Congenital stenosis of pulmonary valve

Q17_CONGENITAL_STENOSIS_OF_PULMONARY_VALVE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q22.1
  • Hospital discharge: ICD-9 7460C
  • Hospital discharge: ICD-8 74663
  • Cause of death: ICD-10 Q22.1
  • Cause of death: ICD-9 7460C
  • Cause of death: ICD-8 74663

2 out of 7 registries used, show all original rules.

276

4. Check minimum number of events

None

276

5. Include endpoints

None

276

6. Filter based on genotype QC (FinnGen only)

242

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 242 135 107
Unadjusted period prevalence (%) 0.05 0.05 0.05
Median age at first event (years) 7.30 6.59 8.19

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
266
Matched controls
2660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
207.4
171
*
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
+∞
114.0
101
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
11.6
86.8
122
181
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
10.2
83.2
152
307
201
Kela drug reimbursment
Chronic cardiac insufficiency
22.8
79.1
62
35
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
14.4
74.3
77
73
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
15.5
62.9
60
49
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
24.6
54.3
40
19
Q21.10
ICD-10 Finland
Persistent ostium secundum
21.9
52.8
41
22
I37.0
ICD-10 Finland
Pulmonary valve stenosis
608.6
52.3
50
*
XF404
NOMESCO Finland
Ambulatory ECG
10.4
50.5
64
79
XF400
NOMESCO Finland
ECG with 12 standard connections
6.3
44.7
101
234
C01AA05
ATC
digoxin; systemic
17.6
44.3
38
25
XF402
NOMESCO Finland
ECG with work load test
9.1
40.2
55
74
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
14.2
37.4
36
29
B01AA03
ATC
warfarin; systemic
7.2
35.8
61
105
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
34.1
32
*
C03DA01
ATC
spironolactone; oral
7.3
33.5
56
94
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
33.0
31
*
WX872
NOMESCO Finland
Intensive care
14.5
32.8
31
24
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
+∞
31.9
30
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
97.1
31.6
34
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.0
30.5
52
89
C03CA01
ATC
furosemide; systemic
5.0
28.7
78
205
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
27.1
76
204
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
56.1
25.8
30
6
TFP20
NOMESCO Finland
Cardiodefibrillation
9.3
25.8
33
40
FM2CE, ,
NOMESCO Finland
8.6
25.7
35
46
TPH07
NOMESCO Finland
Cathetrisation of artery
5.3
24.2
56
127
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
262.7
24.1
24
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
24.1
148
682
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
49.8
22.8
27
6
I48
ICD-10 Finland
Atrial fibrillation and flutter
5.3
21.8
49
108
207
Kela drug reimbursment
Chronic arrhythmias
6.0
21.6
42
81
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
65.6
21.3
24
*
Q87.14
ICD-10 Finland
Noonan's syndrome
119.4
20.9
22
*
31
HP
Congenital heart failure surgery
52.5
20.5
24
5
61
HP
Catheterization and pressure measurement of the left side of the heart
62.6
20.2
23
*
Z2221
NOMESCO Finland
Medical doctor
3.2
18.1
110
485
62
HP
Catheterization and pressure measurement of the right side of the heart
102.0
17.8
19
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
13.9
17.6
30
24
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
16.3
17.6
28
19
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
16.3
17.6
28
19
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.8
17.2
34
66
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
16.8
16
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.9
16.6
57
174
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.0
16.5
53
154
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.6
16.5
44
111
C01BD01
ATC
amiodarone; systemic
18.7
15.9
24
14
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
20.8
15.9
23
12
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.3
15.7
45
120
I50.9
ICD-10 Finland
Heart failure, unspecified
5.5
15.4
32
65
ZXD10
NOMESCO Finland
Scheduled procedure
2.8
15.0
123
626
Q21.30
ICD-10 Finland
Tetralogy of Fallot
84.9
14.7
16
*
Q20.1
ICD-10 Finland
Double outlet right ventricle
158.3
14.6
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
14.3
98
451
XF600
NOMESCO Finland
Bloodpressure measurement
4.2
14.0
41
111
R4110
NOMESCO Finland
Physiotherapy
2.8
13.9
98
457
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
147.2
13.6
14
*
C07AA07
ATC
sotalol; systemic
17.9
13.2
20
12
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
30.1
13.1
17
6
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
33.9
12.7
16
5
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
73.5
12.7
14
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
12.6
12
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
12.6
12
*
WX892
NOMESCO Finland
Monitored bed care
4.1
12.6
38
105
Q20.48
ICD-10 Finland
Single ventricle
136.2
12.5
13
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
39.6
12.3
15
*
WX882
NOMESCO Finland
High dependency care
4.4
12.3
33
83
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
15.6
12.0
19
13
TPH04
NOMESCO Finland
Cathetrisation of vein
2.9
11.8
69
288
I44.2
ICD-10 Finland
Atrioventricular block, complete
17.4
11.8
18
11
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
68.0
11.7
13
*
74734
ICD-8 Finland
Other congenital anomalies of circulatory system, Stenosis, hypoplasia sive aplasia arteriae pulmonalis
+∞
11.5
11
*
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
114.3
10.5
11
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
10.3
105
571
Q21.0
ICD-10 Finland
Ventricular septal defect
41.8
10.0
12
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
57.1
9.7
11
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
57.1
9.7
11
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
5.1
9.7
21
44
Z98.8
ICD-10 Finland
Other specified postsurgical states
18.4
9.5
14
8
XFE00
NOMESCO Finland
Epicardial ultrasonography
11.3
9.4
17
16
Q22.2
ICD-10 Finland
Congenital pulmonary valve insufficiency
+∞
9.4
9
*
ZX120
NOMESCO Finland
Intravenous
3.4
9.4
36
117
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.1
9.3
27
72
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
4.0
9.1
27
73
I50.0
ICD-10 Finland
Congestive heart failure
7.3
9.0
21
31
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
9.0
72
348
Z3226
NOMESCO Finland
Physiotherapist
2.5
9.0
68
320
Q25.0
ICD-10 Finland
Patent ductus arteriosus
14.7
8.8
14
10
Q21.21
ICD-10 Finland
Atrioventricular duct
51.7
8.7
10
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.7
8.7
18
22
Z3231
NOMESCO Finland
Registered nurse
2.2
8.5
97
545
C07AB07
ATC
bisoprolol; oral
2.2
8.4
95
532
AEX
HP
Other pulmonary or pulmonary artery valve procedure
+∞
8.4
8
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
8.4
8
*
K80
ICPC
Cardiac arrhythmia NOS
3.7
8.3
27
78
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
15.1
8.3
13
9
I50.1
ICD-10 Finland
Left ventricular failure
9.4
8.2
16
18
ZXD05
NOMESCO Finland
Urgent procedure
2.2
8.1
92
514
XF622
NOMESCO Finland
Measurement of minute volume of heart
22.8
8.1
11
5
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
11.3
7.9
14
13
WX402
NOMESCO Finland
General anaesthesia
2.2
7.8
80
428
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
7.8
71
362
5253
FHL
Cardiac lung machine
46.4
7.8
9
*
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
46.4
7.8
9
*
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
6.5
7.7
19
31
ZXE00
NOMESCO Finland
One hour or less
2.1
7.6
116
723
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
13.9
7.5
12
9
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
82.3
7.5
8
*
I48.4
ICD-10 Finland
Atypical atrial flutter
82.3
7.5
8
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
82.3
7.5
8
*
XF620
NOMESCO Finland
Examination of circulation with color method
82.3
7.5
8
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
+∞
7.3
7
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
+∞
7.3
7
*
Q21.3
ICD-10 Finland
Tetralogy of Fallot
+∞
7.3
7
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
6.9
7.2
17
26
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
30.9
7.2
9
*
7505
FHL
Funicular lysis and orchidopexy
20.7
7.2
10
5
B01AF02
ATC
apixaban; oral
3.7
7.2
23
66
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
9.2
7.1
14
16
RD210, ,
NOMESCO Finland
4.0
6.9
20
53
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
41.1
6.8
8
*
74629
ICD-8 Finland
Congenital anomalies of heart, Tetralogy of Fallot
71.5
6.5
7
*
Q24.0
ICD-10 Finland
Dextrocardia
71.5
6.5
7
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
71.5
6.5
7
*
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.8
6.4
20
56
Z31.5
ICD-10 Finland
Genetic counselling
2.8
6.3
32
122
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
18.6
6.3
9
5
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
6.3
6
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
6.3
6
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
6.3
6
*
5504
FHL
Subclavian pulmonary anastomosis (Blalock)
+∞
6.3
6
*
74669
ICD-8 Finland
Congenital anomalies of heart, Aliae maleformationes valvulae pulmonaris sive ventriculi dextri
+∞
6.3
6
*
AP3
HP
Catheterization of the right and left side of the heart
+∞
6.3
6
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
6.3
6
*
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
6.3
6
*
Q22.41
ICD-10 Finland
Tricuspid atresia
+∞
6.3
6
*
XF640, ,
NOMESCO Finland
8.0
6.2
13
17
R62.0
ICD-10 Finland
Delayed milestone
3.8
6.2
19
53
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.5
6.1
21
63
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.4
6.0
22
69

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
158
400
8.27
67.67
7.9
4.4
715.96
735.41
ng/l
0.05
148
334
111
485
3.21
18.62
3.3
2.7
—
—
—
0
0
141
742
2.92
16.49
19.1
8.6
1.45
1.13
inr
6.53
116
605
127
639
2.89
16.05
3.3
2.6
—
—
—
0
0
84
353
3.02
14.55
5.5
3.3
1436.03
461.76
ng/l
1.78
68
218
66
281
2.79
10.84
22.9
12.5
—
—
—
0
0
150
939
2.37
10.74
3.8
2.9
—
—
estimate
—
0
0
46
173
3.01
9.40
25.7
14.1
7.42
7.41
ph
—
10
86
57
251
2.62
8.63
22.8
11.7
104.11
104.91
mmol/l
0.56
57
251
34
115
3.24
8.27
32.1
14.1
0.59
0.66
%
0.54
34
115
34
120
3.10
7.71
32.3
13.7
1.56
1.49
%
0.08
34
120
81
445
2.18
7.35
3.0
3.3
1.09
1.17
mg/l
0.09
59
346
167
1202
2.05
7.22
13.0
7.0
6.09
6.33
mmol/l
0.95
161
1124
80
444
2.15
7.04
5.8
4.0
—
—
—
0
0
58
283
2.34
6.96
29.2
16.5
25.06
24.87
mmol/l
0.23
58
283
88
509
2.09
6.94
5.1
3.0
—
—
—
0
0
19
55
3.64
5.85
5.9
18.2
73.77
65.32
%
0.92
19
55
10
9
11.49
5.84
2.4
7.1
134.20
121.89
ug/g
—
10
9
96
604
1.92
5.81
4.1
3.1
18.00
22.39
ng/l
0.33
65
345
90
560
1.92
5.59
3.8
2.8
3.19
2.59
mg/l
0.72
82
492
18
52
3.64
5.56
5.5
18.0
72.42
65.75
%
0.71
18
52
124
858
1.83
5.50
8.8
8.6
—
—
—
0
0
53
277
2.14
5.32
2.5
2.0
—
—
—
0
0
57
308
2.08
5.25
9.1
10.6
7.38
7.37
ph
0.26
34
196
56
302
2.08
5.18
9.1
10.6
1.77
1.19
mmol/l
1.01
51
250
156
1178
1.78
5.00
10.0
8.2
0.56
0.69
%
2.40
149
1120
138
1010
1.76
4.89
20.8
10.7
1.21
1.22
mmol/l
0.72
128
902
155
1179
1.75
4.75
10.1
8.0
3.06
3.03
%
0.06
148
1124
244
2157
2.59
4.63
30.1
14.3
139.19
139.64
mmol/l
2.18
244
2113
155
1185
1.74
4.61
10.1
8.1
9.21
8.48
%
3.37
149
1136
26
106
2.61
4.54
5.9
12.6
0.70
0.62
%
0.65
26
106
47
250
2.07
4.48
8.5
10.7
24.23
23.64
mmol/l
0.99
47
250
42
220
2.08
4.17
15.3
9.6
—
—
—
0
0
7
7
10.23
4.03
1.1
1.9
—
—
—
0
0
160
1268
1.66
3.87
10.3
8.2
0.61
0.55
e9/l
1.67
145
1089
160
1268
1.66
3.87
10.3
8.2
0.04
0.04
e9/l
0.58
145
1087
163
1301
1.65
3.81
10.2
8.1
1.78
2.07
e9/l
4.99
148
1144
7
8
8.95
3.79
1.1
1.9
—
—
—
0
0
7
8
8.95
3.79
1.1
1.6
14.86
10.38
umol/l
—
7
8
17
61
2.91
3.76
3.2
2.6
4.45
3.97
index
0.10
11
33
14
39
3.73
3.76
1.9
1.9
—
—
—
0
0
14
39
3.73
3.76
1.9
1.9
—
—
—
0
0
14
39
3.73
3.76
1.9
1.9
—
—
—
0
0
14
39
3.73
3.76
1.9
1.9
—
—
—
0
0
104
750
1.63
3.60
8.2
7.1
—
—
—
0
0
253
2321
2.84
3.59
25.5
14.1
70.72
68.98
umol/l
0.35
253
2290
13
36
3.74
3.55
3.0
25.0
12.62
11.20
%
0.52
13
36
44
249
1.92
3.52
1.7
1.5
—
—
—
0
0
163
1316
1.62
3.51
10.4
8.6
0.19
0.20
e9/l
0.25
147
1147
12
34
3.65
3.24
1.2
1.2
—
—
—
0
0
8
15
5.46
3.21
2.3
1.1
—
—
—
0
0
33
175
2.01
3.17
3.0
3.9
76.80
69.32
e9/l
0.41
22
118
169
1396
1.58
3.14
12.0
11.2
3.98
3.85
e9/l
0.32
151
1205
6
8
7.64
3.07
1.5
2.0
102.00
91.50
g/l
—
6
8
7
12
5.96
3.04
1.9
6.5
5.01
4.75
kpa
—
7
12
7
12
5.96
3.04
1.9
6.5
6.50
6.00
kpa
—
7
12
75
519
1.62
2.98
3.0
2.6
—
—
—
0
0
13
46
2.92
2.96
1.2
1.3
4.43
3.17
u/ml
—
7
24
5
6
8.46
2.76
2.8
1.7
27.18
45.50
%
—
5
6
98
734
1.53
2.74
1.7
1.6
—
—
—
0
0
144
1171
1.50
2.71
4.8
3.4
93.61
81.07
ug/l
0.47
139
1118
19
86
2.30
2.71
3.5
7.3
271.57
237.10
mg/l
0.14
14
58
60
403
1.63
2.67
3.9
2.7
591.55
568.22
mosm/kgh2o
0.29
53
346
10
30
3.42
2.63
4.7
4.8
7.34
6.41
pmol/l
—
10
30
9
26
3.55
2.50
3.2
1.5
11827.67
10995.05
e6/l
—
9
20
15
66
2.35
2.29
1.0
2.5
—
—
—
0
0
6
13
4.69
2.28
1.5
1.9
76.33
72.31
umol/l
—
6
13
10
35
2.93
2.23
2.2
2.2
—
—
—
0
0
64
457
1.53
2.18
4.2
3.0
5.64
7.34
e6/l
0.32
56
409
10
36
2.85
2.16
6.5
2.4
1.62
1.44
mmol/l
—
10
36
63
453
1.51
2.07
1.7
1.5
19.47
20.43
nmol/l
0.23
54
400
33
204
1.71
2.01
1.5
1.5
926.46
1164.84
nmol/l
1.13
27
152
17
84
2.09
2.00
2.3
2.5
—
—
—
0
0
138
1158
1.40
1.97
13.8
11.0
0.00
0.00
e9/l
0.48
120
911
8
27
3.02
1.95
7.6
2.3
10.38
6.94
mmol/l
—
8
27
6
16
3.81
1.94
6.3
2.1
—
—
—
0
0
6
16
3.81
1.94
3.3
1.1
—
—
—
0
0
9
35
2.63
1.82
2.2
4.2
15.67
8.66
%
—
9
35
7
23
3.10
1.81
2.3
2.2
0.86
0.78
index
—
7
23
9
36
2.55
1.75
2.3
4.1
46.56
64.61
%
—
9
36
39
263
1.57
1.71
2.2
1.7
—
—
—
0
0
17
91
1.93
1.64
2.1
2.0
123.14
112.88
au/ml
—
7
38
8
32
2.55
1.61
2.3
4.3
15.12
24.94
%
—
8
32
34
227
1.57
1.56
1.5
1.2
—
—
—
0
0
28
179
1.63
1.53
1.9
2.0
0.00
0.00
estimate
—
5
44
5
15
3.38
1.53
1.0
1.0
—
—
—
0
0
5
15
3.38
1.53
1.0
1.1
—
—
—
0
0
100
825
1.34
1.48
5.5
4.6
8.37
85.45
e6/l
1.36
73
564
18
103
1.80
1.45
2.8
2.0
204.92
147.58
u/ml
0.47
12
48
6
22
2.77
1.44
1.2
2.7
—
—
—
0
0
17
283
0.57
1.42
1.4
1.3
—
—
—
0
0
9
42
2.18
1.35
2.3
3.7
1080.22
1316.17
e6/l
—
9
30
8
35
2.32
1.28
2.5
4.7
34.25
16.06
%
—
8
35
31
213
1.52
1.28
5.7
3.2
10.13
9.65
g/l
0.19
31
204
15
85
1.81
1.26
2.2
1.7
—
—
—
0
0
8
36
2.26
1.25
6.3
3.6
2.92
3.60
e9/l
—
8
36
245
2340
1.60
1.24
18.5
10.2
—
—
—
0
0
196
1803
1.33
1.24
5.8
4.8
37.06
37.47
mmol/mol
0.28
186
1724
68
544
1.34
1.22
7.0
4.0
7.38
7.39
ph
1.22
57
386
260
2534
2.15
1.20
33.9
19.5
245.91
259.88
e9/l
2.93
260
2478
192
1766
1.31
1.19
5.7
4.2
15.35
14.55
pmol/l
3.83
177
1646
0
34
0.00
1.16
0.0
1.9
—
3.03
—
0
34
8
39
2.08
1.16
2.3
3.8
364.38
168.52
e6/l
—
8
27
5
20
2.53
1.15
2.4
1.4
30.20
33.20
pg
—
5
20
5
20
2.53
1.15
6.2
2.2
—
—
—
0
0
8
40
2.03
1.13
2.3
3.6
349.75
529.46
e6/l
—
8
26
65
793
0.76
1.11
1.5
1.6
0.81
2.42
u/ml
1.75
19
176
5
21
2.41
1.09
1.2
1.3
—
—
—
0
0
5
21
2.41
1.09
1.6
1.5
3.88
6.64
ug/l
—
5
21
90
759
1.28
1.09
2.1
2.0
—
—
—
0
0
7
32
2.22
1.09
6.1
3.1
18.69
32.83
mg/l
—
7
24
260
2539
2.06
1.08
34.5
19.7
135.93
136.94
g/l
0.47
260
2518
260
2537
2.10
1.08
33.8
19.3
29.81
29.83
pg
0.07
260
2518
260
2537
2.10
1.08
38.2
20.2
40.65
40.90
%
0.38
260
2514
260
2535
2.14
1.07
33.8
19.4
89.20
89.04
fl
0.19
260
2516
12
67
1.83
1.06
1.5
2.1
101.17
20.10
ng/l
0.54
12
67
7
33
2.15
1.06
2.0
2.3
0.64
0.64
e9/l
—
7
33
84
705
1.28
1.06
5.2
3.8
22.13
42.99
e6/l
0.85
71
533
5
22
2.30
1.04
1.2
1.2
—
—
—
0
0
60
483
1.31
1.03
4.7
4.1
10.38
10.94
mg/mmol
0.04
43
326
60
483
1.31
1.03
4.1
3.5
53.12
83.08
mg/l
0.54
44
338
49
384
1.34
1.01
3.6
3.5
3.83
2.45
e6/l
0.33
32
198
80
671
1.27
1.01
4.1
3.7
7.28
8.54
mmol/l
1.81
74
604
0
30
0.00
0.98
0.0
1.4
—
—
—
0
0
15
93
1.65
0.96
2.2
2.0
—
—
—
0
0
21
143
1.51
0.93
1.0
1.1
—
—
—
0
0
74
624
1.26
0.89
5.1
3.5
0.20
0.26
e6/l
0.18
62
452
40
312
1.33
0.86
1.3
1.5
497.78
560.00
titre
—
9
56
8
46
1.76
0.83
4.8
2.8
7.39
7.40
ph
—
8
46
6
32
1.89
0.82
1.5
1.1
—
—
—
0
0
219
2085
1.29
0.81
30.7
16.5
13.56
13.29
%
1.94
219
2064
23
165
1.43
0.81
4.5
6.4
0.00
0.20
%
—
8
45
10
58
1.75
0.80
1.3
1.2
—
—
—
0
0
6
33
1.84
0.79
2.8
4.4
0.44
0.37
e9/l
—
6
17
0
25
0.00
0.79
0.0
10.8
—
0.57
—
0
25
202
1908
1.24
0.78
4.4
3.9
5.72
5.68
mmol/l
0.12
195
1778
20
141
1.45
0.77
2.1
1.8
—
—
—
0
0
34
431
0.76
0.77
1.9
1.9
—
—
—
0
0
23
167
1.41
0.76
4.7
6.9
0.00
0.03
%
—
7
39
17
238
0.69
0.71
1.7
2.0
—
—
—
0
0
236
2278
1.32
0.70
23.4
12.5
23.59
21.32
mg/l
0.53
201
1752
7
41
1.73
0.70
9.6
8.3
91.49
91.44
%
—
7
41
7
41
1.73
0.70
5.1
2.4
—
—
—
0
0
5
27
1.87
0.69
2.0
2.1
—
—
—
0
0
22
163
1.38
0.67
3.9
5.8
0.43
0.60
%
—
7
48
68
590
1.20
0.63
4.2
3.5
0.00
0.00
estimate
0.50
24
203
8
51
1.59
0.61
2.0
1.9
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
33.45
—
0
22
10
64
1.58
0.59
1.3
1.4
240.00
285.69
ug/g
—
5
37
23
176
1.34
0.58
4.5
6.1
0.69
0.83
%
—
8
57
10
65
1.56
0.56
5.4
8.5
—
—
—
0
0
18
238
0.74
0.56
1.8
2.0
—
—
—
0
0
6
37
1.64
0.56
1.2
2.3
5.75
5.21
mmol/24h
—
6
32
18
237
0.74
0.54
1.8
2.0
—
—
—
0
0
18
236
0.75
0.53
1.8
2.0
—
—
—
0
0
18
136
1.35
0.50
1.1
1.2
—
—
—
0
0
213
2054
1.19
0.49
6.6
5.0
2.01
1.85
mu/l
1.07
201
1938
10
68
1.49
0.47
6.0
11.2
—
—
—
0
0
29
238
1.25
0.46
1.6
1.9
—
—
—
0
0
11
77
1.45
0.46
1.5
1.4
—
—
—
0
0
47
538
0.85
0.44
4.1
3.3
1.02
1.02
kg/l
0.05
34
333
8
56
1.44
0.43
1.0
1.2
—
—
—
0
0
18
227
0.78
0.42
1.7
2.0
—
—
—
0
0
15
194
0.76
0.42
1.1
1.3
—
21.67
—
0
6
5
33
1.52
0.41
6.8
2.6
7.84
9.35
kpa
—
5
33
0
15
0.00
0.41
0.0
3.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
12
88
1.38
0.40
1.2
1.6
—
12.08
—
0
5
5
34
1.48
0.40
3.4
2.9
15.62
17.16
%
—
5
34
10
71
1.42
0.40
5.2
2.5
53.60
56.25
%
—
10
71
79
721
1.14
0.39
1.9
1.8
88.08
98.42
pmol/l
1.64
48
388
13
169
0.76
0.38
2.3
2.3
—
—
—
0
0
205
1985
1.14
0.37
4.9
4.3
4.34
4.65
mmol/l
4.35
198
1892
205
1986
1.14
0.37
5.4
4.6
2.59
2.78
mmol/l
2.49
197
1885
6
41
1.47
0.36
1.2
1.3
—
—
—
0
0
6
42
1.44
0.36
3.2
3.7
21.40
36.50
%
—
6
42
6
42
1.44
0.36
1.5
3.7
5.03
9.09
u/ml
—
6
42
28
237
1.20
0.35
1.5
1.6
—
—
—
0
0
18
145
1.26
0.34
2.1
1.6
—
—
—
0
0
79
855
0.89
0.34
4.3
3.1
0.00
0.02
estimate
0.50
23
185
50
557
0.87
0.34
1.8
1.8
—
—
—
0
0
19
230
0.81
0.33
2.3
2.4
0.55
0.68
ug/l
—
8
112
47
421
1.14
0.31
2.9
3.2
122.31
90.72
ug/g
0.48
36
334
192
1862
1.11
0.30
4.3
3.7
1.28
1.27
mmol/l
0.04
184
1757
10
129
0.77
0.29
1.1
1.1
—
—
—
0
0
16
193
0.82
0.27
1.8
2.1
—
—
—
0
0
202
1970
1.11
0.26
4.9
4.2
1.34
1.43
mmol/l
2.52
194
1868
9
74
1.22
0.25
1.1
1.4
—
108.33
—
0
6
9
76
1.19
0.25
1.1
1.4
—
—
—
0
0
5
38
1.32
0.23
1.4
2.7
—
—
—
0
0
10
79
1.28
0.22
1.3
1.2
—
—
—
0
0
10
79
1.28
0.22
1.3
1.2
—
—
—
0
0
64
684
0.92
0.22
2.0
2.2
—
—
—
0
0
13
107
1.23
0.22
1.0
1.1
0.85
0.91
g/l
0.29
13
107
0
11
0.00
0.21
0.0
1.4
—
0.00
—
0
11
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
25.80
—
0
10
0
10
0.00
0.21
0.0
7.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
36.80
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
16.20
—
0
5
0
14
0.00
0.20
0.0
6.7
—
8.21
—
0
14
0
14
0.00
0.20
0.0
3.4
—
45.79
—
0
14
0
14
0.00
0.20
0.0
1.1
—
96.44
—
0
9
51
548
0.91
0.20
1.9
1.8
—
—
—
0
0
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
—
—
—
0
0
20
175
1.15
0.19
4.3
2.8
—
—
—
0
0
83
869
0.93
0.17
2.8
2.7
—
—
—
0
0
9
80
1.13
0.15
9.7
6.3
37.00
36.99
°c
—
9
80
42
394
1.08
0.13
1.3
1.3
17.34
30.20
iu/ml
1.04
11
109
27
248
1.10
0.13
1.6
1.5
—
—
—
0
0
93
962
0.95
0.13
4.0
3.2
5.96
6.22
ph
1.88
56
510
12
104
1.16
0.12
1.0
1.1
1.32
1.53
g/l
1.93
12
104
90
870
1.05
0.12
2.1
2.0
1.23
1.42
mmol/l
1.86
84
767
10
114
0.87
0.09
2.3
1.6
—
—
—
0
0
10
87
1.16
0.09
1.6
1.7
—
—
—
0
0
6
55
1.09
0.09
1.0
1.2
—
4.38
—
0
11
12
107
1.13
0.08
2.0
2.5
—
—
—
0
0
7
80
0.87
0.07
1.0
1.2
—
—
—
0
0
9
85
1.06
0.07
1.7
1.6
—
—
—
0
0
9
102
0.88
0.06
1.8
1.2
—
—
—
0
0
22
208
1.06
0.05
1.3
1.4
—
—
—
0
0
17
159
1.07
0.05
2.1
1.6
5.89
6.26
ph
—
9
103
32
333
0.96
0.05
1.3
1.2
—
—
—
0
0
115
1166
0.98
0.05
4.4
3.5
0.00
0.00
estimate
-0.00
22
202
14
132
1.06
0.02
1.0
1.1
—
—
—
0
0
22
212
1.04
0.02
1.3
1.3
184.86
149.72
u/ml
—
7
71
28
272
1.03
0.02
1.3
1.2
—
—
—
0
0
38
388
0.98
0.01
1.6
1.6
—
—
—
0
0
36
367
0.98
0.01
1.3
1.3
19.77
7.21
u/ml
0.29
14
141
18
178
1.01
0.00
1.7
2.4
18272.10
6112.12
u/l
—
7
66
10
101
0.99
0.00
1.3
1.1
—
—
—
0
0
64
641
1.00
0.00
3.8
2.7
0.00
0.02
estimate
0.68
21
174
116
1159
1.00
0.00
4.4
3.5
0.00
7.25
estimate
0.50
25
208
56
563
0.99
0.00
8.2
5.3
—
—
—
0
0
73
733
0.99
0.00
1.9
1.6
2.01
2.03
g/l
0.04
50
420
115
1153
1.00
0.00
4.4
3.4
0.00
0.00
estimate
-0.00
25
214
16
155
1.03
0.00
1.4
1.3
—
26.81
—
0
8
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
0.62
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
51
0.98
-0.00
2.4
1.3
472.80
296.31
mu/l
—
5
42
0
5
0.00
-0.00
0.0
2.6
—
1.80
—
0
5
5
59
0.84
-0.00
2.2
4.1
6.20
594.91
u/ml
—
5
54
20
200
1.00
-0.00
2.8
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
81.40
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
62.33
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
17.5
—
0.72
—
0
6
0
5
0.00
-0.00
0.0
2.6
—
3.92
—
0
5
0
8
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
10.55
—
0
6
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
69
0.87
-0.00
1.8
1.2
—
—
—
0
0
7
69
1.01
-0.00
1.3
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CONGENITAL_STENOSIS_OF_PULMONARY_VALVE – Congenital stenosis of pulmonary valve

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).