hematologic disease: A disease involving the hematopoietic system.
Other and unspecified diseases of blood and blood-forming organs
DOID EFO Endpoint Browser PheWeb
D3_BLOODNAS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1265 |
4. Check minimum number of eventsNone |
1265 |
5. Include endpointsNone |
1265 |
6. Filter based on genotype QC (FinnGen only) |
1001 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified diseases of blood and blood-forming organs
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6321 | 3318 | 2939 |
| Only index persons | 5103 | 2725 | 2378 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.10 | 0.08 |
| Only index persons | 0.10 | 0.10 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 59.07 | 58.15 | 60.11 |
| Only index persons | 57.37 | 55.93 | 59.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1001 | 535 | 466 |
| Unadjusted period prevalence (%) | 0.20 | 0.19 | 0.21 |
| Median age at first event (years) | 60.58 | 58.53 | 62.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1031
- Matched controls
- 10310
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L01XX05
ATC
hydroxycarbamide; oral
56.1
322.3
185
40
XW000
NOMESCO Finland
Bone marrow biopsy
36.0
307.7
382
166
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
23.2
307.7
312
189
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
4503599627370496.0
307.7
810
*
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
117.9
307.7
168
17
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
75.9
307.7
197
32
D45
ICD-10 Finland
Polycythaemia vera
36.8
163.4
103
31
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
901.6
161.1
154
*
D75.2
ICD-10 Finland
Essential thrombocytosis
733.8
133.8
129
*
TPH00
NOMESCO Finland
Phlebotomy
42.1
85.9
52
13
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
127.1
77.1
82
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
73.3
263
822
SPAT1074
SPAT
Venesection
33.6
65.3
42
13
D75.1
ICD-10 Finland
Secondary polycythaemia
189.7
52.4
54
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.5
44.2
170
544
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
117.5
42.1
45
*
Z2221
NOMESCO Finland
Medical doctor
2.5
41.3
370
1872
28998
ICD-8 Finland
Other disease of blood and blood-forming organs, Alii definiti
+∞
38.8
37
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
37.3
604
3910
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.1
37.3
51
66
28999
ICD-8 Finland
Other disease of blood and blood-forming organs, Other and unspecified
+∞
35.6
34
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
34.9
172
636
C90.0
ICD-10 Finland
Multiple myeloma
10.4
34.7
39
39
WW500
NOMESCO Finland
Blood transfusion
4.7
33.5
82
188
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
72.2
31.1
35
5
R4110
NOMESCO Finland
Physiotherapy
2.2
30.5
362
2021
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
39.4
30.4
38
10
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
8.2
28.3
38
48
D70.89
ICD-10 Finland
Neutropenic splenomegaly
77.3
26.9
30
*
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
99.4
26.8
29
*
D75.0
ICD-10 Finland
Familial erythrocytosis
256.1
24.8
25
*
ZXE00
NOMESCO Finland
One hour or less
2.0
24.2
443
2848
Z3226
NOMESCO Finland
Physiotherapist
2.2
23.5
229
1162
ZX120
NOMESCO Finland
Intravenous
2.7
23.0
133
531
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
21.5
222
1150
M04AA01
ATC
allopurinol; systemic
2.4
21.4
175
822
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
21.4
151
664
D64.8
ICD-10 Finland
Other specified anaemias
5.8
21.3
39
69
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
21.0
201
1008
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
22.9
20.5
29
13
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
19.9
347
2163
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
75.0
19.8
22
*
L01XX35
ATC
anagrelide; oral
203.8
19.6
20
*
WW200
NOMESCO Finland
Immunization
4.6
18.6
45
102
B99
ICPC
Blood/lymph/spleen disease other
30.7
18.4
24
8
L03AA02
ATC
filgrastim; parenteral
4.2
18.4
49
120
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
18.0
18.3
28
16
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
18.2
417
2815
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
17.8
266
1567
WX402
NOMESCO Finland
General anaesthesia
1.9
17.6
259
1516
B03XA01
ATC
erythropoietin; parenteral
7.5
17.4
25
34
TPH00, ,
SPAT
42.8
17.3
21
5
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
17.2
400
2700
L03AB05
ATC
interferon alfa-2b; parenteral
32.1
17.1
22
7
Z3231
NOMESCO Finland
Registered nurse
1.9
17.0
304
1892
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
16.9
110
464
H02AB06
ATC
prednisolone; systemic
1.7
16.8
513
3735
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
12.9
16.7
29
23
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
12.4
16.4
29
24
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
16.1
73
255
B01AB05
ATC
enoxaparin; parenteral
1.8
15.8
351
2325
189
Kela drug reimbursment
Imatinib
61.0
15.8
18
*
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
86.4
15.6
17
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
15.2
141
693
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
15.2
224
1306
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
6.9
14.9
23
34
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
16.8
14.8
23
14
174
Kela drug reimbursment
Ruxolitinib
81.3
14.6
16
*
B74
ICPC
Malignant neoplasm blood other
81.3
14.6
16
*
374
Kela drug reimbursment
Ruxolitinib
81.3
14.6
16
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
14.3
253
1559
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
13.9
84
341
C03CA01
ATC
furosemide; systemic
1.7
13.7
333
2243
A02BC02
ATC
pantoprazole; systemic
1.7
13.6
721
5940
L01EJ01
ATC
ruxolitinib; oral
76.2
13.6
15
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.5
13.6
47
139
316
Kela drug reimbursment
Imatinib
141.8
13.5
14
*
R50.9
ICD-10 Finland
Fever, unspecified
2.0
13.3
171
949
WX002
NOMESCO Finland
Sedation and analgesia
1.8
13.2
221
1334
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
13.1
138
712
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
22.9
12.9
18
8
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
12.8
367
2574
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
12.7
79
326
WX892
NOMESCO Finland
Monitored bed care
2.3
12.6
97
440
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.7
12.6
39
107
2898X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Other specified diseases of blood and blood-forming organs
+∞
12.5
12
*
212
Kela drug reimbursment
Gout
4.4
12.5
31
72
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
12.4
179
1030
L01EA01
ATC
imatinib; oral
38.0
12.2
15
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.5
12.0
80
341
R11
ICD-10 Finland
Nausea and vomiting
2.2
11.8
105
506
UJF92
NOMESCO Finland
Capsular endoscopy
4.0
11.8
33
84
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
11.7
215
1331
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.8
11.7
26
55
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
11.6
109
537
R4190
NOMESCO Finland
Nutritional therapy
2.9
11.5
53
187
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
11.5
11
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
11.4
452
3406
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
11.4
124
646
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
15.2
11.3
18
12
A04AA01
ATC
ondansetron; systemic, rectal
2.2
11.0
96
459
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.9
10.8
51
182
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
10.8
91
430
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.5
10.7
69
289
B03XA02
ATC
darbepoetin alfa; parenteral
3.8
10.5
32
87
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
111.1
10.4
11
*
D72.1
ICD-10 Finland
Eosinophilia
+∞
10.4
10
*
L04AD01
ATC
ciclosporin; systemic
3.9
10.3
30
79
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.6
10.2
59
235
JN4BD
NOMESCO Finland
Extensive body CT
2.0
10.1
114
602
J01MA02
ATC
ciprofloxacin; systemic
1.5
9.8
392
2932
L03AB04
ATC
interferon alfa-2a; parenteral
26.3
9.8
13
5
J01MA12
ATC
levofloxacin; systemic
1.7
9.8
195
1230
C03DA01
ATC
spironolactone; oral
1.9
9.7
141
811
S16
ICPC
Bruise/contusion
3.1
9.7
41
138
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
9.6
331
2392
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.6
265
1819
TK800
NOMESCO Finland
Hemodialysis
3.6
9.6
31
88
L01XE18
ATC
[U] ruxolitinib
100.9
9.4
10
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
100.9
9.4
10
*
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
8.1
9.4
20
25
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
21.9
9.4
13
6
ZXA00
NOMESCO Finland
Right side
1.6
9.3
279
1950
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
9.3
116
634
R53
ICD-10 Finland
Malaise and fatigue
1.6
9.2
254
1741
C07AB07
ATC
bisoprolol; oral
1.5
9.2
505
4024
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.2
301
2148
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
9.0
196
1264
L01XE01
ATC
[U] imatinib
37.0
9.0
11
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
9.0
105
561
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
18.8
8.9
13
7
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
8.9
255
1763
ZXA10
NOMESCO Finland
Bilateral
1.7
8.8
190
1224
127
Kela drug reimbursment
Transplant complication
4.2
8.7
23
56
R06.0
ICD-10 Finland
Dyspnoea
1.6
8.7
286
2037
AA1AD
NOMESCO Finland
CT of head and brain
1.5
8.7
305
2204
122
Kela drug reimbursment
Aplastic anaemia
50.4
8.7
10
*
A91
ICPC
Abnormal result investigation NOS
2.2
8.6
69
319
Z2446
NOMESCO Finland
Social worker
2.2
8.6
73
346
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
8.6
71
333
J01DB01
ATC
cefalexin; oral
1.6
8.6
822
7312
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.5
348
2598
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.4
703
6051
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
8.4
101
545
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
9.5
8.3
16
17
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.2
435
3417
Z71.8
ICD-10 Finland
Other specified counselling
1.5
8.1
330
2456
R4120
NOMESCO Finland
Occupational therapy
2.1
8.1
74
361
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
10.1
8.0
15
15
J01CA04
ATC
amoxicillin; systemic
1.6
8.0
801
7117
B01AB04
ATC
dalteparin; parenteral
2.4
8.0
53
226
R71
ICD-10 Finland
Abnormality of red blood cells
10.9
7.8
14
13
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
7.0
7.8
18
26
J05AB11
ATC
valaciclovir; oral
1.7
7.8
152
952
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
7.8
136
826
M79.6
ICD-10 Finland
Pain in limb
1.5
7.7
437
3467
L04AX04
ATC
lenalidomide; oral
7.5
7.7
17
23
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
7.7
203
1372
A97
ICPC
No disease
1.6
7.6
205
1391
B01AA03
ATC
warfarin; systemic
1.6
7.6
184
1217
D07AC01
ATC
betamethasone; topical
1.5
7.6
354
2704
3AC01, ,
NOMESCO Finland
6.2
7.6
19
31
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.5
121
716
H02AB07
ATC
prednisone; oral
1.7
7.5
136
833
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.2
7.5
17
24
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.3
173
1136
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
7.3
50
216
D73.0
ICD-10 Finland
Hyposplenism
+∞
7.3
7
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
7.4
7.2
16
22
N03AX16
ATC
[U] pregabalin
1.5
7.2
226
1588
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
30.2
7.2
9
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
20.2
7.1
10
5
T90
ICPC
Diabetes non-insulin dependent
1.5
7.1
249
1789
153
Kela drug reimbursment
Lenalidomid
7.0
7.0
16
23
UJF30, ,
SPAT
4.4
7.0
17
39
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
7.0
139
874
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.9
263
1924
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.4
6.9
44
185
N06AX11
ATC
mirtazapine; oral
1.5
6.9
333
2552
XW000, ,
SPAT
40.3
6.8
8
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.9
6.7
86
475
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.1
6.6
62
306
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.6
378
2982
UJF32
NOMESCO Finland
Coloscopy
1.5
6.6
260
1913
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
3.1
6.5
26
85
B01AC04
ATC
clopidogrel; oral
1.6
6.5
169
1137
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.4
258
1902
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.4
257
1894
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
6.4
74
395
A02BC01
ATC
omeprazole; systemic
1.5
6.4
263
1949
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.4
488
4040
329
Kela drug reimbursment
Lenalidomide
8.2
6.3
13
16
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
6.3
186
1285
Z01.7
ICD-10 Finland
Laboratory examination
1.6
6.3
167
1126
ZXA05
NOMESCO Finland
Left side
1.5
6.3
237
1725
D61.9
ICD-10 Finland
Aplastic anaemia, unspecified
18.1
6.3
9
5
SPAT1262
SPAT
Handing over of treatment supplies
1.6
6.3
166
1120
C91.4
ICD-10 Finland
Hairy-cell leukaemia
+∞
6.3
6
*
9940/3-C42.1
ICD-O-3
Hairy cell leukemia, NOS, of bone marrow
+∞
6.3
6
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
6.3
6
*
H02AB04
ATC
methylprednisolone; systemic
1.6
6.2
141
915
D58.2
ICD-10 Finland
Other haemoglobinopathies
26.8
6.2
8
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.2
439
3583
J01FA10
ATC
azithromycin; systemic
1.4
6.2
525
4414
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.6
6.2
20
57
L17
ICPC
Foot/toe symptom/complaint
1.4
6.2
301
2301
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
6.2
47
214
L29
ICPC
Musculoskeletal sympt/complt other
1.8
6.2
95
556
L14
ICPC
Leg/thigh symptom/complaint
1.8
6.1
84
474
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
6.1
34
134
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.0
615
5318
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
255
152
21.96
318.44
1.5
1.2
52.48
37.46
u/l
0.40
225
135
227
103
27.98
318.33
1.1
1.0
—
—
—
0
0
594
1088
11.52
307.65
8.7
4.0
250.76
247.28
u/l
0.14
586
1024
381
122
48.95
307.65
1.8
1.8
—
—
—
0
0
460
838
9.11
268.23
4.5
2.7
76.80
70.13
e9/l
2.17
288
631
468
1372
5.42
155.16
3.6
2.6
24.86
22.45
%
2.52
452
1284
473
1482
5.05
142.61
3.6
2.5
2.30
2.30
g/l
0.04
453
1379
479
1599
4.73
131.31
3.7
2.6
14.07
12.75
umol/l
2.87
460
1490
196
302
7.78
126.02
5.3
2.6
0.05
0.02
g/l
0.38
180
276
227
427
6.53
120.44
2.9
1.8
1.21
1.54
g/l
5.02
207
378
203
344
7.10
119.26
5.3
2.8
1.96
1.12
g/l
1.31
185
309
188
298
7.49
117.48
5.2
2.6
0.00
0.00
g/l
-0.00
172
262
177
273
7.62
113.24
5.4
2.7
0.00
0.00
g/l
-0.00
172
261
203
374
6.51
109.46
5.4
2.5
2.97
2.99
g/l
0.08
195
349
861
4878
5.64
107.82
17.0
6.4
0.22
0.19
e9/l
1.37
752
4255
849
4812
5.33
104.73
15.6
6.2
2.34
1.91
e9/l
1.27
746
4230
205
400
6.15
103.97
5.3
2.5
4.04
4.22
g/l
1.68
196
375
205
400
6.15
103.97
5.3
2.5
3.68
3.71
g/l
0.08
197
375
205
400
6.15
103.97
5.3
2.5
6.75
7.43
g/l
5.86
197
375
189
344
6.50
102.88
5.2
2.5
10.75
10.65
g/l
0.08
180
317
177
330
6.27
93.67
5.9
3.8
60.56
65.81
mg/l
0.10
162
288
177
330
6.27
93.67
5.9
3.8
52.91
51.40
mg/l
0.04
162
290
872
5275
5.23
92.66
23.9
9.2
4.58
4.16
e9/l
2.40
759
4583
166
294
6.54
92.48
6.0
3.6
4.67
2.55
ratio
0.45
84
170
540
2405
3.61
90.42
4.4
2.8
351.80
346.92
umol/l
0.45
507
2111
740
4044
3.94
89.53
23.7
11.3
0.02
0.00
e9/l
1.28
570
3308
282
821
4.35
88.07
4.6
2.9
66.55
66.72
g/l
0.13
268
767
508
2340
3.31
77.50
8.3
4.1
85.87
89.67
%
2.69
496
2299
144
264
6.18
77.01
3.1
2.2
91.86
91.58
%
0.05
136
256
218
585
4.46
74.89
2.5
1.7
1.61
1.45
g/l
0.28
204
540
67
48
14.86
73.86
1.6
1.4
—
—
—
0
0
67
48
14.86
73.86
1.6
1.4
—
—
—
0
0
247
736
4.10
73.62
3.2
2.8
10.55
11.01
g/l
0.59
234
677
129
222
6.50
73.43
1.6
1.7
—
—
—
0
0
48
17
29.57
71.68
1.0
1.9
—
—
—
0
0
499
2456
3.00
64.87
3.2
2.2
3.07
2.89
mg/l
0.49
441
2103
776
4907
3.35
63.43
11.8
6.5
11.58
11.68
umol/l
0.11
764
4702
284
1059
3.32
59.13
5.4
2.9
6.25
8.19
umol/l
2.05
254
951
694
4218
2.97
58.86
5.5
3.0
163.62
131.60
ug/l
0.93
661
3924
127
270
5.22
57.37
1.3
1.3
—
—
—
0
0
683
4159
2.90
56.91
9.7
5.1
35.78
35.53
g/l
0.55
661
3928
318
1308
3.07
55.61
8.3
5.8
1.05
1.03
mmol/l
0.40
307
1212
683
4277
2.77
51.78
10.9
6.6
1.22
1.21
mmol/l
1.63
656
3956
88
148
6.41
50.88
1.4
1.4
147.92
154.84
au/ml
0.19
38
41
714
4753
2.63
44.74
11.9
7.3
1.21
1.21
mmol/l
0.33
623
4125
476
2654
2.47
43.52
4.5
3.3
0.66
0.43
e6/l
0.92
346
1975
321
1541
2.57
39.84
4.0
3.2
1.86
2.36
e6/l
0.61
154
784
904
6993
3.38
38.96
18.2
8.2
81.73
79.11
u/l
1.20
883
6625
562
3490
2.34
38.85
5.8
4.1
99.72
104.02
e6/l
0.05
396
2497
46
9
53.39
38.85
1.0
1.4
—
—
—
0
0
219
877
2.90
38.71
2.8
2.4
35.98
35.48
u/l
0.05
188
734
358
1836
2.46
38.31
2.2
1.5
2.52
2.50
g/l
0.06
248
1122
512
3094
2.30
37.26
4.5
3.4
45.73
84.38
e6/l
0.80
382
2400
301
1475
2.47
35.11
3.6
2.0
30.16
29.54
s
1.09
293
1433
73
148
5.23
34.50
3.6
2.5
1166.00
425.17
u/ml
—
5
12
83
190
4.66
34.00
6.1
5.5
810.17
405.71
iu/ml
0.24
12
21
465
2811
2.19
32.51
2.3
1.7
20.10
20.16
nmol/l
0.03
426
2361
30
0
+∞
31.41
7.6
0.0
—
—
—
0
0
312
1623
2.32
31.27
4.8
3.3
0.81
0.82
mmol/l
0.58
303
1539
620
4236
2.16
31.17
3.0
2.2
90.60
95.45
pmol/l
2.09
390
2215
365
2035
2.23
30.90
2.5
1.7
1.41
1.20
mg/l
0.67
307
1585
75
173
4.60
30.40
1.4
1.3
209.91
275.06
u/ml
0.98
45
95
314
1665
2.27
29.87
3.9
3.0
1.27
1.16
e6/l
0.08
153
916
333
1820
2.23
29.34
5.2
4.1
177.32
527.70
ng/l
2.48
279
1439
854
6732
2.56
29.25
6.0
4.5
15.96
12.40
mm/h
5.68
810
6278
486
3091
2.08
28.73
5.3
3.3
33.42
33.43
u/l
0.00
471
2924
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
28
27
10.63
25.43
1.6
2.8
147.91
132.67
%
0.37
28
27
332
1920
2.08
24.52
3.5
3.0
2.45
2.45
mmol/l
0.07
303
1729
34
46
7.61
23.86
2.0
2.2
—
—
—
0
0
46
86
5.55
23.71
2.3
2.4
57.74
57.89
iu/ml
—
5
10
237
1223
2.22
23.35
2.5
1.8
—
—
—
0
0
27
5
55.37
23.14
1.1
1.0
—
—
—
0
0
487
3282
1.92
22.71
4.5
3.5
2.35
2.36
mmol/l
0.96
453
2977
81
248
3.46
22.15
3.6
3.2
4.22
2.19
index
0.36
55
133
223
1146
2.21
22.08
2.5
1.9
—
—
—
0
0
287
1627
2.06
22.00
1.9
1.7
1091.83
1180.63
nmol/l
0.76
214
1235
156
693
2.47
21.61
2.2
1.6
—
—
—
0
0
651
4872
1.91
21.51
4.3
4.1
0.00
0.01
estimate
1.46
171
954
33
49
6.92
21.33
2.1
2.3
299.82
201.57
e6/l
0.61
28
42
707
5453
1.94
21.12
9.5
5.2
6.74
6.71
mmol/l
0.15
686
5206
181
870
2.31
20.97
10.8
7.4
10.38
9.89
mmol/l
0.37
174
834
57
142
4.19
20.91
6.5
3.6
1.07
1.35
%
0.28
45
133
644
4832
1.89
20.77
4.2
4.1
7.48
4.82
estimate
0.13
180
1020
639
4785
1.88
20.71
4.2
4.0
0.00
0.00
estimate
0.50
176
997
280
1608
2.02
20.50
2.6
1.9
—
—
—
0
0
343
2138
1.91
19.61
3.3
2.7
4.59
5.29
e6/l
0.55
309
1959
863
7235
2.18
19.17
49.0
20.3
14.76
13.65
%
36.38
857
7144
22
5
44.87
18.29
5.1
4.6
—
—
—
0
0
80
276
3.06
17.98
2.4
1.7
0.25
0.24
g/l
0.50
73
266
30
49
6.28
17.73
2.0
2.1
698.62
521.95
e6/l
0.69
24
38
39
84
4.79
17.16
2.1
2.2
1157.88
1120.58
mg
0.03
39
84
351
2285
1.81
17.00
5.9
2.3
—
—
—
0
0
80
285
2.96
16.99
2.4
1.7
1.22
1.18
g/l
0.59
74
273
130
606
2.31
15.98
2.3
1.7
—
—
—
0
0
731
5940
1.79
15.74
6.0
4.8
489.83
2031.33
e6/l
—
6
99
574
4367
1.71
15.58
22.0
14.9
1.28
1.26
inr
0.47
483
3644
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
82
312
2.77
15.43
4.7
2.6
0.32
0.37
iu/ml
0.67
47
165
40
96
4.29
15.41
1.1
1.1
—
—
—
0
0
47
128
3.80
15.28
1.5
1.6
—
—
—
0
0
55
170
3.36
14.82
1.5
1.3
—
—
—
0
0
55
170
3.36
14.82
1.5
1.3
—
—
—
0
0
416
2938
1.70
14.61
2.5
2.2
198.60
223.56
u/l
0.19
398
2801
174
943
2.02
14.51
3.1
2.3
0.21
0.21
g/l
0.19
162
882
175
964
1.98
13.90
5.6
3.6
0.91
1.92
mmol/l
2.19
151
827
67
242
2.89
13.89
1.7
1.6
—
—
—
0
0
33
77
4.39
13.19
1.2
1.1
270.00
186.15
titre
—
6
13
177
1000
1.93
13.01
5.7
3.5
5.80
5.79
kpa
0.03
171
972
26
50
5.31
13.01
1.5
1.1
—
—
—
0
0
44
129
3.52
12.87
1.5
1.2
3.96
2.67
u/ml
0.20
23
46
956
8667
2.42
12.71
34.8
16.5
23.73
24.69
mg/l
0.42
861
7184
36
93
3.97
12.61
1.3
1.2
—
—
—
0
0
540
4185
1.61
12.49
3.3
2.5
79.19
77.41
nmol/l
0.73
498
3752
21
16
13.37
12.46
1.1
1.2
—
—
—
0
0
162
901
1.95
12.44
2.5
2.1
361.52
381.79
nmol/l
0.67
155
844
66
254
2.71
12.16
1.7
1.6
—
—
—
0
0
43
130
3.41
12.01
1.6
1.2
5.15
5.15
u/ml
0.00
27
52
190
1135
1.83
11.66
9.8
8.3
-0.09
0.98
mmol/l
2.68
171
936
546
4290
1.58
11.57
5.9
2.8
—
—
estimate
—
0
0
25
52
4.90
11.47
2.8
1.3
11.14
6.60
ug/l
1.20
25
46
140
761
1.97
11.46
5.3
3.9
105.83
90.05
ng/l
0.94
128
670
40
1069
0.35
10.48
7.6
7.3
—
—
—
0
0
493
3840
1.54
10.47
2.3
2.0
1.46
1.35
mmol/l
2.15
405
3221
168
997
1.82
10.46
4.4
3.2
—
—
—
0
0
38
118
3.31
10.21
1.2
1.1
—
—
—
0
0
21
25
8.55
10.07
1.1
1.0
—
—
—
0
0
120
656
1.94
9.62
13.0
10.0
93.65
93.98
%
0.23
120
651
20
40
5.08
9.59
1.2
1.4
58.13
69.17
mg/l
0.35
15
30
394
2971
1.53
9.42
3.9
3.2
2173.32
1297.71
ng/l
2.03
327
2563
85
413
2.15
9.40
2.1
2.2
39.19
38.80
u/l
0.06
74
366
64
277
2.40
9.29
2.0
1.6
—
—
—
0
0
81
391
2.16
9.11
2.1
2.0
13.96
7.87
iu/ml
0.57
12
90
54
219
2.55
9.01
1.5
1.4
—
—
—
0
0
128
733
1.85
8.90
3.4
3.0
230.68
211.24
ng/l
0.20
119
678
49
191
2.64
8.85
1.3
1.4
—
—
—
0
0
54
222
2.51
8.76
1.5
1.4
—
—
—
0
0
13
9
14.61
8.21
1.2
1.1
—
—
—
0
0
65
300
2.25
8.17
1.5
1.6
0.04
0.08
iu/ml
0.38
17
46
126
746
1.78
7.84
5.2
3.8
1.22
1.23
mmol/l
0.19
103
644
61
282
2.24
7.65
1.6
1.3
—
—
—
0
0
30
97
3.16
7.60
7.6
3.3
54.63
56.93
%
0.15
19
89
40
153
2.68
7.53
1.3
1.3
—
—
—
0
0
18
41
4.45
7.45
1.2
1.1
—
—
—
0
0
32
109
3.00
7.44
1.5
1.3
0.18
0.19
nmol/l
0.10
25
83
175
1152
1.63
7.36
2.7
2.4
141.14
119.26
ug/g
0.29
148
930
687
5961
1.46
7.29
4.8
3.4
57.95
50.19
u/l
1.19
659
5606
23
65
3.60
7.17
1.2
1.2
—
—
—
0
0
23
65
3.60
7.17
1.2
1.2
—
—
—
0
0
413
3275
1.44
7.14
5.0
4.1
18.49
8.96
mg/mmol
2.15
265
2045
21
56
3.81
7.10
4.4
3.5
0.81
0.91
index
0.29
21
56
93
517
1.88
7.09
3.0
3.7
4.36
4.46
pmol/l
0.43
85
460
280
2068
1.49
6.99
1.4
1.3
2.04
1.57
u/ml
0.20
52
571
914
8461
1.71
6.90
35.5
15.9
79.09
79.61
ml/min/173m2
0.31
869
7847
23
67
3.49
6.87
1.2
1.2
—
—
—
0
0
23
67
3.49
6.87
1.2
1.2
—
—
—
0
0
889
8175
1.64
6.84
6.5
5.4
1.94
1.97
mu/l
0.21
838
7527
12
11
11.02
6.80
1.1
1.5
105.42
110.36
%
0.18
12
11
10
6
16.81
6.75
1.0
1.0
—
—
—
0
0
336
2588
1.44
6.71
4.1
3.4
0.00
0.01
estimate
1.68
146
791
955
8969
1.88
6.63
36.5
19.6
139.46
139.69
mmol/l
2.06
943
8803
132
833
1.67
6.53
3.8
3.0
4.45
4.51
kpa
0.12
126
809
955
8983
1.86
6.39
39.2
19.8
3.98
3.98
mmol/l
0.04
941
8799
61
305
2.06
6.31
2.3
1.7
—
—
—
0
0
21
61
3.49
6.31
1.8
1.5
—
—
—
0
0
26
87
3.04
6.26
4.7
3.4
16.43
11.21
index
1.42
21
56
417
3380
1.39
6.10
4.6
3.4
7.49
7.62
mmol/l
0.21
341
2854
23
74
3.16
5.92
1.2
1.1
—
—
—
0
0
32
125
2.61
5.83
1.5
1.3
0.84
0.64
nmol/l
0.85
32
119
24
80
3.05
5.83
1.2
1.2
—
—
—
0
0
768
6917
1.43
5.83
5.1
4.4
14.85
14.85
pmol/l
0.01
704
6343
597
5155
1.38
5.82
3.3
2.9
—
—
—
0
0
32
126
2.59
5.75
1.6
1.3
376.67
294.19
pmol/l
0.45
27
111
14
23
6.16
5.70
1.1
2.1
75.57
97.92
%
—
7
13
14
23
6.16
5.70
1.2
1.3
70.57
95.62
%
—
7
13
21
66
3.23
5.61
1.6
2.5
26.25
31.24
mg/l
0.26
16
50
48
231
2.13
5.52
1.6
1.4
9.33
9.32
u/l
0.00
32
186
28
109
2.61
5.16
3.0
3.9
—
—
—
0
0
68
1153
0.56
5.12
5.4
5.0
29.02
32.20
%
1.99
52
747
893
8338
1.53
5.12
7.9
6.7
39.38
39.45
mmol/mol
0.07
845
7807
9
9
10.07
5.03
1.0
2.1
—
—
—
0
0
63
347
1.87
4.99
1.6
1.4
22.31
26.12
iu/l
0.51
49
301
963
9167
1.77
4.96
25.3
12.4
26.58
26.09
u/l
0.45
943
8904
15
33
4.60
4.87
1.1
2.5
—
73835.50
—
0
6
15
34
4.46
4.75
3.8
3.1
0.61
0.61
mmol/l
0.02
15
34
59
324
1.87
4.73
1.7
1.6
36.72
9.56
u/ml
1.04
12
69
22
80
2.79
4.63
1.2
1.0
—
—
—
0
0
68
394
1.78
4.60
1.4
1.7
0.42
0.35
mg/l
0.19
19
183
55
300
1.88
4.52
1.6
1.3
—
—
—
0
0
36
169
2.17
4.45
1.9
1.7
—
—
—
0
0
17
55
3.13
4.37
1.2
1.2
—
—
—
0
0
143
1011
1.48
4.31
3.1
4.4
4.82
22.34
ug/l
1.39
118
832
29
126
2.34
4.30
1.5
1.5
—
—
—
0
0
14
41
3.45
4.19
1.2
1.1
—
—
—
0
0
27
115
2.38
4.18
1.4
1.4
—
—
—
0
0
54
301
1.84
4.16
1.4
1.5
275.03
280.95
ug/g
0.06
32
178
11
21
5.28
4.15
1.4
1.7
90.09
65.24
nmol/24h
0.40
11
21
966
9260
1.69
4.08
43.1
21.6
82.60
78.51
umol/l
2.76
957
9158
25
104
2.44
4.08
1.2
1.3
248.60
403.06
u/l
0.72
25
98
357
2970
1.31
3.98
3.4
2.6
54.05
87.53
u/l
0.67
333
2767
111
760
1.52
3.91
3.4
2.8
62.03
65.88
ml/min/173m2
0.53
69
319
59
348
1.74
3.80
2.3
2.9
—
—
—
0
0
48
266
1.84
3.79
1.4
1.3
—
—
—
0
0
90
597
1.56
3.67
1.3
1.2
195.42
143.46
u/ml
0.52
36
240
14
40
3.53
3.61
1.0
1.1
—
—
—
0
0
189
1451
1.37
3.60
1.6
1.5
—
—
—
0
0
18
68
2.68
3.57
1.7
1.4
13.11
13.42
u/l
0.06
18
62
90
607
1.53
3.42
1.5
1.3
156.87
240.05
u/ml
0.65
79
558
9
18
5.03
3.37
1.3
1.3
—
—
—
0
0
39
211
1.88
3.35
1.6
1.3
4.24
59.37
e6/l
1.11
29
153
14
48
2.94
3.31
1.2
1.0
—
—
—
0
0
39
212
1.87
3.30
1.6
1.3
166.47
663.02
e6/l
0.43
30
160
13
43
3.05
3.26
1.4
1.4
144.00
162.67
mmol/24h
0.39
13
43
7
11
6.40
3.19
1.1
1.0
—
—
—
0
0
29
145
2.03
3.12
1.4
1.5
30.72
31.96
g/l
0.21
24
130
46
274
1.71
2.92
1.5
1.2
—
20.31
—
0
17
14
52
2.72
2.89
1.5
2.3
—
—
—
0
0
41
238
1.75
2.85
3.4
2.1
134.17
129.60
g/l
0.39
30
187
239
1960
1.29
2.84
1.8
1.8
30481773.43
36730141.91
pmol/l
0.07
187
1639
26
130
2.03
2.82
1.3
1.4
954.37
1648.98
e6/l
1.23
19
83
918
8803
1.39
2.79
7.1
6.0
2.49
2.68
mmol/l
8.34
878
8159
60
392
1.56
2.68
2.8
3.6
591.56
3807.65
u/ml
0.67
51
340
9
24
3.77
2.67
1.3
1.1
—
—
—
0
0
86
608
1.45
2.65
2.4
2.5
6.83
21.70
au/ml
—
7
47
20
93
2.17
2.62
1.4
1.7
—
—
—
0
0
888
8488
1.33
2.62
5.8
5.3
6.02
5.98
mmol/l
0.38
826
7778
137
1052
1.35
2.61
1.8
1.8
1.60
1.51
%
0.64
116
912
79
551
1.47
2.61
1.3
1.3
36.29
56.28
au/ml
—
7
43
23
114
2.04
2.57
1.4
1.4
199560.80
33972.50
e6/l
0.64
15
58
32
182
1.78
2.42
3.8
3.3
9.88
8.61
pmol/l
0.26
32
182
210
1732
1.27
2.37
1.4
1.3
36.23
32.04
iu/ml
0.11
59
545
78
562
1.42
2.20
4.0
3.6
2.00
1.86
mmol/l
0.11
54
415
32
188
1.72
2.19
1.2
1.3
—
64.00
—
0
5
191
1579
1.26
2.11
1.3
1.3
15.81
12.37
u/ml
0.21
51
600
896
8627
1.29
2.10
6.1
5.2
1.31
1.46
mmol/l
26.32
855
7979
6
15
4.02
2.04
1.5
1.5
—
—
—
0
0
20
104
1.94
2.01
1.4
1.3
284.00
278.51
mosm/kgh2o
0.28
14
77
69
496
1.42
2.00
1.7
1.4
—
—
—
0
0
861
8262
1.26
1.99
5.1
4.4
1.43
1.29
mmol/l
5.14
817
7572
5
11
4.56
1.94
8.4
7.2
5.34
5.81
mmol/l
—
5
11
967
9432
1.41
1.91
54.5
25.0
92.48
91.24
fl
5.47
959
9335
967
9433
1.40
1.90
54.7
25.1
310.06
248.01
e9/l
28.74
947
9256
898
8672
1.28
1.87
6.3
5.3
4.27
4.60
mmol/l
17.52
866
8070
967
9435
1.40
1.87
56.0
25.6
40.01
40.29
%
0.75
959
9331
967
9435
1.40
1.87
54.5
25.0
4.44
4.48
e12/l
0.72
945
9228
967
9437
1.40
1.85
55.1
25.2
131.77
134.93
g/l
5.17
959
9338
97
748
1.33
1.84
3.8
2.4
13.37
13.39
nmol/l
0.01
91
676
403
3631
1.18
1.83
4.2
4.0
0.03
0.04
estimate
0.16
147
822
5
12
4.18
1.82
1.0
1.2
—
—
—
0
0
37
239
1.57
1.81
1.5
2.0
2.48
27.70
iu/l
—
10
99
31
193
1.63
1.76
1.6
1.4
—
—
—
0
0
97
756
1.31
1.72
1.6
1.4
—
—
—
0
0
26
156
1.68
1.70
1.7
1.5
—
—
—
0
0
20
111
1.82
1.69
1.6
1.5
0.35
0.33
nmol/l
0.05
15
86
22
126
1.76
1.69
1.1
1.1
—
—
—
0
0
39
260
1.52
1.68
1.2
1.1
—
—
—
0
0
207
1779
1.20
1.59
3.1
3.2
0.59
0.75
ug/l
3.60
145
1171
85
659
1.32
1.58
4.5
3.7
5.25
5.16
kpa
0.40
79
634
12
57
2.12
1.55
1.2
1.4
—
—
—
0
0
15
79
1.91
1.50
1.7
1.5
—
—
—
0
0
18
101
1.80
1.49
2.1
1.8
—
—
—
0
0
17
94
1.82
1.48
1.0
1.1
—
—
—
0
0
397
3626
1.15
1.45
5.0
3.9
43.35
62.47
ng/l
0.49
291
2660
5
16
3.13
1.44
6.6
2.4
57.60
46.87
u/l
—
5
16
39
270
1.46
1.43
2.0
1.4
—
—
—
0
0
10
199
0.50
1.41
1.9
3.8
28.44
26.06
mg/l
—
10
141
302
2709
1.16
1.40
4.5
4.1
0.01
0.01
estimate
0.02
164
932
11
53
2.09
1.39
1.0
1.2
61.62
29.20
u/l
0.36
11
48
21
334
0.62
1.36
3.6
4.0
1.30
1.37
mmol/l
0.23
21
326
15
83
1.82
1.31
1.0
1.1
—
—
—
0
0
14
244
0.57
1.30
1.2
1.4
—
—
—
0
0
9
43
2.10
1.30
3.0
3.7
—
—
—
0
0
9
43
2.10
1.30
1.1
1.3
—
—
—
0
0
54
405
1.35
1.29
1.3
1.3
—
—
—
0
0
37
260
1.44
1.28
1.2
1.2
—
—
—
0
0
12
62
1.95
1.28
2.2
1.2
—
—
—
0
0
12
62
1.95
1.28
2.2
1.2
—
—
—
0
0
29
194
1.51
1.28
2.2
2.1
7755.62
5507.91
u/l
—
8
76
9
44
2.05
1.27
1.0
1.3
—
—
—
0
0
8
37
2.17
1.21
1.0
1.4
—
—
—
0
0
19
117
1.64
1.18
1.2
1.1
9.78
2.04
eliau/ml
—
6
46
15
88
1.71
1.11
1.0
1.1
—
—
—
0
0
12
66
1.83
1.09
1.0
1.4
2.88
3.02
ug/l
—
7
53
192
2163
0.86
1.09
3.9
4.3
1.02
1.02
kg/l
0.26
142
1461
23
153
1.51
1.07
1.2
1.1
2.72
1.62
u/ml
0.22
16
78
12
67
1.80
1.05
2.3
2.3
666.50
628.98
ml
—
6
45
15
90
1.68
1.04
2.3
1.9
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
18
272
0.66
0.98
3.9
4.0
3.84
3.90
mmol/l
0.19
18
267
9
49
1.84
0.98
1.7
1.7
63.78
51.52
ug/l
—
9
49
7
36
1.95
0.97
1.7
1.2
—
—
—
0
0
19
125
1.53
0.94
1.1
1.0
0.10
1.82
u/ml
1.37
13
57
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
52
1.74
0.92
1.6
1.2
—
—
—
0
0
10
55
1.83
0.92
1.1
1.1
—
—
—
0
0
6
28
2.15
0.91
1.5
1.2
2.10
5.13
umol/l
—
6
23
8
42
1.91
0.88
3.3
1.7
40.77
39.90
g/l
—
8
42
49
614
0.79
0.87
1.6
1.7
3.41
3.51
mmol/l
0.33
42
455
10
57
1.76
0.84
1.1
1.0
—
—
—
0
0
10
57
1.76
0.84
1.4
1.3
134.11
173.79
pmol/l
—
10
57
6
32
1.88
0.82
2.5
1.8
—
—
—
0
0
6
32
1.88
0.82
2.5
1.8
—
—
—
0
0
6
33
1.82
0.79
2.5
1.8
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
27.80
—
0
25
8
48
1.67
0.79
1.0
1.1
407.13
513.67
u/l
—
8
42
15
98
1.54
0.78
1.3
1.2
—
—
—
0
0
14
90
1.56
0.78
1.5
2.7
—
—
—
0
0
14
91
1.55
0.75
1.0
1.0
0.78
0.64
u/ml
—
8
24
36
280
1.30
0.75
1.6
1.2
0.87
0.91
g/l
0.31
36
280
5
24
2.09
0.74
1.0
1.2
—
—
—
0
0
7
38
1.85
0.73
1.0
1.0
1339.43
1586.82
miu/ml
—
7
38
5
25
2.00
0.72
1.6
1.2
—
—
—
0
0
5
25
2.00
0.72
1.6
1.2
—
—
—
0
0
7
39
1.80
0.72
1.0
1.0
—
—
—
0
0
14
92
1.53
0.72
1.9
1.2
—
61.88
—
0
8
72
845
0.84
0.71
2.0
2.0
3.73
3.47
ratio
0.94
62
682
140
1254
1.13
0.69
1.6
1.5
—
—
—
0
0
6
104
0.57
0.62
1.5
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
7.9
—
69.06
—
0
17
6
35
1.72
0.57
1.0
1.1
105.13
195.06
iu/ml
—
6
35
29
229
1.27
0.57
3.2
2.4
265.20
99.82
ug/min
0.41
15
139
20
150
1.34
0.56
1.8
1.6
—
—
—
0
0
9
61
1.48
0.53
1.6
1.4
—
—
—
0
0
30
241
1.25
0.53
1.2
1.2
—
—
—
0
0
6
41
1.47
0.50
1.8
1.3
13.67
8.83
mm/h
—
6
41
11
76
1.45
0.48
1.1
1.1
128.64
103.43
pmol/l
1.00
11
76
7
48
1.46
0.47
1.4
1.4
—
—
—
0
0
7
48
1.46
0.47
1.4
1.4
—
—
—
0
0
33
275
1.21
0.44
1.3
1.4
—
—
—
0
0
31
257
1.21
0.43
1.8
1.6
23206.95
14214.18
e6/l
0.32
22
181
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
8
59
1.36
0.41
1.6
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
1.18
—
0
17
0
17
0.00
0.40
0.0
1.1
—
1.04
—
0
7
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
11
80
1.38
0.38
1.6
1.2
—
—
—
0
0
9
71
1.27
0.36
1.6
1.4
—
—
—
0
0
6
42
1.43
0.35
2.5
1.7
—
—
—
0
0
6
42
1.43
0.35
2.5
1.7
—
—
—
0
0
6
42
1.43
0.35
2.5
1.7
—
—
—
0
0
6
42
1.43
0.35
2.5
1.7
—
—
—
0
0
45
395
1.15
0.35
1.5
2.0
—
—
—
0
0
6
44
1.37
0.34
1.3
1.8
—
—
—
0
0
28
238
1.18
0.32
1.3
1.3
183.24
241.45
miu/ml
0.42
15
115
77
836
0.91
0.29
2.8
2.5
0.49
0.40
e6/l
0.16
77
800
25
213
1.18
0.29
1.6
1.6
—
—
—
0
0
8
64
1.25
0.27
1.4
1.4
—
34.29
—
0
7
49
442
1.11
0.27
1.1
1.0
—
—
—
0
0
5
75
0.67
0.26
1.0
1.0
197.80
300.06
ng/l
—
5
50
5
75
0.67
0.26
1.0
1.0
24.60
41.16
ng/l
—
5
48
11
138
0.79
0.25
1.3
1.4
—
—
—
0
0
9
75
1.20
0.25
2.0
1.6
—
—
—
0
0
9
75
1.20
0.25
2.0
1.6
—
—
—
0
0
9
75
1.20
0.25
2.0
1.6
—
—
—
0
0
10
126
0.79
0.24
1.4
1.5
1.44
1.21
ratio
—
5
73
10
126
0.79
0.24
1.4
1.5
1.28
1.12
ratio
—
5
73
10
126
0.79
0.24
1.4
1.5
0.88
0.94
ratio
—
5
73
6
84
0.71
0.24
1.3
1.6
—
—
—
0
0
5
41
1.22
0.22
1.4
1.3
—
—
—
0
0
5
41
1.22
0.22
1.4
1.3
—
—
—
0
0
10
124
0.80
0.21
1.4
1.5
—
—
—
0
0
77
721
1.07
0.21
2.4
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
6.23
—
0
11
0
10
0.00
0.21
0.0
6.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
23
203
1.14
0.19
1.8
3.7
346.70
323.58
u/ml
0.02
23
191
5
69
0.72
0.17
1.4
1.5
62.88
52.19
ug/l
—
5
69
35
322
1.09
0.15
1.4
2.0
—
—
—
0
0
9
79
1.14
0.15
2.2
1.2
—
43.40
—
0
5
7
89
0.79
0.14
1.9
1.5
—
—
—
0
0
82
784
1.05
0.13
2.4
2.1
—
—
—
0
0
9
109
0.82
0.13
1.2
1.2
7.48
7.22
mmol/l
—
9
91
246
2417
1.02
0.10
3.9
4.6
23.83
21.51
%
1.17
103
1181
5
47
1.06
0.09
7.2
3.3
1.20
1.17
%
—
5
47
306
3020
1.02
0.09
5.0
5.6
2.06
2.50
ug/l
0.75
270
2708
6
58
1.03
0.08
1.8
1.9
18.17
20.83
nmol/l
—
6
49
5
64
0.78
0.08
1.0
1.9
78.42
104.26
ng/l
—
5
64
11
123
0.89
0.08
2.0
1.4
—
—
—
0
0
8
77
1.04
0.07
1.4
1.5
—
—
—
0
0
11
122
0.90
0.07
2.0
1.4
—
—
—
0
0
11
122
0.90
0.07
2.0
1.4
—
—
—
0
0
79
808
0.98
0.05
2.1
2.4
8.17
7.25
ug/l
0.22
71
722
24
252
0.95
0.05
1.0
1.1
0.55
0.71
ratio
—
6
35
10
91
1.10
0.04
1.2
1.3
102516.00
165900.62
e6/l
—
5
60
12
129
0.93
0.03
2.0
1.4
—
—
—
0
0
12
129
0.93
0.03
2.0
1.4
—
—
—
0
0
32
331
0.97
0.03
2.3
1.8
—
—
—
0
0
12
127
0.94
0.01
2.0
1.4
—
—
—
0
0
35
357
0.98
0.01
2.5
1.9
—
—
—
0
0
26
265
0.98
0.00
1.0
1.2
1.51
1.53
g/l
0.18
26
265
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
46
460
1.00
-0.00
2.4
3.8
1.02
1.02
ratio
1.23
40
433
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
65.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_BLOODNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_BLOODNAS | 2.238 [1.91, 2.63] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.245 |
During the follow-up period (1.1.1998 — 31.12.2019), 570 out of 2131 females with D3_BLOODNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_BLOODNAS | 2.256 [1.9, 2.67] | < 0.001 |
| Birth year | 0.981 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 665 out of 1883 males with D3_BLOODNAS died.
Mortality risk
Mortality risk for people of age
years, who have D3_BLOODNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.227% | 0.362% |
| 5 | 1.374% | 2.281% |
| 10 | 3.61% | 5.483% |
| 15 | 6.907% | 9.997% |
| 20 | 11.592% | 16.14% |
Relationships between endpoints
↥Index endpoint: D3_BLOODNAS – Other and unspecified diseases of blood and blood-forming organs
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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