Other diseases of blood and blood-forming organs

D3_OTHERBLOOD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D75
  • Cause of death: ICD-10 D75

2 out of 7 registries used, show all original rules.

3126

4. Check minimum number of events

None

3126

5. Include endpoints

3285

6. Filter based on genotype QC (FinnGen only)

2821

Control definitions (FinnGen only)

Control exclude
D3_BLOODOTHER

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D70-D77
Name in latin
Alii morbi sanguinis et organorum haematopoeticorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17063 8307 8588
Only index persons 14250 7111 7139
Unadjusted period prevalence (%)
Whole population 0.24 0.24 0.24
Only index persons 0.27 0.26 0.27
Median age at first event (years)
Whole population 60.51 61.34 59.66
Only index persons 59.31 60.14 58.49

-FinnGen-

Key figures

All Female Male
Number of individuals 2821 1393 1428
Unadjusted period prevalence (%) 0.58 0.49 0.65
Median age at first event (years) 59.98 58.46 61.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2901
Matched controls
29010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D75.2
ICD-10 Finland
Essential thrombocytosis
2578.4
307.7
999
6
D75.1
ICD-10 Finland
Secondary polycythaemia
1174.3
307.7
894
11
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
1648.1
307.7
827
7
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
148.1
307.7
646
56
D45
ICD-10 Finland
Polycythaemia vera
52.4
307.7
379
83
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
42.3
307.7
321
85
9962/3-C42.1
ICD-O-3
Essential thrombocythemia of bone marrow
201.1
307.7
306
17
XW000
NOMESCO Finland
Bone marrow biopsy
21.9
307.7
796
492
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
26.1
307.7
936
520
L01XX05
ATC
hydroxycarbamide; oral
101.3
307.7
775
104
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
89.1
289.3
152
18
TPH00
NOMESCO Finland
Phlebotomy
35.4
234.4
148
44
SPAT1074
SPAT
Venesection
38.5
220.7
136
37
D75.0
ICD-10 Finland
Familial erythrocytosis
1026.3
198.3
192
*
L03AB05
ATC
interferon alfa-2b; parenteral
47.2
186.0
109
24
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
40.6
168.0
102
26
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
160.3
679
2324
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
816.8
159.1
155
*
L01XX35
ATC
anagrelide; oral
311.6
146.0
147
5
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
61.4
118.5
66
11
TPH00, ,
SPAT
46.4
115.5
68
15
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
43.7
100.5
60
14
L03AB04
ATC
interferon alfa-2a; parenteral
52.8
99.5
57
11
B99
ICPC
Blood/lymph/spleen disease other
21.1
98.1
74
36
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
13.3
96.7
92
71
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
13.7
90.6
85
64
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
89.9
431
1552
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
74.0
1611
11049
R71
ICD-10 Finland
Abnormality of red blood cells
21.5
73.6
55
26
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
82.1
64.3
72
9
M04AA01
ATC
allopurinol; systemic
2.4
63.4
514
2388
D70.89
ICD-10 Finland
Neutropenic splenomegaly
27.0
58.3
40
15
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
6.2
49.1
84
138
28900
ICD-8 Finland
Other disease of blood and blood-forming organs, Polycythaemia, secondary
+∞
48.0
46
*
174
Kela drug reimbursment
Ruxolitinib
90.0
48.0
53
6
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
13.7
45.1
42
31
374
Kela drug reimbursment
Ruxolitinib
99.7
44.9
49
5
212
Kela drug reimbursment
Gout
4.6
42.4
101
224
L01EJ01
ATC
ruxolitinib; oral
76.3
40.0
45
6
WW500
NOMESCO Finland
Blood transfusion
3.3
39.8
155
487
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
10.4
39.6
44
43
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.6
39.1
233
928
B01AB05
ATC
enoxaparin; parenteral
1.7
38.8
960
6457
28998
ICD-8 Finland
Other disease of blood and blood-forming organs, Alii definiti
+∞
38.6
37
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
10.9
38.2
41
38
C03CA01
ATC
furosemide; systemic
1.7
38.1
949
6387
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
14.3
37.4
34
24
28999
ICD-8 Finland
Other disease of blood and blood-forming organs, Other and unspecified
+∞
35.5
34
*
Z2221
NOMESCO Finland
Medical doctor
1.7
35.4
797
5197
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.4
32.1
80
184
ZXE00
NOMESCO Finland
One hour or less
1.6
32.1
1095
7912
B28
ICPC
Limited function/disability (B)
10.1
31.8
36
36
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
31.6
886
6092
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
5.3
31.5
63
120
C07AB07
ATC
bisoprolol; oral
1.6
29.9
1454
11351
H02AB06
ATC
prednisolone; systemic
1.6
29.4
1371
10587
N02AX02
ATC
tramadol; systemic, rectal
1.6
28.7
1253
9516
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
28.6
537
3298
E29.1
ICD-10 Finland
Testicular hypofunction
4.5
26.9
65
146
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
26.6
719
4862
Y28
ICPC
Limited function/disability (Y)
8.8
26.3
33
38
Z3231
NOMESCO Finland
Registered nurse
1.6
26.2
777
5371
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
26.2
570
3641
C03DA01
ATC
spironolactone; oral
1.9
26.2
391
2237
A02BC02
ATC
pantoprazole; systemic
1.6
26.1
1964
16651
R06.0
ICD-10 Finland
Dyspnoea
1.6
25.9
809
5657
T90
ICPC
Diabetes non-insulin dependent
1.6
25.0
744
5136
D70.82
ICD-10 Finland
Drug-induced neutropenia
90.9
24.7
27
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
24.5
668
4512
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
24.5
736
5091
G47.3
ICD-10 Finland
Sleep apnoea
1.6
24.4
704
4823
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
24.1
433
2615
Z3226
NOMESCO Finland
Physiotherapist
1.7
24.1
522
3323
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
23.7
236
1172
SPAT1262
SPAT
Handing over of treatment supplies
1.7
23.7
512
3257
XX7BT
NOMESCO Finland
Radioactive phosphorus therapy
126.1
23.6
25
*
B74
ICPC
Malignant neoplasm blood other
21.5
23.4
34
16
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
23.3
729
5081
R4110
NOMESCO Finland
Physiotherapy
1.6
23.3
795
5652
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
23.0
793
5649
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
22.8
1784
15014
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
22.5
197
929
B01AA03
ATC
warfarin; systemic
1.6
22.4
554
3643
A10BA02
ATC
metformin; oral
1.5
22.2
834
6045
D75
ICD-10 Finland
Other diseases of blood and blood-forming organs
+∞
21.9
21
*
L01XE18
ATC
[U] ruxolitinib
63.0
21.9
25
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
21.6
274
1482
C90.0
ICD-10 Finland
Multiple myeloma
4.3
21.6
55
129
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
21.3
330
1903
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
21.0
281
1548
R50.9
ICD-10 Finland
Fever, unspecified
1.7
20.9
428
2675
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
20.9
333
1938
S97
ICPC
Chronic ulcer skin
2.1
20.8
209
1041
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
20.6
321
1855
J96.1
ICD-10 Finland
Chronic respiratory failure
3.2
20.5
83
268
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
20.4
189
912
C08CA01
ATC
amlodipine; oral
1.5
20.0
1114
8701
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.5
19.8
129
535
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
19.8
448
2874
B03XA01
ATC
erythropoietin; parenteral
5.0
19.7
42
85
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
17.8
19.5
30
17
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
18.3
19.1
29
16
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
18.6
950
7275
J01DB01
ATC
cefalexin; oral
1.5
18.6
2293
20645
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
18.3
310
1833
M79.6
ICD-10 Finland
Pain in limb
1.4
18.3
1200
9610
R03AC02
ATC
salbutamol; inhalant
1.4
17.9
1465
12181
ZX120
NOMESCO Finland
Intravenous
1.8
17.9
262
1483
B01AC14
ATC
[U] anagrelide
+∞
17.7
17
*
N06AX11
ATC
mirtazapine; oral
1.4
17.6
923
7085
B04
ICPC
Blood symptom/complaint
5.6
17.4
33
60
D58.2
ICD-10 Finland
Other haemoglobinopathies
29.0
17.4
23
8
R03BB04
ATC
tiotropium bromide; inhalant
1.8
17.1
297
1769
B03XA02
ATC
darbepoetin alfa; parenteral
2.9
16.9
79
277
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
16.9
330
2030
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
16.7
954
7424
L03AA04, ,
ATC
16.4
16.5
26
16
J01MA12
ATC
levofloxacin; systemic
1.5
16.1
507
3504
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
16.0
606
4356
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
15.9
373
2406
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
15.8
904
7018
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
4.0
15.3
43
109
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
15.2
451
3074
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
15.0
326
2060
AA1AD
NOMESCO Finland
CT of head and brain
1.4
15.0
809
6206
ZXD05
NOMESCO Finland
Urgent procedure
1.4
15.0
776
5909
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
14.9
1156
9424
B01AB04
ATC
dalteparin; parenteral
2.1
14.8
145
715
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
14.8
702
5259
A10AE04
ATC
insulin glargine; parenteral
1.7
14.8
275
1669
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
14.8
324
2054
B01AC04
ATC
clopidogrel; oral
1.5
14.7
467
3230
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
14.7
323
2049
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
14.6
713
5368
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
14.6
231
1338
D73.5
ICD-10 Finland
Infarction of spleen
+∞
14.6
14
*
D72.1
ICD-10 Finland
Eosinophilia
80.5
14.6
16
*
J01MA02
ATC
ciprofloxacin; systemic
1.4
14.5
1048
8437
E83.1
ICD-10 Finland
Disorders of iron metabolism
5.4
14.5
28
52
WW200
NOMESCO Finland
Immunization
2.6
14.4
83
326
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
14.3
151
765
R53
ICD-10 Finland
Malaise and fatigue
1.4
14.3
664
4953
C09AA05
ATC
ramipril; oral
1.4
14.1
686
5159
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.9
672
5043
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
13.9
462
3223
189
Kela drug reimbursment
Imatinib
12.7
13.9
24
19
WX402
NOMESCO Finland
General anaesthesia
1.5
13.9
592
4342
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
13.8
179
974
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
13.8
359
2371
E66.8
ICD-10 Finland
Other obesity
2.0
13.8
150
769
R04.0
ICD-10 Finland
Epistaxis
1.8
13.8
216
1248
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.7
13.8
293
1842
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
13.6
152
786
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
4.3
13.6
34
79
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
13.3
508
3644
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
13.1
273
1705
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
13.1
1362
11540
R4190
NOMESCO Finland
Nutritional therapy
2.2
13.1
109
505
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
15.1
13.1
21
14
Z2446
NOMESCO Finland
Social worker
1.9
12.9
171
937
H02AB09
ATC
hydrocortisone; systemic
2.6
12.8
72
279
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
12.8
166
904
UJF32
NOMESCO Finland
Coloscopy
1.4
12.6
697
5342
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
12.6
259
1613
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
12.6
358
2411
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
12.3
12.6
22
18
2890X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Polycythaemia, secondary[ERYTHROCYTOSIS SECUNDARIA, NUD]
+∞
12.5
12
*
2898X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Other specified diseases of blood and blood-forming organs
+∞
12.5
12
*
WX002
NOMESCO Finland
Sedation and analgesia
1.5
12.5
501
3624
L01EA01
ATC
imatinib; oral
20.1
12.4
18
9
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.3
12.4
31
72
N02BE01
ATC
paracetamol; systemic, rectal
1.5
12.4
2485
23224
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
12.4
221
1326
C07AB02
ATC
metoprolol; systemic
1.4
12.3
525
3842
A10BJ06
ATC
semaglutide; parenteral
1.9
12.3
156
844
A10BK01
ATC
dapagliflozin; oral
1.7
12.2
223
1345
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
9.7
12.2
24
25
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
12.2
95
429
JN4BD
NOMESCO Finland
Extensive body CT
1.6
12.1
265
1676
TFP20
NOMESCO Finland
Cardiodefibrillation
1.7
12.1
208
1234
205
Kela drug reimbursment
Chronic hypertension
1.4
12.1
717
5559
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
3.8
11.9
35
92
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
3.0
11.9
50
166
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
11.8
117
580
J01CA04
ATC
amoxicillin; systemic
1.4
11.8
2188
20037
127
Kela drug reimbursment
Transplant complication
3.1
11.8
48
156
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
11.8
761
5977
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.7
11.7
215
1299
A10BH01
ATC
sitagliptin; oral
1.6
11.7
262
1668
E66.00
ICD-10 Finland
Metabolic syndrome
1.9
11.7
158
873
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
11.6
1899
17037
316
Kela drug reimbursment
Imatinib
30.1
11.6
15
5
3AC01, ,
NOMESCO Finland
3.8
11.6
35
94
S16
ICPC
Bruise/contusion
2.3
11.5
86
381
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
11.5
576
4333
M10.9
ICD-10 Finland
Gout, unspecified
1.7
11.5
202
1206
121
Kela drug reimbursment
Severe hypofunction of sexual glands
2.8
11.5
57
208
L04AD01
ATC
ciclosporin; systemic
2.8
11.4
55
197
N06AX12
ATC
bupropion; oral
1.8
11.4
165
932
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.5
11.2
68
274
R11
ICD-10 Finland
Nausea and vomiting
1.7
11.2
224
1384
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
4.3
11.2
28
65
J01FF01
ATC
clindamycin; systemic
1.4
11.2
695
5419
A91
ICPC
Abnormal result investigation NOS
1.8
11.1
156
873
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
11.1
173
999
C08CA05
ATC
nifedipine; systemic
1.8
11.0
157
882
D64.8
ICD-10 Finland
Other specified anaemias
2.7
11.0
59
224
B01AB10
ATC
tinzaparin; parenteral
1.6
11.0
289
1911
E0000UV, ,
ATC
1.3
11.0
1055
8771
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.9
10.8
131
698
207
Kela drug reimbursment
Chronic arrhythmias
1.5
10.8
430
3099
I50.0
ICD-10 Finland
Congestive heart failure
1.7
10.8
202
1227
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
2.9
10.8
48
165
R80
ICD-10 Finland
Isolated proteinuria
4.0
10.7
30
76
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.0
10.7
107
533
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
10.7
165
949
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
10.7
180
1063
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.8
10.7
149
832
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
10.6
491
3637
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.8
10.6
165
951
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.8
10.6
155
878
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
10.6
336
2316
C10AA01
ATC
simvastatin; oral
1.3
10.5
1106
9300
C10AA05
ATC
atorvastatin; oral
1.3
10.4
1157
9790
2387X
ICD-9 Finland
Neoplasm of uncertain behaviour of other and unspecified sites and tissues, Other lymphatic and haematopoietic tissues[STATUS LYMPHO- ET MYELOPROLIFERATIVUS NUD]
+∞
10.4
10
*
A46
ICD-10 Finland
Erysipelas
1.5
10.4
394
2812
S18
ICPC
Laceration/cut
1.3
10.4
1260
10786
R51.80
ICD-10 Finland
Headache
1.5
10.4
374
2645
N05BA04
ATC
oxazepam; oral
1.4
10.3
654
5104
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
12.1
10.3
18
15
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
10.2
1141
9658
N05CF01
ATC
zopiclone; oral
1.3
10.2
826
6691
N05CF02
ATC
zolpidem; oral
1.4
10.1
432
3154
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.7
10.1
177
1057
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.5
10.0
336
2340
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
10.0
337
2349
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
4.5
10.0
24
54
N07BA03
ATC
varenicline; oral
1.9
10.0
123
660
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
2.8
10.0
49
178
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.9
10.0
119
632
C01AA05
ATC
digoxin; systemic
1.6
9.9
208
1302
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
9.9
491
3680
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
9.9
518
3918
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
9.9
946
7834
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
9.8
113
592
L01XE01
ATC
[U] imatinib
12.2
9.8
17
14
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
5.2
9.8
20
39
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.9
9.8
119
635
J01DA01
ATC
[U] cefalexin
1.3
9.8
1593
14117
A10BK03
ATC
empagliflozin; oral
1.5
9.8
287
1943
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
9.7
460
3418
D69.1
ICD-10 Finland
Qualitative platelet defects
13.4
9.7
16
12
315
Kela drug reimbursment
Clopidogrel
3.3
9.4
35
108
D47.0
ICD-10 Finland
Histiocytic and mast cell tumours of uncertain and unknown behaviour
17.6
9.4
14
8
2899X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Unspecified diseases of blood and blood-forming organs
+∞
9.4
9
*
A10BJ02
ATC
liraglutide; parenteral
2.2
9.4
80
376
XF402
NOMESCO Finland
ECG with work load test
1.5
9.4
270
1822
E66.01
ICD-10 Finland
Obesity due to excess calories
1.6
9.4
225
1457
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
9.3
950
7917
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
9.3
243
1603
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
4.4
9.3
23
53
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
2.7
9.3
48
179
TK800
NOMESCO Finland
Hemodialysis
2.4
9.3
61
256
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
9.2
482
3644
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.3
9.2
603
4725
K92.1
ICD-10 Finland
Melaena
1.8
9.2
142
819
M54.5
ICD-10 Finland
Low back pain
1.3
9.2
920
7651
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
9.1
169
1025
D07AC01
ATC
betamethasone; topical
1.3
9.1
930
7750
L28
ICPC
Limited function/disability (L)
1.4
9.1
495
3765
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
9.1
480
3634
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.8
9.0
27
72
N03AX16
ATC
[U] pregabalin
1.4
9.0
580
4526
H02AB07
ATC
prednisone; oral
1.5
9.0
336
2390
C02AC05
ATC
moxonidine; oral
1.8
9.0
127
713
XG466
NOMESCO Finland
Sleep oxymetry
2.1
8.9
84
410
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
8.9
469
3546
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
2.0
8.9
97
500
WX892
NOMESCO Finland
Monitored bed care
1.6
8.8
201
1285
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.0
8.8
95
488
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
8.8
151
898
Z71.8
ICD-10 Finland
Other specified counselling
1.3
8.7
833
6871
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.6
8.7
210
1361
R02
ICPC
Shortness of breath/dyspnoea
1.4
8.7
348
2508
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.8
8.7
129
735
R42
ICD-10 Finland
Dizziness and giddiness
1.3
8.7
584
4587
L14
ICPC
Leg/thigh symptom/complaint
1.6
8.7
207
1338
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.7
814
6700
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
8.6
658
5263
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
2.3
8.6
62
272
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
4.8
8.6
19
40
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
16.3
8.5
13
8
I50
ICD-10 Finland
Heart failure
2.1
8.5
80
391
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
8.5
377
2768
D68.8
ICD-10 Finland
Other specified coagulation defects
3.2
8.5
32
100
D69.4
ICD-10 Finland
Other primary thrombocytopenia
27.6
8.5
11
*
ZXA10
NOMESCO Finland
Bilateral
1.4
8.4
442
3338
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.0
8.4
91
468
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
8.4
345
2499
SPAT1260
SPAT
Consultation of another employee
1.4
8.4
417
3123
N30.0
ICD-10 Finland
Acute cystitis
1.4
8.3
397
2950
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
8.3
8
*
D73.0
ICD-10 Finland
Hyposplenism
+∞
8.3
8
*
M10
ICD-10 Finland
Gout
1.8
8.3
120
678
J01FA10
ATC
azithromycin; systemic
1.3
8.3
1398
12337
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
8.2
1158
10005
A02BC05
ATC
esomeprazole; systemic
1.3
8.2
1024
8721
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
14.5
8.2
13
9
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
8.2
732
5978
OAB50, ,
SPAT
1.6
8.2
212
1397
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
2.2
8.2
64
291
SPAT1263
SPAT
Sampling
1.3
8.1
1012
8615
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.1
965
8170
R06AE07
ATC
cetirizine; oral
1.3
8.1
1057
9048
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
8.1
329
2377
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.1
8.1
70
332
I50.1
ICD-10 Finland
Left ventricular failure
1.7
8.1
129
752
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
8.0
717
5853
H02AB04
ATC
methylprednisolone; systemic
1.4
8.0
346
2528
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
2.8
8.0
37
131
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
7.2
8.0
18
25
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.9
257
1777
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.8
7.9
117
666
WX723
NOMESCO Finland
CPAP therapy
1.8
7.9
119
681
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.9
916
7725
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.9
692
5633
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
7.9
264
1838
A04AA01
ATC
ondansetron; systemic, rectal
1.6
7.9
195
1273
SPAT1377
SPAT
Polysomnography
2.0
7.8
82
417
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
7.8
274
1927
WX780
NOMESCO Finland
Remote monitoring CPAP
1.8
7.8
120
693
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
7.8
258
1794
C09CA01
ATC
losartan; oral
1.3
7.8
668
5424
Z01.7
ICD-10 Finland
Laboratory examination
1.4
7.7
409
3093
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
1.6
7.7
154
954
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.6
433
3311
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.6
707
5800
L17
ICPC
Foot/toe symptom/complaint
1.3
7.5
768
6369
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.0
7.5
81
417
N06AX16
ATC
venlafaxine; oral
1.4
7.5
328
2401
A03
ICPC
Fever
1.4
7.4
377
2830
L01AB01
ATC
busulfan; systemic
80.3
7.4
8
*
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
2.2
7.4
57
258
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.4
522
4122
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.8
7.4
115
666
L04AD02
ATC
tacrolimus; systemic
3.1
7.3
30
99
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.0
7.3
75
380
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
2.2
7.3
57
260
XW000, ,
SPAT
15.8
7.2
11
7
A02BC01
ATC
omeprazole; systemic
1.3
7.2
656
5359
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.6
7.2
164
1050
GD1AD
NOMESCO Finland
Thorax CT examination
1.6
7.2
165
1059
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
7.2
264
1873
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
7.1
1715
15629
L03AA02
ATC
filgrastim; parenteral
2.0
7.1
69
342
K99
ICPC
Cardiovascular disease other
2.0
7.1
71
356
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
2.0
7.1
75
384
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
7.1
371
2799
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
7.1
166
1071
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
7.0
242
1694
TKC20
NOMESCO Finland
Catheterisation of bladder
1.6
7.0
167
1080
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.3
7.0
50
219
I81
ICD-10 Finland
Portal vein thrombosis
4.2
7.0
18
43
TGC00
NOMESCO Finland
Bronchial lavation
2.1
7.0
66
324
A07EA06
ATC
budesonide; oral, local oral
1.9
7.0
89
485
A41.9
ICD-10 Finland
Sepsis, unspecified
1.9
7.0
87
471
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
6.9
443
3445
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
6.9
302
2211
J45.8
ICD-10 Finland
Mixed asthma
2.0
6.9
73
374
Z72.0
ICD-10 Finland
Tobacco use
2.0
6.9
66
326
SPAT1281
SPAT
Other administrative function
1.5
6.9
178
1174
A10AB05
ATC
insulin aspart; parenteral
1.5
6.9
187
1247
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.7
6.9
116
688
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
1.9
6.8
86
467
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
1.7
6.8
116
689
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
1.7
6.8
115
682
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.8
717
5961
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.5
6.8
215
1481
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
6.8
200
1358
N06AX21
ATC
duloxetine; oral
1.4
6.8
280
2030
R03AK08
ATC
formoterol and beclometasone; inhalant
1.7
6.7
108
632
E66.9
ICD-10 Finland
Obesity, unspecified
1.9
6.7
86
470
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
6.7
465
3660
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
2.3
6.7
50
224
R89.8
ICD-10 Finland
Abnormal findings in specimens from other organs, systems and tissues, other abnormal findings
22.6
6.7
9
*
L04AA06
ATC
mycophenolic acid; systemic
2.3
6.6
48
212
R03BB07
ATC
umeclidinium bromide; inhalant
3.1
6.6
27
89
I48.4
ICD-10 Finland
Atypical atrial flutter
3.6
6.6
21
59
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.7
6.6
122
743
J01AA02
ATC
doxycycline; systemic
1.2
6.6
2064
19268
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
6.5
422
3287
XF404
NOMESCO Finland
Ambulatory ECG
1.5
6.5
210
1453
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
6.5
385
2961
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.7
6.5
105
616
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1.8
6.5
93
527
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.3
6.4
562
4559
J45
ICD-10 Finland
Asthma
1.4
6.4
236
1673
K60
ICPC
Cardiovascular, Result test/procedure
3.2
6.4
24
75
N05CD07
ATC
temazepam; oral
1.4
6.4
279
2040
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
2.4
6.4
41
172
ZY010
NOMESCO Finland
Hospital outpatient
1.7
6.4
111
665
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.6
6.3
135
852
R4120
NOMESCO Finland
Occupational therapy
1.6
6.3
157
1028
C09AA02
ATC
enalapril; systemic
1.3
6.3
467
3708
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
2.4
6.3
40
167
B01AF02
ATC
apixaban; oral
1.4
6.3
344
2613
-50
ICPC
Medication/prescr/renewal
1.8
6.3
97
562
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.8
6.3
83
459
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
1.7
6.3
111
668
S29
ICPC
Skin symptom/complaint other
1.3
6.3
494
3955
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
6.3
6
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.6
6.2
155
1014
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.3
6.2
493
3949
N06AB10
ATC
escitalopram; oral
1.3
6.2
444
3507
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.0
6.2
66
340
J96.9
ICD-10 Finland
Respiratory failure, unspecified
3.2
6.1
23
72
A12BA01
ATC
potassium chloride; oral
1.7
6.1
104
619
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.6
6.1
135
860
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.6
6.1
118
727
TPX10
NOMESCO Finland
Implantation of vascular injection port
1.9
6.1
72
384
Z2445
NOMESCO Finland
Psychologist
1.8
6.1
81
449
N02BF01
ATC
gabapentin; oral
1.4
6.1
250
1811
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
6.1
1001
8726
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.6
6.0
33
128
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
1.9
6.0
67
350
JN4AD
NOMESCO Finland
Body CT examination
1.4
6.0
279
2063

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2275
12039
5.12
316.97
15.0
6.5
8.92
8.94
%
0.07
2186
11281
2273
12021
5.12
316.93
14.7
6.4
2.72
2.83
%
1.56
2185
11264
2272
12021
5.10
316.35
15.0
6.5
0.86
0.67
%
30.45
2184
11253
1237
4265
4.31
314.53
3.0
2.7
2.41
2.30
g/l
9.45
1164
3941
419
206
23.60
307.65
1.2
1.2
—
—
—
0
0
1035
2419
6.10
307.65
3.8
2.6
79.24
69.68
e9/l
9.80
714
1777
975
444
32.57
307.65
1.4
1.2
26.08
38.52
u/l
0.92
874
381
604
238
31.79
307.65
1.2
1.3
—
—
—
0
0
1221
3128
6.01
307.65
3.5
2.5
1.84
1.81
%
0.37
1102
2784
1206
3936
4.53
307.65
3.0
2.7
24.75
22.75
%
4.68
1144
3666
666
391
21.81
307.65
1.6
1.6
—
—
—
0
0
2280
12286
5.00
304.54
14.6
6.4
27.00
27.21
%
0.41
2204
11652
2239
12062
4.75
294.85
14.3
6.3
57.94
57.74
%
0.34
2167
11522
2349
13135
5.14
293.47
13.7
6.2
0.06
0.04
e9/l
33.22
2101
11227
2343
13101
5.10
292.05
13.8
6.2
0.65
0.59
e9/l
7.95
2096
11200
1253
4578
4.06
289.40
3.1
2.7
14.58
12.98
umol/l
9.84
1186
4272
2377
13566
5.16
284.76
14.9
6.4
0.21
0.19
e9/l
3.16
2157
11769
2355
13392
5.03
282.26
13.9
6.3
2.10
1.90
e9/l
1.74
2164
11735
2401
14749
4.64
236.10
19.7
9.3
4.66
4.17
e9/l
7.67
2165
12760
1466
6953
3.24
209.40
4.0
2.8
353.60
348.27
umol/l
1.13
1336
6125
685
2268
3.64
171.26
8.2
4.1
0.93
0.64
%
2.09
288
659
697
2373
3.55
166.53
8.3
4.3
1.20
0.81
%
2.60
287
701
93
22
43.64
155.88
1.3
1.4
—
—
—
0
0
663
2291
3.46
153.65
9.4
4.6
0.85
0.07
%
1.58
253
564
661
2282
3.46
153.39
8.3
4.4
0.14
0.11
%
0.56
254
611
1871
11369
2.82
152.35
22.5
11.6
0.03
0.00
e9/l
3.85
1575
9264
350
775
5.00
149.48
3.0
2.4
3.28
3.63
g/l
4.73
339
736
2096
13836
2.86
139.43
10.2
6.6
12.33
11.78
umol/l
1.21
2043
13232
1848
11713
2.59
128.79
4.5
3.1
147.77
133.68
ug/l
0.89
1723
10899
1125
5656
2.62
128.48
9.6
4.7
—
—
—
0
0
432
1260
3.85
127.92
2.4
1.8
1.20
1.55
g/l
10.96
380
1089
222
441
5.37
106.64
3.6
3.4
4.66
4.24
e9/l
1.16
222
441
244
540
4.84
103.35
4.2
3.3
59.02
58.57
%
0.20
244
540
1351
7980
2.30
101.81
6.5
4.2
7.39
7.40
ph
5.08
1001
5740
327
939
3.80
98.01
4.5
3.7
50.88
60.48
mg/l
0.50
291
803
326
940
3.78
97.10
4.5
3.7
46.39
74.06
mg/l
0.88
291
807
152
234
6.80
94.79
1.1
1.1
—
—
—
0
0
301
836
3.90
94.54
4.5
3.5
3.10
3.18
ratio
0.02
166
481
567
2313
2.80
94.51
3.6
2.8
66.62
66.38
g/l
0.29
516
2143
293
808
3.92
92.92
3.4
3.1
1.39
1.59
mg/l
4.12
272
735
1199
6993
2.22
90.26
3.0
2.3
3.73
2.82
mg/l
9.74
1037
6033
700
3239
2.53
90.10
5.1
3.3
4.92
4.62
e9/l
0.52
596
2797
340
1067
3.48
88.86
4.2
2.5
2.91
2.92
g/l
0.08
315
979
1897
13316
2.23
88.43
9.8
7.5
1.21
1.21
mmol/l
0.59
1596
11531
2492
19741
2.86
87.59
15.3
8.3
82.64
79.56
u/l
2.74
2415
18757
1748
11978
2.16
85.26
9.3
6.8
1.22
1.21
mmol/l
3.95
1636
11058
348
1138
3.34
85.06
4.2
2.5
3.72
3.73
g/l
0.02
324
1050
348
1139
3.34
84.94
4.2
2.5
6.80
7.38
g/l
8.66
324
1050
348
1139
3.34
84.94
4.2
2.5
4.09
4.20
g/l
1.44
323
1051
423
1556
3.01
84.69
2.1
1.9
1.45
1.34
g/l
0.33
392
1433
491
1971
2.79
83.63
2.9
2.9
10.26
10.80
g/l
1.58
452
1811
311
974
3.46
81.30
4.2
2.5
10.70
10.31
g/l
0.62
286
879
55
20
28.01
81.22
1.1
1.1
—
—
—
0
0
1721
11884
2.10
80.14
7.2
5.2
35.72
35.55
g/l
0.63
1626
11165
640
3034
2.42
76.80
4.1
2.7
7.69
8.30
umol/l
0.39
573
2703
176
384
4.81
75.50
3.2
2.0
0.98
0.90
%
0.93
110
264
1120
6751
2.07
73.67
6.5
4.2
85.12
88.50
%
4.29
1083
6611
712
3666
2.25
69.71
6.9
6.2
1.04
1.04
mmol/l
0.27
677
3404
210
589
3.77
64.51
1.7
1.6
—
—
—
0
0
2306
18804
2.10
56.21
5.7
4.4
12.53
12.28
mm/h
0.28
2172
17589
1990
15434
1.92
55.92
7.7
5.3
6.79
6.76
mmol/l
0.26
1933
14714
1615
11805
1.83
53.88
2.6
2.2
93.23
95.64
pmol/l
1.30
980
6231
1134
7451
1.86
53.48
4.1
3.4
0.55
0.42
e6/l
0.76
860
5487
1152
7699
1.82
50.70
2.1
1.7
19.78
20.15
nmol/l
0.39
1015
6479
1662
12390
1.80
50.56
20.8
15.8
1.30
1.27
inr
1.71
1422
10334
263
997
2.80
48.80
2.8
2.0
21.24
21.28
s
0.04
238
895
427
2039
2.28
48.53
4.6
4.0
—
—
—
0
0
1161
7861
1.80
48.29
11.6
6.1
—
—
—
0
0
1245
8649
1.77
47.09
4.2
3.5
70.65
82.24
e6/l
0.20
964
6635
152
423
3.74
47.08
6.8
3.3
1.39
1.41
%
0.03
128
380
908
5750
1.84
46.81
2.2
1.8
1.22
1.25
mg/l
0.13
724
4463
832
5132
1.87
46.61
3.2
3.0
519.47
533.57
mosm/kgh2o
1.10
730
4506
1361
9740
1.75
46.05
5.2
4.1
109.29
100.49
e6/l
0.16
1001
6946
751
4556
1.87
43.91
4.4
3.3
0.82
0.82
mmol/l
0.20
722
4305
148
426
3.61
43.60
1.4
1.5
153.22
151.39
au/ml
0.07
54
130
159
480
3.45
43.55
1.4
1.4
23.61
17.08
u/ml
—
5
14
156
473
3.43
42.43
1.4
1.5
—
—
—
0
0
421
2105
2.17
42.39
4.3
3.9
1.22
1.23
mmol/l
0.81
366
1820
692
4148
1.88
41.71
3.0
2.1
30.93
29.69
s
5.26
666
4042
503
2724
2.02
40.85
1.6
1.6
—
—
—
0
0
787
4946
1.81
40.56
1.8
1.5
2.54
2.51
g/l
0.14
534
3035
1230
8778
1.70
40.32
4.4
3.2
34.32
35.74
u/l
0.26
1180
8286
603
3528
1.90
38.85
1.5
1.3
450.76
484.14
titre
0.19
119
792
907
6017
1.74
38.41
3.3
2.7
4.43
5.21
e6/l
1.55
821
5502
72
131
5.61
37.87
2.0
1.6
—
—
—
0
0
572
3326
1.90
37.41
1.6
1.6
—
—
—
0
0
175
614
2.97
37.28
4.6
3.9
—
—
—
0
0
364
1804
2.16
37.22
1.4
1.5
—
—
—
0
0
1156
8273
1.66
36.41
3.7
3.2
1687.24
1401.08
ng/l
1.26
968
7128
714
4507
1.77
35.53
1.9
1.8
1130.20
1162.47
nmol/l
0.39
525
3419
105
281
3.84
34.39
2.2
2.1
—
—
—
0
0
159
560
2.95
33.62
5.6
4.5
2.98
2.65
mmol/l
0.54
112
375
136
442
3.18
33.04
1.3
1.3
240.20
259.03
u/ml
0.33
83
272
184
711
2.70
32.69
3.9
3.4
3.52
1.97
index
0.56
111
363
1055
7540
1.63
32.39
6.1
4.4
—
—
—
0
0
112
329
3.50
31.98
2.5
2.3
1.16
1.39
g/24h
0.38
83
194
410
2242
1.97
31.82
1.5
1.4
—
—
—
0
0
630
3948
1.76
31.67
1.8
1.8
—
—
—
0
0
1693
13628
1.58
30.79
4.3
4.0
0.01
0.01
estimate
0.49
483
2660
1664
13377
1.57
30.14
4.2
3.9
0.00
0.00
estimate
0.50
513
2808
1680
13543
1.57
30.00
4.3
4.0
4.95
3.99
estimate
0.10
520
2865
77
184
4.27
29.43
1.8
2.3
38.80
38.52
%
0.05
77
184
431
2460
1.88
29.26
2.6
2.2
370.09
378.24
nmol/l
0.39
407
2272
92
252
3.74
29.16
6.6
3.4
—
—
—
0
0
172
697
2.56
27.74
1.3
1.2
—
—
—
0
0
1204
9145
1.54
27.07
4.8
4.2
13.14
9.08
mg/mmol
1.82
770
5759
164
662
2.57
26.66
1.6
1.4
8.52
9.09
u/l
0.24
123
542
178
752
2.46
26.28
2.0
1.6
0.24
0.24
g/l
0.07
164
718
1202
9195
1.52
25.76
3.8
3.5
2.35
2.35
mmol/l
0.85
1086
8345
432
2569
1.80
25.46
8.6
7.7
10.07
10.05
mmol/l
0.02
409
2467
646
4305
1.64
25.11
3.8
3.2
2.26
2.07
e6/l
0.19
310
2094
2652
24387
2.02
24.93
28.8
16.7
21.58
24.89
mg/l
6.84
2372
20226
179
779
2.38
24.75
1.9
1.6
1.20
1.19
g/l
0.12
166
744
1171
8982
1.51
24.37
4.0
3.6
77.29
49.90
mg/l
2.07
794
5804
1217
9427
1.50
24.05
4.0
3.5
7.72
7.58
mmol/l
0.47
998
7984
205
959
2.22
23.93
1.2
1.2
—
—
—
0
0
426
2583
1.76
23.37
2.7
2.6
35.39
58.08
u/l
0.65
373
2206
1932
16493
1.51
23.31
5.7
4.8
226.96
1733.74
e6/l
2.72
24
233
1096
8360
1.50
23.07
2.3
2.2
194.47
228.02
u/l
0.55
1024
7936
409
2460
1.77
23.05
11.5
9.7
—
—
—
0
0
158
672
2.43
22.98
3.5
3.0
7.94
8.09
kpa
0.49
153
660
420
2559
1.75
22.61
9.7
8.4
1.44
1.33
mmol/l
0.97
415
2518
2280
20272
1.58
21.98
40.3
20.4
14.70
13.66
%
86.18
2265
19982
320
1817
1.86
21.76
4.1
3.7
5.30
5.16
kpa
1.96
302
1748
432
2680
1.72
21.75
2.5
2.2
0.21
0.21
g/l
0.60
402
2508
313
1768
1.86
21.63
4.1
3.7
7.41
7.42
ph
0.30
264
1472
88
285
3.15
21.56
7.9
3.0
61.39
58.42
%
0.63
67
246
955
7160
1.50
21.49
4.0
3.4
0.00
0.13
estimate
0.62
434
2189
554
3690
1.62
21.16
1.3
1.3
—
—
—
0
0
274
1494
1.92
21.09
3.0
3.6
4.44
4.46
pmol/l
0.18
236
1334
1437
11701
1.45
21.02
3.0
2.4
76.69
77.66
nmol/l
0.65
1297
10548
133
546
2.50
20.89
1.2
1.2
—
—
—
0
0
1264
10118
1.44
19.85
4.7
3.9
32.99
105.69
ng/l
1.01
976
7335
109
417
2.68
19.77
1.1
1.1
—
—
—
0
0
1087
8480
1.45
19.50
4.4
2.5
—
—
—
0
0
110
426
2.64
19.48
2.6
1.8
1.61
1.69
mmol/l
0.47
105
417
474
3097
1.63
19.43
2.1
1.8
—
—
—
0
0
1271
10220
1.43
19.29
2.4
2.2
—
—
—
0
0
497
3291
1.62
19.28
9.7
8.5
11.30
12.23
kpa
3.40
487
3163
41
83
5.00
19.24
1.0
1.1
—
—
—
0
0
496
3291
1.61
19.07
9.8
8.5
5.19
5.12
kpa
0.78
487
3165
109
425
2.63
19.05
1.1
1.1
—
—
—
0
0
78
254
3.13
18.97
2.3
2.4
57.07
42.20
iu/ml
—
10
31
656
4683
1.52
18.16
3.8
3.1
1.13
1.04
e6/l
0.13
330
2483
2148
19118
1.48
18.05
5.1
4.4
15.08
14.85
pmol/l
4.03
1956
17517
731
5362
1.49
17.67
3.5
3.0
2.45
2.45
mmol/l
0.01
649
4838
489
3288
1.59
17.67
9.9
8.6
7.42
7.42
ph
0.27
261
1783
156
741
2.17
17.53
1.2
1.2
586.00
1283.33
titre
—
5
21
486
3269
1.58
17.52
9.8
8.5
0.93
0.96
mmol/l
0.05
418
2701
156
744
2.16
17.35
1.2
1.2
521.67
104.71
titre
—
6
68
57
162
3.57
17.21
1.8
2.0
74.15
71.67
%
0.43
52
154
2675
25111
1.84
17.17
32.2
20.0
139.50
139.69
mmol/l
3.52
2644
24638
716
5278
1.47
16.74
5.0
4.0
557.00
607.27
ng/l
0.05
582
4207
66
210
3.19
16.71
1.9
2.3
1298.63
1215.69
e6/l
0.22
54
190
2471
22759
1.58
16.59
6.5
5.4
1.94
1.93
mu/l
0.14
2298
20997
2676
25164
1.82
16.50
33.8
20.1
3.99
3.98
mmol/l
1.83
2639
24646
1310
10808
1.39
16.13
3.5
3.5
6.08
6.22
ph
4.80
665
6048
1053
8383
1.40
16.01
3.2
2.7
53.08
70.26
u/l
1.13
978
7782
92
363
2.58
15.75
1.6
1.4
74.49
84.26
mu/l
0.13
82
329
28
48
5.88
15.71
2.0
2.1
1.28
0.16
e9/l
0.48
17
18
52
148
3.56
15.70
2.2
2.7
262.07
225.13
e6/l
0.28
42
132
1909
16809
1.40
15.55
4.4
3.4
59.22
51.43
u/l
3.04
1810
15781
544
3849
1.51
15.42
2.2
2.1
—
—
—
0
0
438
2956
1.57
15.42
10.2
8.9
94.22
95.61
%
4.03
430
2854
463
3195
1.53
14.71
1.6
1.5
—
—
—
0
0
981
7804
1.39
14.65
3.5
3.3
—
—
—
0
0
949
7522
1.39
14.44
4.4
4.1
0.00
0.00
estimate
0.22
478
2592
445
3056
1.54
14.43
1.4
1.4
—
—
—
0
0
189
1035
1.88
14.31
2.0
1.8
7.75
7.63
iu/ml
0.02
37
245
42
111
3.82
14.13
1.5
7.0
5508.38
61.54
mg/l
0.49
34
80
325
2090
1.63
13.96
4.5
4.0
94.05
92.42
ng/l
0.11
281
1811
134
657
2.09
13.91
2.1
2.1
15.77
12.17
mg/l
1.30
122
607
414
2825
1.54
13.79
4.8
3.6
5.80
5.84
kpa
0.33
403
2748
49
147
3.37
13.69
1.9
2.5
657.00
582.72
e6/l
0.28
35
123
84
340
2.51
13.68
1.3
1.4
345.00
307.95
pmol/l
0.42
73
291
831
6510
1.39
13.35
4.5
2.4
—
—
—
0
0
1413
12039
1.34
13.12
4.6
2.8
—
—
estimate
—
0
0
32
73
4.42
13.08
1.0
1.0
—
—
—
0
0
29
61
4.79
13.06
1.2
1.1
1010.00
884.62
titre
—
10
13
414
2860
1.52
12.98
5.0
3.7
7.37
7.38
ph
0.83
227
1615
2482
23148
1.50
12.93
5.4
4.4
1.46
1.30
mmol/l
15.98
2310
21254
486
3477
1.48
12.85
1.4
1.3
—
—
—
0
0
401
2758
1.53
12.83
4.8
3.7
1.33
1.90
mmol/l
1.93
350
2391
39
105
3.75
12.81
29.6
29.2
118.53
121.28
ug/l
0.09
33
84
24
44
5.49
12.58
1.2
1.4
—
—
—
0
0
138
712
1.99
12.49
2.5
2.0
202.44
207.64
pmol/l
0.22
131
676
360
2435
1.55
12.41
4.3
2.4
13.49
13.46
nmol/l
0.02
331
2200
81
338
2.44
12.39
1.4
1.3
0.21
0.24
nmol/l
0.24
58
273
130
662
2.01
12.21
2.6
2.2
147.19
129.02
g/l
7.46
107
515
164
906
1.86
12.11
2.5
2.0
35.85
39.74
nmol/l
1.47
159
873
64
241
2.69
12.09
4.3
3.3
16.71
11.20
index
3.07
42
139
2503
23460
1.49
11.94
8.3
6.6
39.86
39.54
mmol/mol
0.87
2348
21939
89
394
2.30
11.94
1.4
1.3
0.16
0.36
nmol/l
—
7
27
395
2750
1.51
11.89
11.3
9.4
126.94
121.91
g/l
3.18
390
2684
177
1011
1.80
11.73
2.8
2.2
531.89
480.25
ug/l
0.10
168
960
88
391
2.29
11.71
1.5
1.2
5.12
4.69
u/ml
0.10
49
175
1274
10811
1.32
11.65
2.2
2.0
1.53
1.37
mmol/l
6.51
1038
9101
32
80
4.03
11.65
1.1
1.0
—
—
—
0
0
30
72
4.20
11.52
1.3
1.1
—
—
—
0
0
55
198
2.81
11.33
1.1
1.2
194.00
189.71
titre
—
10
35
83
366
2.31
11.26
1.2
1.2
109.40
115.32
%
0.89
72
339
28
65
4.34
11.22
1.1
1.1
—
—
—
0
0
884
7150
1.34
11.19
3.3
3.0
0.00
0.01
—
10
165
82
364
2.29
10.96
1.3
1.2
—
—
—
0
0
45
150
3.03
10.65
1.6
3.0
37.24
42.60
%
0.46
11
84
67
278
2.44
10.43
2.8
2.3
—
—
—
0
0
2693
25782
1.62
10.17
23.2
12.4
28.83
26.80
u/l
3.98
2637
25055
285
1914
1.54
10.10
13.1
10.7
92.61
93.94
%
2.42
285
1905
131
722
1.85
9.79
2.0
1.7
276.62
283.58
mu/l
0.12
123
662
59
239
2.50
9.69
1.3
1.4
—
—
—
0
0
29
79
3.70
9.43
1.2
1.1
—
—
—
0
0
75
343
2.22
9.39
1.6
1.5
—
—
—
0
0
75
343
2.22
9.39
1.6
1.5
—
—
—
0
0
75
343
2.22
9.39
1.6
1.5
—
—
—
0
0
75
343
2.22
9.39
1.6
1.5
—
—
—
0
0
1180
10113
1.28
9.32
4.2
3.9
0.07
0.08
estimate
0.04
449
2296
160
952
1.72
9.25
1.6
1.4
19.91
28.15
iu/l
3.54
134
817
2549
24206
1.44
9.11
6.4
5.2
1.29
1.45
mmol/l
70.95
2395
22444
2512
23800
1.41
9.02
6.2
5.3
6.14
5.99
mmol/l
5.38
2307
21833
2593
24730
1.46
8.78
7.3
6.0
2.47
2.68
mmol/l
27.76
2447
22986
84
413
2.06
8.77
1.7
1.7
0.81
0.83
g/l
0.04
63
327
44
162
2.74
8.77
1.4
1.3
—
—
—
0
0
688
5531
1.32
8.72
1.8
1.8
34871317.63
24870111.84
pmol/l
0.20
542
4604
705
5695
1.31
8.61
1.4
1.3
1.42
1.49
u/ml
0.07
178
1515
187
1182
1.62
8.60
1.3
1.2
—
—
—
0
0
140
820
1.74
8.58
1.5
1.4
286.38
277.12
ug/g
0.19
82
493
2557
24354
1.42
8.43
6.5
5.3
4.27
4.59
mmol/l
52.09
2422
22733
47
183
2.59
8.42
1.6
2.2
18.01
18.13
nmol/l
0.03
47
167
2702
26025
1.56
8.29
38.3
21.9
82.57
79.42
umol/l
4.71
2679
25726
424
3189
1.39
8.28
2.5
2.5
135.61
140.34
ug/g
0.09
347
2579
326
2347
1.44
8.18
3.8
3.0
4.96
4.51
kpa
2.21
315
2282
99
530
1.90
8.15
1.3
1.4
55.75
61.24
mmol/l
0.84
84
426
12
7
17.21
8.07
1.0
1.0
—
—
—
0
0
12
7
17.21
8.07
1.0
1.0
—
—
—
0
0
12
7
17.21
8.07
1.0
1.0
—
—
—
0
0
32
104
3.10
7.97
1.3
1.6
—
—
—
0
0
303
2162
1.45
7.97
3.2
3.1
240.80
200.57
ng/l
0.94
277
1982
77
384
2.03
7.78
1.1
1.1
1.52
1.52
g/l
0.02
69
346
85
441
1.96
7.69
2.0
2.1
4.67
5.01
mmol/24h
0.41
78
382
55
241
2.31
7.68
1.3
1.3
2.96
2.92
g/l
0.04
35
173
55
241
2.31
7.68
1.3
1.3
7.99
6.94
g/l
0.42
36
174
55
241
2.31
7.68
1.3
1.3
0.32
0.39
g/l
1.02
36
173
113
649
1.77
7.45
3.6
2.4
60.53
62.02
%
0.27
113
644
11
7
15.77
7.22
1.0
1.0
—
—
—
0
0
11
7
15.77
7.22
1.0
1.0
—
—
—
0
0
41
162
2.55
7.17
2.4
2.3
17.39
16.34
%
0.83
41
162
44
182
2.44
7.01
1.3
1.1
—
—
—
0
0
61
294
2.10
6.80
5.4
5.6
7.56
7.43
mmol/l
0.13
55
250
151
963
1.60
6.75
1.2
1.2
0.20
1.12
u/ml
—
6
68
112
664
1.71
6.65
1.2
1.1
—
—
—
0
0
166
1087
1.56
6.64
1.4
1.7
0.27
0.33
mg/l
0.59
67
529
62
304
2.06
6.61
1.2
1.1
—
—
—
0
0
44
194
2.29
6.13
1.8
1.4
—
—
—
0
0
143
926
1.57
6.03
1.5
1.6
37.07
16.21
u/ml
1.11
23
200
44
196
2.26
5.99
1.3
1.1
—
—
—
0
0
231
1654
1.43
5.98
1.4
1.3
176.49
214.32
u/ml
0.34
213
1539
60
306
1.98
5.79
1.6
1.5
0.25
0.31
nmol/l
0.51
44
234
191
1328
1.47
5.78
1.3
1.2
—
—
—
0
0
26
94
2.78
5.46
3.4
2.5
0.60
0.61
mmol/l
0.20
26
94
17
48
3.56
5.32
2.8
2.7
14.79
14.80
ml/dl
0.00
17
43
92
552
1.69
5.30
1.3
1.2
21.43
49.55
u/ml
—
7
57
821
7092
1.22
5.29
1.5
1.4
—
—
—
0
0
179
1254
1.46
5.24
4.0
3.8
—
—
—
0
0
55
284
1.95
5.16
1.2
1.1
—
—
—
0
0
66
363
1.84
5.13
2.3
2.6
—
—
—
0
0
111
705
1.60
5.13
1.4
1.2
10.99
8.94
u/ml
0.16
12
104
32
134
2.40
5.05
1.2
1.2
1.08
1.07
ratio
0.23
27
115
110
703
1.59
4.96
1.4
1.2
37.53
2.92
u/ml
—
9
58
41
193
2.14
4.94
1.1
1.1
—
—
—
0
0
96
594
1.64
4.94
1.4
1.4
657.79
1604.47
e6/l
0.63
77
459
14
28
5.02
4.94
1.4
1.2
55.44
146.31
ug/l
—
9
13
95
587
1.64
4.92
1.4
1.3
13.51
40.72
e6/l
1.03
72
427
21
72
2.93
4.87
1.6
1.2
20.33
14.45
%
—
6
11
215
1584
1.39
4.77
1.3
1.2
143.95
136.05
u/ml
0.10
67
585
24
90
2.68
4.74
1.9
1.8
30.37
28.57
%
0.19
24
90
557
4669
1.24
4.74
1.3
1.3
33.48
33.28
iu/ml
0.01
162
1436
140
956
1.49
4.69
3.8
3.8
24.88
24.86
mmol/l
0.03
120
886
92
572
1.63
4.67
3.6
3.5
0.78
0.83
nmol/l
0.63
80
467
354
2822
1.29
4.60
3.4
4.3
4.39
18.05
ug/l
3.47
288
2316
29
122
2.39
4.56
3.2
2.9
—
—
—
0
0
259
1983
1.34
4.51
1.2
1.2
—
—
—
0
0
89
557
1.62
4.42
1.4
1.3
—
—
—
0
0
96
618
1.57
4.25
4.6
2.7
35.72
35.74
umol/l
0.00
89
557
53
291
1.84
4.20
1.4
1.5
—
—
—
0
0
157
1123
1.42
4.17
2.0
1.9
1.44
2.08
ug/l
0.39
136
994
21
79
2.67
4.15
1.5
1.6
71.19
524.43
nmol/24h
0.68
21
79
11
21
5.25
4.14
1.9
2.2
—
—
—
0
0
38
188
2.03
4.08
1.9
2.8
29.56
31.43
mg/l
0.10
25
142
27
116
2.34
4.08
1.4
1.2
70.00
71.88
%
—
6
17
18
63
2.87
4.06
1.8
1.6
—
—
—
0
0
2712
26500
1.36
4.03
47.9
25.3
326.91
247.59
e9/l
122.79
2678
25964
2712
26505
1.36
3.98
47.7
25.2
93.19
91.27
fl
25.91
2693
26208
2712
26507
1.35
3.96
47.6
25.1
30.83
30.39
pg
9.59
2693
26208
2712
26508
1.35
3.95
47.8
25.2
4.63
4.49
e12/l
14.78
2669
25885
2712
26508
1.35
3.95
48.9
25.8
42.11
40.60
%
11.30
2693
26198
2712
26513
1.35
3.90
47.9
25.3
7.99
6.73
e9/l
25.02
2670
25886
2712
26514
1.35
3.89
48.3
25.4
139.54
135.56
g/l
18.04
2694
26223
33
158
2.10
3.88
1.5
1.4
1.82
1.24
nmol/l
1.33
24
115
39
200
1.96
3.82
2.5
2.2
605.72
630.80
ml
0.16
25
127
167
1233
1.38
3.72
1.1
1.1
—
1.49
—
0
12
100
673
1.50
3.67
1.5
2.0
2.47
12.51
iu/l
0.61
30
269
510
4347
1.21
3.64
1.3
1.3
11.51
11.00
u/ml
0.06
173
1693
19
73
2.61
3.63
1.4
1.2
—
—
—
0
0
21
85
2.48
3.63
5.0
4.6
—
—
—
0
0
32
156
2.06
3.61
2.3
2.1
474.15
485.17
min
0.15
20
109
1934
20288
0.86
3.54
42.2
21.4
330.29
332.44
g/l
13.08
1925
20166
25
111
2.26
3.54
1.2
1.3
141.76
174.86
mmol/24h
1.28
25
111
16
57
2.82
3.52
1.6
1.1
—
—
—
0
0
194
1488
1.33
3.39
3.7
2.7
0.59
0.62
%
0.59
194
1481
135
1832
0.72
3.34
1.7
1.8
3.35
3.49
mmol/l
0.85
104
1298
161
1205
1.36
3.32
1.1
1.1
—
—
—
0
0
140
1031
1.38
3.21
2.5
3.5
295.85
4145.16
u/ml
0.83
118
892
90
612
1.49
3.19
1.3
1.2
3.82
3.78
mmol/l
0.12
85
578
11
29
3.80
3.18
1.1
1.0
0.02
0.14
u/ml
0.58
11
29
48
281
1.72
3.16
1.4
1.6
—
—
—
0
0
61
381
1.61
3.15
2.3
2.5
—
—
—
0
0
10
25
4.01
3.08
1.9
3.0
0.30
0.60
u/field
—
10
25
37
203
1.83
3.03
1.7
1.4
157.36
161.21
pmol/l
0.05
37
203
630
5557
1.17
3.02
3.4
3.2
0.67
0.76
ug/l
2.78
414
3625
9
21
4.30
2.99
1.3
1.0
—
—
—
0
0
222
1772
1.27
2.92
2.5
2.4
19.89
20.64
au/ml
0.03
18
180
18
76
2.38
2.89
1.3
1.3
29.56
29.52
s
0.00
18
76
201
2512
0.79
2.79
2.1
2.0
3.90
3.53
ratio
2.40
168
1986
1026
9426
1.14
2.75
4.2
3.2
—
—
—
0
0
6
10
6.01
2.70
1.2
1.6
1.53
1.36
%
—
6
10
157
2014
0.77
2.69
1.4
1.4
—
—
—
0
0
8
19
4.22
2.67
1.3
1.0
—
—
—
0
0
8
19
4.22
2.67
1.3
1.0
—
—
—
0
0
221
1784
1.26
2.67
4.1
3.1
133.04
129.43
g/l
1.01
211
1726
34
190
1.80
2.66
1.6
1.4
13.56
13.25
u/l
0.10
34
181
81
562
1.45
2.65
1.8
2.2
1.08
0.84
nmol/l
2.12
70
472
9
25
3.61
2.57
1.3
1.0
—
—
—
0
0
58
380
1.54
2.51
1.3
1.5
31.07
31.96
g/l
0.22
51
342
48
302
1.60
2.47
1.3
1.9
—
—
—
0
0
201
1622
1.26
2.45
1.4
1.3
37.67
54.22
au/ml
0.69
16
115
1005
9275
1.13
2.45
5.3
5.5
2.67
3.19
ug/l
0.31
891
8391
41
249
1.66
2.43
1.3
1.2
—
—
—
0
0
35
204
1.72
2.41
1.5
1.3
0.47
1.17
u/ml
0.88
21
114
208
1694
1.25
2.35
1.8
1.8
—
—
—
0
0
24
126
1.91
2.30
1.6
1.4
5.17
4.21
%
—
6
24
24
127
1.90
2.26
2.8
3.1
36.22
23.55
mu/l
0.68
24
122
87
633
1.39
2.24
2.8
2.3
133.96
115.01
ug/min
0.12
48
379
29
164
1.78
2.23
1.6
1.7
—
—
—
0
0
16
73
2.20
2.21
1.1
1.2
10.05
8.65
pmol/l
—
6
31
44
280
1.58
2.20
1.4
1.5
—
—
—
0
0
13
54
2.41
2.19
1.1
1.0
—
—
—
0
0
38
234
1.63
2.17
1.7
1.6
26.52
28.96
%
0.14
17
145
7
19
3.69
2.15
1.1
1.5
—
—
—
0
0
74
531
1.40
2.08
4.7
3.3
—
—
—
0
0
42
269
1.57
2.06
2.9
2.3
—
—
—
0
0
6
15
4.01
2.04
2.3
4.2
—
—
—
0
0
22
118
1.87
2.01
1.4
2.7
66.88
108.04
umol/l
—
8
70
120
936
1.29
1.98
3.7
3.3
846.94
301.19
mg/l
0.83
70
408
60
419
1.44
1.97
1.1
1.1
19.48
18.04
au/ml
—
8
96
87
648
1.35
1.97
1.2
1.3
161.45
229.40
miu/ml
1.11
37
280
8
27
2.97
1.93
1.1
1.1
—
—
—
0
0
13
58
2.25
1.90
1.5
1.7
—
—
—
0
0
45
299
1.51
1.90
1.4
1.4
170254.78
97232.31
e6/l
0.40
27
166
37
236
1.58
1.87
1.0
1.1
311.09
287.90
mg/l
1.07
32
212
46
309
1.50
1.85
1.3
1.3
278.82
277.89
mosm/kgh2o
0.08
34
226
5
12
4.17
1.82
1.0
1.1
—
—
—
0
0
32
201
1.60
1.74
1.3
1.2
—
—
—
0
0
30
186
1.62
1.72
1.0
1.1
57.26
42.64
mg/l
0.55
19
152
233
1988
1.19
1.72
2.6
2.7
5.96
6.07
ph
1.15
153
1347
36
234
1.55
1.70
1.3
1.2
—
—
—
0
0
43
291
1.48
1.69
1.4
1.4
—
—
—
0
0
12
55
2.19
1.67
2.5
2.7
4.08
67.78
ug/l
0.50
12
55
20
112
1.79
1.64
2.4
1.7
41.70
39.75
g/l
0.86
20
112
41
278
1.48
1.61
1.2
1.1
—
—
—
0
0
543
5944
0.89
1.60
4.1
4.2
1.02
1.27
kg/l
0.50
383
3968
49
347
1.42
1.55
1.4
1.4
1635.88
4271.07
e6/l
0.50
34
237
59
433
1.37
1.53
1.2
1.1
210.33
95.65
iu/ml
0.40
12
91
26
162
1.61
1.49
1.1
1.7
2.45
4.89
ug/l
0.80
17
136
48
342
1.41
1.48
4.0
3.2
—
—
—
0
0
44
310
1.43
1.45
1.8
1.6
65.57
61.98
%
0.27
23
195
5
16
3.13
1.44
2.0
1.1
—
—
—
0
0
56
413
1.36
1.43
1.1
1.1
—
—
—
0
0
56
413
1.36
1.43
1.1
1.1
—
—
—
0
0
286
2523
1.15
1.42
2.5
2.2
0.04
0.01
estimate
0.52
67
518
155
1301
1.20
1.41
2.5
2.2
0.00
0.66
estimate
0.51
51
383
32
213
1.51
1.40
4.8
5.3
64.60
55.02
u/ml
—
10
68
160
1348
1.20
1.40
2.2
2.4
—
—
—
0
0
5
17
2.94
1.36
1.6
1.0
4.42
5.26
nmol/l
—
5
17
22
135
1.63
1.35
1.5
1.2
0.64
0.54
ratio
—
8
78
59
776
0.76
1.34
1.0
1.1
0.56
0.66
ratio
0.96
11
98
15
83
1.81
1.31
1.2
1.4
14.22
13.61
g/l
—
10
67
131
1092
1.21
1.30
2.9
2.6
—
—
—
0
0
8
34
2.36
1.29
1.5
1.4
—
—
—
0
0
25
161
1.56
1.28
2.1
2.2
2.49
1.97
ug/l
0.40
20
137
61
465
1.32
1.28
1.2
1.1
1.45
2.05
u/ml
0.26
37
251
10
48
2.09
1.27
2.0
2.3
12.96
18.76
umol/l
—
10
48
22
138
1.60
1.26
6.5
7.0
9.65
152.81
ug/l
0.60
13
87
287
2558
1.14
1.24
4.3
4.3
7.36
7.35
ph
0.15
206
1823
20
315
0.63
1.24
1.4
1.5
57.25
61.19
ug/l
0.16
13
257
9
45
2.00
1.23
1.0
1.1
—
—
—
0
0
198
1721
1.16
1.23
8.9
7.2
25.23
24.54
mmol/l
1.47
192
1641
24
155
1.55
1.23
1.0
1.1
—
—
—
0
0
19
116
1.64
1.21
1.1
1.1
136.43
200.26
iu/ml
0.98
19
116
27
180
1.50
1.20
1.1
1.1
274.95
294.63
mg/l
0.22
21
154
66
840
0.78
1.20
1.0
1.2
1.42
1.51
g/l
1.35
66
840
13
71
1.83
1.19
1.0
1.3
43.97
23.07
ug/l
—
7
33
15
86
1.75
1.19
1.5
1.6
0.27
2.88
%
2.29
15
74
43
315
1.37
1.18
1.6
1.2
—
—
—
0
0
39
533
0.73
1.18
1.5
1.6
949.28
978.48
mu/l
0.07
27
430
47
350
1.35
1.17
1.3
1.2
—
—
—
0
0
8
39
2.05
1.15
2.3
1.4
—
—
—
0
0
89
725
1.23
1.13
1.1
1.2
—
—
—
0
0
20
129
1.55
1.05
1.1
1.1
—
—
—
0
0
9
46
1.96
1.03
1.3
1.1
—
—
—
0
0
5
22
2.27
1.03
1.0
1.0
—
—
—
0
0
20
130
1.54
1.02
2.5
2.0
38.17
161.76
ug/min
—
6
34
94
782
1.21
1.01
2.7
2.3
—
—
—
0
0
18
115
1.57
0.99
1.9
2.5
77.38
51.20
umol/l
1.40
13
99
48
371
1.30
0.97
1.0
1.1
1.19
1.59
u/ml
0.17
28
186
10
54
1.85
0.96
3.4
1.6
—
—
—
0
0
26
182
1.43
0.96
1.4
2.0
6.56
7.01
mmol/l
0.48
21
117
33
242
1.37
0.94
1.3
1.5
480.00
317.18
mu/l
0.55
24
189
29
208
1.40
0.94
1.4
1.2
102.31
108.29
pmol/l
0.29
29
208
7
37
1.89
0.94
1.3
1.5
—
—
—
0
0
48
611
0.78
0.93
4.1
4.2
—
—
—
0
0
73
598
1.23
0.93
2.7
3.7
172.69
738.88
u/ml
0.71
66
565
92
772
1.20
0.92
2.4
2.2
—
—
—
0
0
6
28
2.15
0.91
1.5
1.9
48.83
50.93
umol/l
—
6
28
11
63
1.75
0.90
1.0
1.1
—
—
—
0
0
42
325
1.30
0.86
1.2
1.1
11.06
2.16
eliau/ml
0.89
15
134
76
632
1.21
0.85
1.2
1.1
30.25
5.59
eliau/ml
—
6
68
16
239
0.67
0.84
1.5
1.5
1.05
1.28
mm
—
9
168
93
790
1.18
0.83
2.7
2.2
—
—
—
0
0
19
129
1.48
0.83
1.0
1.1
1376.79
1526.87
miu/ml
0.26
19
129
73
607
1.21
0.82
3.1
2.3
—
—
—
0
0
29
214
1.36
0.82
1.2
1.1
—
—
—
0
0
92
786
1.18
0.78
2.7
2.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
0.28
—
0
9
85
726
1.18
0.74
2.8
2.3
—
—
—
0
0
13
84
1.55
0.71
1.8
2.2
—
—
—
0
0
17
241
0.70
0.71
1.5
1.5
—
—
—
0
0
26
195
1.34
0.69
1.7
1.8
5.55
7.22
umol/l
0.41
16
129
18
250
0.72
0.68
1.5
1.5
—
—
—
0
0
191
1742
1.10
0.64
1.3
1.3
—
—
—
0
0
46
377
1.22
0.64
1.3
1.2
—
—
—
0
0
5
29
1.73
0.64
2.2
1.5
—
—
—
0
0
93
813
1.15
0.63
7.3
6.6
1.20
1.33
mmol/l
1.26
84
707
15
104
1.44
0.62
1.5
1.2
9.87
8.83
mm/h
0.18
15
104
22
165
1.34
0.60
1.8
2.0
94.22
120.28
ng/l
0.64
22
165
0
22
0.00
0.59
0.0
1.1
—
21.71
—
0
7
29
228
1.27
0.58
3.6
3.2
44.89
36.89
mg/l
0.16
23
175
20
149
1.34
0.57
1.1
1.2
158.70
137.80
nmol/l
0.64
20
149
12
81
1.48
0.57
2.2
1.8
—
—
—
0
0
13
90
1.45
0.55
1.7
2.1
1675.00
22959.56
e6/l
—
8
52
15
107
1.40
0.55
3.0
3.4
—
—
—
0
0
69
792
0.87
0.53
1.0
1.1
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
0.10
9.06
u/ml
—
6
31
79
694
1.14
0.53
1.6
1.6
17914.72
13916.97
e6/l
0.31
53
478
20
152
1.32
0.52
1.1
1.2
—
—
—
0
0
18
135
1.34
0.51
15.9
13.1
0.62
0.63
mmol/l
0.11
18
126
6
41
1.46
0.50
1.5
1.8
5.17
9.90
%
—
6
20
18
136
1.33
0.49
1.0
1.0
—
—
—
0
0
37
308
1.20
0.48
3.5
2.6
—
—
—
0
0
26
208
1.25
0.48
1.2
1.5
1.09
1.12
promille
0.03
17
162
84
748
1.13
0.47
1.1
1.1
—
—
—
0
0
7
47
1.49
0.47
1.0
1.0
—
—
—
0
0
7
48
1.46
0.46
1.0
1.0
27.77
50.33
iu/ml
—
7
48
37
312
1.19
0.43
1.0
1.1
1.97
4.71
u/ml
1.17
20
140
63
555
1.14
0.43
2.1
2.2
12257.55
4432.14
u/l
0.42
15
228
5
31
1.61
0.43
1.0
1.3
—
—
—
0
0
5
31
1.61
0.43
1.0
1.4
—
—
—
0
0
5
31
1.61
0.43
1.0
1.3
—
—
—
0
0
5
31
1.61
0.43
1.0
1.3
—
—
—
0
0
21
262
0.80
0.42
4.6
2.0
—
—
—
0
0
5
32
1.56
0.42
1.4
1.3
—
640.53
—
0
9
12
87
1.38
0.42
1.2
1.4
6.44
7.94
mmol/l
0.72
12
87
17
131
1.30
0.42
2.1
1.7
—
—
—
0
0
19
149
1.28
0.41
1.1
1.4
7.46
7.40
ph
1.24
13
102
40
342
1.17
0.41
1.0
1.1
1.67
2.28
u/ml
0.30
24
174
5
34
1.47
0.40
1.0
1.3
—
—
mmol/l
—
0
0
244
2309
1.06
0.38
2.5
2.4
8.14
7.58
ug/l
0.14
204
2067
5
36
1.39
0.38
1.2
1.1
0.34
0.02
u/ml
—
5
36
39
336
1.16
0.37
1.9
1.7
—
—
—
0
0
22
179
1.23
0.37
1.0
1.1
10.09
4.30
nmol/l
—
5
41
10
133
0.75
0.33
1.1
1.1
—
—
—
0
0
6
47
1.28
0.32
2.0
1.9
97.45
42.61
pmol/l
—
6
40
7
53
1.32
0.30
1.7
2.3
—
—
—
0
0
11
84
1.31
0.30
1.5
1.5
21.37
27.00
%
0.28
11
78
7
55
1.27
0.30
1.4
1.9
—
92.20
—
0
5
7
55
1.27
0.30
17.3
7.9
8.00
5.38
kpa
—
7
55
43
384
1.12
0.27
1.0
1.1
0.09
1.56
u/ml
2.50
18
166
34
382
0.89
0.24
7.6
5.9
376.97
356.47
umol/l
0.39
29
340
307
3173
0.96
0.24
5.7
5.1
30.30
32.45
%
3.08
222
2080
44
398
1.11
0.24
1.1
1.1
2.62
4.77
u/ml
0.78
24
208
5
39
1.28
0.23
1.0
1.4
67.80
68.95
ug/l
—
5
39
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
557.43
—
0
11
0
10
0.00
0.21
0.0
1.9
—
313.10
—
0
10
0
10
0.00
0.21
0.0
1.2
—
5.24
—
0
5
0
12
0.00
0.21
0.0
1.1
—
0.12
—
0
5
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
24
211
1.14
0.20
1.5
2.1
3.75
1.54
u/field
0.72
16
112
0
14
0.00
0.20
0.0
1.1
—
0.11
—
0
6
0
14
0.00
0.20
0.0
1.2
—
0.16
—
0
14
32
289
1.11
0.19
1.0
1.0
0.45
0.25
u/ml
0.20
14
103
128
1224
1.05
0.18
2.3
2.0
—
—
—
0
0
7
60
1.17
0.17
1.0
1.2
—
—
—
0
0
11
92
1.20
0.16
2.0
2.0
0.27
0.07
estimate
0.33
11
92
10
84
1.19
0.14
1.0
1.0
—
—
—
0
0
13
149
0.87
0.13
1.1
1.1
—
—
—
0
0
228
2224
1.03
0.13
1.5
1.4
—
—
—
0
0
105
1089
0.96
0.12
1.8
1.7
—
—
—
0
0
117
1136
1.03
0.10
6.3
5.7
0.86
0.88
%
0.20
112
1063
76
789
0.96
0.10
19.0
10.2
—
—
—
0
0
61
586
1.04
0.09
1.4
1.4
—
—
—
0
0
11
98
1.12
0.07
2.3
3.5
—
—
—
0
0
9
86
1.05
0.07
1.0
1.0
—
—
—
0
0
9
86
1.05
0.07
1.0
1.0
—
—
—
0
0
9
86
1.05
0.07
1.0
1.0
—
—
—
0
0
19
177
1.07
0.06
1.7
1.6
86.95
85.44
umol/l
0.04
19
177
31
323
0.96
0.05
2.5
2.3
23.73
21.40
mg/l
0.11
11
115
13
120
1.08
0.04
1.0
1.0
35.89
0.33
u/ml
—
5
29
52
534
0.97
0.04
3.4
3.6
17.39
27.34
mg/l
3.23
39
368
55
536
1.03
0.04
1.4
1.6
—
—
—
0
0
58
594
0.98
0.04
1.2
1.2
—
—
—
0
0
22
210
1.05
0.03
1.0
1.0
248.94
298.31
ng/l
0.38
17
137
78
767
1.02
0.03
6.4
4.2
3.93
3.90
mmol/l
0.20
78
760
19
181
1.05
0.03
1.0
1.1
—
—
—
0
0
10
92
1.09
0.03
1.4
1.9
—
—
—
0
0
22
211
1.04
0.03
1.0
1.0
803.69
720.97
ng/l
0.33
16
134
18
173
1.04
0.01
1.4
2.1
8.56
8.16
mmol/l
0.16
18
173
25
248
1.01
0.00
1.2
1.3
92175.24
107754.59
e6/l
0.08
17
168
27
268
1.01
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
375.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
3.39
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
107.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
7
70
1.00
-0.00
1.0
1.0
6.03
8.87
u/ml
—
7
45
129
1290
1.00
-0.00
3.4
3.4
1.02
1.02
ratio
0.17
108
1177
6
67
0.90
-0.00
3.0
2.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_OTHERBLOOD and mortality.

Females

Parameter HR [95% CI] p-value
D3_OTHERBLOOD 1.985 [1.78, 2.22] < 0.001
Birth year 0.996 [0.99, 1.0] 0.293

During the follow-up period (1.1.1998 — 31.12.2019), 1658 out of 6103 females with D3_OTHERBLOOD died.

Males

Parameter HR [95% CI] p-value
D3_OTHERBLOOD 1.825 [1.62, 2.05] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 1754 out of 6045 males with D3_OTHERBLOOD died.

Mortality risk

Mortality risk for people of age

years, who have D3_OTHERBLOOD.

N-year risk Females Males
1 0.216% 0.396%
5 1.289% 2.196%
10 3.139% 5.364%
15 5.656% 9.533%
20 10.057% 16.307%

Relationships between endpoints

Index endpoint: D3_OTHERBLOOD – Other diseases of blood and blood-forming organs

GWS hits: 6

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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