Helminthiases

AB1_HELMINTIASES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B65-B83
  • Hospital discharge: ICD-9 12[0-3]
  • Hospital discharge: ICD-8 12[0-9]|13602
  • Cause of death: ICD-10 B65-B83
  • Cause of death: ICD-9 12[0-3]
  • Cause of death: ICD-8 12[0-9]|13602

2 out of 7 registries used, show all original rules.

701

4. Check minimum number of events

None

701

5. Include endpoints

744

6. Filter based on genotype QC (FinnGen only)

648

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF6V3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8913 4944 3842
Only index persons 5959 3558 2401
Unadjusted period prevalence (%)
Whole population 0.13 0.14 0.11
Only index persons 0.12 0.13 0.09
Median age at first event (years)
Whole population 33.97 31.17 37.09
Only index persons 29.01 28.92 29.15

-FinnGen-

Key figures

All Female Male
Number of individuals 648 398 250
Unadjusted period prevalence (%) 0.13 0.14 0.11
Median age at first event (years) 36.75 33.91 41.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
682
Matched controls
6820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B80
ICD-10 Finland
Enterobiasis
193.7
309.5
151
10
12340
ICD-8 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
128.3
119
*
12730
ICD-8 Finland
Other intestinal helminthiasis, Enterobiasis
+∞
32.6
31
*
1252A
ICD-9 Finland
Filarial infection and dracontiasis, Loiasis
+∞
24.1
23
*
B76.9
ICD-10 Finland
Hookworm disease, unspecified
+∞
19.9
19
*
B83.9
ICD-10 Finland
Helminthiasis, unspecified
92.4
16.6
18
*
B70.0
ICD-10 Finland
Diphyllobothriasis
+∞
14.6
14
*
B82.9
ICD-10 Finland
Intestinal parasitism, unspecified
+∞
13.6
13
*
12700
ICD-8 Finland
Other intestinal helminthiasis, Ascariasis
+∞
12.5
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
11.5
108
538
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
10.9
77
340
D01
ICPC
Abdominal pain/cramps general
2.0
9.4
105
558
B83.8
ICD-10 Finland
Other specified helminthiases
+∞
9.4
9
*
12899
ICD-8 Finland
Other and unspecified helminthiasis, Unspecified
+∞
9.4
9
*
B65.3
ICD-10 Finland
Cercarial dermatitis
50.6
8.7
10
*
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.4
8.5
21
49
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
8.4
74
359
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.2
191
1275
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.5
7.9
19
43
N02AX02
ATC
tramadol; systemic, rectal
1.6
7.9
275
2024
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.7
254
1846
A02BC01
ATC
omeprazole; systemic
1.7
7.6
183
1229
12299
ICD-8 Finland
Hydatidosis, Of unspecified site
+∞
7.3
7
*
B82.0
ICD-10 Finland
Intestinal helminthiasis, unspecified
+∞
7.3
7
*
B78.9
ICD-10 Finland
Strongyloidiasis, unspecified
+∞
7.3
7
*
12699
ICD-8 Finland
Ankylostomiasis, Unspecified
+∞
7.3
7
*
12720
ICD-8 Finland
Other intestinal helminthiasis, Trichuriasis
+∞
7.3
7
*
B65.9
ICD-10 Finland
Schistosomiasis, unspecified
+∞
7.3
7
*
12740
ICD-8 Finland
Other intestinal helminthiasis, Other intestinal nematode infection
+∞
7.3
7
*
N77.1*B80
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in pinworm infection
+∞
7.3
7
*
B77.9
ICD-10 Finland
Ascariasis, unspecified
+∞
7.3
7
*
1234A
ICD-9 Finland
Other cestode infection, Diphyllobothriasis, intestinal
+∞
7.3
7
*
R4110
NOMESCO Finland
Physiotherapy
1.6
6.3
179
1246
1274A
ICD-9 Finland
Other intestinal helminthiases, Enterobiasis
+∞
6.3
6
*
B81.4
ICD-10 Finland
Mixed intestinal helminthiases
+∞
6.3
6
*
12320
ICD-8 Finland
Other cestode infection, Taenia saginata infection
+∞
6.3
6
*
B83.0
ICD-10 Finland
Visceral larva migrans
+∞
6.3
6
*
B78.0
ICD-10 Finland
Intestinal strongyloidiasis
+∞
6.3
6
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
6.1
42
183

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
299
1987
1.90
14.60
9.5
6.4
—
—
—
0
0
106
565
2.04
9.42
2.6
2.6
37.81
33.17
u/l
0.28
90
464
381
3038
1.58
7.72
8.8
6.3
10.83
11.29
umol/l
0.54
367
2891
358
2826
1.56
7.49
10.4
6.4
3.12
2.87
%
0.97
335
2653
357
2822
1.56
7.39
10.5
6.5
0.73
0.69
%
0.74
331
2641
357
2826
1.55
7.31
10.5
6.5
8.92
8.71
%
0.64
334
2659
389
3164
1.53
6.86
10.3
6.6
0.21
0.19
e9/l
0.73
349
2763
37
145
2.64
6.72
1.5
1.4
172.77
222.69
u/ml
0.92
24
79
360
2898
1.51
6.54
10.4
6.4
28.67
28.36
%
0.21
340
2760
20
55
3.72
6.51
1.3
2.0
—
—
—
0
0
113
691
1.76
6.51
4.0
3.0
6.21
7.26
umol/l
0.47
94
597
356
2869
1.50
6.37
10.1
6.3
55.71
56.92
%
1.23
337
2737
374
3057
1.49
6.16
9.9
6.3
0.56
0.57
e9/l
0.20
332
2619
262
1993
1.51
6.13
4.0
3.3
31.42
31.24
u/l
0.02
251
1893
374
3068
1.49
5.98
9.9
6.3
0.04
0.04
e9/l
0.54
330
2626
499
4364
1.53
5.68
12.1
7.9
81.03
79.78
u/l
0.23
484
4124
287
2258
1.47
5.54
4.8
4.1
39.53
114.09
e6/l
2.17
197
1560
134
895
1.62
5.51
3.5
2.4
2.45
2.34
g/l
1.38
127
831
378
3138
1.46
5.49
10.0
6.3
1.99
1.96
e9/l
0.06
344
2774
404
3400
1.46
5.44
13.5
9.5
3.85
4.03
e9/l
0.89
360
2943
233
1767
1.48
5.38
8.6
6.1
—
—
—
0
0
211
1569
1.50
5.37
3.0
2.2
2.73
2.86
mg/l
0.39
184
1359
198
1463
1.50
5.16
4.1
3.7
—
0.21
—
0
14
49
251
2.03
4.87
1.6
1.4
—
—
—
0
0
44
218
2.09
4.78
1.6
1.9
—
—
—
0
0
103
669
1.64
4.71
3.8
3.0
1.77
1.83
%
0.16
92
602
147
1038
1.53
4.71
3.4
3.1
0.76
1.00
e6/l
0.90
83
542
324
2673
1.40
4.55
13.6
11.2
0.00
0.00
e9/l
0.81
265
2169
80
492
1.71
4.50
3.2
2.8
10.94
10.33
g/l
0.60
74
457
113
760
1.58
4.48
1.8
1.6
—
—
—
0
0
177
1314
1.47
4.42
2.4
2.1
—
—
—
0
0
33
151
2.25
4.38
1.2
1.3
—
—
—
0
0
12
24
5.07
4.33
3.2
4.0
421.08
826.79
u/ml
1.09
12
24
313
2590
1.39
4.21
9.6
6.5
1.21
1.21
mmol/l
0.20
302
2392
18
62
2.95
4.20
1.4
2.2
—
—
—
0
0
28
122
2.35
4.16
1.7
1.5
122.86
156.50
au/ml
—
7
41
244
1943
1.40
4.10
4.0
3.5
50.73
93.45
e6/l
0.51
187
1476
221
1731
1.41
4.09
6.3
3.9
7.40
7.40
ph
0.11
169
1237
67
406
1.72
3.99
2.5
2.4
37.66
18.92
au/ml
—
7
36
150
1099
1.47
3.97
1.9
1.7
—
—
—
0
0
134
961
1.49
3.95
3.6
3.3
2.32
2.60
e6/l
0.20
66
466
441
3882
1.38
3.95
5.6
4.8
307.00
2372.99
e6/l
—
5
69
78
494
1.65
3.94
3.7
2.9
65.14
70.98
e9/l
0.83
58
371
213
1668
1.40
3.92
3.9
3.4
0.17
0.40
e6/l
3.09
151
1210
103
701
1.55
3.87
1.9
1.6
—
—
—
0
0
392
3392
1.37
3.87
7.1
5.0
6.51
6.58
mmol/l
0.27
377
3179
300
2495
1.36
3.79
7.8
5.0
35.77
35.98
g/l
0.28
289
2352
29
135
2.20
3.72
1.8
1.5
—
—
—
0
0
129
929
1.48
3.72
6.9
3.8
0.81
0.82
mmol/l
0.15
122
885
83
544
1.60
3.67
1.2
1.2
—
—
—
0
0
95
645
1.55
3.61
1.4
1.3
—
—
—
0
0
130
946
1.46
3.55
1.7
1.7
1155.44
1170.35
nmol/l
0.06
108
723
82
543
1.58
3.48
9.3
9.2
—
—
—
0
0
312
2641
1.33
3.40
3.0
2.6
78.42
75.80
nmol/l
0.97
291
2390
44
248
1.83
3.37
1.2
1.2
—
—
—
0
0
302
2547
1.33
3.36
14.8
13.1
1.22
1.22
inr
0.01
252
2114
226
1826
1.36
3.35
3.2
3.1
—
—
—
0
0
33
169
2.00
3.34
1.5
1.4
279.91
298.45
ug/g
0.22
22
97
144
1081
1.42
3.32
4.1
3.9
452.66
350.53
ng/l
0.14
97
813
343
2954
1.32
3.27
4.3
3.1
104.65
108.07
ug/l
0.13
320
2757
68
438
1.61
3.24
5.8
4.0
90.49
76.38
ng/l
0.61
61
394
295
2489
1.33
3.24
2.4
2.1
91.80
95.60
pmol/l
0.74
162
1277
35
186
1.93
3.21
10.6
9.4
—
—
—
0
0
199
1586
1.36
3.20
5.2
4.1
—
—
—
0
0
8
15
5.38
3.20
1.1
1.1
—
—
—
0
0
53
321
1.71
3.19
1.3
1.3
—
—
—
0
0
115
834
1.46
3.19
2.7
2.4
100.99
110.54
ug/g
0.18
93
667
269
2246
1.33
3.16
2.2
2.2
—
—
—
0
0
63
403
1.62
3.09
2.1
1.7
1.10
1.48
g/l
1.24
57
376
50
302
1.71
3.05
1.3
1.5
23.69
23.17
iu/l
0.04
35
251
334
2886
1.31
3.03
11.3
7.1
1.21
1.21
mmol/l
0.20
299
2506
99
709
1.46
2.93
1.7
1.4
—
—
—
0
0
169
1330
1.36
2.92
3.1
2.7
3.81
6.48
e6/l
2.31
154
1204
233
1924
1.32
2.91
3.6
2.4
—
—
—
0
0
222
1823
1.32
2.88
3.5
2.6
75.59
62.77
u/l
0.42
205
1693
26
132
2.01
2.74
1.2
1.6
3.55
3.69
mmol/l
0.25
26
125
37
212
1.79
2.73
2.2
2.8
—
—
—
0
0
8
19
4.25
2.68
4.0
3.2
—
—
—
0
0
173
1385
1.33
2.65
2.0
1.4
2.16
2.36
g/l
0.68
103
841
11
36
3.09
2.57
1.3
1.2
—
—
—
0
0
182
2207
0.76
2.55
3.2
3.1
—
—
—
0
0
72
498
1.50
2.54
1.6
1.5
—
—
—
0
0
23
115
2.03
2.53
1.3
1.7
—
—
—
0
0
13
51
2.58
2.45
1.0
1.2
—
—
—
0
0
28
153
1.87
2.42
1.2
1.6
630.32
468.45
mg/l
0.97
28
146
17
77
2.24
2.39
1.5
1.3
—
—
—
0
0
43
270
1.63
2.32
2.2
2.4
—
—
—
0
0
9
28
3.24
2.31
1.7
1.8
—
—
—
0
0
24
127
1.92
2.28
1.2
1.1
3.25
4.44
u/ml
0.18
13
73
83
607
1.42
2.22
5.6
4.3
1.27
1.88
mmol/l
1.03
76
516
26
144
1.84
2.17
1.6
2.7
—
—
—
0
0
143
1149
1.31
2.11
3.2
3.0
552.51
527.53
mosm/kgh2o
0.64
131
999
85
631
1.40
2.10
5.8
4.2
7.38
7.38
ph
0.24
46
370
486
5177
0.79
2.09
4.4
4.1
1.27
1.26
mmol/l
0.07
452
4790
24
132
1.85
2.06
1.3
1.7
52.28
12.81
e6/l
0.96
18
103
24
134
1.82
1.97
1.3
1.7
39.11
952.06
e6/l
0.57
19
106
7
21
3.36
1.97
1.4
1.1
—
—
—
0
0
44
291
1.55
1.95
3.0
2.3
154.74
5687.42
u/l
2.26
20
119
10
39
2.59
1.94
1.9
1.8
—
—
—
0
0
22
121
1.85
1.90
1.2
1.1
0.60
0.70
u/ml
0.14
12
59
7
22
3.20
1.88
1.0
1.0
—
—
—
0
0
9
34
2.67
1.87
8.4
3.4
0.56
0.97
index
—
9
34
8
28
2.88
1.86
2.0
1.6
91.24
56.66
ug/l
—
8
28
13
59
2.23
1.85
1.0
1.1
—
—
—
0
0
30
183
1.67
1.85
1.2
1.2
—
—
—
0
0
6
17
3.55
1.84
1.3
1.2
—
—
—
0
0
6
17
3.55
1.84
3.2
1.4
—
—
—
0
0
175
1469
1.26
1.82
3.2
2.3
—
—
—
0
0
101
790
1.33
1.81
1.2
1.2
—
—
—
0
0
7
23
3.06
1.80
1.6
1.5
137.43
149.87
nmol/l
—
7
23
420
3869
1.22
1.79
4.1
3.4
45.92
45.61
u/l
0.03
402
3643
26
154
1.72
1.78
5.8
2.9
3.13
1.78
index
0.58
16
87
33
209
1.61
1.77
1.2
1.6
11.68
9.30
u/l
0.44
26
168
16
81
2.00
1.76
1.1
1.2
—
—
—
0
0
99
776
1.32
1.75
2.0
1.8
—
—
—
0
0
161
1345
1.26
1.74
2.9
1.9
1.29
1.22
mg/l
0.11
119
1047
22
126
1.77
1.70
1.3
1.1
1.37
1.74
u/ml
0.14
13
70
57
411
1.42
1.69
1.3
1.2
—
—
—
0
0
25
149
1.70
1.69
1.3
1.2
3.13
2.66
u/ml
0.06
15
85
21
119
1.79
1.68
1.3
2.7
4.82
9.25
umol/l
0.92
13
88
20
112
1.81
1.66
1.2
1.1
—
—
—
0
0
7
25
2.82
1.65
1.7
1.9
—
—
—
0
0
37
246
1.53
1.64
1.2
1.4
169.43
265.26
miu/ml
1.08
14
111
352
3205
1.20
1.63
4.6
4.0
0.02
0.48
estimate
0.49
57
634
5
14
3.59
1.62
2.0
1.4
—
—
—
0
0
13
63
2.08
1.60
3.7
2.8
19.29
22.66
nmol/l
0.58
13
57
15
77
1.97
1.60
1.5
1.3
—
—
—
0
0
18
99
1.84
1.58
1.2
1.1
8.82
6.99
u/ml
—
9
41
170
1445
1.24
1.57
4.5
3.9
1.02
1.02
kg/l
0.62
110
954
65
487
1.37
1.56
2.6
2.5
0.35
0.38
e6/l
0.06
60
462
20
115
1.76
1.54
1.2
1.1
—
—
—
0
0
20
115
1.76
1.54
1.2
1.1
—
—
—
0
0
18
101
1.80
1.50
1.1
1.1
—
—
—
0
0
167
1427
1.23
1.47
3.5
2.8
330.34
338.53
umol/l
0.46
149
1264
519
5430
0.82
1.46
5.2
4.8
1.47
1.47
mmol/l
0.03
485
5059
286
2574
1.19
1.46
4.2
3.5
6.32
6.23
ph
0.64
150
1450
179
1543
1.22
1.44
1.7
1.4
1.39
1.52
u/ml
0.08
40
411
242
2147
1.20
1.44
3.6
3.8
31.94
39.40
ng/l
0.38
163
1497
12
59
2.05
1.44
1.3
1.2
—
—
—
0
0
17
96
1.79
1.40
1.6
1.2
1.33
5.80
u/ml
—
6
45
29
190
1.55
1.39
1.7
2.0
42.31
41.39
nmol/l
0.07
29
182
5
17
2.95
1.36
2.8
2.5
42.16
42.12
g/l
—
5
17
17
97
1.77
1.36
2.0
1.9
—
—
—
0
0
107
880
1.26
1.33
1.5
1.4
386.67
454.85
titre
0.41
24
194
199
1746
1.20
1.33
2.6
2.1
177.88
237.76
u/l
0.57
189
1669
522
5445
0.82
1.33
5.3
4.9
4.58
4.62
mmol/l
0.44
490
5098
19
113
1.70
1.33
1.2
1.0
3.32
5.15
u/ml
0.34
13
56
221
1958
1.19
1.32
3.9
3.5
7.64
7.74
mmol/l
0.10
191
1669
39
276
1.44
1.32
1.5
2.0
6.86
7.20
iu/ml
—
7
61
6
24
2.51
1.30
2.7
1.7
—
—
—
0
0
26
170
1.55
1.27
1.3
1.3
—
—
—
0
0
345
3181
1.17
1.27
4.6
3.9
0.00
7.25
estimate
1.07
58
677
342
3152
1.17
1.26
4.5
3.9
0.00
0.00
estimate
-0.00
60
664
167
1909
0.83
1.25
3.7
3.5
—
0.80
—
0
5
8
37
2.18
1.21
2.9
2.4
309.63
179.77
e6/l
—
8
30
13
71
1.85
1.20
3.0
2.2
—
—
—
0
0
13
71
1.85
1.20
1.5
1.7
29.24
28.39
ng/l
0.04
13
71
104
865
1.24
1.19
2.3
1.9
—
—
—
0
0
6
26
2.32
1.19
1.0
1.2
105.53
173.87
iu/ml
—
6
26
587
5678
1.24
1.18
24.4
17.7
139.50
139.63
mmol/l
0.63
581
5571
411
3856
1.17
1.17
4.4
4.0
—
0.13
—
0
8
65
511
1.30
1.17
6.3
5.1
0.80
0.96
%
0.22
30
167
11
57
1.95
1.17
1.2
1.1
—
—
—
0
0
10
50
2.01
1.17
1.3
2.5
36.52
43.63
%
—
10
50
586
5669
1.24
1.16
22.1
15.1
21.94
24.00
mg/l
1.01
502
4622
62
485
1.31
1.16
6.3
4.9
0.59
0.55
%
0.06
29
151
23
151
1.54
1.13
3.3
3.3
1.25
2.15
ratio
1.11
17
87
587
5687
1.23
1.10
24.8
17.8
3.94
3.96
mmol/l
1.37
578
5563
5
21
2.39
1.09
2.4
3.5
—
—
—
0
0
104
874
1.22
1.09
3.1
3.1
0.69
0.78
ug/l
0.65
68
554
15
89
1.70
1.08
2.6
1.6
—
—
—
0
0
15
89
1.70
1.08
2.6
1.6
—
—
—
0
0
15
89
1.70
1.08
2.6
1.6
—
—
—
0
0
15
89
1.70
1.08
2.6
1.6
—
—
—
0
0
7
33
2.13
1.05
1.1
1.2
—
—
—
0
0
55
431
1.30
1.03
2.3
2.4
10.21
7.27
ug/l
0.42
45
383
5
22
2.28
1.03
1.8
3.8
—
—
—
0
0
18
114
1.59
1.03
2.3
3.4
—
—
—
0
0
14
83
1.70
1.02
2.5
1.7
—
—
—
0
0
16
99
1.63
1.00
1.4
1.4
—
—
—
0
0
156
1374
1.18
0.99
6.0
4.9
—
—
—
0
0
20
132
1.53
0.98
2.3
2.3
129.57
127.79
g/l
0.13
14
105
90
755
1.22
0.97
1.6
1.6
—
—
—
0
0
77
638
1.23
0.94
10.7
8.4
7.42
7.42
ph
0.13
34
356
134
1172
1.18
0.93
1.7
1.7
50909569.83
30091624.20
pmol/l
0.16
110
987
194
1747
1.15
0.93
4.1
3.4
34.41
57.20
mg/l
1.36
127
1121
26
184
1.43
0.93
2.8
4.1
8.83
8.42
kpa
0.52
26
179
60
484
1.26
0.92
6.0
5.2
0.00
0.13
%
3.75
25
138
164
1461
1.16
0.91
5.5
5.1
1.76
2.37
ug/l
1.24
149
1321
11
63
1.76
0.90
14.5
3.7
10.57
10.98
%
0.12
11
63
51
405
1.28
0.89
4.7
3.9
7.41
7.41
ph
0.48
45
336
44
343
1.30
0.88
12.5
10.5
23.64
24.31
mmol/l
0.86
44
336
10
56
1.80
0.88
1.3
1.2
—
—
—
0
0
35
265
1.34
0.86
1.8
1.9
—
—
—
0
0
8
45
1.79
0.84
1.3
1.1
—
—
—
0
0
295
2749
1.13
0.84
3.8
2.8
—
—
estimate
—
0
0
196
1780
1.14
0.83
4.8
4.1
6.20
10.61
mg/mmol
1.24
124
1097
12
73
1.66
0.82
1.2
1.3
—
—
—
0
0
14
89
1.59
0.81
1.1
1.0
0.07
0.45
u/ml
—
6
32
24
173
1.40
0.80
2.2
1.9
5.60
4.57
iu/l
0.15
12
69
45
560
0.79
0.79
1.2
1.4
—
—
—
0
0
75
633
1.21
0.79
10.3
8.4
0.44
0.89
mmol/l
0.41
65
533
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
66
551
1.22
0.77
2.7
2.1
0.33
0.03
estimate
—
9
120
9
53
1.71
0.75
1.9
2.3
1033.22
1234.69
e6/l
—
9
45
470
4521
1.13
0.75
5.3
4.3
14.81
14.71
pmol/l
0.40
439
4149
5
24
2.09
0.74
2.4
3.2
—
—
—
0
0
86
741
1.18
0.73
1.3
1.3
—
—
—
0
0
54
445
1.23
0.72
1.2
1.3
104.95
132.44
u/ml
0.30
20
176
31
238
1.32
0.72
1.6
1.6
53.85
60.75
ug/l
0.48
26
206
502
4853
1.13
0.72
26.2
18.9
13.72
13.56
%
1.60
497
4810
9
57
1.59
0.71
1.4
1.3
—
—
—
0
0
20
143
1.41
0.71
1.6
1.6
5347.00
15432.16
e6/l
1.26
14
105
9
58
1.56
0.70
1.6
1.3
0.33
0.35
g/l
—
9
45
9
58
1.56
0.70
1.4
1.3
2.46
2.75
g/l
—
9
45
9
58
1.56
0.70
1.4
1.3
6.63
6.29
g/l
—
9
46
9
146
0.61
0.70
1.1
1.1
—
—
—
0
0
538
5521
0.88
0.68
6.0
5.6
2.64
2.71
mmol/l
1.11
504
5149
5
28
1.79
0.66
1.2
1.1
—
—
—
0
0
10
62
1.62
0.65
6.6
4.6
—
—
—
0
0
12
79
1.53
0.63
1.2
1.3
275.17
280.56
mosm/kgh2o
0.38
12
61
190
1753
1.12
0.62
4.3
4.0
0.00
0.01
estimate
0.96
56
627
6
104
0.57
0.62
1.3
1.4
22.77
20.98
u/l
—
6
88
8
49
1.64
0.62
1.9
2.6
—
—
—
0
0
5
30
1.67
0.61
1.4
2.0
—
—
—
0
0
56
474
1.20
0.60
3.3
2.3
6.31
6.12
ph
0.90
34
317
26
201
1.31
0.59
4.8
6.9
1.21
1.39
mg/l
0.96
26
182
11
72
1.54
0.59
1.5
3.0
—
—
—
0
0
8
53
1.52
0.58
1.0
1.3
1494.88
2124.21
e6/l
—
8
33
0
23
0.00
0.58
0.0
3.7
—
32.96
—
0
17
6
37
1.63
0.55
2.3
2.3
334.67
573.74
e6/l
—
6
27
12
82
1.47
0.54
1.2
1.1
—
—
—
0
0
9
62
1.46
0.53
1.7
1.3
—
—
—
0
0
604
5939
1.15
0.53
26.7
19.4
74.85
74.80
umol/l
0.01
598
5871
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
26
206
1.27
0.51
1.3
1.3
—
—
—
0
0
58
501
1.17
0.51
7.3
5.5
0.07
0.18
%
0.58
22
128
24
189
1.28
0.50
1.7
1.6
—
—
—
0
0
178
1657
1.10
0.50
3.8
3.4
1358.13
1342.73
ng/l
0.02
154
1411
83
740
1.14
0.49
2.8
2.9
3.89
5.22
e9/l
1.57
68
654
15
110
1.37
0.49
2.1
1.7
—
—
—
0
0
23
181
1.28
0.48
1.7
1.5
1.32
1.30
mm
0.12
17
138
7
46
1.53
0.48
1.0
1.1
86.86
37.10
mg/l
—
7
35
7
46
1.53
0.48
1.0
1.3
—
—
—
0
0
29
237
1.23
0.46
1.5
1.6
13.40
6.60
u/ml
—
6
51
15
112
1.35
0.45
3.3
3.0
1.81
2.78
mmol/l
—
8
75
24
193
1.25
0.44
3.2
2.6
—
—
—
0
0
31
257
1.22
0.44
1.7
2.0
—
—
—
0
0
46
399
1.16
0.41
1.5
1.6
818.19
937.85
mu/l
0.44
36
346
23
186
1.24
0.41
1.7
1.5
—
—
—
0
0
35
297
1.19
0.40
5.1
3.8
—
—
—
0
0
0
18
0.00
0.40
0.0
2.1
—
16.52
—
0
18
13
97
1.35
0.39
1.5
1.6
—
—
—
0
0
164
1745
0.92
0.39
3.7
3.4
0.02
0.05
estimate
0.29
50
537
33
280
1.19
0.38
1.5
1.5
0.25
0.32
mg/l
0.24
12
120
5
36
1.39
0.38
1.0
1.2
0.56
0.50
ratio
—
5
19
5
37
1.35
0.37
1.2
1.5
176.08
158.80
pmol/l
—
5
37
10
72
1.39
0.37
3.2
2.4
—
—
—
0
0
539
5295
1.09
0.36
6.5
5.3
1.86
1.90
mu/l
0.43
507
4915
5
77
0.65
0.36
1.0
1.1
—
—
—
0
0
58
519
1.13
0.35
6.2
3.9
7.32
7.35
ph
0.35
46
383
6
44
1.37
0.34
1.3
2.0
9.15
6.08
mmol/l
—
6
32
246
2358
1.07
0.34
2.0
1.9
1.31
1.34
mmol/l
0.29
213
2008
25
296
0.84
0.33
1.0
1.1
—
—
—
0
0
189
1797
1.07
0.33
1.7
1.5
—
—
—
0
0
41
361
1.14
0.32
3.4
2.4
—
—
—
0
0
7
53
1.32
0.31
1.1
1.5
—
—
—
0
0
175
1665
1.07
0.30
1.8
1.7
18.05
20.46
nmol/l
1.94
156
1408
43
482
0.88
0.30
4.6
4.0
—
—
—
0
0
8
107
0.74
0.29
1.4
3.1
6.14
8.26
pmol/l
—
8
107
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
33
289
1.15
0.28
3.1
2.1
0.00
0.01
estimate
—
8
92
14
114
1.23
0.25
3.4
2.9
90.32
89.27
%
0.35
14
108
61
561
1.10
0.25
5.1
4.2
5.08
29.71
ug/l
1.03
47
462
18
211
0.85
0.23
1.3
1.1
1.53
1.55
g/l
0.07
18
211
5
40
1.25
0.22
2.4
3.2
272.80
16.58
mg/l
—
5
28
595
5896
1.07
0.22
16.6
11.6
25.57
25.78
u/l
0.12
585
5727
110
1044
1.06
0.22
1.4
1.3
1.12
12.78
u/ml
6.32
31
400
5
42
1.19
0.21
2.2
3.5
714.60
1126.21
mg
—
5
42
0
11
0.00
0.21
0.0
1.0
—
0.02
—
0
11
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
8
105
0.76
0.21
6.8
3.6
12.63
24.76
u/ml
—
8
105
17
198
0.85
0.21
1.1
1.1
0.68
0.67
ratio
—
7
26
33
297
1.12
0.20
1.9
2.1
—
—
—
0
0
119
1135
1.06
0.20
3.9
2.6
2.44
2.45
mmol/l
0.17
112
1022
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
32
288
1.12
0.20
1.7
1.7
—
—
—
0
0
6
49
1.23
0.20
1.2
1.3
—
—
—
0
0
19
218
0.87
0.19
1.6
1.2
0.85
0.90
g/l
0.46
19
218
119
1137
1.06
0.19
1.5
1.3
11.64
32.51
iu/ml
7.34
37
329
6
51
1.18
0.19
1.0
1.7
—
—
—
0
0
21
185
1.14
0.18
1.2
1.2
—
—
—
0
0
5
70
0.71
0.16
2.0
2.6
4.12
4.03
mmol/l
—
5
70
5
70
0.71
0.16
2.0
2.6
1.18
1.20
mmol/l
—
5
70
5
70
0.71
0.16
2.0
2.6
104.80
106.14
mmol/l
—
5
70
246
2402
1.04
0.16
4.3
3.8
0.04
0.02
estimate
0.24
47
558
8
71
1.13
0.16
1.6
2.0
31.37
32.37
pg
—
8
71
51
479
1.07
0.14
1.4
1.4
—
—
—
0
0
7
89
0.78
0.14
1.4
1.6
—
—
—
0
0
45
479
0.94
0.13
2.1
1.8
3.48
3.40
mmol/l
0.19
31
354
204
1993
1.03
0.13
4.9
3.2
2.35
2.36
mmol/l
0.26
191
1814
11
94
1.17
0.13
1.2
1.2
—
—
—
0
0
614
6167
0.96
0.10
32.9
23.2
6.62
6.77
e9/l
0.60
607
6033
614
6166
0.96
0.10
32.9
23.1
4.44
4.48
e12/l
1.18
607
6035
34
321
1.06
0.09
2.0
2.0
—
—
—
0
0
6
56
1.07
0.08
1.0
1.0
—
—
—
0
0
614
6163
0.96
0.08
32.9
23.2
251.36
252.92
e9/l
0.22
608
6050
34
322
1.06
0.08
1.9
2.0
—
—
—
0
0
5
62
0.81
0.08
2.2
2.2
—
—
—
0
0
513
5159
0.98
0.07
6.7
6.1
39.00
38.87
mmol/mol
0.12
477
4857
17
184
0.92
0.07
3.2
2.1
9.24
10.29
g/l
0.67
17
167
31
294
1.06
0.07
3.2
3.6
1.02
1.02
ratio
0.01
25
277
584
5818
1.03
0.06
17.3
13.5
—
—
—
0
0
34
325
1.05
0.06
1.9
2.0
—
—
—
0
0
530
5321
0.98
0.05
5.2
4.9
5.91
5.87
mmol/l
0.20
496
4899
23
218
1.06
0.05
5.6
4.8
195.09
365.61
mg/l
1.27
11
99
59
603
0.98
0.03
2.2
1.5
—
—
—
0
0
16
167
0.96
0.01
1.5
1.4
—
—
—
0
0
18
187
0.96
0.01
4.9
4.2
1.29
1.31
mmol/l
0.04
18
181
12
125
0.96
0.00
2.5
4.1
29.97
25.56
mg/l
—
6
84
14
143
0.98
0.00
3.0
4.7
—
—
—
0
0
10
98
1.02
0.00
6.1
3.5
3.60
4.18
e9/l
—
10
98
32
323
0.99
0.00
2.0
1.9
—
—
—
0
0
14
142
0.99
0.00
4.6
3.0
52.31
57.86
%
0.99
14
142
26
262
0.99
0.00
1.1
1.1
—
—
—
0
0
10
99
1.01
0.00
1.2
1.1
—
—
—
0
0
67
671
1.00
0.00
2.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
3.7
—
6.44
—
0
8
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.3
—
0.17
—
0
6
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.5
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
230.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
77.43
—
0
7

Mortality – FinRegistry

Association

Association between endpoint AB1_HELMINTIASES and mortality.

Females

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 1.881 [1.47, 2.4] < 0.001
Birth year 0.992 [0.98, 1.0] 0.076

During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 2014 females with AB1_HELMINTIASES died.

Males

Parameter HR [95% CI] p-value
AB1_HELMINTIASES 2.493 [2.0, 3.1] < 0.001
Birth year 0.98 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 200 out of 1494 males with AB1_HELMINTIASES died.

Mortality risk

Mortality risk for people of age

years, who have AB1_HELMINTIASES.

N-year risk Females Males
1 0.112% 0.394%
5 0.95% 2.228%
10 2.608% 5.756%
15 4.979% 11.009%
20 8.444% 18.296%

Relationships between endpoints

Index endpoint: AB1_HELMINTIASES – Helminthiases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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