No definition available.
Carcinoma in situ of cervix uteri, exocervix
DOID EFO Endpoint Browser PheWeb
CD2_INSITU_CERVIX_UTERI_EXOCERVIX
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
269 |
4. Check minimum number of eventsNone |
269 |
5. Include endpointsNone |
269 |
6. Filter based on genotype QC (FinnGen only) |
253 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D06
- Name in latin
- Carcinoma in situ exocervicis (uteri)
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of cervix uteri, exocervix
based on the number of shared cases.
Similar with more cases:
- HSIL lesion of the cervix uteri
- HSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri
- All dysplastic lesions of the cervix uteri, vagina or vulva
- In situ neoplasms
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 253 | 253 | - |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | - |
| Median age at first event (years) | 35.33 | 35.33 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 259
- Matched controls
- 2590
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
307.7
259
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
36.6
191.4
148
91
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
21.4
141.3
186
276
ULA02
NOMESCO Finland
Kolposcopy
21.0
139.1
187
285
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
669.7
124.0
113
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
22.1
103.1
86
57
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
10.1
74.4
115
189
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
24.4
74.1
56
29
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
133.4
66.7
69
7
LDA10
NOMESCO Finland
Curettage of cervix uteri
10.3
57.6
76
100
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
6.1
45.9
121
325
N87.1
ICD-10 Finland
Moderate cervical dysplasia
10.7
35.8
42
46
ZXC00
NOMESCO Finland
Use of diathermy
46.1
29.9
36
9
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
156.3
27.2
28
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.2
26.8
44
72
LCD10
NOMESCO Finland
Vaginal hysterectomy
6.5
19.9
35
61
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
+∞
16.8
16
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.0
13.2
74
305
C539, 6666, 0
ICD-O-3
11.3
11.5
21
20
N87.0
ICD-10 Finland
Mild cervical dysplasia
4.7
11.1
27
63
G01AA10
ATC
clindamycin; vaginal
2.5
10.7
90
450
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
31.3
9.5
12
*
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
3.8
9.2
30
87
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.7
9.1
30
88
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
+∞
8.4
8
*
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
+∞
8.4
8
*
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
+∞
8.4
8
*
LEB00
NOMESCO Finland
Biopsy of vagina
6.5
7.7
19
31
SPAT1263
SPAT
Sampling
2.0
6.8
116
747
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
71.5
6.5
7
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
+∞
6.3
6
*
8326
FHL
Batch conization
27.4
6.3
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
119
746
2.10
7.79
2.3
1.5
—
—
—
0
0
43
177
2.71
7.40
2.2
1.4
—
—
—
0
0
73
399
2.16
6.67
1.6
1.5
443.02
55978691.97
pmol/l
1.05
58
368
11
23
4.95
3.91
2.8
1.3
—
—
—
0
0
12
29
4.29
3.75
2.7
1.8
17.49
16.32
%
0.79
12
29
102
727
1.66
3.75
3.1
2.7
0.00
0.02
estimate
0.99
39
207
34
185
1.96
3.05
1.5
2.7
0.24
0.22
g/l
0.71
28
180
28
146
2.03
2.83
5.3
3.7
1.23
1.23
mmol/l
0.01
23
132
93
689
1.55
2.75
2.4
2.4
52.60
57.40
u/l
0.70
85
656
12
40
3.10
2.73
2.6
2.5
8.22
8.08
kpa
0.12
12
40
19
91
2.17
2.39
1.3
1.5
12.74
23.93
u/l
1.41
13
76
9
28
3.29
2.33
1.3
1.1
—
—
—
0
0
93
714
1.47
2.25
2.4
3.0
18.84
134.16
ng/l
0.51
41
355
118
949
1.45
2.24
3.6
3.1
0.05
0.03
estimate
0.11
42
213
86
653
1.47
2.19
3.6
3.4
0.00
0.00
estimate
0.50
41
249
35
217
1.71
2.11
3.4
4.6
—
—
—
0
0
237
2210
1.85
2.07
4.0
3.8
1.28
1.22
mmol/l
0.51
222
2100
9
202
0.43
2.06
1.6
1.8
—
—
—
0
0
6
15
4.07
2.05
1.0
1.0
—
—
—
0
0
9
32
2.88
2.02
1.0
1.2
—
—
—
0
0
9
32
2.88
2.02
1.0
1.2
—
—
—
0
0
9
32
2.88
2.02
1.0
1.2
—
—
—
0
0
28
165
1.78
2.01
2.8
2.9
—
—
—
0
0
36
229
1.66
1.98
4.2
3.9
31.29
32.71
%
0.31
24
170
9
193
0.45
1.82
1.6
1.8
—
—
—
0
0
14
67
2.15
1.79
1.1
1.3
—
0.95
—
0
6
29
180
1.69
1.76
2.6
2.1
680.40
3165.65
u/l
—
9
73
81
1008
0.71
1.72
1.9
1.9
1.48
1.37
mmol/l
0.54
66
902
109
898
1.37
1.68
4.6
4.3
36.20
37.08
g/l
1.08
100
866
8
31
2.63
1.67
1.0
1.2
—
—
—
0
0
8
31
2.63
1.67
1.0
1.2
—
—
—
0
0
8
31
2.63
1.67
1.0
1.2
—
—
—
0
0
10
41
2.50
1.66
3.8
2.6
6.38
5.95
pmol/l
—
10
41
240
2275
1.75
1.56
6.3
6.0
1.74
1.75
mu/l
0.06
223
2197
18
101
1.84
1.53
1.1
1.3
—
29.93
—
0
6
143
1250
1.32
1.41
3.9
3.4
0.05
0.01
estimate
0.32
44
246
9
40
2.29
1.41
1.0
1.4
—
—
—
0
0
73
582
1.35
1.35
1.5
1.6
18.91
21.37
nmol/l
1.14
65
513
54
414
1.38
1.27
1.7
1.9
—
—
—
0
0
50
385
1.37
1.15
1.6
1.9
3.34
3.34
ratio
0.00
35
305
194
1796
1.32
1.13
4.5
4.2
10.20
9.36
mm/h
0.38
179
1719
13
73
1.82
1.13
2.2
1.6
—
—
—
0
0
14
81
1.77
1.11
2.1
1.7
—
—
—
0
0
133
1176
1.27
1.11
3.6
4.1
6.02
6.27
mmol/l
0.94
124
1097
70
573
1.30
1.07
2.2
2.2
2.59
2.68
mg/l
0.18
62
503
240
2305
1.56
1.07
12.1
12.4
3.90
3.90
mmol/l
0.08
235
2263
191
1773
1.29
1.03
3.4
3.2
59.02
36.67
u/l
0.68
180
1720
13
76
1.75
1.01
1.1
1.3
—
—
—
0
0
71
589
1.28
0.98
1.2
1.3
1.88
12.46
u/ml
4.03
35
255
0
31
0.00
0.97
0.0
1.1
—
—
—
0
0
6
27
2.25
0.94
1.3
1.2
—
72.20
—
0
5
239
2302
1.50
0.94
12.0
12.3
139.71
139.75
mmol/l
0.10
234
2267
213
2015
1.32
0.94
5.7
5.0
14.30
14.31
pmol/l
0.02
201
1932
16
102
1.61
0.93
1.4
1.5
—
—
—
0
0
25
179
1.44
0.88
1.6
1.5
—
—
—
0
0
6
31
1.96
0.85
1.0
1.4
—
—
—
0
0
136
1232
1.22
0.83
3.9
3.3
0.02
0.00
estimate
0.37
45
254
114
1018
1.21
0.80
5.2
6.1
1.22
1.22
mmol/l
0.03
93
898
65
549
1.25
0.77
1.5
2.4
314.14
296.62
umol/l
0.83
58
511
73
626
1.23
0.76
1.3
1.4
39.67
27.97
iu/ml
0.32
12
208
241
2339
1.44
0.73
4.7
4.5
4.91
4.90
mmol/l
0.07
229
2251
14
205
0.66
0.73
1.3
1.5
1042.74
1030.37
mu/l
—
8
159
44
357
1.28
0.73
2.3
2.4
14.01
14.10
umol/l
0.03
39
332
55
459
1.25
0.73
1.9
2.0
—
—
—
0
0
38
303
1.30
0.72
1.4
1.7
3.71
3.50
mmol/l
0.39
22
219
240
2329
1.42
0.72
4.6
4.4
1.52
1.56
mmol/l
0.78
228
2226
5
26
1.94
0.71
1.0
1.5
—
—
—
0
0
136
1247
1.19
0.69
3.8
3.4
0.00
11.71
estimate
0.80
46
259
5
28
1.80
0.66
1.2
1.0
—
—
—
0
0
66
571
1.21
0.63
3.4
3.8
9.96
6.64
mg/mmol
0.16
38
330
41
337
1.26
0.62
1.9
1.6
1.33
1.30
%
0.18
34
304
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
6
35
1.73
0.58
1.3
1.0
—
—
—
0
0
6
37
1.64
0.56
10.2
3.5
28.50
44.28
u/ml
—
6
37
29
357
0.79
0.54
3.9
3.0
18.83
167.14
ng/l
1.57
12
206
18
135
1.36
0.52
1.3
1.6
—
—
—
0
0
120
1108
1.15
0.52
2.7
2.5
73.34
75.83
nmol/l
0.48
112
1051
10
144
0.68
0.50
1.0
1.2
0.93
0.90
g/l
—
10
144
24
298
0.79
0.49
2.6
2.5
3.13
4.29
e6/l
0.44
12
123
24
297
0.79
0.48
1.7
1.8
—
—
—
0
0
15
112
1.36
0.45
1.1
1.9
—
—
—
0
0
26
316
0.80
0.45
2.6
2.4
0.52
1.15
e6/l
1.85
13
141
116
1078
1.14
0.45
2.2
2.6
—
—
estimate
—
0
0
10
140
0.70
0.44
1.0
1.1
1.50
1.63
g/l
—
10
140
126
1178
1.14
0.44
6.6
5.7
8.94
9.52
umol/l
0.67
121
1131
32
268
1.22
0.43
1.4
1.3
177.85
162.36
u/ml
0.08
13
125
6
91
0.65
0.43
3.7
7.6
0.85
0.63
%
—
6
91
6
92
0.64
0.43
1.8
1.6
—
—
—
0
0
84
766
1.14
0.43
3.7
3.0
2.35
2.35
mmol/l
0.18
84
720
11
150
0.72
0.42
1.2
1.4
—
—
—
0
0
10
70
1.45
0.42
1.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
77
702
1.14
0.39
3.2
2.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.8
—
0.87
—
0
5
240
2355
1.26
0.39
4.9
4.9
2.91
2.90
mmol/l
0.07
228
2254
9
68
1.34
0.38
1.7
1.7
—
—
—
0
0
38
435
0.85
0.37
2.5
2.9
1272.85
510.28
ng/l
0.61
26
362
230
2251
1.19
0.35
12.4
10.8
88.53
89.18
ml/min/173m2
0.23
216
2068
31
265
1.19
0.35
1.9
1.6
1379.12
1149.93
nmol/l
0.64
24
208
228
2230
1.19
0.35
4.7
4.3
5.61
5.67
mmol/l
0.47
218
2126
13
166
0.77
0.34
1.2
1.1
—
—
—
0
0
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
20
236
0.83
0.28
1.6
1.7
—
—
—
0
0
219
2146
1.13
0.26
5.5
5.1
36.68
37.65
mmol/mol
1.82
208
2063
59
543
1.11
0.26
2.5
2.6
0.37
0.30
e6/l
0.10
46
369
182
1770
1.10
0.24
8.9
7.4
73.37
75.41
u/l
0.36
174
1690
7
91
0.76
0.23
1.6
1.5
—
—
—
0
0
7
93
0.75
0.23
3.0
7.6
1.89
1.22
%
—
7
93
26
293
0.87
0.22
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
2.00
—
0
11
0
11
0.00
0.21
0.0
1.2
—
1922.36
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
5.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1277.77
—
0
10
0
12
0.00
0.21
0.0
2.5
—
59.33
—
0
12
0
12
0.00
0.21
0.0
4.0
—
19.07
—
0
12
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
94
895
1.08
0.21
4.2
5.5
1.22
1.22
mmol/l
0.22
81
847
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
—
—
0
0
141
1365
1.07
0.19
3.1
3.4
87.49
70.41
ug/l
1.20
130
1313
7
58
1.21
0.18
1.3
1.5
69.10
54.95
ug/l
—
7
58
57
535
1.08
0.18
1.9
2.0
—
—
—
0
0
19
211
0.89
0.13
2.6
5.3
105.47
104.30
mmol/l
0.63
19
211
143
1397
1.05
0.13
11.1
9.6
3.84
3.85
e9/l
0.02
128
1220
72
691
1.06
0.12
1.5
1.6
—
—
—
0
0
17
153
1.12
0.11
1.6
1.4
—
—
—
0
0
247
2454
1.14
0.11
12.3
10.6
23.85
24.23
u/l
0.18
241
2416
185
1875
0.95
0.10
3.6
3.8
—
—
—
0
0
5
44
1.14
0.10
6.0
2.5
—
—
—
0
0
5
48
1.04
0.09
1.6
1.4
—
—
—
0
0
56
582
0.95
0.09
1.6
1.7
1.01
0.84
mg/l
0.18
44
457
234
2323
1.08
0.08
12.8
12.3
17.93
18.00
mg/l
0.01
192
1829
13
117
1.12
0.08
3.2
2.5
39.31
39.05
u/l
0.02
13
110
6
71
0.84
0.07
1.0
1.1
—
—
—
0
0
6
70
0.85
0.07
1.0
1.1
—
—
—
0
0
9
100
0.90
0.06
1.3
1.9
—
—
—
0
0
83
848
0.97
0.06
3.3
3.2
31.13
28.07
u/l
0.40
77
816
53
546
0.96
0.06
3.6
3.2
1.02
1.02
kg/l
0.42
33
357
64
624
1.03
0.05
2.0
2.0
148.29
100.47
u/l
0.53
59
606
10
90
1.12
0.05
2.1
1.5
—
0.01
—
0
9
17
179
0.95
0.03
4.9
4.4
209.94
251.51
u/l
1.19
17
172
25
259
0.96
0.02
1.7
2.5
3.79
4.91
umol/l
1.34
18
228
90
909
0.98
0.02
1.9
1.9
95.46
98.76
pmol/l
0.34
59
495
72
712
1.02
0.01
1.3
1.3
0.59
1.73
u/ml
1.14
31
212
22
214
1.03
0.00
5.1
3.9
4.68
4.59
pmol/l
0.19
22
192
10
102
0.98
0.00
4.5
5.1
25.80
25.15
mmol/l
—
10
102
10
96
1.04
0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
57.40
—
0
5
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
8.92
—
0
9
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
76.80
—
0
5
0
5
0.00
0.00
0.0
1.2
—
367.60
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
3.4
—
4.64
—
0
9
0
9
0.00
0.00
0.0
3.4
—
11.52
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
62
0.97
-0.00
1.0
1.2
3.50
3.64
mmol/l
—
6
57
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.19
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_CERVIX_UTERI_EXOCERVIX – Carcinoma in situ of cervix uteri, exocervix
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).