psoriatic arthritis: Joint inflammation associated with psoriasis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
533 |
4. Check minimum number of eventsNone |
533 |
5. Include endpointsNone |
533 |
6. Filter based on genotype QC (FinnGen only) |
487 |
Control definitions (FinnGen only)
- Control exclude
- PSOR_ENTE_ARTHR
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Arthropathy in ulcerative colitis
based on the number of shared cases.
Similar with more cases:
- Enteropathic arthropathies
- Psoriatic and enteropathic arthropathies
- Polyarthropathies
- Finngen Rheumatological endpoints
- Used for control exclusion in common control thyroid runs
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1853 | 1058 | 791 |
| Only index persons | 1802 | 1037 | 765 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 45.60 | 44.83 | 46.65 |
| Only index persons | 45.25 | 44.58 | 46.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 487 | 315 | 172 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.08 |
| Median age at first event (years) | 47.13 | 45.24 | 50.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 505
- Matched controls
- 5050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A07EA06
ATC
budesonide; oral, local oral
49.9
307.7
247
95
A07EC02
ATC
mesalazine; oral, rectal
229.8
307.7
441
147
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
361.5
307.7
455
124
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
4503599627370496.0
307.7
462
*
A07EC01
ATC
sulfasalazine; oral, rectal
63.3
307.7
355
182
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
192.2
307.7
378
77
L04AX01
ATC
azathioprine; systemic
55.5
307.7
263
97
K51.5
ICD-10 Finland
Left sided colitis
150.5
307.7
338
67
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
110.1
307.7
223
36
A07EA02
ATC
hydrocortisone; rectal
91.3
307.7
222
43
K51.8
ICD-10 Finland
Other ulcerative colitis
54.2
273.8
163
44
UJF32
NOMESCO Finland
Coloscopy
23.3
262.6
403
731
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
86.8
259.5
139
22
L04AX03
ATC
methotrexate; systemic
18.9
242.7
250
249
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
74.1
240.1
132
24
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
15.3
204.5
236
274
K51
ICD-10 Finland
Ulcerative colitis
59.3
201.0
115
25
UJF30
NOMESCO Finland
Ileoscopy through colon
14.9
199.2
233
275
L04AB04
ATC
adalimumab; parenteral
36.1
197.4
130
48
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
71.6
187.4
103
18
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
55.7
171.5
99
22
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
15.8
171.0
174
163
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.5
161.4
173
175
L01BB02
ATC
mercaptopurine; oral
48.2
147.9
88
22
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
138.0
126
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
73.2
137.5
75
12
H02AB06
ATC
prednisolone; systemic
17.1
130.7
454
1727
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
20.9
124.5
100
59
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
12.2
122.8
142
157
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
19.9
121.5
100
62
K50.9
ICD-10 Finland
Crohn disease, unspecified
29.6
113.8
78
31
L01BA01
ATC
methotrexate; systemic
20.8
112.8
90
52
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.3
109.6
319
966
L04AB06
ATC
golimumab; parenteral
61.8
106.9
60
11
H02AB07
ATC
prednisone; oral
7.8
102.9
187
354
K50.1
ICD-10 Finland
Crohn disease of large intestine
31.3
101.6
68
25
K50.8
ICD-10 Finland
Other Crohn disease
24.0
90.7
67
32
M13.9
ICD-10 Finland
Arthritis, unspecified
9.0
87.6
125
178
L88
ICPC
Rheumatoid/seropositive arthritis
12.0
74.0
80
78
J01MA02
ATC
ciprofloxacin; systemic
5.0
70.3
312
1233
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
10.6
68.8
81
89
D94
ICPC
Chronic enteritis/ulcerative colitis
96.2
68.1
74
9
ZX120
NOMESCO Finland
Intravenous
6.6
65.3
124
237
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
12.9
64.1
65
57
M45
ICD-10 Finland
Ankylosing spondylitis
14.1
62.6
60
48
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
235.0
61.6
62
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
23.4
53.0
39
18
P01BA02
ATC
hydroxychloroquine; oral
6.1
52.5
104
205
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
526.3
49.2
48
*
A07EA01
ATC
prednisolone; oral, rectal
75.3
48.2
54
8
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
13.6
47.6
46
37
L04AD01
ATC
ciclosporin; systemic
14.2
45.7
43
33
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
105.9
44.6
48
5
TPH04
NOMESCO Finland
Cathetrisation of vein
3.9
44.1
186
663
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.6
42.9
218
876
K50.0
ICD-10 Finland
Crohn disease of small intestine
12.6
42.6
43
37
P01AB01
ATC
metronidazole; oral, rectal
3.4
40.0
310
1599
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.6
39.7
45
46
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
14.8
39.4
36
26
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
38.2
305
1587
H02AB09
ATC
hydrocortisone; systemic
9.5
35.9
44
50
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
14.1
35.1
33
25
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
34.8
33
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.3
34.5
102
278
N02AX02
ATC
tramadol; systemic, rectal
3.1
33.6
288
1525
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
181.9
33.1
34
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.8
31.9
46
64
L04AC05
ATC
ustekinumab; parenteral
42.1
31.7
39
10
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
64.4
31.5
36
6
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
117.5
31.0
33
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
30.0
159
634
WX302
NOMESCO Finland
Thoracal epidural anesthesy
6.1
29.9
55
99
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.2
29.6
37
43
WX002
NOMESCO Finland
Sedation and analgesia
3.4
29.5
136
498
4AA12, ,
NOMESCO Finland
60.6
29.5
34
6
M01AH01
ATC
celecoxib; oral
3.4
29.3
131
471
NH3EA
NOMESCO Finland
Feet X-ray examination with load
11.0
29.2
32
31
L04AB01
ATC
etanercept; parenteral
11.7
28.7
30
27
A06AC01
ATC
ispaghula (psylla seeds); oral
2.9
28.0
182
810
M07.3
ICD-10 Finland
Other psoriatic arthropathies
297.2
28.0
28
*
UJF92
NOMESCO Finland
Capsular endoscopy
9.5
27.1
33
37
L40.5
ICD-10 Finland
Arthropathic psoriasis
63.6
26.3
30
5
M25.5
ICD-10 Finland
Pain in joint
2.7
26.2
252
1364
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.8
25.8
89
268
UJG02
NOMESCO Finland
Proctoscopy
9.9
25.5
30
32
L04AB02
ATC
infliximab; parenteral
25.9
24.7
34
14
WVA20
NOMESCO Finland
Medicine administration
7.0
24.6
39
60
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
36.6
24.6
31
9
A02BC02
ATC
pantoprazole; systemic
3.1
24.5
396
2743
L04AA13
ATC
[U] leflunomide
8.5
24.1
32
40
A07DA03
ATC
loperamide; oral
6.4
23.8
41
69
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
56.9
23.3
27
5
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
23.2
106
382
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
218.6
20.7
21
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.4
20.1
34
56
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.0
20.1
61
167
253, ,
Kela drug reimbursment
37.5
20.0
25
7
3042, ,
Kela drug reimbursment
37.5
20.0
25
7
4AB02, ,
NOMESCO Finland
41.9
19.7
24
6
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.5
19.6
51
124
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
7.9
19.3
27
36
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
18.9
149
712
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.5
18.8
48
115
L04AA01
ATC
[U] ciclosporin
15.9
18.7
30
20
H02AB04
ATC
methylprednisolone; systemic
2.9
18.6
103
411
C10AC01
ATC
colestyramine; oral
6.0
18.3
33
58
L40.0
ICD-10 Finland
Psoriasis vulgaris
5.0
18.1
40
85
JFH11
NOMESCO Finland
Laparoscopic colectomy
186.3
17.6
18
*
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
19.5
17.5
26
14
1370
FHL
Colonoscopy, whole colon
43.7
17.4
21
5
L04AF03
ATC
upadacitinib; oral
32.8
17.2
22
7
M05BA04
ATC
alendronic acid; oral
4.3
17.0
46
115
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
17.0
227
1353
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
16.8
71
242
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
16.5
265
1694
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
16.3
232
1411
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
16.2
73
258
A02BC01
ATC
omeprazole; systemic
2.3
16.1
159
832
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
16.1
80
299
256, ,
Kela drug reimbursment
62.1
15.9
18
*
Z93.2
ICD-10 Finland
Ileostomy status
34.6
15.8
20
6
A07EC03
ATC
olsalazine; oral
164.9
15.6
16
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
15.5
86
342
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
15.4
63
210
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
6.3
15.3
26
43
JHA00
NOMESCO Finland
Anal or perianal incision
6.8
15.0
24
37
K83.0
ICD-10 Finland
Cholangitis
13.0
15.0
26
21
K61.0
ICD-10 Finland
Anal abscess
6.4
14.8
25
41
L04AG05
ATC
vedolizumab; parenteral
25.9
14.8
20
8
N03AX16
ATC
[U] pregabalin
2.3
14.7
142
732
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.6
14.7
52
158
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
14.7
14
*
K92.1
ICD-10 Finland
Melaena
4.4
14.4
37
89
L04AA33
ATC
[U] vedolizumab
43.8
14.2
17
*
WZA10
NOMESCO Finland
Extensive medical or dental certificate
6.9
14.1
22
33
N02BE01
ATC
paracetamol; systemic, rectal
4.1
14.0
476
4043
NG1DA
NOMESCO Finland
X-ray of knees
6.7
13.8
22
34
K50
ICD-10 Finland
Crohn disease [regional enteritis]
77.3
13.6
15
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.2
13.6
37
93
JFF10
NOMESCO Finland
Loop enterostomy
26.6
13.4
18
7
A02BC05
ATC
esomeprazole; systemic
2.0
13.2
231
1486
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
13.2
69
265
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
11.4
13.1
24
22
J01MA12
ATC
levofloxacin; systemic
2.4
13.1
102
476
JAH00
NOMESCO Finland
Laparotomy
5.2
13.0
27
54
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.8
13.0
24
43
M075, K509,
ICD-10 Finland
+∞
12.5
12
*
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
20.7
12.5
18
9
M01AH02
ATC
rofecoxib; oral
2.7
12.5
71
284
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
12.5
196
1208
J01DB01
ATC
cefalexin; oral
2.7
12.5
445
3697
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
38.6
12.3
15
*
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
12.8
12.2
21
17
K56.7
ICD-10 Finland
Ileus, unspecified
10.4
12.1
23
23
D07AC01
ATC
betamethasone; topical
2.0
12.1
197
1228
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
13.8
12.0
20
15
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
11.8
76
324
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
11.8
75
318
Z3231
NOMESCO Finland
Registered nurse
2.1
11.8
152
870
3029
Kela drug reimbursment
Upadacitinib
16.9
11.7
18
11
298, ,
Kela drug reimbursment
16.9
11.7
18
11
TJF80
NOMESCO Finland
Ostomy education
16.9
11.7
18
11
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
11.7
81
357
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
11.7
51
176
JFH10
NOMESCO Finland
Total colectomy and ileostomy
66.5
11.7
13
*
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
66.5
11.7
13
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
66.5
11.7
13
*
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
11.5
11.6
21
19
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
11.5
11
*
Z2221
NOMESCO Finland
Medical doctor
2.0
11.5
162
956
M13.0
ICD-10 Finland
Polyarthritis, unspecified
10.9
11.4
21
20
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.4
186
1156
WX402
NOMESCO Finland
General anaesthesia
2.1
11.3
137
765
B01AB05
ATC
enoxaparin; parenteral
2.0
11.2
166
995
D07AD01
ATC
clobetasol; topical
2.3
11.1
100
496
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
11.0
84
387
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
10.9
41
129
K60.3
ICD-10 Finland
Anal fistula
5.3
10.9
22
43
L04AB05
ATC
certolizumab pegol; parenteral
18.3
10.8
16
9
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
10.7
195
1250
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
10.7
87
413
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.5
10.6
37
111
M075, L405,
ICD-10 Finland
+∞
10.4
10
*
M075, K515,
ICD-10 Finland
+∞
10.4
10
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
10.4
52
194
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
10.4
145
849
A05AA02
ATC
ursodeoxycholic acid; oral
5.1
10.4
22
45
M01AX17
ATC
nimesulide; oral
2.1
10.3
115
619
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
4.5
10.2
25
58
TNG10
NOMESCO Finland
Puncture of knee
8.7
10.1
21
25
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
10.1
245
1713
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
10.0
209
1395
A07AA09
ATC
vancomycin; oral
12.5
9.9
17
14
3005
Kela drug reimbursment
Tofacitinib
20.5
9.8
14
7
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.6
9.8
32
92
L20
ICPC
Joint symptom/complaint NOS
3.6
9.8
33
97
M01AH05
ATC
etoricoxib; oral
1.9
9.8
354
2789
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
9.7
162
1003
R50.9
ICD-10 Finland
Fever, unspecified
2.2
9.7
94
478
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
8.6
9.6
20
24
E0000UV, ,
ATC
1.8
9.6
225
1548
R4110
NOMESCO Finland
Physiotherapy
1.9
9.6
151
918
N05CF01
ATC
zopiclone; oral
1.9
9.5
166
1042
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
101.9
9.4
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
9.4
73
338
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
9.4
9
*
Z3226
NOMESCO Finland
Physiotherapist
2.1
9.4
99
521
C05AA08
ATC
fluocortolone; rectal, topical
2.3
9.2
78
375
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
5.0
8.9
19
39
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
8.9
52
211
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
8.8
8.9
18
21
K56.0
ICD-10 Finland
Paralytic ileus
11.0
8.8
16
15
M01AC06
ATC
meloxicam; systemic, rectal
1.8
8.8
193
1295
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.8
120
693
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
14.4
8.7
14
10
3AC01, ,
NOMESCO Finland
14.4
8.7
14
10
A03CA02
ATC
clidinium and psycholeptics; oral
3.4
8.6
31
95
R03DC03
ATC
montelukast; oral
2.0
8.6
101
553
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.7
8.5
27
76
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
91.5
8.4
9
*
Z43.2
ICD-10 Finland
Attention to ileostomy
91.5
8.4
9
*
K51.4
ICD-10 Finland
Inflammatory polyps
91.5
8.4
9
*
TQW40
NOMESCO Finland
Remowal of suture of skin
2.7
8.4
45
174
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
8.4
388
3212
R05
ICD-10 Finland
Cough
1.9
8.4
121
710
D01
ICPC
Abdominal pain/cramps general
2.2
8.4
76
376
M073, K519,
ICD-10 Finland
+∞
8.4
8
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
9.7
8.3
16
17
XX9XE
NOMESCO Finland
Other ultrasound examination
9.7
8.3
16
17
A02BC03
ATC
lansoprazole; oral
1.8
8.2
143
892
N06AX11
ATC
mirtazapine; oral
1.8
8.2
187
1264
L04AA29
ATC
[U] tofacitinib
17.5
8.1
12
7
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
17.5
8.1
12
7
Z3229
NOMESCO Finland
Other healthcare associate professional
2.8
8.0
42
161
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.9
8.0
38
138
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
13.3
7.9
13
10
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
7.9
46
186
M01CB01
ATC
sodium aurothiomalate; parenteral
11.0
7.8
14
13
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
7.1
7.8
18
26
SAA02
NOMESCO Finland
Basic examination of mouth
1.8
7.8
370
3048
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
45.7
7.7
9
*
ZXE00
NOMESCO Finland
One hour or less
1.7
7.6
200
1398
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
7.6
305
2388
D05AX02
ATC
calcipotriol; topical
3.9
7.6
22
58
R4190
NOMESCO Finland
Nutritional therapy
3.1
7.6
31
103
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
9.1
7.6
15
17
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
10.2
7.6
14
14
L15
ICPC
Knee symptom/complaint
1.8
7.6
133
829
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
7.6
42
166
J05AB11
ATC
valaciclovir; oral
2.0
7.5
89
487
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
81.2
7.4
8
*
D05AX52
ATC
calcipotriol, combinations; topical
3.0
7.4
32
110
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
7.3
392
3308
M07.6
ICD-10 Finland
Other enteropathic arthropathies
+∞
7.3
7
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
7.3
7
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
7.3
61
292
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.1
7.2
31
106
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.6
7.2
43
176
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.5
7.2
25
75
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.9
7.1
21
56
A07AA02
ATC
nystatin; oral
2.9
7.1
34
124
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
7.1
218
1582
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
7.1
62
302
M03BX02
ATC
tizanidine; oral
1.7
7.1
338
2747
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
7.0
221
1613
M54.5
ICD-10 Finland
Low back pain
1.7
7.0
197
1396
JF1BD
NOMESCO Finland
Very extensive small bowel CT
14.0
6.9
11
8
J02AC01
ATC
fluconazole; systemic
1.7
6.9
221
1618
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
6.9
54
251
D06BX01
ATC
metronidazole; topical
2.1
6.8
65
327
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
11.1
6.8
12
11
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.7
6.8
21
58
M17.5
ICD-10 Finland
Other secondary gonarthrosis
5.8
6.8
18
32
G47.3
ICD-10 Finland
Sleep apnoea
1.8
6.8
126
796
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
17.0
6.8
10
6
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.8
6.7
33
122
N02BF01
ATC
gabapentin; oral
2.1
6.7
64
322
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
22.9
6.7
9
*
A07AA11
ATC
rifaximin; oral
22.9
6.7
9
*
B01AB10
ATC
tinzaparin; parenteral
2.2
6.7
61
302
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
6.7
141
923
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.7
112
686
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
8.0
6.7
14
18
WZC30
NOMESCO Finland
Teaching
1.9
6.6
89
507
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
12.5
6.6
11
9
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.3
6.6
17
41
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
6.6
192
1369
R03AC02
ATC
salbutamol; inhalant
1.6
6.5
294
2332
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
6.5
36
142
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
70.7
6.4
7
*
JFF13
NOMESCO Finland
Terminal enterostomy
70.7
6.4
7
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
14.5
6.4
10
7
M79.1
ICD-10 Finland
Myalgia
1.9
6.3
91
530
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
6.3
6
*
6410
FHL
Panprococolectomy and ileostomy
+∞
6.3
6
*
JFB00
NOMESCO Finland
Partial resection of small intestine
7.2
6.3
14
20
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.2
6.2
24
77
6419
FHL
Other measure in this category
27.0
6.2
8
*
WX290
NOMESCO Finland
Other blockage of nerve
1.6
6.2
276
2170
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.5
6.2
21
62
RD210, ,
NOMESCO Finland
5.5
6.2
17
32
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.5
6.2
37
152
R4120
NOMESCO Finland
Occupational therapy
2.4
6.2
41
177
Z50.1
ICD-10 Finland
Other physical therapy
2.9
6.2
29
105
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.9
6.1
18
48
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
4.2
6.1
16
39
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
4.2
6.1
16
39
H15.1
ICD-10 Finland
Episcleritis
5.3
6.1
17
33
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
10.2
6.1
11
11
R06.0
ICD-10 Finland
Dyspnoea
1.7
6.0
127
828
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
389
653
22.58
269.51
9.5
2.6
184.43
111.43
ug/g
3.22
377
531
207
276
12.02
159.03
2.4
1.5
—
—
—
0
0
153
150
14.20
144.71
1.8
1.5
0.03
0.05
iu/ml
0.15
34
22
65
14
53.14
112.30
2.9
4.5
48.92
35.60
au/ml
—
9
5
427
1766
10.18
103.57
10.9
5.1
36.39
36.62
g/l
0.50
419
1681
54
13
46.39
90.63
1.7
2.2
154.46
—
au/ml
—
15
0
471
2367
15.70
86.87
20.8
6.7
2.02
1.93
e9/l
0.81
461
2108
473
2402
16.30
85.84
20.9
7.1
0.20
0.18
e9/l
1.12
461
2124
476
2568
15.86
76.82
21.9
10.3
4.05
4.05
e9/l
0.02
467
2262
286
1061
4.91
69.80
4.3
2.2
2.74
2.81
mg/l
0.20
267
924
408
2025
6.28
68.05
4.8
2.6
73.88
75.01
nmol/l
0.41
401
1870
381
2018
4.62
52.13
24.6
10.6
0.00
0.00
e9/l
0.19
360
1654
491
3289
18.78
48.19
12.7
4.2
12.20
10.07
mm/h
3.78
484
3101
49
45
11.95
46.65
1.3
1.2
—
—
—
0
0
221
892
3.63
43.27
1.5
1.3
7.06
10.90
u/ml
0.39
82
364
188
692
3.73
42.24
3.0
2.5
12.87
14.32
umol/l
1.67
181
647
169
588
3.82
41.16
2.8
2.5
21.62
24.40
%
1.79
162
556
73
129
6.45
40.79
1.5
1.3
—
—
—
0
0
178
655
3.65
39.66
2.8
2.4
2.42
2.36
g/l
0.69
172
610
391
2351
3.94
38.96
5.4
3.5
0.00
0.00
estimate
-0.00
114
465
388
2330
3.87
38.54
5.3
3.5
0.00
0.00
estimate
-0.00
114
463
391
2370
3.88
38.03
5.4
3.5
0.09
0.01
estimate
0.79
108
441
91
211
5.04
37.78
1.8
1.7
8.06
6.52
iu/ml
0.20
16
50
62
101
6.86
37.40
3.0
6.0
997.89
211.57
iu/ml
—
9
14
59
103
6.35
33.20
1.7
1.3
—
—
—
0
0
212
965
3.06
32.11
1.5
1.3
34.11
28.51
iu/ml
0.15
66
297
58
103
6.23
32.06
1.5
1.2
—
—
—
0
0
361
2302
2.99
27.72
5.2
3.1
91.38
95.69
ug/l
0.27
353
2189
111
372
3.54
27.56
2.7
2.6
11.44
10.54
g/l
1.65
105
346
33
41
8.54
25.03
2.2
1.4
42.28
47.58
%
0.26
26
31
326
2033
2.70
24.99
6.7
7.6
1.22
1.21
mmol/l
0.28
291
1782
352
2293
2.77
24.50
8.0
6.8
9.81
10.82
umol/l
1.51
343
2191
48
100
5.20
22.24
1.9
1.4
7983.59
13246.58
e6/l
0.42
39
72
107
402
3.11
21.70
2.9
2.6
0.23
0.22
g/l
0.57
98
384
64
172
4.12
21.65
1.3
1.3
—
—
—
0
0
241
1371
2.45
21.36
4.4
2.8
62.12
64.04
u/l
0.13
229
1293
288
1811
2.37
19.88
6.4
7.0
1.21
1.21
mmol/l
0.01
277
1688
224
1264
2.39
19.85
5.8
3.6
0.00
0.01
estimate
0.78
109
445
202
1097
2.40
19.43
1.9
1.6
20.50
21.16
nmol/l
0.25
188
953
206
1135
2.38
19.11
3.6
2.9
0.35
0.39
e6/l
0.13
171
819
280
1778
2.29
18.37
2.4
2.0
95.60
98.36
pmol/l
0.48
184
951
266
1655
2.28
18.32
5.3
3.4
29.83
30.62
u/l
0.27
249
1571
49
122
4.34
18.27
1.2
1.3
—
—
—
0
0
279
1775
2.28
18.15
11.3
9.5
1.13
1.14
inr
0.15
242
1466
35
68
5.46
17.47
1.3
1.4
—
—
—
0
0
281
1813
2.24
17.40
5.5
3.4
0.04
0.02
estimate
0.23
101
392
225
1332
2.24
17.17
3.9
3.0
251.66
101.82
e6/l
0.39
193
1008
169
897
2.33
16.67
3.1
2.5
5.31
6.67
e6/l
0.58
162
818
53
151
3.80
16.44
1.2
1.3
14.90
12.35
u/ml
—
5
27
140
697
2.40
15.88
2.9
2.6
0.98
0.84
e6/l
0.38
94
362
96
400
2.73
15.80
2.8
2.4
56.15
152.56
u/l
0.37
87
339
42
105
4.27
15.55
3.9
2.7
1.00
2.02
index
0.96
25
63
117
546
2.49
15.24
8.8
8.1
104.63
104.34
mmol/l
0.39
117
546
40
99
4.30
15.00
1.3
1.4
316.90
245.55
u/ml
0.65
21
52
59
192
3.35
14.97
1.5
1.7
—
—
—
0
0
192
1119
2.15
14.72
2.9
2.6
312.17
330.78
umol/l
2.14
180
1004
52
161
3.49
14.25
2.1
1.4
0.22
0.24
g/l
1.18
52
156
459
3810
3.25
14.18
39.7
17.0
13.84
13.46
%
8.40
459
3770
25
43
6.06
14.12
1.3
1.2
—
—
—
0
0
26
47
5.78
13.97
1.2
1.2
56.10
54.87
u/l
0.03
21
41
53
169
3.39
13.87
2.1
1.4
1.19
1.20
g/l
0.13
53
163
185
1084
2.12
13.82
5.6
3.8
94.78
94.18
%
0.13
177
1061
28
55
5.33
13.79
1.3
1.2
—
—
—
0
0
86
365
2.63
13.54
3.0
3.7
2.42
1.70
mmol/l
1.01
73
321
25
45
5.79
13.49
1.3
1.2
—
—
—
0
0
25
45
5.79
13.49
1.3
1.2
—
—
—
0
0
34
81
4.43
13.37
1.2
1.2
—
—
—
0
0
22
36
6.34
13.03
1.5
1.2
373.33
74.00
titre
—
9
5
24
43
5.81
13.01
1.3
1.2
—
—
—
0
0
489
4271
5.57
12.97
29.7
12.7
88.85
87.33
ml/min/173m2
0.97
478
3907
44
133
3.53
12.49
1.4
1.1
—
—
—
0
0
44
134
3.50
12.35
1.4
1.1
—
—
—
0
0
25
49
5.32
12.33
1.6
1.4
—
—
—
0
0
25
49
5.32
12.33
1.3
1.2
—
—
—
0
0
330
2451
2.00
12.09
6.1
5.2
6.58
6.55
mmol/l
0.13
315
2307
24
29
8.63
11.42
2.1
1.5
42.83
42.45
%
0.01
16
20
145
826
2.06
11.31
2.7
1.7
414.76
40166641.48
pmol/l
1.19
134
722
102
508
2.26
11.20
3.6
3.0
5.19
6.41
umol/l
0.37
95
444
120
639
2.15
11.17
2.9
2.7
2.52
3.16
e6/l
0.31
73
304
21
21
10.38
11.10
1.2
1.2
19.69
16.38
u/l
0.17
16
16
170
1045
1.94
10.58
1.8
1.7
1.04
1.14
mg/l
0.26
138
808
26
61
4.44
10.42
1.8
1.4
—
—
—
0
0
26
61
4.44
10.42
1.8
1.4
—
—
—
0
0
26
61
4.44
10.42
1.8
1.4
—
—
—
0
0
169
1047
1.92
10.21
1.8
1.4
2.61
2.27
g/l
1.69
126
677
205
1357
1.86
10.06
4.6
3.0
0.00
0.01
estimate
1.08
100
377
108
579
2.10
9.77
2.1
1.7
1248.52
1221.10
nmol/l
0.10
77
449
192
1264
1.84
9.46
2.1
2.2
121.28
253.63
u/l
1.66
187
1208
490
4428
4.59
9.28
25.9
15.6
3.90
3.95
mmol/l
3.19
482
4335
24
58
4.29
9.27
1.8
1.4
—
—
—
0
0
24
59
4.22
9.08
1.7
1.4
—
—
—
0
0
24
59
4.22
9.08
1.7
1.4
—
—
—
0
0
488
4419
4.10
8.76
26.0
15.5
139.33
139.73
mmol/l
4.38
482
4338
217
1514
1.76
8.60
4.5
3.3
21.00
71.71
ng/l
0.62
137
938
53
221
2.56
8.56
2.8
3.5
24.67
24.35
mmol/l
0.31
53
221
87
463
2.06
7.93
2.9
2.2
295.37
365.87
nmol/l
2.99
81
438
19
30
6.54
7.78
1.3
1.1
—
—
—
0
0
42
164
2.70
7.73
1.6
2.2
1.59
1.42
g/l
0.62
34
143
159
1046
1.76
7.53
5.6
3.5
1.02
1.02
kg/l
1.18
119
684
162
1072
1.75
7.51
1.7
1.6
—
—
—
0
0
75
385
2.11
7.51
3.6
4.7
17.83
17.80
ug/l
0.00
54
310
19
32
6.13
7.45
1.4
1.3
6725.75
16372.76
e6/l
0.36
12
21
271
2067
1.67
7.37
3.5
2.7
—
—
estimate
—
0
0
108
641
1.87
7.14
2.3
1.9
—
—
—
0
0
30
102
3.06
7.09
1.1
1.4
—
—
—
0
0
38
148
2.70
7.04
1.5
1.9
3.01
2.96
g/l
0.10
38
141
26
82
3.29
6.94
1.2
1.2
—
—
—
0
0
85
470
1.97
6.93
1.9
1.8
—
—
—
0
0
116
712
1.82
6.87
2.6
3.6
0.80
0.83
mmol/l
2.93
110
681
39
157
2.61
6.78
1.5
1.9
4.27
4.31
g/l
0.09
39
150
39
157
2.61
6.78
1.5
1.9
4.01
3.66
g/l
0.70
39
150
39
157
2.61
6.78
1.5
1.9
7.13
7.20
g/l
0.10
39
150
382
3230
1.75
6.70
3.6
3.4
—
—
—
0
0
170
1178
1.67
6.50
1.4
1.3
0.71
1.58
u/ml
1.44
46
346
80
448
1.93
6.27
2.1
1.9
—
—
—
0
0
24
77
3.22
6.25
1.6
1.7
—
—
—
0
0
35
145
2.52
5.76
2.3
1.9
1.34
1.19
ug/l
0.05
35
132
52
259
2.12
5.62
7.6
9.5
25.56
24.88
mmol/l
0.67
52
259
11
13
8.62
5.58
1.2
1.3
—
—
—
0
0
26
94
2.86
5.55
1.1
1.4
169.17
159.18
au/ml
—
6
30
77
443
1.87
5.55
7.4
10.5
0.81
0.88
mmol/l
0.06
60
370
17
47
3.71
5.52
1.3
1.1
—
72.20
—
0
5
19
57
3.42
5.49
1.5
1.4
—
—
—
0
0
89
538
1.79
5.47
4.4
6.4
1.04
1.03
mmol/l
0.08
82
507
53
269
2.08
5.46
1.5
1.4
—
—
—
0
0
30
119
2.62
5.39
1.5
2.0
0.00
0.04
g/l
0.50
30
113
31
126
2.56
5.31
1.9
2.7
—
—
—
0
0
8
6
13.52
5.09
1.3
1.0
—
—
—
0
0
57
305
1.98
5.09
2.9
3.8
1.24
1.23
mmol/l
0.42
50
266
32
136
2.44
5.01
1.5
2.1
0.27
0.90
g/l
0.93
32
125
191
1435
1.53
4.92
3.0
3.4
2.33
2.35
mmol/l
3.02
185
1325
43
210
2.15
4.90
1.7
2.5
33.38
39.37
u/l
1.25
37
193
13
27
4.91
4.52
1.1
1.1
1857.38
1690.93
miu/ml
0.16
13
27
28
118
2.45
4.48
1.4
1.9
0.00
0.00
g/l
-0.00
28
106
23
88
2.69
4.46
1.3
1.9
—
—
—
0
0
11
20
5.60
4.31
1.7
1.4
—
—
—
0
0
11
20
5.60
4.31
1.7
1.4
—
—
—
0
0
109
745
1.59
4.19
2.7
2.6
2.43
2.44
mmol/l
0.25
100
669
10
17
5.98
4.14
2.8
2.5
0.61
0.60
mmol/l
—
10
17
24
98
2.52
4.11
2.0
1.8
136.95
130.87
g/l
0.71
19
78
16
53
3.08
4.00
1.9
1.3
—
—
—
0
0
46
249
1.93
4.00
1.5
1.5
0.20
0.28
mg/l
0.60
19
107
451
4168
1.77
3.86
5.9
5.4
1.76
1.84
mu/l
0.86
430
3925
373
3300
1.50
3.85
4.8
3.5
54.97
44.16
u/l
1.67
362
3159
14
38
3.76
3.82
1.8
1.7
—
—
—
0
0
141
1040
1.49
3.80
2.9
2.3
—
—
—
0
0
39
203
2.00
3.79
1.5
1.5
—
—
—
0
0
27
123
2.26
3.67
1.7
1.7
—
—
—
0
0
7
9
7.87
3.57
1.1
1.2
—
—
—
0
0
26
120
2.23
3.44
1.5
1.6
—
—
—
0
0
395
3565
1.50
3.43
5.1
4.5
14.74
14.46
pmol/l
1.56
375
3325
12
32
3.82
3.41
1.2
2.6
—
—
—
0
0
28
134
2.15
3.40
1.6
1.4
253.43
305.92
ug/g
0.68
20
75
7
10
7.08
3.37
1.0
1.0
—
—
—
0
0
14
48
2.97
3.32
1.8
1.2
—
—
—
0
0
14
48
2.97
3.32
1.8
1.2
—
—
—
0
0
15
55
2.78
3.18
1.4
1.3
—
—
—
0
0
23
105
2.25
3.14
1.6
3.8
1.55
1.98
ratio
0.33
11
59
8
17
4.76
2.93
1.6
1.3
—
—
—
0
0
8
17
4.76
2.93
1.6
1.3
—
—
—
0
0
36
201
1.85
2.90
1.9
1.5
—
—
—
0
0
132
1008
1.42
2.89
3.5
3.3
1093.24
787.88
ng/l
0.64
112
840
11
33
3.38
2.82
1.0
1.0
—
—
—
0
0
10
28
3.62
2.79
1.3
1.4
—
—
—
0
0
6
10
6.06
2.70
1.2
1.2
—
—
—
0
0
56
366
1.60
2.60
3.4
2.5
68.01
73.71
ml/min/173m2
0.57
29
169
19
88
2.20
2.54
1.4
1.5
—
—
—
0
0
99
736
1.43
2.50
3.9
3.7
79.37
386.98
ng/l
1.73
60
494
22
109
2.06
2.50
1.5
1.6
—
—
—
0
0
37
220
1.74
2.45
2.8
2.7
0.62
0.60
%
0.15
37
220
30
170
1.81
2.34
3.8
8.0
1.64
1.64
%
0.00
30
159
17
78
2.22
2.33
1.4
1.4
—
—
—
0
0
37
224
1.70
2.31
2.8
2.7
1.16
1.28
%
0.31
37
224
11
40
2.79
2.28
1.8
1.9
—
—
—
0
0
11
40
2.79
2.28
1.8
1.9
—
—
—
0
0
11
40
2.79
2.28
1.8
1.9
—
—
—
0
0
437
4112
1.47
2.27
6.6
5.8
37.88
38.68
mmol/mol
1.09
428
3925
29
167
1.78
2.16
1.3
1.2
—
—
—
0
0
16
75
2.17
2.10
1.3
1.3
9.00
5.18
u/ml
—
9
28
82
609
1.41
2.08
2.3
2.1
28.94
29.24
s
0.21
76
596
9
31
2.94
2.08
1.6
1.4
66.67
74.03
umol/l
—
9
31
9
31
2.94
2.08
1.1
2.0
—
—
—
0
0
15
70
2.18
2.00
1.2
1.3
—
—
—
0
0
15
70
2.18
2.00
1.2
1.3
—
—
—
0
0
12
52
2.34
1.89
2.3
1.9
—
—
—
0
0
11
46
2.42
1.86
2.4
2.0
—
—
—
0
0
35
223
1.61
1.84
11.9
13.1
16.04
15.91
%
0.09
35
212
6
17
3.56
1.84
1.2
2.2
—
—
—
0
0
6
17
3.56
1.84
1.2
2.2
—
—
—
0
0
6
17
3.56
1.84
1.2
2.2
—
—
—
0
0
15
73
2.09
1.82
1.4
1.6
—
—
—
0
0
48
331
1.50
1.80
1.2
1.4
—
—
—
0
0
7
23
3.07
1.80
1.4
1.3
—
—
—
0
0
37
241
1.58
1.79
2.4
2.0
1585.78
3969.44
u/l
—
9
95
25
147
1.74
1.77
1.2
1.1
4.63
4.16
—
6
32
16
81
2.01
1.76
1.4
1.4
—
—
—
0
0
7
24
2.94
1.73
1.6
1.9
—
—
—
0
0
7
24
2.94
1.73
4.3
3.8
507.43
726.25
u/ml
—
7
24
7
24
2.94
1.73
1.4
1.4
—
—
—
0
0
7
24
2.94
1.73
1.6
1.9
—
—
—
0
0
7
24
2.94
1.73
1.6
1.9
—
—
—
0
0
7
24
2.94
1.73
1.6
1.9
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
5
13
3.87
1.72
1.2
1.1
99.40
97.46
%
—
5
13
5
13
3.87
1.72
2.4
6.7
—
—
—
0
0
20
111
1.83
1.71
1.4
1.5
—
—
—
0
0
6
19
3.18
1.66
1.2
1.5
7.77
8.34
ug/l
—
6
19
34
505
0.65
1.65
3.9
4.4
32.04
31.44
%
0.10
26
361
54
390
1.43
1.62
3.5
3.0
—
—
—
0
0
14
70
2.03
1.60
2.5
2.8
4.72
4.95
kpa
0.69
14
70
7
27
2.61
1.52
6.6
8.7
8.04
635.44
ug/l
—
7
18
10
45
2.25
1.47
1.0
1.1
—
—
—
0
0
7
28
2.52
1.45
1.4
1.2
—
—
—
0
0
12
59
2.06
1.44
1.0
1.2
—
—
—
0
0
9
40
2.27
1.40
1.1
1.5
—
—
—
0
0
9
40
2.27
1.40
3.3
3.8
2.14
2.68
nmol/l
—
9
40
7
29
2.43
1.39
1.4
1.3
—
—
—
0
0
216
1922
1.22
1.37
2.2
1.9
1.39
1.41
mmol/l
0.14
191
1661
5
17
2.96
1.36
2.0
3.1
3.00
4.64
ug/l
—
5
17
22
136
1.65
1.35
2.5
1.8
—
—
—
0
0
9
43
2.11
1.31
1.2
1.1
—
—
—
0
0
6
24
2.52
1.30
1.5
1.1
—
—
—
0
0
6
24
2.52
1.30
6.2
2.6
0.50
0.83
index
—
6
24
8
34
2.37
1.29
1.1
1.5
—
—
—
0
0
23
146
1.60
1.28
2.6
2.0
—
—
—
0
0
16
92
1.76
1.26
1.5
1.6
—
—
—
0
0
13
70
1.88
1.25
1.2
1.2
—
—
—
0
0
35
486
0.70
1.24
1.5
1.7
3.50
3.53
mmol/l
0.08
21
351
29
198
1.49
1.20
1.7
1.6
—
—
—
0
0
14
79
1.79
1.18
1.3
1.3
7.14
4.11
u/ml
—
7
35
5
20
2.51
1.15
1.8
1.2
105.20
116.53
%
—
5
15
14
80
1.77
1.14
1.1
1.1
3.06
1.68
eliau/ml
—
7
39
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
13
74
1.78
1.07
3.2
1.9
13.19
13.16
%
0.05
13
74
7
36
1.96
0.97
1.0
1.1
196.29
224.71
mg/l
—
7
31
405
3886
1.21
0.96
43.2
17.6
330.77
332.79
g/l
4.85
405
3866
14
85
1.67
0.95
2.3
1.9
5.14
5.30
mmol/24h
0.07
14
74
15
232
0.64
0.94
3.9
1.9
2.23
3.00
mg/l
0.45
15
173
164
1466
1.18
0.93
3.2
3.3
8.07
8.07
mmol/l
0.00
146
1259
32
236
1.38
0.92
2.8
3.5
1.20
1.59
mmol/l
0.50
24
181
6
29
2.08
0.89
1.2
1.2
231.40
148.76
iu/ml
—
6
29
149
1329
1.17
0.87
4.1
4.2
2.78
10.45
mg/mmol
6.09
105
835
6
31
1.95
0.84
1.3
1.2
23.28
30.51
nmol/l
—
6
24
6
31
1.95
0.84
1.0
1.0
—
—
—
0
0
10
57
1.77
0.84
6.4
4.9
12.98
69.83
u/ml
—
5
21
16
105
1.54
0.82
1.1
1.1
37.22
18.05
au/ml
—
5
43
12
73
1.66
0.82
1.2
1.2
2.42
2.85
ug/l
0.27
12
62
13
81
1.62
0.82
2.6
3.2
6.01
7.69
pmol/l
0.36
13
81
15
223
0.66
0.80
1.1
1.1
1.49
1.55
g/l
0.65
15
223
29
217
1.36
0.79
1.6
1.5
—
—
—
0
0
80
683
1.20
0.77
1.5
1.8
1.28
1.43
%
2.16
70
605
5
24
2.09
0.74
1.4
2.0
—
—
—
0
0
5
24
2.09
0.74
1.4
2.0
—
—
—
0
0
55
454
1.24
0.74
10.4
6.1
—
—
—
0
0
20
142
1.43
0.73
2.1
2.0
2.38
3.87
iu/l
1.35
12
62
5
25
2.01
0.73
2.2
1.8
3.40
9.19
nmol/l
—
5
20
5
25
2.01
0.73
1.2
1.3
—
—
—
0
0
5
26
1.93
0.71
1.0
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
14
94
1.50
0.67
1.9
2.9
0.32
0.35
iu/ml
—
8
48
54
640
0.83
0.65
1.6
1.9
3.39
3.52
ratio
0.36
38
502
18
129
1.41
0.64
1.2
1.3
446.39
453.78
mg/l
0.04
18
122
5
29
1.73
0.64
1.0
1.8
—
—
—
0
0
23
174
1.34
0.61
1.2
1.3
10.42
9.67
u/l
0.12
18
143
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
101
903
1.15
0.58
1.4
1.5
—
—
—
0
0
8
126
0.63
0.55
1.9
1.6
—
—
—
0
0
7
45
1.56
0.49
2.3
2.7
105.57
105.98
mmol/l
—
7
45
7
45
1.56
0.49
2.3
2.7
1.20
1.19
mmol/l
—
7
45
7
109
0.64
0.49
1.6
1.7
—
—
—
0
0
45
384
1.19
0.47
2.1
2.4
12.56
13.43
nmol/l
0.32
38
357
26
210
1.25
0.46
1.2
1.3
302.40
242.64
miu/ml
0.25
12
101
13
95
1.38
0.44
1.6
2.4
59.13
116.63
ug/min
—
7
55
5
31
1.62
0.43
1.6
1.2
175.58
184.23
pmol/l
—
5
31
16
122
1.32
0.43
1.1
1.1
3.06
1.78
u/ml
—
10
62
5
33
1.52
0.41
1.2
1.3
10168.20
1809.79
e6/l
—
5
19
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
14
183
0.76
0.41
1.2
1.5
—
—
—
0
0
5
35
1.43
0.39
1.0
1.3
8.40
9.66
mm/h
—
5
35
11
148
0.74
0.39
1.4
1.5
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
10
72
1.40
0.37
1.3
1.1
—
—
—
0
0
11
81
1.37
0.36
1.6
1.8
—
—
—
0
0
32
273
1.18
0.36
1.0
1.0
—
—
—
0
0
6
45
1.34
0.34
2.8
4.0
—
—
—
0
0
23
192
1.21
0.32
1.9
1.8
—
—
—
0
0
449
4432
1.12
0.31
5.4
4.9
4.63
4.76
mmol/l
2.32
436
4211
7
54
1.30
0.30
2.9
2.3
9.29
10.89
mmol/l
—
7
54
78
725
1.09
0.26
2.1
2.2
—
—
—
0
0
12
149
0.80
0.26
1.3
1.5
1.12
1.17
ratio
—
6
102
12
149
0.80
0.26
1.3
1.5
0.82
0.96
ratio
—
6
102
12
149
0.80
0.26
1.3
1.5
1.21
1.14
ratio
—
6
102
45
409
1.11
0.23
1.3
1.2
31.90
145.57
u/ml
8.46
21
171
71
661
1.09
0.23
2.1
2.1
—
—
—
0
0
111
1055
1.07
0.22
5.5
4.8
3.22
2.15
ug/l
0.64
103
954
0
11
0.00
0.21
0.0
2.3
—
2.70
—
0
5
20
230
0.86
0.21
1.4
1.1
0.85
0.90
g/l
0.70
20
230
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
11
90
1.23
0.19
1.4
1.5
—
—
—
0
0
13
109
1.20
0.18
1.2
1.3
—
—
—
0
0
61
650
0.93
0.18
3.0
2.8
0.75
0.71
ug/l
0.20
41
381
12
100
1.20
0.18
1.1
1.0
1.17
1.62
u/ml
—
6
46
446
4425
1.07
0.15
5.3
4.8
1.48
1.47
mmol/l
0.10
431
4179
7
90
0.77
0.14
1.3
1.5
73.52
52.20
ug/l
—
7
90
451
4478
1.07
0.14
5.7
5.4
2.69
2.84
mmol/l
3.51
438
4242
44
414
1.07
0.12
1.8
2.1
—
—
—
0
0
36
342
1.06
0.08
1.6
2.1
—
—
—
0
0
422
4212
1.01
0.01
4.9
4.7
5.85
5.84
mmol/l
0.03
400
3961
85
858
0.99
0.01
5.7
4.1
19.24
21.42
%
0.89
47
371
12
125
0.96
0.00
1.7
2.0
180.25
217.83
pmol/l
0.60
12
117
422
4221
1.00
0.00
4.4
4.1
1.38
1.29
mmol/l
1.58
406
3972
0
6
0.00
0.00
0.0
1.0
—
65.67
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
0.67
—
0
9
6
61
0.98
-0.00
1.0
1.2
252.67
297.39
mu/l
—
6
49
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ULCER_ARTHR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ULCER_ARTHR | 1.403 [1.1, 1.79] | 0.006 |
| Birth year | 0.996 [0.99, 1.0] | 0.305 |
During the follow-up period (1.1.1998 — 31.12.2019), 62 out of 907 females with ULCER_ARTHR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ULCER_ARTHR | 1.167 [0.92, 1.49] | 0.212 |
| Birth year | 0.991 [0.98, 1.0] | 0.057 |
During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 698 males with ULCER_ARTHR died.
Mortality risk
Mortality risk for people of age
years, who have ULCER_ARTHR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.127% | 0.177% |
| 5 | 0.763% | 1.472% |
| 10 | 1.952% | 3.667% |
| 15 | 3.853% | 7.007% |
| 20 | 6.948% | 12.123% |
Relationships between endpoints
↥Index endpoint: ULCER_ARTHR – Arthropathy in ulcerative colitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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