otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
580 |
4. Check minimum number of eventsNone |
580 |
5. Include endpointsNone |
580 |
6. Filter based on genotype QC (FinnGen only) |
515 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Abscessus auris externae
Similar endpoints
↥List of similar endpoints to
Abscess of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5026 | 2233 | 2766 |
| Only index persons | 4591 | 2057 | 2534 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.08 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 34.04 | 36.08 | 32.27 |
| Only index persons | 33.71 | 36.09 | 31.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 515 | 275 | 240 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.11 |
| Median age at first event (years) | 41.96 | 39.64 | 44.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 543
- Matched controls
- 5430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.0
ICD-10 Finland
Abscess of external ear
7822.3
307.7
490
5
H60.3
ICD-10 Finland
Other infective otitis externa
42.6
168.8
104
30
H60.9
ICD-10 Finland
Otitis externa, unspecified
12.4
144.3
168
189
H60.8
ICD-10 Finland
Other otitis externa
22.2
114.1
88
47
H60.1
ICD-10 Finland
Cellulitis of external ear
27.0
67.4
47
19
38000
ICD-8 Finland
Otitis externa, Abscessus auris externae
+∞
50.8
48
*
UDC00
NOMESCO Finland
Ear microscopy
6.2
49.7
94
176
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
9.0
39.6
51
62
H60
ICD-10 Finland
Otitis externa
5.4
35.1
75
156
H66.9
ICD-10 Finland
Otitis media, unspecified
4.6
32.7
87
217
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
7.7
24.4
35
48
H01
ICPC
Ear pain/earache
3.2
23.9
109
391
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
87.3
22.9
25
*
H70
ICPC
Otitis externa
7.8
21.8
31
42
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
20.5
105
401
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.7
19.9
32
50
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.3
19.5
82
278
J01MA02
ATC
ciprofloxacin; systemic
2.3
19.2
232
1333
H29
ICPC
Ear symptom/complaint other
3.0
18.9
95
358
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.8
18.0
109
454
J01DA01
ATC
[U] cefalexin
2.2
17.1
363
2575
J01DB01
ATC
cefalexin; oral
3.0
16.1
479
3882
H61.8
ICD-10 Finland
Other specified disorders of external ear
34.5
15.8
20
6
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
18.4
15.3
23
13
A46
ICD-10 Finland
Erysipelas
2.6
14.6
97
420
J01FF01
ATC
clindamycin; systemic
2.2
14.6
170
942
H61.2
ICD-10 Finland
Impacted cerumen
3.7
14.4
47
135
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
6.6
14.2
23
36
H65.0
ICD-10 Finland
Acute serous otitis media
6.7
13.7
22
34
H04
ICPC
Ear discharge
5.1
13.7
29
59
DAA00
NOMESCO Finland
Incision of auricle
+∞
13.6
13
*
TDA90
NOMESCO Finland
Removal wax from ear
13.3
13.5
23
18
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
10.0
12.8
25
26
S02CA02
ATC
flumetasone and antiinfectives; otic
3.6
12.8
43
126
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
12.6
314
2250
SPAT1301
SPAT
No procedures
2.0
12.0
180
1083
SPAT1260
SPAT
Consultation of another employee
2.3
11.8
106
524
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
11.8
178
1073
DC1AD
NOMESCO Finland
Temporalbone CT
14.3
11.0
18
13
N02AX02
ATC
tramadol; systemic, rectal
1.9
11.0
233
1562
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
10.9
92
442
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.8
221
1462
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
10.5
245
1684
SPAT1262
SPAT
Handing over of treatment supplies
2.2
10.4
94
465
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.7
10.3
24
53
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.7
10.3
23
31
H02AB06
ATC
prednisolone; systemic
1.8
10.3
255
1784
H71
ICD-10 Finland
Cholesteatoma of middle ear
11.6
10.1
18
16
R10.0
ICD-10 Finland
Acute abdomen
4.4
9.9
25
59
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
9.7
126
714
J01MA12
ATC
levofloxacin; systemic
2.1
9.6
103
544
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
9.5
54
215
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
9.5
81
390
M79.6
ICD-10 Finland
Pain in limb
1.7
9.1
248
1764
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
7.2
9.1
21
30
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
19.0
9.0
13
7
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
8.9
63
279
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
8.9
142
861
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
8.7
84
425
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
50.8
8.7
10
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.1
8.7
84
426
EBA00
NOMESCO Finland
Extraction of tooth
1.7
8.3
218
1526
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
8.2
145
903
SPAT1263
SPAT
Sampling
1.7
8.2
228
1619
H70.1
ICD-10 Finland
Chronic mastoiditis
33.9
8.1
10
*
R02
ICPC
Shortness of breath/dyspnoea
2.2
7.9
75
376
J01AA02
ATC
doxycycline; systemic
1.8
7.9
400
3320
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
7.9
48
198
L72.1
ICD-10 Finland
Trichilemmal cyst
2.6
7.8
45
181
D07XC01
ATC
betamethasone; topical
2.2
7.7
70
345
J46
ICD-10 Finland
Status asthmaticus
4.1
7.7
21
53
N03AX16
ATC
[U] pregabalin
1.9
7.7
121
727
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.3
7.6
28
87
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
18.7
7.6
11
6
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
7.5
117
701
R03BA02
ATC
budesonide; inhalant
1.9
7.5
107
623
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.4
209
1479
R03AC02
ATC
salbutamol; inhalant
1.6
7.4
304
2366
N06AX16
ATC
venlafaxine; oral
2.0
7.4
91
504
S29
ICPC
Skin symptom/complaint other
1.9
7.3
111
659
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
3.8
7.3
22
60
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.9
7.2
33
117
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
7.2
121
739
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.7
7.1
22
61
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.0
134
851
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
7.0
80
431
SPAT1310
SPAT
Counselling related to known health issue
1.7
7.0
168
1138
S10
ICPC
Boil/carbuncle
2.5
6.9
42
174
SPAT1252
SPAT
Overall medication plan or its review
2.7
6.8
35
133
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
6.8
120
745
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
6.7
64
322
N05BA01
ATC
diazepam; systemic, rectal
2.0
6.7
72
379
H65.2
ICD-10 Finland
Chronic serous otitis media
6.6
6.7
16
25
U05
ICPC
Urination problems other
2.8
6.5
33
124
A02BC02
ATC
pantoprazole; systemic
1.6
6.4
341
2783
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
6.4
257
1964
Z3231
NOMESCO Finland
Registered nurse
1.7
6.4
143
945
J01FA06
ATC
roxithromycin; oral
1.6
6.4
202
1459
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.3
6.4
46
206
L73.2
ICD-10 Finland
Hidradenitis suppurativa
5.3
6.4
18
35
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.1
6.3
26
87
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
6.3
120
759
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.3
108
663
SPAT1153
SPAT
Removal of sutures
1.7
6.3
148
993
H61.0
ICD-10 Finland
Perichondritis of external ear
+∞
6.3
6
*
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.3
94
554
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
6.2
58
289
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.2
109
673
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.2
171
1193
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
4.0
6.2
17
43
H13
ICPC
Plugged feeling ear
1.8
6.2
97
579
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.2
53
256
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
7.8
6.2
13
17
NDJ64
NOMESCO Finland
Internal fixation of fracture of wrist or hand wire, rod, cerclage or pin
4.2
6.1
16
39
C09CA06
ATC
candesartan; oral
1.7
6.1
125
806
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
8.7
6.1
12
14
A11
ICPC
Chest pain NOS
2.3
6.0
46
211
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
4.0
6.0
17
44
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.0
229
1723
R51.80
ICD-10 Finland
Headache
1.8
6.0
98
592
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
108
557
2.17
10.78
8.9
6.2
1.06
1.05
mmol/l
0.19
102
522
265
1909
1.76
9.40
15.8
11.7
1.20
1.19
inr
0.23
224
1583
220
1524
1.75
8.80
4.6
3.3
8.15
8.07
mmol/l
0.07
188
1317
256
1853
1.72
8.72
7.1
5.1
35.95
36.41
g/l
0.66
233
1756
332
2631
1.67
7.65
7.1
5.2
6.84
6.58
mmol/l
1.22
320
2457
205
1435
1.69
7.64
4.2
2.7
58.02
62.79
u/l
0.35
185
1353
404
3383
1.76
7.50
4.7
4.2
12.13
10.42
mm/h
1.52
375
3184
194
1358
1.67
7.13
5.6
4.1
19.37
9.46
mg/mmol
0.93
132
868
303
2387
1.61
6.80
6.9
6.8
12.83
11.16
umol/l
0.69
286
2289
20
57
3.60
6.21
1.5
1.4
—
—
—
0
0
99
598
1.80
6.08
7.6
6.7
103.92
104.40
mmol/l
0.35
99
598
328
2673
1.57
6.07
10.2
9.9
4.40
4.06
e9/l
1.72
301
2335
161
1122
1.62
5.82
2.8
2.2
2.69
2.90
mg/l
0.56
142
958
183
1321
1.58
5.68
2.5
2.1
154.64
259.69
u/l
1.12
171
1261
163
1147
1.60
5.63
3.1
2.8
340.11
344.77
umol/l
0.25
148
1031
414
3596
1.64
5.57
4.7
4.3
14.58
14.64
pmol/l
0.18
379
3336
501
4603
2.14
5.50
23.0
14.2
22.72
23.02
mg/l
0.08
424
3731
241
1867
1.52
5.38
2.1
2.0
99.73
95.92
pmol/l
0.72
130
995
47
231
2.13
5.24
1.7
1.4
—
—
—
0
0
81
485
1.79
5.09
7.9
9.3
0.55
0.86
mmol/l
0.22
69
405
138
954
1.60
5.07
3.7
2.5
6.71
5.92
e6/l
0.19
122
869
168
1220
1.55
4.97
4.2
2.9
0.87
0.39
e6/l
0.76
132
858
396
3439
1.56
4.97
9.8
8.1
83.60
77.64
u/l
1.22
379
3272
217
1668
1.50
4.91
5.7
3.5
32.04
73.80
ng/l
0.58
128
1080
347
2943
1.50
4.75
5.7
4.3
62.20
82.23
e6/l
—
5
47
108
722
1.62
4.52
3.0
3.7
0.81
0.82
mmol/l
0.21
103
687
166
1228
1.51
4.43
1.4
1.3
2.01
1.92
u/ml
0.03
39
363
241
1923
1.46
4.38
9.0
6.7
1.20
1.21
mmol/l
1.22
228
1786
56
316
1.86
4.27
3.7
2.3
4.75
7.23
ug/l
0.70
49
289
262
2131
1.44
4.27
10.8
7.2
1.21
1.21
mmol/l
0.33
235
1846
70
426
1.74
4.16
6.1
3.8
1.00
1.86
mmol/l
1.28
63
367
107
730
1.58
4.09
3.9
2.4
13.48
13.87
umol/l
0.21
102
681
46
249
1.93
3.98
2.0
2.4
6553.71
4460.63
u/l
0.18
15
107
81
520
1.66
3.96
2.3
1.8
—
—
—
0
0
111
771
1.55
3.92
2.8
2.7
2.43
2.43
mmol/l
0.10
95
687
102
700
1.56
3.79
2.4
1.9
—
—
—
0
0
294
2475
1.41
3.79
4.8
3.6
19.27
6.21
estimate
0.29
77
504
26
115
2.32
3.77
1.9
1.6
—
—
—
0
0
93
629
1.58
3.68
2.0
1.7
1166.35
1145.42
nmol/l
0.08
68
477
91
613
1.58
3.66
3.8
2.4
23.33
23.74
%
0.11
85
583
99
682
1.55
3.62
3.3
2.2
30.27
29.26
s
1.01
92
664
147
1103
1.46
3.56
1.9
1.8
0.98
1.20
mg/l
0.82
109
838
154
1166
1.45
3.55
1.8
1.6
19.72
20.25
nmol/l
0.16
128
1010
493
4614
1.74
3.51
25.5
16.1
3.98
3.96
mmol/l
1.32
487
4513
290
2456
1.39
3.50
4.9
3.5
0.00
0.00
estimate
0.50
74
498
294
2499
1.38
3.45
4.9
3.6
0.35
0.01
estimate
0.56
75
467
492
4610
1.72
3.38
25.4
16.0
139.53
139.69
mmol/l
0.70
487
4520
75
496
1.59
3.26
2.5
1.9
—
—
—
0
0
181
1432
1.40
3.22
4.4
3.0
25.21
84.35
e6/l
0.68
143
1068
20
85
2.40
3.19
6.6
2.0
11.68
6.53
pmol/l
1.74
20
85
68
442
1.62
3.18
3.8
2.5
36.29
140.84
u/l
0.46
62
368
378
3373
1.40
3.17
4.0
3.4
55.35
44.56
u/l
1.14
359
3220
55
339
1.69
3.15
2.2
2.5
69.79
72.84
ml/min/173m2
0.18
24
143
462
4280
1.53
3.15
6.0
5.2
1.82
1.85
mu/l
0.15
425
4033
239
1991
1.36
3.06
2.9
2.5
73.26
74.17
nmol/l
0.20
218
1825
44
258
1.77
3.01
5.6
3.9
23.33
24.36
mmol/l
1.64
44
258
180
1443
1.37
2.91
4.3
3.3
2.35
2.35
mmol/l
0.07
162
1322
47
285
1.71
2.87
6.8
4.0
114.39
80.71
ng/l
1.34
40
257
272
2338
1.33
2.72
3.9
3.1
133.47
109.35
ug/l
0.82
252
2210
469
4389
1.50
2.72
19.8
13.1
88.09
87.18
ml/min/173m2
0.34
442
4024
57
373
1.59
2.61
2.4
2.4
0.22
0.22
g/l
0.23
52
351
19
87
2.23
2.60
1.4
1.5
—
—
—
0
0
62
415
1.56
2.58
3.5
2.9
—
—
—
0
0
253
2164
1.32
2.58
3.0
2.8
—
—
estimate
—
0
0
67
460
1.52
2.50
11.1
6.5
—
—
—
0
0
367
3314
1.33
2.50
3.4
3.4
—
—
—
0
0
41
250
1.69
2.48
4.6
3.4
1.80
1.71
mmol/l
0.07
30
185
20
97
2.10
2.40
1.0
1.1
3.64
1.27
u/ml
0.30
12
50
141
1118
1.35
2.39
1.9
1.6
—
—
—
0
0
452
4230
1.41
2.33
8.0
5.8
40.64
38.64
mmol/mol
3.20
423
4021
31
178
1.79
2.31
1.7
2.2
1.50
1.39
g/l
0.29
25
163
170
1392
1.32
2.31
4.3
3.0
0.00
0.02
estimate
1.15
57
409
202
1695
1.31
2.30
3.6
3.6
49.02
30.64
u/l
0.51
190
1614
94
703
1.41
2.27
3.4
2.9
2.39
2.12
e6/l
0.13
52
321
7
18
3.92
2.26
1.1
1.2
—
—
—
0
0
110
846
1.38
2.26
1.3
1.3
1.03
10.41
u/ml
4.40
36
341
108
830
1.38
2.22
5.6
3.9
117.75
391.17
ng/l
1.36
83
587
48
316
1.57
2.17
5.2
3.5
1.22
1.23
mmol/l
0.35
42
278
7
19
3.72
2.15
1.1
1.3
—
—
—
0
0
220
1885
1.28
2.10
4.9
3.4
0.03
0.02
estimate
0.09
63
426
116
912
1.35
2.07
1.3
1.3
12.28
31.81
iu/ml
4.77
29
281
25
141
1.81
2.00
2.2
2.9
—
—
—
0
0
23
128
1.83
1.92
1.2
1.5
355.50
296.31
ug/g
0.78
16
75
161
1338
1.29
1.92
5.0
3.6
0.00
0.01
estimate
1.23
73
477
30
182
1.69
1.89
2.1
1.7
—
—
—
0
0
38
246
1.59
1.87
3.8
3.1
0.63
0.63
%
0.01
38
246
14
66
2.15
1.83
2.1
1.4
—
—
—
0
0
5
12
4.19
1.82
2.6
1.4
67.58
55.39
ng/l
—
5
12
18
94
1.95
1.82
3.4
3.5
27.44
34.32
umol/l
1.54
18
88
38
248
1.57
1.81
3.8
3.1
1.74
1.38
%
0.48
38
248
7
23
3.07
1.80
1.1
1.3
—
—
—
0
0
11
47
2.37
1.78
1.2
2.2
31.27
33.15
pg
0.55
11
47
25
147
1.73
1.77
1.5
1.8
—
—
—
0
0
20
111
1.83
1.71
1.1
1.2
4.39
3.44
u/ml
0.10
15
61
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
111
1.83
1.71
8.1
3.4
0.31
0.36
iu/ml
0.12
12
62
139
1150
1.28
1.71
3.8
3.3
1500.40
1054.50
ng/l
0.69
115
968
108
865
1.31
1.69
1.8
1.7
460.46
15395172.41
pmol/l
0.50
85
760
22
127
1.76
1.66
1.1
1.2
—
—
—
0
0
503
4854
1.49
1.66
14.3
11.2
28.54
27.40
u/l
0.62
490
4741
20
113
1.80
1.62
1.2
1.2
—
1.03
—
0
7
7
26
2.71
1.58
1.1
1.3
—
—
—
0
0
134
1114
1.27
1.58
2.4
2.3
—
—
—
0
0
19
107
1.80
1.56
1.4
1.2
—
—
—
0
0
45
316
1.46
1.56
1.7
1.6
—
—
—
0
0
458
4364
1.32
1.54
5.7
4.6
6.10
5.84
mmol/l
2.70
422
4067
96
767
1.31
1.54
3.4
2.7
1.54
0.88
e6/l
0.72
55
381
218
1923
1.22
1.50
2.1
1.9
1.48
1.38
mmol/l
0.69
186
1672
7
28
2.52
1.45
1.0
1.0
1384.29
1586.11
miu/ml
—
7
28
9
39
2.33
1.43
1.4
1.6
—
—
—
0
0
135
1136
1.25
1.43
4.6
3.6
1.02
1.02
kg/l
0.17
82
759
71
551
1.33
1.40
3.0
3.0
8.60
7.68
umol/l
0.15
62
490
14
74
1.92
1.40
1.6
1.4
—
—
—
0
0
51
377
1.39
1.37
1.3
1.3
195.55
152.69
u/ml
0.32
11
159
35
241
1.48
1.36
1.5
1.6
—
—
—
0
0
25
160
1.59
1.34
1.6
2.0
—
—
—
0
0
17
98
1.76
1.32
1.5
1.4
—
—
—
0
0
97
793
1.27
1.31
2.5
2.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
24
2.52
1.30
1.3
2.7
165.17
123.21
%
—
6
24
90
730
1.28
1.30
1.9
1.8
1.50
1.47
%
0.15
82
654
21
130
1.64
1.28
1.1
1.2
—
—
—
0
0
24
158
1.54
1.16
1.4
1.4
—
—
—
0
0
471
4545
1.27
1.12
5.8
4.7
4.52
4.65
mmol/l
2.10
449
4307
475
4592
1.27
1.09
6.4
5.3
2.67
2.76
mmol/l
1.39
448
4336
18
113
1.61
1.07
3.3
2.3
122.99
54.34
ug/min
0.43
12
61
102
862
1.23
1.05
2.7
2.2
—
—
—
0
0
19
123
1.56
1.01
1.2
1.3
172.62
239.19
u/ml
0.70
14
75
468
4525
1.25
1.01
5.6
4.6
1.40
1.44
mmol/l
1.37
443
4265
34
249
1.39
1.00
1.6
1.5
377.14
291.27
mu/l
0.50
28
227
49
621
0.77
0.98
1.7
2.0
3.48
3.51
ratio
0.05
35
491
5
23
2.18
0.98
1.2
1.2
—
—
—
0
0
15
92
1.65
0.98
1.3
1.3
—
—
—
0
0
19
124
1.55
0.98
2.1
4.2
102.09
91.30
mg/l
0.07
14
110
6
27
2.24
0.93
2.2
4.2
—
—
—
0
0
21
142
1.50
0.93
1.1
1.2
—
3.11
—
0
14
518
5087
1.40
0.86
32.2
21.5
4.50
4.56
e12/l
2.18
512
4993
17
112
1.53
0.86
1.5
1.4
—
—
—
0
0
29
214
1.38
0.84
2.1
1.4
11.70
8.71
u/l
0.49
22
176
11
65
1.71
0.83
1.2
1.2
—
—
—
0
0
6
32
1.88
0.82
1.0
1.2
3.85
1.96
mmol/l
—
6
32
23
164
1.42
0.81
1.3
1.5
1.31
1.18
g/l
1.01
23
156
0
25
0.00
0.79
0.0
3.1
—
1.12
—
0
25
517
5083
1.36
0.77
32.4
21.6
254.98
252.00
e9/l
0.46
512
5002
18
124
1.47
0.76
2.1
4.2
44.33
48.68
mg/l
0.08
13
111
12
75
1.61
0.75
1.0
1.1
0.24
0.45
u/ml
—
5
26
22
159
1.40
0.73
1.4
1.5
0.26
0.23
g/l
0.42
22
151
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
25
2.01
0.73
1.2
1.2
—
—
—
0
0
9
56
1.62
0.72
1.1
1.3
—
—
—
0
0
9
59
1.53
0.68
2.6
1.3
219.44
372.13
pmol/l
—
9
52
38
303
1.27
0.68
2.9
4.1
4.71
4.66
pmol/l
0.07
33
271
443
4303
1.16
0.66
4.9
4.0
1.37
1.28
mmol/l
1.27
416
4031
50
415
1.23
0.65
1.8
2.0
—
—
—
0
0
38
467
0.80
0.64
1.4
1.7
3.46
3.46
mmol/l
0.01
22
336
5
29
1.73
0.64
1.2
1.1
154.40
120.25
iu/ml
—
5
29
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
19
138
1.39
0.63
7.8
4.6
1.65
1.37
mg/l
0.65
19
123
12
79
1.53
0.63
1.2
1.7
—
—
—
0
0
8
50
1.61
0.61
1.0
1.0
—
—
—
0
0
29
227
1.29
0.61
1.3
1.4
283.74
248.23
miu/ml
—
9
112
8
51
1.58
0.60
4.8
1.8
17.75
24.20
nmol/l
—
8
46
13
89
1.47
0.58
1.2
1.2
—
—
—
0
0
19
141
1.36
0.57
1.2
1.1
—
4.42
—
0
29
8
55
1.46
0.56
1.1
1.7
—
—
—
0
0
16
117
1.38
0.53
1.5
1.4
150.33
160.87
au/ml
—
6
36
6
40
1.51
0.51
1.2
1.2
—
—
—
0
0
6
40
1.51
0.51
1.2
1.2
—
—
—
0
0
11
75
1.48
0.51
1.2
1.1
1.52
1.42
g/l
0.20
11
69
58
503
1.17
0.50
2.2
2.1
—
—
—
0
0
16
211
0.75
0.48
1.2
1.1
1.47
1.53
g/l
0.57
16
211
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
7
50
1.41
0.45
1.0
1.1
—
—
—
0
0
7
50
1.41
0.45
2.7
3.5
—
—
—
0
0
17
218
0.77
0.43
1.3
1.1
0.90
0.91
g/l
0.05
17
218
5
31
1.62
0.43
5.6
4.1
2210.00
940.06
mg
—
5
31
8
57
1.41
0.42
1.1
1.4
—
—
—
0
0
33
277
1.20
0.42
1.1
1.0
—
—
—
0
0
32
268
1.21
0.42
1.8
1.7
0.13
0.28
mg/l
1.96
12
129
150
1404
1.09
0.40
5.3
4.8
2.49
2.09
ug/l
0.26
137
1278
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
2.9
—
51.05
—
0
19
0
19
0.00
0.39
0.0
1.0
—
5.03
—
0
19
5
36
1.39
0.38
3.4
2.4
—
—
—
0
0
5
37
1.35
0.37
1.2
1.3
—
—
—
0
0
40
347
1.16
0.37
1.6
1.4
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
6
42
1.43
0.35
1.2
1.2
—
—
—
0
0
36
311
1.17
0.35
1.8
1.4
23.11
21.28
iu/l
0.16
31
267
6
43
1.40
0.35
1.0
1.2
—
90.00
—
0
6
15
187
0.80
0.32
1.4
1.5
1.02
1.24
ratio
—
6
127
15
187
0.80
0.32
1.4
1.5
1.36
0.94
ratio
—
5
127
15
187
0.80
0.32
1.4
1.5
0.92
1.18
ratio
—
5
127
6
47
1.28
0.32
2.5
3.3
2.22
2.76
nmol/l
—
6
47
6
47
1.28
0.32
1.2
1.2
—
—
—
0
0
11
83
1.33
0.32
1.0
1.1
—
—
—
0
0
15
185
0.81
0.30
1.4
1.5
—
—
—
0
0
19
157
1.22
0.30
1.3
1.3
—
—
—
0
0
7
57
1.23
0.29
7.9
2.8
105.29
105.42
mmol/l
—
7
57
7
57
1.23
0.29
7.9
2.8
1.21
1.19
mmol/l
—
7
57
84
779
1.09
0.29
1.4
1.5
—
—
—
0
0
11
85
1.30
0.28
1.8
1.5
—
—
—
0
0
11
85
1.30
0.28
3.6
4.1
—
2810.30
—
0
10
25
290
0.86
0.28
1.2
1.3
—
—
—
0
0
10
127
0.78
0.25
1.4
1.6
50.21
53.43
ug/l
—
10
127
6
85
0.70
0.24
1.3
1.1
—
—
—
0
0
20
172
1.17
0.22
1.5
1.7
—
—
—
0
0
31
346
0.89
0.22
1.5
1.6
1122.93
973.65
mu/l
0.31
24
295
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
10.5
—
5.94
—
0
10
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
5
43
1.16
0.21
2.0
1.5
—
—
—
0
0
11
89
1.24
0.21
1.1
1.1
2.68
2.17
eliau/ml
—
5
44
11
89
1.24
0.21
2.6
1.3
—
—
—
0
0
11
89
1.24
0.21
2.6
1.3
—
—
—
0
0
11
89
1.24
0.21
1.5
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
21
240
0.87
0.20
1.7
2.5
22.97
34.32
u/ml
0.60
21
230
6
48
1.25
0.20
1.8
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
52
1.16
0.19
1.0
1.3
0.17
0.17
nmol/l
—
6
37
6
53
1.13
0.18
1.2
1.2
—
—
—
0
0
54
505
1.08
0.17
5.1
4.3
32.22
30.93
%
0.39
36
353
21
236
0.89
0.17
1.4
1.5
—
—
—
0
0
5
66
0.76
0.17
1.0
1.1
—
—
—
0
0
12
102
1.18
0.15
2.3
2.0
—
—
—
0
0
9
80
1.13
0.15
1.3
1.1
—
1.43
—
0
5
23
207
1.12
0.15
1.3
1.3
—
—
—
0
0
9
82
1.10
0.15
1.3
1.2
—
—
—
0
0
20
219
0.91
0.11
1.9
1.9
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
114
1114
1.03
0.08
3.8
4.2
23.37
21.47
%
0.55
53
471
51
492
1.04
0.07
3.0
2.5
12.08
13.71
nmol/l
0.64
41
459
12
131
0.91
0.05
1.7
1.6
—
—
—
0
0
13
141
0.92
0.05
1.9
1.8
—
—
—
0
0
14
151
0.93
0.05
1.1
1.1
—
—
—
0
0
10
110
0.91
0.05
1.5
1.2
—
—
—
0
0
14
150
0.93
0.04
1.1
1.1
—
—
—
0
0
12
127
0.94
0.01
1.7
1.5
—
—
—
0
0
84
833
1.01
0.01
2.7
2.9
0.74
0.71
ug/l
0.10
53
484
10
94
1.07
0.01
2.7
1.8
—
—
—
0
0
16
165
0.97
0.00
1.5
1.5
—
—
—
0
0
10
104
0.96
0.00
1.3
1.6
3.98
3.64
mmol/l
—
10
95
14
137
1.02
0.00
1.2
1.3
—
—
—
0
0
12
118
1.02
0.00
1.3
1.6
773.42
437.12
mg/l
0.59
12
111
40
402
0.99
0.00
3.0
4.6
5.26
38.10
ug/l
0.99
30
334
14
141
0.99
0.00
2.2
2.1
3.91
4.14
iu/l
—
7
62
5
51
0.98
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
5.83
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
51
0.98
0.00
1.2
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.16
—
0
5
5
58
0.86
-0.00
1.2
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
-0.00
1.1
1.1
—
14.29
—
0
38
0
7
0.00
-0.00
0.0
12.1
—
10.50
—
0
7
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
0.60
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
80
1.00
-0.00
1.0
1.1
—
2.02
—
0
21
5
56
0.89
-0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_ABSC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.518 [1.23, 1.88] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.427 |
During the follow-up period (1.1.1998 — 31.12.2019), 227 out of 1895 females with H8_EXT_ABSC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.552 [1.3, 1.85] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2212 males with H8_EXT_ABSC died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_ABSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.136% | 0.284% |
| 5 | 0.798% | 1.831% |
| 10 | 2.06% | 4.494% |
| 15 | 4.252% | 8.106% |
| 20 | 7.656% | 13.681% |
Relationships between endpoints
↥Index endpoint: H8_EXT_ABSC – Abscess of external ear
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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