Risteys ·

OMOP concept ID	Test name	Measurement unit (harmonized unit)	N people	N records	Missing measurement value	Harmonized value distribution	Test outcome NA N A AA L LL H HH
3036185	maksa-2-is	u/l (u/l)	862	974	0.00%
3036185	afosmaksa2	u/l (u/l)	497	557	0.18%
3036185	s-afmaks2	u/l (—)	164	184	100.00%	Distribution not available
3036185	afosmaksa2	— (—)	138	145	100.00%	Distribution not available
3036185	s-maksa-2	u/l (u/l)	99	110	0.00%
3036185	s-maksa2	u/l (u/l)	67	68	0.00%
3036185	s-afos2ma	u/l (—)	66	75	100.00%	Distribution not available
3036185	afosmaks2	u/l (—)	56	68	100.00%	Distribution not available
3036185	maksa-2-is	— (—)	55	62	100.00%	Distribution not available
3036185	s-maksa-2-isoentsyymi	u/l (u/l)	22	22	0.00%	Distribution not available
3036185	maksa-2-ls	u/l (u/l)	18	22	0.00%
3036185	maksa-2-isoentsyymi	u/l (u/l)	14	14	0.00%
3036185	s-maksa-2	— (—)	12	12	100.00%	Distribution not available
3036185	s-maksa2	— (—)	5	5	100.00%	Distribution not available	Distribution not available

LabWAS

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

Chronic kidney disease

285

437

6.61

175.61

1.2

1.1

32.68

28.42

u/l

0.36

235

305

Care involving dialysis

144

16.74

170.47

1.3

1.1

24.24

20.38

u/l

0.40

126

Dialysis, with operation codes

169

173

10.07

147.46

1.2

1.1

32.61

30.92

u/l

0.09

144

128

Renal failure

344

666

4.78

146.03

1.2

1.1

35.52

29.31

u/l

0.60

282

469

Diseases of liver

305

620

5.00

140.24

1.2

1.1

35.62

23.72

u/l

2.07

243

478

Anaemias

184

128

9.67

126.55

1.2

36.57

10.56

u/l

2.84

146

103

Nephropathy related operations

158

183

8.89

125.57

1.2

1.1

33.82

31.49

u/l

0.13

134

136

ILD medications: immunosuppressive drugs

405

1081

3.62

121.18

1.2

1.1

26.52

22.26

u/l

0.50

335

797

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

580

1382

3.03

120.46

1.2

1.1

34.75

21.29

u/l

3.11

454

1050

Extracorporeal dialysis

107

14.75

118.30

1.3

1.1

25.23

32.62

u/l

0.45

First line medication for Crohn's disease

619

1134

2.99

115.70

1.1

28.42

22.09

u/l

1.15

511

827

Secondary hypertension

116

11.97

113.31

1.3

1.1

30.58

18.35

u/l

0.87

100

Any gastric operation

399

504

3.99

108.82

1.2

1.1

21.90

17.79

u/l

0.61

333

283

GASTRO-related operations

399

504

3.99

108.82

1.2

1.1

21.90

17.79

u/l

0.61

333

283

Other diseases of liver

186

305

6.23

108.26

1.2

1.1

31.69

24.51

u/l

0.84

143

232

Renal tubulo-interstitial diseases

514

1330

2.98

106.19

1.2

1.1

34.83

21.81

u/l

3.08

402

1002

Autoimmune diseases excluding thyroid diseases

560

1046

2.99

105.02

1.1

25.62

23.59

u/l

0.24

447

796

Autoimmune diseases excluding thyroid diseases, strict definition

538

1012

2.98

100.55

1.1

23.57

23.99

u/l

0.05

431

768

Glomerular diseases

172

281

6.24

100.46

1.2

1.1

30.30

27.89

u/l

0.15

139

212

Preparatory care for dialysis

16.74

99.05

1.4

1.1

23.39

31.33

u/l

0.46

Abnormal findings on examination of blood, without diagnosis

307

776

3.74

95.56

1.2

1.1

29.01

26.85

u/l

0.22

230

584

Glomerular disorders in diseases classified elsewhere

129

164

8.06

95.00

1.2

1.1

35.18

30.34

u/l

0.22

101

120

Autoimmune diseases related-to ILD

483

1508

2.83

94.52

1.1

24.26

25.08

u/l

0.08

393

1133

ILD medications

596

1220

2.69

93.11

1.1

29.61

22.05

u/l

1.45

488

896

Other bacterial diseases

529

1336

2.75

92.19

1.2

1.1

36.28

21.29

u/l

4.01

415

1014

ILD medications: prednisolone, methylprednisolone, prednisone

579

1216

2.70

91.89

1.1

31.09

22.07

u/l

1.82

473

895

Transplanted organ and tissue status

109

131

8.53

84.09

1.3

1.1

32.76

24.65

u/l

0.59

Autoimmune diseases

553

1061

2.67

83.25

1.1

26.29

23.41

u/l

0.34

428

808

Dialysis

15.00

81.42

1.4

1.1

24.51

18.88

u/l

0.48

Inflammatory bowel disease treatment related agents

586

1330

2.51

81.10

1.1

28.56

23.00

u/l

0.91

473

989

Insulin, fast-acting

239

618

3.90

80.69

1.2

1.1

39.22

24.24

u/l

1.53

173

468

Insulin, fast-acting or short human

239

635

3.80

77.65

1.2

1.1

39.22

26.39

u/l

1.20

173

487

Used for control exclusion in common control thyroid runs

502

960

2.66

74.89

1.1

27.10

23.58

u/l

0.40

394

734

Oral corticosteroids

537

1313

2.49

74.06

1.1

30.15

23.07

u/l

1.17

432

981

Other dialysis

15.24

73.85

1.3

1.1

25.45

25.21

u/l

0.01

Bacterial infection, other or unspecified

304

868

3.18

73.40

1.2

1.1

44.39

22.81

u/l

3.49

246

643

Heart failure, not strict

416

1046

2.76

72.85

1.2

1.1

32.08

24.68

u/l

1.12

317

797

Fever of other and unknown origin

303

920

3.07

69.55

1.2

1.1

39.57

20.49

u/l

2.87

256

703

Other septicaemia

225

607

3.67

69.33

1.2

1.1

37.59

22.96

u/l

2.51

179

446

Aplastic and other anaemias

272

799

3.26

68.99

1.2

1.1

38.05

26.58

u/l

1.21

218

581

Kidney transplant status

11.66

68.46

1.4

1.1

25.05

22.68

u/l

0.13

Type 1 diabetes, wide definition, subgroup 1

146

294

5.02

67.95

1.2

1.1

38.46

21.15

u/l

1.29

101

232

Diabetic nephropathy, excluding more controls

136

208

5.56

66.08

1.2

1.1

38.96

32.41

u/l

0.30

161

Fibrosis and cirrhosis of liver

116

7.90

64.32

1.1

1.0

35.53

22.10

u/l

1.57

Malignant neoplasm of breast

323

805

2.92

63.41

1.2

1.1

17.30

25.36

u/l

2.12

277

600

Insulin, intermediate and long-acting

297

1008

2.91

62.78

1.2

1.1

39.21

23.81

u/l

2.16

219

757

Persons with potential health hazards related to family and personal history and certain conditions influencing health status

473

1345

2.40

62.70

1.2

1.1

24.72

25.14

u/l

0.05

373

1012

Malignant neoplasm of breast, ER-positive, excluding all cancers (controls excluding all cancers)

235

560

3.44

62.31

1.2

1.1

17.97

21.20

u/l

0.48

209

411

Septicaemia

236

688

3.33

62.27

1.2

1.1

37.27

24.57

u/l

1.87

188

505

Malignant neoplasm of breast, HER2-negative, excluding all cancers (controls excluding all cancers)

295

628

3.10

62.06

1.2

1.1

17.02

20.39

u/l

0.62

253

465

Malignant neoplasm of breast, excluding all cancers (controls excluding all cancers)

295

628

3.10

62.06

1.2

1.1

17.02

20.39

u/l

0.62

253

465

Type 1 diabetes

161

380

4.27

61.59

1.2

1.1

36.01

23.24

u/l

0.93

114

295

Malignant neoplasm

450

1088

2.47

60.79

1.2

1.1

31.10

22.84

u/l

1.25

368

815

Type 1 diabetes, wide definition

147

327

4.54

60.71

1.2

1.1

39.19

20.85

u/l

1.43

102

256

Diabetic nephropathy

137

285

4.84

60.48

1.2

1.1

38.96

36.67

u/l

0.09

228

Disorders of gallbladder, biliary tract and pancreas

497

1385

2.32

60.45

1.2

1.1

29.46

23.97

u/l

0.78

375

1063

Malignant neoplasm of breast, HER2-negative

313

806

2.88

60.25

1.2

1.1

17.34

25.45

u/l

2.10

271

599

Insulin, combination of fast acting with intermediate-acting or long-acting

322

1091

2.74

59.97

1.2

1.1

38.97

24.22

u/l

2.27

242

821

Abnormal serum enzyme levels

187

495

3.77

59.97

1.2

1.1

28.72

31.32

u/l

0.18

135

377

L04AD Calcineurin inhibitors

101

163

6.32

59.88

1.3

1.1

33.35

23.17

u/l

0.79

125

Insulin medication

322

1004

2.76

59.82

1.2

1.1

38.97

22.67

u/l

2.70

242

756

Explicit Sepsis

242

743

3.15

58.35

1.2

1.1

36.86

23.18

u/l

2.49

193

552

Acute renal failure

138

303

4.61

58.10

1.2

1.1

50.65

29.49

u/l

1.33

113

218

L02BG Aromatase inhibitors

211

630

3.39

57.80

1.2

1.1

18.43

23.47

u/l

0.78

189

466

Any reimbursement code in KELA

233

319

3.67

57.54

1.2

1.1

19.60

18.68

u/l

0.09

183

243

Second line medication for Crohn's disease

312

1164

2.70

57.50

1.2

1.1

23.79

24.81

u/l

0.08

261

892

Malignant neoplasm of breast, HER-positive

235

740

3.17

57.43

1.2

1.1

17.97

24.66

u/l

1.26

209

556

Malignant neoplasm, excluding all cancers (controls excluding all cancers)

431

1056

2.42

56.21

1.2

1.1

30.87

21.60

u/l

1.44

349

796

Malignant neoplasm, wide definition for exclusion

431

1056

2.42

56.21

1.2

1.1

30.87

21.60

u/l

1.44

349

796

Malignant neoplasm, wide definition for exclusion, excluding all cancers (controls excluding all cancers)

431

1056

2.42

56.20

1.2

1.1

30.87

21.60

u/l

1.44

349

796

Nonalcoholic fatty liver disease

140

6.57

55.35

1.2

1.1

24.19

21.99

u/l

0.20

110

Implicit Sepsis

364

1138

2.50

54.42

1.1

36.48

22.42

u/l

2.35

275

852

Other and unspecified anaemias

232

735

3.08

54.03

1.1

41.24

27.40

u/l

1.30

186

537

Persons encountering health services in other circumstances

209

649

3.24

53.56

1.1

33.88

22.42

u/l

0.81

165

523

Other anaemias

234

747

3.05

53.51

1.1

41.07

27.25

u/l

1.31

187

545

Persons encountering health services for other counselling and medical advice, not elsewhere classified

512

1330

2.20

53.46

1.2

1.1

29.20

22.84

u/l

0.82

340

1069

Medicines for HER+ breast cancer

236

767

3.03

53.39

1.2

1.1

17.97

24.50

u/l

1.23

209

577

Anaemia in chronic diseases classified elsewhere

16.93

53.30

1.3

1.0

28.45

35.67

u/l

0.21

L04AA Selective immunosuppressants

153

390

3.97

53.03

1.2

1.1

27.08

22.78

u/l

0.51

129

288

Disorders of other endocrine glands

242

811

2.96

52.80

1.2

1.1

34.06

23.08

u/l

0.80

179

627

Persons encountering health services in other circumstances, wide

549

1337

2.14

51.96

1.2

1.1

28.57

22.89

u/l

0.76

382

1073

IBD patients in KELA-register

146

365

4.04

51.93

1.1

21.98

24.48

u/l

0.11

124

279

Disorders of parathyroid gland

153

392

3.90

51.56

1.2

1.1

34.26

24.87

u/l

0.39

114

288

Reimbursement for rheumatic diseases

311

1232

2.53

50.57

1.1

23.10

26.30

u/l

0.49

243

955

Primary biliary cholangitis (PBC)

15.33

50.56

1.1

1.0

27.36

33.61

u/l

0.21

Bacterial Sepsis

238

723

2.95

50.50

1.1

46.40

25.58

u/l

2.20

176

525

Implicit bacterial Sepsis

218

657

3.07

49.84

1.1

49.79

24.38

u/l

2.72

158

478

L04AX Other immunosuppressants

294

1147

2.58

49.61

1.2

1.1

24.05

24.49

u/l

0.03

244

883

Any event in cancer register

429

1122

2.28

48.96

1.2

1.1

30.35

22.39

u/l

1.17

346

845

Inflammatory bowel disease, strict (require KELA)

146

381

3.87

48.96

1.1

21.98

24.41

u/l

0.10

124

292

ILD medications: azathioprine

102

202

5.11

48.61

1.2

1.1

29.21

25.59

u/l

0.11

145

Sub-endpoint used in defining T1D endpoints

168

477

3.49

48.28

1.2

1.1

39.07

23.87

u/l

1.28

119

366

Persons encountering health services for specific procedures and health care

490

1430

2.13

48.25

1.2

1.1

32.93

21.54

u/l

2.28

372

1102

Hernia of abdominal wall, postoperative

167

5.56

48.25

1.2

1.1

37.33

25.58

u/l

0.38

Hyperparathyroidism

138

345

4.01

48.24

1.2

1.1

29.10

25.23

u/l

0.15

105

252

Noninfective enteritis and colitis

246

890

2.78

48.12

1.1

23.02

25.19

u/l

0.13

205

680

Polyarthropathies

347

949

2.45

47.92

1.2

1.1

31.29

24.06

u/l

0.74

276

729

Diseases of oesophagus, stomach and duodenum

489

1409

2.12

47.14

1.1

27.04

24.06

u/l

0.37

395

1058

Inflammatory bowel disease

181

562

3.25

46.57

1.1

21.05

24.63

u/l

0.20

154

428

Azathioprine

102

210

4.91

46.49

1.2

1.1

29.21

24.56

u/l

0.15

154

5-aminosalicylic acid

128

317

4.07

46.16

1.1

24.42

21.85

u/l

0.09

105

231

General symptoms and signs

486

1154

2.12

44.58

1.1

32.35

21.69

u/l

1.75

378

887

Hypertensive diseases (excluding secondary)

268

574

2.73

44.03

1.2

1.1

19.69

17.14

u/l

0.45

198

464

Osteopathies and chondropathies

281

1073

2.50

44.00

1.2

1.1

32.32

24.68

u/l

0.78

219

823

Condition for Implicit Sepsis (Organ dysfunction codes)

388

1287

2.20

43.02

1.1

34.91

22.93

u/l

1.99

293

977

Metabolic disorders

442

1302

2.12

42.96

1.2

1.1

33.81

22.02

u/l

2.13

327

1006

Complications of surgical and medical care, not elsewhere classified

444

1542

2.07

42.29

1.2

1.1

28.47

24.11

u/l

0.69

358

1167

Diabetic retinopathy, strict definition

132

306

3.84

42.13

1.2

1.1

39.32

36.00

u/l

0.14

244

Hypertensive diseases

375

942

2.26

41.73

1.2

1.1

27.11

20.44

u/l

0.82

280

741

Ulcer of lower limb, not elsewhere classified

211

4.66

41.46

1.2

1.1

47.85

34.58

u/l

0.53

154

Ulcerative colitis

142

408

3.51

41.40

1.2

1.1

23.49

24.03

u/l

0.02

120

311

Hypertension

374

942

2.26

41.35

1.2

1.1

27.12

20.44

u/l

0.81

279

741

Hypothyroidism and >3 levothyroxin purchases

111

130

4.93

41.27

1.2

37.58

10.49

u/l

1.15

104

Hypothyroidism, levothyroxine purchases

111

130

4.93

41.27

1.2

37.58

10.49

u/l

1.15

104

Hypothyroidism (congenital or acquired)

111

130

4.93

41.20

1.2

37.58

10.49

u/l

1.15

104

Heart failure and antihypertensive medication

144

254

3.77

41.09

1.2

1.1

41.78

24.03

u/l

1.53

107

195

Hypertension, essential

363

929

2.24

39.57

1.2

1.1

28.46

20.62

u/l

0.95

269

729

Presence of other functional implants

285

835

2.43

39.45

1.2

1.1

24.24

29.80

u/l

0.84

223

615

Insulin, fast-acting (human)

184

4.83

39.42

1.3

1.1

43.54

21.20

u/l

1.07

142

Heart failure,strict

245

683

2.60

39.24

1.2

1.1

35.85

27.17

u/l

0.94

180

501

Abnormal findings on diagnostic imaging and in function studies, without diagnosis

304

1246

2.27

38.44

1.2

1.1

32.70

25.42

u/l

0.99

254

929

Oedema, not elsewhere classified

168

559

3.01

38.14

1.2

1.1

28.90

23.25

u/l

0.46

134

425

UC patients in KELA-register ( KELA 208 prior to 1994, or ICD K51)

109

280

3.93

37.49

1.2

1.1

13.38

24.35

u/l

3.24

220

Certain infectious and parasitic diseases

430

1043

2.07

37.43

1.1

31.04

20.73

u/l

2.10

345

791

Ulcerative colitis (strict definition, require KELA)

103

256

4.06

37.08

1.2

1.1

13.16

24.74

u/l

3.29

204

Ulcerative colitis (strict definition, require KELA, min 2 HDR)

100

244

4.14

36.91

1.2

1.1

12.86

24.51

u/l

3.12

193

Abnormal results of function studies

127

5.61

36.89

1.2

1.1

33.81

25.45

u/l

0.36

Oxycodone

186

654

2.77

36.06

1.2

1.1

44.71

23.05

u/l

2.97

145

482

Cholelithiasis, broad definition with cholecystitis

390

1307

2.05

35.95

1.1

22.37

24.18

u/l

0.32

293

1005

Osteoporosis

150

469

3.08

35.00

1.1

33.49

25.69

u/l

0.44

120

341

Other diseases of blood and blood-forming organs, wide

130

394

3.33

34.97

1.2

1.1

39.88

25.36

u/l

1.29

294

General examination and investigation of persons without complaint and reported diagnosis

294

674

2.33

34.51

1.1

28.30

23.38

u/l

0.35

186

528

Cholangitis (primary sclerosing, PSC)

6.68

34.50

1.2

32.87

30.39

u/l

0.10

Unspecified kidney failure

121

5.53

34.39

1.1

32.53

34.37

u/l

0.07

Crohn disease

177

4.57

33.54

1.1

28.26

23.17

u/l

0.13

138

Other retinal disorders

289

1057

2.21

33.20

1.2

1.1

32.26

25.89

u/l

0.75

216

791

Influenza and pneumonia

440

1515

1.92

33.18

1.2

1.1

29.78

22.65

u/l

1.68

330

1175

Acute tubulo-interstitial nephritis

268

1058

2.26

33.17

1.2

1.1

30.40

21.10

u/l

2.08

196

792

Budesonide

196

4.33

32.93

1.2

1.1

23.72

24.68

u/l

0.05

144

Cholelithiasis

372

1299

2.02

32.89

1.2

1.1

20.09

24.29

u/l

1.16

280

999

Gastro-oesophageal reflux disease

308

1290

2.12

32.81

1.1

22.85

25.10

u/l

0.26

256

966

Finngen Rheumatological endpoints

401

1151

1.99

32.71

1.1

31.02

22.31

u/l

1.14

325

878

Other disorders of skin and subcutaneous tissue, not elsewhere classified

228

4.04

32.48

1.2

1.1

32.32

26.77

u/l

0.37

165

Diseases of the skin and subcutaneous tissue

421

1073

1.97

32.34

1.2

1.1

24.50

24.06

u/l

0.05

332

802

Other disorders of skin and subcutaneous tissue

315

1389

2.09

32.26

1.1

31.76

24.75

u/l

1.00

247

1059

Other disorders of fluid, electrolyte and acid-base balance

156

531

2.85

32.02

1.2

1.1

30.72

26.06

u/l

0.57

124

392

Complications of medical and surgical care

326

1521

2.04

31.77

1.1

30.45

24.23

u/l

0.81

270

1142

Disorders of thyroid, IBD co-morbidities

169

4.12

31.70

1.2

1.1

19.26

16.62

u/l

0.18

132

Hypothyroidism, drug reimbursement

5.29

31.66

1.2

18.11

11.92

u/l

0.85

Ulcerative colitis, NAS

200

4.19

31.22

1.2

1.1

14.57

25.51

u/l

2.22

155

Diabetes, insuline treatment (Kela reimbursement), excluding more controls

416

1326

1.92

31.21

1.1

34.04

21.67

u/l

2.50

320

1021

Chronic periapical parodontitis

116

352

3.32

31.19

1.2

1.1

38.90

32.30

u/l

0.29

283

Diabetes mellitus

436

1380

1.89

31.01

1.1

34.42

21.13

u/l

2.78

336

1065

Diabetes, varying definitions

434

1378

1.89

30.71

1.1

34.56

21.12

u/l

2.82

335

1063

Hypothyroidism, strict autoimmune

293

902

2.16

30.60

1.2

1.1

21.84

23.92

u/l

0.26

226

693

COPD/asthma/ILD related pneumonia or pneumonia derived septicaemia

387

1246

1.95

30.58

1.2

1.1

28.82

24.38

u/l

0.75

293

957

387

1246

1.95

30.58

1.2

1.1

28.82

24.38

u/l

0.75

293

957

Dentinal caries

118

365

3.24

30.45

1.2

1.1

35.82

31.25

u/l

0.20

292

Abnormalities of breathing

374

1125

1.98

30.43

1.1

23.45

24.40

u/l

0.12

288

854

Nutritional anaemias

227

959

2.31

30.41

1.2

1.1

37.79

25.78

u/l

0.81

174

727

Other heart diseases

213

570

2.48

30.40

1.2

1.1

35.19

17.16

u/l

1.78

169

461

All pneumoniae

416

1530

1.88

30.16

1.2

1.1

31.67

23.06

u/l

1.88

313

1184

Pneumonia, organism unspecified

379

1421

1.94

30.14

1.2

1.1

30.91

23.55

u/l

1.41

287

1094

Gout

133

403

3.03

30.02

1.1

42.29

29.38

u/l

0.70

107

283

Type 2 diabetes, wide definition

354

1161

1.99

29.97

1.1

36.73

22.21

u/l

2.63

274

884

Dermatitis and eczema

446

1594

1.84

29.81

1.2

1.1

24.99

24.74

u/l

0.03

354

1208

Implicit viral Sepsis

100

286

3.53

29.51

1.2

1.1

40.03

24.75

u/l

1.13

213

Pneumonias (Asthma/COPD co-morbidities)

411

1527

1.87

29.27

1.2

1.1

30.51

23.39

u/l

1.45

310

1181

Viral Sepsis

100

288

3.50

29.21

1.2

1.1

40.03

24.64

u/l

1.15

215

Diabetes, insulin treatment (Kela reimbursement)

428

1418

1.85

28.78

1.1

33.68

22.22

u/l

2.28

328

1094

Disorders of choroid and retina

348

1302

1.95

28.50

1.2

1.1

30.16

25.88

u/l

0.51

262

985

Endocrine, nutritional and metabolic diseases

305

735

2.12

28.40

1.2

1.1

20.92

18.74

u/l

0.31

223

582

Heart failure, strict

253

830

2.20

28.39

1.2

1.1

34.91

28.05

u/l

0.72

187

611

Gout, FINNGEN

133

464

2.89

28.20

1.1

42.29

30.48

u/l

0.62

107

335

Diabetic retinopathy, excluding more controls

148

284

2.96

27.94

1.2

1.1

38.65

29.06

u/l

0.60

110

216

Sleep disorders (combined)

415

1481

1.84

27.90

1.1

21.23

26.47

u/l

1.07

333

1123

Dental caries

123

410

2.99

27.75

1.2

1.1

34.38

31.07

u/l

0.15

330

All-cause Heart Failure

249

821

2.20

27.70

1.2

1.1

35.10

28.26

u/l

0.71

185

605

Nausea and vomiting

127

429

2.93

27.58

1.2

1.1

38.65

26.04

u/l

0.88

107

326

Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity

117

5.03

27.25

1.2

1.1

23.46

26.91

u/l

0.25

Diabetes medication

425

1428

1.81

26.79

1.1

33.51

21.36

u/l

2.56

329

1098

Disorders of mineral metabolism

123

4.87

26.68

1.2

1.1

68.01

23.13

u/l

1.35

Ulcerative colitis (strict definition, all Crohn cases excluded)

202

3.90

26.65

1.2

1.1

14.42

24.32

u/l

1.85

157

Sleep apnoea

389

1435

1.84

26.48

1.1

20.25

27.40

u/l

1.90

310

1089

Sleep apnoea, including avohilmo

406

1448

1.83

26.48

1.1

19.76

27.31

u/l

2.17

326

1099

Other heart diseases, wide

378

1258

1.87

26.32

1.2

1.1

31.99

21.81

u/l

1.49

301

966

Iron deficiency anaemia

189

805

2.34

26.08

1.1

39.40

25.60

u/l

0.77

144

612

Disorders of lens

303

955

2.01

26.06

1.2

1.1

31.22

24.26

u/l

0.68

231

720

Secondary uncertain malignant neoplasm, excluding all cancers (controls excluding all cancers)

177

644

2.43

25.93

1.2

1.1

59.29

21.58

u/l

3.32

145

473

Diseases of pulp and periapical tissues

162

656

2.48

25.62

1.2

1.1

32.72

29.26

u/l

0.20

133

525

Other disorders of kidney and ureter

199

3.86

25.62

1.3

1.1

26.75

30.56

u/l

0.25

149

ICD-8 DM (Sub-endpoint used for defining DM endpoints)

7.41

25.50

1.2

1.1

37.88

23.54

u/l

0.57

Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

266

1318

2.02

25.44

1.1

32.04

24.68

u/l

0.84

218

990

Pneumonia (excl. viral and due to other infectious organisms not elsewhere classified)

394

1535

1.81

25.41

1.2

1.1

30.44

23.66

u/l

1.32

298

1186

Complications of procedures, not elsewhere classified

330

1514

1.89

25.41

1.1

26.90

24.34

u/l

0.29

261

1142

Mucosal proctocolitis

166

4.13

25.21

1.2

1.1

15.92

24.80

u/l

1.30

127

Amputation

138

4.47

24.96

1.2

1.1

71.72

28.67

u/l

1.26

103

Cardiovascular diseases (excluding rheumatic etc)

243

649

2.17

24.95

1.2

1.1

20.41

16.08

u/l

0.93

183

522

Opioids

398

1148

1.82

24.76

1.2

1.1

26.72

19.51

u/l

1.66

314

871

Type 2 diabetes

404

1338

1.80

24.67

1.1

31.16

21.65

u/l

1.91

314

1031

Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

237

3.54

24.66

1.1

47.06

28.83

u/l

0.94

177

Erysipelas

221

941

2.15

24.66

1.1

34.18

22.19

u/l

1.41

165

695

Other diseases of intestines

417

1364

1.78

24.60

1.2

1.1

29.15

23.61

u/l

0.69

345

1027

Other noninfective gastroenteritis and colitis

118

416

2.85

24.57

1.2

1.1

22.44

27.83

u/l

0.30

315

Gout, strict definition

263

3.38

24.36

1.1

36.46

30.70

u/l

0.24

194

Bleeding

339

1331

1.86

24.05

1.2

1.1

34.76

25.02

u/l

1.06

245

1021

Diabetic retinopathy

171

443

2.46

23.68

1.2

1.1

36.30

33.13

u/l

0.17

125

341

Other soft tissue disorders, not elsewhere classified

360

1218

1.83

23.56

1.2

1.1

24.13

24.60

u/l

0.05

278

930

Benzodiazepine use

398

1616

1.76

23.44

1.1

23.44

25.27

u/l

0.17

306

1237

Peripheral artery operations in Hilmo

189

3.79

23.37

1.2

1.1

66.94

28.44

u/l

1.36

133

Disorders of the thyroid gland

379

1389

1.79

23.27

1.2

1.1

25.22

24.89

u/l

0.02

284

1081

Glomerulonephritis

147

4.20

23.06

1.2

1.1

20.46

25.36

u/l

0.43

109

Agranulocytosis

183

3.81

22.89

1.2

1.1

33.49

23.30

u/l

0.57

135

Osteomyelitis

5.38

22.80

1.2

1.1

85.31

31.00

u/l

1.14

Tramadol

318

1091

1.88

22.79

1.1

32.55

20.14

u/l

2.60

238

830

Other and unspecified disorders of skin and subcutaneous tissue

5.13

22.62

1.3

1.1

26.37

22.20

u/l

0.27

Other and unspecified iron deficiency

146

598

2.45

22.59

1.1

39.25

25.52

u/l

0.61

109

449

Cirrhosis of liver, NAS

5.81

22.47

1.1

45.78

23.45

u/l

1.82

Noninfectious colitis NAS

195

3.67

22.38

1.2

1.1

27.20

26.62

u/l

0.02

145

Dermatitis

253

1296

1.96

22.34

1.2

1.1

29.56

25.72

u/l

0.32

197

987

Vitreous haemorrhage

155

4.05

22.33

1.3

1.1

35.42

30.58

u/l

0.20

113

Acute peritonitis

5.02

22.08

1.2

1.1

26.13

26.04

u/l

0.00

Chronic pancreatitis

174

3.83

22.08

1.1

41.26

30.34

u/l

0.43

133

Amputation of toe

103

4.83

22.00

1.2

1.1

73.97

30.11

u/l

0.92

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

245

1257

1.96

21.53

1.1

31.09

25.24

u/l

0.57

200

956

Disorders of calcium metabolism

4.97

21.35

1.1

79.05

21.58

u/l

1.32

Constipation

356

1451

1.76

21.26

1.1

23.52

25.74

u/l

0.20

261

1115

Diseases of the digestive system

189

886

2.14

21.17

1.2

1.1

41.56

25.78

u/l

0.95

136

666

Other and unspecified dermatitis

214

1056

2.03

21.06

1.2

1.1

24.42

24.55

u/l

0.01

171

817

Diseases of arteries, arterioles and capillaries (FINNGEN)

116

295

2.76

20.95

1.2

1.1

61.93

17.49

u/l

2.50

231

Hyperkalaemia

5.49

20.75

1.2

1.1

26.68

26.56

u/l

0.00

Pain in limb

303

1199

1.83

20.66

1.2

1.1

21.08

24.77

u/l

0.62

227

918

Diarrhoea and gastroenteritis of presumed infectious origin

270

1316

1.87

20.45

1.2

1.1

32.20

23.31

u/l

1.28

207

1000

Systemic connective tissue disorders

160

715

2.25

20.37

1.1

30.67

23.48

u/l

0.60

123

551

Gastrointestinal diseases

209

491

2.14

20.07

1.2

1.1

17.92

20.84

u/l

0.38

167

352

Neoplasms

253

690

1.97

19.99

1.2

1.1

30.67

19.77

u/l

1.07

202

513

Gout, unspecified

313

2.93

19.96

1.1

42.22

30.02

u/l

0.48

229

Other Crohn's disease

4.84

19.88

1.1

40.93

25.58

u/l

0.23

Gout, idiopatic and unspecified

107

404

2.67

19.69

1.1

41.70

29.94

u/l

0.53

300

Dyspnoea

348

1550

1.72

19.57

1.1

26.30

25.07

u/l

0.16

270

1183

Crohn's disease of large intestine

5.43

19.50

1.1

44.70

25.69

u/l

0.24

Infections of the skin and subcutaneous tissue

220

1124

1.96

19.40

1.2

1.1

32.88

24.68

u/l

0.63

169

855

Hydronephrosis

136

4.01

19.28

1.1

44.43

26.54

u/l

0.69

Hypothyroidism, other/unspecified

347

1327

1.73

19.22

1.1

24.12

24.78

u/l

0.05

265

1036

Cholangitis (primary sclerosing, PSC), with reimbursement 202

8.85

19.00

1.2

1.1

36.17

33.05

u/l

0.07

Cardiac arrhythmias

238

814

1.94

18.93

1.1

25.41

17.60

u/l

1.54

184

641

Symptoms and signs involving the digestive system and abdomen

383

1129

1.70

18.87

1.1

26.97

24.44

u/l

0.31

304

847

Deposits [accretions] on teeth

4.72

18.67

1.2

1.1

26.47

31.26

u/l

0.24

Parasetamol

281

773

1.86

18.59

1.2

25.21

21.29

u/l

0.54

215

607

Osteoporosis with pathological fracture (FG)

102

4.47

18.48

1.2

1.1

42.24

30.63

u/l

0.24

Sulfasalazine

124

522

2.39

18.18

1.1

21.71

23.59

u/l

0.13

395

Diseases of peritoneum

170

3.57

18.15

1.2

1.1

23.74

26.77

u/l

0.23

127

Fall on same level

432

1495

1.62

17.99

1.2

1.1

28.43

22.97

u/l

0.85

331

1145

Other medical care

160

737

2.13

17.78

1.2

1.1

53.00

25.09

u/l

1.69

102

549

Chronic ulcer of skin, not elsewhere classified

4.66

17.74

1.1

43.91

35.41

u/l

0.25

Spondyloarthritis

253

3.02

17.69

1.1

27.47

28.25

u/l

0.03

189

Atrial fibrillation and flutter

139

390

2.34

17.69

1.1

31.77

18.02

u/l

1.66

101

314

COPD/asthma related infections

408

1247

1.64

17.58

1.2

1.1

23.90

24.38

u/l

0.06

321

957

COPD/asthma/ILD related infections

408

1247

1.64

17.58

1.2

1.1

23.90

24.38

u/l

0.06

321

957

Other disorders of urethra and urinary system

285

1212

1.77

17.46

1.2

1.1

21.15

25.13

u/l

0.69

208

953

Senile cataract

257

866

1.85

17.46

1.2

1.1

28.65

24.97

u/l

0.27

198

650

Vocal cord dysfunction

169

3.43

17.42

1.1

35.49

17.56

u/l

0.38

132

Antihypertensive medication - note that there are other indications

201

543

2.03

17.42

1.2

1.1

19.42

20.25

u/l

0.09

151

421

Follow-up examination after treatment for conditions other than malignant neoplasms

181

574

2.07

17.31

1.2

1.1

17.25

23.58

u/l

1.72

153

454

Hypothyreosis and Thyroxine purchase for inclusion criteria

356

1414

1.67

17.23

1.2

1.1

23.78

24.64

u/l

0.07

271

1098

Secondary malignant neoplasm of other and unspecified sites, excluding all cancers (controls excluding all cancers)

370

2.61

17.03

1.2

1.1

60.97

22.62

u/l

1.89

275

Obesity due to excess calories

183

924

1.99

17.01

1.1

20.04

26.06

u/l

0.92

140

728

Medical observation and evaluation for suspected diseases and conditions

247

674

1.88

17.00

1.2

1.1

28.17

23.38

u/l

0.51

199

528

Exposure to unspecified factor

356

1682

1.65

16.98

1.1

30.82

23.31

u/l

1.14

276

1286

Other disorders of teeth and supporting structures

367

2.60

16.78

1.1

37.64

29.30

u/l

0.38

292

Arthropathies in other diseases classified elsewhere

5.88

16.69

1.4

1.0

50.12

25.06

u/l

0.43

Amputation of foot

7.85

16.62

1.1

1.2

41.22

32.30

u/l

0.27

Malaise and fatigue

183

768

1.99

16.59

1.1

31.62

21.86

u/l

1.48

145

586

Infections, IBD-co-morbidities

149

3.29

16.55

1.1

43.78

18.63

u/l

1.47

116

Other special examinations and investigations of persons without complaint or reported diagnosis

247

674

1.86

16.37

1.1

31.63

23.38

u/l

0.57

182

528

Intestinal infectious diseases

343

1629

1.64

16.26

1.1

32.03

23.23

u/l

1.42

266

1241

Complications of internal orthopaedic prosthetic devices, implants and grafts

104

427

2.45

16.19

1.2

1.1

25.78

30.04

u/l

0.42

304

Crohn disease (strict definition, require KELA)

4.40

16.15

1.1

44.59

21.48

u/l

0.33

IBD (strict) with PSC

12.83

16.13

1.2

24.82

5.78

u/l

—

Other and unspecified polyneuropathies, also in other diseases

324

2.67

16.00

1.2

1.1

45.03

30.09

u/l

0.59

243

Colitis, primary sclerosing

9.01

15.99

1.3

1.1

29.60

13.65

u/l

0.96

Seropositive rheumatoid arthritis

112

477

2.35

15.98

1.1

25.67

22.89

u/l

0.33

365

Codeine

344

1140

1.66

15.93

1.2

1.1

22.34

19.59

u/l

0.54

266

866

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

126

264

2.40

15.84

1.1

23.44

16.56

u/l

0.95

210

Cerebrovascular diseases (FINNGEN)

131

417

2.26

15.83

1.1

53.99

17.15

u/l

1.94

337

Abnormal findings on diagnostic imaging of lung

185

937

1.93

15.75

1.2

1.1

33.90

25.98

u/l

0.90

158

689

Symptoms and signs involving the circulatory and respiratory systems

367

1130

1.63

15.51

1.1

20.91

24.33

u/l

0.65

290

857

Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

4.26

15.51

1.1

44.59

21.48

u/l

0.33

Primary_lymphoid and hematopoietic malignant neoplasms

376

2.51

15.47

1.1

42.02

22.73

u/l

1.61

273

Crohn's disease NAS

4.42

15.44

1.1

47.97

25.87

u/l

0.29

Hypothyroidism, strict autoimmune, 3 medication purchases required

322

1332

1.65

15.30

1.2

1.1

22.77

24.65

u/l

0.24

246

1042

Biological medication for rheuma

248

2.88

15.26

1.2

1.1

21.36

21.06

u/l

0.01

197

Continuous positive airway pressure

238

2.80

15.25

1.1

18.04

18.86

u/l

0.09

185

Other diseases of pancreas

101

4.10

15.16

1.1

1.2

54.99

32.01

u/l

0.57

Cardiovascular diseases

195

549

1.94

14.98

1.2

1.1

20.93

16.12

u/l

0.87

146

434

Other diseases of urinary system

385

1368

1.59

14.96

1.2

1.1

22.08

25.35

u/l

0.57

274

1072

Pain in throat and chest

302

1101

1.68

14.96

1.1

24.58

24.78

u/l

0.02

238

835

Pure hypercholesterolaemia

273

1070

1.72

14.89

1.1

32.87

23.23

u/l

1.24

206

818

Other diseases of biliary tract

125

3.72

14.86

1.3

1.1

25.63

32.68

u/l

0.43

Diseases of the ear and mastoid process

428

1397

1.55

14.84

1.1

24.42

24.15

u/l

0.03

352

1050

Other functional intestinal disorders

176

875

1.92

14.79

1.1

27.52

24.70

u/l

0.13

130

657

Drug-induced neutropenia

121

3.77

14.77

1.2

1.1

38.90

20.33

u/l

0.77

Rheumatoid arthritis

141

618

2.08

14.71

1.1

24.62

25.90

u/l

0.15

103

485

Other nutritional deficiencies

239

1344

1.74

14.71

1.1

19.29

24.63

u/l

1.09

186

1044

Cellulitis

351

2.52

14.61

1.2

1.1

41.77

25.98

u/l

0.76

263

Heart failure and bmi 25plus

143

470

2.11

14.52

1.1

29.90

22.70

u/l

1.15

107

377

Other diseases of pleura

172

793

1.93

14.44

1.1

38.22

27.12

u/l

1.25

130

580

Abdominal and pelvic pain

360

1129

1.61

14.37

1.1

23.83

24.44

u/l

0.06

271

847

Ulcerative rectosigmoiditis

110

3.85

14.30

1.2

1.1

10.54

25.07

u/l

2.54

Disorders of lipoprotein metabolism and other lipidaemias

305

1165

1.65

14.22

1.2

1.1

33.39

23.33

u/l

1.48

222

892

Hypo-osmolality and hyponatraemia

292

2.65

14.10

1.2

1.1

28.14

28.73

u/l

0.04

221

Cutaneous abscess, furuncle and carbuncle

419

2.35

14.01

1.2

1.1

23.55

24.60

u/l

0.06

321

Symptoms and signs concerning food and fluid intake

135

3.50

13.97

1.0

1.1

17.82

22.42

u/l

0.40

101

Tumor necrosis factor alpha inhibitors

212

2.94

13.88

1.2

1.1

20.74

20.13

u/l

0.02

172

Hyperlipidaemia, other/unspecified

147

699

2.00

13.84

1.2

1.1

28.30

23.77

u/l

0.47

102

512

Benign neoplasm of colon, rectum, anus and anal canal

189

726

1.87

13.81

1.1

27.23

21.21

u/l

0.83

158

527

Polyneuropathies and other disorders of the peripheral nervous system

373

2.43

13.81

1.2

1.1

43.59

28.15

u/l

0.68

280

Depression medications

140

2.85

13.77

1.2

19.99

10.27

u/l

1.71

112

Crohn's disease of small intestine

4.11

13.73

1.1

12.70

23.50

u/l

1.44

Other necrotizing vasculopathies

105

3.85

13.60

1.1

23.20

24.73

u/l

0.08

Episodal and paroxysmal disorders

397

1318

1.55

13.60

1.1

26.01

25.00

u/l

0.09

312

1006

Hepatic failure, not elsewhere classified

5.51

13.56

1.0

58.81

27.58

u/l

1.16

Crohn disease (strict definition, require KELA, min 2 HDR)

4.07

13.54

1.1

48.29

21.48

u/l

0.36

Symptoms and signs involving the urinary system

281

1325

1.64

13.45

1.1

32.67

23.42

u/l

1.18

216

1006

Iron deficiency anaemia secondary to blood loss (chronic)

266

2.69

13.43

1.2

1.1

33.65

28.47

u/l

0.17

199

Nephrotic syndrome

6.16

13.43

1.3

1.1

20.61

26.24

u/l

0.22

Psoriasis

117

549

2.14

13.39

1.1

26.99

24.25

u/l

0.12

418

Other necrotizing vasculopathies (FG)

4.30

13.38

1.1

24.66

31.75

u/l

0.37

Fitting and adjustment of other devices

133

607

2.05

13.35

1.1

31.63

27.61

u/l

0.21

448

Obesity and other hyperalimentation

226

1306

1.72

13.29

1.1

19.95

24.17

u/l

0.73

177

1015

Cholecystectomy

271

1463

1.64

13.22

1.1

19.90

27.13

u/l

1.49

206

1125

Other diseases of the digestive system

121

579

2.10

13.16

1.2

1.1

42.82

29.38

u/l

0.51

435

Other cataract

168

690

1.89

13.05

1.2

1.1

37.01

25.49

u/l

0.96

130

514

Other systemic involvement of connective tissue (FG)

102

455

2.24

13.01

1.1

36.45

23.70

u/l

0.67

345

Obesity

224

1301

1.71

12.98

1.1

19.94

24.23

u/l

0.74

176

1011

Purpura and other haemorrhagic conditions

210

2.88

12.92

1.2

1.1

28.79

29.57

u/l

0.05

157

Ulcerative ileocolitis

4.74

12.85

1.1

1.2

60.87

27.61

u/l

0.32

Familial hypercholesterolemia, with ischemic heart disease

148

3.27

12.84

1.2

1.1

56.06

32.05

u/l

0.55

109

Glucagon-like peptide-1 (GLP-1) analogues

214

1015

1.74

12.81

1.1

32.89

24.50

u/l

0.89

173

763

Exclusions for E4_PCOS_BROAD

261

2.66

12.81

1.2

1.1

47.69

25.26

u/l

0.50

201

Corns and callosities

3.91

12.53

1.4

1.1

58.83

22.27

u/l

0.68

Other inflammatory liver diseases

3.91

12.53

1.2

1.1

27.94

21.89

u/l

0.42

Coagulation defects, purpura and other haemorrhagic conditions

317

2.47

12.52

1.2

1.1

36.07

26.06

u/l

0.40

239

Gonarthrosis [arthrosis of knee](FG)

276

994

1.64

12.43

1.1

27.03

23.76

u/l

0.25

208

753

Benign neoplasms

228

748

1.73

12.40

1.2

1.1

33.48

20.41

u/l

1.16

179

555

Chronic periodontitis

255

2.64

12.33

1.3

1.1

27.89

32.10

u/l

0.26

200

Postmenopausal osteoporosis with pathological fracture

3.94

12.28

1.3

1.1

45.09

22.43

u/l

0.41

Diabetic neuropathy

215

2.80

12.26

1.2

1.1

57.23

32.59

u/l

0.76

174

Syncope and collapse

153

719

1.89

12.21

1.1

31.03

21.86

u/l

0.99

110

543

All influenza

401

2.28

12.19

1.2

1.1

32.33

25.03

u/l

0.57

302

Ascites

3.83

12.17

1.3

1.1

89.62

26.93

u/l

1.56

Thrombocytopenia, unspecified

109

3.62

12.15

1.3

1.1

27.03

32.16

u/l

0.28

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

163

551

1.88

12.00

1.2

1.1

23.89

17.43

u/l

1.14

128

448

Other diseases of hard tissues of teeth

229

1018

1.68

11.96

1.1

21.90

25.98

u/l

0.67

168

801

Diseases of the eye and adnexa

281

866

1.63

11.95

1.1

23.56

22.86

u/l

0.05

217

680

Pain in joint

207

791

1.74

11.88

1.2

1.1

18.12

25.80

u/l

1.73

162

610

Injuries to the hip and thigh

165

833

1.82

11.73

1.2

1.1

34.76

25.71

u/l

0.67

121

633

Intracranial trauma

194

830

1.75

11.73

1.1

24.79

22.30

u/l

0.23

135

648

Valvular heart disease excluding rheumatic fever

170

683

1.82

11.72

1.2

1.1

40.63

23.68

u/l

1.18

132

503

Thyrotoxicosis, other and/or unspecified

358

2.33

11.72

1.1

14.18

23.61

u/l

2.33

273

Benign neoplasm: Colon

164

686

1.84

11.68

1.2

1.1

28.17

21.58

u/l

0.81

138

493

Enterocolitis due to Clostridium difficile

157

3.08

11.67

1.1

45.36

29.51

u/l

0.54

109

Cough

154

801

1.85

11.67

1.1

22.01

27.98

u/l

0.61

128

614

Non-ischemic cardiomyopathy

116

464

2.06

11.66

1.1

28.22

25.69

u/l

0.25

337

Unspecified urinary incontinence

168

3.01

11.63

1.1

26.60

23.23

u/l

0.19

125

Hypokalaemia

184

2.90

11.62

1.2

1.1

35.80

29.41

u/l

0.38

139

Diseases of oral cavity, salivary glands and jaws

329

1088

1.55

11.62

1.1

21.72

26.66

u/l

0.79

238

854

Non-rheumatic valve diseases

169

679

1.82

11.62

1.2

1.1

40.14

23.78

u/l

1.11

131

499

Peripheral artery disease

165

730

1.83

11.61

1.2

1.1

47.25

27.02

u/l

1.59

125

530

Other reaction to severe stress, and adjustment disorders

133

691

1.93

11.57

1.2

1.1

45.24

19.97

u/l

1.21

539

AV-block

248

2.54

11.51

1.1

34.12

32.49

u/l

0.08

175

Recurrent or chronic depression

153

591

1.88

11.50

1.2

1.1

25.82

21.27

u/l

0.35

115

478

Thyroiditis, ILD-related definition

169

2.98

11.50

1.2

1.1

21.42

23.18

u/l

0.07

126

Papulosquamous disorders

150

813

1.85

11.47

1.1

25.62

26.17

u/l

0.03

120

625

Other antidepressants

369

1278

1.51

11.47

1.1

22.30

26.63

u/l

0.81

277

987

Diseases of arteries, arterioles and capillaries

236

1071

1.65

11.45

1.2

1.1

46.72

23.27

u/l

2.23

188

792

Nerve, nerve root and plexus disorders

376

1589

1.49

11.39

1.2

1.1

24.14

24.81

u/l

0.08

288

1221

Malignant neoplasm of prostate, excluding all cancers (controls excluding all cancers)

255

2.27

11.36

1.2

1.1

20.66

24.13

u/l

0.34

192

Atrial fibrillation and flutter with reimbursement

105

312

2.17

11.36

1.1

27.07

17.95

u/l

1.40

243

Hard cardiovascular diseases

288

1175

1.58

11.35

1.1

50.06

22.15

u/l

3.16

204

921

Gastroduodenal ulcer

458

2.14

11.33

1.1

42.82

32.71

u/l

0.52

322

Respiratory diseases principally affecting the interstitium, IBD co-morbidites

101

3.30

11.30

1.2

1.1

34.90

20.24

u/l

0.73

Excluding asthma or asthma-COPD overlap

286

899

1.60

11.27

1.2

1.1

21.96

22.81

u/l

0.10

232

664

Intestinal stricture

117

590

1.99

11.12

1.2

1.1

42.61

27.54

u/l

0.78

445

Disorders of vitreous body

191

1099

1.71

11.06

1.2

1.1

27.16

26.37

u/l

0.06

142

840

Codeine or tramadol medication

402

1521

1.47

11.02

1.2

1.1

22.27

25.12

u/l

0.56

309

1163

Problems related to lifestyle

102

3.55

11.00

1.2

1.1

79.56

21.71

u/l

0.78

Disorders of vitreous body and globe

195

1127

1.69

10.95

1.2

1.1

26.95

26.07

u/l

0.07

146

862

Other specific joint derangements/joint disorders

239

985

1.63

10.93

1.2

1.1

20.92

23.13

u/l

0.30

191

760

GI-bleeding

114

574

1.99

10.89

1.2

1.1

45.45

29.40

u/l

0.58

430

Primary_lymphoid and hematopoietic malignant neoplasms

441

2.14

10.87

1.1

42.02

29.85

u/l

0.78

331

malignant neoplasm of male genital organs, excluding all cancers (controls excluding all cancers)

270

2.20

10.81

1.2

1.1

20.06

23.89

u/l

0.40

205

Other disorders of glucose regulation and pancreatic internal secretion

123

3.28

10.80

1.3

1.1

33.67

22.16

u/l

0.72

Mycoses

101

490

2.07

10.70

1.1

41.15

27.10

u/l

0.87

373

Viral infections characterized by skin and mucous membrane lesions

145

795

1.83

10.69

1.2

1.1

24.77

27.40

u/l

0.23

114

610

Chronic laryngitis and laryngotracheitis

257

2.51

10.62

1.2

1.1

33.28

28.34

u/l

0.10

194

Other arthritis (FG)

111

559

1.99

10.61

1.1

35.65

23.87

u/l

0.45

432

Fracture of femur

422

2.11

10.60

1.1

39.84

30.80

u/l

0.39

310

Rheumatoid arthritis, including avohilmo

150

835

1.80

10.57

1.1

26.18

25.60

u/l

0.06

110

648

Irritable bowel syndrome

106

527

2.02

10.51

1.1

14.02

20.92

u/l

2.11

403

Other/unspecified seropositive rheumatoid arthritis

112

569

1.98

10.47

1.1

25.67

26.27

u/l

0.05

434

Zoster [herpes zoster]

326

2.31

10.46

1.2

1.1

22.02

30.08

u/l

0.59

242

Enlarged lymph nodes

242

2.53

10.38

1.1

42.95

22.11

u/l

1.25

190

Other pulmonary diagnosis

281

899

1.57

10.34

1.2

1.1

21.12

22.81

u/l

0.23

225

664

Sequelae with surgical and medical care as external cause

372

2.22

10.34

1.3

1.1

28.00

26.49

u/l

0.11

277

Paralytic ileus and intestinal obstruction

463

2.08

10.34

1.2

1.1

48.18

27.09

u/l

0.91

332

Exposure to other specified factors

248

1484

1.57

10.31

1.1

27.11

23.99

u/l

0.28

195

1139

Falls/tendency to fall

386

1323

1.46

10.30

1.1

25.75

23.16

u/l

0.31

289

1024

Sequelae of external causes of morbidity and mortality

464

2.08

10.30

1.3

1.1

36.67

26.67

u/l

0.64

346

407

1490

1.44

10.29

1.2

1.1

24.31

24.90

u/l

0.08

314

1140

Other symptoms and signs involving the nervous and musculoskeletal systems

153

864

1.78

10.27

1.1

31.48

25.20

u/l

0.19

694

Fungal Sepsis

4.59

10.26

1.2

1.1

45.06

33.99

u/l

0.17

Mood disorders, excluding more controls

332

1356

1.49

10.18

1.1

24.54

21.83

u/l

0.23

242

1063

Seropositive rheumatoid arthritis, wide

112

575

1.96

10.17

1.1

25.67

26.14

u/l

0.04

438

Neurological diseases, wide definition

200

2.26

10.17

1.2

1.1

24.66

19.12

u/l

0.42

157

COPD differential diagnosis

280

899

1.56

10.16

1.2

1.1

21.97

23.07

u/l

0.14

225

665

ILD differential diagnosis

280

899

1.56

10.16

1.2

1.1

21.97

23.07

u/l

0.14

225

665

Benign neoplasm of other and ill-defined parts of digestive system

281

2.40

10.14

1.1

22.20

24.15

u/l

0.19

205

Familial hypercholesterolemia

263

2.45

10.13

1.2

1.1

54.71

29.30

u/l

0.73

196

Acute pancreatitis

312

2.32

10.12

1.1

59.06

29.21

u/l

0.72

237

Gastric ulcer

300

2.34

10.09

1.1

48.36

34.79

u/l

0.53

211

Other systemic involvement of connective tissue

104

522

2.00

10.07

1.1

36.91

25.33

u/l

0.60

398

Type 2 diabetes, definitions combined, including avohilmo

326

1292

1.50

10.07

1.1

29.73

23.10

u/l

0.92

259

997

Other/unspecified seropositive rheumatoid arthritis (ICD-10)

109

557

1.97

10.04

1.1

25.66

26.00

u/l

0.03

425

Myeloproliferative diseases

140

3.03

9.95

1.1

39.75

26.06

u/l

0.93

100

Anxiety disorders, excluding more controls

286

1244

1.53

9.94

1.2

1.1

32.40

21.57

u/l

0.96

214

979

Diseases of the respiratory system

245

768

1.60

9.86

1.1

22.88

26.59

u/l

0.48

197

572

Multiple myeloma, Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

110

3.30

9.85

1.3

1.1

31.54

26.24

u/l

0.25

Asthma, excluding more controls

248

833

1.59

9.83

1.1

19.73

21.65

u/l

0.28

186

622

Dental caries 3 and operation codes

315

1074

1.51

9.80

1.1

23.44

26.03

u/l

0.29

237

832

Family history of malignant neoplasm

163

2.84

9.78

1.2

1.1

14.69

18.46

u/l

0.52

128

Myeloproliferative diseases (CML excluded)

126

3.12

9.75

1.1

41.54

27.45

u/l

0.86

Dental caries 1 and operation codes

302

1022

1.52

9.72

1.1

23.86

26.11

u/l

0.23

225

795

Other disorders of ear

324

1465

1.48

9.61

1.1

23.30

25.69

u/l

0.32

253

1105

Other (not insulin) diabetes medications

333

1365

1.47

9.60

1.1

29.05

22.20

u/l

1.07

262

1050

Any mental disorder

396

1384

1.43

9.59

1.2

1.1

32.60

21.71

u/l

1.39

293

1080

Thyrotoxicosis with diffuse goitre

246

2.45

9.57

1.2

1.1

15.49

22.85

u/l

1.00

188

Collagenous colitis

138

2.99

9.57

1.1

14.00

23.56

u/l

1.52

Smoking dependency

133

3.03

9.53

1.1

25.14

23.31

u/l

0.08

Mental and behavioural disorders due to tobacco

133

3.03

9.53

1.1

25.14

23.11

u/l

0.09

Other bacterial intestinal infections

283

2.34

9.53

1.1

38.36

27.07

u/l

0.49

211

Malignant neoplasm of breast, ER-negative, excluding all cancers (controls excluding all cancers)

427

2.06

9.46

1.1

15.45

19.52

u/l

0.69

311

Cholecystitis

206

2.59

9.44

1.1

37.39

35.38

u/l

0.07

154

Unspecified haematuria

143

692

1.78

9.41

1.1

25.62

25.24

u/l

0.04

108

513

Depression

323

1517

1.47

9.40

1.1

24.82

24.81

u/l

0.00

230

1187

Ischemic heart diseases

282

1168

1.52

9.38

1.2

1.1

41.20

23.07

u/l

1.89

210

903

malignant neoplasm of male genital organs

126

427

1.88

9.37

1.2

1.1

22.22

34.27

u/l

1.33

329

Thyrotoxicosis

101

516

1.97

9.34

1.1

15.69

24.19

u/l

2.09

397

Asthma, unspecified (mode), excluding more controls

169

784

1.70

9.34

1.1

18.04

21.56

u/l

0.71

124

589

Genitourinary diseases

178

521

1.72

9.33

1.1

28.13

24.38

u/l

0.31

133

398

Type 2 diabetes, definitions combined

322

1305

1.47

9.33

1.1

30.41

21.90

u/l

1.35

258

1004

Persons encountering health services for examination and investigation

218

674

1.62

9.33

1.1

24.72

23.38

u/l

0.15

164

528

Other diseases of anus and rectum

108

565

1.92

9.29

1.1

23.89

26.31

u/l

0.21

411

Non-invasive ventilation

303

2.24

9.28

1.1

32.68

18.57

u/l

1.17

236

Spondylopathies (FG)

197

2.60

9.21

1.1

20.51

22.38

u/l

0.08

147

Other disorders of white blood cells

3.48

9.20

1.1

49.50

24.14

u/l

1.32

Vitamin B12 deficiency anaemia

169

2.74

9.16

1.2

1.1

20.43

29.84

u/l

0.99

123

Oesophageal varices

3.93

9.16

1.1

43.74

28.74

u/l

0.63

Other symptoms and signs involving the digestive system and abdomen

301

2.27

9.14

1.1

29.30

23.15

u/l

0.34

226

Neurotic, stress-related and somatoform disorders

298

1433

1.48

9.11

1.2

1.1

34.22

22.86

u/l

1.02

222

1119

Psoriasis vulgaris

327

2.21

9.11

1.1

26.34

27.00

u/l

0.03

248

Monoclonal gammopathy of undetermined significance (MGUS), excluding all cancers (controls excluding all cancers)

4.01

9.06

1.3

1.1

36.29

29.88

u/l

0.20

Malignant neoplasm of prostate

123

416

1.87

9.05

1.2

1.1

22.64

34.70

u/l

1.28

321

Statin medication

255

929

1.54

9.02

1.1

19.87

24.13

u/l

0.73

192

732

Presence of cardiac and vascular implants and grafts

145

627

1.75

9.00

1.2

1.1

34.68

31.34

u/l

0.25

108

445

Diseases of external ear

116

630

1.85

8.94

1.1

23.51

25.34

u/l

0.17

478

Other specified/unspecified arthritis

512

1.94

8.86

1.1

35.93

24.12

u/l

0.40

406

Type 2 diabetes, strict (exclude DM1)

322

1320

1.46

8.86

1.1

30.41

22.95

u/l

1.10

258

1016

Heart failure and coronary heart disease

115

458

1.88

8.86

1.1

46.47

26.49

u/l

1.36

339

Neurological diseases

289

971

1.50

8.83

1.2

1.1

24.15

24.06

u/l

0.01

216

745

Weight loss

156

2.78

8.79

1.0

1.1

18.29

27.27

u/l

0.87

110

Concussion

156

798

1.70

8.79

1.1

21.03

22.05

u/l

0.12

111

622

Peripheral arterial reconstruction

269

2.32

8.75

1.2

1.1

47.73

30.78

u/l

0.87

195

Supplementary factors related to causes of morbidity and mortality classified elsewhere

104

550

1.90

8.71

1.2

1.1

27.55

24.05

u/l

0.19

424

Anxiety disorders

299

1449

1.46

8.68

1.2

1.1

34.22

22.99

u/l

1.01

222

1133

Elevated blood glucose level

114

3.09

8.66

1.1

54.09

25.85

u/l

1.00

Other general symptoms and signs

3.99

8.64

1.1

11.69

15.55

u/l

0.47

Implicit fungal Sepsis

4.43

8.63

1.2

1.1

50.33

31.93

u/l

0.25

Extreme obesity with alveolar hypoventilation

3.98

8.62

1.2

1.1

19.84

27.38

u/l

0.35

Psychiatric diseases

383

1360

1.41

8.57

1.2

1.1

32.35

21.75

u/l

1.31

287

1064

Atherosclerosis, excluding cerebral and coronary sclerosis

145

674

1.72

8.57

1.2

1.1

50.39

27.57

u/l

1.64

112

484

Decubitus ulcer and pressure area

3.63

8.56

1.1

104.62

35.27

u/l

1.10

Mood disorders

345

1593

1.42

8.55

1.1

24.40

24.84

u/l

0.03

249

1242

Secondary and unspecified malignant neoplasm of lymph nodes, excluding all cancers (controls excluding all cancers)

229

2.41

8.53

1.1

26.86

22.90

u/l

0.37

165

Other disorders of adrenal gland

3.83

8.52

1.1

1.2

30.11

23.18

u/l

0.31

Mood [affective] disorders

344

1591

1.42

8.51

1.1

24.45

24.84

u/l

0.03

248

1242

Graves disease, strict definition

165

2.68

8.46

1.2

1.1

11.95

21.33

u/l

2.01

131

Missing teeth due to accident, extraction or parodontitis

200

2.52

8.45

1.1

34.45

30.80

u/l

0.16

158

Direct fill therapy

212

2.47

8.43

1.2

1.1

34.04

25.17

u/l

0.45

163

Arthropathies

294

1013

1.48

8.43

1.2

1.1

24.04

22.95

u/l

0.10

230

778

Hypertensive heart and/or renal disease

355

1.99

8.43

1.2

1.1

26.05

24.15

u/l

0.15

259

Certain disorders involving the immune mechanism

352

2.11

8.37

1.1

39.05

24.68

u/l

1.02

267

Isolated proteinuria

4.70

8.37

1.3

1.1

29.74

28.03

u/l

0.04

Candidiasis

225

2.41

8.37

1.2

1.1

37.29

25.28

u/l

0.45

166

Gingivitis and periodontal diseases

307

1085

1.46

8.36

1.1

20.99

26.66

u/l

1.06

220

853

Disorders of continuity of bone

133

2.88

8.31

1.2

1.1

21.95

19.23

u/l

0.18

104

STROKE

202

890

1.58

8.28

1.1

47.59

21.57

u/l

1.80

137

701

Other joint disorders

281

1011

1.48

8.24

1.1

21.68

23.00

u/l

0.16

212

776

Asthma (mode)

248

899

1.52

8.18

1.1

19.60

23.07

u/l

0.57

185

665

Asthma, unspecified (mode)

171

834

1.63

8.18

1.1

18.55

22.74

u/l

0.83

125

619

Type 1 diabetes, definitions combined

102

3.14

8.17

1.2

1.1

21.53

15.90

u/l

0.35

Abnormal findings on diagnostic imaging of other body structures

222

2.40

8.13

1.1

39.75

24.86

u/l

0.46

162

Alcoholic liver disease

146

2.76

8.11

1.1

51.36

33.73

u/l

0.38

109

Bacterial intestinal infections, IBD co-morbidities

317

2.15

8.11

1.1

44.07

28.74

u/l

0.64

237

Myocardial infarction

173

765

1.63

8.11

1.1

49.43

24.33

u/l

1.57

131

572

Type 1 diabetes, strict (exclude DM2)

103

3.11

8.05

1.2

1.1

21.53

15.49

u/l

0.38

Acute bronchitis

134

769

1.71

8.01

1.1

31.58

25.19

u/l

0.67

584

Functional dyspepsia

510

1.89

7.98

1.1

21.78

26.33

u/l

0.49

388

Leisure time condition

281

2.22

7.94

1.1

21.45

25.91

u/l

0.49

216

Asthma

249

888

1.51

7.92

1.1

19.73

22.69

u/l

0.46

186

655

In situ neoplasms

110

582

1.81

7.91

1.1

20.69

21.46

u/l

0.09

431

Abnormal spermatozoa

166

2.61

7.84

1.2

1.1

20.77

41.78

u/l

1.68

128

Haemorrhage from respiratory passages

114

595

1.78

7.80

1.1

28.95

29.13

u/l

0.01

435

Soft tissue disorders

335

1230

1.42

7.75

1.2

1.1

24.82

24.49

u/l

0.03

261

936

Pain (limb, back, neck, head abdominally)

247

824

1.50

7.70

1.1

26.76

25.93

u/l

0.06

186

629

Coronary atherosclerosis

233

1000

1.51

7.68

1.2

1.1

37.50

24.11

u/l

1.54

181

769

Pain, not elsewhere classified

468

1.91

7.65

1.1

23.45

20.77

u/l

0.26

364

Headache

194

1048

1.55

7.64

1.1

25.31

22.12

u/l

0.22

138

806

Sicca syndrome [Sjögren]

151

2.67

7.63

1.1

30.29

23.45

u/l

0.40

108

Acute pancreatitis (for exclusion)

352

2.05

7.62

1.1

59.06

30.24

u/l

0.69

264

Congenital malformations, deformations and chromosomal abnormalities

183

1126

1.56

7.57

1.2

1.1

23.53

24.87

u/l

0.14

140

889

Arthropathic psoriasis

193

2.45

7.56

1.1

29.41

25.37

u/l

0.09

147

Low back pain

244

1275

1.48

7.55

1.1

17.41

25.70

u/l

2.75

188

980

Acute upper respiratory infections

352

1593

1.39

7.47

1.2

1.1

21.36

25.73

u/l

1.08

278

1208

Dental caries 3

279

981

1.46

7.46

1.1

22.83

25.48

u/l

0.29

210

765

Use of hypnotics and sedatives

362

1516

1.38

7.46

1.2

1.1

29.02

24.22

u/l

0.62

263

1177

Conduction disorders

437

1.85

7.38

1.1

31.71

27.87

u/l

0.30

314

Idiopathic gout

120

2.85

7.37

1.0

1.1

34.91

35.65

u/l

0.03

Other abnormal findings of blood chemistry

3.77

7.36

1.1

1.2

20.75

24.59

u/l

0.19

Unspecified jaundice

3.76

7.36

1.0

1.1

75.56

28.63

u/l

0.98

Sensorineural hearing loss

255

1225

1.46

7.35

1.1

23.39

27.68

u/l

0.59

198

914

Depression or dysthymia

243

917

1.49

7.33

1.1

25.46

23.19

u/l

0.23

180

716

Malignant neoplasm of breast, HER-negative

398

1.97

7.33

1.1

15.18

24.24

u/l

1.65

294

Other respiratory disorders and diseases

352

2.03

7.25

1.2

1.1

32.62

30.24

u/l

0.13

259

Other diseases of the respiratory system

352

2.03

7.25

1.2

1.1

32.62

30.24

u/l

0.13

259

Viral pneumonia

167

2.53

7.23

1.2

1.1

32.47

22.81

u/l

0.38

123

Parodontitis or operation codes

303

1589

1.41

7.22

1.2

1.1

20.46

26.40

u/l

1.66

229

1220

Carbimazole or st.post thyroidectomy, condition for graves disease

401

1.95

7.20

1.2

1.1

13.34

21.94

u/l

2.17

307

Alcohol use disorder, Swedish definition

171

1016

1.57

7.18

1.1

43.41

23.59

u/l

1.17

130

766

All influenza (not pneumonia)

210

2.34

7.18

1.2

1.1

35.71

28.79

u/l

0.27

156

Other CVD

320

2.07

7.16

1.2

1.1

39.47

31.22

u/l

0.23

237

Ischaemic heart disease, wide definition

268

1164

1.44

7.16

1.2

1.1

41.34

23.31

u/l

1.86

209

887

Vitamin deficiency

3.57

7.15

1.2

1.1

24.88

22.14

u/l

0.10

Vitamin deficiency, wide

3.57

7.15

1.2

1.1

24.88

22.14

u/l

0.10

Other gastritis (incl. Duodenitis)

402

1.95

7.15

1.1

28.31

29.99

u/l

0.11

294

Cystitis

290

1248

1.42

7.14

1.1

22.05

24.83

u/l

0.48

204

981

Parodontitis

302

1589

1.40

7.10

1.2

1.1

20.54

26.39

u/l

1.62

228

1220

Chronic periodontitis, including avohilmo

301

1589

1.40

7.10

1.2

1.1

20.59

26.39

u/l

1.59

227

1220

Type of accident

502

1.84

7.09

1.2

1.1

28.82

24.05

u/l

0.24

386

Fracture of lumbar spine and pelvis

382

1.97

7.09

1.1

32.28

31.04

u/l

0.07

284

Other and unspecified local infections of skin and subcutaneous tissue

134

2.70

7.08

1.1

42.96

25.66

u/l

0.29

Examination and observation for other reasons

174

671

1.58

7.07

1.2

1.1

29.26

23.42

u/l

0.48

140

526

Open wound of ankle and foot

140

2.66

7.05

1.2

1.1

41.42

25.46

u/l

0.45

109

Asthma (only as main-diagnosis), excluding more controls

211

833

1.51

7.03

1.1

19.83

21.65

u/l

0.20

156

622

Other local infections of skin and subcutaneous tissue

152

2.58

7.01

1.1

41.89

25.78

u/l

0.28

107

Disorders of sclera, cornea, iris and ciliary body

177

1152

1.54

6.99

1.1

21.64

26.75

u/l

0.63

137

889

Myocardial infarction, without ST-elevation

130

723

1.66

6.99

1.2

1.1

50.36

28.80

u/l

1.09

531

Other or unspecified ileus, impaction or obstruction

303

2.09

6.99

1.3

1.1

32.64

27.11

u/l

0.20

210

Intestinal malabsorption

3.41

6.98

1.3

1.1

29.01

26.07

u/l

0.11

Secondary malignant neoplasm of respiratory and digestive organs, excluding all cancers (controls excluding all cancers)

277

2.14

6.98

1.2

1.1

77.57

24.47

u/l

1.99

202

Injuries to the head

353

1684

1.37

6.97

1.1

31.71

23.04

u/l

0.92

253

1305

Polycystic ovarian syndrome, consortium definition

245

1013

1.46

6.95

1.2

1.1

18.40

22.16

u/l

0.73

192

791

Chronic gastritis

527

1.81

6.95

1.1

19.39

29.77

u/l

1.98

385

Other follicular disorders

3.01

6.92

1.1

20.33

26.50

u/l

0.45

Conductive and sensorineural hearing loss

265

1284

1.43

6.92

1.1

22.47

27.08

u/l

0.70

205

962

Internal derangement of knee

127

765

1.66

6.87

1.2

1.1

17.28

25.28

u/l

2.03

103

589

Faecal incontinence

154

2.55

6.84

1.2

13.10

24.81

u/l

2.12

113

186

1098

1.52

6.83

1.1

43.32

23.04

u/l

1.38

142

834

Parodontitis and operation codes

286

1586

1.40

6.83

1.2

1.1

20.06

26.25

u/l

1.72

215

1219

Gonarthrosis

225

872

1.48

6.80

1.1

28.75

25.49

u/l

0.20

174

667

Pyogenic arthritis

2.98

6.80

1.1

1.0

40.33

32.38

u/l

0.14

Diseases of pulp and periapical tissues, including avohilmo

350

1327

1.37

6.78

1.2

1.1

22.11

26.24

u/l

0.70

266

1032

Total colectomy operation

3.53

6.72

1.3

1.1

22.62

29.16

u/l

0.39

Total colectomy

3.53

6.72

1.3

1.1

22.63

29.16

u/l

0.39

Benign neoplasm of colon, rectum, anus and anal canal

206

1258

1.48

6.69

1.1

28.70

27.06

u/l

0.15

171

938

Other disorders of lacrimal gland

122

735

1.67

6.68

1.1

20.80

25.43

u/l

0.54

571

Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly

228

2.22

6.68

1.2

1.1

22.48

25.79

u/l

0.19

174

Hidradenitis suppurativa

3.74

6.65

1.2

1.1

19.88

29.80

u/l

0.57

Injuries to the elbow and forearm

226

1410

1.45

6.63

1.2

1.1

24.04

25.49

u/l

0.16

158

1099

Fentanyl

151

2.53

6.58

1.1

53.44

34.64

u/l

0.59

112

Seronegative rheumatoid arthritis

200

2.31

6.57

1.1

20.34

26.97

u/l

0.61

141

Open wound of head

160

1019

1.55

6.53

1.1

29.09

24.74

u/l

0.51

123

779

Other acute lower respiratory infections

161

994

1.55

6.52

1.1

34.43

25.98

u/l

0.92

119

758

Other diseases of blood and blood-forming organs

101

2.89

6.47

1.2

1.1

46.70

21.19

u/l

0.71

Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

147

2.53

6.43

1.1

39.07

28.31

u/l

0.49

107

L02BX Other hormone antagonists and related agents

3.42

6.42

1.2

1.1

36.76

44.55

u/l

0.22

Benign neoplasm of other and ill-defined parts of digestive system

341

1.97

6.42

1.1

22.20

30.99

u/l

1.04

254

Other CVD (FINNGEN)

132

2.46

6.37

1.2

1.1

44.36

17.93

u/l

0.56

102

Major coronary heart disease event

232

1073

1.44

6.37

1.1

45.95

23.03

u/l

1.84

160

815

Dental pulpitis 1

347

1330

1.36

6.33

1.2

1.1

22.22

26.20

u/l

0.66

263

1035

Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances

255

2.13

6.33

1.2

1.1

18.73

18.71

u/l

0.00

205

Dental pulpitis 4

347

1330

1.36

6.32

1.2

1.1

22.22

26.20

u/l

0.66

263

1035

Disorders of synovium and tendon

176

1053

1.51

6.28

1.1

32.31

25.16

u/l

0.51

133

802

Other respiratory diseases principally affecting the interstitium

296

2.04

6.27

1.2

1.1

31.96

33.56

u/l

0.06

214

Myocardial infarction, strict

154

720

1.56

6.27

1.2

1.1

45.83

25.26

u/l

1.18

119

536

Symptoms and signs involving the nervous and musculoskeletal systems

186

1254

1.49

6.26

1.1

29.85

24.13

u/l

0.23

103

1003

Other problems related to primary support group, including family circumstances

151

2.46

6.23

1.2

1.1

11.10

18.22

u/l

1.53

122

Other abnormal uterine and vaginal bleeding

357

1.80

6.21

1.2

1.1

22.49

26.81

u/l

0.38

268

Pruritus

168

2.39

6.19

1.3

1.1

21.16

25.95

u/l

0.37

124

Ankylosing spondylitis, ICD10

138

2.55

6.19

1.1

13.20

22.42

u/l

1.46

100

Developmental endpoint to exclude non autoimmune-cases from E4_HYTHY_AI_STRICT

113

682

1.66

6.18

1.1

31.16

23.95

u/l

0.22

532

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperum or nerve system disorders, excluding more controls

452

1.82

6.17

1.2

1.1

18.12

20.84

u/l

0.40

366

Coxarthrosis [arthrosis of hip](FG)

171

815

1.52

6.14

1.1

24.08

23.75

u/l

0.03

130

613

Other infective otitis externa

2.85

6.10

1.3

1.1

20.74

26.04

u/l

0.38

Other diseases of intestine

188

2.30

6.09

1.1

27.86

27.49

u/l

0.02

131

Diseases of the musculoskeletal system and connective tissue

158

506

1.57

6.07

1.2

1.1

19.57

22.63

u/l

0.37

125

381

Other arrhythmias

204

1073

1.46

6.04

1.1

21.58

22.29

u/l

0.10

163

819

Impacted cerumen

152

2.45

6.02

1.1

17.12

31.75

u/l

1.58

107

COPD (mode)

445

1.73

6.00

1.2

1.1

22.85

24.36

u/l

0.13

305

Substance abuse, excluding more controls

169

984

1.51

5.98

1.1

45.62

21.04

u/l

1.56

127

772

Alcohol-induced chronic pancreatitis

3.00

5.95

1.1

60.26

27.99

u/l

0.62

Methotrexate

249

2.10

5.91

1.2

1.1

30.66

24.83

u/l

0.19

178

Diverticular disease of intestine

233

1090

1.42

5.90

1.2

1.1

22.68

25.41

u/l

0.35

193

804

Factors influencing health status and contact with health services

249

1.82

5.90

1.1

27.50

22.26

u/l

0.38

196

Asthma (only as main-diagnosis)

213

888

1.45

5.87

1.1

19.92

22.69

u/l

0.32

158

655

Polyp of the female genital tract

122

433

1.64

5.85

1.2

1.1

23.25

23.77

u/l

0.03

332

Dental operations

211

743

1.46

5.84

1.1

27.19

27.38

u/l

0.01

159

579

Bronchitis

338

1662

1.34

5.83

1.2

1.1

26.23

24.40

u/l

0.26

257

1273

Lower back pain or/and sciatica

326

1690

1.34

5.81

1.1

18.84

26.02

u/l

2.04

250

1296

Benign neoplasm: Colon, unspecified

387

1.86

5.81

1.2

1.1

33.40

22.42

u/l

1.15

279

Pacemaker

104

607

1.67

5.80

1.1

32.36

32.02

u/l

0.02

441

Other skin changes

312

1.96

5.80

1.2

1.1

40.36

27.69

u/l

0.60

228

Chronic lower respiratory diseases

389

1604

1.31

5.78

1.1

22.02

25.45

u/l

0.57

296

1238

Acute upper respiratory infections of multiple and unspecified sites

229

1214

1.42

5.78

1.2

1.1

22.30

24.86

u/l

0.38

181

927

Non-Hodgkin lymphoma, all, excluding all cancers (controls excluding all cancers)

200

2.21

5.71

1.1

47.76

24.66

u/l

0.90

144

Substance use, excluding alcohol

307

1.96

5.70

1.2

1.1

23.05

23.84

u/l

0.04

238

Secondary and unspecified malignant neoplasm of lymph nodes

132

2.52

5.69

1.1

34.99

31.31

u/l

0.21

Other diseases of oesophagus

132

2.51

5.68

1.1

1.2

65.66

37.77

u/l

0.23

Pleural effusion

253

2.06

5.68

1.1

48.87

33.64

u/l

0.68

183

Disorders of lacrimal system

143

934

1.53

5.67

1.1

20.73

25.80

u/l

0.74

114

728

Benign neoplasm: Colon

169

1120

1.48

5.64

1.2

1.1

30.42

25.13

u/l

0.55

143

829

171

1063

1.48

5.63

1.1

44.88

23.04

u/l

1.40

133

801

Other disorders of conjunctiva

254

2.06

5.63

1.1

14.04

28.70

u/l

2.81

185

Mental and behavioural disorders due to psychoactive substance use

178

1148

1.47

5.61

1.1

44.80

23.00

u/l

1.41

135

871

Paracetamol of NSAID medication

117

2.20

5.60

1.1

26.22

18.50

u/l

0.52

Benign neoplasms

300

1237

1.36

5.58

1.2

1.1

30.78

23.88

u/l

0.65

235

934

Retention of urine

499

1.68

5.57

1.1

41.91

28.29

u/l

0.56

374

Disorders of eyelid, lacrimal system and orbit

276

1593

1.36

5.57

1.1

23.87

25.27

u/l

0.15

206

1225

Keratitis

110

679

1.62

5.56

1.1

20.20

28.14

u/l

1.21

523

Primary gonarthrosis, bilateral

175

1045

1.47

5.52

1.1

28.43

26.60

u/l

0.18

135

797

Injuries to the ankle and foot

205

1314

1.42

5.51

1.2

1.1

22.57

24.01

u/l

0.14

151

1033

Dental caries 3, only avohilmo

275

1025

1.37

5.47

1.1

24.11

25.73

u/l

0.15

206

799

Abnormal findings on examination of urine, without diagnosis

3.25

5.45

1.3

1.1

29.74

27.44

u/l

0.06

Gonarthrosis,primary

300

1404

1.35

5.45

1.2

1.1

28.40

24.68

u/l

0.31

226

1074

Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)

123

607

1.58

5.41

1.1

38.74

21.83

u/l

1.74

446

Dental caries, including avohilmo

251

923

1.39

5.41

1.1

24.28

25.58

u/l

0.12

189

725

Dental caries 1

251

923

1.39

5.40

1.1

24.28

25.58

u/l

0.12

189

725

Hypopituitarism

2.82

5.40

1.2

1.1

89.06

22.76

u/l

0.53

Ankylosing spondylitis

154

2.35

5.39

1.1

12.91

27.32

u/l

2.33

119

Degeneration of macula and posterior pole

147

801

1.52

5.39

1.2

1.1

28.50

26.58

u/l

0.19

115

587

Poisoning by medicine

356

1.86

5.38

1.2

1.1

19.76

18.31

u/l

0.13

283

Respiratory insufficiency

106

2.65

5.38

1.1

23.76

29.50

u/l

0.23

Pulmonary heart disease, diseases of pulmonary circulation

101

616

1.64

5.36

1.1

37.21

27.39

u/l

0.79

457

ILD, hospital admission 2, with pulmonary infections

130

2.47

5.36

1.1

26.12

34.85

u/l

0.41

Volume depletion

130

2.47

5.36

1.3

1.1

15.15

28.91

u/l

1.52

Intracranial injury

170

1125

1.46

5.34

1.1

25.62

24.44

u/l

0.09

121

854

Spondylopathies

268

1193

1.37

5.34

1.2

1.1

28.72

26.23

u/l

0.16

206

916

Hypoglycaemia, other or unspecified

101

2.69

5.33

1.3

1.1

29.20

22.84

u/l

0.30

Neovascular glaucoma

3.30

5.31

1.2

1.1

43.50

22.78

u/l

0.69

Abnormal weight loss

143

2.39

5.30

1.0

1.1

20.38

28.45

u/l

0.64

Polyarthrosis

391

1.80

5.29

1.2

1.1

26.77

24.83

u/l

0.13

304

ILD, hospital admissions 3, with pneumonia sepsis

113

2.58

5.29

1.1

28.19

33.73

u/l

0.20

Injuries to the abdomen, lower back, lumbar spine and pelvis

117

739

1.58

5.24

1.1

30.06

26.28

u/l

0.32

562

Early onset COPD, excluding more controls

352

1.85

5.24

1.2

1.1

23.54

25.46

u/l

0.14

248

Other pleural conditions

150

2.34

5.23

1.1

31.93

32.16

u/l

0.01

107

Other otitis externa (chronic)

108

2.61

5.22

1.1

14.61

27.96

u/l

1.30

Stroke, including SAH

199

1037

1.42

5.21

1.1

48.88

23.49

u/l

1.67

133

792

Other and unspecified disorders of white blood cells

3.15

5.20

1.1

1.2

62.43

23.52

u/l

1.25

Colectomy operation

297

1.93

5.18

1.2

1.1

35.20

31.97

u/l

0.10

222

ILD, hospital admissions

242

2.03

5.18

1.2

1.1

33.43

35.70

u/l

0.08

174

Mixed hyperlipidaemia

3.25

5.18

1.2

1.1

32.51

26.84

u/l

0.19

Glaucoma secondary to other eye disorders

3.25

5.18

1.2

1.1

43.50

25.83

u/l

0.56

Coeliac disease

189

2.18

5.17

1.2

1.1

45.45

22.33

u/l

0.48

147

Non-selective monoamine reuptake inhibitors

134

855

1.52

5.16

1.1

21.17

29.81

u/l

0.98

668

Gonarthrosis, primary, with knee surgery

190

1089

1.43

5.15

1.1

27.86

26.27

u/l

0.16

144

827

Special screening examination for other diseases and disorders

103

2.63

5.14

1.3

1.1

15.57

28.28

u/l

0.82

ILD, hospital admissions 1, main diag only

216

2.09

5.13

1.2

1.1

35.24

36.42

u/l

0.03

158

Other noninflammatory disorders of vulva and perineum

139

2.39

5.13

1.3

1.2

25.36

20.22

u/l

0.32

110

Infections with a predominantly sexual mode of transmission

524

1.68

5.13

1.2

1.1

38.94

17.02

u/l

1.30

413

Stroke, excluding SAH

187

971

1.43

5.11

1.1

49.62

24.26

u/l

1.56

127

734

Contact with and exposure to communicable diseases

486

1.70

5.08

1.2

1.1

23.77

16.94

u/l

0.42

384

Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified

311

1534

1.32

5.07

1.2

1.1

23.68

25.49

u/l

0.27

232

1188

Orthopaedic devices associated with adverse incidents

4.52

5.06

1.4

1.1

36.83

31.95

u/l

0.15

Substance abuse

169

1118

1.45

5.05

1.1

45.62

23.51

u/l

1.32

127

848

Other interstitial pulmonary diseases

245

2.01

5.02

1.2

1.1

33.43

35.64

u/l

0.07

176

Osteonecrosis

2.82

4.98

1.1

32.69

21.42

u/l

0.39

Suicide or other Intentional self-harm

439

1.74

4.98

1.2

1.1

18.61

21.87

u/l

0.44

341

Interstitial lung disease endpoints

246

2.00

4.97

1.2

1.1

33.42

35.48

u/l

0.07

177

Interstitial lung disease

246

2.00

4.97

1.2

1.1

33.42

35.48

u/l

0.07

177

Mixed connective tissue disease

111

2.54

4.96

1.1

32.24

23.10

u/l

0.45

Infective dermatitis

173

2.21

4.96

1.1

64.44

29.19

u/l

0.60

132

severe traumatic brain injury, does not include concussion

359

1.82

4.95

1.1

37.20

30.95

u/l

0.22

269

Secondary uncertain malignant neoplasm

213

2.07

4.92

1.2

1.1

57.46

29.63

u/l

1.23

158

Other and unspecified nail disorders

4.12

4.91

1.0

1.2

17.88

31.12

u/l

—

Exclusions for E4_PCOS_CONSORTIUM

234

1069

1.37

4.90

1.2

1.1

28.91

21.62

u/l

0.55

183

830

Hypoparathyroidism

3.36

4.89

1.2

1.1

175.73

23.44

u/l

0.74

Acute suppurative otitis media

322

1.83

4.88

1.2

1.1

21.38

16.35

u/l

0.61

251

Disorders of skin appendages

143

967

1.48

4.85

1.1

27.07

25.31

u/l

0.09

115

758

External causes of morbidity and mortality

218

783

1.40

4.83

1.2

1.1

27.22

21.54

u/l

0.69

170

596

Otitis externa

384

1.78

4.83

1.2

1.1

20.79

24.06

u/l

0.25

294

Dental pulpitis 2, only avohilmo

228

844

1.38

4.82

1.1

25.41

25.84

u/l

0.03

171

666

Urticaria and erythema

114

737

1.55

4.80

1.2

1.1

26.65

23.05

u/l

0.30

573

Other external causes of accidental injury

273

1018

1.34

4.80

1.1

27.38

22.96

u/l

0.43

202

782

Dental pulpitis 2

221

815

1.39

4.79

1.1

25.68

25.75

u/l

0.01

165

638

Aortic valve malfunction, age under 60 years

150

2.28

4.79

1.2

1.1

61.03

22.96

u/l

0.52

114

Disorders of conjunctiva

249

1553

1.34

4.76

1.2

1.1

21.91

25.25

u/l

0.40

201

1193

Cerebrovascular diseases

233

1228

1.36

4.73

1.1

44.84

24.33

u/l

1.58

162

942

Viral and other specified intestinal infections

258

1.93

4.72

1.2

1.1

23.69

15.94

u/l

0.35

196

Superficial injury of hip and thigh

224

2.02

4.68

1.3

1.1

29.28

24.41

u/l

0.28

171

Acute sinusitis

154

992

1.45

4.67

1.1

20.39

25.94

u/l

0.86

121

770

Temporomandibular joint disorders

287

1.89

4.66

1.1

32.84

23.07

u/l

0.42

229

Hypotension

252

1.95

4.66

1.2

1.1

47.93

33.68

u/l

0.27

183

Tubulo-interstitial nephritis, not specified as acute or chronic

2.65

4.65

1.3

1.1

18.42

28.36

u/l

0.67

Diseases of salivary glands

345

1.80

4.64

1.1

33.94

27.03

u/l

0.20

273

Fracture of forearm

175

1161

1.41

4.64

1.1

24.53

25.36

u/l

0.08

124

906

Postprocedural musculoskeletal disorders, not elsewhere classified

115

2.45

4.63

1.2

1.1

23.52

25.35

u/l

0.06

Acute myeloid leukaemia and myelodysplastic syndromes, excluding all cancers (controls excluding all cancers)

3.52

4.62

1.1

69.86

21.21

u/l

—

Traumatic subdural haemorrhage

189

2.09

4.57

1.1

44.58

23.88

u/l

0.61

139

Other diseases of lip and oral mucosa

275

1.90

4.57

1.2

1.1

25.56

28.04

u/l

0.16

215

Persons with potential health hazards related to communicable diseases

102

646

1.57

4.55

1.2

1.1

23.81

20.20

u/l

0.23

503

Anxiety (asthma-related co-morbidities)

172

958

1.42

4.53

1.2

33.85

20.05

u/l

0.80

131

762

Arthrosis

227

915

1.37

4.51

1.1

29.52

24.69

u/l

0.31

174

704

Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)

129

2.34

4.50

1.2

1.1

62.67

16.74

u/l

0.43

Major coronary heart disease event excluding revascularizations

199

994

1.38

4.47

1.1

47.01

23.37

u/l

1.75

150

751

Other (seronegative) rheumatoid arthritis, wide

379

1.75

4.46

1.1

22.74

27.60

u/l

0.57

282

Rheumatism, unspecified

299

1.85

4.45

1.1

17.00

19.79

u/l

0.29

225

Symptoms and signs involving the skin and subcutaneous tissue

213

1566

1.36

4.43

1.2

1.1

26.43

24.77

u/l

0.17

171

1193

Injuries to the thorax

129

873

1.48

4.41

1.2

1.1

23.28

27.90

u/l

0.33

661

Poisoning by drugs, medicaments and biological substances

395

1.73

4.41

1.2

1.1

20.17

19.86

u/l

0.03

311

Polymyalgia rheumatica

209

2.02

4.40

1.1

54.87

28.07

u/l

0.50

149

Dorsalgia

311

1298

1.30

4.40

1.1

20.03

25.44

u/l

1.12

238

994

Atopic dermatitis, strict definition with reimbursement

478

1.65

4.40

1.2

1.1

14.60

18.66

u/l

0.57

368

Other and unspecified psoriasis

106

2.47

4.38

1.2

1.1

23.86

23.50

u/l

0.02

Ischaemic Stroke, excluding all haemorrhages

172

924

1.41

4.37

1.1

45.56

24.39

u/l

1.22

120

697

Biguanides

304

1446

1.30

4.36

1.1

27.63

24.97

u/l

0.27

235

1108

Injuries to the knee and lower leg

367

1658

1.27

4.36

1.1

25.26

24.27

u/l

0.10

295

1256

Personality disorders, excluding more controls

397

1.72

4.34

1.2

1.1

44.67

20.08

u/l

0.49

324

Other metabolic disorders

231

1.96

4.33

1.1

57.47

18.89

u/l

0.46

177

Viral warts

144

2.23

4.33

1.3

1.1

25.77

22.61

u/l

0.16

108

Congenital iodine-deficiency syndrome/hypothyroidism

3.36

4.33

1.1

130.28

28.67

u/l

—

Postprocedural endocrine and metabolic disorders, not elsewhere classified

211

2.00

4.30

1.1

63.36

18.67

u/l

0.47

166

Invasive ventilation

107

2.44

4.30

1.2

1.1

75.57

32.58

u/l

0.77

Moderate visual impairment, binocular

3.90

4.26

1.4

1.1

25.00

33.28

u/l

0.23

Trigger finger

283

1.84

4.22

1.3

1.1

42.89

24.91

u/l

0.53

216

Malignant neoplasm of skin, excluding all cancers (controls excluding all cancers)

151

719

1.44

4.21

1.2

1.1

28.93

22.37

u/l

0.77

119

531

Hypertensive Heart Disease

331

1.71

4.21

1.2

1.1

27.39

24.26

u/l

0.23

239

Left ventricular outflow tract obstruction (LVOTO), broad definition

159

2.15

4.20

1.2

1.1

61.03

22.42

u/l

0.53

121

Pulmonary embolism

562

1.59

4.20

1.2

1.1

38.05

27.61

u/l

0.75

414

Myalgia

424

1.68

4.19

1.1

28.86

22.88

u/l

0.31

332

Other diseases of upper respiratory tract

356

1465

1.27

4.18

1.1

20.70

26.50

u/l

0.73

279

1108

Seborrhoeic dermatitis

140

2.22

4.17

1.3

1.1

45.05

33.31

u/l

0.17

100

Hernia of abdominal wall

133

917

1.45

4.17

1.2

1.1

31.96

27.57

u/l

0.23

109

686

Fall on same level involving ice and snow

170

1227

1.39

4.13

1.1

27.26

25.61

u/l

0.09

117

966

Other other unspecified disorders of the circulatory system

3.01

4.13

1.1

1.2

24.53

23.27

u/l

0.06

Coxarthrosis

157

751

1.42

4.12

1.1

24.82

24.64

u/l

0.01

119

568

Suppurative and unspecified otitis media

499

1.58

4.11

1.2

1.1

29.10

23.22

u/l

0.28

379

Follow-up examination after treatment for malignant neoplasms

174

2.08

4.10

1.1

16.99

25.09

u/l

0.87

136

L02BB Anti-androgens

122

2.31

4.10

1.3

1.1

45.00

43.00

u/l

0.04

Superficial injury of lower leg

435

1.66

4.08

1.1

33.42

24.02

u/l

0.38

328

Pulmonary heart disease

567

1.57

4.06

1.2

1.1

38.05

27.63

u/l

0.75

418

Traumatic subarachnoid haemorrhage

3.54

4.05

1.2

1.0

85.84

28.79

u/l

—

Coronary revascularization (ANGIO or CABG)

141

683

1.44

4.05

1.2

1.1

40.29

25.43

u/l

0.92

506

Acute and subacute iridocyclitis

346

1.74

4.03

1.2

1.1

21.35

25.89

u/l

0.20

263

Dental operations, only avohilmo

218

829

1.35

4.00

1.1

28.37

27.09

u/l

0.09

161

649

All anxiety disorders

173

1010

1.38

3.98

1.2

1.1

33.61

20.00

u/l

0.79

132

794

Fracture of rib(s), sternum and thoracic spine

532

1.58

3.95

1.1

23.63

28.86

u/l

0.27

413

Presbycusis

203

1.97

3.95

1.1

21.98

37.70

u/l

1.31

135

Abnormalities of heart beat

103

677

1.51

3.94

1.1

24.49

25.57

u/l

0.08

511

Dental caries 1, only avohilmo

249

967

1.32

3.93

1.1

24.00

25.82

u/l

0.17

187

759

Persons with potential health hazards related to socioeconomic and psychosocial circumstances

442

1.64

3.93

1.1

18.46

18.86

u/l

0.03

350

Myelodysplastic syndrome, excluding all cancers (controls excluding all cancers)

3.67

3.93

1.1

79.83

26.99

u/l

—

Superficial injury of ankle and foot

157

2.11

3.93

1.2

1.1

28.69

18.67

u/l

0.50

123

Selective serotonin reuptake inhibitors

311

1283

1.28

3.91

1.1

21.45

26.56

u/l

0.88

235

990

Dental pulpitis 4, only avohilmo

339

1402

1.26

3.89

1.1

20.47

26.49

u/l

1.44

257

1096

178

2.03

3.88

1.3

1.1

73.57

22.58

u/l

0.71

148

Nail disorders

132

2.21

3.86

1.1

59.57

21.81

u/l

0.68

Benign paroxysmal vertigo

600

1.54

3.82

1.1

22.88

27.15

u/l

0.31

454

Any mental disorder, or suicide (or attempt), or psychic disorders complicating pregnancy, partum or puerperium or nerve system disorders

521

1.58

3.82

1.2

1.1

18.12

20.78

u/l

0.39

412

Haemorrhage, not elsewhere classified

3.20

3.78

1.4

1.2

30.11

31.59

u/l

—

In situ neoplasms

110

747

1.48

3.77

1.1

20.69

25.48

u/l

0.76

562

Inflammatory diseases of female pelvic organs

193

1083

1.34

3.75

1.2

1.1

21.28

u/l

0.00

158

840

Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)

147

2.12

3.74

1.1

80.52

26.08

u/l

0.66

105

Type 1 diabetes, strict definition, subgroup 1

2.73

3.73

1.1

1.0

21.41

14.80

u/l

0.25

Other extrapyramidal and movement disorders in other diseases

423

1.64

3.73

1.1

17.96

30.37

u/l

1.88

320

Speech disturbances, not elsewhere classified

134

2.17

3.73

1.1

24.74

29.48

u/l

0.25

Other neurological diseases

218

1332

1.32

3.72

1.1

33.77

24.85

u/l

0.58

152

1023

Fracture of foot, except ankle

431

1.63

3.72

1.3

1.1

20.29

20.37

u/l

0.01

331

Autoimmune hyperthyroidism

2.58

3.71

1.2

1.1

10.12

25.62

u/l

2.16

Other hearing loss

500

1.58

3.71

1.2

1.1

30.17

32.47

u/l

0.11

360

Duodenal ulcer

161

2.06

3.70

1.1

25.12

42.06

u/l

0.84

113

Presence of other devices

401

1.65

3.69

1.1

19.28

32.18

u/l

1.93

287

Other sleep disorders

168

2.03

3.69

1.1

13.99

23.35

u/l

1.08

132

Iridocyclitis

417

1.63

3.68

1.1

21.63

25.13

u/l

0.17

314

Colorectal cancer, excluding all cancers (controls excluding all cancers)

449

1.60

3.63

1.1

33.08

23.27

u/l

0.75

330

Accidents

262

1018

1.29

3.57

1.1

27.76

22.96

u/l

0.46

194

782

Dysphagia

421

1.62

3.55

1.1

25.91

27.35

u/l

0.07

317

Calcific aortic valvular stenosis, diagnosis (helper)

527

1.54

3.55

1.1

42.83

32.39

u/l

0.28

385

Operations 2 for CAVS

527

1.54

3.55

1.1

42.83

32.39

u/l

0.28

385

Other/unspecified rheumatoid arthritis

234

1.84

3.54

1.0

1.1

24.89

29.89

u/l

0.41

172

Myocardial infarction, unclassifiable

333

1.66

3.54

1.1

69.80

29.43

u/l

1.11

242

Dislocation, sprain and strain of joint and ligaments of hip

3.07

3.53

1.2

1.1

38.29

22.72

u/l

0.24

Atopic dermatitis

149

921

1.38

3.53

1.2

1.1

14.42

23.23

u/l

2.51

124

720

Calcific aortic valvular stenosis

528

1.54

3.52

1.1

42.83

32.32

u/l

0.28

386

Calcific aortic valvular stenosis, operated

528

1.54

3.52

1.1

42.83

32.32

u/l

0.28

386

Pain associated with micturition

185

1.95

3.52

1.3

1.1

11.67

27.41

u/l

3.55

139

Seropositive rheumatoid arthritis, strict definition

286

1.75

3.51

1.2

1.1

20.35

23.90

u/l

0.39

217

Malignant neoplasm of bladder, excluding all cancers (controls excluding all cancers)

171

1.99

3.50

1.1

16.47

26.58

u/l

1.19

123

Unspecific neurodegenerative disorder

604

0.59

3.50

1.0

1.1

36.70

30.80

u/l

0.23

431

Other and unspecified urticaria

339

1.69

3.48

1.2

1.1

28.46

19.96

u/l

0.57

256

Calcific aortic valvular stenosis, including rheumatic fever

529

1.54

3.48

1.1

42.83

32.43

u/l

0.28

386

Car occupant injured in other and unspecified transport accidents

294

1.74

3.48

1.1

23.21

22.80

u/l

0.02

232

Dermatophytosis

214

1.88

3.48

1.1

29.78

29.97

u/l

0.01

160

Open wound of wrist and hand

113

777

1.44

3.48

1.2

1.1

28.61

27.52

u/l

0.05

596

Shoulder lesions

237

1121

1.30

3.47

1.2

1.1

22.26

25.90

u/l

0.49

188

853

Amenorrhoea

2.54

3.46

1.2

17.06

17.25

u/l

0.01

Degenerative macular diseases

215

1.87

3.44

1.2

1.1

29.97

33.24

u/l

0.12

151

Benign neoplasm: Rectum, anus and anal canal

318

1.70

3.43

1.2

1.1

19.30

24.32

u/l

0.62

231

Follicular lymphoma

2.78

3.42

1.1

30.36

18.79

u/l

0.49

Malignant melanoma, excluding all cancers (controls excluding all cancers)

281

1.75

3.41

1.2

1.1

26.97

23.51

u/l

0.19

201

Open wound of forearm

126

2.15

3.41

1.2

1.1

25.59

28.57

u/l

0.14

Diagnoses used for exclusion with ILD

482

1.56

3.37

1.1

31.66

27.36

u/l

0.35

363

Primary coxarthrosis, bilateral

586

1.51

3.37

1.1

24.65

27.45

u/l

0.18

435

Somatoform disorder

290

1.73

3.36

1.1

28.05

20.43

u/l

0.25

225

Dental pulpitis 1, only avohilmo

335

1411

1.24

3.35

1.1

20.53

26.39

u/l

1.38

255

1103

Anterior Iridocyclitis

374

1.64

3.34

1.1

22.10

25.72

u/l

0.15

283

Sequelae of cerebrovascular disease

100

599

1.47

3.33

1.1

41.77

27.92

u/l

0.73

453

Benign neoplasm of other and unspecified endocrine glands

196

1.89

3.33

1.2

1.1

31.69

20.97

u/l

0.32

143

Injuries to the wrist and hand

290

1680

1.25

3.33

1.1

27.24

23.98

u/l

0.30

221

1291

Cerebral palsy and other paralytic syndromes

175

1.95

3.32

1.2

1.1

23.63

26.29

u/l

0.08

132

Symptoms and signs involving cognition, perception, emotional state and behaviour

293

1643

1.25

3.32

1.1

30.18

24.24

u/l

0.65

207

1277

Malignant neoplasm of colon, excluding all cancers (controls excluding all cancers)

306

1.70

3.32

1.1

33.67

24.84

u/l

0.45

220

Diseases of inner ear

164

1198

1.34

3.31

1.1

21.59

26.87

u/l

0.68

130

914

Coronary angioplasty

111

592

1.44

3.31

1.1

41.66

26.97

u/l

0.63

440

Open wound of lower leg

218

1.84

3.30

1.1

74.68

27.70

u/l

0.89

165

Pleural plaque

148

2.04

3.30

1.1

40.30

39.43

u/l

0.02

108

Dental pulpitis 3, only avohilmo

2.37

3.26

1.2

1.1

9.75

7.67

u/l

0.43

Viral pneumonia (unknown virus, not influenza)

2.34

3.24

1.2

1.1

14.92

20.98

u/l

0.53

Dentofacial anomalies [including malocclusion]

505

1.53

3.24

1.2

1.1

31.28

23.15

u/l

0.49

408

L01XX Other antineoplastic agents

2.39

3.23

1.1

53.69

28.55

u/l

1.05

Disorders of vestibular function (Vertigo)

141

1026

1.37

3.23

1.1

22.73

26.49

u/l

0.37

111

785

Venous thromboembolism

160

1160

1.34

3.22

1.2

1.1

31.00

26.15

u/l

0.49

124

879

487

1.51

3.22

1.2

1.1

30.72

32.09

u/l

0.08

347

Other viral diseases, not elsewhere classified

278

1.73

3.22

1.1

28.39

22.51

u/l

0.40

217

Type 1 diabetes, strict definition

2.44

3.19

1.1

21.41

14.88

u/l

0.25

Fibromyalgia

157

1.98

3.19

1.3

1.1

15.89

18.58

u/l

0.25

125

Secondary right heart disease

2.74

3.16

1.1

28.33

25.57

u/l

—

Basal cell carcinoma, excluding all cancers (controls excluding all cancers)

127

628

1.40

3.15

1.2

1.1

28.15

21.56

u/l

0.67

100

464

Leiomyoma of uterus

134

543

1.39

3.15

1.1

21.51

18.59

u/l

0.26

108

402

Emergency coronary revascularization (for ACS)

155

826

1.35

3.14

1.1

39.52

29.49

u/l

0.59

619

Attention to artificial openings

2.97

3.14

1.0

1.1

100.50

21.79

u/l

—

Disorder of lipoprotein metabolism, unspecified

222

1.81

3.14

1.1

35.23

32.56

u/l

0.09

166

Menorrhagia

116

450

1.43

3.13

1.2

1.1

15.88

23.30

u/l

1.55

346

Benign neoplasm: Sigmoid colon

290

1.69

3.09

1.3

1.1

28.04

24.85

u/l

0.11

212

Sodium-glucose co-transporter 2 (SGLT2) inhibitors

477

1.53

3.08

1.1

23.31

27.04

u/l

0.31

372

Sarcoidosis

238

1.77

3.08

1.1

30.32

24.35

u/l

0.41

179

Other disorders of optic [2nd] nerve and visual pathways

2.34

3.08

1.2

1.1

37.57

24.71

u/l

0.24

Fissure and fistula of anal and rectal regions

430

1.56

3.07

1.1

18.16

24.45

u/l

0.79

319

Mental and behavioural disorders due to alcohol

136

973

1.36

3.06

1.1

49.99

23.00

u/l

1.35

104

737

Other and unspecified disorders of vitreous body

129

937

1.37

3.04

1.1

24.12

26.94

u/l

0.22

101

716

Malignant neoplasm of thyroid gland, excluding all cancers (controls excluding all cancers)

119

2.11

3.04

1.2

1.1

13.56

14.87

u/l

0.13

Artificial joint operation, meniscal resection

281

1505

1.24

3.04

1.1

22.49

26.94

u/l

0.82

217

1142

Superficial injury of thorax

232

1.77

3.03

1.2

1.1

16.26

27.95

u/l

1.21

176

Bronchiectasis

126

2.07

3.02

1.2

1.1

31.29

26.44

u/l

0.14

Benign neoplasm: Colon, unspecified

472

1.53

3.01

1.2

1.1

33.40

30.17

u/l

0.21

352

Excessive attrition of teeth

118

454

1.41

3.01

1.1

19.01

26.36

u/l

0.83

355

Female genital prolapse

103

412

1.45

3.00

1.1

17.91

24.68

u/l

0.89

312

Other disorders of cornea

154

1.96

2.99

1.1

14.59

22.12

u/l

0.96

112

Postmenopausal bleeding

102

388

1.45

2.97

1.2

1.1

19.61

25.52

u/l

0.81

293

Vaginitis/vulvovaginitis/vulvitis/abscess of vulva

286

1.68

2.97

1.2

20.04

17.28

u/l

0.27

225

Alcohol abuse, main dg, excluding more controls

197

1.83

2.97

1.1

34.83

26.07

u/l

0.41

154

Herpesviral [herpes simplex] infections

176

1.88

2.94

1.1

35.04

22.68

u/l

0.69

133

Alzheimer disease

419

0.54

2.94

1.1

60.28

31.20

u/l

0.76

296

Adjustment and management of implanted device

287

1.68

2.93

1.0

1.1

29.31

28.30

u/l

0.05

204

Malignant neoplasm of endocrine gland

128

2.04

2.91

1.2

1.1

68.47

24.27

u/l

0.36

Ventral hernia

476

1.52

2.91

1.2

1.1

31.42

26.38

u/l

0.22

351

Haemorrhoids and perianal venous thrombosis

573

1.47

2.90

1.2

1.1

29.12

26.78

u/l

0.15

418

Obesity, other/unspecified

656

1.44

2.90

1.1

17.63

23.65

u/l

1.10

511

Fracture of lower leg, including ankle

161

1221

1.31

2.89

1.1

30.97

26.70

u/l

0.23

126

934

Hypertrophy of breast

366

1.59

2.88

1.1

11.82

20.13

u/l

2.42

285

DVT of lower extremities and pulmonary embolism

120

872

1.37

2.88

1.2

1.1

33.16

27.10

u/l

0.51

653

Trigeminal neuralgia

2.26

2.87

1.3

1.1

14.12

22.04

u/l

0.77

Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)

171

1.88

2.85

1.1

77.66

25.87

u/l

0.65

123

Striking against or struck by other objects

543

1.47

2.84

1.2

1.1

38.31

25.34

u/l

0.56

424

Parodontitis or/and operation codes

204

947

1.28

2.83

1.1

18.90

25.27

u/l

1.27

150

718

Basal cell carcinoma, including avohilmo, excluding all cancers (controls excluding all cancers)

126

634

1.37

2.82

1.2

1.1

28.63

21.69

u/l

0.71

466

Other congenital malformations

116

2.07

2.81

1.1

37.66

21.44

u/l

0.52

Hypertrophy of breast in women and men

408

1.55

2.80

1.1

11.99

21.63

u/l

3.08

316

Dental pulpitis 3

2.15

2.79

1.2

1.1

9.75

11.28

u/l

0.17

Phobic anxiety disorders

158

1.90

2.79

1.3

1.1

32.37

17.57

u/l

0.46

132

Chronic hepatitis NAS

3.97

2.78

1.1

50.33

40.72

u/l

—

Specific personality disorders

393

1.56

2.78

1.2

1.1

47.13

18.94

u/l

0.48

313

Hyperplasia of prostate

362

1.45

2.77

1.1

19.39

36.30

u/l

2.16

269

Flat foot [pes planus] (acquired)

173

1.86

2.76

1.2

1.1

17.88

21.31

u/l

0.27

132

Pre-eclampsia

410

1.54

2.75

1.1

1.2

23.59

19.47

u/l

0.27

328

Drugs, medicaments and biological substances causing adverse effects in therapeutic use

131

1.99

2.75

1.2

1.1

10.50

27.97

u/l

2.79

Urticaria

564

1.46

2.75

1.2

1.1

30.09

22.35

u/l

0.59

435

Sequelae of injuries of head

2.32

2.74

1.3

1.1

44.38

26.28

u/l

0.22

Undetermined asthma, excluding more controls

195

1.80

2.74

1.1

14.37

25.50

u/l

1.24

143

Covid-19 confirmed case

499

1.49

2.74

1.2

1.1

25.16

26.12

u/l

0.05

385

Other dorsopathies, not elsewhere classified

301

1299

1.22

2.73

1.2

1.1

21.50

25.42

u/l

0.68

235

995

Ovarian cyst

113

470

1.39

2.73

1.2

1.1

18.75

22.24

u/l

0.43

363

Degenerative diseases of the nervous system

494

0.59

2.72

1.1

49.27

32.22

u/l

0.59

357

Irregular menses

140

853

1.33

2.72

1.2

1.1

17.09

18.78

u/l

0.18

114

673

Alzheimer disease, including avohilmo

492

0.60

2.71

1.0

1.1

44.69

32.08

u/l

0.44

350

L02BA Anti-estrogens

356

1.58

2.71

1.2

1.1

24.08

21.55

u/l

0.13

274

Use of memantine

379

0.50

2.71

1.0

1.1

35.35

33.83

u/l

0.04

269

Use of other anti-dementia drugs

379

0.50

2.71

1.0

1.1

35.35

33.83

u/l

0.04

269

Bipolar affective disorders

294

1.64

2.70

1.2

1.1

45.59

18.81

u/l

0.41

236

Alzheimer’s disease, wide definition

340

0.49

2.67

1.1

64.62

31.76

u/l

0.57

241

Other benign neoplasms of skin

646

1.41

2.67

1.2

1.1

19.29

21.30

u/l

0.28

481

Colorectal adenocarcinoma, excluding all cancers (controls excluding all cancers)

303

1.62

2.66

1.1

31.70

24.35

u/l

0.36

217

Other viral diseases

485

1.48

2.65

1.1

28.39

21.84

u/l

0.62

374

Other renal tubulo-interstitial diseases

3.15

2.65

1.1

24.00

24.44

u/l

—

Heartburn

147

1.91

2.65

1.2

1.1

10.13

25.87

u/l

2.39

106

Follicular lymphoma, hilmo

2.40

2.63

1.1

30.36

28.23

u/l

0.07

116

804

1.36

2.62

1.2

1.1

26.61

27.60

u/l

0.09

586

Dorsopathies

310

1304

1.21

2.62

1.1

26.97

25.34

u/l

0.11

240

999

Corneal ulcer

305

1.61

2.60

1.2

1.1

18.09

25.67

u/l

0.95

234

Other inflammation of eyelid

229

1.71

2.58

1.2

1.1

15.78

27.83

u/l

1.55

172

Actinic keratosis

107

741

1.37

2.58

1.2

1.1

28.79

28.80

u/l

0.00

533

Squamous cell neoplasms and carcinomas of the skin, excluding all cancers (controls excluding all cancers)

170

1.83

2.57

1.2

1.1

26.96

25.67

u/l

0.06

120

Malignant melanoma

260

1.66

2.56

1.3

1.1

26.97

33.70

u/l

0.34

197

Other malignant neoplasms of skin (=non-melanoma skin cancer), excluding all cancers (controls excluding all cancers)

127

649

1.34

2.56

1.2

1.1

29.74

22.60

u/l

0.75

101

479

Personality disorders

459

1.48

2.53

1.2

1.1

44.67

18.99

u/l

0.52

365

350

1.54

2.53

1.2

1.1

29.77

34.40

u/l

0.28

249

Mental and behavioural disorders due to alcohol, excluding acute intoxication

116

861

1.35

2.52

1.1

51.02

24.49

u/l

1.03

647

Melanocytic naevi

460

1.48

2.51

1.3

1.1

19.81

19.83

u/l

0.00

349

Erosion of teeth, including avohilmo

359

1.54

2.49

1.2

1.1

22.50

26.84

u/l

0.24

283

Acute alcohol intoxication, ICD10

301

1.60

2.49

1.1

32.71

25.43

u/l

0.44

233

Calculus of kidney and ureter

568

1.43

2.49

1.1

24.55

30.47

u/l

0.48

433

Allergic contact dermatitis

232

1.69

2.48

1.2

1.1

17.49

19.01

u/l

0.15

179

Skin changes due to chronic exposure to nonionizing radiation

109

761

1.36

2.46

1.2

1.1

28.24

28.28

u/l

0.00

551

Pre-eclampsia or eclampsia

454

1.48

2.46

1.2

23.17

20.36

u/l

0.18

362

Benign neoplasm: Adrenal gland

109

2.03

2.46

1.1

47.68

26.09

u/l

0.37

Carpal tunnel syndrome

182

1301

1.26

2.45

1.1

26.87

25.58

u/l

0.11

138

1013

Bronchitis, not specified as acute or chronic

123

1.96

2.45

1.1

26.75

28.87

u/l

0.05

Other headache syndromes

117

875

1.34

2.45

1.2

1.1

19.55

23.80

u/l

0.67

692

Obesity related asthma

696

1.38

2.44

1.1

16.21

26.95

u/l

2.56

541

Fracture at wrist and hand level

603

1.41

2.44

1.1

35.23

27.89

u/l

0.27

465

Alzheimer’s disease (Late onset)

302

0.48

2.43

1.1

73.00

33.13

u/l

—

217

Atopic dermatitis, strict definition

478

1.46

2.43

1.2

1.1

15.59

17.10

u/l

0.16

375

COPD-related respiratory insufficiency

181

1.77

2.43

1.2

1.1

22.00

36.61

u/l

1.01

133

Etanercept

2.09

2.43

1.2

1.1

54.85

24.28

u/l

0.42

Spinal stenosis

155

942

1.29

2.43

1.2

1.1

25.25

26.71

u/l

0.12

119

714

Procreative management

522

1.41

2.42

1.2

1.1

22.16

18.84

u/l

0.28

395

Type1 diabetes, definitions combined, early onset

2.23

2.41

1.2

1.1

10.44

17.29

u/l

—

Other predominantly sexually transmitted diseases, not elsewhere classified

257

1.64

2.41

1.1

28.81

17.31

u/l

0.45

208

Epilepsy

562

1.42

2.40

1.1

32.36

26.14

u/l

0.30

428

Other congenital malformations of skin

2.36

2.39

1.0

1.2

30.43

24.58

u/l

—

Other pulmonary heart/vessel disease

2.36

2.39

1.1

28.33

24.09

u/l

—

Symptoms and signs involving speech and voice

691

1.38

2.38

1.1

18.10

26.22

u/l

1.50

527

Urolithiasis

624

1.40

2.37

1.1

23.79

29.78

u/l

0.53

473

Benign neoplasm: Small intestine

2.43

2.37

1.1

24.00

18.71

u/l

—

Squamous cell neoplasms and carcinomas of the skin

175

1.78

2.37

1.2

1.1

26.96

36.63

u/l

0.52

124

Pathological resorption of teeth

2.63

2.36

1.3

1.2

13.83

30.29

u/l

—

115

856

1.33

2.36

1.1

25.08

26.00

u/l

0.07

663

Undetermined asthma

205

1.71

2.36

1.1

14.37

26.48

u/l

1.41

145

Lymphoid leukaemia

2.26

2.34

1.0

1.1

51.80

28.73

u/l

—

Pollen allergy

264

1.61

2.34

1.1

14.63

17.88

u/l

0.36

209

Umbilical hernia

468

1.46

2.33

1.2

1.1

34.71

29.95

u/l

0.15

350

Asthma-related infections

159

1230

1.27

2.31

1.1

26.48

25.40

u/l

0.08

116

948

Asthma, hospital admission 2, infections

159

1230

1.27

2.31

1.1

26.48

25.40

u/l

0.08

116

948

Other/unspecified synovitis and tenosynovitis

200

1.70

2.27

1.1

20.26

26.89

u/l

0.55

153

Other disorders of the musculoskeletal system and connective tissue

262

1.61

2.25

1.3

1.1

26.88

28.10

u/l

0.06

191

Antenatal screening

268

0.57

2.25

1.0

1.1

15.82

18.44

u/l

0.17

208

Colon adenocarcinoma, excluding all cancers (controls excluding all cancers)

171

1.76

2.24

1.1

33.91

25.00

u/l

0.28

118

Benign neoplasm of eye and adnexa

149

1.82

2.24

1.0

1.1

33.48

23.86

u/l

0.27

106

Diseases of middle ear and mastoid

142

905

1.29

2.21

1.2

1.1

27.41

25.00

u/l

0.15

124

694

Migraine

125

814

1.31

2.21

1.2

1.1

17.96

20.62

u/l

0.39

634

Obsessive-compulsive disorder

2.20

2.21

1.1

18.35

18.95

u/l

0.02

Intestinal adhesions without obstruction

121

1.91

2.20

1.1

28.35

30.44

u/l

0.06

Artrosis, including avohilmo

253

1146

1.21

2.20

1.1

27.41

25.79

u/l

0.10

194

887

Early onset COPD

450

1.45

2.18

1.2

1.1

23.54

31.96

u/l

0.75

344

Pre-eclampsia or poor fetal growth

608

1.38

2.17

1.2

1.1

20.62

18.71

u/l

0.15

480

Sulfonylureas

102

607

1.34

2.16

1.1

32.83

27.55

u/l

0.33

440

Malignant neoplasm of intrahepatic ducts, biliary tract and gallbladder, excluding all cancers (controls excluding all cancers)

2.17

2.14

1.1

54.27

29.47

u/l

0.42

Nonorganic sleeping disorders, excluding more controls

258

1.59

2.14

1.1

33.68

21.59

u/l

0.33

206

Benign neoplasm of other and unspecified endocrine glands

227

1.63

2.14

1.2

1.1

31.69

28.18

u/l

0.09

169

Other anxiety disorders

108

723

1.33

2.13

1.2

1.1

39.19

18.64

u/l

0.82

565

Benign neoplasm: Skin of other and unspecified parts of face

159

1.77

2.13

1.1

13.17

21.87

u/l

1.15

110

Conjunctivitis

204

1452

1.23

2.12

1.2

1.1

23.40

25.27

u/l

0.17

167

1121

Seborrhoeic keratosis

428

1.45

2.12

1.2

1.1

23.83

29.01

u/l

0.40

316

Alcohol use disorder, ICD-based

106

802

1.32

2.10

1.1

53.58

23.85

u/l

1.06

605

Vasomotor and allergic rhinitis

100

739

1.33

2.10

1.1

18.57

23.73

u/l

0.52

569

Phlebitis and thrombophlebitis (not including DVT)

454

1.43

2.09

1.2

1.1

29.73

26.14

u/l

0.16

343

Disorders of breast

148

1084

1.27

2.09

1.1

17.43

22.36

u/l

0.69

109

857

Restless leg syndrome

213

1.65

2.09

1.0

1.1

18.38

26.17

u/l

0.65

160

Spontaneous rupture of synovium and tendon

138

1.82

2.09

1.0

1.1

44.53

27.66

u/l

0.28

109

Colonic or urogenital fistula

530

1.40

2.08

1.1

21.95

27.21

u/l

0.46

404

Peritonsillar abscess

332

1.51

2.07

1.1

21.24

23.22

u/l

0.14

255

Acute laryngitis and tracheitis

136

1.81

2.07

1.1

28.88

15.56

u/l

0.35

107

Other intervertebral disc disorders

243

1234

1.21

2.07

1.2

1.1

20.87

25.71

u/l

0.84

194

951

Other keratitis

168

1.73

2.07

1.2

1.1

18.25

22.71

u/l

0.40

125

Use of anticholinesterases

502

0.64

2.07

1.0

1.1

42.86

31.73

u/l

0.36

355

N06DA Anticholinesterases

502

0.64

2.07

1.0

1.1

42.86

31.73

u/l

0.36

355

Schizophrenia or delusion, excluding more controls

510

1.40

2.06

1.2

1.1

17.57

21.02

u/l

0.37

406

Papillary adenocarcinoma of thyroid gland, excluding all cancers (controls excluding all cancers)

103

1.95

2.05

1.3

1.1

13.58

15.68

u/l

0.19

Diplopia

222

1.63

2.05

1.2

1.1

16.70

29.46

u/l

1.37

167

Contusion of ankle

2.33

2.05

1.2

1.1

37.57

23.62

u/l

—

Other bacterial agents as the cause of diseases classified to other chapters

4.05

2.04

1.5

1.1

24.50

38.77

u/l

—

Disorders of adult personality and behaviour

490

1.41

2.04

1.2

1.1

43.23

19.79

u/l

0.45

390

Other hammer toe(s) (acquired)

335

1.49

2.04

1.1

21.69

24.41

u/l

0.26

256

Other bursopathies

238

1.60

2.04

1.3

1.1

15.47

27.05

u/l

1.81

176

Asthma-related pneumonia

693

1.34

2.03

1.1

31.43

27.41

u/l

0.20

517

Dislocation, sprain and strain of joints and ligaments at wrist and hand level

507

1.40

2.03

1.1

19.75

21.00

u/l

0.09

397

Asthma (diagnoses ohter than nonallergic)

243

1735

1.20

2.03

1.1

21.06

25.53

u/l

0.72

179

1336

Behavioural syndromes associated with physiological disturbances and physical factors

532

1.39

2.03

1.1

26.41

21.39

u/l

0.23

412

conjunctival haemorrhage

125

1.85

2.02

1.1

11.29

31.05

u/l

3.07

Visual disturbances and blindness

138

1088

1.27

2.02

1.2

1.1

28.97

24.84

u/l

0.16

104

837

Benign neoplasm: Small intestine

2.23

2.01

1.1

24.00

22.80

u/l

—

Transient ischemic attack

144

944

1.27

2.01

1.1

37.07

23.86

u/l

0.61

713

Personal history of other diseases and conditions

132

1.81

2.00

1.2

1.1

18.47

18.20

u/l

0.01

106

Malignant neoplasm of bladder

1.96

2.00

1.2

1.1

13.93

37.44

u/l

2.22

Myocardial infarction, with ST-elevation

287

1.54

1.99

1.1

23.57

32.71

u/l

0.73

211

Asthma-related pneumonia or sepsis

696

1.34

1.99

1.1

31.43

27.31

u/l

0.21

520

Asthma, hospital admissions 3, pneumonia

696

1.34

1.99

1.1

31.43

27.31

u/l

0.21

520

Persistent mood disorders

352

1.48

1.98

1.2

1.1

20.37

26.04

u/l

0.47

270

Vasomotor rhinitis (mode)

126

1.83

1.98

1.0

1.2

13.11

23.28

u/l

1.50

Valvular operations

201

1.65

1.98

1.2

1.1

38.72

31.59

u/l

0.29

147

Other and unspecified drugs and medicaments

126

1.83

1.98

1.1

10.39

26.24

u/l

2.48

Amyloidosis, other/unspecified

3.36

1.97

1.0

32.71

29.49

u/l

—

Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

139

1079

1.26

1.95

1.1

22.93

26.11

u/l

0.13

112

823

Generalized anxiety disorder

202

1.64

1.94

1.1

10.54

17.16

u/l

1.54

166

Glaucoma

161

1139

1.24

1.94

1.2

1.1

23.89

26.61

u/l

0.31

108

872

Use of pramipexole

437

1.42

1.93

1.1

21.74

29.85

u/l

0.77

330

Dementia

634

0.72

1.93

1.1

28.80

31.04

u/l

0.13

455

Panic disorder

203

1.63

1.91

1.1

10.26

17.11

u/l

1.77

167

Alzheimer’s disease (Late onset), excluding more controls

189

0.49

1.91

1.0

1.1

46.67

27.92

u/l

—

133

FESS (DNB20)

211

1.62

1.91

1.1

25.86

22.86

u/l

0.12

164

Excessive, frequent and irregular menstruation

112

477

1.31

1.90

1.2

1.1

13.30

22.33

u/l

2.28

368

Covid-19 suspected case

346

0.55

1.90

1.2

1.1

18.46

21.05

u/l

0.11

274

Papillary adenocarcinoma of thyroid gland

2.01

1.90

1.4

1.1

14.36

27.16

u/l

1.27

Temporomandibular joint disorders, including avohilmo

111

858

1.29

1.90

1.2

1.1

28.00

20.71

u/l

0.50

672

Use of disulfiram, acamprosate or naltrexone

128

1.80

1.89

1.0

1.1

13.31

24.15

u/l

1.36

Malignant neoplasm of thyroid gland

121

1.83

1.88

1.3

1.1

14.13

24.63

u/l

1.31

Injury of eye and orbit

212

1.61

1.87

1.1

99.10

27.34

u/l

0.76

164

Reactive arthropathies

136

1.77

1.87

1.1

82.37

26.72

u/l

0.46

Hodgkin lymphoma

2.66

1.86

1.1

55.67

17.40

u/l

—

Lymphoid leukaemia

2.03

1.85

1.0

1.1

51.80

32.32

u/l

—

Wet age-related macular degeneration

279

1.52

1.85

1.0

1.1

30.81

35.49

u/l

0.25

200

Infective bursitis

2.58

1.80

1.4

1.2

18.11

25.84

u/l

—

Other blood glucose lowering drugs, excl. Insulins

311

1.48

1.79

1.0

1.1

26.21

26.64

u/l

0.03

230

Unspecified fall

124

974

1.26

1.79

1.2

1.1

31.22

27.06

u/l

0.22

102

743

Triptan medication for migraine, single purchase ok

215

1216

1.20

1.78

1.1

22.77

24.83

u/l

0.19

166

953

Migraine, single triptan purchase ok & required. ICD-code if available is included

215

1216

1.20

1.78

1.1

22.77

24.83

u/l

0.19

166

953

Any dementia

555

0.71

1.77

1.1

40.22

31.09

u/l

0.39

404

Nontoxic single thyroid nodule

131

1.76

1.77

1.1

1.2

18.41

25.02

u/l

0.46

Unspecified mental disorder

104

807

1.29

1.77

1.2

1.1

17.60

26.36

u/l

1.42

646

Infection due to other mycobacteria

3.36

1.75

1.2

1.1

6.33

10.43

u/l

—

Paroxysmal tachycardia

319

1.43

1.75

1.1

22.25

17.47

u/l

0.56

254

Parodontitis, under 40 years

1.98

1.74

1.3

1.2

14.10

14.47

u/l

—

Retinal detachments and breaks

713

1.31

1.74

1.2

1.1

23.06

26.54

u/l

0.23

528

Other abnormal immunological findings in serum

2.68

1.72

1.1

1.0

17.00

30.26

u/l

—

Coxarthrosis, primary, with hip surgery

132

1003

1.25

1.72

1.1

23.31

25.67

u/l

0.21

755

Delirium, not induced by alcohol and other psychoactive substances

170

1.65

1.72

1.2

1.1

22.21

33.04

u/l

0.68

126

Amputation of thigh

2.93

1.72

1.3

1.1

22.00

55.50

u/l

—

Benign neoplasm: Adrenal gland

125

1.77

1.72

1.1

47.68

23.05

u/l

0.44

Other contact dermatitis

125

1.76

1.71

1.4

1.1

29.53

23.49

u/l

0.32

Paralytic strabismus

103

1.85

1.71

1.1

31.54

28.85

u/l

0.05

Superficial injury of abdomen, lower back and pelvis

226

1.55

1.70

1.1

18.43

26.56

u/l

0.72

172

Cardiodefibrillation

741

1.30

1.70

1.1

34.65

31.29

u/l

0.16

548

Alcohol abuse, main dg

234

1.54

1.70

1.1

34.83

26.61

u/l

0.39

178

Social phobias

1.91

1.69

1.2

1.1

17.71

18.30

u/l

0.02

Parodontitis, under 40 years, or operation codes

1.95

1.69

1.3

1.2

14.10

14.40

u/l

—

Fracture of skull and facial bones

332

1.45

1.69

1.2

1.1

43.47

24.25

u/l

0.66

257

Benign neoplasm: Rectum, anus and anal canal

382

1.42

1.69

1.2

1.1

19.30

31.47

u/l

1.83

288

Fracture of shoulder and upper arm

708

1.30

1.68

1.2

1.1

36.24

25.11

u/l

0.51

531

Other female pelvic inflammatory diseases

342

1.44

1.65

1.2

22.98

20.92

u/l

0.09

260

Delivery, wide proxy

421

0.72

1.64

1.2

1.1

21.83

28.46

u/l

0.43

318

Cluster headache, strict, including avohilmo

1.98

1.64

1.2

1.1

12.50

25.24

u/l

—

Parodontitis, under 40 years and operation codes

1.98

1.64

1.3

1.2

10.78

15.11

u/l

—

Parodontitis, operation under 40 years and operation codes

1.98

1.64

1.3

1.2

10.78

15.11

u/l

—

Injuries to the neck

376

1.41

1.64

1.1

17.31

23.37

u/l

0.77

297

Use of eye-antiallergens (taken as indicator of allergic/atopic conjunctivitis)

144

1154

1.23

1.64

1.2

1.1

24.93

22.36

u/l

0.19

122

900

Superficial injury of forearm

127

1.74

1.63

1.2

1.1

19.10

22.05

u/l

0.18

Unspecified chronic bronchitis

2.25

1.63

1.3

1.1

30.17

30.68

u/l

—

Other arthrosis

143

830

1.23

1.63

1.1

26.10

25.39

u/l

0.06

111

638

Ethmoidectomy

221

1.54

1.61

1.1

25.86

22.51

u/l

0.14

173

Reactive arthropathies, FINNGEN

1.84

1.61

1.1

111.69

20.66

u/l

0.56

Superficial injury of wrist and hand

311

1.45

1.60

1.1

20.85

22.75

u/l

0.14

247

Sleep disorders

361

1.41

1.60

1.1

29.11

23.05

u/l

0.19

278

Arterial embolism and thrombosis of lower extremity artery

2.33

1.60

1.1

1.2

60.60

30.52

u/l

—

Congenital malformations of the circulatory system

199

1.56

1.60

1.2

1.1

10.79

23.56

u/l

2.82

153

Kela-code for severe mental illness

715

1.29

1.58

1.1

18.42

26.66

u/l

1.11

569

Other coagulation defects

106

1.80

1.58

1.2

1.1

65.17

26.64

u/l

0.30

Extrapyramidal and movement disorders

760

1.28

1.57

1.1

18.61

26.88

u/l

1.67

572

Other symptoms and signs involving cognitive functions and awareness

120

904

1.25

1.57

1.1

31.43

25.86

u/l

0.39

693

Polyuria

388

1.39

1.56

1.1

17.12

25.54

u/l

1.43

281

COPD

121

801

1.25

1.56

1.2

1.1

25.49

29.19

u/l

0.35

589

Other condition

215

1.54

1.56

1.2

1.1

47.26

22.88

u/l

0.50

159

Asthma, including avohilmo

334

1698

1.14

1.56

1.1

19.82

25.70

u/l

1.29

249

1309

Other chronic obstructive pulmonary disease

117

779

1.25

1.55

1.2

1.1

23.25

29.75

u/l

0.85

570

Benign neoplasm of eye and adnexa

168

1.61

1.55

1.0

1.1

33.48

28.06

u/l

0.14

125

Hyperfunction of pituitary gland

2.04

1.54

1.2

11.75

24.75

u/l

—

Colon adenocarcinoma

192

1.57

1.53

1.1

33.91

33.38

u/l

0.01

138

Intracerebral haemorrhage

192

1.57

1.53

1.3

1.1

60.22

24.89

u/l

0.58

146

Vitiligo

3.36

1.52

1.2

1.1

10.40

48.67

u/l

—

Cardiomyopathy

265

1.47

1.52

1.1

19.21

30.56

u/l

1.04

189

Alzheimer’s disease, wide definition, excluding more controls

203

0.57

1.52

1.0

1.1

44.17

26.63

u/l

0.37

145

Allergic conjunctivitis

150

1220

1.21

1.52

1.2

1.1

24.40

21.79

u/l

0.20

126

946

Malignant melanoma of skin, excluding all cancers (controls excluding all cancers)

233

1.51

1.2

1.1

23.00

24.60

u/l

0.08

169

Diseases of male genital organs

115

463

1.26

1.49

1.1

20.66

35.28

u/l

2.07

351

Angina pectoris

161

903

1.20

1.48

1.1

29.53

23.11

u/l

0.50

118

685

Malignant neoplasm of colon

259

1.47

1.1

38.68

33.87

u/l

0.15

190

Acetic acid derivatives and related substances

300

1.32

1.45

1.1

1.2

35.76

28.54

u/l

0.23

222

Other disorders of breast

252

1.47

1.44

1.1

1.2

18.15

22.02

u/l

0.33

191

Benign neoplasm: Sigmoid colon

352

1.39

1.44

1.3

1.1

28.04

32.35

u/l

0.14

266

Cluster headache, wide,, including avohilmo

1.88

1.44

1.2

1.1

12.50

25.20

u/l

—

Colorectal adenocarcinoma

352

1.39

1.44

1.1

31.70

31.68

u/l

0.00

258

Insomnia

244

1.48

1.44

1.1

33.11

19.65

u/l

0.32

188

Donors of organs and tissues

2.75

1.44

1.2

1.1

42.50

30.25

u/l

—

Haemorrhage in early pregnancy

611

0.72

1.43

1.1

20.53

19.47

u/l

0.05

489

Colorectal cancer

438

1.35

1.43

1.1

35.14

31.87

u/l

0.14

319

Coxarthrosis, primary

166

1209

1.19

1.43

1.1

23.15

28.44

u/l

0.66

126

913

Toxic effects of substances chiefly nonmedicinal as to source

164

1.59

1.43

1.2

1.1

23.59

23.11

u/l

0.02

123

Rash and other nonspecific skin eruption

172

1.57

1.42

1.2

1.1

14.21

22.45

u/l

1.00

128

Cardiac murmurs and other cardiac sounds

124

1.68

1.41

1.2

1.1

23.44

21.74

u/l

0.09

Synovial cyst of popliteal space [Baker]

118

1.70

1.41

1.3

1.2

15.17

26.59

u/l

1.03

Postmenopausal atrophic vaginitis

387

1.29

1.40

1.1

19.33

24.55

u/l

0.49

294

Mixed conductive and sensorineural hearing loss

213

1.51

1.40

1.2

1.1

17.65

31.65

u/l

1.74

153

Haemangioma and lymphangioma, any site

126

1.67

1.40

1.0

1.1

13.21

16.97

u/l

—

Leiomyoma of uterus

193

932

1.18

1.38

1.2

1.1

24.13

21.69

u/l

0.24

153

721

Nummular dermatitis

119

1.68

1.37

1.2

1.1

29.42

33.50

u/l

0.16

Focal epilepsy, strict definition

322

1.40

1.37

1.2

1.1

31.00

28.89

u/l

0.09

242

Other nonscarring hair loss

2.97

1.36

1.0

1.3

86.60

49.42

u/l

—

Phakomatoses, not elsewhere classified

2.96

1.36

1.2

1.1

51.38

40.98

u/l

—

Psychotic depression

1.83

1.35

1.1

51.00

27.44

u/l

—

Nonsuppurative otitis media

278

1.40

1.35

1.2

1.1

22.14

18.97

u/l

0.29

207

Inflammatory diseases of prostate (prostatitis)

199

1.51

1.34

1.1

19.40

42.81

u/l

1.90

150

Hodgkin lymphoma, hilmo

2.15

1.34

1.1

55.67

25.54

u/l

—

Any dementia, excluding more controls

501

0.75

1.32

1.1

33.29

28.36

u/l

0.26

365

Malignant neoplasm of digestive organs

759

1.25

1.31

1.1

44.80

26.41

u/l

1.37

548

Otitis externa, unspecified

160

1.57

1.31

1.2

1.1

28.63

24.13

u/l

0.13

123

Emotionally unstable personality disorder

168

1.55

1.31

1.4

1.1

11.31

19.47

u/l

1.58

137

Other disorders of bone

334

1.38

1.30

1.2

1.1

27.02

19.34

u/l

0.53

255

Use of donepezil

307

0.63

1.30

1.0

1.1

51.36

33.27

u/l

0.28

220

Amyloidosis

2.37

1.29

1.0

1.1

160.75

20.35

u/l

—

Allergic contact dermatitis due to drugs in contact with skin

2.37

1.29

1.3

1.1

18.00

31.12

u/l

—

Eating disorders

129

1.63

1.29

1.1

20.89

19.89

u/l

0.04

106

Nontoxic multinodular goitre

412

1.34

1.28

1.1

16.51

26.47

u/l

1.88

313

Fall on and from stairs and steps

482

1.31

1.28

1.1

20.35

26.50

u/l

0.74

368

Other chronic obstructive pulmonary disease, including avohilmo

140

974

1.20

1.27

1.2

1.1

23.25

28.05

u/l

0.72

104

719

Pericarditis

2.01

1.27

1.3

1.1

34.64

34.32

u/l

0.01

Other enthesopathies

641

1.27

1.2

1.1

18.75

26.82

u/l

0.61

494

Dental caries 2, only avohilmo

198

1345

1.16

1.26

1.1

20.34

24.20

u/l

0.36

151

1054

Other/unspecified dorsalgia

102

825

1.23

1.26

1.2

1.1

21.09

24.56

u/l

0.36

642

Benign neoplasm: Skin of other and unspecified parts of face

186

1.51

1.26

1.1

13.17

30.31

u/l

3.05

134

Ganglion

405

1.34

1.26

1.1

21.73

23.51

u/l

0.10

316

Migraine without aura

328

1.37

1.25

1.1

19.85

17.66

u/l

0.25

263

Benign neoplasm: Tongue

2.23

1.24

1.0

1.1

33.89

17.91

u/l

—

Coronary artery bypass grafting

387

1.30

1.23

1.2

1.1

32.22

27.51

u/l

0.29

291

Injuries to the shoulder and upper arm

224

1637

1.15

1.23

1.2

1.1

31.59

25.17

u/l

0.52

169

1253

Schizophrenia, schizotypal and delusional disorders

574

1.27

1.22

1.2

1.1

17.26

22.05

u/l

0.59

446

Malignant melanoma of skin

188

1.49

1.21

1.2

1.1

22.26

30.01

u/l

0.39

139

Ménière disease

180

1.50

1.20

1.1

26.03

26.44

u/l

0.02

127

Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

2.32

1.19

1.0

1.2

22.05

20.90

u/l

—

Visual disturbances

120

1000

1.20

1.18

1.2

1.1

31.76

24.94

u/l

0.24

770

Bell's palsy

189

1.48

1.18

1.1

17.24

23.74

u/l

0.52

140

Toxic effect of ethanol

1.88

1.18

1.3

1.1

15.29

27.09

u/l

—

Other disorders of veins

110

909

1.21

1.18

1.1

22.06

24.71

u/l

0.31

715

Other specified and unspecified personality disorders

125

1.60

1.17

1.3

1.1

102.71

22.80

u/l

0.52

Poisoning by medicine, drug-induced

0.00

1.16

0.0

1.2

—

34.87

—

Hallux rigidus

265

1.40

1.16

1.1

21.87

26.54

u/l

0.29

191

COPD, early/later onset

117

822

1.20

1.15

1.2

1.1

23.25

30.02

u/l

0.92

607

Retained placenta and membranes, without haemorrhage

257

1.40

1.15

1.1

1.2

18.73

18.89

u/l

0.01

205

Pregnancy hypertension

112

838

1.21

1.15

1.1

1.2

18.28

19.10

u/l

0.08

666

Anomalies of pupillary function

0.00

1.14

0.0

1.1

—

27.45

—

Schizophrenia or delusion

571

1.26

1.14

1.2

1.1

17.57

21.91

u/l

0.49

444

COPD, hospital admissions

116

818

1.20

1.13

1.2

1.1

23.25

30.10

u/l

0.94

603

Lesion of lateral popliteal nerve

1.85

1.13

1.0

1.1

14.57

31.91

u/l

—

Nontoxic goitre/thyroid nodule

661

1.24

1.13

1.1

16.85

23.75

u/l

1.53

509

Oral lichen ruber planus wide, hypothyreosis or thyroxin

103

1.66

1.12

1.1

1.2

13.67

22.80

u/l

1.19

Adhesive capsulitis of shoulder

335

1.35

1.12

1.3

1.1

11.10

27.03

u/l

3.55

256

Nontraumatic intracranial haemmorrhage

361

1.33

1.12

1.3

1.1

50.38

25.96

u/l

0.65

280

Abnormal findings on diagnostic imaging of central nervous system

1.90

1.12

1.4

1.1

23.32

22.07

u/l

0.04

Heterophoria

111

1.62

1.12

1.1

22.52

24.15

u/l

0.05

Transport accidents

111

819

1.20

1.11

1.2

1.1

33.02

22.93

u/l

0.56

636

Injuries to unspecified part of trunk, limb or body region

143

1.54

1.11

1.1

14.06

26.64

u/l

1.88

104

Lung diseases due to external agents

217

1.43

1.11

1.2

1.1

31.43

34.00

u/l

0.10

158

Rotator cuff syndrome

167

1068

1.16

1.10

1.2

1.1

22.63

26.51

u/l

0.43

134

813

Injury, poisoning and certain other consequences of external causes

154

657

1.18

1.10

1.1

23.85

20.59

u/l

0.37

122

501

Endometriosis of ovary

327

1.34

1.10

1.1

36.69

20.05

u/l

0.77

256

Sequelae of infectious and parasitic diseases

112

1.61

1.08

1.2

1.1

26.81

24.38

u/l

0.08

Secondary polycythaemia

2.20

1.08

1.1

1.2

34.94

23.07

u/l

—

Other and unspecified nerve root and plexus disorders, also in other diseases

329

1.34

1.08

1.2

1.1

11.68

22.26

u/l

3.72

254

Alzheimer disease, excluding more controls

228

0.67

1.08

1.0

1.1

45.00

25.82

u/l

0.57

162

Congenital malformations of heart and great arteries

179

1.46

1.08

1.2

1.1

21.38

21.85

u/l

0.02

137

Diaphragmatic hernia

783

1.21

1.07

1.1

22.06

24.95

u/l

0.32

581

Disorders of ocular muscles, binocular movement, accommodation and refraction

114

948

1.19

1.07

1.1

20.35

23.92

u/l

0.37

740

Obstructed labour due to malposition and malpresentation of fetus

392

1.30

1.07

1.2

1.1

13.64

18.82

u/l

0.87

321

Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

125

924

1.18

1.07

1.1

1.2

17.62

20.45

u/l

0.35

737

Hernia

262

1581

1.12

1.07

1.1

30.91

25.15

u/l

0.61

217

1196

Malignant neoplasm of corpus uteri, excluding all cancers (controls excluding all cancers)

169

1.48

1.07

1.2

1.1

24.36

20.84

u/l

0.15

114

D07AA Corticosteroids, weak (group I)

236

1.40

1.05

1.2

1.1

20.06

21.92

u/l

0.07

184

Dental caries 2 and operation codes

195

1356

1.14

1.05

1.1

20.14

24.18

u/l

0.38

150

1064

Single spontaneous delivery

525

0.81

1.05

1.1

1.2

18.57

28.07

u/l

1.18

402

Focal epilepsy

357

1.32

1.04

1.2

1.1

29.91

27.78

u/l

0.09

275

HSIL lesion of the cervix uteri, vagina or vulva

340

1.33

1.04

1.2

19.81

17.19

u/l

0.31

274

Disorders of optic nerve and visual pathways

146

1.51

1.03

1.2

1.1

33.85

24.65

u/l

0.19

111

Cardiomyopathy, other and unspecified

106

1.61

1.02

1.0

1.1

16.83

36.01

u/l

0.94

Primary open-angle glaucoma, strict

543

1.25

1.02

1.2

1.1

20.68

29.96

u/l

1.36

405

Dementia, including avohilmo

675

0.82

1.01

1.1

27.80

30.38

u/l

0.17

481

Bitten or struck by other mammals

155

1.49

1.00

1.0

1.1

26.29

20.03

u/l

0.24

123

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence

194

1.41

1.00

1.2

15.75

15.84

u/l

0.00

153

Other disorders of eyelid

120

985

1.18

0.99

1.1

20.09

26.63

u/l

1.07

752

Nonorganic sleeping disorders

308

1.33

0.99

1.1

33.68

22.95

u/l

0.28

240

Other fall from one level to another

343

1.31

0.99

1.1

34.79

28.56

u/l

0.18

266

COPD related to multimorbidity

688

1.20

0.99

1.2

1.1

23.73

29.96

u/l

0.80

507

Other and unspecified tonsillitis

395

1.27

0.98

1.2

1.1

20.21

26.78

u/l

0.52

311

Tonsillectomy and adenotomy

793

0.83

0.98

1.1

18.39

20.59

u/l

0.15

616

Hypersomnia

2.18

0.98

1.0

1.1

20.50

43.87

u/l

—

Toxic liver disease

2.18

0.98

1.0

73.60

35.49

u/l

—

Unspecified acute lower respiratory infection

206

1.41

0.98

1.1

52.20

24.09

u/l

0.84

156

Noninflammatory disorders of female genital tract

114

482

1.19

0.98

1.1

18.75

22.14

u/l

0.39

372

Salpingitis and oophoritis

432

1.28

0.97

1.1

1.2

28.73

21.45

u/l

0.34

340

Deforming dorsopathies

602

1.23

0.97

1.2

1.1

18.91

24.99

u/l

1.00

464

Malignant neoplasm of skin

165

1082

1.15

0.97

1.2

1.1

28.64

25.61

u/l

0.29

129

805

Complications of genitourinary prosthetic devices, implants and grafts

1.95

0.97

1.6

1.1

11.43

32.46

u/l

—

Other specified/unspecified disorders of bone/cartilage

1.95

0.97

1.0

1.1

15.57

15.03

u/l

—

Strabismus

485

1.26

0.97

1.1

21.63

22.86

u/l

0.07

371

Torsion of testis

0.00

0.96

0.0

1.1

—

13.48

—

Sequelae of injuries, of poisoning and of other consequences of external causes

433

1.27

0.96

1.1

28.85

23.20

u/l

0.22

331

Dental caries 2

198

1374

1.13

0.96

1.1

20.51

24.04

u/l

0.32

151

1078

Chronic sinusitis

110

932

1.18

0.95

1.1

20.05

25.56

u/l

0.76

722

Enthesopathies of lower limb, excluding foot

461

1.26

0.94

1.2

1.1

30.04

25.96

u/l

0.15

356

Supervision of normal pregnancy

256

0.74

0.94

1.0

1.1

14.77

17.92

u/l

0.28

200

Retinal detachment with retinal break

225

1.38

0.94

1.1

18.28

28.64

u/l

0.92

163

Benign neoplasm of ovary

320

1.31

0.94

1.2

1.1

27.74

18.14

u/l

0.47

236

Dislocation, sprain and strain of joints and ligaments of elbow

1.62

0.93

1.0

1.1

17.29

21.85

u/l

—

Disorder of the sleep-wake schedule

2.23

0.93

1.3

1.1

5.82

34.35

u/l

—

Complications of cardiac and vascular prosthetic devices, implants and grafts

2.23

0.93

1.2

1.1

47.17

32.78

u/l

—

Blepharochalasis

660

1.21

0.93

1.1

21.78

26.45

u/l

0.41

508

Acute and transient psychotic disorders

183

1.42

0.93

1.1

18.18

22.52

u/l

0.31

140

Spondylosis

147

1095

1.15

0.93

1.2

1.1

28.50

26.05

u/l

0.09

105

840

Disturbances of skin sensation

516

1.24

0.92

1.1

19.11

22.33

u/l

0.27

395

Other benign neoplasms of connective and other soft tissue

142

1.48

0.92

1.2

1.1

14.12

22.33

u/l

0.92

100

Alcohol dependence

481

1.25

0.91

1.1

75.48

25.64

u/l

0.91

371

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis

154

1096

1.15

0.91

1.1

17.85

22.19

u/l

0.95

119

861

Dislocation, sprain and strain of joints and ligaments at neck level

218

1.38

0.91

1.0

1.1

21.05

18.73

u/l

0.14

175

Asthma and allergy, excluding more controls

149

1.46

0.90

1.3

1.1

42.31

13.92

u/l

0.52

112

Myopia

176

1.42

0.90

1.2

1.1

21.43

18.04

u/l

0.12

140

Abrasion of teeth

419

1.23

0.90

1.2

1.1

26.73

26.98

u/l

0.01

326

Acidosis

2.08

0.89

1.2

13.83

23.63

u/l

—

Other benign neoplasms of skin

783

1.19

0.89

1.2

1.1

19.29

26.00

u/l

1.25

590

Alopecia areata

1.91

0.88

1.0

1.1

22.63

29.28

u/l

—

Allergic urticaria

119

1.52

0.88

1.2

1.1

16.00

21.91

u/l

—

Neuromuscular dysfunction of bladder

152

1.45

0.88

1.2

1.1

20.57

30.86

u/l

0.36

117

Pregnancy, childbirth and the puerperium

360

0.80

0.86

1.1

1.2

27.33

26.98

u/l

0.01

274

Fibroblastic disorders

467

1.24

0.86

1.1

29.89

31.19

u/l

0.04

345

Thoracic aortic aneurysm

212

1.37

0.86

1.1

39.23

27.71

u/l

0.49

162

Other strabismus

386

1.27

0.86

1.1

23.57

21.51

u/l

0.10

298

Oxicams

284

1.24

0.85

1.1

45.52

29.42

u/l

0.45

212

Allergic rhinitis

553

1.22

0.85

1.1

14.35

17.99

u/l

0.56

430

Delivery

525

0.84

1.1

1.2

16.86

28.07

u/l

1.60

402

Pain and other conditions associated with female genital organs and menstrual cycle

355

1.27

0.84

1.2

1.1

18.58

17.63

u/l

0.08

285

Disorders of muscles

162

1.42

0.84

1.2

1.1

20.99

26.01

u/l

0.38

126

Benign neoplasm: Tongue

1.75

0.82

1.0

1.1

33.89

28.82

u/l

—

Nasal polyp

354

0.73

0.82

1.0

1.1

27.12

31.54

u/l

0.13

266

Sciatica+with lumbago

133

1102

1.15

0.82

1.1

19.44

26.17

u/l

0.86

102

854

Primary open-angle glaucoma

662

1.19

0.82

1.2

1.1

20.17

29.68

u/l

1.73

490

Melanocytic naevi

561

1.21

0.82

1.3

1.1

19.81

24.27

u/l

0.46

434

Focal epilepsy, mode (most common among epilepsy diagnosis)

310

1.29

0.82

1.2

1.1

30.03

28.59

u/l

0.05

236

Combinations of oral blood glucose lowering drugs

553

1.21

0.81

1.0

1.1

23.73

28.80

u/l

0.45

410

Later onset COPD, excluding more controls

290

1.26

0.80

1.2

1.1

23.00

30.81

u/l

0.60

196

Varicose veins

181

1219

1.12

0.80

1.1

20.70

26.40

u/l

1.17

128

940

Female infertility

405

0.81

0.79

1.2

1.1

20.54

20.46

u/l

0.00

322

Other bursal cyst

0.00

0.79

0.0

1.1

—

31.66

—

Carcinoma in situ of other and unspecified digestive organs

1.82

0.79

1.0

1.2

8.83

18.94

u/l

—

Melanocytic naevi of upper limb, including shoulder

1.82

0.79

1.0

1.1

34.32

20.46

u/l

—

Trochanteric bursitis

268

1.31

0.79

1.2

1.1

19.86

22.93

u/l

0.15

202

Acute bronchiolitis

1.67

0.79

1.0

1.2

32.13

10.48

u/l

—

Anankastic personality disorder

1.67

0.78

1.0

1.1

10.25

24.60

u/l

—

Circumscribed brain atrophy

0.00

0.78

0.0

1.1

—

33.32

—

Aortic aneurysm

377

1.25

0.78

1.1

29.47

27.42

u/l

0.11

275

Preterm labour and delivery

592

1.20

0.78

1.1

17.35

19.75

u/l

0.27

470

Disorders of refraction and accommodation

472

1.23

0.78

1.1

1.2

17.78

22.61

u/l

0.43

360

Female infertility, cervigal, vaginal, other or unspecified origin

393

0.80

0.77

1.3

1.1

21.64

18.36

u/l

0.15

314

Monoamine oxidase A inhibitors

217

1.34

0.76

1.1

14.25

29.53

u/l

2.09

167

Degeneration of the brain due to alcohol

1.77

0.76

1.0

1.2

26.50

26.08

u/l

—

Disorders of globe

1.77

0.76

1.0

1.1

15.25

29.18

u/l

—

Blood alcohol or alcohol intoxication level

1.77

0.76

1.3

1.1

22.00

27.49

u/l

—

Acute alcohol intoxication

430

1.23

0.76

1.1

31.33

25.77

u/l

0.36

335

Chromosomal abnormalities, not elsewhere classified

0.00

0.76

0.0

1.0

—

19.36

—

Acute pharyngitis

173

1.38

0.76

1.1

17.66

17.02

u/l

0.04

134

Complications of labour and delivery

170

844

1.12

0.74

1.1

16.76

22.06

u/l

1.14

128

669

Long labour

384

1.23

0.74

1.2

9.83

17.59

u/l

2.12

308

Essential (haemorrhagic) thrombocythaemia

1.67

0.74

1.3

1.1

45.36

16.99

u/l

—

Voice disturbances

559

1.20

0.74

1.1

15.39

26.86

u/l

2.22

422

Asthma and allergy

156

1.39

0.74

1.3

1.1

42.31

15.35

u/l

0.48

115

Hydrocele

184

1.36

0.73

1.1

24.69

39.62

u/l

0.73

139

Glaucoma suspect

773

1.17

0.72

1.1

25.73

27.09

u/l

0.10

588

Basal cell carcinoma

143

1010

1.13

0.72

1.2

1.1

29.59

26.47

u/l

0.26

110

748

Other obstetric conditions, not elsewhere classified

298

1.22

0.71

1.1

1.2

21.55

14.19

u/l

0.66

247

Melanocytic naevi of scalp and neck

1.93

0.70

1.2

1.1

22.80

23.09

u/l

—

Benign neoplasm: Ascending colon

203

1.33

0.70

1.1

24.44

24.56

u/l

0.01

143

Scleritis and episcleritis

101

1.49

0.70

1.0

1.1

24.30

23.92

u/l

—

Keratoconus

1.71

0.70

1.0

1.1

19.97

27.54

u/l

—

Lumbar disc prolapse

167

1191

1.11

0.69

1.2

1.1

22.12

25.86

u/l

0.41

126

919

Non-small cell lung cancer, adenocarcinoma, excluding all cancers (controls excluding all cancers)

1.53

0.69

1.0

1.1

35.82

27.86

u/l

0.21

Other and unspecified hydrocephalus

1.86

0.68

1.0

1.1

38.80

19.57

u/l

—

Plantar fascial fibromatosis

178

1.35

0.68

1.0

1.1

13.78

21.64

u/l

0.91

137

Superficial injury of shoulder and upper arm

178

1.35

0.68

1.2

1.1

15.89

24.38

u/l

1.10

136

Asthma, hospital admissions , main diagnosis only

214

1747

1.10

0.67

1.1

19.92

25.81

u/l

0.97

158

1343

Unspecified event, undetermined intent

1.63

0.67

1.0

1.1

16.93

30.75

u/l

—

Convulsions, not elsewhere classified

343

1.24

0.66

1.0

1.1

24.00

20.01

u/l

0.25

266

Other malignant neoplasms of skin (=non-melanoma skin cancer)

138

970

1.12

0.66

1.2

1.1

29.81

26.56

u/l

0.27

107

718

Fenamates

203

1.26

0.66

1.1

1.2

17.34

29.61

u/l

1.49

157

Propionic acid derivatives

315

1.18

0.65

1.1

28.78

27.28

u/l

0.07

234

Basal cell carcinoma, including avohilmo

146

1028

1.12

0.65

1.2

1.1

29.23

26.46

u/l

0.23

113

765

Thyroiditis

128

1.41

0.65

1.1

40.43

22.83

u/l

0.29

102

Pneumonia derived septicemia

1.59

0.65

1.1

21.71

27.99

u/l

—

Other and unspecified nonorganic psychotic disorders

286

1.26

0.64

1.2

1.1

14.44

19.16

u/l

0.51

226

Maternal care related to the fetus and amniotic cavity and possible delivery problems

648

0.87

0.64

1.1

1.2

15.19

18.64

u/l

0.40

517

Tinnitus

450

1.20

0.63

1.2

1.1

24.50

28.69

u/l

0.19

334

Hallux valgus (acquired)

572

1.15

0.63

1.1

14.79

25.14

u/l

3.16

449

Asthma/COPD (KELA code 203)

247

1601

1.09

0.63

1.1

15.65

25.45

u/l

4.84

190

1237

Dislocation, sprain and strain of joints and ligaments at ankle and foot level

680

1.16

0.63

1.1

17.09

20.17

u/l

0.33

536

Cervical disc disorders

838

0.86

0.62

1.1

18.78

24.73

u/l

0.95

641

Maternal care for other known or suspected fetal problems

235

1.23

0.62

1.1

1.2

12.64

15.46

u/l

0.41

197

Chronic rhinitis, nasopharyngitis and pharyngitis

645

1.16

0.62

1.1

13.39

27.65

u/l

3.88

497

Benign neoplasm of mouth and pharynx

164

1.34

0.62

1.0

1.1

26.67

24.48

u/l

0.07

119

Viral pneumonia (known virus, not influenza)

1.67

0.61

1.6

1.2

36.60

22.90

u/l

—

Other viral infections characterized by skin and mucous membrane lesions, not elsewhere classified

1.60

0.61

1.1

20.16

30.41

u/l

—

Scoliosis

130

1.39

0.61

1.2

18.69

21.30

u/l

0.16

101

Laparoscopic right hemicolectomy

1.48

0.60

1.2

1.1

51.25

28.84

u/l

—

Malignant neoplasm of larynx, excluding all cancers (controls excluding all cancers)

0.00

0.60

0.0

1.2

—

32.17

—

Crushing injury of wrist and hand

0.00

0.60

0.0

1.1

—

30.39

—

Benign neoplasm of major salivary glands

148

1.35

0.59

1.4

1.1

25.55

22.23

u/l

0.15

104

Lichen planus

254

1.26

0.59

1.1

16.55

24.68

u/l

0.85

187

Inguinal hernia

107

814

0.89

0.59

1.1

37.28

28.59

u/l

0.50

596

Medical abortion

176

869

1.10

0.58

1.2

1.1

22.80

21.74

u/l

0.12

146

673

Degeneration of nervous system due to alcohol

1.72

0.57

1.0

1.2

26.50

26.08

u/l

—

Cardiomyopathy (excluding other)

184

1.31

0.57

1.0

1.1

13.40

34.67

u/l

2.31

136

Lichen ruber planus, wide definition including periferal and oral lichen planus

428

1.19

0.57

1.1

15.86

25.15

u/l

1.70

318

Conjunctivitis (acute, non atopic)

491

1.18

0.57

1.2

1.1

21.80

24.88

u/l

0.23

371

Other secondary gonarthrosis

1.48

0.57

1.3

1.1

22.17

19.29

u/l

0.12

Haemangioma, any site

115

1.39

0.56

1.0

1.1

9.85

17.48

u/l

—

Soft tissue disorders related to use, overuse and pressure

540

1.17

0.56

1.2

1.1

27.65

27.87

u/l

0.01

415

Excessive vomiting in pregnancy

124

1.37

0.55

1.1

12.27

19.18

u/l

0.90

Supervision of high-risk pregnancy

254

0.81

0.55

1.1

21.07

18.07

u/l

0.12

198

Cervicocranial syndrome

212

1.28

0.55

1.0

1.1

21.93

25.28

u/l

0.22

161

Thyrotoxicosis with toxic multinodular goitre

107

1.40

0.55

1.2

1.1

19.67

24.43

u/l

—

Haemangioma and lymphangioma, any site

159

1.32

0.55

1.0

1.1

13.21

24.96

u/l

—

121

Localized swelling, mass and lump of skin and subcutaneous tissue

625

1.15

0.55

1.1

27.33

25.89

u/l

0.10

473

Unstable angina pectoris

657

1.14

0.55

1.1

26.78

26.87

u/l

0.01

492

Lateral epicondylitis

257

1.25

0.55

1.1

25.80

21.24

u/l

0.11

205

False labour

359

0.84

0.54

1.1

1.2

13.75

16.74

u/l

0.26

290

Meniscus derangement

140

867

1.11

0.53

1.1

23.58

25.13

u/l

0.16

103

666

Deviated nasal septum

652

0.86

0.52

1.1

19.45

29.77

u/l

1.45

481

malignant neoplasm of female genital organs, excluding all cancers (controls excluding all cancers)

326

1.21

0.52

1.2

1.1

21.80

20.06

u/l

0.10

236

Malignant neoplasm of corpus uteri

152

1.32

0.52

1.3

1.1

21.92

21.10

u/l

0.03

109

COPD, hospital admissions 3, with asthma pneumonia sepsis

423

1.17

0.51

1.2

1.1

24.30

32.19

u/l

0.67

308

Carcinoma in situ of other and unspecified digestive organs

1.50

0.51

1.0

1.2

8.83

30.56

u/l

—

Allergic asthma (mode), excluding more controls

362

1.19

0.51

1.1

32.07

22.47

u/l

0.29

278

Contact with machinery

161

1.31

0.51

1.1

49.71

34.47

u/l

0.17

122

Dementia in Alzheimer disease

241

0.78

0.51

1.0

1.1

70.77

32.00

u/l

0.73

177

Pain in thoracic spine

287

1.22

0.51

1.1

16.00

23.68

u/l

1.07

221

Effects of foreign body entering through natural orifice

397

1.18

0.51

1.2

1.1

18.98

32.18

u/l

1.40

305

Injury of muscle and tendon at hip and thigh level

144

1.32

0.50

1.1

8.93

25.72

u/l

3.26

112

Mental and behavioural disorders due to sedatives or hypnotics

101

1.39

0.49

1.2

1.1

27.13

24.78

u/l

—

Recurring oral aphthae, including avohilmo

234

1.24

0.49

1.0

1.1

16.38

24.49

u/l

0.81

171

Diseases of appendix

188

1584

1.08

0.48

1.1

15.53

25.46

u/l

5.23

149

1223

Vestibular neuronitis

154

1.30

0.48

1.0

1.1

23.49

26.11

u/l

0.12

115

Melanocytic naevi of trunk

154

1.30

0.48

1.4

1.1

17.93

22.25

u/l

0.17

113

Mixed and other personality disorders

119

1.35

0.48

1.3

1.1

120.40

21.87

u/l

—

Other disorders of patella

317

1.20

0.48

1.1

18.27

22.51

u/l

0.35

255

COPD, hospital admission 2, with asthma infections

532

1.14

0.47

1.2

1.1

27.90

31.36

u/l

0.26

393

Caught, crushed, jammed or pinched in or between objects

1.47

0.47

1.1

80.70

26.83

u/l

—

Infections of breast associated with childbirth

1.46

0.46

1.0

1.1

11.14

25.35

u/l

—

Prolapse and hernia of ovary and fallopian tube

1.45

0.46

1.1

21.00

35.19

u/l

—

Other maternal disorders predominantly related to pregnancy

132

909

0.91

0.46

1.2

1.1

18.85

20.91

u/l

0.20

102

721

Acne

120

1.33

0.46

1.6

1.1

12.89

19.16

u/l

—

Female infertility, tubal origin

0.61

0.45

2.0

1.2

64.00

16.73

u/l

—

Antepartum haemorrhage, not elsewhere classified

119

0.67

0.45

1.0

1.3

9.63

17.69

u/l

—

100

Other spirochaetal diseases

524

1.15

0.45

1.1

19.62

26.44

u/l

1.02

392

Other acute skin changes due to ultraviolet radiation

1.40

0.45

1.3

1.1

5.86

27.81

u/l

—

Cardiomyopathies, Primary/intrinsic

174

1.27

0.44

1.0

1.1

13.59

34.46

u/l

2.03

128

Maternal care for known or suspected abnormality of pelvic organs

318

0.85

0.44

1.2

9.57

17.36

u/l

3.24

261

Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

285

1.16

0.44

1.1

1.2

21.24

14.33

u/l

0.53

237

Appendectomy

161

1433

1.08

0.44

1.2

1.1

18.34

24.89

u/l

1.15

124

1122

Pneumococcal septicemia

1.37

0.44

1.1

21.71

30.48

u/l

—

Other disorders of amniotic fluid and membranes

209

1.23

0.43

1.2

7.60

16.40

u/l

3.39

173

Foreign body on external eye

202

1.24

0.43

1.3

1.1

20.14

30.39

u/l

0.99

154

Lichen sclerosus et atrophicus

184

1.25

0.43

1.0

1.2

23.94

22.70

u/l

0.05

133

Lyme disease

517

1.14

0.43

1.1

19.50

26.75

u/l

1.09

385

Anti-inflammatory and antirheumatic products, non-steroids

315

1.13

0.42

1.1

32.91

27.28

u/l

0.29

234

Malignant neoplasm of pancreas, excluding all cancers (controls excluding all cancers)

113

1.33

0.42

1.1

114.11

24.88

u/l

—

Prepatellar bursitis

1.43

0.42

1.0

1.1

34.63

18.27

u/l

—

Use of antiglaucoma preparations and miotics

131

1.30

0.42

1.0

1.1

16.50

26.09

u/l

—

Cervicalgia

434

1.15

0.42

1.2

1.1

27.90

26.00

u/l

0.08

329

Other/unspecified enthesopathies, not elsewhere classified

149

1.28

0.41

1.1

12.43

28.01

u/l

2.42

111

Benign neoplasm of meninges

158

1.27

0.41

1.2

1.1

31.04

22.25

u/l

0.34

108

Other specified/unspecified dorsopathies

1.38

0.41

1.0

1.1

29.50

22.98

u/l

—

Carcinoma in situ of breast, lobular

0.00

0.41

0.0

1.1

—

10.80

—

Viral agents as the cause of diseases classified to other chapters

1.52

0.41

1.2

126.20

37.31

u/l

—

Benign neoplasm: Scapula and long bones of upper limb

0.00

0.41

0.0

1.1

—

32.58

—

Other injuries of upper limb, level unspecified

0.00

0.41

0.0

1.1

—

40.47

—

Frostbite

0.00

0.41

0.0

1.1

—

28.87

—

Anomalies of dental arch relationship, including avohilmo

273

1.18

0.41

1.2

1.1

15.43

18.53

u/l

0.38

216

Parkinson's disease, including avohilmo

272

0.81

0.41

1.2

1.1

21.36

33.11

u/l

0.92

203

Mouth breathing

841

1.11

0.41

1.1

14.35

28.18

u/l

4.71

648

Benign neoplasm: Parotid gland

105

1.33

0.41

1.4

1.1

18.90

24.09

u/l

—

Malignant neoplasm of brain, excluding all cancers (controls excluding all cancers)

1.36

0.41

1.4

1.1

38.63

19.63

u/l

—

Injury of nerves at lower leg level

0.00

0.40

0.0

1.1

—

43.56

—

Intracranial and intraspinal abscess and granuloma

0.00

0.40

0.0

1.1

—

26.81

—

Fall on and from ladder

114

1.32

0.40

1.1

36.34

38.29

u/l

—

Injury of intra-abdominal organs

1.47

0.40

1.2

1.1

11.08

17.25

u/l

—

Ehlers-Danlos syndrome

0.00

0.40

0.0

1.2

—

36.92

—

Fasciculation

0.00

0.40

0.0

1.1

—

35.98

—

Malignant neoplasm of larynx

0.00

0.40

0.0

1.1

—

49.80

—

Dislocation, sprain and strain of joints and ligaments of shoulder girdle

540

1.13

0.39

1.2

1.1

39.73

28.99

u/l

0.34

413

Other benign neoplasm of uterus: Corpus uteri

0.00

0.39

0.0

1.1

—

12.72

—

Migraine without aura and triptan purchases

260

1.19

0.39

1.2

20.37

17.78

u/l

0.25

216

Other and unspecified injuries of abdomen, lower back and pelvis

0.00

0.39

0.0

1.1

—

26.56

—

All dysplastic lesions of the cervix uteri, vagina or vulva

556

1.13

0.39

1.1

1.2

23.67

17.08

u/l

0.69

446

Erythema multiforme

1.39

0.38

1.2

1.1

8.00

34.10

u/l

—

Organic, including symptomatic, mental disorders

100

790

0.91

0.38

1.1

24.85

28.61

u/l

0.34

574

Non-small cell lung cancer, adenocarcinoma

1.33

0.37

1.0

1.1

35.82

33.75

u/l

0.05

Non-small cell lung cancer, adenocarcinoma, helper endpoint

1.33

0.37

1.0

1.1

35.82

33.75

u/l

0.05

Benign lipomatous neoplasm

631

0.89

0.37

1.1

14.09

27.01

u/l

2.15

479

Childhood allergy (age < 16)

110

1.27

0.36

1.4

1.2

11.75

10.80

u/l

0.05

Retinal vascular disorders

207

1.21

0.36

1.2

1.1

17.47

37.30

u/l

2.15

149

Endometriosis ASRM stages 3,4

478

1.13

0.36

1.1

1.2

34.12

20.18

u/l

0.72

376

Abnormal findings in secretions and smears from cervix uteri vagina vulva

105

898

0.92

0.36

1.1

1.2

15.41

18.71

u/l

0.70

712

Pedal cyclist injured in transport accident

385

0.86

0.35

1.2

1.1

54.30

22.94

u/l

0.59

294

Melanocytic naevi of upper limb, including shoulder

1.43

0.35

1.0

34.32

31.36

u/l

—

Other enthesopathy of foot (+metatarsalgia)

181

1.22

0.34

1.3

1.1

10.60

18.83

u/l

2.07

140

Appendicitis, broad definition

183

1576

1.06

0.33

1.2

1.1

15.25

25.53

u/l

5.51

145

1217

Abnormalities of gait and mobility

188

0.80

0.33

1.1

28.07

33.37

u/l

—

142

Generalized epilepsy, mode (most common among epilepsy diagnosis)

1.31

0.33

1.0

1.1

37.33

29.19

u/l

—

Allergic asthma (mode)

380

1.14

0.33

1.1

32.07

22.20

u/l

0.30

287

Dizziness and giddiness

192

1471

1.06

0.32

1.1

31.43

24.75

u/l

0.55

135

1145

Spondylolisthesis/Spondylolysis

388

1.13

0.32

1.1

19.57

24.15

u/l

0.48

292

Injury of muscle and tendon at lower leg level

238

1.18

0.32

1.2

1.1

28.31

28.74

u/l

0.02

183

Other obstetric trauma

1.35

0.32

1.0

1.1

7.46

16.90

u/l

—

Benign mammary dysplasia

306

0.85

0.32

1.1

11.92

24.44

u/l

3.63

231

Benign lipomatous neoplasm

502

1.12

0.32

1.1

14.09

20.58

u/l

0.86

374

Acute appendicitis

171

1519

1.06

0.32

1.1

15.90

24.98

u/l

4.19

133

1175

Other disorders of the genitourinary system

273

0.84

0.31

1.2

1.1

52.56

25.44

u/l

0.49

198

Dental caries 3 and operation codes, only avohilmo

376

1.10

0.31

1.1

20.81

23.84

u/l

0.25

293

Dipeptidyl peptidase 4 (DPP-4) inhibitors

202

1.19

0.31

1.0

1.1

38.72

26.84

u/l

0.49

147

Other abnormal products of conception

449

1.10

0.30

1.1

16.54

17.58

u/l

0.09

364

Lichen planus, including avohilmo

371

1.13

0.30

1.1

15.49

26.54

u/l

1.75

277

Metatarsalgia

166

1.21

0.29

1.3

1.2

11.08

19.53

u/l

1.85

129

Single delivery by forceps and vacuum extractor

159

0.84

0.29

1.3

1.2

16.75

19.54

u/l

0.17

131

Oter anti-inflammatory and antirheumatic agents, non-steroids

269

1.11

0.29

1.1

37.87

30.55

u/l

0.24

199

Other benign neoplasms of connective and other soft tissue

176

1.19

0.28

1.2

1.1

14.12

24.50

u/l

1.68

129

Endometriosis of rectovaginal septum and vagina

121

1.24

0.28

1.1

58.78

21.28

u/l

—

Ectopic pregnancy

407

0.88

0.27

1.1

28.35

19.73

u/l

0.36

330

Benign neoplasm: Ascending colon

233

1.16

0.27

1.1

24.44

34.57

u/l

0.82

172

Embedded and impacted teeth

274

0.87

0.27

1.0

1.2

24.13

15.71

u/l

0.43

213

Other noninflammatory disorders of uterus, except cervix

359

1.10

0.27

1.1

26.93

26.81

u/l

0.01

268

Chalazion

172

0.81

0.27

1.0

1.1

106.00

26.34

u/l

—

134

Coxibs

305

1.10

0.27

1.1

1.2

35.10

28.00

u/l

0.20

227

Triptan medication for migraine, min. 3 purchases

119

1001

0.94

0.27

1.2

1.1

20.58

19.03

u/l

0.14

799

Obstructed labour due to maternal pelvic abnormality

364

0.88

0.27

1.2

23.33

21.03

u/l

0.09

288

Dental caries 2 and operation codes, only avohilmo

184

1084

1.05

0.27

1.1

17.97

23.62

u/l

0.69

140

824

Medical treatment for female infertility

346

1.12

0.26

1.2

14.11

15.64

u/l

0.15

287

DVT of lower extremities

366

1.12

0.26

1.2

1.1

32.01

28.62

u/l

0.11

272

Atrophic disorders of skin

262

1.15

0.26

1.0

1.1

25.62

22.52

u/l

0.15

194

Impingement syndrome of shoulder

519

1.10

0.26

1.1

23.17

29.06

u/l

0.43

403

Retinal vascular occlusion

206

1.17

0.26

1.3

1.1

17.38

37.30

u/l

2.10

149

LSIL lesion of the cervix uteri, vagina or vulva

244

1.15

0.25

1.0

1.2

26.59

17.97

u/l

0.37

198

Gestational diabetes (for exclusion)

486

0.92

0.25

1.1

1.2

10.41

16.74

u/l

2.54

394

Parkinson's disease

256

0.86

0.25

1.2

1.1

21.36

32.89

u/l

0.87

190

Non-allergic asthma (mode), excluding more controls

318

1.12

0.24

1.1

18.01

24.66

u/l

0.59

228

Bacterial pneumoniae

701

1.07

0.24

1.1

20.21

23.65

u/l

0.44

527

Abnormal findings on antenatal screening of mother

0.71

0.24

1.2

6.00

21.23

u/l

—

Enteropathic arthropathies

1.32

0.23

1.0

12.40

24.74

u/l

—

Generalized epilepsy, strict definition

1.32

0.23

1.0

1.1

40.80

32.51

u/l

—

Melanocytic naevi of scalp and neck

1.28

0.23

1.2

1.1

22.80

35.68

u/l

—

Other specified disorders of muscle

1.28

0.23

1.4

1.1

21.40

24.59

u/l

—

Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances

1.24

0.23

1.3

1.1

32.00

24.68

u/l

—

Parkinson's disease, strict definition

232

0.86

0.22

1.1

21.07

33.81

u/l

0.86

174

COPD, hospital admissions 1, only main diagnosis

611

1.07

0.22

1.1

22.94

31.04

u/l

1.05

449

Other peripheral vascular diseases

125

1.20

0.22

1.1

11.80

22.98

u/l

1.20

Superficial injury of head

371

1.11

0.22

1.1

40.69

23.39

u/l

0.37

284

Acute appendicitis, no complications

130

1231

1.05

0.22

1.2

1.1

16.91

25.88

u/l

3.00

102

965

Schizophrenia

257

1.13

0.22

1.1

22.54

21.87

u/l

0.02

198

Dysplasia of cervi uteri

376

1.09

0.22

1.1

21.68

16.80

u/l

0.46

300

Malignant neoplasm of base of tongue

0.00

0.21

0.0

1.2

—

54.78

—

Motorcycle rider injured in noncollision transport accidents

1.19

0.21

1.0

1.2

6.22

28.08

u/l

—

Cicatricial alopecia [scarring hair loss]

0.00

0.21

0.0

1.2

—

4.40

—

Marginal zone B-cell lymphoma

0.00

0.21

0.0

1.2

—

39.00

—

Benign neoplasm: Scapula and long bones of upper limb

0.00

0.21

0.0

1.3

—

8.54

—

Mandibular prognathia AND surgery (LeFortI or BSSO or LeFortI AND BSSO), including avohilmo

0.00

0.21

0.0

1.0

—

24.29

—

Right side

0.00

0.21

0.0

1.2

—

36.46

—

Hyperprolactinaemia, drug-induced

0.00

0.21

0.0

1.3

—

25.26

—

Carcinoma in situ of uteri, other/unspecified

0.00

0.21

0.0

1.1

—

9.39

—

Other specified and unspecified disorders of lens

0.00

0.21

0.0

1.2

—

24.00

—

Melanoma in situ of other and unspecified parts of face

0.00

0.21

0.0

1.2

—

32.88

—

Malignant neoplasm of renal pelvis, excluding all cancers (controls excluding all cancers)

0.00

0.21

0.0

1.2

—

24.59

—

Palmar fascial fibromatosis [Dupuytren]

287

1.12

0.20

1.2

1.1

22.04

32.97

u/l

0.93

207

Pregnancy with abortive outcome

175

876

1.04

0.20

1.2

1.1

20.51

21.78

u/l

0.15

135

676

Carcinoma in situ of uteri, other/unspecified

0.00

0.20

0.0

1.1

—

12.34

—

Correction of physiology of bite - very demanding therapy visit

1.23

0.20

1.0

1.1

7.50

27.25

u/l

—

Malignant neoplasm of brain

1.23

0.20

1.3

1.1

39.50

23.97

u/l

—

Orchitis and epididymitis

136

1.18

0.20

1.0

1.1

30.73

41.66

u/l

0.34

105

Benign neoplasm of mouth and pharynx

193

1.14

0.19

1.0

1.1

26.67

26.51

u/l

0.01

140

Glucosamine medication

129

983

1.05

0.18

1.1

32.45

28.11

u/l

0.34

101

745

Redundant prepuce, phimosis and paraphimosis

288

1.11

0.18

1.1

24.89

40.75

u/l

1.00

225

Benign neoplasm of major salivary glands

175

1.14

0.18

1.4

1.1

25.55

29.83

u/l

0.20

128

Infections of genitourinary tract in pregnancy

175

1.14

0.18

1.5

1.1

18.79

18.05

u/l

0.04

137

Visual field defects

147

1.16

0.18

1.2

1.1

129.73

30.03

u/l

0.51

110

Hydrocephalus

119

1.18

0.17

1.1

34.67

30.93

u/l

—

Other/unspecified enthesopathies of lower limb, excluding foot

119

1.18

0.17

1.1

17.88

25.92

u/l

—

Dental caries 1 and operation codes, only avohilmo

325

1.07

0.17

1.1

22.49

23.69

u/l

0.08

256

Other symptoms and signs involving the urinary system

157

1.15

0.17

1.3

1.1

56.55

28.65

u/l

0.33

119

Melanocytic naevi of other and unspecified parts of face

1.22

0.17

1.3

1.1

39.50

16.76

u/l

—

Glaucoma, exfoliation

186

1.13

0.16

1.3

1.1

14.35

34.20

u/l

2.03

136

Cervicobrachial syndrome

485

0.93

0.16

1.1

14.95

24.78

u/l

2.48

375

Other and unspecified effects of external causes

495

0.93

0.16

1.1

51.48

22.19

u/l

0.70

380

Desensitization to allergens

1.16

0.16

1.0

1.1

5.29

21.49

u/l

—

Abnormal involuntary movements

215

1.12

0.16

1.2

1.1

20.52

29.59

u/l

0.70

172

Other degenerative diseases of the nervous system

399

0.93

0.16

1.1

31.18

23.93

u/l

0.41

301

Persistent delusional disorders

120

1.17

0.16

1.1

14.32

23.97

u/l

—

HSIL lesion of the cervix uteri

294

1.09

0.14

1.1

1.2

17.73

17.37

u/l

0.03

243

Other complications of labour and delivery, not elsewhere classified

114

0.84

0.14

1.2

12.20

18.87

u/l

—

Premature rupture of membranes

263

0.92

0.14

1.1

1.2

13.07

17.08

u/l

0.51

216

Acute appendicitis, with complications

382

1.07

0.14

1.1

12.58

27.37

u/l

3.64

295

Benign neoplasm: Cerebral meninges

141

1.14

0.14

1.2

1.1

36.60

21.49

u/l

0.52

Injury of muscle and tendon at shoulder and upper arm level

734

0.95

0.12

1.1

22.53

28.43

u/l

0.38

544

Persons encountering health services in circumstances related to reproduction

126

883

0.97

0.12

1.1

1.2

19.81

23.65

u/l

0.52

104

682

Melanocytic naevi of trunk

181

1.11

0.12

1.4

1.1

17.93

28.17

u/l

0.49

139

Other mental disorders due to brain damage and dysfunction and to physical disease

189

0.90

0.12

1.2

1.1

18.17

34.69

u/l

0.80

142

Provisional assignment of new diseases of uncertain etiology

885

1.04

0.12

1.2

1.1

24.16

22.89

u/l

0.08

682

Acne vulgaris

1.16

0.11

1.6

1.1

8.20

17.90

u/l

—

Subarachnoid haemorrhage

172

1.11

0.11

1.3

1.1

34.27

25.14

u/l

0.28

133

Other and unspecified vascular occlusions

153

1.11

0.11

1.3

1.1

17.25

38.35

u/l

1.51

108

Codes for special purposes

887

1.04

0.11

1.2

1.1

24.16

22.86

u/l

0.08

684

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

239

0.92

0.10

1.2

1.1

20.81

27.46

u/l

0.26

181

Subjective visual disturbances

476

1.05

0.10

1.2

1.1

17.03

26.51

u/l

1.37

363

Specific development disorders of scholastic skills

1.15

0.10

1.0

8.64

16.12

u/l

—

Benign neoplasm of ovary

398

1.06

0.10

1.2

1.1

27.74

20.03

u/l

0.36

304

Other disorders of male genital organs

1.09

0.09

1.0

1.2

16.80

32.12

u/l

—

Care involving use of rehabilitation procedures

138

1277

1.03

0.09

1.2

1.1

24.28

22.55

u/l

0.23

982

Gestational [pregnancy-induced] hypertension

486

1.05

0.09

1.1

1.2

13.31

18.92

u/l

0.89

384

Meralgia paraesthetica

1.04

0.09

1.4

1.2

19.20

23.02

u/l

—

Haemangioma, any site

145

1.10

0.09

1.0

1.1

9.85

25.37

u/l

—

110

Migraine with aura

411

0.95

0.09

1.2

1.1

17.06

20.87

u/l

0.25

327

Burns and corrosions

204

1.08

0.08

1.1

22.87

26.22

u/l

0.20

153

Separation of retinal layers (serosa)

1.05

0.08

1.0

1.1

22.33

24.67

u/l

—

Non-allergic asthma (mode)

338

1.06

0.08

1.1

18.01

24.79

u/l

0.62

237

All dysplastic lesions of the cervix uteri

480

0.96

0.08

1.1

20.51

17.06

u/l

0.26

386

Parkinson's disease, excluding more controls

230

0.93

0.08

1.2

1.1

21.36

24.34

u/l

0.19

169

Generalized epilepsy

1.08

0.08

1.0

1.1

32.86

26.07

u/l

—

Malignant neoplasm of mesothelium and soft tissue

1.04

0.08

1.1

51.24

21.85

u/l

—

Parkinson's disease, strict definition, excluding more controls

211

0.93

0.08

1.1

21.07

25.00

u/l

0.23

157

Other acquired deformities of musculoskeletal system and connective tissue

0.81

0.07

1.2

1.1

44.52

26.83

u/l

—

Aneurysms, operations, SAH

313

1.05

0.07

1.2

1.1

28.22

24.64

u/l

0.17

240

Bacterial pneumonia (organism specified)

842

1.03

0.07

1.1

26.00

25.98

u/l

0.00

628

Radiculopathy

327

0.95

0.07

1.1

19.68

27.59

u/l

0.43

243

Dislocation, sprain and strain of joints and ligaments of knee

130

1233

0.98

0.07

1.1

15.62

24.46

u/l

2.74

108

952

Benign neoplasm: Cerebral meninges

173

0.92

0.06

1.2

1.1

36.60

23.15

u/l

0.46

124

Diabetes mellitus in pregnancy

383

1.03

0.06

1.2

16.92

15.55

u/l

0.13

314

Chronic diseases of tonsils and adenoids

191

1190

1.02

0.06

1.1

15.15

26.53

u/l

5.01

156

919

Arthropod-borne viral fevers and viral haemorrhagic fevers

152

0.92

0.06

1.1

44.22

31.45

u/l

—

111

Ill-defined and unknown causes of mortality

1.11

0.05

1.3

1.1

39.00

33.82

u/l

—

Maternal care for known or suspected malpresentation of fetus

206

1.05

0.05

1.1

1.2

19.11

15.90

u/l

0.16

173

Other appendicitis

149

1.07

0.05

1.3

1.1

7.94

23.46

u/l

4.61

115

Other menopausal disorders

388

1.03

0.04

1.2

1.1

20.19

23.06

u/l

0.15

299

Endometriosis

462

0.98

0.04

1.1

30.97

22.61

u/l

0.53

355

malignant neoplasm of female genital organs

322

0.96

0.04

1.2

1.1

19.00

24.23

u/l

0.37

241

Benign neoplasm of meninges

190

1.05

0.04

1.2

1.1

31.04

22.80

u/l

0.33

137

Ptosis of eyelid

190

1.05

0.04

1.1

24.42

32.42

u/l

0.53

140

Complications predominantly related to the puerperium

557

1.02

0.03

1.1

23.47

20.05

u/l

0.20

442

Other and unspecified visual disturbances

159

0.94

0.03

1.1

26.90

25.87

u/l

—

119

Vascular dementia

108

1.07

0.03

1.1

32.29

38.45

u/l

—

Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk

211

1.04

0.03

1.2

1.1

20.81

20.02

u/l

0.03

152

Maternal care for other conditions predominantly related to pregnancy

385

1.03

0.02

1.1

15.13

17.53

u/l

0.17

316

Later onset COPD

424

0.98

0.02

1.2

1.1

22.97

34.82

u/l

1.22

305

Contraceptive management

653

1.01

0.02

1.2

1.1

14.47

22.09

u/l

1.55

512

Other disorders of eye and adnexa

232

1.03

0.02

1.2

1.1

22.64

21.12

u/l

0.07

177

Melanocytic naevi of other and unspecified parts of face

1.08

0.02

1.3

1.1

39.50

23.05

u/l

—

Single delivery by caesarean section

219

0.98

0.02

1.1

1.2

13.68

22.26

u/l

0.99

177

Spontaneous abortion

110

742

1.01

0.01

1.1

23.03

21.17

u/l

0.19

583

Labour and delivery complicated by fetal stress [distress]

225

0.98

0.01

1.3

1.2

13.55

16.08

u/l

0.23

187

Amiodarone users

154

1.04

0.00

1.1

16.38

38.24

u/l

—

116

Unspecified lump in breast

327

1.01

0.00

1.2

1.1

25.60

21.56

u/l

0.11

249

Bacterial pneumonia, not elsewhere classified

664

1.00

0.00

1.1

19.19

24.18

u/l

0.66

499

Chronic suppurative otitis media, including avohilmo

118

1.02

0.00

1.1

75.58

22.89

u/l

0.45

Benign neoplasm: salivary glands, exclude unknown (D119)

158

1.01

0.00

1.4

1.1

20.91

31.34

u/l

—

117

Abnormalities of forces of labour

202

0.99

0.00

1.1

1.2

7.84

19.04

u/l

3.18

169

Lesion of ulnar nerve

232

0.99

0.00

1.1

21.23

27.10

u/l

0.40

176

Deep endometriosis

165

0.97

0.00

1.1

57.50

20.80

u/l

—

128

Other specified/unspecified hearing loss

114

0.96

0.00

1.3

1.1

30.00

31.26

u/l

—

Benign neoplasm: Parotid gland

138

1.01

0.00

1.4

1.1

18.90

28.60

u/l

—

102

Other puerperal infections

1.04

0.00

1.4

1.1

12.90

18.62

u/l

—

Adverse effects, not elsewhere classified

349

1.00

0.00

1.1

29.24

19.47

u/l

0.45

270

Alcohol withdrawal state with delirium

1.03

0.00

1.2

1.1

24.50

26.33

u/l

—

Chronic suppurative otitis media

104

0.96

0.00

1.1

89.10

22.58

u/l

—

Eustachian salpingitis and obstruction

0.93

0.00

1.1

38.22

18.69

u/l

—

Hypospadias

0.00

0.0

1.0

—

2.74

—

Other congenital malformations of male genital organs

0.00

0.0

1.0

—

4.62

—

Oral leukoplakia and related diseases

0.94

0.00

1.4

1.1

30.00

24.22

u/l

—

Other orthopaedic follow-up care

0.92

0.00

1.7

1.1

29.86

15.36

u/l

—

Other inflammation of vagina/vulva

1.02

0.00

1.0

1.1

17.60

20.32

u/l

—

Other diseases of gallbladder

0.88

0.00

1.2

28.33

25.78

u/l

—

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

Coding

Definition

OMOP mapping QC

Cohort

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

LabWAS