polycythemia: Abnormally high mass or concentration of red blood cells in the blood, either due to an increase in erythropoiesis or a decrease in plasma volume.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1029 |
4. Check minimum number of eventsNone |
1029 |
5. Include endpointsNone |
1029 |
6. Filter based on genotype QC (FinnGen only) |
921 |
Control definitions (FinnGen only)
- Control exclude
- D3_BLOODOTHER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D75
- Name in latin
- Polycythaemia secundaria
Similar endpoints
↥List of similar endpoints to
Secondary polycythaemia
based on the number of shared cases.
Similar with more cases:
- Other diseases of blood and blood-forming organs
- Other diseases of blood and blood-forming organs, wide
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5793 | 1925 | 3795 |
| Only index persons | 4662 | 1564 | 3098 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.06 | 0.11 |
| Only index persons | 0.10 | 0.06 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 58.75 | 60.79 | 57.65 |
| Only index persons | 57.47 | 60.07 | 56.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 921 | 326 | 595 |
| Unadjusted period prevalence (%) | 0.22 | 0.12 | 0.27 |
| Median age at first event (years) | 58.55 | 57.35 | 59.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 950
- Matched controls
- 9500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D75.1
ICD-10 Finland
Secondary polycythaemia
16384.0
307.7
886
5
D45
ICD-10 Finland
Polycythaemia vera
75.8
242.4
131
20
XW000
NOMESCO Finland
Bone marrow biopsy
11.3
121.9
136
138
SPAT1074
SPAT
Venesection
38.1
86.9
54
15
TPH00
NOMESCO Finland
Phlebotomy
80.1
53.7
60
8
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
4.6
53.5
143
356
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
524.8
50.9
50
*
D75.0
ICD-10 Finland
Familial erythrocytosis
513.7
49.9
49
*
28900
ICD-8 Finland
Other disease of blood and blood-forming organs, Polycythaemia, secondary
+∞
48.3
46
*
G47.3
ICD-10 Finland
Sleep apnoea
2.8
47.7
363
1732
T90
ICPC
Diabetes non-insulin dependent
2.8
46.2
348
1647
103
Kela drug reimbursment
Diabetes, insulin-treated
2.7
45.4
372
1834
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.7
44.8
340
1610
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.7
44.8
347
1661
A10BA02
ATC
metformin; oral
2.6
43.1
383
1955
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
17.3
42.0
35
21
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
9.3
39.2
48
54
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
35.1
191
749
L01XX05
ATC
hydroxycarbamide; oral
12.6
34.3
34
28
SPAT1262
SPAT
Handing over of treatment supplies
2.7
33.1
227
1002
E29.1
ICD-10 Finland
Testicular hypofunction
7.2
32.9
50
73
R71
ICD-10 Finland
Abnormality of red blood cells
50.7
32.7
39
8
C03CA01
ATC
furosemide; systemic
2.3
30.9
343
1878
J96.1
ICD-10 Finland
Chronic respiratory failure
5.7
27.2
52
96
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
26.4
158
646
C01AA05
ATC
digoxin; systemic
3.3
25.9
107
355
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
25.7
520
3520
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.4
25.6
212
1011
A10BH01
ATC
sitagliptin; oral
2.8
24.5
137
539
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
24.1
177
797
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.2
24.1
100
332
R5140
NOMESCO Finland
Monitoring the use of the aid
2.5
23.5
167
740
A10BJ06
ATC
semaglutide; parenteral
3.3
23.2
92
297
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.1
22.4
284
1604
C07AB07
ATC
bisoprolol; oral
1.9
22.1
508
3525
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
21.8
635
4768
D75.2
ICD-10 Finland
Essential thrombocytosis
117.7
21.7
23
*
205
Kela drug reimbursment
Chronic hypertension
2.0
21.2
289
1671
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
20.7
118
468
E66.8
ICD-10 Finland
Other obesity
3.5
20.6
73
219
B99
ICPC
Blood/lymph/spleen disease other
42.7
20.5
25
6
C03DA01
ATC
spironolactone; oral
2.4
20.4
154
699
207
Kela drug reimbursment
Chronic arrhythmias
2.3
20.3
185
912
C07AB02
ATC
metoprolol; systemic
2.2
20.0
214
1126
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.1
19.9
88
303
A10AE04
ATC
insulin glargine; parenteral
2.5
19.4
131
564
M04AA01
ATC
allopurinol; systemic
2.3
19.2
159
751
R03BB04
ATC
tiotropium bromide; inhalant
2.5
19.0
130
563
9950/3-C42.1
ICD-O-3
Polycythemia vera of bone marrow
56.2
19.0
22
*
A10BK03
ATC
empagliflozin; oral
2.4
18.4
141
644
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.0
18.1
233
1309
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
18.1
366
2393
C08CA01
ATC
amlodipine; oral
1.8
17.9
402
2713
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
5.1
17.5
37
75
E66.00
ICD-10 Finland
Metabolic syndrome
3.0
17.3
81
288
R06.0
ICD-10 Finland
Dyspnoea
1.9
17.2
288
1765
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
15.1
17.2
28
19
A10BK01
ATC
dapagliflozin; oral
2.6
16.8
107
447
E66.01
ICD-10 Finland
Obesity due to excess calories
2.5
16.4
108
458
TPH00, ,
SPAT
40.8
16.4
20
5
XG466
NOMESCO Finland
Sleep oxymetry
3.6
16.0
53
152
N06AX12
ATC
bupropion; oral
2.8
16.0
86
330
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
15.7
155
784
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.5
15.7
54
159
D58.2
ICD-10 Finland
Other haemoglobinopathies
+∞
15.7
15
*
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
6.6
15.4
25
39
121
Kela drug reimbursment
Severe hypofunction of sexual glands
5.3
15.4
31
60
B01AA03
ATC
warfarin; systemic
2.0
15.3
197
1100
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.0
14.9
67
233
R03AC02
ATC
salbutamol; inhalant
1.7
14.4
512
3862
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.3
14.4
124
593
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
14.3
72
267
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
14.2
253
1567
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
14.0
175
964
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.8
13.6
70
262
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.3
13.3
50
156
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.9
428
3139
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.8
12.9
65
241
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
12.8
194
1139
I50.0
ICD-10 Finland
Congestive heart failure
2.5
12.8
85
362
OAB50, ,
SPAT
2.3
12.7
98
447
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
6.1
12.6
22
37
C09AA02
ATC
enalapril; systemic
1.9
12.6
196
1159
2890X
ICD-9 Finland
Other diseases of blood and blood-forming organs, Polycythaemia, secondary[ERYTHROCYTOSIS SECUNDARIA, NUD]
+∞
12.5
12
*
E66.9
ICD-10 Finland
Obesity, unspecified
3.4
12.5
44
132
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.4
12.4
86
373
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.3
12.3
46
143
WX723
NOMESCO Finland
CPAP therapy
2.8
12.3
65
247
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.0
12.2
56
197
A10BJ02
ATC
liraglutide; parenteral
3.4
12.2
43
129
C02AC05
ATC
moxonidine; oral
2.8
11.9
62
234
H02AB06
ATC
prednisolone; systemic
1.6
11.8
446
3354
WX780
NOMESCO Finland
Remote monitoring CPAP
2.7
11.6
65
255
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
11.6
189
1133
N06AX11
ATC
mirtazapine; oral
1.7
11.5
316
2191
Y28
ICPC
Limited function/disability (Y)
13.8
11.5
19
14
SPAT1377
SPAT
Polysomnography
3.3
11.3
43
135
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
11.3
127
671
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.7
11.2
60
230
A10AB05
ATC
insulin aspart; parenteral
2.3
11.1
88
405
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
43.8
10.9
13
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
10.9
177
1059
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
10.7
177
1062
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.4
212
1354
ZXE00
NOMESCO Finland
One hour or less
1.6
10.1
341
2471
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.2
10.1
39
124
A02BC02
ATC
pantoprazole; systemic
1.6
10.1
633
5285
SPAT1260
SPAT
Consultation of another employee
1.8
10.0
158
935
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.9
9.8
132
742
M10.9
ICD-10 Finland
Gout, unspecified
2.2
9.8
82
387
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
9.8
312
2229
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
9.8
122
669
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
9.2
9.5
19
21
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.2
9.5
18
18
SPAT1263
SPAT
Sampling
1.6
9.5
360
2671
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
9.5
146
856
TFP20
NOMESCO Finland
Cardiodefibrillation
2.2
9.5
83
399
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
9.4
271
1885
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.7
9.4
50
191
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.8
9.4
28
75
J45.8
ICD-10 Finland
Mixed asthma
3.4
9.4
33
99
C09AA05
ATC
ramipril; oral
1.6
9.3
249
1703
L28
ICPC
Limited function/disability (L)
1.8
9.2
167
1029
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.5
9.1
55
224
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
9.1
255
1761
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
37.1
9.0
11
*
N06AB10
ATC
escitalopram; oral
1.7
8.9
175
1103
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
8.8
165
1024
C09CA01
ATC
losartan; oral
1.6
8.8
248
1714
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
8.8
136
799
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.8
227
1536
N07BA03
ATC
varenicline; oral
2.5
8.7
56
235
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.1
8.7
36
120
Z72.0
ICD-10 Finland
Tobacco use
3.1
8.7
36
120
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
8.7
87
441
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.1
8.6
79
386
C10AA01
ATC
simvastatin; oral
1.5
8.6
382
2918
I50.1
ICD-10 Finland
Left ventricular failure
2.5
8.5
54
225
D70.82
ICD-10 Finland
Drug-induced neutropenia
90.8
8.4
9
*
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
12.9
8.4
14
11
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
8.3
8
*
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.2
8.3
32
102
SPAT1281
SPAT
Other administrative function
2.1
8.1
74
362
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
8.0
128
758
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.5
8.0
27
79
C08CA02
ATC
felodipine; oral
2.0
7.9
89
470
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.9
110
624
A10BB12
ATC
glimepiride; oral
2.2
7.9
69
332
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
7.7
352
2688
M54.5
ICD-10 Finland
Low back pain
1.5
7.7
324
2434
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
7.7
219
1510
N06AB06
ATC
sertraline; oral
1.9
7.7
100
555
I50
ICD-10 Finland
Heart failure
3.0
7.6
33
113
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.9
7.6
22
58
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.8
7.5
37
136
R03BA05
ATC
fluticasone; inhalant
1.7
7.4
155
990
212
Kela drug reimbursment
Gout
3.8
7.4
22
59
M10
ICD-10 Finland
Gout
2.4
7.4
51
222
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.0
7.3
32
110
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
9.5
7.3
14
15
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.3
7.3
27
84
A10BH02
ATC
vildagliptin; oral
3.4
7.3
25
74
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.9
7.3
95
528
J01AA02
ATC
doxycycline; systemic
1.5
7.2
702
6184
A10BJ01
ATC
exenatide; parenteral
4.5
7.2
17
38
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
7.2
109
635
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
3.3
7.1
26
80
H02AB09
ATC
hydrocortisone; systemic
3.3
7.1
26
80
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
7.1
123
745
T82
ICPC
Obesity
2.5
7.1
42
170
WZC00, ,
SPAT
1.7
7.1
131
809
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
7.1
185
1249
B04
ICPC
Blood symptom/complaint
10.1
7.0
13
13
SPAT1254
SPAT
Administration of medicine
1.7
7.0
124
755
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
7.0
125
763
A12BA01
ATC
potassium chloride; oral
2.6
7.0
39
153
K99
ICPC
Cardiovascular disease other
3.1
7.0
29
97
GX2D5
NOMESCO Finland
Sleep oximetry
7.6
6.9
15
20
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.9
342
2644
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
6.8
172
1150
C03AA03
ATC
hydrochlorothiazide; oral
2.0
6.8
77
408
R95
ICPC
Chron obstructive pulmonary disease
2.7
6.8
35
132
J01DB01
ATC
cefalexin; oral
1.5
6.8
746
6687
OAB75, ,
SPAT
3.1
6.8
27
88
D75.8
ICD-10 Finland
Other specified diseases of blood and blood-forming organs
40.3
6.8
8
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
6.8
634
5503
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.3
6.7
24
73
H03AA01
ATC
levothyroxine sodium; systemic
1.6
6.6
169
1133
N05BA04
ATC
oxazepam; oral
1.5
6.6
222
1584
G04CA02
ATC
tamsulosin; oral
1.5
6.6
249
1820
SPAT1310
SPAT
Counselling related to known health issue
1.5
6.6
259
1909
N05CF02
ATC
zolpidem; oral
1.6
6.6
149
970
C09DA01
ATC
losartan and diuretics; oral
1.8
6.5
101
594
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.3
6.4
45
197
ZXD05
NOMESCO Finland
Urgent procedure
1.5
6.4
255
1881
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
6.4
160
1066
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
6.4
97
565
Z02.7
ICD-10 Finland
Issue of medical certificate
2.0
6.3
70
368
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
6.3
61
305
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
6.3
234
1703
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
6.3
88
501
A10AE05
ATC
insulin detemir; parenteral
2.2
6.3
53
252
D70.89
ICD-10 Finland
Neutropenic splenomegaly
26.9
6.2
8
*
S01
ICPC
Pain/tenderness of skin
2.3
6.2
44
194
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.5
6.2
38
157
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
6.2
83
466
R52.9
ICD-10 Finland
Pain, unspecified
1.8
6.2
92
534
160
Kela drug reimbursment
exenatide
3.0
6.1
26
88
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
2.9
6.1
28
99
B01AB05
ATC
enoxaparin; parenteral
1.5
6.1
264
1979
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.1
454
3753
N05AH04
ATC
quetiapine; oral
1.6
6.1
158
1064
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
505
139
76.43
307.65
1.4
1.3
14.69
45.38
u/l
1.31
450
120
414
94
77.29
307.65
1.1
1.0
—
—
—
0
0
110
106
11.61
101.74
1.1
1.9
—
—
—
0
0
309
927
4.46
94.16
3.2
4.3
234.74
250.42
u/l
0.74
287
878
356
1208
4.11
91.31
2.5
2.8
25.38
23.27
%
1.98
331
1134
364
1292
3.95
86.90
2.5
2.7
2.55
2.29
g/l
15.44
338
1202
372
1398
3.73
80.64
2.7
2.7
15.57
13.29
umol/l
6.04
347
1307
733
4603
3.59
62.92
10.9
9.8
4.63
4.18
e9/l
5.43
659
4003
204
722
3.32
45.58
2.5
2.7
93.00
69.47
e9/l
11.72
156
532
85
162
5.66
43.19
5.8
4.7
3.32
2.59
mmol/l
0.86
60
109
490
2859
2.47
40.77
5.4
4.3
11.72
9.39
mg/mmol
0.52
333
1845
409
2237
2.45
38.73
3.3
2.8
372.25
355.04
umol/l
2.72
365
1984
566
3584
2.43
38.43
16.9
11.5
0.00
0.00
e9/l
0.56
486
2954
494
2974
2.38
37.23
4.2
3.5
7.98
8.09
mmol/l
0.20
407
2519
636
4347
2.40
34.76
7.8
6.9
13.92
12.00
umol/l
3.52
620
4165
555
3600
2.30
33.99
3.7
3.0
148.58
148.91
ug/l
0.01
521
3350
797
6201
2.77
30.38
10.9
8.5
83.07
79.05
u/l
1.30
768
5893
55
107
5.39
27.20
1.8
2.2
33.40
33.01
pg
0.22
55
107
86
245
3.76
26.30
1.8
1.4
6.22
7.79
u/l
0.76
65
197
536
3656
2.07
26.09
8.8
7.3
1.21
1.21
mmol/l
0.74
506
3378
71
178
4.23
25.89
3.2
2.6
19.56
16.53
%
7.48
71
173
150
626
2.66
23.91
4.4
4.1
1.22
1.22
mmol/l
0.28
133
541
573
4079
2.02
23.89
9.2
7.9
1.21
1.21
mmol/l
0.31
469
3529
400
2534
2.00
23.05
4.2
3.2
1384.70
1330.58
ng/l
0.12
334
2152
556
3948
1.98
22.97
22.2
14.6
1.34
1.25
inr
2.89
482
3285
520
3624
1.96
22.52
5.9
5.4
35.60
35.75
g/l
0.25
489
3401
644
4885
1.99
21.11
7.9
5.6
7.23
6.77
mmol/l
5.49
633
4680
219
1141
2.19
21.07
6.6
6.8
1.03
1.03
mmol/l
0.05
207
1058
203
1048
2.19
19.87
5.2
2.4
14.11
13.70
nmol/l
0.26
186
960
81
266
3.24
19.84
2.7
3.1
1.50
1.59
mg/l
0.44
68
243
124
521
2.59
19.33
3.9
3.5
2.94
1.80
mmol/l
2.22
91
382
188
963
2.19
18.67
2.7
2.8
9.12
8.49
umol/l
0.19
171
863
417
2840
1.83
18.04
4.1
3.6
34.41
35.02
u/l
0.11
402
2677
403
2722
1.83
17.87
4.5
3.4
101.44
76.11
e6/l
0.21
324
2095
304
1884
1.90
17.66
3.8
2.8
4.20
4.27
e6/l
0.05
275
1719
357
2329
1.85
17.66
4.3
3.3
0.54
0.46
e6/l
0.15
282
1714
465
3289
1.81
17.63
5.2
3.8
23.55
42.34
ng/l
4.85
371
2394
64
204
3.29
16.44
2.3
2.3
161.35
131.69
g/l
11.07
57
162
190
1025
2.07
16.32
9.5
9.8
1.88
0.90
mmol/l
1.89
158
846
725
5959
1.91
15.92
5.0
4.3
7.43
11.74
mm/h
17.70
686
5567
719
5898
1.90
15.83
5.2
3.9
15.21
14.81
pmol/l
3.79
660
5403
165
862
2.11
15.37
4.9
3.4
—
—
—
0
0
100
423
2.52
15.29
2.9
2.0
32.00
37.67
nmol/l
2.48
100
409
428
3053
1.73
14.97
5.4
4.1
110.23
90.70
e6/l
0.25
337
2193
235
1431
1.85
13.93
4.4
3.5
0.82
0.82
mmol/l
0.02
224
1357
284
1835
1.78
13.83
2.0
1.7
1.03
1.24
mg/l
0.77
219
1437
29
59
5.04
13.64
1.6
1.9
18.54
19.66
nmol/l
0.25
29
53
231
1409
1.84
13.58
2.2
1.9
—
—
—
0
0
306
2055
1.72
12.84
4.8
4.3
83.29
88.97
%
3.23
297
2021
63
231
2.85
12.74
1.9
1.7
233.24
266.41
mu/l
0.62
58
219
339
2345
1.69
12.74
4.7
3.9
0.01
0.01
estimate
0.04
150
796
145
781
2.01
12.29
2.9
2.0
354.40
373.70
nmol/l
0.64
138
735
545
4283
1.64
12.24
4.6
3.8
0.02
0.02
estimate
0.05
145
806
371
2653
1.65
12.13
3.4
2.8
50.50
61.38
u/l
3.86
344
2485
542
4265
1.63
12.01
4.6
3.8
8.02
5.95
estimate
0.09
168
888
536
4214
1.62
11.86
4.6
3.8
0.00
0.00
estimate
-0.00
166
873
38
108
3.62
11.67
1.9
1.6
—
—
—
0
0
90
413
2.30
11.46
3.5
3.7
4.66
4.56
pmol/l
0.47
80
374
329
2309
1.65
11.43
4.2
3.2
0.00
0.01
estimate
0.99
137
675
45
146
3.19
11.26
1.6
1.8
—
—
—
0
0
32
83
3.95
11.18
1.8
1.3
26.98
28.35
ng/l
0.09
32
83
146
814
1.94
11.16
8.7
8.4
9.76
9.97
mmol/l
0.16
141
779
125
662
2.02
11.07
2.6
2.9
64.96
66.76
g/l
1.60
112
614
56
212
2.74
10.69
3.4
3.8
9.57
1.84
index
0.88
30
125
61
243
2.61
10.54
2.3
3.9
1.78
2.54
ratio
0.72
30
141
121
646
2.00
10.46
2.3
2.5
9.70
10.92
g/l
2.91
108
599
46
163
2.91
9.93
3.6
3.3
0.78
0.88
nmol/l
0.56
39
136
64
270
2.47
9.84
2.7
4.1
48.38
46.93
mg/l
0.03
49
234
64
271
2.46
9.76
2.7
4.1
48.23
74.60
mg/l
0.59
48
233
805
7170
1.80
9.70
6.6
4.9
1.90
1.92
mu/l
0.18
739
6603
103
534
2.04
9.64
10.8
12.6
24.51
24.35
mmol/l
0.17
103
527
32
95
3.45
9.24
1.7
1.5
0.20
0.27
nmol/l
0.68
24
71
419
3233
1.53
9.17
4.4
3.7
0.20
0.02
estimate
0.53
147
725
846
7693
1.91
8.96
25.1
15.5
78.13
81.36
ml/min/173m2
4.48
812
7147
448
3522
1.51
8.90
2.8
2.4
72.51
75.91
nmol/l
1.92
409
3167
53
215
2.55
8.86
1.7
1.6
—
—
—
0
0
288
2063
1.57
8.74
2.8
2.2
5.00
2.93
mg/l
7.41
248
1777
746
6565
1.63
8.71
30.2
19.9
14.42
13.62
%
20.29
741
6492
106
584
1.92
8.34
4.3
4.3
97.05
95.56
ng/l
0.06
85
509
349
2635
1.51
8.23
2.4
2.2
250.63
251.08
u/l
0.00
320
2505
857
7871
1.91
8.13
23.8
16.1
21.32
25.19
mg/l
3.35
776
6482
599
5056
1.50
8.09
6.1
4.5
177.43
958.59
e6/l
0.86
14
76
95
510
1.96
8.06
5.1
3.9
23.92
24.24
mmol/l
0.36
95
504
142
868
1.75
7.98
4.8
3.8
1.54
1.87
mmol/l
0.46
128
738
239
1677
1.57
7.81
2.0
1.7
70968168.07
23016874.43
pmol/l
0.45
186
1399
29
92
3.22
7.58
1.3
1.3
0.21
0.18
nmol/l
0.55
21
71
26
77
3.44
7.56
3.4
4.2
18.09
12.11
index
1.06
11
54
833
7622
1.75
7.49
9.9
6.5
42.43
39.53
mmol/mol
10.88
770
7181
355
2742
1.47
7.26
3.7
3.6
2.37
2.35
mmol/l
1.63
321
2498
163
1066
1.64
7.09
2.1
1.8
—
—
—
0
0
156
1011
1.65
7.03
2.1
1.9
—
—
—
0
0
649
5644
1.47
6.97
4.3
3.5
62.34
52.80
u/l
1.67
609
5341
868
8081
1.86
6.78
30.0
19.4
139.67
139.73
mmol/l
0.35
862
7944
19
49
3.94
6.73
1.4
1.5
—
—
—
0
0
50
225
2.29
6.72
1.7
1.6
—
—
—
0
0
39
159
2.52
6.51
1.6
1.5
—
—
—
0
0
38
153
2.55
6.50
1.6
1.4
160.50
162.82
au/ml
0.04
12
48
868
8100
1.83
6.46
30.5
19.6
4.00
3.99
mmol/l
0.02
862
7953
441
3616
1.41
6.25
2.1
2.1
89.95
94.99
pmol/l
1.53
245
1956
167
1133
1.58
6.20
2.0
2.0
1.52
1.54
%
0.11
146
992
18
48
3.80
6.11
1.4
1.5
—
—
—
0
0
30
111
2.76
6.06
2.0
1.5
—
—
—
0
0
26
89
2.98
6.03
1.8
1.3
161.72
165.46
pmol/l
0.04
26
89
424
3469
1.40
6.01
2.3
2.0
1.74
1.41
mmol/l
6.82
333
2931
99
597
1.73
5.82
12.7
12.3
91.18
94.07
%
3.37
99
592
820
7581
1.60
5.76
5.5
4.4
1.63
1.35
mmol/l
14.18
749
7027
21
66
3.23
5.62
1.9
1.5
—
—
—
0
0
829
7695
1.61
5.59
7.0
5.2
6.51
6.02
mmol/l
12.30
759
7094
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
54
274
2.03
5.42
3.9
2.6
0.38
0.33
iu/ml
0.65
35
141
21
68
3.14
5.36
2.5
2.3
573.69
640.20
ml
0.51
13
40
100
629
1.66
5.04
3.5
3.1
299.16
196.43
ng/l
1.50
87
570
18
56
3.26
4.91
1.4
1.5
—
—
—
0
0
51
265
1.98
4.82
1.8
1.4
13.22
24.69
iu/l
3.43
46
218
9
10
9.07
4.79
1.0
1.0
—
—
—
0
0
32
139
2.35
4.73
1.3
1.5
—
—
—
0
0
205
1532
1.43
4.69
1.4
1.4
2.88
2.59
g/l
0.71
145
960
40
192
2.13
4.67
1.6
1.5
—
—
—
0
0
83
510
1.69
4.58
1.3
1.3
161.93
259.44
u/ml
0.93
78
478
7
5
14.09
4.58
1.0
6.0
—
—
—
0
0
48
249
1.98
4.57
1.7
1.7
—
—
—
0
0
38
181
2.15
4.53
1.7
2.0
2.67
4.37
iu/l
1.11
14
72
44
223
2.02
4.47
2.4
2.4
63.99
143.22
ug/min
0.97
23
134
39
191
2.09
4.35
1.6
1.5
—
—
—
0
0
854
8072
1.57
4.30
7.5
5.9
2.55
2.70
mmol/l
5.51
790
7541
28
120
2.37
4.28
1.2
1.1
—
—
—
0
0
99
653
1.58
4.14
1.6
1.4
—
—
—
0
0
840
7925
1.52
4.11
6.5
5.1
1.20
1.40
mmol/l
47.81
776
7390
47
252
1.91
4.09
2.7
2.9
0.02
0.02
g/l
0.05
42
230
843
7964
1.52
4.04
6.6
5.2
4.29
4.58
mmol/l
14.90
784
7470
32
150
2.17
4.00
1.2
1.1
252.20
79.06
iu/ml
—
10
28
46
247
1.91
4.00
2.6
2.9
0.00
0.00
g/l
-0.00
41
217
51
284
1.84
3.97
3.0
2.9
0.67
1.18
g/l
0.72
43
254
177
1327
1.41
3.94
2.8
2.2
31.88
29.63
s
2.89
171
1294
91
598
1.58
3.88
13.5
12.1
1.68
1.33
%
1.97
91
593
34
166
2.09
3.85
1.3
1.2
312.38
285.08
u/ml
0.20
24
95
46
252
1.87
3.78
1.7
1.4
286.33
274.97
ug/g
0.12
27
160
82
533
1.59
3.67
1.9
1.6
—
—
—
0
0
61
368
1.70
3.64
1.8
1.9
0.58
2.25
ug/l
1.36
54
326
27
123
2.23
3.63
1.7
1.2
1.71
4.10
u/ml
—
7
49
36
184
1.99
3.62
1.3
1.3
38.31
1181.48
e6/l
0.90
29
141
62
379
1.68
3.54
1.7
1.9
1.34
1.54
g/l
1.09
57
333
35
180
1.98
3.47
1.3
1.2
10.58
14.89
e6/l
0.20
26
131
32
160
2.03
3.43
4.2
4.4
9.55
9.87
pmol/l
0.09
32
160
438
3817
1.27
3.35
5.3
5.1
1.81
2.26
ug/l
1.75
398
3464
874
8373
1.55
3.34
17.5
12.2
34.19
28.29
u/l
5.15
854
8161
13
43
3.05
3.26
1.2
1.1
—
—
—
0
0
41
229
1.83
3.21
2.7
2.9
0.00
0.00
g/l
-0.00
41
216
77
513
1.55
3.13
12.9
13.3
17.72
16.06
%
4.36
77
494
32
166
1.96
3.12
1.3
1.5
—
—
—
0
0
50
299
1.71
3.12
5.4
4.2
1.36
1.40
mmol/l
0.12
50
291
174
1353
1.35
3.08
4.2
3.1
2.87
1.63
e6/l
0.56
93
678
187
1472
1.34
3.05
4.2
3.0
0.99
0.92
e6/l
0.08
108
798
43
249
1.76
3.01
1.2
1.3
—
—
—
0
0
10
26
3.88
2.98
1.0
1.1
—
—
—
0
0
109
794
1.42
2.86
2.6
2.5
38.50
40.43
u/l
0.08
96
674
19
83
2.32
2.85
1.3
1.3
—
—
—
0
0
21
96
2.21
2.85
1.0
1.1
—
—
—
0
0
201
1617
1.31
2.81
5.2
4.0
1535.73
530.98
ng/l
0.36
157
1289
170
1336
1.33
2.80
1.9
1.7
1135.71
1179.05
nmol/l
0.25
129
1017
424
3743
1.24
2.72
3.2
2.8
—
—
estimate
—
0
0
26
133
1.98
2.67
1.2
1.1
0.57
1.72
u/ml
0.85
17
77
195
1573
1.30
2.66
3.0
3.1
2.48
2.44
mmol/l
3.69
168
1416
30
163
1.87
2.60
3.6
3.8
11.77
27.74
mg/l
4.66
22
110
5
7
7.17
2.55
1.6
1.0
—
—
—
0
0
51
326
1.60
2.51
4.2
4.0
25.09
24.87
mmol/l
0.24
45
303
12
45
2.69
2.45
1.0
1.1
0.92
1.11
u/l
—
5
22
209
1720
1.28
2.44
1.3
1.3
0.84
1.82
u/ml
1.84
75
491
11
38
2.92
2.42
2.5
3.7
—
—
—
0
0
82
587
1.43
2.39
1.5
1.6
—
—
—
0
0
34
199
1.73
2.34
1.1
1.8
1.04
0.89
nmol/l
0.54
29
170
19
91
2.11
2.34
2.7
3.2
4.69
4.94
nmol/l
0.04
19
91
12
47
2.57
2.27
1.6
1.2
0.51
0.51
ratio
—
5
28
32
187
1.74
2.23
1.4
1.2
—
—
—
0
0
16
73
2.21
2.22
1.4
1.5
553.09
295.73
mu/l
0.42
11
56
66
461
1.46
2.21
1.3
1.2
147.25
133.68
u/ml
0.07
20
178
10
37
2.72
2.07
6.7
7.3
3.28
25.48
ug/l
—
5
27
7
20
3.52
2.06
1.0
1.7
—
—
—
0
0
12
51
2.37
1.95
1.3
1.5
5.71
7.69
u/l
—
7
42
47
315
1.52
1.94
2.2
1.9
—
—
—
0
0
6
16
3.77
1.93
3.7
1.5
1.17
1.23
mmol/l
—
6
16
153
1248
1.27
1.92
1.5
1.5
—
—
—
0
0
17
85
2.02
1.91
1.0
1.1
—
—
—
0
0
22
121
1.84
1.89
1.8
1.2
4.00
5.61
u/ml
0.29
12
57
23
129
1.80
1.87
1.2
1.4
—
—
—
0
0
13
59
2.22
1.84
1.1
1.2
43.64
45.10
mg/l
—
7
49
343
3054
1.19
1.84
4.3
4.2
22.70
21.25
%
1.02
160
1365
33
208
1.61
1.79
1.2
1.3
116.43
217.59
miu/ml
1.18
12
85
43
290
1.51
1.75
2.1
1.8
—
—
—
0
0
12
54
2.24
1.74
1.2
1.2
—
—
—
0
0
61
443
1.40
1.71
1.5
1.7
0.19
0.33
mg/l
3.18
32
225
7
25
2.81
1.65
1.3
3.3
3.00
5.60
ug/l
—
7
25
516
4794
1.17
1.59
3.0
2.9
—
—
—
0
0
16
85
1.90
1.55
1.2
1.9
—
—
—
0
0
12
57
2.12
1.55
1.0
1.2
0.02
0.38
u/ml
—
6
32
15
78
1.94
1.55
1.1
2.0
—
—
—
0
0
18
100
1.82
1.54
1.2
1.1
—
—
—
0
0
39
267
1.48
1.51
1.4
1.6
12.62
11.46
u/ml
—
5
62
882
8614
1.33
1.50
39.3
24.4
243.94
244.26
e9/l
0.04
877
8463
9
37
2.45
1.48
1.1
1.8
—
—
—
0
0
9
37
2.45
1.48
1.1
1.8
—
—
—
0
0
9
37
2.45
1.48
1.1
1.8
—
—
—
0
0
9
37
2.45
1.48
1.1
1.8
—
—
—
0
0
9
37
2.45
1.48
1.7
2.0
—
—
—
0
0
882
8618
1.33
1.46
39.3
24.3
5.27
4.56
e12/l
137.80
874
8442
53
388
1.39
1.45
4.0
3.5
1.02
1.02
ratio
0.00
39
365
14
73
1.93
1.44
3.3
2.8
1139.93
1285.74
mg
0.14
14
73
13
67
1.95
1.38
1.3
1.5
75.92
82.10
umol/l
0.45
13
67
264
2349
1.17
1.38
1.8
1.7
17.91
19.75
nmol/l
1.48
226
1978
9
41
2.21
1.37
2.7
3.1
0.67
0.95
%
—
9
41
259
2303
1.17
1.37
3.3
3.0
0.72
0.73
ug/l
0.17
165
1388
105
856
1.25
1.36
3.9
4.7
4.42
23.98
ug/l
1.35
95
721
93
748
1.27
1.35
2.7
2.3
10.39
7.93
ug/l
0.28
78
672
82
650
1.29
1.34
2.2
2.0
—
—
—
0
0
48
352
1.38
1.32
1.0
1.1
—
—
—
0
0
15
83
1.82
1.32
1.1
1.4
10.60
26.24
u/l
2.61
15
67
44
321
1.39
1.25
1.6
1.9
7.01
6.66
iu/ml
—
7
80
76
945
0.79
1.21
2.1
2.1
4.12
3.67
ratio
1.07
62
768
13
71
1.84
1.19
1.1
1.6
—
—
—
0
0
13
71
1.84
1.19
1.1
1.6
—
—
—
0
0
13
71
1.84
1.19
1.1
1.6
—
—
—
0
0
6
26
2.32
1.19
1.2
1.3
14.17
9.04
ug/l
—
6
26
21
321
0.65
1.18
1.0
1.1
1.34
1.49
g/l
1.39
21
321
14
79
1.78
1.17
1.1
1.2
—
—
—
0
0
5
20
2.51
1.15
1.0
2.3
50.80
87.42
%
—
5
12
5
20
2.51
1.15
1.0
1.4
44.00
95.42
%
—
5
12
7
31
2.27
1.10
3.7
3.1
0.60
0.60
mmol/l
—
7
31
13
74
1.77
1.07
1.0
1.1
—
—
—
0
0
10
52
1.93
1.06
1.0
1.1
—
—
—
0
0
23
336
0.68
1.06
1.3
1.2
0.87
0.91
g/l
0.37
23
336
47
358
1.33
1.06
1.9
2.1
42.51
39.23
u/l
0.48
41
315
5
22
2.28
1.03
20.6
7.5
7.20
5.25
kpa
—
5
22
7
35
2.01
1.00
1.1
1.2
—
—
—
0
0
56
442
1.28
0.99
1.6
1.4
—
—
—
0
0
86
715
1.22
0.98
2.2
2.1
—
—
—
0
0
22
149
1.49
0.96
1.7
1.3
—
—
—
0
0
22
149
1.49
0.96
1.7
1.3
—
—
—
0
0
9
52
1.74
0.92
2.7
1.8
89.33
106.83
ng/l
—
9
52
8
42
1.91
0.88
2.0
2.5
67.25
100.07
%
—
8
42
8
42
1.91
0.88
1.4
1.1
—
—
—
0
0
17
111
1.54
0.88
1.0
1.1
0.66
1.29
u/ml
—
10
63
153
1354
1.15
0.88
1.3
1.3
6.46
10.40
u/ml
0.46
66
540
14
88
1.60
0.84
1.0
1.1
—
—
—
0
0
55
676
0.80
0.84
1.7
1.8
3.24
3.50
mmol/l
0.82
39
499
10
57
1.76
0.84
1.3
1.5
—
538.00
—
0
5
8
46
1.75
0.82
2.9
2.6
—
—
—
0
0
9
151
0.59
0.79
1.3
1.4
—
—
—
0
0
8
48
1.67
0.79
1.5
1.5
—
—
—
0
0
10
59
1.70
0.76
1.2
1.5
—
23.50
—
0
8
30
228
1.33
0.73
1.3
1.3
—
—
—
0
0
10
60
1.67
0.72
1.8
1.1
78.00
102.52
pmol/l
—
10
60
9
57
1.58
0.71
1.1
1.2
—
—
—
0
0
216
1988
1.11
0.68
2.7
2.4
—
—
—
0
0
7
42
1.67
0.68
1.1
1.1
179.34
252.46
iu/ml
—
7
42
12
78
1.55
0.65
2.4
1.8
—
—
—
0
0
28
215
1.31
0.65
1.3
1.2
—
2.95
—
0
13
5
29
1.73
0.64
1.0
2.0
—
—
—
0
0
5
29
1.73
0.64
1.0
2.0
—
—
—
0
0
66
563
1.19
0.63
2.4
2.5
25.18
19.39
au/ml
—
5
59
162
1477
1.12
0.62
1.3
1.3
17.34
30.22
iu/ml
3.68
49
440
31
244
1.28
0.62
1.6
1.4
—
—
—
0
0
5
30
1.67
0.61
1.0
1.9
—
—
—
0
0
5
30
1.67
0.61
2.4
1.8
80.40
58.38
ug/l
—
5
30
206
1907
1.10
0.59
4.2
3.9
1.02
1.02
kg/l
0.12
149
1285
42
346
1.22
0.58
2.4
3.9
122.80
4308.26
u/ml
0.82
35
295
25
193
1.30
0.58
1.1
1.6
—
—
—
0
0
36
292
1.24
0.57
2.9
2.7
22.23
81.32
u/ml
0.83
36
279
5
86
0.58
0.56
1.6
2.7
—
—
—
0
0
21
159
1.33
0.55
1.2
1.1
—
2.08
—
0
5
13
90
1.45
0.55
1.1
1.1
—
—
—
0
0
43
358
1.21
0.55
1.1
1.3
—
—
—
0
0
9
61
1.48
0.53
1.3
1.1
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
1796.83
1516.18
miu/ml
—
6
39
28
223
1.26
0.53
1.0
1.1
—
—
—
0
0
9
63
1.43
0.52
1.3
1.1
—
—
—
0
0
6
40
1.50
0.51
1.0
1.9
—
—
—
0
0
6
40
1.50
0.51
1.0
1.9
—
—
—
0
0
9
64
1.41
0.51
1.3
1.1
—
—
—
0
0
9
64
1.41
0.51
1.3
1.1
—
—
—
0
0
33
270
1.23
0.50
1.5
1.3
—
—
—
0
0
6
41
1.47
0.50
1.8
1.4
92.67
53.54
ug/l
—
6
41
91
1010
0.89
0.47
5.6
4.9
26.76
31.34
%
4.81
67
671
7
48
1.46
0.47
1.0
1.2
12.29
14.97
u/l
—
7
39
77
686
1.13
0.46
2.5
2.7
56.00
66.26
ml/min/173m2
1.51
35
278
7
50
1.40
0.45
1.0
1.2
62.00
76.17
u/l
—
7
42
27
220
1.23
0.44
1.0
1.1
—
—
—
0
0
5
31
1.62
0.43
2.8
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.3
116.60
111.65
nmol/l
—
5
26
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
9
70
1.29
0.36
1.3
1.1
—
—
—
0
0
6
43
1.40
0.35
2.7
1.6
—
964639.80
—
0
5
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
70
765
0.91
0.30
1.3
1.5
—
—
—
0
0
22
184
1.20
0.30
1.2
1.2
—
—
—
0
0
12
93
1.29
0.30
1.3
1.3
30960.00
17611.22
e6/l
—
5
49
36
316
1.14
0.29
2.4
3.0
—
—
—
0
0
7
56
1.25
0.29
1.1
1.2
—
—
—
0
0
21
248
0.84
0.28
1.1
1.3
—
—
—
0
0
13
103
1.27
0.28
1.4
1.3
3133.29
1760.53
e6/l
—
7
64
17
140
1.22
0.27
1.0
1.1
13.92
20.83
au/ml
—
5
40
9
75
1.20
0.25
1.3
1.2
—
—
—
0
0
33
293
1.13
0.24
2.4
2.4
—
—
—
0
0
19
162
1.18
0.23
1.4
1.2
—
1.02
—
0
9
0
10
0.00
0.21
0.0
3.0
—
76.71
—
0
10
13
156
0.83
0.21
1.4
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
27
240
1.13
0.20
1.4
1.6
14952.06
16777.18
e6/l
0.14
17
168
28
253
1.11
0.17
1.6
1.6
—
—
—
0
0
5
67
0.74
0.17
1.4
1.6
—
—
—
0
0
27
245
1.11
0.15
2.5
2.4
—
—
—
0
0
9
83
1.09
0.14
1.1
1.0
—
—
—
0
0
20
180
1.11
0.13
11.3
9.5
104.70
105.40
mmol/l
0.31
20
163
20
180
1.11
0.13
11.3
9.5
11.75
11.50
mmol/l
0.10
20
163
22
200
1.10
0.12
1.7
1.7
—
—
—
0
0
10
87
1.15
0.09
1.0
1.0
0.00
0.29
u/ml
—
5
39
6
55
1.09
0.09
1.7
1.5
—
—
—
0
0
6
56
1.07
0.08
1.2
1.2
—
—
—
0
0
10
112
0.89
0.07
1.1
1.4
—
—
—
0
0
10
111
0.90
0.06
1.1
1.4
—
—
—
0
0
12
109
1.10
0.06
1.2
1.1
17.34
2.70
eliau/ml
—
5
42
10
111
0.90
0.06
1.1
1.4
—
—
—
0
0
10
90
1.11
0.05
2.9
3.9
—
—
—
0
0
14
132
1.06
0.02
1.1
1.5
—
—
—
0
0
25
257
0.97
0.01
1.7
1.5
0.02
0.12
iu/ml
—
7
44
93
937
0.99
0.01
10.8
7.0
—
—
—
0
0
12
114
1.05
0.00
1.3
1.4
—
—
—
0
0
12
116
1.03
0.00
1.3
1.4
—
—
—
0
0
12
116
1.03
0.00
1.3
1.4
—
—
—
0
0
7
74
0.95
0.00
1.3
1.2
—
79.00
—
0
6
5
49
1.02
-0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
64
0.94
-0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
13.00
—
0
5
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
419.00
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_SCNDPOLYCYTHAEMIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDPOLYCYTHAEMIA | 2.337 [1.94, 2.81] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.556 |
During the follow-up period (1.1.1998 — 31.12.2019), 330 out of 1298 females with D3_SCNDPOLYCYTHAEMIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_SCNDPOLYCYTHAEMIA | 1.929 [1.65, 2.25] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 574 out of 2522 males with D3_SCNDPOLYCYTHAEMIA died.
Mortality risk
Mortality risk for people of age
years, who have D3_SCNDPOLYCYTHAEMIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.314% | 0.369% |
| 5 | 1.509% | 2.132% |
| 10 | 3.477% | 5.162% |
| 15 | 6.641% | 10.023% |
| 20 | 12.368% | 16.089% |
Relationships between endpoints
↥Index endpoint: D3_SCNDPOLYCYTHAEMIA – Secondary polycythaemia
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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