HSIL lesion of the cervix uteri

N14_CERVICAL_HSIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D06, N87.1, N87.2
  • Hospital discharge: ICD-9 6221B|6221C|2331A
  • Cause of death: ICD-10 D06, N87.1, N87.2
  • Cause of death: ICD-9 6221B|6221C|2331A

2 out of 7 registries used, show all original rules.

9444

4. Check minimum number of events

None

9444

5. Include endpoints

None

9444

6. Filter based on genotype QC (FinnGen only)

8606

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 53171 53171 -
Only index persons 51989 51989 -
Unadjusted period prevalence (%)
Whole population 1.52 1.52 -
Only index persons 1.91 1.91 -
Median age at first event (years)
Whole population - 34.59 -
Only index persons - 34.40 -

-FinnGen-

Key figures

All Female Male
Number of individuals 8606 8606 -
Unadjusted period prevalence (%) 3.06 3.06 -
Median age at first event (years) 35.37 35.37 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
8995
Matched controls
89950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
83.3
307.7
337
42
N87.1
ICD-10 Finland
Moderate cervical dysplasia
8135.2
307.7
4272
10
8326
FHL
Batch conization
74.4
307.7
295
41
N87.0
ICD-10 Finland
Mild cervical dysplasia
8.0
307.7
1338
1919
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
13.4
307.7
5637
10029
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
+∞
307.7
475
*
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
125.5
307.7
5916
1356
LEB00
NOMESCO Finland
Biopsy of vagina
7.3
307.7
543
784
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
12632.8
307.7
4936
8
ULA02
NOMESCO Finland
Kolposcopy
36.1
307.7
6883
7440
ZXC00
NOMESCO Finland
Use of diathermy
32.2
307.7
418
136
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
23.7
307.7
5175
4871
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
36.3
307.7
6940
7653
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
408.6
307.7
3469
138
A63.0
ICD-10 Finland
Anogenital (venereal) warts
4.6
307.7
1134
2727
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
7.4
307.7
956
1432
C539, 6666, 0
ICD-O-3
180.2
307.7
1203
77
LDA10
NOMESCO Finland
Curettage of cervix uteri
17.3
307.7
2878
2375
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
9.1
298.0
371
424
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
+∞
272.3
260
*
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
13.9
256.2
238
176
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
+∞
242.8
232
*
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
+∞
201.8
193
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
185.5
4747
33375
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
273.7
183.5
187
7
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
70.7
167.7
91
13
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
10.8
167.6
182
172
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
27.0
164.0
112
42
G01AA10
ATC
clindamycin; vaginal
1.9
144.3
2324
13810
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
210.5
140.2
145
7
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
27.8
134.7
91
33
D06.9
ICD-10 Finland
Carcinoma in situ: Cervix, unspecified
1322.2
133.7
130
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.6
126.0
428
1223
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
8.1
116.2
156
195
X86
ICPC
Abnormal cervix smear
4.4
115.9
301
709
C53.11
ICD-10 Finland
Squamous cell carcinoma and exocervix
15.2
111.8
98
65
2331A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Cervix uteri
+∞
106.4
102
*
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
16.4
98.5
83
51
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
13.6
95.4
89
66
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
14.7
89.5
80
55
8070/3-C53.9
ICD-O-3
Squamous cell carcinoma, NOS, of cervix uteri
17.4
84.2
69
40
LCA06
NOMESCO Finland
Biopsy of endometrium
1.8
81.3
1609
9954
N89.0
ICD-10 Finland
Mild vaginal dysplasia
7.1
80.2
120
170
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
8.3
79.0
104
127
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.3
77.6
604
2691
C53.02
ICD-10 Finland
Adenocarcinoma of the endocervix
13.7
68.9
64
47
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
65.4
1812
12164
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
13.9
63.0
58
42
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
62.4
3094
23534
P01AB01
ATC
metronidazole; oral, rectal
1.4
61.9
4030
32284
N87
ICD-10 Finland
Dysplasia of cervix uteri
12.9
61.4
59
46
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
8.8
59.0
74
85
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
9.4
58.0
69
74
N07BA03
ATC
varenicline; oral
2.1
53.8
512
2470
D06BB04
ATC
podophyllotoxin; topical
1.9
52.9
757
4214
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.6
51.4
1472
9895
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
9.1
48.6
59
65
Z3232
NOMESCO Finland
Midwife
1.5
46.8
1554
10776
TLC02
NOMESCO Finland
Simple extraction of IUD
1.8
46.0
730
4190
Z3231
NOMESCO Finland
Registered nurse
1.5
44.7
1968
14443
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
6.8
44.4
69
102
Z2221
NOMESCO Finland
Medical doctor
1.4
42.5
2509
19395
X23
ICPC
Fear sexually transm dis female
1.6
41.8
963
6119
D06BB10
ATC
imiquimod; topical
2.0
40.8
459
2354
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
3.0
39.1
175
592
N90.0
ICD-10 Finland
Mild vulvar dysplasia
5.7
38.2
71
126
8140/2-C53.1
ICD-O-3
Adenocarcinoma in situ, NOS, of exocervix
190.8
36.8
38
*
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
6.9
36.4
56
82
X92
ICPC
Chlamydia infection genital female
2.4
34.3
233
976
R2110
NOMESCO Finland
Giving the first information
1.6
33.4
762
4820
SPAT1193
SPAT
Pap smear
1.4
31.9
1533
11343
8140/2-C53.0
ICD-O-3
Adenocarcinoma in situ, NOS, of endocervix
318.3
31.9
32
*
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.3
31.7
250
1118
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
10.0
30.9
35
35
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
1.9
30.6
366
1916
K05.31
ICD-10 Finland
Periodontitis pronounced
1.7
29.9
617
3800
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
3.4
29.8
107
318
8076/3-C53.9
ICD-O-3
Squamous cell carcinoma, microinvasive of cervix uteri
82.9
29.7
33
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
29.7
6587
60539
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.3
29.5
227
1004
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
29.1
1485
11084
LCH11
NOMESCO Finland
Pharmacologic abortion
1.6
28.7
698
4478
N76.0
ICD-10 Finland
Acute vaginitis
1.5
27.9
1108
7899
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
27.6
2922
24311
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.9
26.7
326
1720
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
26.6
1058
7540
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
3.7
25.2
78
210
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
1.7
25.1
424
2473
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
7.1
25.0
37
52
Z30.4
ICD-10 Finland
Surveillance of contraceptive drugs
1.4
24.4
1097
7989
N93.0
ICD-10 Finland
Postcoital and contact bleeding
2.4
24.0
161
672
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
4.1
23.6
64
157
SPAT1308
SPAT
Sexual health counselling
1.3
23.4
1943
15579
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.5
22.9
727
4947
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
22.4
794
5524
N02AX02
ATC
tramadol; systemic, rectal
1.3
22.3
2851
24123
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
22.2
2717
22873
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
1.8
21.6
356
2063
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
1.8
21.5
350
2019
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
21.4
219
1087
G01AF01
ATC
metronidazole; vaginal
1.4
21.2
838
5955
C539, 8483, 2
ICD-O-3
+∞
20.8
20
*
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
20.7
2337
19450
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
20.3
6826
64040
SPAT1283
SPAT
Restricted health certificate
1.3
20.2
2265
18823
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.2
20.1
168
771
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.3
20.0
1588
12621
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
19.9
425
2639
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
19.7
250
1336
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
4.2
19.7
52
125
J01DB01
ATC
cefalexin; oral
1.3
19.5
7273
68861
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
1.9
19.4
261
1423
W11
ICPC
Contraception oral
1.3
19.3
1372
10726
M03BX02
ATC
tizanidine; oral
1.2
19.3
5601
51502
N02BE01
ATC
paracetamol; systemic, rectal
1.3
19.2
7692
73417
8140/3-C53.9
ICD-O-3
Adenocarcinoma, NOS, of cervix uteri
15.6
19.2
31
20
Z5132
NOMESCO Finland
Nursing associate professional
3.7
18.6
57
153
X85
ICPC
Cervical disease NOS
6.7
17.8
28
42
Z72.0
ICD-10 Finland
Tobacco use
1.9
17.8
209
1090
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
2.5
17.7
113
462
J01CA08
ATC
pivmecillinam; oral
1.2
17.7
4598
41630
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
5.2
17.5
35
67
M54.5
ICD-10 Finland
Low back pain
1.2
17.2
3269
28675
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.6
16.8
350
2163
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.6
16.7
349
2158
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
16.4
4822
44037
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.3
16.3
1359
10842
LCD10
NOMESCO Finland
Vaginal hysterectomy
1.7
15.5
261
1523
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.3
15.2
941
7193
PJA01
NOMESCO Finland
Laparoscopic sentinel node excision
3.7
14.9
47
129
X15
ICPC
Vaginal symptom/complaint other
1.4
14.9
562
3955
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
14.8
3371
29955
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
14.7
3441
30657
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
14.6
628
4524
EBA00
NOMESCO Finland
Extraction of tooth
1.2
14.2
2829
24799
K02.1
ICD-10 Finland
Caries of dentine
1.2
14.2
5503
51187
C53.12
ICD-10 Finland
Adenocarcinoma of the exocervix
11.9
14.0
25
21
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
6.7
14.0
22
33
F17.2
ICD-10 Finland
Mental and behavioural disorders due to use of tobacco, dependence syndrome
2.5
14.0
89
365
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
13.8
2575
22423
R87.3
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of substances chiefly nonmedicinal as to source
17.5
13.8
21
12
N06AX11
ATC
mirtazapine; oral
1.2
13.8
2703
23648
X14
ICPC
Vaginal discharge
1.6
13.7
354
2304
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
13.7
8289
80585
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.2
13.5
2594
22643
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
3.1
13.4
56
184
W14
ICPC
Contraception female other
1.4
13.4
761
5744
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.3
13.1
1171
9410
P17
ICPC
Tobacco abuse
2.1
13.1
125
608
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.5
13.0
376
2511
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.5
13.0
415
2829
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.3
12.8
755
5726
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.5
12.7
439
3039
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
12.7
3288
29441
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
12.6
4100
37397
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
12.5
1961
16764
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
12.3
2862
25374
O04.6
ICD-10 Finland
Medical abortion, complete or unspecified, complicated by delayed or excessive haemorrhage
1.9
12.2
151
804
SDE04
NOMESCO Finland
Periodontal treatment by dental hygienist, very extensive
1.4
12.2
662
4959
Z87.4
ICD-10 Finland
Personal history of diseases of the genitourinary system
2.2
12.1
101
466
SPAT1192
SPAT
Gynaecological examination
1.2
12.1
1440
11957
N05CF01
ATC
zopiclone; oral
1.2
11.9
1956
16788
1390
FHL
Colposcopy
4.6
11.6
27
59
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.2
11.6
1301
10732
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
2.0
11.5
125
638
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
11.5
2040
17629
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
11.5
1646
13931
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
4.3
11.5
29
68
8077/2-C53.0
ICD-O-3
Squamous intraepithelial neoplasia, high grade of endocervix
120.2
11.4
12
*
WX290
NOMESCO Finland
Other blockage of nerve
1.2
11.4
4663
43180
J02AC01
ATC
fluconazole; systemic
1.2
11.3
4356
40144
SPAT1263
SPAT
Sampling
1.2
11.2
3308
29841
T74.1
ICD-10 Finland
Physical abuse
1.7
11.2
187
1091
LCH13
NOMESCO Finland
Vacuum aspiration from uterus after medically induced abortion
1.7
11.2
222
1357
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
3.3
11.2
41
125
LDA96
NOMESCO Finland
Other biopsy of cervix uteri
17.0
11.2
17
10
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.3
11.2
932
7418
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.5
11.1
300
1973
SFA30
NOMESCO Finland
Three-surface restoration
1.2
11.0
3184
28677
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
3.8
10.9
32
84
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
10.8
113
569
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
2.2
10.8
83
371
A03
ICPC
Fever
1.2
10.6
1684
14385
SPAT1312
SPAT
General health counselling
1.2
10.6
2481
21941
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.5
10.5
301
2006
XLA10, ,
NOMESCO Finland
1.4
10.5
430
3073
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
10.5
3354
30404
SFA10
NOMESCO Finland
One-surface restoration
1.2
10.5
4882
45518
D82
ICPC
Teeth/gum disease
1.2
10.4
3498
31822
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
10.4
6402
60951
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
10.4
3385
30722
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.2
10.4
1733
14870
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
10.3
2053
17902
C53.00
ICD-10 Finland
Malignant tumor of endocervix without histology
9.5
10.2
20
21
Z30.8
ICD-10 Finland
Other contraceptive management
1.4
10.2
379
2661
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
10.1
6109
57992
J05AB01
ATC
aciclovir; systemic
1.2
10.0
1782
15379
M01AB05
ATC
diclofenac; systemic, rectal
1.2
10.0
5290
49699
SDA03
NOMESCO Finland
Periodontal treatment
1.2
10.0
3708
33954
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
0.7
9.9
512
6796
R74
ICPC
Upper respiratory infection acute
1.2
9.9
3757
34456
X29
ICPC
Genital sympt/compl female other
1.7
9.8
170
1005
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
9.8
93
453
8327
FHL
Amputation portionis and conization
26.0
9.8
13
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.2
9.7
1479
12572
C53.0
ICD-10 Finland
Malignant neoplasm: Endocervix
13.4
9.6
16
12
4044, ,
NOMESCO Finland
5.3
9.6
19
36
M01AH05
ATC
etoricoxib; oral
1.2
9.6
5158
48437
P01
ICPC
Feeling anxious/nervous/tense
1.2
9.6
1597
13691
SFA20
NOMESCO Finland
Two-surface restoration
1.2
9.6
5318
50055
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
2.9
9.6
44
154
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.6
9.5
217
1378
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
9.4
1631
14028
J01AA02
ATC
doxycycline; systemic
1.2
9.4
6264
59695
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
9.4
5676
53702
8010/2-C53.9
ICD-O-3
Carcinoma in situ, NOS, of cervix uteri
100.2
9.4
10
*
Z71.8
ICD-10 Finland
Other specified counselling
1.2
9.4
3104
28141
N97.2
ICD-10 Finland
Female infertility of uterine origin
3.9
9.4
27
70
D06.7
ICD-10 Finland
Carcinoma in situ: Other parts of cervix
+∞
9.4
9
*
Z30.2
ICD-10 Finland
Sterilization
1.2
9.3
1034
8504
8070/3-C53.1
ICD-O-3
Squamous cell carcinoma, NOS, of exocervix
12.3
9.3
16
13
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
9.3
195
1212
M54
ICD-10 Finland
Dorsalgia
1.2
9.2
1127
9367
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
7.3
9.2
21
29
LDA00
NOMESCO Finland
Dilatation of cervix uteri
2.1
9.2
84
404
ZXE00
NOMESCO Finland
One hour or less
1.2
9.2
3023
27395
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.3
9.0
607
4698
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
1.5
8.9
226
1472
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
8.8
1579
13616
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
2.0
8.8
86
424
N05BA04
ATC
oxazepam; oral
1.2
8.8
2041
17994
SDA05
NOMESCO Finland
Very demanding periodontal treatment
1.3
8.8
564
4335
F43.0
ICD-10 Finland
Acute stress reaction
1.3
8.8
756
6040
WF002
NOMESCO Finland
Radical radiotherapy
1.7
8.7
153
909
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.2
8.7
1242
10484
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
1.7
8.7
148
872
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.3
8.7
866
7038
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
8.7
519
3947
X91
ICPC
Condylomata acuminata female
2.7
8.7
46
174
LX1A3, ,
SPAT
3.0
8.7
36
119
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
1.9
8.6
104
552
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
8.6
2498
22398
LDC10
NOMESCO Finland
Partial excision of cervix uteri
9.0
8.5
17
19
N06AX16
ATC
venlafaxine; oral
1.2
8.5
1314
11180
ULC02
NOMESCO Finland
Hysteroscopy
1.4
8.5
451
3371
AA1AD
NOMESCO Finland
CT of head and brain
1.2
8.5
1265
10725
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2.2
8.4
68
312
N07BB01
ATC
disulfiram; oral
1.6
8.4
204
1315
J01DA01
ATC
[U] cefalexin
1.1
8.4
5019
47266
T810, N872,
ICD-10 Finland
+∞
8.3
8
*
D11
ICPC
Diarrhoea
1.2
8.3
1144
9625
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.2
8.2
1105
9273
R87
ICD-10 Finland
Abnormal findings in specimens from female genital organs
3.1
8.2
32
102
LCD30
NOMESCO Finland
Radical hysterectomy
4.2
8.2
21
50
F51.0
ICD-10 Finland
Nonorganic insomnia
1.2
8.2
1800
15792
M77.1
ICD-10 Finland
Lateral epicondylitis
1.3
8.1
762
6149
J01FA10
ATC
azithromycin; systemic
1.1
8.0
5289
50052
OAA64, ,
SPAT
1.3
8.0
539
4171
ZX040
NOMESCO Finland
Intracavity HDR radiotherapy
3.8
8.0
23
60
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
1.8
7.9
106
583
M79.6
ICD-10 Finland
Pain in limb
1.1
7.9
3620
33454
WX002
NOMESCO Finland
Sedation and analgesia
1.2
7.9
961
7982
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.2
7.8
1878
16578
N06AB04
ATC
citalopram; systemic
1.2
7.8
1541
13388
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.2
7.8
933
7736
L03
ICPC
Low back symptom/complaint
1.2
7.8
2448
22050
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.2
7.7
1242
10597
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.2
7.7
1000
8359
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.1
7.7
3231
29674
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
1.4
7.7
326
2350
H02AB06
ATC
prednisolone; systemic
1.1
7.7
3386
31196
Z72.1
ICD-10 Finland
Alcohol use
2.2
7.7
62
285
J36
ICD-10 Finland
Peritonsillar abscess
1.4
7.7
285
2007
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
1.4
7.7
344
2504
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
7.7
1114
13097
M01AE02
ATC
naproxen; oral, rectal
1.1
7.6
4866
45874
XQ900
NOMESCO Finland
Photography of physically assaulted person
18.4
7.6
11
6
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
7.6
1587
13859
J01FF01
ATC
clindamycin; systemic
1.2
7.5
1837
16236
W12
ICPC
Contraception intrauterine
1.2
7.5
1566
13668
Z01.2
ICD-10 Finland
Dental examination
1.1
7.5
4248
39740
N93.8
ICD-10 Finland
Other specified abnormal uterine and vaginal bleeding
1.5
7.5
193
1264
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
7.4
1436
12455
J01MA02
ATC
ciprofloxacin; systemic
1.1
7.4
2299
20681
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
2.0
7.4
77
391
R51.80
ICD-10 Finland
Headache
1.2
7.3
1501
13080
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.1
7.3
4425
41537
M01AE03
ATC
ketoprofen; systemic, rectal
1.1
7.3
2264
20359
ZXC96
NOMESCO Finland
Robot assisted procedure
2.0
7.3
73
365
X84
ICPC
Vaginitis/vulvitis NOS
1.8
7.3
104
585
R42
ICD-10 Finland
Dizziness and giddiness
1.2
7.3
1387
12015
LDC96
NOMESCO Finland
Other excision of cervix uteri
15.7
7.2
11
7
D01
ICPC
Abdominal pain/cramps general
1.2
7.2
1064
9008
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
1.5
7.2
181
1180
L04AX01
ATC
azathioprine; systemic
1.4
7.1
275
1953
Z30
ICD-10 Finland
Contraceptive management
1.4
7.0
316
2301
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
7.0
1716
15156
N05AH04
ATC
quetiapine; oral
1.2
7.0
1448
12619
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.4
7.0
251
1756
P19
ICPC
Drug abuse
2.0
7.0
68
336
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.2
6.9
1105
9423
LDD00
NOMESCO Finland
Suture of cervix uteri
5.4
6.9
19
35
D19
ICPC
Teeth/gum symptom/complaint
1.1
6.9
2774
25369
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
1.4
6.8
280
2008
C539, 8085, 3
ICD-O-3
8.2
6.8
14
17
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.1
6.8
3794
35386
SPAT1254
SPAT
Administration of medicine
1.2
6.7
694
5663
TLE30
NOMESCO Finland
Tamponation of vagina
3.9
6.7
19
49
P74
ICPC
Anxiety disorder/anxiety state
1.3
6.7
484
3785
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.3
6.7
538
4265
WZA90
NOMESCO Finland
Other medical or dental certificate
1.2
6.7
1736
15401
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.3
6.7
599
4812
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.1
6.7
2024
18158
SAE03, ,
NOMESCO Finland
2.7
6.6
34
127
P01BA02
ATC
hydroxychloroquine; oral
1.3
6.6
549
4368
O47.9
ICD-10 Finland
False labour, unspecified
1.4
6.6
231
1612
M03BC51
ATC
orphenadrine, combinations; systemic
1.1
6.6
2115
19047
8140/3-C53.0
ICD-O-3
Adenocarcinoma, NOS, of endocervix
10.0
6.5
12
12
H00.00
ICD-10 Finland
Hordeolum
1.3
6.5
380
2885
LWE00
NOMESCO Finland
Reoperation for deep haemorrhage in gynaecological surgery
2.6
6.5
36
140
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.3
6.5
611
4938
Z2446
NOMESCO Finland
Social worker
1.3
6.5
393
3002
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.2
6.4
652
5312
JN3AD
NOMESCO Finland
Abdominal CT examination
1.2
6.4
692
5675
D06
ICPC
Abdominal pain localized other
1.2
6.4
755
6254
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.2
6.4
1101
9453
F90.0
ICD-10 Finland
Disturbance of activity and attention
1.3
6.3
424
3282
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.3
6.3
566
4550
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
0.6
6.3
134
2082
8070/2-C53.1
ICD-O-3
Squamous cell carcinoma in situ, NOS, of exocervix
+∞
6.2
6
*
N30.0
ICD-10 Finland
Acute cystitis
1.2
6.2
1506
13281
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.2
6.2
1547
13671
SGC10
NOMESCO Finland
Pulp capping
1.2
6.2
776
6463
LCD11
NOMESCO Finland
Laparoscopically assisted vaginal hysterectomy
1.9
6.2
71
374
N05CF02
ATC
zolpidem; oral
1.2
6.2
1289
11242
W60
ICPC
Pregnancy, Result test/procedure
2.0
6.2
60
298
SPAT1249
SPAT
Treatment-related counselling outside office
1.1
6.1
3179
29468
SPAT1301
SPAT
No procedures
1.1
6.1
1998
17997
8112
FHL
Scraping the cervix
5.7
6.1
16
28
TAC99
NOMESCO Finland
Other blockade for chronic pain
2.4
6.1
40
169
R21
ICPC
Throat symptom/complaint
1.1
6.1
2347
21371
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
0.8
6.1
556
6852
F10.09
ICD-10 Finland
Alcohol intoxication UNS
1.7
6.0
104
619

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5383
34829
2.36
307.65
2.6
2.0
—
—
—
0
0
1934
2514
9.53
307.65
2.5
1.6
—
—
—
0
0
1046
5482
2.03
89.46
1.4
1.4
—
—
—
0
0
87
170
5.16
42.10
1.7
2.2
6.56
4.12
ug/l
0.19
59
102
3457
30125
1.24
20.37
2.3
2.1
—
—
—
0
0
1402
10965
1.33
19.73
1.3
1.2
—
—
—
0
0
6078
56967
1.21
14.77
4.5
4.2
3.94
11.48
—
8
55
4943
45476
1.19
14.70
3.7
3.5
0.01
0.13
estimate
0.55
1008
9294
4905
45205
1.19
13.94
3.7
3.5
9.03
3.99
estimate
0.82
1059
9497
5869
55030
1.19
13.37
4.4
4.1
1784.42
1976.09
e6/l
0.06
59
587
4849
44800
1.18
12.89
3.7
3.5
0.00
0.00
estimate
0.31
1035
9440
233
1415
1.66
12.04
1.6
1.5
1.60
5.27
titre
—
5
15
6026
56895
1.18
11.65
7.6
7.3
71.21
72.56
u/l
2.33
5741
54345
8262
80545
1.32
11.16
12.7
11.7
19.29
18.62
mg/l
1.13
6715
64722
2993
26851
1.17
10.78
2.2
2.0
—
—
—
0
0
3122
28171
1.17
10.33
3.7
3.5
53.98
71.19
e6/l
1.42
2015
18221
595
4529
1.34
9.87
3.7
2.5
—
—
—
0
0
2163
19021
1.18
9.75
3.0
2.8
0.29
0.29
e6/l
0.01
1524
13374
1230
10276
1.23
9.61
2.3
2.3
4916.92
6313.08
u/l
0.91
498
4278
3917
36118
1.15
9.36
3.2
3.1
6.25
6.23
ph
0.74
2215
20807
1350
11475
1.21
8.82
2.6
2.5
0.93
1.11
e6/l
1.01
659
5682
718
5705
1.28
8.69
2.7
1.9
—
—
—
0
0
2471
22135
1.16
8.64
3.1
2.9
44.13
62.53
e6/l
0.71
1821
16316
7907
76991
1.22
8.63
11.9
11.2
139.52
139.57
mmol/l
1.34
7749
75452
7917
77113
1.22
8.53
12.1
11.3
3.90
3.89
mmol/l
0.72
7746
75391
1663
14448
1.19
8.51
1.7
1.6
—
—
—
0
0
4096
38065
1.14
8.37
6.7
6.3
0.69
0.69
%
0.30
3852
35884
885
7243
1.25
8.34
1.8
1.9
0.04
0.05
estimate
0.11
196
1709
1244
10547
1.21
8.33
2.7
2.6
4.92
4.99
e6/l
0.05
549
4739
4476
41858
1.14
8.27
6.5
6.2
0.04
0.04
e9/l
0.00
3967
37066
768
6192
1.26
8.25
2.6
1.9
—
—
—
0
0
2442
21937
1.16
8.13
1.8
1.8
—
—
—
0
0
2217
19776
1.16
8.11
2.2
2.0
—
—
—
0
0
767
6212
1.26
7.93
2.3
1.9
—
—
—
0
0
476
3625
1.33
7.91
1.9
1.6
0.27
0.28
mg/l
0.12
224
1427
769
6232
1.26
7.91
2.6
1.9
—
—
—
0
0
4464
41812
1.13
7.89
6.5
6.2
0.53
0.52
e9/l
0.69
3959
37089
4337
40592
1.13
7.66
2.7
2.6
—
—
estimate
—
0
0
4089
38132
1.13
7.66
6.6
6.2
2.69
2.76
%
1.58
3853
36062
4092
38186
1.13
7.53
6.8
6.3
8.09
8.11
%
0.15
3868
36179
4031
37591
1.13
7.48
5.7
5.6
9.09
9.57
umol/l
3.76
3808
35675
359
2642
1.37
7.48
3.3
2.4
—
—
—
0
0
2606
23631
1.14
7.47
3.8
3.6
0.00
0.00
estimate
0.53
1020
9136
755
6158
1.25
7.34
2.5
1.8
—
—
—
0
0
4564
42980
1.13
7.03
6.5
6.2
1.98
1.97
e9/l
0.43
4140
39002
4898
46330
1.13
6.99
8.9
8.9
4.01
3.96
e9/l
0.85
4314
40877
4599
43351
1.12
6.93
6.7
6.3
0.18
0.18
e9/l
0.17
4148
39045
4224
39644
1.12
6.80
6.6
6.1
29.64
29.76
%
0.34
4035
37911
6294
60509
1.13
6.72
3.2
3.0
33.74
32.83
u/l
0.46
6045
58339
2066
18564
1.15
6.64
1.3
1.3
9.50
8.17
u/ml
0.47
838
8066
2204
19894
1.14
6.62
3.5
3.5
0.25
0.26
—
8
133
2226
20170
1.14
6.26
1.4
1.4
40.55
26.23
iu/ml
0.46
660
5967
4152
39068
1.12
6.15
6.4
6.0
56.48
56.45
%
0.07
3995
37583
3868
36263
1.12
6.10
10.0
9.5
0.00
0.00
e9/l
4.90
3179
29653
2835
26160
1.12
5.85
1.8
1.8
—
—
—
0
0
1435
12671
1.16
5.83
2.8
2.6
516.66
512.70
mosm/kgh2o
0.26
1246
11054
3491
32636
1.11
5.66
6.2
5.8
1.22
1.22
mmol/l
0.79
3039
28487
83
476
1.75
5.53
1.3
1.1
—
—
—
0
0
836
7098
1.20
5.48
2.3
2.8
46.94
39.28
u/ml
0.19
812
6871
3237
30178
1.11
5.47
4.6
4.4
37.10
37.09
g/l
0.02
3072
28558
2790
25810
1.12
5.42
6.9
7.2
1.08
1.08
inr
0.16
2271
21230
1681
15085
1.14
5.39
2.6
2.5
9.94
8.53
e6/l
1.06
1504
13571
8452
83329
1.24
5.37
14.0
13.2
66.41
66.01
umol/l
0.93
8375
82555
2003
18183
1.13
5.36
3.8
3.5
97.47
98.14
%
0.69
1944
17677
460
3688
1.26
5.26
1.9
1.9
0.01
0.04
estimate
2.26
170
1425
86
513
1.68
5.02
4.5
2.4
—
—
—
0
0
2822
26292
1.11
4.65
2.7
2.7
0.07
0.03
0.21
30
338
7953
78118
1.16
4.58
5.9
5.9
1.66
1.72
mu/l
5.62
7620
75244
94
590
1.60
4.54
1.6
1.6
1.51
1.13
promille
1.90
72
457
3679
34766
1.10
4.50
3.5
3.3
0.04
0.12
estimate
0.63
871
7904
7220
70499
1.12
4.48
5.0
5.0
14.29
14.27
pmol/l
0.33
6865
67273
7502
73427
1.13
4.45
3.9
3.9
5.54
5.58
mmol/l
1.86
7120
69900
1325
11852
1.14
4.42
1.3
1.3
23.33
24.47
iu/l
0.69
1138
10351
663
5641
1.19
4.29
1.3
1.2
—
—
—
0
0
819
7095
1.17
4.27
1.8
1.9
—
—
—
0
0
3056
28699
1.10
4.19
5.8
5.3
1.21
1.22
mmol/l
1.06
2845
26882
8462
83615
1.20
4.11
10.7
10.0
23.61
23.80
u/l
0.31
8303
81977
1612
14682
1.12
3.99
1.4
1.4
541.29
545.79
titre
0.03
340
3087
601
5110
1.19
3.94
1.4
1.3
—
—
—
0
0
2537
23703
1.10
3.81
2.5
2.6
53.63
58.93
u/l
3.75
2363
22186
1081
9653
1.14
3.70
1.5
1.5
—
—
—
0
0
5142
49575
1.09
3.70
3.0
3.0
0.57
43.32
—
7
56
825
7235
1.15
3.68
3.8
3.3
—
—
—
0
0
2042
18922
1.10
3.62
1.9
2.0
193.92
134.76
u/l
1.22
1957
18121
1034
9223
1.14
3.61
1.6
1.7
—
—
—
0
0
2426
22701
1.09
3.48
2.7
2.6
27.42
62.38
ng/l
0.53
993
9679
1624
14910
1.11
3.45
4.0
3.7
—
—
—
0
0
971
8679
1.13
3.29
1.4
1.4
—
—
—
0
0
2643
24879
1.09
3.28
3.1
3.2
2.35
2.35
mmol/l
0.07
2466
23180
16
61
2.63
3.13
10.2
10.2
5.11
5.11
mmol/l
0.00
16
61
1972
18366
1.09
3.10
1.6
1.6
20.44
20.65
nmol/l
0.29
1727
16424
8862
88159
1.35
3.04
19.5
18.3
30.26
30.03
pg
32.52
8818
87702
8860
88138
1.35
3.02
19.7
18.4
269.83
269.86
e9/l
0.02
8756
87062
8862
88161
1.35
3.02
19.5
18.3
90.81
90.24
fl
31.43
8817
87702
219
1731
1.27
2.98
1.9
2.1
2.87
2.79
g/l
0.65
202
1622
8862
88165
1.35
2.98
19.9
18.6
40.31
40.33
%
0.02
8816
87671
3153
29986
1.08
2.98
1.9
1.9
100.14
99.20
pmol/l
0.54
1754
16453
274
2224
1.24
2.97
2.3
2.0
1.39
1.35
g/l
0.27
240
1949
8863
88180
1.35
2.94
19.7
18.5
6.80
6.69
e9/l
5.02
8753
86945
8862
88169
1.35
2.94
19.6
18.4
4.42
4.46
e12/l
15.81
8753
86967
2122
19884
1.09
2.89
3.5
3.5
1.02
1.17
kg/l
0.80
1369
12720
777
6913
1.14
2.86
2.3
2.3
6.14
6.20
ph
1.10
461
4211
1577
14593
1.10
2.84
2.6
2.5
103.38
97.84
ug/g
0.30
1238
11528
2701
25582
1.08
2.81
1.3
1.4
1.43
1.40
u/ml
0.05
817
7827
1384
12737
1.10
2.79
2.3
2.4
2.42
2.42
mmol/l
0.03
1232
11406
224
1792
1.26
2.79
1.9
2.1
3.68
3.63
g/l
0.24
207
1685
224
1793
1.26
2.77
1.9
2.1
4.30
4.31
g/l
0.06
207
1683
224
1795
1.25
2.75
1.9
2.1
7.30
7.20
g/l
0.44
207
1685
156
1194
1.31
2.75
2.5
3.3
32.92
40.18
mg/l
0.75
132
1021
38
217
1.75
2.75
2.8
2.7
0.59
0.61
mmol/l
1.31
38
217
8862
88189
1.33
2.75
19.7
18.5
133.08
133.13
g/l
0.18
8818
87731
636
5600
1.15
2.74
3.0
3.3
7.35
7.35
ph
0.15
431
3979
178
1389
1.29
2.72
1.3
1.2
17.31
12.83
u/ml
0.14
13
67
6
10
6.00
2.69
1.0
1.0
—
—
—
0
0
155
1194
1.30
2.62
2.5
3.3
26.44
35.04
mg/l
1.46
131
1021
610
5379
1.14
2.59
7.8
7.3
13.15
13.93
kpa
3.10
580
5172
609
5381
1.14
2.52
7.8
7.3
5.08
5.02
kpa
1.00
581
5182
842
7594
1.12
2.50
3.3
3.7
33.04
32.67
%
0.46
652
5755
319
2682
1.20
2.49
10.5
9.3
24.30
24.16
mmol/l
0.30
310
2631
974
8863
1.11
2.47
3.0
2.4
5.61
6.15
umol/l
0.64
803
7475
1046
9558
1.11
2.45
1.9
1.8
—
—
—
0
0
2226
21026
1.08
2.45
2.2
2.2
2.51
2.56
mg/l
0.56
1921
18458
58
382
1.52
2.44
2.6
2.5
201.29
164.83
au/ml
—
7
68
1171
10769
1.10
2.41
2.8
2.9
4.37
4.24
e9/l
0.31
1039
9735
695
6214
1.13
2.40
4.5
4.3
0.75
0.67
%
0.14
180
1496
609
5400
1.14
2.40
8.0
7.4
7.42
7.42
ph
0.48
308
2899
2264
21419
1.08
2.38
1.4
1.4
2.14
2.11
g/l
0.34
1452
14258
372
3186
1.17
2.36
1.4
1.4
21.11
23.96
u/l
1.05
278
2631
112
838
1.34
2.36
3.2
2.8
1.29
1.48
%
0.30
99
766
2961
28289
1.07
2.35
3.4
3.1
29.01
29.19
u/l
0.05
2822
27062
2087
19701
1.08
2.32
4.2
3.7
7.40
7.40
ph
0.26
1487
13623
601
5340
1.13
2.31
7.8
7.3
0.81
0.67
mmol/l
0.36
477
4261
2789
26621
1.07
2.26
3.1
2.8
0.02
0.07
estimate
0.75
878
7892
191
1542
1.24
2.26
1.9
2.0
10.51
10.11
g/l
0.66
172
1423
807
7314
1.11
2.22
2.5
2.4
34.39
36.10
u/l
0.32
682
6187
522
4609
1.14
2.22
8.2
7.8
96.13
96.41
%
0.43
500
4435
104
780
1.34
2.18
1.6
1.5
55.19
66.30
mmol/l
1.91
88
616
42
651
0.64
2.18
1.2
1.5
0.50
0.50
e9/l
0.02
42
651
15
67
2.24
2.17
13.5
4.9
—
—
—
0
0
2442
23237
1.07
2.16
5.6
5.7
—
—
—
0
0
370
3197
1.16
2.14
2.7
2.1
0.23
0.23
g/l
0.27
349
3074
719
6491
1.12
2.14
4.7
4.4
0.79
0.86
%
0.19
187
1539
1176
10883
1.09
2.13
3.0
2.9
244.44
272.50
ng/l
0.19
603
5565
711
6416
1.12
2.13
1.3
1.3
27.33
41.63
au/ml
2.28
38
359
53
355
1.50
2.11
1.9
1.9
—
—
—
0
0
316
2700
1.18
2.10
8.8
8.9
15.94
16.08
%
0.38
305
2584
12
49
2.45
2.10
1.0
1.6
—
—
—
0
0
61
421
1.45
2.09
3.3
3.2
10.81
8.54
mg/l
0.90
47
333
938
8604
1.10
2.06
1.2
1.2
—
—
—
0
0
458
5188
0.88
2.04
1.5
1.5
59.14
59.69
ug/l
0.09
458
5188
758
6885
1.11
2.03
2.4
2.4
16.08
19.76
au/ml
1.52
107
980
40
254
1.58
2.02
28.1
27.2
114.94
111.17
ug/l
0.15
34
205
693
6266
1.11
2.02
4.7
4.5
0.08
0.13
%
1.11
163
1313
52
352
1.48
1.98
1.1
1.1
1.90
2.30
u/ml
0.10
31
209
357
3097
1.16
1.98
1.3
1.4
6.59
9.09
u/ml
0.69
62
445
90
672
1.34
1.98
1.3
1.3
37.00
57.27
u/ml
—
7
48
366
3182
1.16
1.97
2.8
2.7
1.02
1.02
ratio
0.24
308
2750
32
194
1.65
1.95
4.3
5.1
—
—
—
0
0
356
3092
1.16
1.95
1.9
2.1
6.78
5.34
ug/l
0.28
317
2706
290
2479
1.18
1.95
1.3
1.3
3.13
2.67
u/ml
0.13
27
163
132
1042
1.27
1.94
2.5
3.1
1.82
2.40
ratio
0.35
66
568
504
4485
1.13
1.94
8.7
8.1
119.63
120.58
g/l
0.52
492
4373
38
242
1.57
1.92
3.3
4.0
4399.17
2993.71
mg/l
0.12
30
178
46
307
1.50
1.89
2.3
2.2
30.65
28.41
%
0.42
46
307
376
3288
1.15
1.89
2.7
2.1
1.16
1.18
g/l
0.68
357
3171
0
53
0.00
1.86
0.0
1.5
—
31.90
—
0
40
7261
71619
1.07
1.86
15.1
14.2
13.34
13.33
%
0.20
7176
70778
355
3099
1.15
1.83
1.4
1.4
13.62
6.14
u/ml
0.82
45
288
440
3898
1.14
1.83
1.3
1.2
—
—
—
0
0
256
2179
1.18
1.83
2.7
2.2
10.77
10.51
mg/l
0.23
247
2072
639
5790
1.11
1.81
2.4
2.3
0.23
0.23
g/l
1.42
595
5490
383
3368
1.14
1.79
1.3
1.3
34.07
36.76
u/ml
0.10
24
213
11
47
2.34
1.77
2.0
1.5
322.35
517.20
nmol/l
1.06
11
47
504
4521
1.12
1.73
2.8
2.1
11.19
7.23
iu/ml
1.30
134
1093
85
645
1.32
1.72
2.4
2.5
23.00
24.40
mg/l
0.16
61
451
0
46
0.00
1.70
0.0
1.7
—
13.47
—
0
40
204
1715
1.19
1.70
3.0
3.5
191.73
303.00
u/ml
0.43
174
1479
347
3044
1.15
1.70
1.4
1.3
—
—
—
0
0
652
5945
1.10
1.66
1.4
1.4
208.59
233.25
miu/ml
1.21
326
3063
3130
30218
1.05
1.66
1.8
1.8
—
—
—
0
0
54
384
1.41
1.64
2.5
2.9
40.90
46.74
%
1.08
23
237
7152
70586
1.06
1.64
4.5
4.6
36.44
36.94
mmol/mol
7.86
6830
67842
227
1935
1.18
1.63
3.6
2.9
1.38
1.27
mg/l
1.24
217
1817
1015
9452
1.08
1.63
1.4
1.4
—
—
—
0
0
242
2078
1.17
1.60
1.2
1.2
—
—
—
0
0
127
1026
1.24
1.59
1.0
1.1
—
—
—
0
0
47
328
1.44
1.59
2.2
1.9
57.47
23.00
ug/l
0.65
47
322
6
20
3.00
1.58
1.0
1.2
175.63
211.24
nmol/l
—
6
20
254
2192
1.16
1.58
1.5
1.6
383.18
389.98
mu/l
0.07
191
1776
72
542
1.33
1.57
2.8
2.8
13.40
14.38
index
0.46
43
333
973
9071
1.08
1.53
1.7
1.7
1151.27
1190.49
nmol/l
0.71
774
7236
478
4312
1.11
1.52
10.4
8.3
—
—
—
0
0
138
1674
0.82
1.52
1.1
1.1
115.65
118.34
%
0.47
126
1546
5306
51999
1.05
1.50
3.3
3.4
71.53
66.98
ug/l
1.45
5051
49967
71
538
1.32
1.49
3.5
2.8
55.16
55.45
%
0.04
62
465
12
58
2.07
1.49
1.0
1.6
—
—
—
0
0
576
5258
1.10
1.47
3.4
3.9
5.77
21.19
ug/l
1.38
430
3774
4292
41864
1.05
1.47
4.4
4.2
6.17
6.25
mmol/l
2.23
3902
38112
700
6454
1.09
1.44
5.0
4.7
0.11
0.30
%
0.71
157
1290
309
2730
1.14
1.41
1.6
1.6
5.80
11.89
iu/ml
—
8
72
492
4470
1.11
1.39
1.3
1.3
1.34
1.05
u/ml
0.15
32
322
371
3319
1.12
1.39
1.4
1.5
81.16
97.85
pmol/l
0.52
365
3240
903
9662
0.93
1.38
1.5
1.5
—
—
—
0
0
123
1009
1.22
1.38
3.6
3.0
31.56
32.80
umol/l
0.35
117
938
38
263
1.45
1.38
1.1
1.1
—
—
—
0
0
52
381
1.37
1.38
2.3
2.3
120.62
166.70
umol/l
0.80
34
184
312
2766
1.13
1.36
2.5
2.4
3.64
3.60
g/l
0.15
287
2625
702
6496
1.09
1.35
2.8
2.7
10.49
10.48
g/l
0.04
656
6034
0
37
0.00
1.34
0.0
1.5
—
0.94
—
0
31
0
37
0.00
1.34
0.0
1.0
—
0.05
—
0
25
60
452
1.33
1.34
3.0
2.7
130.27
230.45
e6/l
0.95
60
446
432
3909
1.11
1.33
2.2
2.4
67.05
67.31
g/l
0.32
399
3654
509
4650
1.10
1.31
4.4
3.7
1.95
1.70
mmol/l
0.92
449
4058
34
235
1.45
1.26
2.6
3.0
105.55
92.70
ng/l
0.08
15
125
525
4814
1.10
1.26
4.4
3.6
5.87
5.81
kpa
0.71
514
4676
6
25
2.40
1.24
4.0
2.1
—
—
—
0
0
2141
20611
1.05
1.24
3.5
3.3
7.46
7.52
mmol/l
0.25
1891
18177
47
348
1.35
1.20
1.2
1.5
0.00
0.04
estimate
1.49
47
348
142
1673
0.85
1.20
1.2
1.2
—
—
—
0
0
13
71
1.83
1.19
1.0
1.1
1.57
1.58
umol/24h
0.00
13
71
546
5036
1.09
1.17
1.7
1.9
1.32
1.35
g/l
0.23
509
4719
952
8970
1.07
1.16
2.0
2.1
29.06
28.88
s
0.37
922
8700
0
33
0.00
1.16
0.0
1.1
—
32.24
—
0
33
5
20
2.50
1.15
2.8
1.9
—
—
—
0
0
5
20
2.50
1.15
1.0
1.0
0.91
3.48
u/ml
—
5
14
83
669
1.24
1.14
1.7
1.9
15.50
25.24
mg/l
2.23
30
255
184
1597
1.16
1.14
2.5
2.6
21.62
28.51
iu/ml
0.41
12
83
453
4149
1.10
1.14
9.5
7.2
7.68
7.10
mmol/l
1.21
434
4007
28
191
1.47
1.13
3.3
2.3
16.15
16.07
%
0.05
28
191
368
4050
0.90
1.12
1.2
1.2
—
—
—
0
0
523
4827
1.09
1.11
4.4
3.6
7.38
7.38
ph
0.06
282
2581
315
2838
1.11
1.10
1.1
1.1
—
—
—
0
0
1104
10480
1.06
1.08
3.4
3.1
0.82
0.83
mmol/l
0.97
1051
9952
1861
17917
1.05
1.08
2.2
2.1
294.71
295.50
umol/l
0.15
1701
16427
33
456
0.72
1.08
1.2
1.5
122.33
129.57
nmol/l
0.51
33
456
127
1490
0.85
1.05
2.0
2.1
—
—
—
0
0
797
7496
1.07
1.05
6.5
5.1
1.04
1.04
mmol/l
0.01
745
6973
105
1250
0.84
1.03
1.2
1.1
95.66
93.90
%
0.26
100
1179
764
8124
0.93
1.03
1.6
1.7
—
—
—
0
0
230
2044
1.13
1.03
1.3
1.4
332.45
312.83
ug/g
0.62
123
1036
118
998
1.18
1.03
5.4
6.0
373.04
374.47
umol/l
0.03
109
860
17
106
1.60
1.02
1.2
1.2
—
—
—
0
0
551
5121
1.08
1.01
1.1
1.1
—
—
—
0
0
158
1816
0.87
1.01
1.3
1.3
5.80
4.16
u/ml
0.24
79
785
229
2038
1.13
1.01
1.3
1.2
280.76
259.57
u/ml
0.64
167
1347
226
2011
1.13
1.00
1.0
1.1
0.15
0.21
u/ml
0.26
49
590
530
4921
1.08
1.00
3.6
3.1
1.23
1.23
mmol/l
0.90
453
4277
81
984
0.82
1.00
2.7
2.5
51.96
84.72
ug/min
0.68
52
629
1165
11107
1.06
1.00
2.6
2.3
2.43
2.49
g/l
2.87
1055
10303
45
343
1.31
0.99
1.2
1.3
6.05
6.01
mmol/l
0.03
40
318
218
1938
1.13
0.99
1.2
1.2
—
—
—
0
0
98
820
1.20
0.98
1.2
1.2
—
—
—
0
0
40
301
1.33
0.96
1.5
1.7
167.29
148.32
au/ml
—
8
40
17
108
1.58
0.96
2.8
2.1
545461.59
331039.66
nmol/l
0.15
11
87
732
6893
1.07
0.95
1.5
1.6
289.00
309.66
mu/l
0.80
660
6137
195
2195
0.89
0.93
1.2
1.1
8.21
14.40
au/ml
2.72
62
686
17
109
1.56
0.93
1.2
1.3
—
—
—
0
0
3966
38891
1.04
0.92
2.5
2.5
75.35
2299.12
nmol/l
0.50
3742
36866
14
86
1.63
0.90
1.6
2.0
6.71
7.41
ug/l
0.11
14
86
50
630
0.79
0.89
20.0
19.3
1448.02
4119.21
nmol/l
0.80
50
608
16
242
0.66
0.88
2.3
3.1
29.18
27.49
umol/l
0.38
11
184
425
3938
1.08
0.87
3.8
3.1
4.61
4.61
kpa
0.00
416
3813
430
4633
0.92
0.87
1.1
1.1
0.52
0.58
ratio
1.37
37
459
274
2491
1.10
0.86
3.8
3.1
0.58
0.62
%
1.84
274
2478
24
334
0.72
0.86
1.3
1.2
26.08
27.99
s
2.63
24
334
1046
10946
0.95
0.86
1.5
1.5
3.44
3.44
mmol/l
0.00
679
7111
153
1346
1.14
0.85
2.5
2.0
131.10
130.41
g/l
0.14
115
1088
127
1103
1.15
0.85
3.6
2.8
2.04
2.24
mmol/l
0.29
72
671
80
669
1.20
0.84
1.1
1.2
—
—
—
0
0
290
2650
1.10
0.83
1.2
1.1
—
—
—
0
0
818
7773
1.06
0.82
3.6
3.6
4.66
4.56
pmol/l
1.49
743
7106
142
1247
1.14
0.82
1.4
1.3
—
—
—
0
0
6
32
1.88
0.81
1.2
1.1
—
—
—
0
0
6
32
1.88
0.81
1.0
1.4
—
—
—
0
0
23
163
1.41
0.81
1.7
1.7
—
—
—
0
0
48
600
0.80
0.81
16.5
14.5
854.13
2979.22
nmol/l
0.49
48
580
499
4669
1.07
0.81
3.7
3.4
76.04
74.58
ng/l
0.14
452
4205
201
1805
1.12
0.81
2.8
2.5
1.40
2.07
index
1.11
108
912
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
32
419
0.76
0.79
2.7
2.9
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
35
268
1.31
0.79
1.3
1.4
—
—
—
0
0
22
156
1.41
0.78
1.1
1.8
—
—
—
0
0
0
26
0.00
0.78
0.0
1.2
—
31.08
—
0
26
115
999
1.15
0.78
5.4
6.7
11.13
11.18
mmol/l
0.07
104
898
12
74
1.62
0.78
1.1
2.0
0.75
0.89
u/field
0.20
12
74
115
1000
1.15
0.77
5.4
6.7
106.14
105.65
mmol/l
0.64
104
899
61
502
1.22
0.77
3.9
2.8
—
—
—
0
0
288
2644
1.09
0.77
1.1
1.1
—
—
—
0
0
273
2503
1.09
0.75
3.9
3.2
1.59
1.35
%
2.19
273
2486
352
3263
1.08
0.75
2.1
2.2
4.57
5.11
umol/l
0.76
248
2384
148
1313
1.13
0.75
5.0
3.4
62.95
62.01
%
0.21
142
1265
32
244
1.31
0.75
1.2
1.3
—
—
—
0
0
426
3981
1.07
0.74
2.6
2.5
73.21
71.84
e9/l
0.24
311
2797
369
3431
1.08
0.73
2.3
2.2
35.30
5.38
iu/l
0.48
175
1594
8
132
0.61
0.73
1.3
1.1
—
—
—
0
0
76
644
1.18
0.72
1.6
1.7
281.52
281.82
mosm/kgh2o
0.04
56
518
6
110
0.55
0.71
1.0
1.4
—
—
—
0
0
32
246
1.30
0.71
1.9
1.5
—
—
—
0
0
330
3060
1.08
0.71
2.4
2.5
122.88
107.18
ng/l
0.32
293
2740
130
1468
0.88
0.71
2.1
2.0
4.85
5.45
mmol/24h
1.78
125
1353
290
2676
1.09
0.70
1.1
1.1
2.13
1.55
u/ml
0.39
129
1313
226
2062
1.10
0.70
1.3
1.3
—
—
—
0
0
614
6473
0.94
0.70
1.5
1.5
1.27
1.26
mm
0.29
427
4701
9
58
1.55
0.69
1.0
1.2
—
—
—
0
0
9
58
1.55
0.69
1.1
1.1
—
—
—
0
0
9
142
0.63
0.69
1.3
1.2
—
—
—
0
0
261
2401
1.09
0.69
1.1
1.1
4.86
4.09
u/ml
0.24
126
1159
9
59
1.53
0.68
1.0
1.7
—
—
—
0
0
92
797
1.16
0.68
1.1
1.2
118.16
118.40
pmol/l
0.01
92
797
1269
12258
1.04
0.67
2.6
2.3
15.08
14.58
umol/l
1.47
1177
11525
638
6711
0.95
0.67
1.5
1.6
—
—
—
0
0
600
5692
1.06
0.67
2.4
2.6
1.75
1.73
%
0.19
540
5141
35
441
0.79
0.67
1.1
1.1
—
—
—
0
0
83
715
1.16
0.66
1.1
1.1
—
—
—
0
0
41
506
0.81
0.66
1.1
1.2
58.93
68.88
ug/l
1.01
41
506
1275
12331
1.04
0.64
2.7
2.6
861.78
558.82
ng/l
0.92
1049
9986
264
2440
1.08
0.64
1.2
1.3
—
—
—
0
0
26
198
1.31
0.63
2.4
2.4
—
—
—
0
0
34
269
1.26
0.63
1.3
1.4
34608.00
71546.98
e6/l
0.52
20
136
39
314
1.24
0.63
1.2
1.4
12824.19
2755.92
e6/l
0.48
27
212
27
348
0.78
0.63
1.4
2.1
0.30
0.18
e9/l
0.34
12
155
68
580
1.17
0.62
2.5
2.6
1.27
1.22
g/24h
0.06
44
339
320
3429
0.93
0.62
1.2
1.2
—
—
—
0
0
96
842
1.14
0.61
1.1
1.1
—
—
—
0
0
2036
19873
1.03
0.61
1.8
1.8
0.99
0.88
mg/l
0.74
1528
15117
138
1535
0.90
0.61
1.5
1.5
0.63
0.61
g/l
0.10
104
1199
3777
38348
0.97
0.61
2.5
2.5
—
—
—
0
0
7363
73176
1.03
0.61
3.4
3.5
1.17
1.18
mmol/l
0.10
7031
70137
246
2274
1.08
0.60
1.1
1.1
3.91
4.52
u/ml
0.30
101
1013
210
1928
1.09
0.60
1.4
1.3
147.03
152.82
au/ml
0.30
57
508
0
20
0.00
0.60
0.0
1.1
—
97.08
—
0
13
8
52
1.54
0.59
1.0
1.0
0.03
0.04
u/ml
—
8
52
8
52
1.54
0.59
1.4
1.6
322.25
306.19
umol/24h
—
8
52
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
626
6556
0.95
0.58
1.5
1.5
—
—
—
0
0
536
5097
1.05
0.58
2.2
2.3
0.26
0.30
e6/l
0.28
498
4755
225
2077
1.09
0.58
3.4
2.9
232.44
347.26
mg/l
1.45
89
870
52
616
0.84
0.57
6.6
7.2
6.46
53.96
ug/l
1.05
33
409
485
4601
1.06
0.57
8.8
7.0
1.22
1.23
mmol/l
0.10
475
4515
12
173
0.69
0.57
1.0
1.0
0.58
0.14
u/ml
—
7
97
12
81
1.48
0.57
1.4
1.1
90.67
85.73
titre
0.07
12
81
304
2843
1.07
0.56
5.5
6.3
24.26
24.22
mmol/l
0.07
293
2707
51
429
1.19
0.56
1.9
2.0
8.78
9.43
mg/l
0.40
39
363
151
1373
1.10
0.55
1.7
1.7
7007.01
8441.77
e6/l
0.46
106
996
32
257
1.25
0.55
1.3
1.4
—
—
—
0
0
142
1290
1.10
0.53
1.4
1.2
44.88
1351.77
pmol/l
0.91
13
102
9
62
1.45
0.53
1.1
1.0
—
—
—
0
0
816
7864
1.04
0.52
1.4
1.5
1.20
1.16
ratio
0.60
472
4733
42
350
1.20
0.52
2.6
3.6
0.77
0.80
nmol/l
0.19
28
278
133
1207
1.10
0.51
4.1
2.8
—
—
—
0
0
19
248
0.77
0.51
1.0
1.0
24.53
8.33
u/ml
0.37
19
248
221
2053
1.08
0.51
1.3
1.3
19.34
21.04
u/ml
—
5
41
61
527
1.16
0.51
2.0
1.6
1.84
13.08
nmol/l
0.57
52
427
180
1659
1.09
0.50
4.5
5.0
1.15
1.22
mmol/l
0.77
163
1467
334
3150
1.06
0.50
3.2
2.8
5.19
5.08
kpa
1.59
319
3037
102
914
1.12
0.50
1.2
1.3
—
—
—
0
0
79
892
0.88
0.49
1.1
1.2
0.61
1.51
u/ml
1.51
33
494
47
399
1.18
0.49
2.5
2.3
—
—
—
0
0
269
2524
1.07
0.48
1.2
1.2
—
—
—
0
0
1015
9843
1.04
0.48
2.7
2.4
24.20
23.73
%
0.51
927
9184
13
177
0.73
0.47
1.0
1.1
—
—
—
0
0
1096
10648
1.03
0.47
1.2
1.2
—
—
—
0
0
12
85
1.41
0.46
1.1
1.6
10.40
26.70
g/l
—
7
63
7
48
1.46
0.46
1.0
1.1
—
—
—
0
0
314
2967
1.06
0.46
3.7
3.1
129.60
130.33
g/l
0.24
306
2886
13
94
1.38
0.45
1.8
2.0
—
—
—
0
0
42
356
1.18
0.45
2.3
2.4
—
—
—
0
0
7
50
1.40
0.45
1.7
3.2
—
—
—
0
0
7
50
1.40
0.45
1.1
1.2
—
—
—
0
0
918
8903
1.03
0.44
2.1
2.1
386.37
379.53
nmol/l
0.50
865
8297
74
657
1.13
0.44
3.7
3.8
5.98
7.18
mmol/l
3.18
64
546
101
1115
0.90
0.44
4.3
4.7
85.68
104.43
u/ml
0.13
49
398
1214
12456
0.97
0.44
1.3
1.3
—
—
—
0
0
7
51
1.37
0.44
1.9
3.8
9.43
8.01
mmol/l
—
7
51
30
362
0.83
0.44
1.1
1.2
—
—
—
0
0
143
1551
0.92
0.43
2.3
1.9
4.64
1.59
ug/l
1.02
122
1378
59
517
1.14
0.43
2.1
2.4
—
—
—
0
0
74
660
1.12
0.42
1.5
1.5
23.85
24.36
umol/l
0.05
67
614
45
520
0.86
0.41
1.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
0.10
—
0
15
89
804
1.11
0.41
1.0
1.0
—
—
—
0
0
89
983
0.90
0.40
1.2
1.3
0.16
0.19
nmol/l
0.72
67
681
121
1111
1.09
0.40
1.1
1.1
1.48
1.47
g/l
0.14
113
1029
803
7788
1.03
0.40
1.4
1.5
—
—
—
0
0
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
7864
78359
1.03
0.39
4.4
4.4
2.86
2.87
mmol/l
1.05
7547
75338
55
622
0.88
0.38
2.8
2.4
568.04
517.39
e6/l
0.54
46
483
307
3225
0.95
0.38
1.1
1.1
3.70
4.83
eliau/ml
0.47
61
520
42
484
0.87
0.38
1.3
1.2
63.43
71.04
%
—
7
49
168
1569
1.07
0.38
1.1
1.1
—
—
—
0
0
91
999
0.91
0.38
1.4
1.5
—
—
—
0
0
320
3050
1.05
0.37
3.2
2.7
7.41
7.42
ph
0.61
267
2540
92
1009
0.91
0.37
1.4
1.4
0.41
0.37
g/l
0.44
66
737
853
8294
1.03
0.37
1.5
1.5
61.94
61.93
ug/l
0.00
693
6859
29
243
1.19
0.37
1.1
1.1
—
—
—
0
0
29
243
1.19
0.37
1.1
1.1
—
—
—
0
0
29
243
1.19
0.37
1.1
1.1
—
—
—
0
0
13
98
1.33
0.37
1.0
1.1
0.08
0.51
u/ml
—
5
40
69
619
1.12
0.37
1.2
1.2
217.50
213.89
titre
0.01
12
108
8
112
0.71
0.37
1.0
1.0
0.89
0.47
u/ml
—
8
104
92
1008
0.91
0.37
1.4
1.4
2.94
3.02
g/l
0.21
65
733
92
1008
0.91
0.37
1.4
1.4
6.78
6.55
g/l
0.20
65
736
1633
16637
0.98
0.36
3.4
3.5
56.47
51.34
mg/l
0.32
1005
10063
55
488
1.13
0.35
1.4
1.6
30847.06
47104.62
e6/l
0.22
35
330
7817
77911
1.03
0.34
4.0
4.1
4.81
4.82
mmol/l
0.86
7527
75181
37
320
1.16
0.34
1.0
1.1
29.46
26.70
iu/ml
0.12
37
320
1046
10219
1.03
0.34
1.3
1.3
174.24
148.12
u/ml
0.95
412
4127
488
5055
0.96
0.34
1.1
1.1
—
—
—
0
0
44
500
0.88
0.34
1.0
1.0
19.45
8.70
u/ml
1.80
26
349
96
1044
0.92
0.34
2.2
2.5
1.37
1.35
mmol/l
0.07
96
1015
6
45
1.33
0.33
1.5
2.2
310.17
245.90
ug/l
—
6
45
123
1323
0.93
0.33
2.1
2.3
—
—
—
0
0
97
892
1.09
0.33
1.2
1.2
—
—
—
0
0
59
657
0.90
0.33
3.1
2.5
240.65
235.67
e6/l
0.08
52
535
112
1037
1.08
0.33
1.5
1.5
728.61
502.50
pmol/l
0.38
98
922
6
46
1.30
0.33
1.0
1.3
269.33
164.74
ug/g
—
6
35
60
539
1.11
0.33
3.6
2.7
895.05
733.72
u/ml
0.16
60
534
26
219
1.19
0.33
1.2
1.1
—
—
—
0
0
598
5799
1.03
0.33
1.1
1.1
72.77
204.77
titre
3.18
13
156
118
1096
1.08
0.32
3.2
3.4
—
—
—
0
0
89
817
1.09
0.32
1.3
1.3
990.91
1076.57
titre
0.17
11
175
6
47
1.28
0.32
1.7
1.4
—
—
—
0
0
180
1906
0.94
0.32
1.0
1.1
2.84
2.98
eliau/ml
0.07
104
1046
284
2715
1.05
0.32
1.3
1.3
43.06
39.82
u/ml
0.13
32
257
12
92
1.30
0.31
1.2
1.2
—
—
—
0
0
77
842
0.91
0.31
1.5
1.4
—
—
—
0
0
77
842
0.91
0.31
1.5
1.4
—
—
—
0
0
30
348
0.86
0.31
2.4
2.2
1.66
1.16
ug/l
0.54
30
334
50
559
0.89
0.31
1.0
1.1
0.08
2.25
nmol/l
—
6
91
7
52
1.35
0.31
1.7
3.1
—
—
—
0
0
20
165
1.21
0.31
2.0
2.0
42.59
41.47
g/l
0.47
20
165
23
193
1.19
0.30
1.0
1.0
—
—
—
0
0
107
1151
0.93
0.30
1.2
1.3
0.51
3.05
nmol/l
0.79
101
1118
77
840
0.92
0.30
1.5
1.4
—
—
—
0
0
77
840
0.92
0.30
1.5
1.4
—
—
—
0
0
107
994
1.08
0.30
1.4
1.5
—
—
—
0
0
203
1928
1.05
0.30
4.8
5.0
0.88
0.91
%
0.54
193
1819
104
966
1.08
0.30
1.0
1.1
0.31
1.38
u/ml
1.73
27
289
138
1469
0.94
0.30
1.1
1.2
116.74
8057.14
iu/ml
0.63
32
334
29
335
0.87
0.29
1.2
1.1
—
—
—
0
0
10
130
0.77
0.29
1.2
1.1
2.41
1.99
iu/ml
—
5
69
289
2772
1.04
0.29
1.0
1.1
5.53
4.81
u/ml
0.34
145
1477
7184
72101
0.98
0.28
15.7
14.8
332.20
331.88
g/l
2.64
7150
71711
15
121
1.24
0.28
1.0
1.0
0.08
0.27
u/ml
—
8
73
66
603
1.10
0.28
1.7
1.4
—
—
—
0
0
45
502
0.90
0.28
1.0
1.1
13.12
10.17
u/ml
—
6
88
57
517
1.10
0.28
1.7
1.6
37.48
41.48
%
0.30
33
302
274
2630
1.04
0.27
1.0
1.1
1.35
0.90
u/ml
0.43
109
1119
219
2292
0.95
0.27
8.0
7.3
—
—
—
0
0
96
894
1.07
0.27
1.0
1.0
0.70
0.36
u/ml
0.30
17
182
339
3271
1.04
0.27
1.5
1.8
—
—
—
0
0
65
596
1.09
0.26
1.1
1.2
6.86
14.10
u/ml
—
7
77
12
95
1.26
0.26
2.7
2.1
—
—
—
0
0
18
151
1.19
0.25
1.9
1.7
—
—
—
0
0
148
1404
1.06
0.25
1.4
1.3
34.14
59.93
u/ml
—
8
82
12
96
1.25
0.24
1.0
1.1
—
—
—
0
0
150
1425
1.05
0.24
1.4
1.5
—
—
—
0
0
69
638
1.08
0.24
1.2
1.2
9.52
9.41
mm/h
0.03
69
638
6
83
0.72
0.24
1.0
1.1
11.78
12.32
pmol/l
—
6
83
37
331
1.12
0.24
1.2
1.1
—
—
—
0
0
23
264
0.87
0.23
1.7
2.0
—
—
—
0
0
7783
77643
1.02
0.23
4.0
4.0
1.55
1.54
mmol/l
0.37
7479
74714
16
134
1.19
0.22
1.1
1.1
—
—
—
0
0
165
1727
0.95
0.22
1.4
1.5
33.00
35.11
nmol/l
0.44
156
1602
1393
14125
0.98
0.22
1.7
1.7
3.27
3.25
ratio
0.20
1008
10136
102
961
1.06
0.22
1.2
1.2
—
—
—
0
0
73
680
1.07
0.22
1.8
1.7
47.93
48.97
%
0.08
45
418
15
178
0.84
0.22
1.1
1.1
—
208.00
—
0
10
784
7692
1.02
0.22
1.2
1.3
264.84
185.90
u/ml
0.78
736
7179
0
11
0.00
0.21
0.0
1.0
—
0.02
—
0
6
0
10
0.00
0.21
0.0
1.1
—
0.22
—
0
5
0
10
0.00
0.21
0.0
1.7
—
12.28
—
0
5
169
1764
0.96
0.21
1.4
1.4
1.48
1.41
nmol/l
0.17
148
1517
23
201
1.14
0.21
1.5
1.1
—
—
—
0
0
46
502
0.92
0.21
1.5
1.4
—
—
—
0
0
14
117
1.20
0.20
1.8
2.7
—
—
—
0
0
172
1650
1.04
0.20
2.2
2.1
385.52
290.30
ug/l
0.36
159
1482
405
4156
0.97
0.20
1.7
1.7
19.14
9.93
u/ml
1.00
113
1171
26
292
0.89
0.20
1.0
1.1
5.05
5.29
mg/g
0.15
26
278
69
645
1.07
0.19
1.4
1.6
5.77
5.83
mmol/l
0.06
54
534
1667
16856
0.99
0.19
4.0
4.1
10.77
9.22
mg/mmol
0.40
1014
10208
328
3189
1.03
0.19
1.1
1.1
2.52
1.94
u/ml
0.44
169
1652
255
2469
1.03
0.19
1.3
1.3
109.60
142.15
titre
0.25
25
251
130
1361
0.95
0.19
3.6
3.3
27.39
21.37
mg/l
0.73
75
884
25
222
1.13
0.19
2.0
1.7
8.61
8.80
ug/l
0.09
25
222
330
3391
0.97
0.19
1.8
1.9
20.08
20.15
s
0.12
279
2890
175
1816
0.96
0.18
1.5
1.5
6.98
6.63
mmol/l
0.87
167
1653
78
826
0.94
0.17
2.4
2.6
6.76
7.19
mmol/l
0.87
78
801
156
1501
1.04
0.17
1.1
1.1
—
—
—
0
0
170
1639
1.04
0.17
1.1
1.1
—
—
—
0
0
27
299
0.90
0.17
2.6
2.4
596.90
612.57
ml
0.10
20
240
394
4026
0.98
0.16
1.3
1.3
3.57
3.10
ug/l
0.25
363
3730
39
360
1.08
0.16
1.4
1.6
1.56
2.41
u/field
0.69
27
262
6
80
0.75
0.15
12.3
12.6
6.52
5.97
kpa
—
6
80
125
1202
1.04
0.15
2.8
3.8
3.80
3.77
mmol/l
0.33
125
1192
691
6807
1.02
0.15
1.2
1.2
—
—
—
0
0
1439
14530
0.99
0.15
1.5
1.6
1026.90
1025.99
mu/l
0.01
1157
12125
9
82
1.10
0.15
2.4
2.5
—
—
—
0
0
17
192
0.89
0.14
1.1
1.1
—
—
—
0
0
49
459
1.07
0.14
2.8
2.8
157.83
57.28
mg/l
0.39
34
322
47
502
0.94
0.14
1.5
1.4
67.13
67.67
umol/l
0.09
47
502
93
971
0.96
0.14
1.2
1.4
—
—
—
0
0
86
822
1.05
0.14
2.6
2.4
1591.73
1371.30
e6/l
0.49
77
697
82
783
1.05
0.13
1.2
1.1
1.07
1.05
ratio
0.35
65
664
8
98
0.82
0.13
1.6
1.5
—
—
—
0
0
13
149
0.87
0.13
1.2
1.6
—
—
—
0
0
217
2114
1.03
0.13
4.6
4.7
1.88
1.68
%
1.18
206
2000
65
617
1.05
0.13
2.4
2.6
—
—
—
0
0
208
2136
0.97
0.13
1.2
1.2
3.52
3.58
mmol/l
0.37
203
2022
122
1263
0.97
0.13
2.9
3.2
0.95
0.88
nmol/l
0.47
109
1084
14
123
1.14
0.12
1.1
1.2
7.51
7.42
ph
—
9
81
11
127
0.87
0.12
1.1
1.0
0.02
0.04
u/ml
0.91
11
127
10
85
1.18
0.12
1.0
1.0
0.10
0.71
u/ml
—
5
42
35
375
0.93
0.12
1.5
2.2
1.19
1.43
nmol/l
0.76
30
297
77
804
0.96
0.12
1.3
1.2
0.66
0.66
ratio
0.01
38
488
50
473
1.06
0.12
3.1
2.7
116.32
136.88
nmol/l
0.13
50
466
117
1132
1.03
0.11
2.1
2.0
—
—
—
0
0
156
1603
0.97
0.11
3.2
2.6
24.70
24.65
mmol/l
0.07
147
1496
106
1025
1.03
0.11
1.1
1.2
33.39
35.81
mg/l
0.38
81
875
203
1984
1.02
0.11
2.6
3.0
25.49
25.32
mmol/l
0.34
196
1907
94
907
1.04
0.11
3.3
3.8
167.34
518.21
u/ml
0.60
87
829
67
699
0.96
0.10
1.7
1.7
2.88
2.39
u/ml
0.16
20
181
103
997
1.03
0.10
1.2
1.1
27.05
16.40
u/ml
0.73
43
479
203
2073
0.98
0.10
1.2
1.3
77.93
32.42
e6/l
0.33
152
1550
30
320
0.94
0.09
1.2
1.2
6.42
5.65
nmol/l
0.66
30
303
116
1128
1.03
0.09
2.1
1.8
37.14
54.72
mu/l
1.65
110
1034
41
389
1.05
0.09
1.2
1.1
—
—
—
0
0
25
268
0.93
0.09
1.1
1.1
1.42
1.36
u/ml
0.01
14
172
18
196
0.92
0.09
1.7
1.4
5.28
5.48
mmol/l
0.58
18
196
414
4090
1.01
0.08
1.2
1.3
10.63
11.65
u/l
0.85
339
3403
42
440
0.95
0.08
1.3
1.3
136.19
145.68
mmol/24h
0.47
42
440
17
156
1.09
0.08
2.7
2.3
399.20
827.17
e6/l
—
10
105
28
297
0.94
0.08
1.6
1.5
2.40
4.37
%
—
5
56
25
266
0.94
0.07
1.4
1.5
—
—
—
0
0
39
373
1.05
0.07
1.1
1.2
—
—
—
0
0
208
2112
0.98
0.07
1.2
1.3
615.64
3156.95
e6/l
0.77
162
1673
18
167
1.08
0.06
1.1
1.1
—
—
—
0
0
8
94
0.85
0.06
2.5
2.0
1.19
1.19
mmol/l
—
8
87
51
492
1.04
0.06
1.1
1.1
—
—
—
0
0
102
997
1.02
0.06
1.0
1.1
194.74
210.59
mg/l
0.83
86
887
25
236
1.06
0.06
3.0
2.2
8.13
8.12
mmol/l
0.01
25
236
83
809
1.03
0.06
1.1
1.1
—
—
—
0
0
348
3516
0.99
0.06
1.5
1.5
0.51
0.49
nmol/l
0.18
280
2841
17
158
1.08
0.06
1.1
1.0
0.34
0.67
u/ml
—
7
70
36
345
1.04
0.06
1.0
1.1
—
—
—
0
0
73
711
1.03
0.06
1.9
1.7
—
—
—
0
0
168
1655
1.02
0.05
3.4
3.9
33.80
25.84
u/ml
0.44
156
1599
20
188
1.06
0.05
1.2
1.2
—
—
—
0
0
241
2438
0.99
0.05
1.3
1.3
1291.82
960.21
titre
0.32
11
97
241
2383
1.01
0.05
1.2
1.3
512.56
452.36
mg/l
0.39
232
2296
45
465
0.97
0.05
1.6
1.8
3.86
1.83
u/field
0.69
28
261
76
743
1.02
0.05
1.2
1.2
16.14
25.17
u/l
1.10
69
649
52
535
0.97
0.05
1.5
1.4
4.35
5.14
u/l
1.96
42
473
96
942
1.02
0.04
1.0
1.0
0.91
1.75
u/ml
0.35
18
214
1446
14416
1.00
0.04
1.6
1.6
30540323.95
32752411.80
pmol/l
0.06
1241
12729
21
200
1.05
0.03
1.1
1.4
7.19
8.14
mmol/l
0.63
21
200
76
746
1.02
0.03
1.1
1.1
—
—
—
0
0
3188
31928
1.00
0.03
1.8
1.8
1.33
1.31
mmol/l
0.88
2785
28266
195
1968
0.99
0.03
1.2
1.3
—
—
—
0
0
28
290
0.97
0.03
1.2
1.2
27.80
15.91
%
—
5
45
43
441
0.97
0.03
1.8
1.4
84.77
220.09
nmol/24h
0.97
43
441
56
549
1.02
0.03
2.0
2.1
1.08
0.85
%
0.79
36
311
42
430
0.98
0.02
1.3
1.2
—
—
—
0
0
13
138
0.94
0.02
1.1
1.3
0.80
161.72
mg/l
—
7
103
19
182
1.04
0.02
1.2
1.2
—
—
—
0
0
179
1800
0.99
0.01
1.3
1.2
—
—
—
0
0
22
213
1.03
0.01
1.2
1.1
—
—
—
0
0
22
213
1.03
0.01
1.2
1.1
—
—
—
0
0
22
213
1.03
0.01
1.2
1.1
—
—
—
0
0
92
928
0.99
0.01
1.1
1.2
—
—
—
0
0
98
972
1.01
0.01
1.0
1.1
9.70
7.30
iu/ml
0.42
30
315
200
1992
1.00
0.01
1.1
1.1
—
—
—
0
0
33
324
1.02
0.00
1.2
1.3
—
1306.00
—
0
10
21
213
0.99
0.00
2.0
1.4
—
—
—
0
0
33
327
1.01
0.00
1.1
1.1
7.80
452.49
ng/l
—
10
78
14
136
1.03
0.00
3.3
2.1
—
—
—
0
0
41
414
0.99
0.00
1.3
1.1
—
—
—
0
0
13
128
1.02
0.00
2.3
2.6
—
—
—
0
0
13
132
0.98
0.00
2.8
2.1
1228.67
22285.95
e6/l
—
6
65
13
132
0.98
0.00
1.2
1.3
—
—
—
0
0
55
552
1.00
0.00
4.3
3.1
11.54
10.65
mmol/l
0.81
55
539
66
662
1.00
0.00
1.6
1.7
—
—
—
0
0
77
768
1.00
0.00
2.9
3.3
—
—
—
0
0
50
501
1.00
0.00
1.5
1.3
—
—
—
0
0
14
139
1.01
0.00
1.4
1.2
53.21
60.87
ug/l
1.75
14
139
18
180
1.00
-0.00
1.7
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
319.00
—
0
5
5
54
0.93
-0.00
1.6
1.9
14.58
14.87
ml/dl
—
5
49
5
57
0.88
-0.00
7.0
7.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.2
0.17
0.16
umol/l
—
6
69
0
5
0.00
-0.00
0.0
1.6
—
160.20
—
0
5
9
95
0.95
-0.00
1.1
1.1
—
0.92
—
0
10
51
510
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.0
1.1
138.86
139.17
mmol/l
—
7
64
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_CERVICAL_HSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_CERVICAL_HSIL 1.314 [1.17, 1.48] < 0.001
Birth year 0.991 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 1401 out of 43721 females with N14_CERVICAL_HSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_CERVICAL_HSIL.

N-year risk Females Males
1 0.103% No data
5 0.634% No data
10 1.524% No data
15 3.107% No data
20 5.718% No data

Relationships between endpoints

Index endpoint: N14_CERVICAL_HSIL – HSIL lesion of the cervix uteri

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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