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Mental and behavioural disorders associated with the puerperium

F5_MENTPUER

postpartum depression: An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F53
  • Hospital discharge: ICD-8 2944
  • Cause of death: ICD-10 F53
  • Cause of death: ICD-8 2944

2 out of 7 registries used, show all original rules.

495

4. Check minimum number of events

None

495

5. Include endpoints

None

495

6. Filter based on genotype QC (FinnGen only)

425

Control definitions (FinnGen only)

Control exclude
F5_BEHAVE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F50-F59
Name in latin
Perturbationes mentis et modi se gerendi puerperio adjunctae non alibi classificatae

Similar endpoints

List of similar endpoints to Mental and behavioural disorders associated with the puerperium based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 425 425 -
Unadjusted period prevalence (%) 0.15 0.15 -
Median age at first event (years) 30.48 30.48 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
450
Matched controls
4500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F53.0
ICD-10 Finland
Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
3392.8
213.2
189
*
F53.1
ICD-10 Finland
Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
149.5
135
*
N05AH04
ATC
quetiapine; oral
10.1
136.6
236
444
F51.0
ICD-10 Finland
Nonorganic insomnia
+∞
136.6
124
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
13.7
133.4
147
154
N05AH03
ATC
olanzapine; systemic
13.1
124.7
140
150
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
15.2
96.3
92
75
N05BA04
ATC
oxazepam; oral
7.0
95.5
249
678
F53.9
ICD-10 Finland
Puerperal mental disorder, unspecified
+∞
86.3
80
*
29440
ICD-8 Finland
Psychosis associated with other physical conditions, Childbirth
+∞
82.9
77
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
11.5
74.2
84
88
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.4
61.1
161
418
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
11.9
59.3
64
62
N05AX08
ATC
risperidone; systemic
7.9
57.1
88
135
N05AX12
ATC
aripiprazole; systemic
7.9
55.6
85
129
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
17.6
54.5
46
29
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
9.5
53.2
68
83
N05AB03
ATC
perphenazine; systemic, rectal
12.1
52.3
55
51
N05AA02
ATC
levomepromazine; systemic
13.2
51.4
51
43
N06AB06
ATC
sertraline; oral
4.8
47.4
139
386
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
11.6
46.3
50
48
N05AN01
ATC
lithium; oral
10.6
45.0
52
55
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.5
43.6
139
409
N05CD07
ATC
temazepam; oral
7.5
42.9
67
103
N03AG01
ATC
valproic acid; systemic, rectal
6.2
42.0
81
155
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
11.5
41.7
45
43
N06AX11
ATC
mirtazapine; oral
3.7
40.8
203
812
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.4
39.1
121
346
N06AB04
ATC
citalopram; systemic
3.9
38.3
154
531
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
7.9
37.7
55
78
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
6.1
34.6
66
124
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
5.1
34.6
82
188
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
7.8
32.9
48
68
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
5.6
32.8
69
142
N05BA06
ATC
lorazepam; systemic, sublingual
7.0
32.3
52
82
N05CF01
ATC
zopiclone; oral
3.4
32.0
161
632
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.8
31.1
79
191
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
10.7
30.4
34
34
N05AD01
ATC
haloperidol; systemic
11.0
30.1
33
32
N06AX16
ATC
venlafaxine; oral
3.6
29.4
125
439
P76
ICPC
Depressive disorder
4.2
28.2
87
244
P29
ICPC
Psychological sympt/compl other
4.0
28.1
94
280
P01
ICPC
Feeling anxious/nervous/tense
3.2
26.5
145
590
P99
ICPC
Psychological disorders other
5.8
25.8
50
95
O99.80
ICD-10 Finland
The fear of childbirth
3.6
25.5
99
325
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.7
25.1
95
306
IGY02
NOMESCO Finland
Psychiatric monitoring contact
6.2
25.1
45
79
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
7.1
25.1
39
59
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
10.6
25.0
28
28
N06AB03
ATC
fluoxetine; oral
3.8
24.7
88
272
F53.8
ICD-10 Finland
Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
24.2
23
*
N05AC02
ATC
thioridazine; oral
8.5
24.2
32
40
P06
ICPC
Sleep disturbance
3.6
23.8
92
300
N06AB10
ATC
escitalopram; oral
2.9
23.7
161
732
Z2446
NOMESCO Finland
Social worker
4.5
21.9
58
144
ZY010
NOMESCO Finland
Hospital outpatient
4.3
21.4
59
151
N03AX09
ATC
lamotrigine; oral
4.2
20.8
60
159
N05AF03
ATC
chlorprothixene; systemic
6.9
20.8
33
51
N06AB05
ATC
paroxetine; oral
4.4
20.1
54
135
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.6
20.0
33
53
G47.0
ICD-10 Finland
Disorders of initiating and maintaining sleep [insomnias]
+∞
18.9
18
*
IHZ05, ,
SPAT
4.2
18.8
54
142
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.9
18.3
105
429
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.7
18.2
123
548
ZY000
NOMESCO Finland
Hospital inpatient
14.5
18.0
30
22
N04AA02
ATC
biperiden; systemic
7.6
18.0
26
36
N05AA01
ATC
chlorpromazine; systemic, rectal
13.9
17.7
30
23
SPAT1240
SPAT
Therapeutic discussion
3.0
17.7
93
362
F31.8
ICD-10 Finland
Other bipolar affective disorders
6.1
17.4
31
54
IGY99
NOMESCO Finland
Other psychiatric treatment contact
6.2
17.2
30
51
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
5.0
16.9
38
82
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.0
16.9
38
82
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.6
16.8
41
95
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
18.8
16.7
25
14
P03
ICPC
Feeling depressed
2.8
16.6
96
393
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
7.4
16.3
24
34
N06AX03
ATC
mianserin; oral
6.0
16.1
29
51
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
6.3
15.8
27
45
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
6.6
15.2
25
40
F41.8
ICD-10 Finland
Other specified anxiety disorders
4.3
15.1
41
103
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
15.8
15.0
24
16
N05CF02
ATC
zolpidem; oral
2.7
15.0
94
400
N05BA01
ATC
diazepam; systemic, rectal
3.2
15.0
66
231
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
4.5
14.8
37
87
F32
ICD-10 Finland
Depressive episode
3.6
14.3
51
156
N06AX12
ATC
bupropion; oral
3.0
14.2
68
249
N06AA12
ATC
doxepin; systemic
5.3
14.0
29
58
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
4.0
13.9
41
110
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.2
13.4
37
94
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.1
12.9
58
205
N06AX26
ATC
vortioxetine; oral
3.0
12.8
61
223
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
5.7
12.7
24
44
P72
ICPC
Schizophrenia
6.1
11.9
21
36
F20.9
ICD-10 Finland
Schizophrenia, unspecified
5.7
11.8
22
40
F31
ICD-10 Finland
Bipolar affective disorder
9.0
11.7
24
28
F34.1
ICD-10 Finland
Dysthymia
4.1
11.6
33
86
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
8.4
11.2
24
30
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
25.8
11.2
15
6
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.0
11.0
190
1213
R3110
NOMESCO Finland
Psychosocial training
4.5
10.9
27
63
N05BA12
ATC
alprazolam; oral
2.9
10.9
55
207
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.8
10.9
34
95
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
13.3
10.7
18
14
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.1
10.6
46
159
F43.8
ICD-10 Finland
Other reactions to severe stress
3.9
10.5
31
83
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.2
10.5
108
568
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.6
10.4
35
103
IGP01
NOMESCO Finland
Psychiatric family contact
19.3
10.3
15
8
P74
ICPC
Anxiety disorder/anxiety state
3.0
10.3
47
167
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
7.8
10.3
23
31
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
24.0
10.3
14
6
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.9
10.3
249
1768
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.1
10.1
44
152
Z2445
NOMESCO Finland
Psychologist
3.7
10.1
33
95
2988A
ICD-9 Finland
Other nonorganic psychoses, Other and unspecified reactive psychosis
41.0
10.0
12
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.1
10.0
28
72
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.4
9.8
25
60
ZYC01
NOMESCO Finland
Remote contact by phone
3.1
9.6
42
146
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
5.1
9.4
20
41
N05BE01
ATC
buspirone; oral
4.8
9.4
21
45
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.8
9.2
244
1759
IHZ04, ,
SPAT
5.2
9.2
19
38
IER01
NOMESCO Finland
Psychoeducation, group
16.0
9.1
14
9
F33.3
ICD-10 Finland
Recurrent depressive disorder, current episode severe with psychotic symptoms
37.5
9.1
11
*
N06AX05
ATC
trazodone; oral
7.7
9.0
20
27
IGY02, ,
SPAT
7.1
8.9
21
31
P98
ICPC
Psychosis NOS/other
11.0
8.9
16
15
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
14.4
8.7
14
10
ZXY83
NOMESCO Finland
Social worker in multidisciplinary team
51.0
8.7
10
*
F39
ICD-10 Finland
Unspecified mood [affective] disorder
4.5
8.7
21
48
G02CB01
ATC
bromocriptine; systemic
4.2
8.6
23
57
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
8.5
100
549
29999
ICD-8 Finland
Unspecified psychosis
28.1
8.5
11
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
8.5
48
192
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.1
8.4
18
23
N06AX22
ATC
agomelatine; oral
4.8
8.4
19
41
W78
ICPC
Pregnancy
1.8
8.3
178
1193
C07AA05
ATC
propranolol; systemic
2.0
8.3
115
670
AA400
NOMESCO Finland
Electroconvulsive therapy
14.8
8.2
13
9
R53
ICD-10 Finland
Malaise and fatigue
1.9
8.2
131
799
IGY99, ,
SPAT
4.7
8.2
19
42
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
4.7
8.2
19
42
N05AF05
ATC
zuclopenthixol; systemic
12.0
8.1
14
12
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.9
8.1
122
731
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
22.5
8.0
11
5
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
7.5
8.0
18
25
N06AB08
ATC
fluvoxamine; oral
4.4
8.0
20
47
A06AD11
ATC
lactulose; oral
2.7
7.9
44
175
IEY01
NOMESCO Finland
Psychoeducation, individual
9.7
7.8
15
16
WVA20, ,
SPAT
4.0
7.8
22
57
A10BA02
ATC
metformin; oral
2.0
7.8
94
521
F28
ICD-10 Finland
Other nonorganic psychotic disorders
15.4
7.8
12
8
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
7.6
7.7
17
23
IBC98
NOMESCO Finland
Other child protection assessment
45.8
7.7
9
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.0
7.7
104
598
ZXH06, ,
SPAT
3.2
7.7
30
97
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.3
7.7
29
92
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
6.9
7.7
18
27
F99
ICD-10 Finland
Mental disorder, not otherwise specified
4.2
7.6
20
49
IBZ02
NOMESCO Finland
Somatic assessment of psychiatric patient
25.5
7.6
10
*
IGV01
NOMESCO Finland
Psychiatric network contact
10.3
7.6
14
14
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.4
7.5
19
45
D11
ICPC
Diarrhoea
2.1
7.5
80
422
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
7.9
7.4
16
21
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.9
7.4
111
662
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.3
199
1415
R21
ICPC
Throat symptom/complaint
1.8
7.3
155
1028
G47.9
ICD-10 Finland
Sleep disorder, unspecified
4.4
7.3
18
42
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.9
7.2
34
123
N06AX21
ATC
duloxetine; oral
2.2
7.2
66
328
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
7.2
163
1099
ZXY49
NOMESCO Finland
Other health care provider
20.4
7.2
10
5
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
12.3
7.1
12
10
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.8
7.1
156
1043
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.5
7.1
24
71
P73
ICPC
Affective psychosis
14.1
6.9
11
8
188
Kela drug reimbursment
Psychosis requiring demanding treatment
8.5
6.9
14
17
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.0
6.9
77
414
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.1
6.8
69
357
ZYY79
NOMESCO Finland
Other indirect service without contact with patient
40.7
6.8
8
*
F50.9
ICD-10 Finland
Eating disorder, unspecified
40.7
6.8
8
*
SPAT1254
SPAT
Administration of medicine
2.2
6.7
56
268
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.7
6.7
165
1135
SPAT1097
SPAT
Recording of ECG
2.4
6.7
46
202
SPAT1389
SPAT
Visit based on need for special support
3.2
6.7
26
84
F41
ICD-10 Finland
Other anxiety disorders
4.1
6.7
18
45
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
6.0
6.7
17
29
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.9
6.6
19
50
D01AE15
ATC
terbinafine; topical
3.1
6.5
27
91
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.8
6.5
109
671
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
8.3
6.4
13
16
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.3
6.4
48
220
AA1AD
NOMESCO Finland
CT of head and brain
1.9
6.3
84
479
R11
ICD-10 Finland
Nausea and vomiting
2.3
6.2
49
230

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
198
1162
2.26
15.55
2.6
2.9
2.34
2.35
mmol/l
0.71
189
1079
232
1504
2.12
13.64
6.2
6.1
1.22
1.22
mmol/l
0.23
203
1303
122
613
2.36
13.54
1.8
1.5
436.50
67276474.68
pmol/l
1.59
111
547
352
2730
2.33
12.46
6.6
7.0
71.35
73.32
u/l
0.63
344
2590
205
1310
2.04
12.10
5.6
5.4
1.22
1.22
mmol/l
0.21
192
1215
274
1957
2.02
11.66
4.8
4.2
6.29
6.26
mmol/l
0.07
248
1747
205
1377
1.90
9.90
2.0
1.9
99.47
97.34
pmol/l
0.29
113
758
82
397
2.30
9.66
1.7
1.5
1271.30
1104.39
nmol/l
0.72
67
314
141
847
1.97
9.44
1.8
1.5
19.25
21.28
nmol/l
0.96
130
745
145
891
1.93
9.02
4.2
3.7
7.40
7.40
ph
0.44
98
613
191
1303
1.81
8.41
1.9
2.0
—
—
—
0
0
352
2900
1.98
8.23
3.6
2.8
30.50
32.09
u/l
0.27
341
2796
35
121
3.05
8.05
2.7
1.7
—
—
—
0
0
157
1023
1.82
7.95
2.8
2.6
19.16
110.16
ng/l
0.53
71
462
92
502
2.05
7.94
2.5
2.2
7941.26
6178.42
u/l
0.22
44
230
48
200
2.57
7.81
3.3
1.9
—
—
—
0
0
243
1820
1.73
7.45
2.4
2.4
72.95
74.82
nmol/l
0.57
229
1707
169
1144
1.76
7.43
3.1
2.2
—
—
—
0
0
411
3635
2.51
7.33
5.0
3.8
5.70
5.60
mmol/l
1.01
391
3427
195
1383
1.72
7.21
3.0
3.2
29.58
27.66
u/l
0.32
183
1324
328
2703
1.79
6.87
5.6
4.0
6135.83
3438.47
e6/l
—
6
32
190
1358
1.69
6.70
4.4
4.4
36.25
37.31
g/l
1.92
182
1288
192
1382
1.68
6.56
3.7
3.2
20.82
58.09
e6/l
2.00
125
865
255
1979
1.67
6.49
3.1
2.7
—
—
estimate
—
0
0
65
336
2.09
6.43
3.8
4.0
4.64
4.70
pmol/l
0.13
55
306
108
667
1.81
6.33
4.2
3.7
—
—
—
0
0
391
3438
2.05
6.26
7.0
4.9
14.04
14.28
pmol/l
1.27
378
3271
45
203
2.35
6.19
2.3
3.4
0.89
1.84
mmol/l
0.82
38
179
102
626
1.81
6.09
2.9
2.3
500.00
503.75
mosm/kgh2o
0.05
88
544
228
1747
1.62
5.89
4.0
3.0
6.54
6.26
ph
2.86
123
1030
43
195
2.33
5.85
5.5
3.8
1.24
1.22
mmol/l
1.01
33
166
142
969
1.68
5.80
1.9
2.1
2.65
2.56
mg/l
0.21
126
843
13
19
7.01
5.77
1.7
1.3
—
—
—
0
0
272
2184
1.62
5.73
4.8
3.3
0.00
6.20
estimate
0.80
63
470
154
1077
1.65
5.71
3.4
2.4
53.94
59.08
u/l
0.56
141
1006
254
2016
1.60
5.54
6.9
6.1
0.04
0.04
e9/l
0.08
218
1780
253
2008
1.59
5.50
6.7
6.1
0.54
0.52
e9/l
0.62
217
1777
424
3889
2.56
5.45
8.3
5.7
1.57
1.74
mu/l
3.73
410
3733
271
2192
1.59
5.39
4.7
3.4
0.00
0.01
estimate
0.80
61
455
44
210
2.21
5.32
2.8
3.4
5.96
5.82
kpa
0.26
44
203
261
2100
1.58
5.25
7.1
6.4
0.18
0.17
e9/l
0.20
228
1883
267
2161
1.58
5.22
4.6
3.3
0.00
0.00
estimate
-0.00
62
471
429
3971
2.72
5.13
14.5
10.8
18.16
18.71
mg/l
0.14
364
3128
43
209
2.17
4.98
2.7
3.5
7.37
7.38
ph
0.40
25
119
274
2247
1.56
4.93
10.2
8.8
4.07
3.95
e9/l
0.48
240
1970
161
1173
1.58
4.91
2.0
1.8
—
—
—
0
0
81
495
1.78
4.84
1.3
1.3
24.02
25.01
iu/l
0.09
68
435
422
3892
2.35
4.83
5.0
4.4
2.83
2.85
mmol/l
0.16
403
3718
91
576
1.73
4.81
2.0
2.1
2.42
2.41
mmol/l
0.25
84
508
108
717
1.67
4.79
2.9
2.4
7.37
9.70
e6/l
0.79
98
640
228
1803
1.54
4.78
4.9
5.3
9.18
9.63
umol/l
0.46
219
1713
160
1170
1.57
4.78
5.0
3.4
0.00
0.00
estimate
-0.00
60
458
419
3856
2.26
4.77
4.4
4.0
1.47
1.55
mmol/l
4.60
402
3681
384
3438
1.80
4.67
5.8
4.6
36.94
37.16
mmol/mol
0.23
368
3288
153
1113
1.57
4.65
5.2
5.8
—
—
—
0
0
295
2478
1.55
4.62
3.8
3.2
57.85
59.59
ug/l
0.14
281
2364
255
2077
1.53
4.59
7.0
6.1
2.06
2.02
e9/l
0.24
223
1882
199
1545
1.52
4.45
1.9
1.9
—
—
—
0
0
133
946
1.58
4.42
5.0
3.3
1.02
2.61
kg/l
0.50
84
634
148
1080
1.55
4.39
3.2
2.7
12.92
77.65
e6/l
1.50
117
802
54
300
1.91
4.37
2.3
1.5
—
—
—
0
0
54
300
1.91
4.37
2.4
1.5
—
—
—
0
0
418
3866
2.14
4.32
4.5
4.0
4.76
4.80
mmol/l
0.44
401
3705
54
302
1.90
4.28
2.4
1.5
—
—
—
0
0
65
389
1.78
4.16
2.2
2.2
389.91
379.80
nmol/l
0.15
57
366
49
273
1.89
3.94
2.5
1.5
—
—
—
0
0
18
65
2.84
3.90
5.5
2.2
7.40
7.41
ph
0.29
18
65
67
413
1.73
3.87
1.9
1.5
—
—
—
0
0
73
462
1.69
3.84
3.4
3.2
0.80
0.83
mmol/l
1.03
67
444
159
1207
1.49
3.83
5.8
6.1
—
—
—
0
0
32
154
2.16
3.83
1.5
2.3
4.38
4.73
umol/l
0.19
24
115
30
141
2.21
3.80
2.3
3.2
5.11
5.19
kpa
0.13
30
134
219
1773
1.46
3.79
11.6
9.0
0.00
0.00
e9/l
0.78
179
1458
226
1842
1.46
3.77
6.1
6.1
8.08
8.12
%
0.06
215
1743
125
905
1.53
3.77
3.2
2.5
0.18
0.30
e6/l
0.77
99
637
195
1547
1.46
3.74
2.6
2.1
—
—
—
0
0
137
1013
1.51
3.74
3.7
3.3
6.53
7.73
mmol/l
2.68
119
881
97
665
1.58
3.72
2.3
2.1
—
—
—
0
0
173
1343
1.47
3.70
2.1
1.8
—
—
—
0
0
43
236
1.91
3.62
2.6
1.3
—
—
—
0
0
34
173
2.04
3.54
6.9
8.3
—
—
—
0
0
229
1889
1.43
3.49
6.2
5.9
56.59
56.81
%
0.12
219
1813
75
493
1.63
3.41
2.7
2.3
2.63
2.48
g/l
1.17
63
454
392
3605
1.68
3.38
3.9
3.4
1.27
1.17
mmol/l
2.29
373
3420
163
1270
1.44
3.35
1.4
1.3
0.54
1.94
u/ml
2.14
56
361
57
350
1.72
3.35
2.6
2.3
36.59
28.93
u/l
0.63
51
293
80
539
1.59
3.29
2.8
2.4
13.74
14.43
umol/l
0.35
74
497
223
1844
1.41
3.28
6.2
6.0
2.58
2.71
%
0.47
211
1738
47
275
1.79
3.26
3.3
3.4
7.40
7.34
ph
2.06
38
201
223
1846
1.41
3.25
6.3
6.1
0.65
0.68
%
0.40
211
1732
50
299
1.76
3.22
2.3
1.5
—
—
—
0
0
435
4144
2.49
3.21
11.6
9.5
22.36
23.41
u/l
1.01
428
4050
53
323
1.73
3.20
1.5
1.6
421.76
300.53
mu/l
0.71
46
292
20
85
2.42
3.20
1.7
3.8
—
—
—
0
0
36
198
1.89
3.04
5.2
6.7
1.34
1.15
mmol/l
0.45
36
193
26
127
2.11
3.03
5.8
6.8
23.99
24.50
mmol/l
0.31
26
127
228
1913
1.39
2.98
6.2
6.0
30.21
29.54
%
0.51
219
1829
47
284
1.73
2.93
5.2
6.3
104.94
104.84
mmol/l
0.05
47
284
31
165
1.94
2.89
1.3
1.4
0.11
0.20
mg/l
—
10
60
12
38
3.22
2.87
1.4
3.2
26.92
31.30
umol/l
0.51
12
33
203
1679
1.38
2.86
4.7
3.2
0.00
0.03
estimate
1.60
51
388
23
110
2.15
2.84
1.6
2.4
1.43
1.38
%
0.06
23
110
66
440
1.59
2.84
2.7
2.4
21.09
22.84
%
0.49
60
407
106
784
1.46
2.81
1.6
1.6
1058.88
1007.77
mu/l
0.15
92
654
137
1066
1.41
2.75
4.7
4.0
—
—
—
0
0
50
315
1.66
2.69
6.9
6.0
1.11
1.03
mmol/l
1.21
44
286
97
716
1.45
2.59
1.8
1.5
—
—
—
0
0
11
37
3.02
2.50
4.5
2.0
2.10
2.51
mmol/l
—
6
25
11
37
3.02
2.50
4.5
2.0
9.53
9.60
kpa
0.05
11
37
11
37
3.02
2.50
4.5
2.0
4.95
4.96
kpa
0.02
11
37
6
12
5.05
2.41
1.5
2.1
28.18
15.00
umol/l
—
6
12
18
84
2.19
2.38
5.0
3.6
36.97
36.97
°c
0.05
18
84
5
8
6.30
2.37
1.4
1.3
—
—
—
0
0
38
232
1.70
2.32
2.7
3.9
71.46
69.48
ng/l
0.07
32
215
6
13
4.66
2.28
1.5
1.1
6.63
7.55
nmol/l
—
6
13
39
243
1.66
2.22
2.0
2.5
0.23
0.22
g/l
0.25
34
235
110
853
1.38
2.21
4.7
4.3
13.78
8.51
mg/mmol
0.23
66
523
21
108
1.99
2.19
1.6
2.3
0.53
0.59
%
0.48
21
108
64
451
1.49
2.16
1.5
1.4
—
—
—
0
0
52
352
1.54
2.12
1.6
1.5
—
—
—
0
0
33
200
1.70
2.08
5.8
10.1
96.64
96.76
%
0.10
33
193
52
355
1.53
2.04
4.9
3.3
—
—
—
0
0
52
357
1.52
1.99
1.6
1.6
—
—
—
0
0
32
195
1.69
1.99
6.5
10.3
119.22
119.89
g/l
0.08
32
190
148
1221
1.32
1.96
7.2
6.7
1.04
1.06
inr
0.31
125
1011
70
513
1.43
1.94
1.3
1.2
95.68
158.91
u/ml
0.99
36
214
5
11
4.58
1.94
1.0
1.2
—
—
—
0
0
50
344
1.51
1.90
1.5
1.5
1.24
1.24
mm
0.01
39
246
36
230
1.61
1.88
6.3
9.4
7.41
7.42
ph
0.36
18
128
111
885
1.34
1.86
1.9
2.0
228.58
197.35
u/l
0.09
106
847
40
264
1.57
1.84
2.6
1.3
—
—
—
0
0
106
844
1.33
1.79
3.8
3.6
82.83
42.42
mg/l
0.34
62
539
38
250
1.57
1.77
1.1
1.2
—
—
—
0
0
35
226
1.59
1.77
4.4
3.2
—
—
—
0
0
22
125
1.80
1.75
7.3
9.4
94.92
95.20
%
0.20
22
125
51
360
1.47
1.73
1.7
1.7
—
—
—
0
0
29
181
1.64
1.68
1.7
2.0
0.00
0.01
estimate
0.49
11
71
6
19
3.19
1.66
1.2
2.1
140.50
140.42
nmol/l
—
6
19
8
31
2.61
1.66
3.4
3.9
—
—
—
0
0
11
49
2.28
1.65
3.9
2.2
—
—
—
0
0
35
231
1.56
1.63
6.2
9.2
1.04
0.78
mmol/l
0.11
28
182
62
461
1.40
1.61
1.6
1.5
54.62
59.51
ug/l
0.43
56
387
14
71
2.00
1.55
1.7
2.1
761.57
175.10
ug/l
0.52
14
60
29
187
1.59
1.50
1.2
1.2
16.65
12.22
u/l
0.52
24
154
22
132
1.70
1.49
1.1
1.2
—
—
—
0
0
110
905
1.29
1.46
1.9
1.7
0.97
0.86
mg/l
0.27
88
673
29
189
1.57
1.44
12.7
9.0
6.78
7.23
mmol/l
0.16
29
184
55
410
1.39
1.42
2.0
2.7
5.85
5.52
umol/l
0.10
45
353
9
40
2.27
1.41
2.6
1.8
15.12
17.22
%
—
9
40
98
799
1.29
1.39
2.3
2.2
295.58
296.74
umol/l
0.04
88
731
26
167
1.59
1.37
2.2
2.4
4.25
5.27
iu/l
—
10
70
5
17
2.96
1.36
1.6
1.1
0.00
0.00
estimate
—
5
17
49
361
1.40
1.36
1.8
1.9
0.00
0.05
estimate
0.78
13
94
179
1571
1.23
1.35
1.8
1.8
1.37
1.29
mmol/l
0.61
157
1388
126
1064
1.26
1.35
1.6
1.4
2.18
2.04
g/l
0.69
80
692
55
416
1.37
1.31
1.1
1.2
—
—
—
0
0
20
122
1.67
1.29
5.0
9.3
26.16
24.98
mmol/l
0.42
20
114
9
45
2.02
1.24
1.3
1.3
—
—
—
0
0
85
693
1.28
1.21
2.1
2.6
70.52
96.47
ug/g
1.24
65
538
33
231
1.46
1.21
6.7
9.2
12.07
13.76
kpa
1.86
33
220
33
231
1.46
1.21
6.7
9.2
5.42
5.10
kpa
0.86
33
219
6
26
2.32
1.19
1.8
3.0
—
—
—
0
0
35
249
1.44
1.19
2.8
2.5
1.74
1.73
%
0.01
28
224
10
50
2.02
1.17
1.8
2.8
21.62
141.11
ug/min
—
5
35
60
469
1.32
1.17
1.6
1.4
—
—
—
0
0
429
4185
1.54
1.12
14.6
10.0
—
—
—
0
0
62
490
1.31
1.12
2.1
2.7
111.84
230.93
ng/l
0.46
30
245
15
89
1.71
1.09
1.2
1.9
—
—
—
0
0
5
22
2.29
1.03
1.2
2.3
1.20
1.19
mmol/l
—
5
22
5
23
2.19
0.98
1.2
2.3
3.94
3.85
mmol/l
—
5
23
5
23
2.19
0.98
1.2
2.3
108.20
104.87
mmol/l
—
5
23
37
277
1.37
0.97
7.9
5.3
0.00
0.16
%
—
8
55
99
846
1.22
0.95
1.5
1.5
—
—
—
0
0
6
28
2.16
0.92
3.0
1.3
33.00
31.61
pg
—
6
28
27
194
1.42
0.90
1.3
1.2
—
—
—
0
0
60
488
1.26
0.90
4.1
3.4
4.42
4.78
e9/l
0.22
51
452
18
121
1.51
0.84
1.1
1.3
—
—
—
0
0
18
122
1.50
0.81
5.2
12.5
15.64
16.13
%
0.36
18
115
0
24
0.00
0.79
0.0
1.1
—
0.80
—
0
13
0
24
0.00
0.79
0.0
3.3
—
48.83
—
0
12
100
871
1.19
0.79
1.3
1.3
5.51
9.00
u/ml
0.39
44
385
30
390
0.75
0.76
2.1
1.8
—
—
—
0
0
145
1307
1.16
0.76
4.0
2.8
0.00
0.01
estimate
1.34
53
388
60
500
1.23
0.74
2.4
2.4
4.74
4.85
e6/l
0.02
30
229
9
55
1.65
0.74
3.6
1.9
8.51
8.17
kpa
—
9
55
9
55
1.65
0.74
2.6
3.2
—
—
—
0
0
7
38
1.86
0.74
1.0
1.1
—
—
—
0
0
10
158
0.62
0.72
1.3
1.3
—
—
—
0
0
5
26
1.93
0.71
1.0
1.1
1208.00
1639.00
miu/ml
—
5
26
7
42
1.68
0.68
1.1
2.1
—
—
—
0
0
5
27
1.86
0.68
16.2
5.6
7.62
6.64
mmol/l
—
5
22
33
415
0.78
0.67
1.4
1.4
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
7
44
1.60
0.65
1.6
1.7
—
—
—
0
0
36
288
1.27
0.64
7.1
4.7
0.56
0.90
%
—
9
72
16
112
1.44
0.64
1.3
1.4
339.06
388.48
mg/l
0.66
16
104
48
574
0.82
0.64
1.2
1.3
—
—
—
0
0
14
96
1.47
0.62
1.4
1.3
—
—
—
0
0
22
165
1.35
0.61
2.6
2.4
65.52
75.72
e9/l
1.16
14
109
0
21
0.00
0.60
0.0
1.3
—
149.79
—
0
21
22
168
1.33
0.56
1.6
1.7
9.29
7.73
u/ml
—
9
40
34
276
1.25
0.56
7.4
4.8
0.00
0.13
%
—
7
60
14
99
1.43
0.54
3.9
8.8
—
—
—
0
0
105
948
1.14
0.54
1.4
1.4
14.02
21.91
iu/ml
2.06
32
278
54
463
1.19
0.53
1.1
1.2
—
—
—
0
0
50
426
1.20
0.53
1.3
1.3
—
—
—
0
0
12
83
1.46
0.52
2.9
3.4
2.71
2.03
index
—
7
39
16
118
1.37
0.51
2.2
3.5
374.86
168.84
mg/l
—
7
45
33
271
1.23
0.50
6.7
4.6
0.56
0.67
%
—
9
64
7
45
1.56
0.49
2.3
3.3
23.49
23.65
mu/l
—
7
45
7
47
1.50
0.47
2.7
2.5
—
—
—
0
0
50
434
1.17
0.44
2.0
1.9
—
—
—
0
0
13
95
1.38
0.44
1.1
1.0
1.09
3.03
eliau/ml
—
7
46
36
304
1.20
0.43
1.0
1.3
—
—
—
0
0
12
162
0.73
0.43
1.3
1.4
74.83
85.64
pmol/l
0.16
12
157
0
17
0.00
0.40
0.0
3.8
—
184.24
—
0
17
14
106
1.33
0.39
17.0
7.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
144.40
113.43
pmol/l
—
5
35
21
169
1.25
0.39
2.0
1.7
—
—
—
0
0
13
170
0.76
0.39
1.4
1.6
1.10
1.18
g/l
0.56
13
161
11
146
0.75
0.36
3.2
2.2
—
—
—
0
0
6
44
1.37
0.34
1.7
1.6
75.67
61.22
%
—
6
44
10
74
1.36
0.32
1.2
1.4
—
—
—
0
0
10
75
1.34
0.30
1.0
1.1
—
—
—
0
0
13
163
0.79
0.30
1.4
1.7
0.21
0.23
g/l
0.49
13
155
12
95
1.27
0.26
1.3
1.2
5.67
6.86
u/ml
—
6
35
76
706
1.09
0.26
1.3
1.4
836.67
629.07
titre
0.21
12
161
5
75
0.66
0.26
1.8
1.4
0.90
0.55
g/l
—
5
55
13
157
0.82
0.22
1.1
1.2
—
—
—
0
0
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
23.20
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
15
126
1.20
0.21
1.0
1.1
—
—
—
0
0
15
126
1.20
0.21
1.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
17
145
1.18
0.21
1.0
1.1
—
—
—
0
0
6
48
1.25
0.20
1.2
1.1
1.47
1.41
g/l
—
6
43
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.02
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.2
—
—
—
0
0
6
49
1.23
0.20
2.3
15.2
13.17
10.41
mmol/l
—
6
44
6
50
1.20
0.20
2.3
14.9
106.17
105.42
mmol/l
—
6
45
7
59
1.19
0.18
1.1
1.0
—
—
—
0
0
7
60
1.17
0.18
1.1
1.1
—
—
—
0
0
7
62
1.13
0.17
1.4
1.2
—
—
—
0
0
5
68
0.73
0.17
1.0
1.5
58.66
37.33
nmol/l
—
5
60
5
69
0.72
0.17
1.0
1.0
—
—
—
0
0
8
69
1.16
0.16
2.0
2.2
—
—
—
0
0
10
83
1.21
0.15
2.6
2.9
—
23.04
—
0
5
16
182
0.87
0.15
1.3
1.8
—
—
—
0
0
12
102
1.18
0.15
1.2
1.4
302.17
320.09
ug/g
—
6
53
11
94
1.17
0.13
2.5
9.3
0.80
0.88
%
0.25
11
86
22
202
1.09
0.10
1.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.8
1.4
—
—
—
0
0
32
301
1.07
0.09
1.5
1.4
180.39
241.63
miu/ml
0.45
18
166
5
47
1.06
0.09
1.8
1.4
0.26
0.35
g/l
—
5
31
5
47
1.06
0.09
1.8
1.4
3.12
2.81
g/l
—
5
31
5
47
1.06
0.09
1.8
1.4
6.74
5.83
g/l
—
5
31
5
48
1.04
0.09
1.0
1.1
255.00
199.23
mg/l
—
5
39
5
48
1.04
0.09
1.2
1.3
—
—
nmol/l
—
0
0
6
57
1.05
0.08
6.5
2.1
7.77
6.20
pmol/l
—
6
57
10
113
0.88
0.08
1.0
1.2
—
—
—
0
0
5
63
0.79
0.08
1.6
2.3
—
—
—
0
0
186
1833
1.03
0.07
3.0
2.4
—
—
—
0
0
8
75
1.07
0.07
1.1
1.0
—
—
—
0
0
8
78
1.03
0.07
1.3
1.1
—
—
—
0
0
9
85
1.06
0.07
3.8
10.2
0.95
1.12
mmol/l
—
9
71
51
527
0.96
0.06
1.5
1.6
3.51
3.33
mmol/l
0.47
30
359
22
232
0.95
0.05
2.9
4.3
2.55
6.82
ug/l
1.36
16
174
24
252
0.95
0.05
1.0
1.2
0.80
0.85
g/l
0.54
24
252
29
278
1.05
0.04
1.3
1.4
—
—
—
0
0
361
3597
1.02
0.03
19.7
14.0
332.20
331.88
g/l
0.28
361
3567
35
341
1.03
0.02
3.1
2.1
6.19
6.25
ph
0.18
24
219
55
542
1.02
0.01
1.3
1.2
—
—
—
0
0
23
236
0.97
0.00
1.0
1.1
0.49
0.57
ratio
—
5
28
25
245
1.02
0.00
1.0
1.1
1.54
1.58
g/l
0.30
25
245
10
103
0.97
0.00
2.6
8.6
1.35
1.61
%
—
10
95
29
287
1.01
0.00
1.1
1.1
—
191.43
—
0
7
24
242
0.99
0.00
1.0
1.1
—
—
—
0
0
15
149
1.01
0.00
3.3
1.9
—
—
—
0
0
172
1719
1.00
0.00
1.8
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
6.50
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
80.00
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
6.35
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
12.46
—
0
7
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
7
74
0.95
-0.00
12.0
3.4
0.89
0.90
nmol/l
—
7
61
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
137.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.1
32.88
33.71
mg/l
—
5
38
9
94
0.96
-0.00
2.9
3.4
55.00
58.91
%
—
9
94
7
75
0.93
-0.00
3.1
3.4
3.91
4.41
e9/l
—
7
75
0
5
0.00
-0.00
0.0
1.4
—
1.34
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
0.03
—
0
8
9
94
0.96
-0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_MENTPUER – Mental and behavioural disorders associated with the puerperium

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).