Schistosomiasis [bilharziasis], including avohilmo

AB1_SCHISTOSOMIASIS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 B65
  • Hospital discharge: ICD-10 B65
  • Hospital discharge: ICD-9 120
  • Hospital discharge: ICD-8 120
  • Cause of death: ICD-10 B65
  • Cause of death: ICD-9 120
  • Cause of death: ICD-8 120

3 out of 7 registries used, show all original rules.

137

4. Check minimum number of events

None

137

5. Include endpoints

None

137

6. Filter based on genotype QC (FinnGen only)

124

Control definitions (FinnGen only)

Control exclude
AB1_HELMINTIASES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 124 72 52
Unadjusted period prevalence (%) 0.02 0.03 0.02
Median age at first event (years) 55.07 51.92 59.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
132
Matched controls
1320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B65.3
ICD-10 Finland
Cercarial dermatitis
+∞
118.1
95
*
B65.9
ICD-10 Finland
Schistosomiasis, unspecified
+∞
7.4
7
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
50
3.26
3.83
1.4
1.6
—
—
—
0
0
11
27
4.35
3.48
1.4
1.5
359.00
188.00
u/ml
—
6
14
31
159
2.24
3.46
1.5
1.4
908.57
575.00
titre
—
7
32
7
11
6.65
3.23
1.0
1.2
—
—
—
0
0
9
22
4.31
2.94
2.9
1.8
—
—
—
0
0
40
240
1.96
2.94
1.2
1.3
16.94
25.99
iu/ml
—
7
76
74
543
1.83
2.88
11.4
11.4
0.00
0.00
e9/l
0.71
60
438
10
29
3.64
2.75
1.6
1.4
—
—
—
0
0
82
629
1.80
2.68
7.7
7.0
0.18
0.19
e9/l
0.25
71
564
50
338
1.77
2.48
3.3
3.6
0.00
0.02
estimate
0.50
20
129
25
139
1.99
2.25
1.7
1.4
—
—
—
0
0
79
622
1.67
2.16
7.9
6.7
1.77
2.08
e9/l
1.09
70
561
34
213
1.80
2.14
1.1
1.4
1.16
7.14
u/ml
1.29
14
86
77
607
1.64
2.05
7.7
6.7
0.58
0.57
e9/l
0.15
67
534
53
381
1.65
2.03
7.6
6.7
—
—
—
0
0
77
609
1.63
2.01
7.6
6.7
0.04
0.04
e9/l
0.42
66
533
15
72
2.22
1.95
2.1
2.9
—
—
—
0
0
5
12
4.28
1.84
1.2
1.3
—
—
—
0
0
45
319
1.62
1.79
2.5
2.7
—
—
—
0
0
6
19
3.26
1.68
1.5
2.2
—
—
—
0
0
20
114
1.89
1.68
2.6
2.4
44.40
27.89
u/l
0.56
15
89
123
1135
2.23
1.66
19.5
14.5
28.15
22.37
mg/l
1.09
111
915
23
138
1.81
1.65
6.8
6.8
104.61
104.01
mmol/l
0.30
23
138
67
532
1.53
1.59
6.3
7.6
1.20
1.21
mmol/l
0.70
56
462
89
752
1.56
1.59
5.0
4.3
—
241.31
—
0
16
57
438
1.53
1.57
4.7
4.0
18.03
67.56
e6/l
1.15
42
297
83
693
1.53
1.54
11.5
10.7
3.86
4.01
e9/l
0.25
71
605
61
478
1.51
1.53
12.3
10.6
1.24
1.17
inr
0.51
54
401
103
910
1.60
1.41
4.5
4.4
14.40
14.74
pmol/l
0.86
96
839
7
29
2.49
1.41
1.4
1.6
10.83
11.78
mg/l
—
7
29
20
122
1.75
1.37
2.6
2.2
380.50
390.14
nmol/l
0.10
20
111
28
191
1.59
1.28
2.1
2.5
16.87
13.87
umol/l
0.33
28
176
8
36
2.30
1.26
1.0
1.3
—
—
—
0
0
20
125
1.71
1.26
1.5
1.3
—
—
—
0
0
16
95
1.78
1.20
2.7
3.3
—
—
—
0
0
43
328
1.46
1.18
3.5
4.3
7.39
7.39
ph
0.10
31
223
49
384
1.44
1.17
4.0
3.2
10.19
45.75
e6/l
1.51
39
289
5
20
2.56
1.16
1.2
1.2
2157.20
12520.80
e6/l
—
5
10
5
20
2.56
1.16
1.0
2.6
5.40
4.98
kpa
—
5
20
59
479
1.42
1.16
3.4
3.4
6.08
6.23
ph
0.48
36
266
42
320
1.46
1.16
1.4
1.3
2.25
0.99
u/ml
0.30
11
89
43
330
1.45
1.14
3.8
2.9
0.15
0.38
e6/l
1.35
33
232
116
1071
1.69
1.14
5.8
5.4
1.72
1.88
mu/l
1.17
109
997
19
121
1.67
1.13
1.8
1.8
—
—
—
0
0
26
180
1.55
1.12
4.5
3.1
2.83
2.81
e6/l
0.00
13
87
7
32
2.25
1.10
1.9
1.9
—
—
—
0
0
20
131
1.62
1.07
1.3
1.4
—
—
—
0
0
46
363
1.41
1.04
3.1
3.4
—
—
—
0
0
38
290
1.44
1.03
5.4
4.3
—
—
—
0
0
9
49
1.90
1.01
1.2
1.7
—
—
—
0
0
16
101
1.66
0.99
7.3
5.1
0.50
0.64
%
—
6
28
16
101
1.66
0.99
9.1
5.9
0.00
0.33
%
—
5
27
0
29
0.00
0.99
0.0
1.1
—
—
—
0
0
23
160
1.53
0.97
2.2
2.7
22.73
22.79
%
0.01
23
149
117
1092
1.63
0.97
5.4
4.8
5.82
5.86
mmol/l
0.12
110
1012
25
178
1.50
0.95
2.1
2.5
2.39
2.37
g/l
0.06
25
163
6
28
2.20
0.93
1.2
1.0
1.19
0.65
u/ml
—
6
15
100
1078
0.70
0.91
4.5
4.1
1.26
1.27
mmol/l
0.06
93
1003
70
606
1.33
0.85
4.0
3.6
0.00
0.00
estimate
-0.00
20
135
71
619
1.32
0.81
4.0
3.6
0.00
0.00
estimate
-0.00
19
127
0
27
0.00
0.78
0.0
5.9
—
29.50
—
0
22
5
23
2.22
0.77
2.0
1.2
—
—
—
0
0
5
23
2.22
0.77
1.2
4.6
68.38
59.36
%
—
5
23
5
23
2.22
0.77
1.0
1.7
0.29
0.37
nmol/l
—
5
16
23
169
1.44
0.76
1.4
1.6
—
—
—
0
0
5
25
2.04
0.73
1.0
2.9
7.41
7.42
ph
—
5
25
70
615
1.29
0.73
4.0
3.6
0.00
0.00
estimate
-0.00
20
136
111
1040
1.42
0.73
6.7
5.9
38.49
38.70
mmol/mol
0.11
104
984
45
373
1.31
0.72
10.8
5.8
—
—
—
0
0
62
537
1.29
0.72
3.4
2.8
—
—
estimate
—
0
0
125
1204
1.72
0.72
15.2
11.5
27.11
25.53
u/l
0.56
125
1174
56
479
1.29
0.71
2.3
2.0
—
—
—
0
0
10
61
1.69
0.70
1.6
1.2
—
—
—
0
0
44
369
1.29
0.64
3.5
2.3
—
—
—
0
0
33
266
1.32
0.64
3.3
3.9
1.02
1.02
kg/l
0.27
21
168
22
166
1.39
0.64
2.0
2.1
—
—
—
0
0
15
105
1.48
0.63
8.9
5.5
0.00
0.13
%
—
5
31
5
30
1.69
0.62
2.4
3.2
72.40
60.90
%
—
5
30
22
168
1.37
0.60
1.7
1.9
—
—
—
0
0
120
1149
1.49
0.59
20.5
16.0
139.54
139.76
mmol/l
0.64
120
1123
31
253
1.29
0.55
1.9
1.9
1.05
1.27
mg/l
0.24
22
201
6
38
1.61
0.55
10.3
3.3
32.97
71.31
mg/l
—
6
32
6
38
1.61
0.55
10.3
3.3
16.70
24.45
mg/l
—
6
32
14
100
1.45
0.54
1.6
1.3
—
—
—
0
0
14
100
1.45
0.54
2.4
2.7
0.02
0.17
e6/l
2.73
14
93
15
109
1.42
0.53
8.9
5.4
0.40
0.71
%
—
5
35
9
63
1.46
0.53
2.2
6.0
24.03
24.38
mmol/l
—
9
63
6
40
1.52
0.52
1.3
1.3
—
—
—
0
0
9
65
1.41
0.52
5.1
1.3
—
—
—
0
0
13
93
1.44
0.50
1.5
1.2
25.00
87.27
u/ml
—
5
42
35
294
1.26
0.50
2.5
2.0
2.61
2.88
mg/l
0.33
29
258
7
45
1.59
0.50
1.9
3.9
765.43
4463.05
u/ml
—
7
39
35
295
1.25
0.49
1.5
1.5
1.90
2.42
g/l
1.12
21
185
53
468
1.22
0.48
3.5
3.5
0.00
0.04
estimate
0.68
16
114
19
148
1.33
0.47
1.2
1.6
—
—
—
0
0
7
50
1.42
0.46
1.0
1.2
—
—
—
0
0
19
149
1.32
0.45
1.4
1.2
—
—
—
0
0
33
280
1.24
0.43
6.3
5.7
—
—
—
0
0
34
290
1.23
0.43
2.4
2.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
9
66
1.39
0.39
10.1
8.4
96.04
93.91
%
—
9
66
45
399
1.19
0.38
3.3
3.4
17.80
31.72
ng/l
1.29
27
256
53
477
1.19
0.38
2.2
2.0
89.63
94.87
pmol/l
0.44
31
242
5
36
1.40
0.38
1.0
1.2
—
—
—
0
0
5
36
1.40
0.38
1.2
1.1
—
—
—
0
0
9
69
1.33
0.38
5.1
1.3
—
—
—
0
0
10
72
1.42
0.38
7.6
8.9
22.28
24.66
mmol/l
—
10
72
9
71
1.29
0.37
4.8
1.3
—
—
—
0
0
9
71
1.29
0.37
5.1
1.3
—
—
—
0
0
6
43
1.41
0.35
3.5
3.9
36.77
36.87
°c
—
6
43
20
164
1.26
0.35
1.3
1.5
—
—
—
0
0
27
232
1.21
0.32
1.8
1.8
—
—
—
0
0
55
505
1.15
0.30
2.5
2.0
1.50
1.35
mmol/l
0.45
47
420
7
56
1.26
0.30
6.3
1.3
—
—
—
0
0
7
57
1.24
0.29
2.9
4.0
—
—
—
0
0
39
351
1.16
0.28
7.5
5.3
2.53
1.87
ug/l
0.73
33
314
46
501
0.87
0.27
3.0
3.0
—
—
—
0
0
9
72
1.27
0.26
1.0
1.1
—
—
—
0
0
9
72
1.27
0.26
4.8
1.3
—
—
—
0
0
25
219
1.17
0.24
1.8
1.8
280000417.90
61256978.51
pmol/l
0.34
20
191
5
38
1.33
0.23
8.4
1.5
—
—
—
0
0
5
40
1.26
0.22
3.8
10.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
12.5
—
0.65
—
0
12
0
13
0.00
0.21
0.0
22.0
—
1515.69
—
0
13
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
14.8
—
791.46
—
0
13
0
13
0.00
0.21
0.0
1.0
—
274.13
—
0
8
0
14
0.00
0.20
0.0
3.1
—
1.19
—
0
14
0
14
0.00
0.20
0.0
3.1
—
105.86
—
0
14
0
14
0.00
0.20
0.0
3.1
—
3.99
—
0
14
6
52
1.16
0.19
1.0
3.5
1.42
1.16
%
—
6
52
7
62
1.14
0.17
2.7
1.5
—
—
—
0
0
121
1190
1.20
0.16
15.2
12.6
—
—
—
0
0
7
87
0.79
0.15
1.6
5.0
78.00
78.00
ng/l
—
7
76
36
336
1.10
0.14
3.1
2.9
—
0.00
—
0
5
23
210
1.12
0.13
4.0
3.0
352.88
242.99
ng/l
0.17
16
143
24
220
1.11
0.13
3.5
3.0
0.79
0.79
ug/l
0.01
16
137
13
114
1.16
0.12
1.5
1.1
—
—
—
0
0
13
114
1.16
0.12
7.9
7.2
7.45
7.41
ph
—
7
61
122
1206
1.15
0.10
23.8
18.0
70.92
74.40
umol/l
1.58
122
1191
5
47
1.07
0.09
8.0
1.8
—
—
—
0
0
6
53
1.14
0.09
1.0
3.4
0.50
0.64
%
—
6
53
111
1125
0.92
0.08
5.0
4.9
1.47
1.46
mmol/l
0.02
104
1054
127
1257
1.27
0.08
29.6
22.2
136.02
135.91
g/l
0.03
127
1245
127
1256
1.29
0.08
29.4
22.0
30.09
30.26
pg
0.50
127
1245
127
1256
1.29
0.08
30.1
22.4
40.87
40.59
%
0.34
127
1245
127
1256
1.29
0.08
29.3
22.1
90.41
90.70
fl
0.29
127
1246
34
357
0.94
0.08
3.2
2.9
0.00
0.01
estimate
0.50
17
108
7
80
0.87
0.07
3.3
3.1
7.44
7.41
ph
—
7
68
40
386
1.05
0.06
4.4
3.1
7.63
8.08
mmol/l
0.27
35
326
11
119
0.92
0.04
1.2
1.5
—
—
—
0
0
16
151
1.07
0.03
1.4
1.2
—
—
—
0
0
35
359
0.97
0.02
1.7
1.5
—
—
—
0
0
34
348
0.97
0.02
4.1
3.3
41.10
54.55
mg/l
0.19
23
223
10
96
1.05
0.00
9.9
8.4
—
—
—
0
0
10
104
0.96
0.00
2.2
5.5
0.60
1.75
mmol/l
—
10
87
10
104
0.96
0.00
1.7
1.6
—
—
—
0
0
114
1139
1.01
0.00
5.8
5.6
2.77
2.71
mmol/l
0.27
107
1071
113
1131
0.99
0.00
5.2
4.9
4.65
4.63
mmol/l
0.10
106
1068
35
347
1.01
0.00
5.2
4.0
8.42
9.65
mg/mmol
0.06
22
216
0
6
0.00
0.00
0.0
1.0
—
4.95
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
7
77
0.90
0.00
1.0
1.2
—
—
—
0
0
7
78
0.89
0.00
3.6
3.7
4.72
4.54
pmol/l
—
7
70
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
90.67
—
0
6
0
6
0.00
0.00
0.0
1.0
—
12.88
—
0
6
0
6
0.00
0.00
0.0
1.0
—
160.00
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
1.83
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
100.30
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_SCHISTOSOMIASIS_WIDE – Schistosomiasis [bilharziasis], including avohilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).