alcohol withdrawal delirium: An acute organic mental disorder induced by cessation or reduction in chronic alcohol consumption. Clinical characteristics include confusion; delusions; vivid hallucinations; tremor; agitation; insomnia; and signs of autonomic hyperactivity (e.g., elevated blood pressure and heart rate, dilated pupils, and diaphoresis). This condition may occasionally be fatal. It was formerly called delirium tremens. (From Adams et al., Principles of Neurology, 6th ed, p1175)
Mental and behavioural disorders due to use of volatile solvents
DOID EFO Endpoint Browser PheWeb
F5_SOLVENT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
120 |
4. Check minimum number of eventsNone |
120 |
5. Include endpointsNone |
120 |
6. Filter based on genotype QC (FinnGen only) |
101 |
Control definitions (FinnGen only)
- Control exclude
- F5_SUBSNOALCO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F10-F19
- Name in latin
- Perturbationes mentis et modi se gerendi ex usu solventium volatilium
Similar endpoints
↥List of similar endpoints to
Mental and behavioural disorders due to use of volatile solvents
based on the number of shared cases.
Similar with more cases:
- Substance use, excluding alcohol
- Substance abuse, excluding more controls
- Substance abuse
- Mental and behavioural disorders due to psychoactive substance use
- Any mental disorder
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1225 | 317 | 902 |
| Only index persons | 1060 | 291 | 769 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.01 | 0.03 |
| Only index persons | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 28.99 | 26.78 | 29.71 |
| Only index persons | 28.18 | 26.16 | 28.94 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 101 | 36 | 65 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 28.52 | 26.70 | 29.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 111
- Matched controls
- 1110
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T36
ICD-10 Finland
Poisoning by systemic antibiotics
44.1
76.3
51
21
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
39.1
62.4
42
17
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
24.1
60.9
54
42
B18.2
ICD-10 Finland
Chronic viral hepatitis C
401.1
50.5
47
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
16.2
44.7
48
50
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
15.2
42.4
47
51
N05AH03
ATC
olanzapine; systemic
14.6
41.3
47
53
P19
ICPC
Drug abuse
+∞
41.2
37
*
P15
ICPC
Chronic alcohol abuse
20.8
41.0
35
24
N05AH04
ATC
quetiapine; oral
10.6
36.0
69
149
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
+∞
35.3
32
*
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
+∞
35.3
32
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
13.5
32.5
36
38
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
30.6
28
*
F18.1
ICD-10 Finland
Mental and behavioural disorders due to use of volatile solvents, harmful use
+∞
29.5
27
*
Z72.2
ICD-10 Finland
Drug use
+∞
28.3
26
*
N05BA01
ATC
diazepam; systemic, rectal
9.8
28.3
42
65
N07BB01
ATC
disulfiram; oral
13.1
28.1
31
32
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
+∞
24.9
23
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
+∞
23.8
22
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
+∞
23.8
22
*
N05AX08
ATC
risperidone; systemic
9.2
23.2
34
51
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
256.1
21.4
21
*
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
+∞
20.4
19
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
+∞
20.4
19
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
6.6
20.2
44
100
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
+∞
19.3
18
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
20.3
18.7
28
18
N05BA12
ATC
alprazolam; oral
8.2
18.6
29
46
F18.20
ICD-10 Finland
Dependence relationship caused by volatile solvents currently independent
+∞
18.2
17
*
F15.5
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, psychotic disorder
+∞
18.2
17
*
P18
ICPC
Medication abuse
212.5
18.1
18
*
N05BA04
ATC
oxazepam; oral
5.4
17.4
53
160
R56.8
ICD-10 Finland
Other and unspecified convulsions
8.2
16.5
25
38
Z2446
NOMESCO Finland
Social worker
7.8
16.3
26
42
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
+∞
16.0
15
*
3046A
ICD-9 Finland
Drug dependence, Other specified drug dependence
+∞
16.0
15
*
N06AX11
ATC
mirtazapine; oral
5.0
16.0
65
245
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
8.3
15.5
23
34
P16
ICPC
Acute alcohol abuse
22.5
15.4
22
12
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
19.0
15.2
23
15
T40.6
ICD-10 Finland
Poisoning: Other and unspecified narcotics
+∞
14.9
14
*
F19.9
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, unspecified mental and behavioural disorder
+∞
14.9
14
*
F13.1
ICD-10 Finland
Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
+∞
14.9
14
*
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
16.7
14.5
23
17
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
28.2
14.4
19
8
K04.5
ICD-10 Finland
Chronic apical periodontitis
4.7
14.3
50
165
N05AH02
ATC
clozapine; systemic
15.8
14.2
23
18
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
7.4
14.0
23
38
F19.00
ICD-10 Finland
Intoxication caused by several drugs in combination or by other psychoactive substances uncomplicated
+∞
13.8
13
*
F18.29
ICD-10 Finland
Dependence caused by volatile solvents UNS
+∞
13.8
13
*
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
+∞
13.8
13
*
F12.1
ICD-10 Finland
Mental and behavioural disorders due to use of cannabinoids, harmful use
+∞
13.8
13
*
F11.21
ICD-10 Finland
Addiction-indiced dependence caused by opiates currently independent but staying in controlling environment
+∞
13.8
13
*
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
158.6
13.8
14
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
5.0
13.7
39
109
F10.09
ICD-10 Finland
Alcohol intoxication UNS
16.9
13.4
21
15
F10.24
ICD-10 Finland
Alcohol depence active use
26.5
13.4
18
8
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.3
13.2
33
82
Z3231
NOMESCO Finland
Registered nurse
4.4
13.0
49
169
F10.25
ICD-10 Finland
Alcohol dependence continuous use
17.1
12.9
20
14
F10.20
ICD-10 Finland
Alcohol dependence currently independent
17.1
12.9
20
14
F19.26
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances periodic addiction
+∞
12.7
12
*
N03AE01
ATC
clonazepam; systemic
11.0
12.6
24
27
N05AD01
ATC
haloperidol; systemic
24.7
12.4
17
8
ZY010
NOMESCO Finland
Hospital outpatient
7.0
12.3
21
36
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.3
12.2
29
69
N06AB04
ATC
citalopram; systemic
4.6
12.0
37
109
A46
ICD-10 Finland
Erysipelas
5.1
11.9
30
75
N05AA02
ATC
levomepromazine; systemic
11.1
11.7
22
24
T40.9
ICD-10 Finland
Poisoning: Other and unspecified psychodysleptics [hallucinogens]
+∞
11.7
11
*
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
+∞
11.7
11
*
SPAT1275
SPAT
Drug rehabilitation and replacement therapy of opioid-dependent person
+∞
11.7
11
*
F18.00
ICD-10 Finland
Intoxication caused by volatile solvents uncomplicated
+∞
11.7
11
*
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
28.6
11.5
15
6
F20.9
ICD-10 Finland
Schizophrenia, unspecified
14.1
11.4
19
16
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
31.7
11.0
14
5
T65.9
ICD-10 Finland
Toxic effect: Toxic effect of unspecified substance
66.6
10.9
12
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.5
10.8
22
28
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.4
10.6
24
54
F19.59
ICD-10 Finland
Psychotic disorder caused by several drugs in combination and by other psychoactive substances UNS
+∞
10.6
10
*
F13.24
ICD-10 Finland
Addiction relationship caused by sedative and hypnotic active addiction
+∞
10.6
10
*
F18.9
ICD-10 Finland
Mental and behavioural disorders due to use of volatile solvents, unspecified mental and behavioural disorder
+∞
10.6
10
*
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
+∞
10.6
10
*
F61.0
ICD-10 Finland
Mixed personality disorders
26.4
10.5
14
6
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
26.4
10.5
14
6
AA1AD
NOMESCO Finland
CT of head and brain
4.0
10.4
40
137
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
10.3
10.3
20
23
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
8.6
10.1
22
31
N06AX16
ATC
venlafaxine; oral
4.1
10.1
35
111
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
22.6
10.1
14
7
N05CD07
ATC
temazepam; oral
5.9
10.0
20
40
L17
ICPC
Foot/toe symptom/complaint
3.7
10.0
46
178
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
11.7
10.0
18
18
N05BA02
ATC
chlordiazepoxide; systemic
60.4
9.8
11
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
8.7
9.8
21
29
W19
ICD-10 Finland
Unspecified fall
5.7
9.7
20
41
T74.1
ICD-10 Finland
Physical abuse
14.1
9.7
16
13
F99
ICD-10 Finland
Mental disorder, not otherwise specified
19.8
9.7
14
8
SPAT1265
SPAT
Breathalyser
33.3
9.6
12
*
F60.2
ICD-10 Finland
Dissocial personality disorder
108.9
9.6
10
*
F15.3
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, withdrawal state
+∞
9.5
9
*
IFC01, ,
SPAT
+∞
9.5
9
*
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
+∞
9.5
9
*
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
10.5
9.5
18
20
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
8.8
9.4
20
27
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
13.1
9.4
16
14
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.5
9.3
26
70
N05CF01
ATC
zopiclone; oral
3.6
9.2
42
160
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
40.3
9.2
11
*
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
14.2
9.2
15
12
F20.39
ICD-10 Finland
Undifferentiated schizophrenia UNS
26.6
9.1
12
5
C07AA05
ATC
propranolol; systemic
3.6
9.1
40
149
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
8.2
9.1
20
29
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
7.6
9.0
21
33
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.7
8.7
35
122
EBA05
NOMESCO Finland
Complicated extraction of tooth
3.4
8.7
43
172
N05AF03
ATC
chlorprothixene; systemic
14.3
8.6
14
11
F19.09
ICD-10 Finland
Intoxication caused by several drugs in combination and by other psychoactive substances UNS
+∞
8.4
8
*
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
+∞
8.4
8
*
T52.9
ICD-10 Finland
Toxic effect: Organic solvent, unspecified
+∞
8.4
8
*
X57
ICD-10 Finland
Unspecified privation
10.2
8.4
16
18
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
3.2
8.2
71
393
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
8.0
8.2
18
26
N03AG01
ATC
valproic acid; systemic, rectal
6.9
8.2
20
34
X59
ICD-10 Finland
Exposure to unspecified factor
3.3
7.8
39
156
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
20.1
7.8
11
6
OAB43, ,
SPAT
0.2
7.7
14
446
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
14.8
7.6
12
9
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
10.5
7.5
14
15
Z03
ICPC
Housing/neighbourhood problem
85.6
7.5
8
*
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
85.6
7.5
8
*
N06AX12
ATC
bupropion; oral
4.1
7.5
23
66
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
6.9
7.5
18
30
F15.0
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, acute intoxication
+∞
7.4
7
*
F11.30
ICD-10 Finland
Withdrawal symptoms caused by opiates uncomplicated
+∞
7.4
7
*
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.2
7.3
17
27
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
21.8
7.3
10
5
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
32.3
7.3
9
*
S06.0
ICD-10 Finland
Concussion
3.7
7.2
26
84
N06BA04
ATC
methylphenidate; oral
4.8
7.0
17
40
P29
ICPC
Psychological sympt/compl other
3.7
7.0
25
80
KMAK, ,
NOMESCO Finland
3.1
6.9
78
484
Y07
ICD-10 Finland
Other maltreatment
24.2
6.8
9
*
F10.0
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Acute intoxication
24.2
6.8
9
*
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
7.7
6.8
15
22
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
9.6
6.8
13
15
ZY000
NOMESCO Finland
Hospital inpatient
11.0
6.7
12
12
SGA02
NOMESCO Finland
Opening and preparing the root canals
3.6
6.6
25
83
IGV01
NOMESCO Finland
Psychiatric network contact
15.5
6.5
10
7
EBA00
NOMESCO Finland
Extraction of tooth
2.8
6.5
57
306
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
73.9
6.5
7
*
X99.9
ICD-10 Finland
Assault by sharp object by unknown person
73.9
6.5
7
*
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
73.9
6.5
7
*
F92.0
ICD-10 Finland
Depressive conduct disorder
73.9
6.5
7
*
SPAT1247
SPAT
Outpatient detoxication and monitoring
73.9
6.5
7
*
N05AX12
ATC
aripiprazole; systemic
4.5
6.4
17
43
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
6.4
42
194
K04.7
ICD-10 Finland
Periapical abscess without sinus
4.6
6.3
16
39
XF400
NOMESCO Finland
ECG with 12 standard connections
3.7
6.3
23
74
SPAT1272
SPAT
Drug screening
28.5
6.3
8
*
F11.9
ICD-10 Finland
Mental and behavioural disorders due to use of opioids, unspecified mental and behavioural disorder
+∞
6.3
6
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
+∞
6.3
6
*
F12.29
ICD-10 Finland
Addiction caused by cannabis UNS
+∞
6.3
6
*
B17.1
ICD-10 Finland
Acute hepatitis C
+∞
6.3
6
*
D72
ICPC
Viral hepatitis
+∞
6.3
6
*
F18.09
ICD-10 Finland
Intoxication caused by volatile solvents UNS
+∞
6.3
6
*
F12.24
ICD-10 Finland
Addiction caused by cannabis active addiction
+∞
6.3
6
*
P72
ICPC
Schizophrenia
7.5
6.3
14
21
WX290
NOMESCO Finland
Other blockage of nerve
2.9
6.2
78
500
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.0
6.1
16
30
ZXE00
NOMESCO Finland
One hour or less
2.7
6.0
46
228
F20
ICD-10 Finland
Schizophrenia
16.1
6.0
9
6
K04.0
ICD-10 Finland
Pulpitis
3.6
6.0
22
71
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
8
65.41
32.02
2.6
1.1
—
—
—
0
0
39
80
6.97
19.82
2.8
1.5
0.35
0.39
mg/l
0.13
26
33
56
186
5.06
16.22
4.6
1.9
1.65
1.45
%
1.46
51
177
23
15
18.97
15.21
3.6
1.1
—
—
—
0
0
31
69
5.85
14.11
6.2
2.7
—
—
—
0
0
27
54
6.29
13.71
1.9
1.4
—
—
—
0
0
23
39
7.18
13.69
13.7
7.7
1.52
1.46
%
0.07
23
39
23
39
7.18
13.69
13.7
7.7
0.63
0.68
%
0.29
23
39
21
16
15.87
13.08
35.5
15.8
1388.38
1223.44
nmol/l
0.29
21
16
33
97
4.42
10.61
12.8
6.0
105.24
104.20
mmol/l
0.68
33
97
53
222
3.66
10.25
6.6
2.9
1.02
1.02
kg/l
1.57
33
142
22
31
8.57
10.13
13.9
8.3
24.41
23.44
mmol/l
0.47
22
31
67
334
3.54
9.72
9.0
5.8
1.19
1.21
mmol/l
1.30
62
293
83
480
3.89
9.40
10.4
4.0
6.81
6.48
mmol/l
0.49
78
443
64
321
3.35
8.99
5.0
4.8
35.28
38.08
g/l
2.71
58
311
84
506
3.71
8.57
26.3
10.0
4.61
4.06
e9/l
1.01
76
453
32
121
3.31
6.91
2.5
2.5
6.44
1.02
e6/l
—
9
53
46
223
2.81
6.37
3.0
2.6
0.44
0.23
e6/l
0.46
27
163
39
177
2.86
6.07
1.6
1.6
20.19
20.05
nmol/l
0.02
39
160
53
292
2.56
5.53
1.8
1.8
104.69
97.36
pmol/l
0.43
34
162
31
135
2.80
5.12
2.5
2.4
2.60
0.65
e6/l
—
7
67
24
92
3.05
4.96
5.5
6.3
0.91
0.97
mmol/l
0.65
24
86
14
39
3.96
3.87
5.0
2.6
0.59
0.71
%
0.73
14
39
13
34
4.19
3.84
1.6
1.2
—
—
—
0
0
14
40
3.85
3.77
5.0
2.5
1.97
1.71
%
0.22
14
40
42
240
2.21
3.75
3.3
2.2
—
—
—
0
0
34
180
2.28
3.63
1.8
1.9
3.77
2.62
mg/l
0.81
29
158
41
261
1.91
2.58
3.8
2.4
—
—
—
0
0
25
133
2.14
2.58
3.0
2.5
—
—
—
0
0
101
873
2.74
2.52
20.1
9.7
102.89
96.07
ml/min/173m2
2.52
94
794
10
36
2.95
2.20
2.0
1.7
—
—
—
0
0
6
14
4.46
2.18
1.3
1.0
—
—
—
0
0
6
14
4.46
2.18
1.3
1.0
—
—
—
0
0
19
97
2.16
2.16
2.1
1.6
—
—
—
0
0
14
63
2.40
2.11
3.2
2.5
3195.95
263.62
u/l
—
6
24
23
129
1.99
2.05
2.1
1.9
—
—
—
0
0
19
100
2.09
2.00
1.9
1.6
—
—
—
0
0
21
115
2.02
2.00
2.7
2.3
—
—
—
0
0
7
21
3.48
2.00
1.4
1.2
—
—
—
0
0
26
154
1.90
1.99
2.4
3.0
62.56
191.39
ng/l
0.56
16
98
62
479
1.67
1.87
3.8
3.2
0.00
0.00
estimate
-0.00
15
93
61
472
1.65
1.81
3.8
3.0
0.00
0.00
estimate
-0.00
15
103
6
18
3.46
1.77
6.8
3.2
30.07
9.33
u/ml
—
6
18
5
13
3.97
1.73
1.2
1.0
—
—
—
0
0
29
187
1.75
1.68
3.0
1.8
—
—
—
0
0
6
19
3.28
1.68
1.2
1.2
—
—
—
0
0
61
479
1.61
1.65
3.9
3.1
0.00
0.00
estimate
-0.00
15
98
19
108
1.92
1.63
1.6
2.3
29.39
30.17
s
0.27
19
108
6
21
2.96
1.52
2.2
3.0
—
—
—
0
0
40
290
1.59
1.48
3.0
2.7
48.74
24.62
ng/l
0.27
23
158
5
17
3.03
1.37
1.4
1.1
—
—
—
0
0
7
36
2.01
0.99
5.7
3.3
58.57
57.20
%
—
7
36
6
29
2.13
0.91
1.2
2.2
3.60
3.41
g/l
—
6
29
6
30
2.06
0.88
1.2
2.5
167.33
158.47
%
—
6
30
12
73
1.72
0.85
8.2
7.4
—
—
—
0
0
33
259
1.39
0.78
4.0
2.9
0.00
0.01
estimate
0.50
15
98
47
393
1.34
0.75
3.1
2.3
—
—
estimate
—
0
0
28
222
1.35
0.62
1.3
1.7
0.92
1.25
mg/l
0.31
17
166
0
20
0.00
0.61
0.0
1.7
—
203.22
—
0
20
15
204
0.69
0.60
3.7
2.8
7.87
20.12
%
—
6
62
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
0
23
0.00
0.59
0.0
1.2
—
—
—
0
0
0
23
0.00
0.59
0.0
1.3
—
4.77
—
0
13
0
23
0.00
0.59
0.0
1.3
—
8.80
—
0
10
34
287
1.27
0.48
1.7
1.6
—
—
—
0
0
8
56
1.46
0.44
1.5
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
0.00
—
0
15
0
15
0.00
0.41
0.0
3.6
—
0.00
—
0
15
0
16
0.00
0.41
0.0
3.4
—
10.36
—
0
16
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
3.3
—
0.00
—
0
18
0
19
0.00
0.39
0.0
3.2
—
3.58
—
0
19
0
19
0.00
0.39
0.0
3.2
—
2.80
—
0
19
0
19
0.00
0.39
0.0
3.2
—
0.82
—
0
19
0
19
0.00
0.39
0.0
3.2
—
6.77
—
0
19
0
19
0.00
0.39
0.0
3.2
—
4.95
—
0
19
7
54
1.32
0.31
1.0
1.4
—
—
—
0
0
25
288
0.83
0.30
3.4
2.2
0.00
0.00
estimate
-0.00
11
81
41
372
1.16
0.27
3.4
2.7
0.00
0.01
estimate
0.49
12
86
5
37
1.37
0.24
1.0
1.9
88.80
96.95
%
—
5
37
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1308.50
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
11.98
—
0
6
0
14
0.00
0.20
0.0
1.8
—
7.26
—
0
14
0
14
0.00
0.20
0.0
4.3
—
23.63
—
0
14
0
14
0.00
0.20
0.0
1.7
—
1.09
—
0
8
8
70
1.15
0.17
1.5
2.0
165.12
241.51
pmol/l
—
8
65
13
147
0.87
0.12
1.4
1.6
—
—
—
0
0
78
797
0.93
0.09
3.9
3.7
—
—
—
0
0
16
166
0.96
0.00
2.6
2.6
12.66
15.49
nmol/l
0.70
11
161
27
264
1.03
0.00
2.5
3.0
1.10
1.41
ug/l
0.56
21
246
21
205
1.03
0.00
4.0
4.4
4.15
8.75
mg/mmol
0.68
15
142
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
15.54
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
186.87
—
0
8
0
7
0.00
-0.00
0.0
2.6
—
50.00
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
11.00
—
0
9
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
90
1.00
-0.00
1.4
1.8
264.33
374.29
nmol/l
—
9
85
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
6.30
—
0
6
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.29
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
106.48
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint F5_SOLVENT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_SOLVENT | 5.861 [3.8, 9.04] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 151 out of 599 males with F5_SOLVENT died.
Mortality risk
Mortality risk for people of age
years, who have F5_SOLVENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 1.15% |
| 5 | No data | 6.035% |
| 10 | No data | 15.889% |
| 15 | No data | 27.945% |
| 20 | No data | 43.88% |
Relationships between endpoints
↥Index endpoint: F5_SOLVENT – Mental and behavioural disorders due to use of volatile solvents
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data