1
—
1.13
—
0
10
318
2668
1.19
2.39
1.1
1.1
1.09
2.28
iu/ml
—
7
58
36
212
1.71
2.39
1.1
1.1
—
1.31
—
0
5
8
22
3.71
2.38
1.3
1.0
—
—
—
0
0
7
17
4.22
2.38
1.4
1.0
—
—
—
0
0
21
400
0.52
2.37
1.2
1.1
—
3.16
—
0
5
344
2552
1.18
2.37
1.2
1.1
1.76
2.05
iu/ml
—
10
60
67
390
1.47
2.37
1.1
1.1
2.52
2.25
iu/ml
—
5
10
66
451
1.47
2.35
1.1
1.1
—
3.16
—
0
5
6
13
4.78
2.30
1.0
1.0
—
—
—
0
0
331
2118
1.18
2.28
1.1
1.1
1.31
1.98
iu/ml
0.96
13
56
45
285
1.59
2.27
1.2
1.1
—
3.05
—
0
5
441
3015
0.87
2.27
1.1
1.1
3.04
1.68
iu/ml
—
9
63
128
984
1.30
2.25
1.2
1.1
1.23
1.95
iu/ml
—
5
27
18
353
0.51
2.24
1.2
1.1
—
3.16
—
0
5
670
3562
1.12
2.24
1.2
1.1
2.07
1.90
iu/ml
0.11
14
73
9
29
3.16
2.24
1.2
1.0
—
—
—
0
0
14
60
2.36
2.23
1.3
1.1
—
—
—
0
0
497
3651
1.14
2.22
1.1
1.1
0.87
2.05
iu/ml
2.98
12
76
426
2570
1.16
2.20
1.1
1.1
1.22
2.20
iu/ml
—
5
27
8
24
3.40
2.19
1.0
1.0
—
—
—
0
0
6
14
4.43
2.17
1.0
1.2
—
—
—
0
0
72
509
1.42
2.17
1.2
1.1
—
2.54
—
0
7
6
14
4.36
2.16
1.2
1.0
—
—
—
0
0
9
30
3.05
2.16
1.3
1.1
—
—
—
0
0
14
61
2.32
2.15
1.1
1.1
—
—
—
0
0
6
165
0.36
2.14
1.0
1.1
—
2.63
—
0
5
13
55
2.39
2.13
1.2
1.1
—
—
—
0
0
5
10
5.21
2.09
1.4
1.4
—
—
—
0
0
64
447
1.44
2.07
1.2
1.1
—
2.38
—
0
6
0
56
0.00
2.07
0.0
1.1
—
—
—
0
0
73
480
1.41
2.07
1.1
1.1
—
1.79
—
0
5
129
978
1.28
2.05
1.1
1.1
0.98
2.39
iu/ml
—
6
46
15
301
0.50
2.04
1.0
1.1
—
1.73
—
0
11
40
254
1.58
2.03
1.3
1.1
—
2.85
—
0
5
8
26
3.13
2.03
1.3
1.0
—
—
—
0
0
11
44
2.53
2.02
1.0
1.1
—
—
—
0
0
14
63
2.25
2.02
1.1
1.1
—
—
—
0
0
392
3171
1.15
1.99
1.1
1.1
0.97
2.00
iu/ml
—
5
53
7
21
3.38
1.97
1.7
1.1
—
—
—
0
0
19
98
1.96
1.96
1.4
1.1
—
—
—
0
0
8
27
3.03
1.95
1.5
1.1
—
—
—
0
0
111
854
1.30
1.95
1.1
1.1
—
3.16
—
0
6
8
27
3.01
1.94
1.1
1.1
—
—
—
0
0
9
33
2.77
1.94
1.1
1.2
—
—
—
0
0
7
144
0.40
1.92
1.0
1.2
—
1.25
—
0
9
669
3591
1.11
1.91
1.2
1.1
2.07
1.90
iu/ml
0.11
14
73
0
51
0.00
1.89
0.0
1.2
—
—
—
0
0
14
65
2.17
1.89
1.2
1.1
—
—
—
0
0
14
65
2.17
1.89
1.0
1.0
—
—
—
0
0
618
3289
1.12
1.88
1.2
1.1
2.07
1.94
iu/ml
0.08
14
71
8
28
2.91
1.87
1.0
1.0
—
—
—
0
0
8
28
2.90
1.87
1.0
1.0
—
—
—
0
0
119
556
1.29
1.87
1.2
1.1
0.84
1.76
iu/ml
—
6
8
6
17
3.60
1.85
1.0
1.1
—
—
—
0
0
6
17
3.58
1.84
1.2
1.1
—
—
—
0
0
5
12
4.27
1.84
1.0
1.3
—
—
—
0
0
5
12
4.26
1.83
1.4
1.2
—
—
—
0
0
7
23
3.09
1.81
1.0
1.1
—
—
—
0
0
8
29
2.79
1.80
1.1
1.2
—
—
—
0
0
11
47
2.37
1.79
1.3
1.1
—
—
—
0
0
107
1132
0.78
1.77
1.1
1.1
2.85
2.12
iu/ml
—
6
44
9
36
2.53
1.75
1.0
1.2
—
—
—
0
0
416
3322
1.13
1.74
1.2
1.1
1.65
2.13
iu/ml
—
7
61
343
1991
1.15
1.73
1.1
1.1
1.96
1.96
iu/ml
—
10
60
8
30
2.71
1.73
1.1
1.1
—
—
—
0
0
7
24
2.97
1.73
1.0
1.0
—
—
—
0
0
5
13
3.92
1.72
1.2
1.5
—
—
—
0
0
5
13
3.89
1.72
1.4
1.0
—
—
—
0
0
133
1068
1.25
1.72
1.2
1.1
1.40
2.18
iu/ml
—
6
20
17
89
1.92
1.70
1.0
1.1
—
—
—
0
0
98
760
1.29
1.70
1.1
1.1
1.20
2.66
iu/ml
—
5
18
459
3048
0.89
1.69
1.1
1.1
2.99
1.66
iu/ml
—
8
56
10
42
2.42
1.69
1.4
1.2
—
—
—
0
0
8
180
0.44
1.69
1.0
1.1
—
—
—
0
0
12
55
2.20
1.68
1.1
1.1
—
—
—
0
0
45
308
1.47
1.68
1.2
1.1
—
2.82
—
0
8
227
1927
1.18
1.68
1.2
1.1
1.25
2.39
iu/ml
—
7
45
6
19
3.20
1.67
1.0
1.0
—
—
—
0
0
8
31
2.61
1.66
1.0
1.2
—
—
—
0
0
7
25
2.84
1.66
1.4
1.3
—
—
—
0
0
7
25
2.84
1.66
1.3
1.2
—
—
—
0
0
17
90
1.90
1.66
1.1
1.1
—
—
—
0
0
337
1896
1.15
1.65
1.1
1.1
1.65
2.01
iu/ml
—
7
56
460
3049
0.89
1.65
1.1
1.1
2.98
1.66
iu/ml
—
8
56
138
1119
1.23
1.64
1.2
1.1
1.40
2.18
iu/ml
—
6
20
5
14
3.63
1.62
1.2
1.1
—
—
—
0
0
156
1283
1.22
1.62
1.2
1.1
1.40
2.00
iu/ml
—
6
23
357
2967
1.14
1.61
1.2
1.1
1.76
1.95
iu/ml
—
10
61
8
32
2.53
1.60
1.0
1.2
—
—
—
0
0
6
20
3.06
1.59
1.2
1.2
—
—
—
0
0
6
20
3.05
1.59
1.0
1.3
—
—
—
0
0
143
1026
1.23
1.58
1.1
1.1
0.89
2.12
iu/ml
—
6
40
56
405
1.39
1.57
1.1
1.1
—
2.16
—
0
8
344
2898
1.14
1.54
1.2
1.1
1.76
1.97
iu/ml
—
10
60
364
2302
1.13
1.54
1.1
1.1
2.31
1.98
iu/ml
—
10
65
140
656
1.23
1.54
1.1
1.1
2.28
0.66
iu/ml
—
5
8
7
27
2.63
1.52
1.1
1.0
—
—
—
0
0
6
21
2.90
1.51
1.3
1.0
—
—
—
0
0
6
21
2.90
1.51
1.2
1.1
—
—
—
0
0
7
28
2.54
1.46
1.1
1.1
—
—
—
0
0
7
28
2.54
1.46
1.1
1.1
—
—
—
0
0
5
16
3.18
1.44
1.8
1.4
—
—
—
0
0
6
22
2.77
1.44
1.2
1.0
—
—
—
0
0
6
22
2.76
1.44
1.0
1.1
—
—
—
0
0
6
22
2.76
1.44
1.2
1.2
—
—
—
0
0
39
269
1.45
1.43
1.2
1.1
—
2.90
—
0
5
47
336
1.40
1.43
1.2
1.1
—
2.20
—
0
7
132
1087
1.22
1.42
1.1
1.1
1.30
2.14
iu/ml
—
6
20
7
29
2.44
1.40
1.1
1.2
—
—
—
0
0
11
53
2.10
1.39
1.2
1.0
—
—
—
0
0
51
372
1.38
1.39
1.1
1.1
—
3.19
—
0
5
312
2758
1.13
1.39
1.1
1.1
1.48
2.11
iu/ml
—
9
51
282
2195
1.14
1.38
1.1
1.1
2.06
2.09
iu/ml
—
9
39
9
41
2.22
1.37
1.1
1.2
—
—
—
0
0
5
17
3.01
1.37
1.4
1.1
—
—
—
0
0
5
17
2.98
1.36
1.0
1.1
—
—
—
0
0
5
17
2.97
1.36
1.0
1.1
—
—
—
0
0
398
2230
1.12
1.35
1.2
1.1
1.58
1.98
iu/ml
—
7
59
6
24
2.54
1.31
1.0
1.2
—
—
—
0
0
6
24
2.53
1.31
1.0
1.1
—
—
—
0
0
6
24
2.53
1.31
1.0
1.2
—
—
—
0
0
8
34
2.38
1.30
1.0
1.1
—
—
—
0
0
5
18
2.81
1.29
1.0
1.1
—
—
—
0
0
5
18
2.81
1.29
1.0
1.1
—
—
—
0
0
12
62
1.95
1.28
1.0
1.1
—
—
—
0
0
11
55
2.02
1.28
1.1
1.1
—
—
—
0
0
89
581
1.25
1.27
1.1
1.1
2.22
2.12
iu/ml
—
7
22
106
895
0.82
1.26
1.1
1.1
0.86
2.27
iu/ml
—
6
45
435
2472
1.11
1.26
1.2
1.1
1.36
2.10
iu/ml
0.86
11
66
383
3305
1.11
1.26
1.2
1.1
1.40
2.11
iu/ml
—
8
50
8
36
2.24
1.24
1.0
1.2
—
—
—
0
0
245
1623
1.14
1.24
1.1
1.1
2.37
1.85
iu/ml
0.27
11
51
13
210
0.57
1.23
1.0
1.1
—
1.14
—
0
8
10
49
2.07
1.23
1.2
1.1
—
—
—
0
0
5
19
2.65
1.22
1.2
1.1
—
—
—
0
0
409
1931
1.11
1.20
1.1
1.1
1.08
2.01
iu/ml
—
10
24
11
57
1.95
1.17
1.1
1.1
—
—
—
0
0
13
202
0.58
1.16
1.0
1.1
—
1.07
—
0
5
84
677
1.24
1.16
1.2
1.1
—
1.36
—
0
5
49
368
1.34
1.15
1.1
1.1
—
2.58
—
0
7
8
39
2.07
1.15
1.5
1.2
—
—
—
0
0
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
48
566
0.76
1.15
1.1
1.1
—
2.21
—
0
27
8
40
2.01
1.12
1.0
1.2
—
—
—
0
0
7
31
2.28
1.11
1.3
1.1
—
—
—
0
0
50
652
0.77
1.10
1.1
1.1
—
1.37
—
0
6
7
31
2.27
1.10
1.1
1.1
—
—
—
0
0
5
21
2.41
1.09
1.8
1.3
—
—
—
0
0
5
21
2.41
1.09
1.6
1.0
—
—
—
0
0
5
21
2.41
1.09
1.2
1.0
—
—
—
0
0
5
21
2.41
1.09
1.2
1.2
—
—
—
0
0
5
21
2.40
1.09
1.2
1.0
—
—
—
0
0
7
32
2.21
1.08
1.3
1.2
—
—
—
0
0
7
32
2.21
1.08
1.0
1.0
—
—
—
0
0
7
32
2.21
1.08
1.3
1.2
—
—
—
0
0
7
32
2.21
1.08
1.0
1.3
—
—
—
0
0
40
296
1.35
1.05
1.1
1.1
3.15
1.83
iu/ml
—
5
10
9
46
1.97
1.04
1.0
1.2
—
—
—
0
0
5
22
2.30
1.04
1.0
1.0
—
—
—
0
0
5
22
2.30
1.04
1.4
1.3
—
—
—
0
0
556
3068
1.08
1.03
1.2
1.1
2.18
1.87
iu/ml
0.17
11
67
120
976
0.85
1.02
1.1
1.1
0.84
2.34
iu/ml
—
7
49
64
730
0.80
1.02
1.0
1.1
—
2.53
—
0
8
9
48
1.89
1.01
1.1
1.2
—
—
—
0
0
9
48
1.89
1.01
1.1
1.1
—
—
—
0
0
7
35
2.03
1.00
1.4
1.0
—
—
—
0
0
5
23
2.19
0.98
1.4
1.2
—
—
—
0
0
14
84
1.68
0.98
1.3
1.1
—
—
—
0
0
222
1686
0.89
0.98
1.2
1.1
1.99
2.04
iu/ml
—
7
55
0
29
0.00
0.98
0.0
1.3
—
—
—
0
0
563
3092
1.08
0.97
1.2
1.1
2.18
1.95
iu/ml
0.12
11
68
152
1261
0.87
0.95
1.1
1.1
0.97
2.19
iu/ml
—
7
54
7
37
1.92
0.94
1.4
1.0
—
—
—
0
0
11
62
1.79
0.94
1.1
1.1
—
—
—
0
0
398
3524
1.09
0.93
1.2
1.1
0.87
2.14
iu/ml
—
9
62
52
409
1.27
0.93
1.1
1.1
—
3.16
—
0
5
385
1916
1.09
0.92
1.1
1.1
1.16
2.01
iu/ml
—
9
24
6
28
2.16
0.92
1.0
1.0
—
—
—
0
0
14
86
1.64
0.91
1.1
1.1
—
—
—
0
0
6
29
2.09
0.89
1.2
1.0
—
—
—
0
0
296
2520
1.10
0.89
1.2
1.1
1.65
2.11
iu/ml
—
7
45
77
637
1.21
0.89
1.2
1.1
—
1.08
—
0
5
8
42
1.92
0.89
1.1
1.2
—
—
—
0
0
282
2946
0.91
0.89
1.1
1.1
1.42
2.09
iu/ml
—
8
60
6
29
2.05
0.88
1.2
1.4
—
—
—
0
0
6
30
2.02
0.87
1.2
1.1
—
—
—
0
0
43
549
0.78
0.87
1.3
1.1
—
2.38
—
0
6
162
1404
1.14
0.86
1.1
1.1
1.31
2.22
iu/ml
—
7
28
56
450
1.25
0.85
1.2
1.1
—
2.50
—
0
18
18
120
1.51
0.85
1.1
1.1
—
—
—
0
0
107
996
0.86
0.85
1.1
1.1
0.60
1.91
iu/ml
—
5
48
6
31
1.95
0.85
1.2
1.0
—
—
—
0
0
226
1460
1.11
0.83
1.2
1.1
2.61
2.09
iu/ml
—
7
51
0
22
0.00
0.80
0.0
1.2
—
—
—
0
0
261
1763
1.10
0.80
1.1
1.1
2.56
1.78
iu/ml
—
10
55
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
17
114
1.50
0.79
1.1
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
6
33
1.83
0.79
1.0
1.2
—
—
—
0
0
69
573
1.21
0.79
1.1
1.1
—
2.03
—
0
10
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
26
190
1.37
0.79
1.1
1.1
—
—
—
0
0
40
313
1.28
0.77
1.1
1.1
—
2.92
—
0
5
553
3095
1.07
0.77
1.2
1.1
2.18
1.87
iu/ml
0.17
11
67
35
269
1.30
0.77
1.1
1.1
—
1.72
—
0
9
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
10
59
1.71
0.76
1.3
1.2
—
—
—
0
0
81
680
1.18
0.76
1.2
1.1
—
2.17
—
0
7
77
909
0.85
0.75
1.2
1.1
—
2.61
—
0
7
11
67
1.65
0.75
1.1
1.0
—
—
—
0
0
5
24
2.10
0.75
1.0
1.1
—
—
—
0
0
5
24
2.10
0.75
1.4
1.2
—
—
—
0
0
5
24
2.10
0.75
1.4
1.1
—
—
—
0
0
230
1644
1.10
0.75
1.1
1.1
2.86
1.79
iu/ml
—
10
60
9
54
1.68
0.74
1.1
1.1
—
—
—
0
0
5
25
2.02
0.73
1.0
1.2
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
5
25
2.01
0.73
1.0
1.1
—
—
—
0
0
7
39
1.81
0.73
1.0
1.1
—
—
—
0
0
13
84
1.56
0.72
1.1
1.1
—
—
—
0
0
17
117
1.46
0.72
1.1
1.1
—
—
—
0
0
12
71
1.59
0.72
1.1
1.2
—
—
—
0
0
59
489
1.21
0.71
1.2
1.1
—
0.72
—
0
5
5
26
1.94
0.71
1.2
1.2
—
—
—
0
0
5
26
1.94
0.71
1.4
1.2
—
—
—
0
0
5
26
1.94
0.71
1.4
1.2
—
—
—
0
0
5
26
1.93
0.71
1.0
1.1
—
—
—
0
0
15
101
1.49
0.70
1.0
1.1
—
—
—
0
0
106
925
1.15
0.70
1.1
1.1
—
2.19
—
0
7
9
143
0.63
0.70
1.2
1.1
—
—
—
0
0
7
42
1.68
0.68
1.3
1.2
—
—
—
0
0
279
1904
1.08
0.66
1.1
1.1
2.78
1.80
iu/ml
—
9
56
97
846
1.15
0.66
1.2
1.1
—
1.90
—
0
9
63
745
0.84
0.66
1.2
1.1
—
2.61
—
0
7
10
62
1.62
0.65
1.3
1.2
—
—
—
0
0
139
714
1.12
0.65
1.1
1.1
—
1.76
—
0
8
26
338
0.77
0.64
1.3
1.1
—
2.79
—
0
6
567
3275
1.06
0.64
1.1
1.1
1.90
1.91
iu/ml
0.01
13
71
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
45
368
1.23
0.63
1.1
1.1
0.74
2.17
iu/ml
—
5
16
64
543
1.18
0.62
1.1
1.1
—
2.52
—
0
16
519
3255
0.94
0.61
1.1
1.1
2.79
1.61
iu/ml
—
10
64
5
30
1.68
0.61
1.0
1.2
—
—
—
0
0
124
1106
1.12
0.61
1.1
1.1
2.24
1.91
iu/ml
—
5
12
8
50
1.61
0.61
1.1
1.2
—
—
—
0
0
214
1626
1.09
0.61
1.1
1.1
2.05
1.73
iu/ml
0.15
13
52
0
20
0.00
0.60
0.0
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—
—
—
0
0
0
20
0.00
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0.0
1.2
—
—
—
0
0
630
3640
1.05
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1.2
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2.10
1.88
iu/ml
0.15
14
74
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
66
762
0.86
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1.1
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—
1.49
—
0
7
8
52
1.55
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1.0
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—
—
—
0
0
14
97
1.45
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1.1
1.1
—
—
—
0
0
220
1612
1.09
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1.1
1.1
2.86
1.79
iu/ml
—
10
60
10
64
1.57
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1.6
1.1
—
—
—
0
0
65
556
1.17
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1.2
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0.96
2.90
iu/ml
—
5
6
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
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0.0
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—
—
—
0
0
0
23
0.00
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0.0
1.2
—
—
—
0
0
8
53
1.52
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1.3
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—
—
—
0
0
126
1130
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1.2
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2.40
2.06
iu/ml
—
5
19
6
35
1.72
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1.2
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—
—
—
0
0
6
35
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1.0
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—
—
—
0
0
6
35
1.72
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1.2
1.2
—
—
—
0
0
65
557
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—
2.41
—
0
14
448
3859
1.06
0.57
1.2
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0.87
2.08
iu/ml
4.24
14
72
215
1564
1.09
0.56
1.1
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2.85
1.78
iu/ml
—
10
59
6
37
1.63
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1.0
1.2
—
—
—
0
0
198
1268
1.09
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1.1
1.1
2.80
2.17
iu/ml
—
8
48
248
2000
1.08
0.54
1.1
1.1
2.06
1.96
iu/ml
—
7
68
17
125
1.36
0.53
1.2
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—
—
—
0
0
6
39
1.55
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1.0
1.1
—
—
—
0
0
6
96
0.62
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1.3
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—
—
—
0
0
14
100
1.41
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1.1
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—
—
—
0
0
105
1170
0.90
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1.2
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2.29
2.25
iu/ml
—
6
29
15
109
1.38
0.51
1.1
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—
—
—
0
0
16
118
1.36
0.50
1.2
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—
—
—
0
0
37
444
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—
2.75
—
0
5
442
3841
1.05
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1.2
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0.87
2.08
iu/ml
4.24
14
72
441
2625
1.05
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1.1
1.1
1.56
2.12
iu/ml
—
7
28
7
46
1.53
0.48
1.1
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—
—
—
0
0
90
805
1.12
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1.1
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—
1.34
—
0
6
77
867
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1.2
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—
2.34
—
0
11
5
81
0.61
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1.6
1.1
—
—
—
0
0
7
50
1.41
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1.6
1.0
—
—
—
0
0
585
3431
1.04
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1.1
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2.36
1.91
iu/ml
0.28
15
74
64
563
1.14
0.44
1.2
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—
1.73
—
0
6
18
139
1.30
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1.1
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—
—
—
0
0
5
31
1.62
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1.6
1.0
—
—
—
0
0
5
31
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—
—
—
0
0
5
31
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—
—
—
0
0
6
92
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1.0
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—
—
—
0
0
154
1093
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1.1
1.1
3.20
2.26
iu/ml
—
6
44
327
1762
1.06
0.41
1.1
1.1
1.12
1.88
iu/ml
—
8
23
0
15
0.00
0.41
0.0
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—
—
—
0
0
0
15
0.00
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0.0
1.3
—
—
—
0
0
0
15
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—
—
—
0
0
0
15
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1.3
—
—
—
0
0
0
16
0.00
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—
—
—
0
0
0
16
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—
—
—
0
0
0
16
0.00
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—
—
—
0
0
0
16
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—
—
—
0
0
0
16
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1.3
—
—
—
0
0
0
17
0.00
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0.0
1.0
—
—
—
0
0
290
2065
0.95
0.40
1.1
1.1
1.03
2.05
iu/ml
2.69
11
49
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
7
103
0.68
0.39
1.1
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—
—
—
0
0
8
61
1.31
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1.0
1.3
—
—
—
0
0
7
104
0.67
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1.3
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—
—
—
0
0
5
35
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—
—
—
0
0
0
19
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1.2
—
—
—
0
0
165
1537
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1.1
0.53
2.29
iu/ml
—
6
31
116
1052
1.09
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1.2
1.1
0.72
2.37
iu/ml
—
5
42
101
759
1.10
0.38
1.1
1.2
—
1.72
—
0
7
30
252
1.19
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1.1
1.1
—
3.21
—
0
5
9
68
1.33
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1.3
1.1
—
—
—
0
0
5
37
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1.0
1.2
—
—
—
0
0
31
262
1.19
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1.1
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—
3.16
—
0
5
6
42
1.43
0.35
1.0
1.2
—
—
—
0
0
14
108
1.30
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1.1
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—
—
—
0
0
59
659
0.89
0.35
1.1
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—
1.54
—
0
7
250
1786
1.05
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1.1
1.1
2.85
1.75
iu/ml
—
10
62
6
45
1.34
0.34
1.2
1.0
—
—
—
0
0
130
1140
1.08
0.33
1.1
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—
2.22
—
0
11
411
3729
1.04
0.33
1.2
1.1
0.90
2.07
iu/ml
3.84
13
70
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
50
546
0.89
0.32
1.1
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—
1.69
—
0
7
85
781
1.09
0.31
1.2
1.1
—
2.40
—
0
7
7
54
1.30
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1.6
1.0
—
—
—
0
0
7
53
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1.3
—
—
—
0
0
10
75
1.34
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—
—
—
0
0
178
1502
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1.1
1.92
2.14
iu/ml
—
7
47
7
55
1.28
0.30
1.3
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—
—
—
0
0
214
1461
1.05
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1.1
2.56
2.05
iu/ml
—
9
54
10
75
1.32
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1.2
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—
—
—
0
0
11
85
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—
—
—
0
0
46
509
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—
2.60
—
0
6
18
148
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—
—
—
0
0
543
3177
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2.00
1.85
iu/ml
0.09
14
69
153
1578
0.95
0.27
1.1
1.1
0.67
2.09
iu/ml
—
6
45
276
1829
1.04
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1.1
1.1
2.62
2.02
iu/ml
—
9
57
75
693
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0.26
1.3
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—
3.11
—
0
6
9
73
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1.0
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—
—
—
0
0
502
3180
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2.39
1.84
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0.37
16
70
11
88
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0.22
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—
—
—
0
0
7
92
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—
—
0
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5
40
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—
—
0
0
43
472
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3.16
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0
5
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—
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—
—
0
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5
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—
—
—
0
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5
42
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—
0
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—
—
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—
—
—
0
0
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11
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—
—
0
0
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11
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—
—
0
0
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11
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—
—
0
0
0
11
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—
—
0
0
0
11
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—
—
—
0
0
0
10
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—
—
—
0
0
0
12
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—
0
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12
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—
—
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—
—
0
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0
12
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—
—
—
0
0
0
12
0.00
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—
—
—
0
0
0
12
0.00
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0.0
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—
—
—
0
0
62
575
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1.1
1.1
—
1.98
—
0
8
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
0
13
0.00
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1.3
—
—
—
0
0
0
13
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1.5
—
—
—
0
0
0
13
0.00
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—
—
—
0
0
0
13
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—
—
—
0
0
0
13
0.00
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—
—
—
0
0
0
13
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—
—
—
0
0
0
13
0.00
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—
—
—
0
0
41
373
1.10
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1.0
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—
2.72
—
0
12
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
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1.4
—
—
—
0
0
0
14
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—
—
—
0
0
0
14
0.00
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—
—
—
0
0
6
50
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1.2
1.2
—
—
—
0
0
337
2200
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1.41
2.14
iu/ml
0.91
13
62
7
61
1.15
0.17
1.0
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—
—
—
0
0
5
66
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—
—
—
0
0
5
66
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—
—
—
0
0
320
3113
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0.85
2.05
iu/ml
—
9
53
38
410
0.92
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1.3
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—
1.47
—
0
5
8
73
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1.5
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—
—
—
0
0
6
76
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—
—
0
0
6
79
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—
—
0
0
6
79
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—
—
—
0
0
9
78
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—
—
—
0
0
9
83
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—
—
—
0
0
7
87
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—
—
—
0
0
11
93
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—
—
—
0
0
64
557
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1.1
2.14
2.09
iu/ml
—
5
25
11
92
1.18
0.14
1.1
1.1
—
—
—
0
0
58
614
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—
0.98
—
0
6
30
276
1.09
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—
2.41
—
0
5
251
2502
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1.2
1.1
2.06
2.07
iu/ml
—
8
51
207
2016
1.03
0.13
1.2
1.1
2.06
2.20
iu/ml
—
8
46
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
5
45
1.11
0.10
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—
—
—
0
0
15
135
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—
—
—
0
0
5
46
1.09
0.09
1.2
1.2
—
—
—
0
0
285
2600
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1.73
2.07
iu/ml
—
10
55
46
483
0.95
0.09
1.1
1.1
—
2.73
—
0
11
5
48
1.04
0.09
1.2
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—
—
—
0
0
35
370
0.95
0.09
1.2
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—
2.76
—
0
7
6
55
1.09
0.09
1.0
1.2
—
—
—
0
0
6
55
1.09
0.09
1.5
1.2
—
—
—
0
0
6
58
1.03
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1.0
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—
—
—
0
0
5
64
0.78
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1.4
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—
—
—
0
0
5
64
0.78
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1.0
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—
—
—
0
0
31
328
0.94
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1.1
—
2.87
—
0
5
41
391
1.05
0.08
1.0
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—
2.53
—
0
13
312
2832
0.99
0.07
1.2
1.1
1.73
1.94
iu/ml
—
10
62
71
687
1.03
0.07
1.2
1.1
—
3.31
—
0
6
6
70
0.86
0.07
1.3
1.1
—
—
—
0
0
8
74
1.03
0.07
1.3
1.1
—
—
—
0
0
44
422
1.04
0.07
1.2
1.1
—
3.16
—
0
5
34
356
0.95
0.06
1.1
1.1
—
2.89
—
0
6
12
109
1.10
0.06
1.1
1.1
—
—
—
0
0
89
910
0.98
0.05
1.1
1.1
—
2.49
—
0
15
46
475
0.97
0.05
1.1
1.1
—
1.88
—
0
5
220
2174
1.01
0.04
1.2
1.1
2.06
2.09
iu/ml
—
8
49
137
959
0.99
0.04
1.1
1.1
—
2.23
—
0
11
24
229
1.05
0.04
1.1
1.1
—
2.12
—
0
10
255
1776
1.01
0.04
1.1
1.1
—
2.21
—
0
19
296
2738
0.99
0.03
1.2
1.1
1.73
1.97
iu/ml
—
10
61
37
359
1.03
0.03
1.2
1.1
—
2.20
—
0
15
133
1174
0.99
0.03
1.1
1.1
—
2.36
—
0
14
191
1382
1.01
0.02
1.1
1.1
2.61
2.11
iu/ml
—
7
50
10
107
0.93
0.02
1.4
1.1
—
—
—
0
0
139
1396
1.00
0.00
1.1
1.1
2.47
2.04
iu/ml
—
7
39
195
1349
1.00
0.00
1.1
1.1
3.98
1.50
iu/ml
—
6
41
13
131
0.99
0.00
1.1
1.2
—
—
—
0
0
64
631
1.00
0.00
1.1
1.1
—
2.65
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
9
89
1.01
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
6
69
0.87
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.0
1.1
—
—
—
0
0
5
56
0.89
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
5
56
0.89
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
6
66
0.91
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
52
0.96
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0