chronic myeloproliferative disorder: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1473 |
4. Check minimum number of eventsNone |
1473 |
5. Include endpointsNone |
1473 |
6. Filter based on genotype QC (FinnGen only) |
1303 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Polycythaemia vera
based on the number of shared cases.
Similar with more cases:
- Myeloproliferative diseases
- Liquid cancers
- Liquid cancers, including Hilmo
- Malignant neoplasm
- Malignant neoplasm
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8645 | 4398 | 4141 |
| Only index persons | 6571 | 3383 | 3188 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.13 | 0.12 |
| Only index persons | 0.12 | 0.12 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 67.45 | 69.26 | 65.58 |
| Only index persons | 67.11 | 69.04 | 65.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1303 | 625 | 678 |
| Unadjusted period prevalence (%) | 0.27 | 0.22 | 0.31 |
| Median age at first event (years) | 66.05 | 65.67 | 66.40 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1337
- Matched controls
- 13370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
+∞
307.7
467
*
L01XX05
ATC
hydroxycarbamide; oral
5343.4
307.7
894
5
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2561.7
307.7
932
12
TPH00
NOMESCO Finland
Phlebotomy
1055.9
307.7
432
6
D75.2
ICD-10 Finland
Essential thrombocytosis
188.1
307.7
165
10
D45
ICD-10 Finland
Polycythaemia vera
4503599627370496.0
307.7
1305
5
XW000
NOMESCO Finland
Bone marrow biopsy
38.8
307.7
381
136
B99
ICPC
Blood/lymph/spleen disease other
166.3
299.6
148
10
SPAT1074
SPAT
Venesection
488.2
285.3
275
7
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
+∞
253.4
235
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
78.9
252.0
135
19
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
+∞
193.6
181
*
D75.1
ICD-10 Finland
Secondary polycythaemia
47.9
180.5
106
24
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
73.3
164.4
89
13
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
49.7
144.4
84
18
TPH00, ,
SPAT
275.5
124.3
125
5
L03AB05
ATC
interferon alfa-2b; parenteral
+∞
122.8
116
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.7
121.1
342
906
M04AA01
ATC
allopurinol; systemic
4.0
105.5
388
1240
L01XX35
ATC
anagrelide; oral
+∞
100.3
95
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
92.8
88
*
B28
ICPC
Limited function/disability (B)
26.4
90.6
63
25
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
+∞
89.6
85
*
174
Kela drug reimbursment
Ruxolitinib
+∞
86.4
82
*
WW500
NOMESCO Finland
Blood transfusion
10.2
82.8
96
101
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
82.1
78
*
374
Kela drug reimbursment
Ruxolitinib
+∞
82.1
78
*
L03AB04
ATC
interferon alfa-2a; parenteral
+∞
80.0
76
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
410.8
78.7
78
*
212
Kela drug reimbursment
Gout
9.1
76.9
97
114
L01EJ01
ATC
ruxolitinib; oral
+∞
76.8
73
*
B04
ICPC
Blood symptom/complaint
26.2
76.1
53
21
H02AB02
ATC
dexamethasone; systemic
11.1
73.1
79
75
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
+∞
68.3
65
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
67.0
205
562
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
+∞
65.1
62
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.1
64.3
118
210
B74
ICPC
Malignant neoplasm blood other
647.7
63.4
62
*
115
Kela drug reimbursment
Breast cancer
+∞
54.5
52
*
PJA12
NOMESCO Finland
Sentinel node biopsy
527.6
51.8
51
*
130
Kela drug reimbursment
Malignant tumour
+∞
50.3
48
*
116
Kela drug reimbursment
Prostate cancer
+∞
47.2
45
*
B01AB05
ATC
enoxaparin; parenteral
2.4
46.9
494
2654
D75.0
ICD-10 Finland
Familial erythrocytosis
97.4
43.0
47
5
L01XE18
ATC
[U] ruxolitinib
+∞
42.9
41
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
42.9
41
*
A04AA01
ATC
ondansetron; systemic, rectal
5.6
42.8
83
155
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
12.5
39.4
39
32
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
88.9
39.0
43
5
JN4AD
NOMESCO Finland
Body CT examination
3.4
38.0
145
456
L57.0
ICD-10 Finland
Actinic keratosis
3.0
37.6
189
701
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
+∞
36.6
35
*
XX3DW
NOMESCO Finland
Time consuming IT work
3.9
35.6
110
300
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
34.5
33
*
WF002
NOMESCO Finland
Radical radiotherapy
51.5
33.6
40
8
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
4.7
33.5
79
175
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
33.1
425
2410
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
33.0
732
5046
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
45.7
32.9
40
9
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
32.7
141
477
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
32.4
31
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
55.8
32.4
38
7
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
41.2
32.3
40
10
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
31.4
30
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
10.5
30.8
34
33
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
30.5
205
880
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.4
29.3
49
79
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
29.3
28
*
2384A
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Polycythaemia vera
+∞
29.3
28
*
L02BG04
ATC
letrozole; oral
31.7
28.2
37
12
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
28.2
27
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
26.3
198
892
A04AA02
ATC
granisetron; systemic, transdermal
74.2
25.9
29
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.0
25.7
56
116
Z51.5
ICD-10 Finland
Palliative care
3.2
25.6
106
349
B03XA02
ATC
darbepoetin alfa; parenteral
6.0
25.4
45
77
HA1AA
NOMESCO Finland
X-ray mammography
4.1
25.3
70
176
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
24.8
134
513
ZX120
NOMESCO Finland
Intravenous
2.9
24.0
122
452
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
244.2
23.7
24
*
HAC20
NOMESCO Finland
Total mastectomy
127.3
23.7
25
*
JN4BD
NOMESCO Finland
Extensive body CT
3.3
23.5
93
298
ZZR00
NOMESCO Finland
Flap of skin
18.9
23.1
35
19
ZX112
NOMESCO Finland
Subcutaneous
9.2
23.0
28
31
R50.9
ICD-10 Finland
Fever, unspecified
2.2
22.5
213
1056
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
53.0
22.1
26
5
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
21.9
21
*
L03AA04, ,
ATC
+∞
21.9
21
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
21.9
21
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
116.9
21.6
23
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.9
21.3
102
365
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.3
21.0
183
875
HAB40
NOMESCO Finland
Wedge excision of mammary gland
18.2
20.9
32
18
L01AB01
ATC
busulfan; systemic
+∞
20.9
20
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
20.9
20
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
20.9
20
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
20.9
20
*
B75
ICPC
Neoplasm blood benign/unspecified
213.2
20.6
21
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
213.2
20.6
21
*
L03AA13
ATC
pegfilgrastim; parenteral
111.8
20.6
22
*
TQW99
NOMESCO Finland
Other minor procedure on skin
3.4
20.5
77
239
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
19.8
19
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
19.8
19
*
C90.0
ICD-10 Finland
Multiple myeloma
+∞
19.8
19
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
106.6
19.6
21
*
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
106.6
19.6
21
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
202.9
19.6
20
*
Y77
ICPC
Malignant neoplasm prostate
202.9
19.6
20
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
19.2
428
2821
L02AE02
ATC
leuprorelin; implant, parenteral
26.5
19.2
26
10
JN4CD
NOMESCO Finland
Very extensive body CT
5.6
18.9
36
66
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
18.8
18
*
20899
ICD-8 Finland
Polycythaemia vera
+∞
18.8
18
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.8
18.4
97
366
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
44.7
18.3
22
5
B01AB10
ATC
tinzaparin; parenteral
2.4
17.8
130
575
WZC30
NOMESCO Finland
Teaching
2.1
17.8
186
954
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
17.7
17
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.1
17.6
75
251
NK6AN
NOMESCO Finland
Total body bone isotope imaging
29.2
17.4
23
8
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
17.3
103
414
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.9
17.2
83
299
R04.0
ICD-10 Finland
Epistaxis
2.3
17.1
138
638
L03AA02
ATC
filgrastim; parenteral
50.7
17.0
20
*
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.3
17.0
65
204
ZY010
NOMESCO Finland
Hospital outpatient
3.3
16.7
64
201
PH_2
NOMESCO Finland
Other procedures on veins
+∞
16.7
16
*
B01AA03
ATC
warfarin; systemic
1.7
16.6
354
2287
I81
ICD-10 Finland
Portal vein thrombosis
18.2
16.5
25
14
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.2
16.4
43
104
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
13.0
16.2
28
22
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
48.1
16.0
19
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
15.9
98
400
Z3231
NOMESCO Finland
Registered nurse
1.7
15.8
343
2223
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
33.8
15.8
20
6
ZX090
NOMESCO Finland
Other technic of radiotherapy
33.8
15.8
20
6
XQ848
NOMESCO Finland
Dermatological photography
3.8
15.7
48
130
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
15.7
15
*
L02BG03
ATC
anastrozole; oral
+∞
15.7
15
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
15.7
15
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
86.1
15.6
17
*
R71
ICD-10 Finland
Abnormality of red blood cells
19.5
15.6
23
12
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
161.8
15.5
16
*
S97
ICPC
Chronic ulcer skin
2.3
15.4
127
592
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
15.2
121
555
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
14.6
14
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
14.6
14
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
14.6
14
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
81.0
14.6
16
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.1
14.6
40
100
D73.5
ICD-10 Finland
Infarction of spleen
36.5
14.5
18
5
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
13.9
174
949
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
13.7
285
1817
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
4.4
13.6
34
79
K99
ICPC
Cardiovascular disease other
2.9
13.6
63
222
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
+∞
13.6
13
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
13.6
13
*
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
34.4
13.5
17
5
C03CA01
ATC
furosemide; systemic
1.6
13.5
514
3809
A46
ICD-10 Finland
Erysipelas
1.8
13.5
231
1393
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
141.4
13.5
14
*
N02AA05
ATC
oxycodone; systemic
1.8
13.2
234
1425
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
13.1
166
908
A79
ICPC
Malignancy NOS
50.5
12.9
15
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
5.5
12.6
24
44
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
70.5
12.6
14
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
12.5
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
12.5
12
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
12.5
12
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
12.5
12
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
12.5
12
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
12.5
12
*
L02BB03
ATC
bicalutamide; oral
+∞
12.5
12
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
12.5
12
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.9
12.5
37
98
ZXC50
NOMESCO Finland
Cryotherapy
3.5
12.4
43
127
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
12.3
79
329
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
4.8
12.2
27
57
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
12.1
65
248
D68.8
ICD-10 Finland
Other specified coagulation defects
5.9
11.8
21
36
J01DB01
ATC
cefalexin; oral
1.6
11.8
1020
8928
L71.9
ICD-10 Finland
Rosacea, unspecified
3.3
11.7
43
132
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.2
11.6
31
76
C50
ICD-10 Finland
Malignant neoplasm of breast
65.5
11.6
13
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.6
301
2025
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
11.5
11
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
11.5
11
*
WF004
NOMESCO Finland
Palliative radiotherapy
121.0
11.4
12
*
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
3.4
11.3
41
125
K29
ICPC
Cardiovascular sympt/complt other
2.3
11.3
87
394
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
25.2
11.1
15
6
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
25.2
11.1
15
6
L02BA01
ATC
tamoxifen; oral
43.7
10.9
13
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
43.7
10.9
13
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
43.7
10.9
13
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
10.9
193
1171
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.1
10.7
29
72
X76
ICPC
Malignant neoplasm breast female
60.5
10.6
12
*
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
5.3
10.6
21
40
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
110.9
10.4
11
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
10.4
10
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
10.4
10
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
10.4
10
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
10.4
10
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
12.1
10.4
18
15
G04BE03
ATC
sildenafil; oral
8.9
10.3
21
24
127
Kela drug reimbursment
Transplant complication
5.0
10.3
22
45
B01AB04
ATC
dalteparin; parenteral
2.5
10.1
63
259
D06BB10
ATC
imiquimod; topical
2.4
10.0
67
285
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
10.7
9.8
18
17
SPAT1088
SPAT
Blood transfusion
13.5
9.7
16
12
ZXC20
NOMESCO Finland
Use of chemical agents
4.0
9.6
27
69
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
15.1
9.5
15
10
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
9.5
229
1506
128
Kela drug reimbursment
Cancers of female genital organs
+∞
9.4
9
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
9.4
9
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
9.4
9
*
B86
ICPC
OTHER HAEMATOLOGICAL ABNORMALITY
+∞
9.4
9
*
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
+∞
9.4
9
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
9.4
9
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
9.4
9
*
L01BC06
ATC
capecitabine; oral
+∞
9.4
9
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
9.4
9
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
9.4
9
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
9.4
9
*
XKD00
NOMESCO Finland
Uroflowmetry
1.7
9.4
191
1203
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
9.3
234
1554
UJF32
NOMESCO Finland
Coloscopy
1.5
9.3
324
2321
D58.2
ICD-10 Finland
Other haemoglobinopathies
36.9
9.0
11
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
9.0
309
2202
C03DA01
ATC
spironolactone; oral
1.6
9.0
201
1296
R60.0
ICD-10 Finland
Localized oedema
1.7
9.0
181
1137
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
3.1
8.9
36
118
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.9
8.8
19
39
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
27.7
8.5
11
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
27.7
8.5
11
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
90.6
8.4
9
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
90.6
8.4
9
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
8.3
8
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
8.3
8
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
8.3
8
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
8.3
8
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
8.3
8
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
8.3
8
*
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
+∞
8.3
8
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
8.3
8
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
8.3
8
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
8.3
8
*
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
+∞
8.3
8
*
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
8.3
128
744
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
8.6
8.3
17
20
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.7
8.2
25
68
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.2
8.1
31
98
I82.0
ICD-10 Finland
Budd-Chiari syndrome
33.6
8.1
10
*
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
33.6
8.1
10
*
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
33.6
8.1
10
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
33.6
8.1
10
*
H02AB06
ATC
prednisolone; systemic
1.4
8.1
582
4752
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
8.0
122
707
K93
ICPC
Pulmonary embolism
3.9
8.0
23
60
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
4.7
7.9
18
39
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
7.9
111
629
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.2
7.8
30
95
A05AA02
ATC
ursodeoxycholic acid; oral
4.1
7.8
21
52
D73.1
ICD-10 Finland
Hypersplenism
45.2
7.7
9
*
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
45.2
7.7
9
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.7
417
3235
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
3.2
7.7
29
91
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.1
7.6
31
102
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
7.6
153
961
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
3.4
7.5
26
77
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.9
7.5
89
476
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.7
7.5
39
147
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.5
201
1353
A02BC02
ATC
pantoprazole; systemic
1.4
7.5
842
7362
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.7
7.5
23
63
B59
ICPC
Blood and Immunity, Other therap proced/minor surg NEC
80.5
7.4
8
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
80.5
7.4
8
*
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
2.5
7.4
44
178
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
3.8
7.4
22
59
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
7.3
253
1799
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.6
7.3
148
2260
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.6
7.3
23
64
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
7.3
7
*
D46.2
ICD-10 Finland
Refractory anaemia with excess of blasts [RAEB]
+∞
7.3
7
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
7.3
7
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
7.3
7
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
7.3
7
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
7.3
7
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
7.3
7
*
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
+∞
7.3
7
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
7.3
7
*
B01AC14
ATC
[U] anagrelide
+∞
7.3
7
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.3
7
*
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
9.4
7.3
14
15
S18
ICPC
Laceration/cut
1.4
7.2
567
4670
B03XA01
ATC
erythropoietin; parenteral
7.3
7.2
16
22
ZX070
NOMESCO Finland
Intensity modified radiotherapy
30.2
7.2
9
*
WX402
NOMESCO Finland
General anaesthesia
1.6
7.1
200
1360
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
7.1
139
865
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
7.1
69
345
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
7.1
335
2532
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
3.5
7.0
23
66
ZXE00
NOMESCO Finland
One hour or less
1.4
7.0
420
3307
TGC00
NOMESCO Finland
Bronchial lavation
2.7
7.0
35
130
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.9
117
701
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
2.2
6.8
55
255
KCD02
NOMESCO Finland
Transurethral resection of bladder
8.3
6.8
14
17
M10.9
ICD-10 Finland
Gout, unspecified
1.8
6.8
111
657
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.9
6.8
30
104
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.4
6.8
44
186
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
3.9
6.7
19
49
S77
ICPC
Malignant neoplasm of skin
22.6
6.7
9
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
22.6
6.7
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.6
493
4012
L29.8
ICD-10 Finland
Other pruritus
3.2
6.6
25
79
N17.8
ICD-10 Finland
Other acute renal failure
3.5
6.6
22
64
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
6.4
155
1016
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
70.2
6.4
7
*
GDC00
NOMESCO Finland
Lobectomy of lung
70.2
6.4
7
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
14.4
6.4
10
7
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.9
6.4
29
102
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.8
6.4
19
51
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.5
6.4
176
1192
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.9
6.3
72
381
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
2.8
6.3
31
114
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.3
6.3
23
71
E83.1
ICD-10 Finland
Disorders of iron metabolism
9.3
6.3
12
13
D69.1
ICD-10 Finland
Qualitative platelet defects
18.1
6.3
9
5
L02AE03
ATC
goserelin; implant
18.1
6.3
9
5
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.0
6.3
63
319
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
6.3
6
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
6.3
6
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
6.3
6
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
6.3
6
*
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
+∞
6.3
6
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
6.3
6
*
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
+∞
6.3
6
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
6.3
6
*
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
+∞
6.3
6
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
6.3
6
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
6.3
6
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
6.3
6
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
6.3
6
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
6.3
6
*
L02AE04
ATC
triptorelin; parenteral
+∞
6.3
6
*
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
6.3
6
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
26.8
6.2
8
*
PD4AD
NOMESCO Finland
CT of lower extremity arteries
3.7
6.2
19
52
N02AX02
ATC
tramadol; systemic, rectal
1.3
6.2
515
4250
GD1AD
NOMESCO Finland
Thorax CT examination
1.9
6.2
72
384
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.1
6.1
25
83
PFH63
NOMESCO Finland
Bypass from femoral or popliteal artery to distal posterior tibial artery
12.6
6.1
10
8
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
8.6
6.1
12
14
L53.9
ICD-10 Finland
Erythematous condition, unspecified
3.6
6.0
19
53
ZPB22
NOMESCO Finland
Autograft of vein
5.2
6.0
17
33
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.7
6.0
102
611
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
455
118
57.94
307.65
1.1
1.0
—
—
—
0
0
552
197
47.02
307.65
1.3
1.2
17.10
20.45
u/l
0.26
416
170
912
1153
22.74
307.65
11.9
2.1
291.07
234.21
u/l
19.86
899
1084
298
101
37.68
307.65
1.5
1.2
—
—
—
0
0
513
1126
6.77
240.01
3.8
2.0
87.01
67.83
e9/l
20.90
366
838
586
1461
6.36
239.49
4.2
2.0
1.97
1.78
%
4.52
535
1288
845
3045
5.82
222.88
5.6
2.5
360.24
359.69
umol/l
0.05
803
2604
1052
5041
6.10
183.85
20.4
5.7
21.32
26.52
%
44.11
1035
4738
1039
4971
5.89
180.61
19.6
5.6
65.16
58.32
%
53.74
1022
4700
1080
5448
6.11
172.52
18.5
5.5
0.09
0.04
e9/l
57.16
1001
4591
157
117
15.07
170.75
9.5
2.6
1.27
1.34
%
0.06
137
95
1082
5520
6.03
168.84
19.1
5.6
1.91
1.83
e9/l
0.23
1022
4768
1090
5611
6.10
167.72
20.6
5.7
0.25
0.20
e9/l
3.71
1023
4808
1101
5847
6.00
159.11
25.7
6.3
6.43
4.38
e9/l
27.65
1029
4962
500
1725
4.03
124.40
2.9
2.6
18.14
22.20
%
7.39
476
1594
1001
5584
4.15
118.15
11.6
3.9
13.01
12.09
umol/l
2.05
990
5238
175
252
7.84
118.13
3.0
2.2
3.17
3.47
g/l
1.81
167
234
517
1881
3.85
118.11
2.8
2.5
2.54
2.28
g/l
18.30
493
1723
534
2018
3.74
114.70
3.0
2.5
11.05
12.62
umol/l
4.61
512
1862
107
87
13.28
109.83
10.2
2.5
70.76
56.67
%
6.83
88
69
135
259
5.69
68.07
2.6
2.0
92.99
88.76
%
1.28
122
253
805
4893
2.62
63.12
4.0
3.0
110.62
130.30
ug/l
1.35
767
4501
197
581
3.80
57.71
1.9
1.5
0.98
1.55
g/l
17.15
173
510
124
263
5.09
55.69
1.8
1.5
—
—
—
0
0
904
6027
2.54
54.89
9.3
6.3
1.21
1.21
mmol/l
0.50
796
5179
1124
8437
3.09
52.08
19.0
5.8
88.65
77.71
u/l
10.12
1107
7856
755
4733
2.37
51.18
29.1
10.4
0.05
0.00
e9/l
3.93
665
3828
110
241
4.88
47.43
3.1
2.1
177.40
199.03
%
1.49
105
222
84
157
5.64
43.29
5.8
5.9
505.67
354.08
iu/ml
—
6
24
767
5093
2.19
41.97
6.7
3.9
35.63
35.43
g/l
0.44
738
4708
543
3167
2.20
41.12
2.5
2.4
7.55
2.83
mg/l
30.80
474
2689
784
5382
2.10
37.69
8.8
5.8
1.22
1.21
mmol/l
1.22
735
4883
35
26
13.80
37.47
7.0
3.0
1.06
1.02
%
0.04
35
26
263
1164
2.57
37.16
5.4
2.2
7.66
7.67
umol/l
0.01
239
1018
427
2379
2.17
35.20
2.1
1.7
1.15
1.38
mg/l
1.06
335
1873
341
1823
2.17
30.60
3.7
2.5
0.82
0.82
mmol/l
0.47
325
1678
305
1568
2.22
30.13
5.5
5.1
1.07
1.02
mmol/l
2.01
291
1433
909
6927
1.98
28.76
6.6
4.9
6.67
6.86
mmol/l
2.21
888
6590
338
1840
2.12
28.71
3.0
1.9
32.64
29.71
s
8.54
320
1781
443
2672
1.98
28.31
6.2
3.7
77.17
85.30
%
8.56
423
2608
153
618
2.67
25.55
2.7
1.4
17.38
2.72
ug/l
0.53
124
457
37
51
7.43
25.53
1.1
1.3
—
—
—
0
0
37
51
7.43
25.53
1.1
1.3
—
—
—
0
0
215
1022
2.32
25.27
2.7
1.6
66.30
66.79
g/l
0.40
204
922
167
709
2.55
25.19
2.4
2.3
10.88
11.01
g/l
0.10
154
653
115
406
3.00
24.69
2.5
1.5
33.70
34.78
mg/l
0.10
102
341
771
5728
1.82
24.51
27.4
18.6
1.45
1.35
inr
4.93
661
4814
114
407
2.97
23.98
2.5
1.5
69.46
43.15
mg/l
0.42
100
342
193
905
2.32
23.32
2.0
2.0
0.20
0.20
g/l
0.86
182
823
139
568
2.62
22.61
1.8
1.4
1.58
1.20
g/l
1.24
130
519
61
157
4.02
21.33
2.0
1.5
—
—
—
0
0
25
5
50.88
21.17
1.1
1.0
—
—
—
0
0
77
243
3.30
19.94
2.0
1.4
—
—
—
0
0
350
2154
1.85
19.85
2.2
1.9
—
—
—
0
0
98
357
2.88
19.85
2.5
1.4
11.33
1.39
ratio
0.77
61
209
116
489
2.50
17.62
2.3
1.7
1.13
1.65
ug/l
0.53
100
426
203
1087
2.02
17.26
6.6
6.4
10.29
10.87
mmol/l
0.55
193
1028
72
239
3.13
17.17
1.9
1.4
—
—
—
0
0
538
3884
1.64
16.63
2.0
1.7
18.68
20.37
nmol/l
1.83
489
3215
632
4774
1.61
16.10
4.8
2.5
—
—
estimate
—
0
0
990
8386
1.70
15.56
5.6
4.5
8.64
12.80
mm/h
19.75
949
7788
730
5801
1.57
14.34
2.5
2.2
87.19
94.70
pmol/l
5.09
487
2969
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
87
359
2.52
13.82
4.6
2.6
0.37
0.36
iu/ml
0.05
55
204
156
825
2.01
13.61
2.2
1.6
—
—
—
0
0
364
2485
1.64
13.48
5.2
2.1
—
—
—
0
0
22
35
6.37
13.30
2.5
1.1
—
—
—
0
0
22
35
6.37
13.30
2.5
1.1
—
—
—
0
0
22
35
6.37
13.30
2.5
1.1
—
—
—
0
0
22
35
6.37
13.30
2.5
1.1
—
—
—
0
0
67
251
2.76
12.91
1.2
1.3
—
—
—
0
0
111
526
2.21
12.90
2.5
1.4
6.61
7.55
g/l
7.95
103
463
111
526
2.21
12.90
2.5
1.4
4.31
4.24
g/l
0.26
103
464
111
526
2.21
12.90
2.5
1.4
3.43
3.71
g/l
1.36
102
464
570
4355
1.54
12.87
3.7
3.3
2003.84
1551.63
ng/l
1.43
510
3784
104
484
2.25
12.63
2.5
1.4
3.06
2.96
g/l
0.44
95
422
54
182
3.05
12.59
1.4
1.3
—
—
—
0
0
35
89
4.01
12.50
2.3
1.3
—
—
—
0
0
161
888
1.92
12.41
3.2
3.2
1.21
1.23
mmol/l
2.16
133
739
60
218
2.83
12.25
1.5
1.3
—
—
—
0
0
16
6
26.96
12.06
4.6
1.0
44.26
15.73
u/ml
—
16
6
482
3604
1.53
11.74
3.1
2.4
52.68
61.18
u/l
4.11
446
3305
464
3443
1.53
11.70
4.8
2.6
32.39
33.86
u/l
0.42
438
3217
499
3789
1.51
11.16
3.9
3.4
36.92
81.14
e6/l
1.19
393
2908
35
98
3.64
10.95
2.3
1.3
—
—
—
0
0
41
129
3.25
10.74
1.1
1.1
—
—
—
0
0
96
466
2.14
10.52
2.6
1.4
10.47
10.45
g/l
0.01
87
401
504
3878
1.48
10.37
3.5
2.1
2.34
2.36
mmol/l
2.24
461
3376
81
370
2.27
10.30
2.6
1.4
0.00
0.00
g/l
0.50
73
337
92
443
2.16
10.29
2.6
1.4
0.99
0.48
g/l
0.80
79
379
15
8
18.94
10.27
1.1
1.1
—
—
—
0
0
23
49
4.76
10.26
1.6
2.8
1152.17
1002.80
u/ml
0.14
23
49
95
464
2.13
10.25
2.3
1.7
—
—
—
0
0
41
134
3.12
10.11
1.2
1.2
3.61
3.20
u/ml
0.08
18
46
29
76
3.88
9.97
2.3
1.2
—
—
—
0
0
29
76
3.88
9.97
2.3
1.2
—
—
—
0
0
29
76
3.88
9.97
2.3
1.2
—
—
—
0
0
78
357
2.26
9.88
2.6
1.4
0.00
0.00
g/l
-0.00
69
320
75
342
2.26
9.59
2.7
1.4
0.00
0.00
g/l
-0.00
69
319
166
1000
1.75
9.57
2.1
1.8
433.87
373.43
nmol/l
2.29
157
902
796
6747
1.44
9.52
4.2
3.2
61.09
49.69
u/l
2.72
762
6216
248
1665
1.60
9.46
2.0
1.8
—
—
—
0
0
278
1925
1.56
9.27
1.6
1.3
2.56
2.66
g/l
0.35
186
1094
30
85
3.59
9.25
1.4
1.1
—
—
—
0
0
49
188
2.67
9.08
1.4
1.3
—
—
—
0
0
87
434
2.07
8.90
1.9
1.7
—
—
—
0
0
19
24
8.01
8.86
1.5
1.1
64.45
82.60
%
—
11
10
19
24
8.01
8.86
1.5
1.1
62.36
81.10
%
—
11
10
140
824
1.78
8.73
4.4
3.6
5.25
5.19
kpa
0.31
129
783
38
130
2.98
8.70
1.2
1.2
3.14
6.80
u/ml
0.64
22
65
424
3242
1.45
8.66
3.8
3.3
0.56
0.41
e6/l
0.39
327
2396
40
142
2.87
8.59
1.5
1.3
160.56
156.55
au/ml
—
9
50
141
837
1.77
8.54
1.7
1.7
—
—
—
0
0
1159
10686
1.64
8.49
32.8
15.8
20.08
25.35
mg/l
9.02
1049
8784
12
6
20.16
8.47
1.4
3.3
—
—
—
0
0
57
244
2.40
8.45
2.2
1.9
143.32
33.87
u/ml
0.69
45
196
42
155
2.77
8.40
1.4
1.3
—
—
—
0
0
35
117
3.04
8.35
1.6
1.5
—
—
—
0
0
357
2663
1.46
8.23
3.1
2.6
3.78
5.47
e6/l
3.02
329
2422
121
696
1.81
8.15
4.1
3.4
2.40
1.91
mmol/l
0.55
83
498
36
125
2.93
8.05
1.3
1.3
—
—
—
0
0
17
22
7.81
7.88
2.9
1.1
—
—
—
0
0
17
22
7.81
7.88
2.9
1.1
—
—
—
0
0
17
22
7.81
7.88
2.9
1.1
—
—
—
0
0
26
75
3.52
7.84
1.8
1.7
—
—
—
0
0
397
3053
1.43
7.69
4.1
3.5
0.02
0.01
estimate
0.26
180
907
151
941
1.68
7.68
3.6
2.5
53.15
63.89
ml/min/173m2
4.59
99
395
19
45
4.27
7.49
2.6
1.9
2.14
3.44
nmol/l
1.41
19
45
40
155
2.63
7.32
1.2
1.2
350.95
256.73
u/ml
0.74
22
76
44
180
2.49
7.22
1.2
1.3
—
—
—
0
0
223
1550
1.53
7.18
2.1
1.9
—
—
—
0
0
17
27
6.36
6.94
1.4
1.5
—
—
—
0
0
41
167
2.50
6.81
1.4
1.2
—
17.62
—
0
5
33
122
2.75
6.63
1.6
1.5
—
—
—
0
0
591
4947
1.35
6.59
5.1
4.3
52.06
71.64
ng/l
0.40
478
3774
89
498
1.84
6.58
2.5
2.2
233.75
892.60
ug/l
0.98
84
471
621
5241
1.35
6.54
2.7
2.5
76.86
79.25
nmol/l
1.30
571
4587
173
1171
1.55
6.26
4.3
3.4
—
—
—
0
0
28
99
2.87
6.12
1.1
1.1
89.64
96.80
%
0.62
28
91
838
7438
1.34
6.07
5.8
5.0
47.45
2544.61
e6/l
2.58
11
112
316
2430
1.39
5.90
1.8
1.8
1013.42
1168.35
nmol/l
2.42
250
1837
10
9
11.18
5.80
1.2
1.1
—
—
—
0
0
692
6005
1.32
5.72
4.7
4.1
0.00
0.00
estimate
-0.00
200
1181
701
6098
1.31
5.67
4.7
4.1
6.44
1.43
estimate
0.35
209
1225
704
6131
1.31
5.64
4.7
4.1
0.02
0.02
estimate
0.07
196
1137
16
32
5.05
5.57
39.2
29.1
131.75
145.17
ug/l
0.30
16
23
70
386
1.86
5.46
1.4
1.3
—
—
—
0
0
418
3396
1.34
5.44
4.4
4.2
0.00
0.00
estimate
0.50
182
1077
203
1469
1.45
5.30
7.9
7.3
0.70
1.05
mmol/l
0.46
159
1215
204
1478
1.45
5.29
7.7
7.4
4.97
5.09
kpa
0.90
195
1422
204
1478
1.45
5.29
7.7
7.4
10.79
11.30
kpa
0.92
195
1423
93
565
1.69
5.24
2.7
3.1
4.34
4.43
pmol/l
0.51
82
493
310
2428
1.36
5.10
3.2
2.2
2.44
2.45
mmol/l
0.92
283
2131
15
40
3.78
5.10
1.2
1.2
—
—
—
0
0
15
32
4.73
4.99
2.3
2.9
—
—
—
0
0
16
37
4.36
4.94
4.0
1.9
3146.64
438.52
e6/l
0.45
11
31
113
733
1.59
4.93
8.0
8.9
23.96
24.22
mmol/l
0.32
113
718
939
8597
1.31
4.77
48.5
19.3
16.70
13.68
%
138.32
933
8440
144
995
1.50
4.74
3.4
3.7
84.68
94.20
ng/l
0.77
126
847
43
211
2.07
4.72
1.4
1.5
—
—
—
0
0
1103
10347
1.38
4.68
33.0
15.5
73.20
74.53
ml/min/173m2
1.44
1060
9605
1093
10242
1.37
4.64
5.7
4.7
1.33
1.29
mmol/l
1.20
1043
9274
32
141
2.30
4.57
1.1
1.3
0.19
0.20
nmol/l
0.34
25
120
27
110
2.48
4.56
1.2
1.5
16700.77
93605.18
e6/l
0.62
13
57
68
394
1.76
4.56
2.8
3.0
—
—
—
0
0
180
1314
1.43
4.47
8.3
7.6
94.02
94.96
%
0.70
175
1272
16
49
3.29
4.47
1.3
1.3
—
—
—
0
0
48
251
1.95
4.44
1.4
1.3
—
—
—
0
0
57
318
1.83
4.34
1.5
1.6
1.11
0.12
iu/ml
—
9
65
24
96
2.53
4.23
1.1
1.1
—
—
—
0
0
12
26
4.65
4.06
2.0
2.5
0.63
0.61
mmol/l
0.85
12
26
182
1355
1.40
4.05
4.1
3.1
1.47
1.96
mmol/l
1.16
152
1184
7
7
10.04
4.01
1.0
1.9
—
—
—
0
0
11
22
5.03
4.00
1.3
1.1
—
—
—
0
0
20
75
2.69
4.00
1.5
1.4
—
—
—
0
0
25
105
2.41
3.99
2.6
2.9
—
—
—
0
0
524
4528
1.26
3.98
4.7
4.1
0.02
0.02
estimate
0.15
182
953
45
240
1.91
3.96
2.4
2.8
30.40
35.77
umol/l
1.01
40
216
8
11
7.31
3.86
1.0
1.2
—
—
—
0
0
16
54
2.99
3.85
1.3
1.3
—
—
—
0
0
31
146
2.15
3.82
1.1
1.5
32.67
26.71
g/l
1.83
26
128
56
324
1.76
3.82
2.8
3.5
4.21
1.80
index
0.29
39
154
17
60
2.86
3.80
1.3
1.3
—
—
—
0
0
50
281
1.81
3.76
1.7
1.6
—
—
—
0
0
11
24
4.61
3.74
1.1
1.5
14.09
10.47
g/l
0.61
11
14
34
168
2.05
3.72
1.1
1.3
0.76
11.31
nmol/l
0.49
34
160
46
253
1.85
3.71
1.3
1.6
—
—
—
0
0
624
5531
1.24
3.70
2.6
2.5
—
—
—
0
0
15
50
3.02
3.69
1.9
1.4
10.91
9.10
ug/l
0.16
15
43
140
1012
1.43
3.69
2.3
2.2
33.82
42.04
u/l
0.81
117
812
72
452
1.63
3.65
2.1
2.0
39.84
39.26
u/l
0.08
63
386
28
129
2.20
3.65
1.1
1.5
2383.06
1562.94
e6/l
0.34
16
90
69
430
1.64
3.61
4.9
3.9
24.48
24.85
mmol/l
0.44
61
384
15
51
2.96
3.58
1.0
1.1
—
—
—
0
0
48
271
1.80
3.57
2.3
2.2
13.97
12.41
mg/l
0.52
43
251
478
4137
1.24
3.47
2.3
2.2
140.74
228.56
u/l
2.62
446
3902
7
11
6.39
3.18
1.1
1.2
—
—
—
0
0
64
407
1.60
3.12
1.2
1.2
0.16
0.49
u/ml
—
5
31
12
35
3.45
3.11
1.1
1.3
—
—
—
0
0
6
8
7.53
3.05
1.0
1.4
—
—
—
0
0
232
1869
1.29
3.05
3.8
3.1
1.41
2.61
e6/l
2.99
120
910
10
26
3.87
2.98
1.1
1.1
—
—
—
0
0
308
2576
1.25
2.97
3.8
4.4
192.49
445.39
ng/l
2.14
243
2194
27
134
2.04
2.97
2.1
1.2
—
—
—
0
0
8
17
4.73
2.92
1.8
1.0
—
—
—
0
0
8
18
4.46
2.79
1.6
1.0
—
—
—
0
0
41
240
1.73
2.76
1.4
1.2
96.00
341.82
titre
—
5
22
250
2061
1.26
2.72
3.7
3.0
0.82
1.45
e6/l
1.77
138
1112
907
8494
1.21
2.71
4.6
4.2
15.14
15.02
pmol/l
0.69
847
7686
26
134
1.96
2.61
2.2
1.2
—
—
—
0
0
26
134
1.96
2.61
1.1
1.1
1.49
1.55
g/l
0.29
26
119
88
627
1.43
2.57
1.8
1.5
—
—
—
0
0
12
42
2.87
2.55
1.6
1.2
—
—
—
0
0
12
42
2.87
2.55
1.6
1.2
—
—
—
0
0
364
3147
1.22
2.54
3.7
3.2
0.00
0.05
1.02
12
104
1063
10152
1.23
2.42
6.0
5.4
2.16
2.00
mu/l
2.69
1022
9265
13
52
2.51
2.36
1.3
1.1
—
—
—
0
0
25
133
1.90
2.32
2.2
1.2
—
—
—
0
0
6
13
4.63
2.27
2.2
2.2
4.50
5.69
ug/l
—
6
13
14
60
2.35
2.22
1.1
1.2
96.21
78.28
u/l
0.45
14
53
1166
11278
1.26
2.19
35.9
20.1
139.44
139.79
mmol/l
4.92
1156
11041
1108
10658
1.23
2.18
6.6
5.5
1.26
1.45
mmol/l
45.45
1065
9754
15
67
2.25
2.18
1.5
1.3
—
—
—
0
0
14
61
2.31
2.15
1.1
1.2
31.57
22.88
u/l
0.30
14
52
17
81
2.11
2.13
1.0
1.0
—
—
—
0
0
1115
10740
1.23
2.12
6.7
5.6
3.98
4.48
mmol/l
56.15
1078
9910
47
308
1.55
2.11
2.0
2.1
137.43
130.16
g/l
0.76
37
249
21
111
1.91
2.01
1.1
1.1
—
—
—
0
0
102
783
1.33
1.95
9.8
9.2
0.64
0.64
%
0.02
102
778
1165
11295
1.24
1.95
38.0
20.2
4.04
4.00
mmol/l
5.26
1154
11039
6
16
3.76
1.93
2.0
1.3
—
—
—
0
0
65
465
1.42
1.92
1.4
1.9
3.07
7.10
iu/ml
1.48
12
102
23
128
1.81
1.90
2.3
1.2
—
—
—
0
0
14
65
2.17
1.88
1.5
1.3
—
—
—
0
0
21
116
1.82
1.79
1.2
1.1
—
—
—
0
0
29
177
1.65
1.77
1.0
1.2
—
1.48
—
0
5
112
886
1.29
1.75
3.1
2.7
131.21
130.09
g/l
0.17
107
859
1163
11308
1.22
1.67
28.9
10.9
25.16
25.34
u/l
0.16
1149
10868
86
663
1.32
1.64
3.9
3.6
1.02
1.02
ratio
0.16
81
613
12
56
2.15
1.61
2.3
2.0
17.31
17.72
nmol/l
0.09
12
46
22
128
1.73
1.61
2.3
1.2
—
—
—
0
0
13
63
2.07
1.60
1.1
1.0
—
—
—
0
0
14
70
2.01
1.59
1.9
2.3
—
—
—
0
0
22
129
1.72
1.57
2.3
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
44
2.28
1.55
1.3
1.2
—
—
—
0
0
142
1176
1.23
1.53
3.8
3.3
257.42
233.99
ng/l
0.22
132
1075
5
15
3.34
1.52
1.0
1.0
70.40
91.73
titre
—
5
15
102
815
1.27
1.50
9.9
8.9
1.47
1.31
%
1.25
102
809
149
1251
1.22
1.42
1.3
1.4
—
—
—
0
0
46
330
1.41
1.40
1.1
1.2
—
48.83
—
0
20
837
8750
0.88
1.39
52.8
21.0
320.67
331.99
g/l
55.35
830
8698
25
158
1.59
1.38
1.0
1.1
—
4.37
—
0
8
45
323
1.41
1.37
1.8
1.2
—
—
—
0
0
100
808
1.26
1.36
3.5
2.3
13.72
14.87
nmol/l
0.72
91
736
16
90
1.79
1.33
1.0
1.1
—
—
—
0
0
23
147
1.57
1.23
1.7
2.6
13.75
20.87
mg/l
—
8
46
1124
10957
1.16
1.23
7.4
6.5
2.23
2.58
mmol/l
41.68
1085
10074
12
63
1.91
1.23
1.3
7.1
—
69.56
—
0
18
1088
10586
1.15
1.20
7.8
7.4
38.27
40.41
mmol/mol
13.94
1051
9828
13
225
0.57
1.19
1.0
1.2
1.49
1.52
g/l
0.15
13
225
12
65
1.85
1.13
1.0
1.1
284.17
239.17
mg/l
0.70
12
59
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
10
52
1.93
1.06
2.4
3.7
1.20
1.00
index
—
10
52
54
419
1.30
1.06
2.0
1.6
0.43
0.36
mg/l
0.32
25
184
464
4331
1.11
1.04
5.0
4.3
2.03
2.03
ug/l
0.01
420
3897
5
22
2.28
1.03
1.2
1.9
—
—
—
0
0
5
22
2.28
1.03
1.4
1.5
—
—
—
0
0
121
1033
1.19
1.02
1.7
1.8
1.49
1.55
%
0.51
104
877
47
360
1.32
1.01
4.5
3.6
0.77
0.82
nmol/l
0.30
35
298
88
729
1.22
1.01
3.1
2.4
1.33
1.15
%
1.43
88
724
12
68
1.77
1.00
1.1
1.1
43.12
32.55
mg/l
0.80
12
60
9
48
1.88
1.00
2.6
1.5
—
—
—
0
0
9
48
1.88
1.00
1.1
1.1
—
—
—
0
0
11
61
1.81
0.98
1.0
1.0
—
—
—
0
0
32
232
1.39
0.98
1.1
1.2
—
60.53
—
0
24
0
29
0.00
0.97
0.0
2.1
—
8.69
—
0
14
9
52
1.74
0.92
3.1
2.4
58.44
48.12
umol/l
—
9
44
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
21
144
1.47
0.87
1.8
1.3
—
—
—
0
0
63
767
0.81
0.86
2.1
2.1
3.51
3.52
ratio
0.00
44
633
1170
11503
1.14
0.83
45.2
21.2
84.81
81.70
umol/l
2.09
1162
11335
13
81
1.61
0.81
1.1
1.1
—
—
—
0
0
14
89
1.58
0.81
1.1
1.0
301.29
282.68
mg/l
0.52
14
81
169
1519
1.13
0.76
5.3
5.5
31.41
32.97
%
1.34
136
976
141
1253
1.14
0.75
2.1
2.5
4.67
7.84
ug/l
2.65
106
1110
1095
10741
1.11
0.74
6.1
5.7
6.04
6.09
mmol/l
0.65
1035
9736
249
2292
1.11
0.73
1.3
1.3
0.66
1.44
u/ml
2.61
51
618
7
38
1.85
0.73
1.0
2.6
45.81
228.19
ug/l
—
7
33
9
55
1.64
0.73
2.1
1.5
2.44
2.98
u/field
—
9
42
7
39
1.80
0.72
6.1
2.8
4.70
5.01
kpa
—
7
39
7
39
1.80
0.72
6.1
2.8
11.10
9.82
kpa
—
7
39
13
84
1.55
0.72
1.1
1.1
—
—
—
0
0
13
84
1.55
0.72
1.1
1.1
—
—
—
0
0
12
76
1.58
0.71
1.8
1.7
105.58
103.39
ng/l
0.04
12
76
33
257
1.29
0.69
1.1
1.3
1.62
43.25
e6/l
1.09
16
199
10
61
1.64
0.68
1.3
2.3
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
—
—
—
0
0
41
329
1.25
0.68
1.5
1.4
290.63
299.55
ug/g
0.09
24
200
19
136
1.40
0.67
2.8
4.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.3
—
—
—
0
0
33
259
1.28
0.66
1.2
1.4
71.95
677.71
e6/l
0.80
19
209
18
128
1.41
0.65
1.1
1.1
—
73.91
—
0
11
5
29
1.73
0.64
1.8
1.7
111.20
59.72
nmol/24h
—
5
29
34
270
1.27
0.62
2.1
1.9
178.79
208.81
pmol/l
1.07
34
256
5
30
1.67
0.61
6.8
7.5
7.16
5.41
kpa
—
5
30
42
345
1.22
0.59
1.3
1.3
—
—
—
0
0
22
166
1.33
0.58
1.2
1.2
176.43
199.53
miu/ml
—
7
66
8
54
1.48
0.57
1.1
1.4
—
—
—
0
0
13
90
1.45
0.55
1.1
1.1
—
—
—
0
0
104
929
1.13
0.55
1.4
1.5
—
—
—
0
0
265
2818
0.93
0.53
5.0
4.3
1.02
1.02
kg/l
1.19
193
1840
9
63
1.43
0.52
1.4
1.3
144.83
165.37
pmol/l
—
9
63
40
477
0.83
0.51
1.6
1.7
—
—
—
0
0
438
4569
0.94
0.51
3.5
3.4
6.96
7.25
mmol/l
0.72
367
3849
47
552
0.85
0.50
1.7
1.8
3.31
3.48
mmol/l
0.44
29
419
120
1089
1.11
0.50
1.4
1.4
—
—
—
0
0
75
661
1.14
0.50
1.4
1.3
112.57
259.17
u/ml
1.96
69
616
14
102
1.38
0.47
1.1
1.1
—
—
—
0
0
82
732
1.13
0.46
2.5
2.6
22.68
17.31
au/ml
—
9
50
130
1192
1.10
0.46
2.8
2.2
152.20
162.63
ug/g
0.13
108
954
1173
11608
1.09
0.43
59.8
23.8
91.05
91.61
fl
0.87
1166
11432
1173
11609
1.08
0.43
60.1
23.9
371.48
242.47
e9/l
105.54
1156
11306
5
31
1.62
0.43
1.6
1.3
14.54
14.69
pmol/l
—
5
23
1173
11611
1.08
0.42
60.1
23.9
10.13
6.80
e9/l
27.79
1153
11258
1173
11611
1.08
0.42
60.6
24.3
42.16
40.25
%
24.64
1166
11433
1173
11611
1.08
0.42
60.0
23.9
4.79
4.47
e12/l
25.86
1152
11255
5
32
1.56
0.42
1.6
1.1
—
—
—
0
0
1173
11613
1.08
0.41
60.5
24.0
134.94
135.23
g/l
0.21
1166
11440
37
314
1.18
0.41
1.6
1.7
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
0.91
—
0
8
0
16
0.00
0.41
0.0
1.3
—
1.22
—
0
8
0
16
0.00
0.41
0.0
1.3
—
0.93
—
0
8
11
79
1.40
0.40
1.1
1.1
—
—
—
0
0
5
34
1.47
0.40
1.4
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
47.06
—
0
13
9
66
1.37
0.38
1.1
1.2
—
—
—
0
0
9
66
1.37
0.38
1.1
1.2
—
—
—
0
0
493
4775
1.05
0.38
2.0
2.0
1.48
1.32
mmol/l
3.15
436
3960
5
36
1.39
0.38
1.6
1.1
—
—
—
0
0
9
70
1.29
0.36
1.0
1.8
9.79
14.04
umol/l
—
9
62
35
300
1.17
0.36
1.3
1.1
—
—
—
0
0
51
451
1.14
0.35
1.0
1.1
—
—
—
0
0
35
303
1.16
0.33
1.3
1.1
—
—
—
0
0
6
86
0.70
0.33
1.5
1.2
0.57
1.45
u/ml
—
6
55
19
230
0.82
0.31
1.4
1.5
—
—
—
0
0
288
2767
1.05
0.31
1.7
1.8
47982602.95
22677177.57
pmol/l
0.22
223
2249
146
1550
0.93
0.31
9.0
7.1
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
29
251
1.16
0.28
1.4
2.1
3.54
25.74
iu/l
0.51
11
106
39
434
0.90
0.24
1.6
1.6
—
—
—
0
0
9
76
1.19
0.24
1.2
1.1
8.59
9.37
mmol/l
—
9
69
21
180
1.17
0.23
1.5
1.4
—
—
—
0
0
196
1886
1.05
0.22
1.2
1.3
6.97
13.07
u/ml
0.94
76
694
13
107
1.22
0.21
2.4
2.4
660.50
589.01
ml
—
8
72
0
11
0.00
0.21
0.0
1.6
—
22.62
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
13
156
0.83
0.21
1.3
1.4
—
—
—
0
0
8
104
0.77
0.21
1.3
1.5
—
268.57
—
0
14
5
43
1.16
0.21
1.4
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
6
50
1.20
0.19
2.5
1.1
4.82
4.93
umol/l
—
6
27
359
3506
1.03
0.19
4.0
4.0
21.30
24.11
%
3.16
160
1687
21
239
0.88
0.19
1.2
1.2
0.85
0.89
g/l
0.45
21
239
6
51
1.18
0.19
1.2
1.1
221.90
231.10
iu/ml
—
6
51
6
52
1.15
0.19
1.7
1.2
41.32
38.43
g/l
—
6
52
28
251
1.12
0.18
1.7
1.4
—
—
—
0
0
28
251
1.12
0.18
1.7
1.4
—
—
—
0
0
13
109
1.19
0.18
1.2
1.3
—
—
—
0
0
36
330
1.09
0.17
2.6
2.3
216.76
91.97
ug/min
0.46
21
200
13
152
0.85
0.17
2.6
2.0
—
—
—
0
0
15
173
0.87
0.16
2.5
2.0
—
—
—
0
0
44
417
1.06
0.10
1.3
1.2
—
—
—
0
0
452
4572
0.98
0.10
4.3
4.2
15.90
7.97
mg/mmol
1.49
296
2850
5
48
1.04
0.09
1.0
1.1
—
58.67
—
0
6
247
2510
0.98
0.09
2.9
2.9
0.76
0.73
ug/l
0.12
169
1662
19
175
1.09
0.08
2.3
1.7
267.53
273.76
mu/l
0.05
19
162
6
72
0.83
0.07
1.0
1.6
103.17
85.46
umol/l
—
6
72
9
87
1.03
0.07
1.0
1.2
84.44
106.77
pmol/l
—
9
87
61
591
1.03
0.06
1.2
1.2
117.30
121.14
u/ml
0.03
20
232
34
327
1.04
0.05
1.5
1.5
16376.70
13161.08
e6/l
0.20
23
231
200
1983
1.01
0.03
1.3
1.3
21.70
34.90
iu/ml
2.13
67
608
11
116
0.95
0.00
1.1
1.6
—
24.95
—
0
22
6
60
1.00
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
51.58
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
87
0.92
-0.00
1.4
1.3
2.10
2.15
mmol/l
—
8
80
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
12.00
—
0
7
7
69
1.01
-0.00
2.3
2.0
—
130.16
—
0
19
27
270
1.00
-0.00
6.4
3.5
21.64
28.30
mg/l
0.58
18
191
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint POLYCYTVERA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLYCYTVERA | 2.079 [1.84, 2.35] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.027 |
During the follow-up period (1.1.1998 — 31.12.2019), 1275 out of 3089 females with POLYCYTVERA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| POLYCYTVERA | 1.913 [1.67, 2.19] | < 0.001 |
| Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1129 out of 2970 males with POLYCYTVERA died.
Mortality risk
Mortality risk for people of age
years, who have POLYCYTVERA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.135% | 0.366% |
| 5 | 0.975% | 2.055% |
| 10 | 2.376% | 5.434% |
| 15 | 4.47% | 10.324% |
| 20 | 8.094% | 16.756% |
Relationships between endpoints
↥Index endpoint: POLYCYTVERA – Polycythaemia vera
GWS hits: 14
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data