lens disease: A disease involving the lens of camera-type eye. [database_cross_reference: MONDO:DesignPattern]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
685 |
4. Check minimum number of eventsNone |
685 |
5. Include endpointsNone |
685 |
6. Filter based on genotype QC (FinnGen only) |
627 |
Control definitions (FinnGen only)
- Control exclude
- H7_LENS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- H27
- Name in latin
- Dislocatio lentis
Dislocation of lens
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5172 | 2808 | 2333 |
| Only index persons | 4530 | 2530 | 2000 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.07 |
| Only index persons | 0.09 | 0.09 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 75.35 | 79.10 | 70.85 |
| Only index persons | 75.57 | 79.29 | 70.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 627 | 295 | 332 |
| Unadjusted period prevalence (%) | 0.13 | 0.10 | 0.15 |
| Median age at first event (years) | 74.98 | 77.39 | 72.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 641
- Matched controls
- 6410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
21.5
315.0
509
974
CJB10
NOMESCO Finland
Laser discission of secondary cataract
216.7
307.7
174
11
H25.1
ICD-10 Finland
Senile nuclear cataract
87.9
307.7
365
95
H27.1
ICD-10 Finland
Dislocation of lens
+∞
307.7
605
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
262.5
307.7
459
61
Z96.1
ICD-10 Finland
Presence of intraocular lens
194.4
307.7
493
108
S01ED51
ATC
timolol, combinations; ophthalmic
28.9
307.7
297
186
WX140
NOMESCO Finland
Parabulbar anesthesy
95.8
307.7
320
66
H25.8
ICD-10 Finland
Other senile cataract
193.8
305.4
149
10
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
118.9
287.8
147
16
WX100
NOMESCO Finland
Conjunctival surface anesthesia
57.5
255.3
147
33
H26.4
ICD-10 Finland
After-cataract
339.0
198.0
191
8
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
35.5
190.6
124
43
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
50.1
190.0
112
27
S01BC05
ATC
ketorolac; ophthalmic
52.9
189.1
110
25
H33.0
ICD-10 Finland
Retinal detachment with retinal break
42.7
188.8
116
33
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.2
168.6
199
228
S01EC01
ATC
acetazolamide; systemic
36.8
156.8
100
32
S01EA05
ATC
brimonidine; ophthalmic
30.0
155.2
106
42
S01EE01
ATC
latanoprost; ophthalmic
12.8
152.7
169
175
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
381.1
151.7
147
5
114
Kela drug reimbursment
Glaucoma
10.0
144.1
198
274
XCH00
NOMESCO Finland
Eye pressure measurement
20.7
128.5
102
58
S01ED01
ATC
timolol; ophthalmic
16.7
127.7
114
82
CKD60
NOMESCO Finland
Anterior vitrectomy
673.5
117.0
112
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
13.4
116.7
119
107
CKD40
NOMESCO Finland
Endophotocoagulation of retina
53.3
116.2
67
14
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
651.7
113.7
109
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
436.5
113.2
110
*
S01EC04
ATC
brinzolamide; ophthalmic
15.1
112.0
105
82
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
8.3
93.0
140
210
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
42.0
88.8
54
14
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
36.8
85.6
54
16
H25.0
ICD-10 Finland
Senile incipient cataract
18.2
84.3
70
43
XCK00
NOMESCO Finland
Perimetry
9.4
81.7
106
132
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
46.0
79.0
47
11
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
10.7
78.2
91
98
S01EC54
ATC
brinzolamide, combinations; ophthalmic
33.8
77.4
50
16
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
14.9
77.0
71
53
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
+∞
76.6
72
*
XCK10
NOMESCO Finland
Photography of fundus of eye
6.7
76.1
140
258
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.4
75.2
396
1713
H40.0
ICD-10 Finland
Glaucoma suspect
7.2
72.5
121
201
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
388.1
71.1
70
*
ZXA00
NOMESCO Finland
Right side
4.3
70.6
274
943
S01EE05
ATC
tafluprost; ophthalmic
10.7
68.9
79
83
H43.1
ICD-10 Finland
Vitreous haemorrhage
16.5
64.7
56
37
ZXA05
NOMESCO Finland
Left side
4.2
64.5
247
833
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.7
64.1
186
509
S01EC03
ATC
dorzolamide; ophthalmic
18.0
57.1
47
28
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
13.6
57.0
55
44
S01BC03
ATC
diclofenac; ophthalmic
15.9
56.8
50
34
WX002
NOMESCO Finland
Sedation and analgesia
4.1
54.8
197
626
S01EA03
ATC
apraclonidine; ophthalmic
74.7
54.2
61
9
WX142
NOMESCO Finland
Sub-tenon anesthesy
96.2
48.6
53
6
CJF20
NOMESCO Finland
Removal of artificial lens
+∞
48.6
46
*
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
258.9
47.7
48
*
H27.0
ICD-10 Finland
Aphakia
+∞
46.4
44
*
ZXA10
NOMESCO Finland
Bilateral
4.3
45.1
140
395
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
44.3
42
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
9.3
43.2
54
63
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
6.9
42.3
69
110
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
9.1
40.5
51
60
H26.2
ICD-10 Finland
Complicated cataract
+∞
40.0
38
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
6.7
39.0
65
106
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
+∞
37.9
36
*
H26.02
ICD-10 Finland
Presenil cataract
388.9
37.4
37
*
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
377.6
36.4
36
*
S01EX03, ,
ATC
9.5
35.5
43
48
S01AX11
ATC
[U] ofloxacin
7.3
35.3
54
80
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
190.4
35.1
36
*
H40.9
ICD-10 Finland
Glaucoma, unspecified
11.2
33.4
36
34
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
344.0
33.2
33
*
TCG10
NOMESCO Finland
Removal of sutures from cornea
+∞
32.6
31
*
CS494
NOMESCO Finland
Other visual field testing
9.8
32.1
38
41
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
6.9
32.0
51
79
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
+∞
31.5
30
*
S01EE03
ATC
bimatoprost; ophthalmic
9.0
30.8
39
46
S01BA04
ATC
prednisolone; ophthalmic
8.7
29.4
38
46
S01BA01
ATC
dexamethasone; ophthalmic
7.1
29.2
45
67
S01EE04
ATC
travoprost; ophthalmic
9.0
28.6
36
42
WX199
NOMESCO Finland
Other local analgesia
8.5
28.0
37
46
Q87.4
ICD-10 Finland
Marfan syndrome
293.7
28.0
28
*
ZXD20
NOMESCO Finland
Day surgery
3.6
27.1
99
308
H35.36
ICD-10 Finland
Macular cyst
43.4
27.0
33
8
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
+∞
26.2
25
*
3793B
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[DISLOCATIO LENTIS]
+∞
26.2
25
*
CHC05
NOMESCO Finland
Iridotomy
23.0
25.9
37
17
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
271.0
25.9
26
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
93.9
24.8
27
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
58.4
24.2
28
5
H53.9
ICD-10 Finland
Visual disturbance, unspecified
6.0
24.1
44
78
H21.0
ICD-10 Finland
Hyphaema
90.3
23.8
26
*
3661A
ICD-9 Finland
Cataract, Senile cataract
+∞
23.1
22
*
37870
ICD-8 Finland
Other diseases of eye, Subluxatio et luxatio lentis
+∞
23.1
22
*
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.5
22.8
30
37
ZXE00
NOMESCO Finland
One hour or less
2.3
22.4
261
1473
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
4.4
22.3
59
145
CKC12
NOMESCO Finland
Photocoagulation of retina
6.0
21.7
39
68
CKD15
NOMESCO Finland
Injection of vitreous substitute
119.1
21.7
23
*
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
27.5
21.5
29
11
A98
ICPC
Health maint/preventive medicine
3.3
21.3
570
4551
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
21.1
193
977
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
20.9
20
*
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
19.9
19
*
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
206.1
19.7
20
*
H20.1
ICD-10 Finland
Chronic iridocyclitis
32.4
19.4
25
8
H52.1
ICD-10 Finland
Myopia
8.6
19.4
25
30
CKC30
NOMESCO Finland
Cryopexy of detached retina
47.6
19.3
23
5
WX110
NOMESCO Finland
Infiltration anesthesia
2.1
19.1
394
2731
J01DB01
ATC
cefalexin; oral
2.4
19.0
500
3818
CG2T4
NOMESCO Finland
Topography assessment of cornea
28.8
18.8
25
9
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
+∞
18.8
18
*
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
+∞
18.8
18
*
3660C
ICD-9 Finland
Cataract, Infantile, juvenile and presenile cataract[CATARACTA PRAESENILIS]
+∞
18.8
18
*
CJD30
NOMESCO Finland
Pars plana lensectomy
+∞
18.8
18
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
5.4
18.4
37
72
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
18.3
256
1527
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
17.8
80
281
N02BE01
ATC
paracetamol; systemic, rectal
2.8
17.3
560
4570
L28
ICPC
Limited function/disability (L)
2.2
17.1
177
932
H04.10
ICD-10 Finland
Dry eye syndrome
3.2
17.1
73
248
CJW99
NOMESCO Finland
Other operation on lens
+∞
16.7
16
*
S18
ICPC
Laceration/cut
2.0
16.6
306
2001
CKC60
NOMESCO Finland
Local buckling of sclera using implant
30.9
16.2
21
7
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
17.3
16.2
25
15
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
61.6
15.8
18
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
34.3
15.8
20
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
15.7
336
2298
CJF35
NOMESCO Finland
Correcting the position of the artificial lens and attaching it to the sclera
+∞
15.7
15
*
ZXD05
NOMESCO Finland
Urgent procedure
2.1
15.7
215
1258
Z94.7
ICD-10 Finland
Corneal transplant status
163.8
15.5
16
*
SPAT1153
SPAT
Removal of sutures
2.0
14.8
211
1248
CJF99
NOMESCO Finland
Other operation on artificial lens
+∞
14.6
14
*
CJF50
NOMESCO Finland
Removal and implantation of artificial lens in posterior chamber
+∞
14.6
14
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
82.0
14.6
16
*
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.6
14.6
49
143
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
153.4
14.5
15
*
S01EB01
ATC
pilocarpine; ophthalmic
17.5
14.4
22
13
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
14.2
262
1687
CKC10
NOMESCO Finland
Local photocoagulation of retina
6.9
14.1
22
33
S01ED02
ATC
betaxolol; ophthalmic
16.2
14.0
22
14
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.8
13.9
76
296
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
20.6
13.8
20
10
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
13.6
123
607
CJG99
NOMESCO Finland
Other operation on dislocated lens
+∞
13.6
13
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
142.9
13.5
14
*
H27.8
ICD-10 Finland
Other specified disorders of lens
142.9
13.5
14
*
H18.1
ICD-10 Finland
Bullous keratopathy
142.9
13.5
14
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
13.4
63
226
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
26.4
13.4
18
7
S01FA01
ATC
atropine; ophthalmic
23.1
13.0
18
8
SPAT1254
SPAT
Administration of medicine
2.2
12.8
124
630
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
12.8
249
1621
I10
ICD-10 Finland
Essential (primary) hypertension
1.9
12.7
442
3442
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
12.7
186
1101
CHD00
NOMESCO Finland
Laser trabeculoplasty
11.3
12.6
23
21
3639
FHL
Other measure in this category
+∞
12.5
12
*
3793A
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[APHAKIA]
+∞
12.5
12
*
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
132.5
12.5
13
*
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.1
12.4
146
798
A02BC02
ATC
pantoprazole; systemic
1.9
12.1
419
3233
AA1AD
NOMESCO Finland
CT of head and brain
1.9
12.0
223
1423
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
11.9
149
831
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
11.9
244
1605
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
11.8
164
949
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
11.8
227
1464
H57.1
ICD-10 Finland
Ocular pain
4.6
11.8
28
63
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.0
11.6
54
193
SPAT1263
SPAT
Sampling
1.8
11.4
247
1649
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
8.3
11.2
24
30
SPAT1325
SPAT
Vaccination
1.8
11.1
234
1545
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
11.0
87
405
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.7
10.9
35
99
XCD20
NOMESCO Finland
Photoangiography of eye
9.8
10.8
21
22
CJF40
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber
+∞
10.4
10
*
H26.1
ICD-10 Finland
Traumatic cataract
+∞
10.4
10
*
A04
ICPC
Weakness/tiredness general
2.1
10.4
117
626
C07AB07
ATC
bisoprolol; oral
1.7
10.3
361
2740
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
10.2
176
1088
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.3
10.2
39
124
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
9.9
184
1162
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.5
9.9
66
284
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.8
9.8
19
20
H02AB06
ATC
prednisolone; systemic
1.7
9.7
293
2123
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
55.9
9.7
11
*
H20.8
ICD-10 Finland
Other iridocyclitis
55.9
9.7
11
*
J01CA04
ATC
amoxicillin; systemic
1.8
9.6
458
3750
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
9.6
84
407
Z3231
NOMESCO Finland
Registered nurse
1.8
9.5
182
1159
K02.1
ICD-10 Finland
Caries of dentine
1.7
9.4
277
1988
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
12.6
9.4
16
13
3631
FHL
Setting up an artificial lens as the only procedure
+∞
9.4
9
*
CJG20
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in posterior chamber
+∞
9.4
9
*
H18.2
ICD-10 Finland
Other corneal oedema
+∞
9.4
9
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
9.4
172
1080
H16.0
ICD-10 Finland
Corneal ulcer
3.7
9.3
30
85
D07AC01
ATC
betamethasone; topical
1.7
9.3
214
1435
SPAT1312
SPAT
General health counselling
1.8
9.3
176
1116
WW200, ,
SPAT
1.8
9.1
168
1055
S05.1
ICD-10 Finland
Contusion of eyeball and orbital tissues
10.2
9.1
17
17
H40.8
ICD-10 Finland
Other glaucoma
37.2
9.0
11
*
CHD35
NOMESCO Finland
Laser goniopuncture
18.9
9.0
13
7
R53
ICD-10 Finland
Malaise and fatigue
1.8
8.9
169
1071
C08CA01
ATC
amlodipine; oral
1.7
8.8
277
2013
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
8.8
120
685
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
50.7
8.7
10
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
50.7
8.7
10
*
TK800
NOMESCO Finland
Hemodialysis
4.7
8.6
20
44
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
8.6
216
1479
R4110, ,
SPAT
2.1
8.5
82
412
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.3
8.5
22
53
CKC20
NOMESCO Finland
Cryopexy of undetached retina
27.9
8.5
11
*
E0000UV, ,
ATC
1.7
8.5
232
1624
CFW99
NOMESCO Finland
Other operation on conjunctiva
91.2
8.4
9
*
37520
ICD-8 Finland
Glaucoma, Secondary
91.2
8.4
9
*
3643
FHL
Vitrectomy through pars Plana
91.2
8.4
9
*
B01AC04
ATC
clopidogrel; oral
1.9
8.4
132
788
H25.9
ICD-10 Finland
Senile cataract, unspecified
13.0
8.4
14
11
3642
FHL
Anterior vitrectomy
+∞
8.3
8
*
37405
ICD-8 Finland
Cataract, Traumatica
+∞
8.3
8
*
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
+∞
8.3
8
*
CJF60
NOMESCO Finland
Removal of an artificial lens, attachment of a new posterior chamber lens to the sclera
+∞
8.3
8
*
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
+∞
8.3
8
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
8.2
141
864
SPAT1234
SPAT
Support of social functional capacity
2.5
8.0
50
208
A46
ICD-10 Finland
Erysipelas
1.9
8.0
114
659
-44
ICPC
Preventive immunization/medic
2.3
7.9
63
293
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
7.9
115
669
R06.0
ICD-10 Finland
Dyspnoea
1.7
7.9
179
1187
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
7.8
341
2661
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
7.8
189
1275
XCW10
NOMESCO Finland
Assessment of vision
9.6
7.8
15
16
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
7.8
208
1440
H3603, E103,
ICD-10 Finland
45.5
7.7
9
*
D07AC13
ATC
mometasone; topical
1.7
7.6
160
1037
B01AB05
ATC
enoxaparin; parenteral
1.7
7.6
202
1394
S01XA18
ATC
ciclosporin; ophthalmic
25.3
7.6
10
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.6
7.6
44
177
N30.0
ICD-10 Finland
Acute cystitis
1.9
7.6
109
632
R06AE07
ATC
cetirizine; oral
1.6
7.5
219
1546
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.5
237
1706
C03CA01
ATC
furosemide; systemic
1.6
7.5
277
2071
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
3.2
7.5
29
93
T89
ICPC
Diabetes insulin dependent
3.6
7.5
24
68
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
7.5
21
54
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
81.0
7.4
8
*
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
81.0
7.4
8
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
7.4
255
1875
C01DA14
ATC
isosorbide mononitrate; oral
1.7
7.4
152
980
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.2
7.4
63
302
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.5
7.4
46
192
WZC00, ,
SPAT
2.0
7.3
81
429
SPAT1172
SPAT
Guidance concerning hydration
3.5
7.3
25
74
CJC15
NOMESCO Finland
Intracapsular cataract extraction with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
+∞
7.3
7
*
H26.3
ICD-10 Finland
Drug-induced cataract
+∞
7.3
7
*
3747
FHL
Combined ablation and vitreous surgery with coagulation
+∞
7.3
7
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
7.3
7
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.3
259
1916
XCD10
NOMESCO Finland
Electrophysiological examination of eye
5.9
7.3
19
33
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
7.2
93
519
H54.4
ICD-10 Finland
Blindness, monocular
30.4
7.2
9
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
20.3
7.1
10
5
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
20.3
7.1
10
5
J01MA02
ATC
ciprofloxacin; systemic
1.6
7.1
250
1841
WZC30
NOMESCO Finland
Teaching
1.9
7.1
104
605
SFA10
NOMESCO Finland
One-surface restoration
1.6
7.0
252
1866
DAX08
NOMESCO Finland
Fitting of hearing aid
2.4
7.0
47
203
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.6
7.0
41
166
P20
ICPC
Memory disturbance
1.8
7.0
126
782
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
7.0
69
351
H33.5
ICD-10 Finland
Other retinal detachments
14.0
6.9
11
8
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
14.0
6.9
11
8
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.5
6.9
23
67
C10AA07
ATC
rosuvastatin; oral
1.6
6.9
176
1199
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.8
114
691
37403
ICD-8 Finland
Cataract, Complicata
40.5
6.8
8
*
CFB00
NOMESCO Finland
Suture of conjunctiva
40.5
6.8
8
*
H40.12
ICD-10 Finland
Pigmentary glaucoma
40.5
6.8
8
*
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.4
6.8
24
73
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
6.7
95
546
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
6.7
128
805
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
6.7
84
464
H02AB04
ATC
methylprednisolone; systemic
1.9
6.7
85
472
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.7
230
1681
H50.1
ICD-10 Finland
Divergent concomitant strabismus
22.8
6.7
9
*
S01BA07
ATC
fluorometholone; ophthalmic
6.5
6.7
16
25
J01MA12
ATC
levofloxacin; systemic
1.7
6.6
127
800
M54.5
ICD-10 Finland
Low back pain
1.6
6.6
175
1200
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
6.6
58
281
N03AX16
ATC
[U] pregabalin
1.7
6.6
128
809
SPAT1216
SPAT
Assessment of functional ability
1.8
6.6
118
730
K29
ICPC
Cardiovascular sympt/complt other
2.7
6.6
35
135
SPAT1043
SPAT
Audiometry
2.0
6.5
73
388
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.2
6.5
25
80
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
6.5
161
1088
R01AD08
ATC
fluticasone; nasal
1.7
6.4
132
847
Q12.0
ICD-10 Finland
Congenital cataract
70.5
6.4
7
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
14.5
6.4
10
7
H34.8
ICD-10 Finland
Other retinal vascular occlusions
3.8
6.4
19
51
M79.6
ICD-10 Finland
Pain in limb
1.6
6.3
217
1582
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
11.2
6.3
11
10
Z01.9
ICD-10 Finland
Special examination, unspecified
2.6
6.3
37
150
R60.0
ICD-10 Finland
Localized oedema
1.9
6.3
88
505
3628
FHL
Intracapsular cataract surgery and implantation of an artificial lens
+∞
6.3
6
*
3662A
ICD-9 Finland
Cataract, Traumatic cataract
+∞
6.3
6
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
+∞
6.3
6
*
H31.3
ICD-10 Finland
Choroidal haemorrhage and rupture
+∞
6.3
6
*
37401
ICD-8 Finland
Cataract, Praesenilis
+∞
6.3
6
*
H40
ICD-10 Finland
Glaucoma
7.1
6.2
14
20
H16.9
ICD-10 Finland
Keratitis, unspecified
7.1
6.2
14
20
SPAT1211
SPAT
Application of soft bandage
2.2
6.2
52
247
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
6.2
24
77
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.2
152
1021
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
6.2
124
790
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.2
117
734
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.2
6.2
53
255
L08
ICPC
Shoulder symptom/complaint
1.7
6.2
120
759
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
6.2
102
616
EB1VA, ,
NOMESCO Finland
1.9
6.1
73
397
H26.9
ICD-10 Finland
Cataract, unspecified
10.1
6.0
11
11
H81
ICPC
Excessive ear wax
1.7
6.0
120
763
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.0
166
1147
H13
ICPC
Plugged feeling ear
1.7
6.0
126
813
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
319
1829
2.48
27.86
4.0
3.2
2445.15
1833.85
ng/l
0.78
283
1606
580
4538
3.92
25.56
30.6
23.0
139.27
139.50
mmol/l
1.16
567
4424
543
4094
3.13
25.34
25.8
19.2
69.11
72.79
ml/min/173m2
3.58
511
3820
580
4546
3.90
25.31
31.2
23.2
4.02
4.01
mmol/l
0.54
567
4423
582
4621
3.82
23.79
33.3
24.9
91.61
83.37
umol/l
2.76
574
4533
493
3599
2.60
23.32
9.5
8.2
84.02
82.88
u/l
0.17
462
3374
583
4664
3.76
22.89
37.7
28.0
239.32
241.10
e9/l
0.24
573
4531
583
4665
3.76
22.86
37.6
27.9
92.62
91.63
fl
4.71
575
4577
583
4666
3.76
22.83
37.6
27.9
4.26
4.38
e12/l
5.98
568
4517
583
4666
3.76
22.83
38.9
28.5
38.60
39.32
%
1.88
575
4572
583
4667
3.75
22.80
37.9
28.2
129.35
131.88
g/l
3.28
576
4580
570
4510
3.38
22.55
15.2
12.3
25.02
24.99
u/l
0.01
542
4336
465
3333
2.44
22.41
5.4
4.1
16.47
14.97
mm/h
1.00
421
3078
381
2515
2.27
22.25
23.7
17.9
1.38
1.35
inr
0.36
336
2099
556
4370
3.05
21.61
26.3
18.7
26.46
28.79
mg/l
1.08
491
3694
417
2935
2.20
19.74
6.7
5.2
6.88
6.75
mmol/l
0.66
398
2783
514
3953
2.52
19.59
6.3
5.2
2.13
2.10
mu/l
0.09
458
3574
194
1013
2.31
19.50
1.8
1.8
1053.14
1181.09
nmol/l
1.15
139
749
313
1979
2.14
19.49
5.2
4.2
239.38
57.86
ng/l
0.45
266
1537
319
2046
2.11
18.97
2.8
2.3
78.97
79.49
nmol/l
0.11
273
1798
379
2609
2.11
18.48
5.9
6.7
11.77
12.79
umol/l
1.13
357
2487
383
2652
2.10
18.32
9.8
7.2
1.21
1.21
mmol/l
0.79
312
2275
519
4065
2.45
18.02
7.7
6.8
40.65
40.01
mmol/mol
0.83
462
3731
527
4171
2.48
17.61
6.4
5.9
2.42
2.55
mmol/l
2.99
467
3773
343
2313
2.04
17.24
2.4
2.2
96.46
94.25
pmol/l
0.34
186
1188
515
4073
2.35
16.59
5.7
5.1
4.28
4.44
mmol/l
2.99
453
3704
512
4049
2.31
16.33
5.7
5.0
1.42
1.44
mmol/l
0.50
450
3662
368
2608
1.97
15.37
3.9
3.2
71.09
54.77
u/l
1.39
332
2390
436
3280
2.03
15.28
4.9
4.1
15.47
15.17
pmol/l
1.66
384
2943
374
2669
1.96
15.27
10.2
9.2
4.48
4.37
e9/l
0.36
335
2282
493
3889
2.16
15.05
4.9
4.3
1.31
1.26
mmol/l
0.68
428
3468
118
551
2.40
14.95
3.7
3.7
—
—
—
0
0
298
1995
1.92
14.47
3.9
2.9
170.43
158.28
ug/l
0.40
264
1813
230
1417
1.97
14.24
2.8
2.2
2.98
2.96
mg/l
0.03
189
1199
512
4144
2.17
13.92
6.0
5.3
6.14
6.07
mmol/l
0.56
438
3729
335
2357
1.88
13.71
9.2
6.5
1.21
1.21
mmol/l
0.37
302
2165
243
1572
1.88
12.68
2.0
1.7
20.12
19.95
nmol/l
0.06
198
1327
332
2371
1.83
12.57
5.5
5.0
34.13
34.52
g/l
0.60
308
2198
315
2233
1.81
12.05
2.9
2.8
—
—
estimate
—
0
0
201
1249
1.89
11.71
2.8
2.4
—
—
—
0
0
239
1571
1.83
11.63
2.4
2.1
194.85
270.69
u/l
0.71
230
1469
332
2409
1.78
11.58
4.7
4.2
0.00
0.00
estimate
-0.00
87
563
230
1496
1.84
11.57
2.6
2.5
58.12
116.87
u/l
0.56
210
1384
78
339
2.48
11.45
3.9
3.9
5.08
5.20
kpa
0.36
73
323
70
290
2.59
11.35
3.7
3.9
1.93
2.18
mmol/l
0.18
50
215
336
2463
1.77
11.17
4.7
4.2
0.05
0.55
estimate
0.44
85
543
54
200
2.86
10.86
2.4
2.0
—
—
—
0
0
51
185
2.91
10.65
2.3
1.9
—
—
—
0
0
330
2437
1.73
10.43
4.8
4.2
0.00
9.05
estimate
1.04
91
576
103
527
2.14
10.29
5.3
5.0
33.49
33.06
%
0.12
63
309
264
1847
1.73
10.02
3.3
3.4
2.34
2.36
mmol/l
1.73
233
1631
95
482
2.14
9.68
2.7
2.3
6.40
6.84
ug/l
0.14
78
409
173
1091
1.80
9.30
1.8
1.8
479.06
429.43
pmol/l
1.46
145
885
154
938
1.84
9.27
3.7
2.5
11.48
11.78
umol/l
0.23
137
869
146
879
1.86
9.11
3.6
2.4
2.13
2.23
g/l
1.26
131
810
119
672
1.95
9.02
3.0
4.3
252.68
253.92
u/l
0.03
108
641
47
181
2.72
8.80
4.0
4.6
24.46
25.33
mmol/l
1.13
42
164
86
440
2.10
8.55
6.1
3.6
1.23
1.23
mmol/l
0.15
75
373
180
1178
1.73
8.41
3.3
2.9
371.86
357.52
umol/l
0.97
145
1016
135
816
1.83
8.25
3.8
2.5
21.02
21.44
%
0.16
121
758
62
290
2.26
7.70
1.9
1.6
1.51
1.65
g/l
0.50
51
258
182
1230
1.67
7.42
3.4
2.7
5.22
5.08
e6/l
0.05
169
1115
125
762
1.80
7.37
8.8
5.1
1.03
1.02
mmol/l
0.22
115
694
198
1381
1.63
7.08
4.9
4.3
0.00
0.00
estimate
-0.00
80
493
141
906
1.71
6.89
3.4
3.0
0.83
0.81
mmol/l
0.51
132
843
273
2076
1.55
6.66
2.7
2.5
—
—
—
0
0
66
343
2.03
6.28
3.1
3.1
60.33
60.47
ml/min/173m2
0.01
33
150
153
1029
1.64
6.23
2.1
1.9
—
—
—
0
0
240
1796
1.54
6.18
4.5
4.3
0.03
0.03
estimate
0.00
71
458
223
1651
1.54
5.99
4.1
3.2
6.36
7.10
mmol/l
2.57
181
1384
85
491
1.84
5.93
11.7
6.0
12.82
10.63
mmol/l
1.47
80
471
30
115
2.69
5.72
1.2
1.2
—
—
—
0
0
225
1684
1.52
5.69
4.9
3.9
12.43
9.44
mg/mmol
0.32
135
1055
171
1208
1.57
5.61
3.3
3.1
2.46
2.47
mmol/l
0.36
152
1061
86
516
1.77
5.29
2.5
2.2
0.19
0.20
g/l
0.43
75
474
142
973
1.59
5.28
1.8
1.7
1.50
1.46
mg/l
0.04
115
784
229
1744
1.49
5.24
4.6
3.6
45.10
71.45
e6/l
0.79
195
1334
206
1537
1.50
5.20
4.5
3.5
0.36
0.58
e6/l
1.36
172
1143
58
310
1.96
5.12
1.4
1.4
—
—
—
0
0
126
845
1.61
5.12
1.5
1.2
0.94
1.19
u/ml
0.51
37
211
42
200
2.18
5.04
3.3
3.6
46.39
83.18
mg/l
0.64
36
171
42
200
2.18
5.04
3.3
3.6
35.11
99.58
mg/l
0.58
36
172
70
407
1.81
4.79
1.7
1.5
—
—
—
0
0
23
86
2.74
4.63
5.8
2.6
14.70
9.59
pmol/l
0.73
23
86
38
183
2.14
4.46
3.3
3.6
1.33
9.44
ratio
0.97
23
99
90
579
1.64
4.30
7.6
7.9
—
—
—
0
0
16
51
3.19
4.23
2.0
2.0
90.67
89.50
%
0.46
16
51
232
1830
1.42
4.22
5.9
5.8
7.00
6.94
ug/l
0.00
207
1622
27
117
2.37
4.07
1.6
1.4
—
—
—
0
0
69
420
1.72
4.05
2.2
2.0
395.38
389.78
nmol/l
0.06
61
382
125
884
1.51
3.98
1.8
2.0
29.29
29.70
s
0.42
118
865
166
1244
1.45
3.95
4.5
3.6
0.04
0.11
estimate
0.41
70
421
30
139
2.22
3.89
4.9
2.7
1.99
1.62
mg/l
1.49
25
129
37
187
2.04
3.86
2.8
2.5
—
—
—
0
0
32
154
2.13
3.79
1.3
1.7
—
—
—
0
0
83
542
1.61
3.74
2.2
2.9
217.99
263.66
ng/l
0.55
74
499
14
39
3.65
3.72
1.6
1.8
—
—
—
0
0
27
123
2.25
3.65
2.0
1.6
—
—
—
0
0
78
505
1.62
3.64
2.7
2.7
65.83
65.79
g/l
0.02
69
474
33
165
2.05
3.56
1.4
1.8
—
—
—
0
0
44
245
1.85
3.50
2.0
1.9
0.81
1.40
ug/l
0.65
36
207
402
3540
1.36
3.50
30.8
23.8
14.10
13.93
%
1.59
397
3488
33
169
2.00
3.35
3.0
3.6
0.77
0.81
nmol/l
0.28
25
143
15
54
2.82
3.27
2.8
2.5
—
—
—
0
0
67
433
1.61
3.17
5.6
3.6
134.74
97.59
ng/l
1.26
53
369
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
225
1.83
3.10
4.4
2.2
0.42
0.34
iu/ml
0.46
17
119
36
196
1.89
3.09
2.6
2.1
483.39
712.64
ug/l
0.33
36
190
32
171
1.92
2.91
1.6
2.3
43.04
36.95
u/l
0.84
26
151
145
1119
1.38
2.86
4.7
4.1
910.90
337.92
ng/l
0.52
127
981
41
239
1.76
2.85
2.7
2.5
4.21
4.19
g/l
0.04
33
225
41
239
1.76
2.85
2.7
2.5
3.42
3.68
g/l
0.85
33
225
41
239
1.76
2.85
2.7
2.5
7.69
7.56
g/l
0.18
33
225
39
226
1.77
2.77
2.8
2.6
2.85
3.08
g/l
0.78
31
212
5
6
8.39
2.75
1.0
1.2
—
—
—
0
0
17
73
2.36
2.67
1.2
1.3
—
—
—
0
0
11
35
3.18
2.65
1.6
1.4
—
—
—
0
0
15
61
2.49
2.63
1.4
1.2
—
—
—
0
0
27
144
1.91
2.50
2.8
2.3
125.09
128.48
g/l
0.28
22
111
61
410
1.54
2.48
2.1
1.7
—
—
—
0
0
27
145
1.90
2.45
1.3
1.5
243.31
273.89
ug/g
0.34
16
92
36
214
1.72
2.37
2.8
2.6
10.15
10.26
g/l
0.06
27
198
8
23
3.51
2.27
1.6
1.3
86.38
90.65
umol/l
—
8
23
82
597
1.43
2.26
5.7
3.4
1.13
1.83
mmol/l
0.97
70
496
7
18
3.92
2.25
1.1
1.0
—
—
—
0
0
24
128
1.91
2.24
1.6
1.5
4.14
0.08
iu/ml
—
5
22
9
29
3.13
2.23
1.2
1.2
—
—
—
0
0
25
138
1.84
2.12
1.2
1.5
2.17
10.30
iu/ml
—
7
30
91
687
1.38
2.05
9.6
7.4
1.28
0.75
mmol/l
0.71
76
560
195
1642
1.27
2.02
2.0
1.9
1.34
1.31
mmol/l
0.23
146
1369
13
57
2.31
1.99
1.3
1.2
161.88
275.84
u/ml
—
8
31
18
91
2.01
1.97
1.2
1.4
51431.77
35057.31
e6/l
0.18
13
51
50
341
1.51
1.94
2.1
1.8
1.82
1.59
%
1.25
39
281
176
1471
1.27
1.93
2.9
3.3
34.74
33.42
u/l
0.22
163
1404
121
964
1.31
1.92
4.2
3.2
1.18
1.21
e6/l
0.03
73
514
17
85
2.03
1.92
1.2
1.2
58.70
1.83
u/ml
—
5
6
17
85
2.03
1.92
1.2
1.2
3.15
9.34
u/ml
—
6
11
29
174
1.70
1.89
1.1
1.1
—
—
—
0
0
8
28
2.88
1.86
1.1
1.1
—
—
—
0
0
6
17
3.55
1.84
1.0
1.2
—
—
—
0
0
6
17
3.55
1.84
5.3
1.7
202.00
207.24
u/l
—
6
17
5
12
4.19
1.82
1.2
1.0
621.00
187.88
iu/ml
—
5
12
7
23
3.07
1.80
1.4
1.2
18.57
20.94
u/l
—
7
18
8
29
2.78
1.79
1.5
1.5
—
—
—
0
0
175
1477
1.25
1.76
5.0
4.8
20.00
21.19
%
0.51
91
778
90
696
1.34
1.76
9.7
7.4
11.22
12.28
kpa
1.52
84
665
6
18
3.35
1.75
1.2
1.3
—
—
—
0
0
8
30
2.69
1.73
1.3
1.2
—
—
—
0
0
23
133
1.76
1.72
1.3
1.5
—
—
—
0
0
78
593
1.36
1.70
2.4
2.6
7.67
8.47
umol/l
0.23
68
520
34
220
1.58
1.68
4.0
2.6
1.36
1.18
g/l
0.08
25
193
42
286
1.50
1.67
2.5
3.9
1.02
1.02
ratio
0.07
34
265
7
25
2.82
1.65
1.6
1.6
—
—
—
0
0
7
25
2.82
1.65
1.6
1.5
—
—
—
0
0
112
903
1.29
1.63
4.2
3.3
1.69
2.60
e6/l
0.67
61
454
99
786
1.31
1.62
1.9
1.8
—
—
—
0
0
8
33
2.44
1.54
2.8
2.2
—
—
—
0
0
23
138
1.69
1.53
4.5
3.4
1.38
1.97
index
0.23
13
68
82
643
1.32
1.48
3.2
4.5
25.87
23.55
ug/l
0.04
65
538
10
45
2.24
1.47
3.9
2.7
6.60
12.10
index
—
5
21
54
397
1.39
1.46
2.5
2.4
0.53
0.37
e6/l
0.31
49
383
22
133
1.68
1.44
1.1
1.2
0.33
1.05
u/ml
—
6
11
32
214
1.52
1.41
1.1
1.2
180.49
123.19
u/ml
0.34
14
71
127
1060
1.25
1.40
3.5
3.5
0.63
0.79
ug/l
2.45
93
741
124
1042
1.24
1.29
4.3
4.4
1.02
1.02
kg/l
0.16
87
663
5
18
2.79
1.28
1.2
1.2
38.48
40.08
g/l
—
5
18
63
487
1.33
1.27
2.7
2.6
42.04
34.28
u/l
0.31
54
408
6
25
2.41
1.24
1.0
1.2
—
—
—
0
0
6
25
2.41
1.24
1.0
1.2
—
—
—
0
0
5
19
2.64
1.22
1.0
1.0
—
—
—
0
0
8
37
2.18
1.21
1.8
1.7
—
—
—
0
0
14
79
1.79
1.17
1.3
1.6
—
—
—
0
0
10
50
2.02
1.17
1.0
1.3
—
—
—
0
0
5
21
2.39
1.09
4.8
2.7
1.00
0.76
index
—
5
21
5
21
2.39
1.09
1.0
1.2
—
—
—
0
0
27
186
1.47
1.08
3.6
2.6
0.00
0.00
g/l
-0.00
20
163
16
97
1.67
1.07
2.5
1.8
2.70
4.51
iu/l
—
7
36
20
129
1.57
1.06
3.6
3.4
26.14
2336.89
u/ml
0.65
15
121
19
121
1.59
1.06
2.3
1.6
47728.10
17026.40
e6/l
—
10
83
25
171
1.48
1.04
3.6
2.7
0.00
0.00
g/l
-0.00
20
162
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
18
116
1.57
0.97
1.3
1.1
—
—
—
0
0
18
117
1.55
0.94
1.3
1.1
—
—
—
0
0
10
55
1.83
0.92
1.4
1.5
—
—
—
0
0
6
28
2.15
0.91
1.2
1.4
5.83
2.32
u/field
—
6
19
27
194
1.41
0.89
3.6
2.5
0.00
0.02
g/l
0.80
20
173
13
79
1.66
0.88
1.3
1.6
—
—
—
0
0
27
195
1.40
0.87
1.4
1.2
—
—
—
0
0
8
43
1.87
0.87
1.3
1.4
—
—
—
0
0
6
30
2.01
0.87
1.5
1.4
—
—
—
0
0
6
30
2.01
0.87
1.5
1.4
—
—
—
0
0
15
96
1.58
0.85
1.3
1.5
—
—
—
0
0
10
57
1.77
0.84
1.5
1.5
—
—
—
0
0
10
57
1.77
0.84
1.5
1.5
—
—
—
0
0
42
330
1.29
0.81
1.4
1.4
—
—
—
0
0
32
242
1.34
0.80
3.0
2.5
28.80
24.05
au/ml
—
5
15
10
58
1.74
0.80
1.6
1.6
—
—
—
0
0
49
396
1.26
0.77
1.4
1.4
—
—
—
0
0
9
55
1.65
0.73
1.6
1.5
—
—
—
0
0
9
56
1.62
0.72
1.6
1.5
—
—
—
0
0
9
56
1.62
0.72
1.6
1.5
—
—
—
0
0
7
40
1.76
0.71
1.1
1.8
—
—
—
0
0
7
40
1.76
0.71
1.4
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
1.7
—
—
—
0
0
7
40
1.76
0.71
1.0
1.7
—
—
—
0
0
7
40
1.76
0.71
1.0
1.7
—
—
—
0
0
12
77
1.57
0.69
1.5
1.8
—
—
—
0
0
17
119
1.44
0.67
1.4
1.5
—
—
—
0
0
7
44
1.60
0.65
1.3
1.2
—
—
—
0
0
17
121
1.42
0.63
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
71
617
1.17
0.57
1.3
1.3
13.30
13.98
u/ml
0.02
27
199
11
73
1.52
0.56
1.0
1.2
—
—
—
0
0
75
656
1.16
0.56
1.4
1.3
33.36
47.10
iu/ml
0.58
22
196
17
124
1.38
0.56
1.4
1.6
—
—
—
0
0
20
151
1.33
0.54
1.3
1.3
—
—
—
0
0
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
10
66
1.52
0.52
2.4
2.5
11.60
10.24
mmol/l
—
10
66
10
66
1.52
0.52
1.4
1.6
—
—
—
0
0
9
64
1.41
0.51
3.4
3.9
—
—
—
0
0
19
146
1.31
0.47
1.6
1.5
0.37
0.29
mg/l
—
8
64
7
48
1.46
0.47
1.3
1.2
0.19
0.20
nmol/l
—
7
42
5
31
1.62
0.43
1.4
1.2
65.40
101.61
pmol/l
—
5
31
15
113
1.34
0.43
1.5
1.2
—
—
—
0
0
8
58
1.38
0.41
1.5
1.6
—
—
—
0
0
8
61
1.32
0.39
1.8
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
16.20
—
0
6
9
68
1.33
0.37
1.7
1.4
—
—
—
0
0
6
43
1.40
0.35
1.0
1.8
—
—
—
0
0
81
744
1.10
0.32
2.0
1.8
—
—
—
0
0
11
83
1.33
0.32
1.4
1.3
—
—
—
0
0
7
54
1.30
0.30
1.3
1.2
—
0.52
nmol/l
—
0
5
8
63
1.27
0.28
1.3
1.4
—
274.43
—
0
28
5
40
1.25
0.22
1.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
12.82
—
0
11
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
9
114
0.79
0.20
2.0
1.7
44.78
43.35
nmol/l
—
9
108
15
128
1.18
0.18
4.1
2.2
70.07
59.54
%
1.42
15
128
7
58
1.21
0.18
1.0
1.1
1.36
1.55
g/l
—
7
58
7
90
0.78
0.14
1.9
1.8
206.29
213.01
pmol/l
—
7
80
5
63
0.79
0.08
1.6
2.2
2381.80
1071.06
mg
—
5
63
7
64
1.09
0.08
1.0
1.2
0.82
0.92
g/l
—
7
64
9
84
1.07
0.07
2.6
2.1
—
—
—
0
0
18
167
1.08
0.07
2.3
1.7
—
—
—
0
0
49
473
1.04
0.06
1.4
1.4
—
—
—
0
0
20
188
1.07
0.05
2.3
1.8
—
—
—
0
0
15
140
1.07
0.04
1.6
1.4
—
—
—
0
0
10
107
0.93
0.02
1.5
1.3
764.10
615.92
mg/l
—
10
102
24
238
1.01
0.00
2.9
3.5
8018.39
5499.95
u/ml
0.11
18
205
13
131
0.99
0.00
1.4
1.3
—
—
—
0
0
13
131
0.99
0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
8.07
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
87.72
—
0
5
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
-0.00
0.0
1.0
—
110.00
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.4
—
10.64
—
0
7
5
54
0.93
-0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
2.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
7
76
0.92
-0.00
6.6
4.2
46.86
38.47
u/ml
—
7
76
6
67
0.89
-0.00
1.3
1.7
356.72
944.59
mu/l
—
6
59
0
6
0.00
-0.00
0.0
1.0
—
0.24
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
2.6
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
91
0.99
-0.00
1.6
1.3
3.42
3.83
mmol/l
—
9
86
Mortality – FinRegistry
↥Association
Association between endpoint H7_LENSDISLOCATIO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LENSDISLOCATIO | 1.052 [0.92, 1.2] | 0.453 |
| Birth year | 0.994 [0.99, 1.0] | 0.142 |
During the follow-up period (1.1.1998 — 31.12.2019), 976 out of 2298 females with H7_LENSDISLOCATIO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_LENSDISLOCATIO | 1.095 [0.92, 1.3] | 0.293 |
| Birth year | 0.986 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 628 out of 1783 males with H7_LENSDISLOCATIO died.
Mortality risk
Mortality risk for people of age
years, who have H7_LENSDISLOCATIO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.2% |
| 5 | 0.743% | 1.17% |
| 10 | 1.606% | 3.076% |
| 15 | 2.894% | 5.677% |
| 20 | 5.148% | 10.003% |
Relationships between endpoints
↥Index endpoint: H7_LENSDISLOCATIO – Dislocation of lens
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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