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Other helminthiases

AB1_HELMINTHIASES_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B83
  • Hospital discharge: ICD-9 128
  • Hospital discharge: ICD-8 1289
  • Cause of death: ICD-10 B83
  • Cause of death: ICD-9 128
  • Cause of death: ICD-8 1289

2 out of 7 registries used, show all original rules.

51

4. Check minimum number of events

None

51

5. Include endpoints

None

51

6. Filter based on genotype QC (FinnGen only)

49

Control definitions (FinnGen only)

Control exclude
AB1_HELMINTIASES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 419 211 208
Only index persons 309 162 147
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 41.18 38.38
Only index persons 34.17 35.74 32.44

-FinnGen-

Key figures

All Female Male
Number of individuals 49 31 18
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 50.84 47.80 56.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
51
Matched controls
510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B83.9
ICD-10 Finland
Helminthiasis, unspecified
+∞
18.9
17
*
12899
ICD-8 Finland
Other and unspecified helminthiasis, Unspecified
+∞
9.7
9
*
B83.8
ICD-10 Finland
Other specified helminthiases
+∞
8.6
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
59
3.82
4.41
2.5
1.8
66.74
194.24
ug/g
0.84
12
44
8
10
9.23
4.23
1.4
1.3
—
—
—
0
0
7
8
9.90
3.90
1.4
1.4
—
—
—
0
0
12
39
3.70
3.03
4.2
6.1
0.20
0.50
%
—
5
16
36
231
2.90
3.02
13.7
7.4
0.49
0.57
e9/l
1.72
31
205
36
232
2.88
2.97
13.8
7.4
0.04
0.04
e9/l
0.67
31
205
14
56
3.07
2.82
1.3
1.4
—
—
—
0
0
21
108
2.61
2.66
1.8
1.3
0.48
0.88
u/ml
—
8
22
20
101
2.61
2.62
2.6
1.4
2.08
2.50
g/l
0.61
13
61
31
198
2.44
2.42
17.1
11.5
0.00
0.00
e9/l
-0.00
24
165
25
153
2.24
2.06
11.4
6.6
—
—
—
0
0
13
63
2.43
1.78
1.4
1.3
—
—
—
0
0
22
136
2.09
1.70
5.0
5.0
7.39
7.40
ph
0.18
14
104
5
14
3.84
1.65
1.0
3.4
60.30
62.16
%
—
5
14
6
22
2.95
1.48
1.2
1.3
—
—
—
0
0
5
16
3.34
1.47
1.2
1.2
—
—
—
0
0
9
43
2.32
1.39
1.0
1.2
—
—
—
0
0
16
95
2.00
1.34
10.0
6.6
—
—
—
0
0
5
19
2.80
1.24
1.6
1.7
—
—
—
0
0
11
61
2.02
1.08
3.8
8.1
104.36
104.59
mmol/l
0.07
11
61
8
43
2.02
0.93
2.3
1.7
—
—
—
0
0
10
158
0.54
0.90
5.5
3.6
—
—
—
0
0
10
58
1.90
0.87
1.3
1.6
—
—
—
0
0
33
269
1.64
0.86
4.2
5.2
6.35
6.62
mmol/l
0.44
33
256
22
164
1.60
0.82
3.9
3.1
—
—
—
0
0
24
185
1.56
0.77
2.6
2.1
—
—
—
0
0
12
78
1.70
0.73
1.8
1.7
—
—
—
0
0
5
26
2.02
0.73
1.2
1.1
—
—
—
0
0
23
178
1.53
0.71
4.7
4.9
160.02
44.09
e6/l
0.39
18
124
5
27
1.94
0.70
1.8
4.9
23.72
24.57
mmol/l
—
5
27
8
51
1.67
0.64
2.9
1.8
—
—
—
0
0
38
333
1.55
0.62
16.7
8.5
79.32
76.59
u/l
0.19
38
318
29
242
1.46
0.59
5.5
4.3
0.00
0.00
estimate
—
5
46
6
36
1.75
0.59
1.8
2.8
4.67
4.59
kpa
—
6
36
6
37
1.70
0.58
1.0
10.9
—
—
—
0
0
18
138
1.47
0.56
4.1
3.5
0.01
0.31
e6/l
1.68
13
99
14
103
1.50
0.52
2.0
1.9
—
—
—
0
0
7
48
1.53
0.49
1.4
1.9
—
—
—
0
0
17
133
1.42
0.47
5.5
4.0
0.00
0.00
estimate
—
5
43
17
134
1.40
0.45
4.3
3.3
—
—
estimate
—
0
0
5
31
1.68
0.44
1.0
10.5
0.96
1.08
mmol/l
—
5
31
5
32
1.62
0.43
1.4
6.3
7.12
9.67
mmol/l
—
5
32
8
59
1.42
0.43
3.9
4.1
4.15
4.40
e9/l
—
8
53
5
33
1.57
0.42
1.4
1.3
—
—
—
0
0
19
154
1.37
0.42
2.6
2.4
—
—
—
0
0
18
145
1.37
0.41
15.7
7.2
—
—
—
0
0
42
442
0.72
0.40
16.6
13.0
—
—
—
0
0
6
41
1.52
0.38
1.2
1.5
—
—
—
0
0
45
466
0.71
0.36
39.9
24.4
91.20
91.26
fl
0.03
45
460
45
466
0.71
0.36
40.1
24.5
242.09
254.15
e9/l
0.53
45
457
45
466
0.71
0.36
40.3
24.6
133.42
134.17
g/l
0.15
45
460
45
466
0.71
0.36
40.2
24.4
5.99
6.73
e9/l
1.96
45
454
45
466
0.71
0.36
40.0
25.0
39.36
40.10
%
0.32
45
460
45
466
0.71
0.36
40.1
24.4
4.39
4.44
e12/l
0.30
45
455
45
466
0.71
0.36
40.0
24.3
30.34
30.34
pg
0.01
45
460
6
46
1.34
0.34
1.8
3.8
5.58
5.77
kpa
—
6
46
6
46
1.34
0.34
2.2
2.0
—
0.00
estimate
—
0
7
23
198
1.29
0.33
5.3
3.9
6.27
6.23
ph
0.06
11
109
23
201
1.26
0.28
2.2
2.2
106.92
97.24
pmol/l
0.37
12
100
33
301
1.27
0.28
6.6
5.3
—
104.63
—
0
8
9
74
1.26
0.27
2.2
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
6
47
1.31
0.21
1.5
3.7
0.65
2.40
mmol/l
—
6
38
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
12
101
1.25
0.18
4.7
4.1
1.02
1.02
kg/l
—
6
71
23
209
1.18
0.17
6.4
6.2
1.22
1.22
mmol/l
0.13
23
191
42
431
0.86
0.16
27.1
16.2
20.37
23.29
mg/l
0.27
36
363
17
156
1.13
0.09
2.8
3.3
—
—
—
0
0
45
455
0.91
0.09
30.6
20.4
72.53
75.64
umol/l
0.54
45
448
26
247
1.11
0.08
7.2
6.5
12.69
10.65
umol/l
0.44
26
236
13
137
0.93
0.02
6.5
3.7
0.20
0.00
estimate
—
5
39
14
134
1.06
0.01
4.5
4.3
—
—
—
0
0
14
134
1.06
0.01
1.8
1.4
—
—
—
0
0
22
214
1.05
0.00
3.5
2.7
—
—
estimate
—
0
0
10
105
0.94
0.00
4.0
5.0
1.95
2.27
ug/l
—
10
97
5
54
0.92
0.00
1.6
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
44
436
1.07
-0.00
26.5
18.4
3.83
3.94
mmol/l
2.36
44
428
0
5
0.00
-0.00
0.0
1.2
—
32.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
1.20
—
0
9
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
6
58
1.04
-0.00
3.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
7.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
110.33
—
0
6
44
436
1.07
-0.00
26.1
18.1
140.02
139.76
mmol/l
0.36
44
428
0
5
0.00
-0.00
0.0
3.8
—
87.62
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
50
1.00
-0.00
1.6
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
0.67
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
109.22
—
0
9
0
9
0.00
-0.00
0.0
1.4
—
3.94
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_HELMINTHIASES_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_HELMINTHIASES_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_HELMINTHIASES_NOS – Other helminthiases

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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