Silver Birch IgE Ab [Units/volume] in Serum

Number of people
1 431 (73.03% female)
People with ≥2 records
4.68%
Median duration from first to last measurement
1.36 years

Coding

Definition

OMOP Concept ID
3027300— open in OHDSI Athena.
Part of collection
Silver Birch (Betula verrucosa) IgE with 0 other OMOP concept — open in OHDSI Athena.

OMOP mapping QC

OMOP concept ID Test name Measurement unit (harmonized unit) N people N records Missing measurement value Harmonized value distribution
Test outcome
NA
N
A
AA
L
LL
H
HH
3027300 koivu — (—) 621 650 100.00% Distribution not available
3027300 igekoivu u/ml (—) 236 240 100.00% Distribution not available
3027300 koivu u/ml (u/ml) 197 204 0.00%
3027300 koivue u/ml (—) 166 179 100.00% Distribution not available
3027300 s-koivunsiitepöly,igevasta-aineet u/ml (—) 149 150 100.00% Distribution not available
3027300 s-allige,koivu/björk u/ml (—) 76 76 100.00% Distribution not available

Cohort

Number of people
1 431 (73.03% female)

Year of birth distribution

Age at first measurement

Age at last measurement

Age at start of registry

Duration from first to last measurement

Statistics

People with ≥2 records
4.68%
Median number of measurements per person
1.0
Median duration from first to last measurement
1.36 years

Number of measurements over the years

Number of measurements per person

Distribution of lab values

Value range per person

No data available for the distribution of value range per person.

LabWAS

Endpoint
People with measurements
Mean N measurements
Mean measured value
Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
433
455
9.66
307.65
1.1
1.0
10.89
9.17
u/ml
0.24
95
42
363
316
11.79
307.65
1.1
1.0
11.68
7.54
u/ml
0.73
84
27
449
454
9.94
307.65
1.1
1.0
10.83
15.86
u/ml
0.53
98
28
423
348
6.72
201.40
1.1
1.0
9.66
10.92
u/ml
0.09
98
17
427
347
6.65
198.88
1.1
1.0
9.68
10.92
u/ml
0.09
99
17
390
347
6.83
197.77
1.1
1.0
9.46
10.92
u/ml
0.10
97
17
424
344
6.62
196.09
1.1
1.0
9.52
10.92
u/ml
0.10
98
17
389
344
6.78
194.92
1.1
1.0
9.55
10.92
u/ml
0.10
96
17
584
835
4.09
173.87
1.1
1.0
10.32
12.11
u/ml
0.32
111
82
204
228
8.90
162.25
1.1
1.0
11.53
5.04
u/ml
—
60
9
204
228
8.90
162.22
1.1
1.0
11.53
5.04
u/ml
—
60
9
157
145
10.91
144.80
1.1
1.0
11.60
5.15
u/ml
—
50
8
438
951
3.96
144.14
1.1
1.0
9.84
13.25
u/ml
0.71
107
79
157
150
10.55
141.46
1.1
1.0
11.60
5.15
u/ml
—
50
8
133
115
12.21
130.83
1.1
1.0
14.72
6.12
u/ml
—
38
9
545
866
3.42
124.71
1.1
1.0
9.60
13.03
u/ml
0.75
110
82
366
775
4.06
124.32
1.1
1.0
11.47
10.28
u/ml
0.19
70
89
405
989
3.69
122.33
1.1
1.0
9.82
12.60
u/ml
0.58
99
90
431
865
3.53
113.51
1.1
1.0
8.38
13.03
u/ml
1.14
91
82
471
922
3.36
112.86
1.1
1.0
11.03
9.84
u/ml
0.20
78
112
317
798
3.94
107.76
1.1
1.0
13.40
9.82
u/ml
0.64
56
94
321
849
3.75
101.94
1.0
1.0
13.48
9.66
u/ml
0.72
57
98
409
599
3.57
98.39
1.1
1.0
8.11
13.09
u/ml
0.89
62
48
371
979
3.32
95.05
1.1
1.0
12.73
10.33
u/ml
0.42
64
120
199
291
5.45
93.42
1.1
1.0
8.81
12.03
u/ml
0.20
43
14
199
288
5.45
93.15
1.1
1.0
8.81
12.03
u/ml
0.20
43
14
377
995
3.19
89.57
1.1
1.0
12.73
10.28
u/ml
0.44
64
121
226
522
4.24
84.62
1.1
1.0
12.47
8.80
u/ml
0.63
51
59
173
372
4.68
74.34
1.1
1.0
8.38
15.48
u/ml
0.76
32
30
242
664
3.60
72.86
1.1
1.0
11.61
12.33
u/ml
0.09
61
53
242
664
3.60
72.86
1.1
1.0
11.61
12.33
u/ml
0.09
61
53
270
356
3.81
69.80
1.0
1.0
9.21
10.92
u/ml
0.11
40
17
266
348
3.84
69.45
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
266
348
3.84
69.45
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
265
356
3.74
66.91
1.0
1.0
9.42
10.92
u/ml
0.10
39
17
209
559
3.73
66.40
1.1
1.0
11.45
11.73
u/ml
0.03
54
46
216
601
3.56
63.51
1.1
1.0
13.14
7.56
u/ml
1.19
47
64
72
79
9.21
59.52
1.1
1.0
11.38
6.58
u/ml
—
24
7
131
276
4.78
57.88
1.1
1.0
8.51
9.07
u/ml
0.06
32
21
391
879
2.52
54.70
1.1
1.0
9.25
12.51
u/ml
0.71
84
91
143
340
4.13
52.24
1.1
1.0
14.56
8.42
u/ml
0.98
40
38
90
153
5.96
50.59
1.1
1.0
8.82
4.84
u/ml
0.66
12
17
345
814
2.53
49.29
1.1
1.0
9.47
9.70
u/ml
0.03
53
92
356
885
2.44
47.67
1.1
1.0
7.98
11.85
u/ml
1.11
85
92
118
271
4.38
46.93
1.1
1.0
9.67
14.57
u/ml
0.40
20
19
197
279
3.55
46.59
1.0
1.0
5.36
6.08
u/ml
0.11
25
11
384
822
2.35
44.82
1.1
1.0
12.45
9.60
u/ml
0.53
61
93
254
585
2.76
43.79
1.1
1.0
10.55
13.35
u/ml
0.33
37
47
68
101
6.78
43.58
1.1
1.0
6.51
12.48
u/ml
—
11
10
384
935
2.26
42.36
1.1
1.0
9.41
12.72
u/ml
0.72
80
95
97
207
4.70
42.25
1.1
1.0
7.16
16.49
u/ml
0.77
16
18
101
170
4.76
41.04
1.0
1.0
13.54
5.66
u/ml
—
23
9
101
171
4.73
40.79
1.0
1.0
13.54
5.66
u/ml
—
23
9
375
914
2.24
40.63
1.1
1.0
9.99
12.08
u/ml
0.38
75
95
170
561
3.05
39.52
1.1
1.0
8.97
9.83
u/ml
0.11
29
68
113
294
3.88
38.17
1.1
1.0
12.27
6.37
u/ml
0.62
16
36
373
980
2.17
37.72
1.1
1.0
8.76
12.60
u/ml
0.98
82
103
151
485
3.14
36.83
1.1
1.0
8.66
7.96
u/ml
0.08
25
65
211
384
2.82
35.55
1.0
1.0
10.53
10.92
u/ml
0.04
29
46
138
410
3.24
35.38
1.1
1.0
14.41
10.00
u/ml
0.51
28
47
69
132
5.28
34.29
1.1
1.0
2.48
4.99
u/ml
1.02
14
17
318
711
2.25
33.90
1.0
1.0
11.50
9.63
u/ml
0.26
46
88
69
138
5.05
32.62
1.1
1.0
2.48
4.73
u/ml
0.92
14
18
194
677
2.55
31.46
1.1
1.1
6.75
11.20
u/ml
1.19
44
82
245
826
2.28
30.18
1.1
1.0
9.88
10.48
u/ml
0.09
42
107
127
298
3.20
29.87
1.1
1.0
11.23
11.09
u/ml
0.01
23
35
99
281
3.55
29.55
1.0
1.0
10.09
7.94
u/ml
0.22
19
36
133
460
2.91
28.63
1.1
1.0
12.28
8.92
u/ml
0.29
16
63
192
536
2.38
25.27
1.1
1.0
12.88
13.65
u/ml
0.06
26
63
24
20
12.58
24.01
1.1
1.0
7.52
4.58
u/ml
—
12
6
126
378
2.77
23.71
1.0
1.0
17.39
13.03
u/ml
0.33
22
34
60
117
4.44
23.42
1.1
1.1
8.17
9.24
u/ml
—
14
10
297
961
1.94
23.27
1.1
1.0
9.46
9.83
u/ml
0.05
46
123
292
747
1.96
22.34
1.0
1.0
10.20
10.43
u/ml
0.03
42
89
43
77
5.50
21.93
1.0
1.0
17.55
4.30
u/ml
—
8
6
84
264
3.19
21.38
1.1
1.0
8.40
9.21
u/ml
0.09
22
23
84
264
3.19
21.38
1.1
1.0
8.40
9.21
u/ml
0.09
22
23
36
59
6.15
21.09
1.1
1.1
2.32
3.99
u/ml
—
6
7
83
262
3.17
20.98
1.1
1.0
8.40
9.35
u/ml
0.10
22
22
311
884
1.86
20.74
1.1
1.0
9.96
9.66
u/ml
0.04
44
113
300
1072
1.84
20.30
1.1
1.0
11.83
10.90
u/ml
0.10
44
146
215
719
2.03
19.63
1.0
1.1
10.14
10.00
u/ml
0.02
43
94
147
382
2.34
18.52
1.1
1.0
6.39
11.15
u/ml
0.79
24
45
225
771
1.90
16.84
1.0
1.1
8.98
10.02
u/ml
0.16
43
100
227
910
1.87
16.84
1.1
1.0
12.46
10.02
u/ml
0.28
38
113
163
384
2.13
15.70
1.0
1.0
6.84
10.92
u/ml
0.63
17
46
289
831
1.74
15.61
1.1
1.0
10.46
9.80
u/ml
0.09
43
109
289
831
1.74
15.61
1.1
1.0
10.46
9.80
u/ml
0.09
43
109
135
629
2.15
15.59
1.1
1.0
9.84
8.06
u/ml
0.20
26
76
105
446
2.31
14.44
1.1
1.0
8.22
9.30
u/ml
0.15
14
57
232
646
1.80
14.05
1.1
1.0
8.68
12.93
u/ml
0.64
39
61
236
1090
1.71
13.22
1.1
1.0
11.40
10.97
u/ml
0.05
26
148
214
984
1.75
13.15
1.0
1.0
7.73
12.44
u/ml
1.16
34
130
145
710
1.95
12.89
1.1
1.0
8.04
11.30
u/ml
0.64
16
89
235
1092
1.69
12.72
1.1
1.0
11.40
10.90
u/ml
0.06
26
149
236
908
1.71
12.67
1.0
1.0
9.23
10.92
u/ml
0.29
45
112
208
942
1.74
12.52
1.0
1.0
7.89
12.46
u/ml
1.08
33
115
254
928
1.66
12.29
1.1
1.0
10.03
10.23
u/ml
0.03
57
111
231
1097
1.68
12.07
1.1
1.0
10.69
10.97
u/ml
0.03
28
148
49
128
3.16
11.93
1.1
1.1
6.64
13.22
u/ml
—
15
10
218
897
1.70
11.65
1.1
1.0
8.86
11.06
u/ml
0.33
28
117
277
1075
1.60
11.49
1.1
1.0
12.06
10.75
u/ml
0.19
55
131
251
1095
1.63
11.49
1.1
1.0
7.50
12.31
u/ml
1.48
41
145
250
1094
1.63
11.45
1.1
1.0
7.50
12.31
u/ml
1.48
41
145
153
781
1.83
11.19
1.1
1.0
10.78
9.19
u/ml
0.25
35
102
302
987
1.57
11.18
1.1
1.0
9.09
12.35
u/ml
0.64
46
120
226
912
1.65
10.72
1.1
1.0
7.66
11.76
u/ml
1.06
37
116
224
915
1.64
10.62
1.1
1.0
12.23
10.92
u/ml
0.13
31
123
309
1019
1.54
10.43
1.1
1.0
6.25
12.25
u/ml
2.82
41
145
44
119
3.08
10.32
1.1
1.1
6.63
13.22
u/ml
—
12
10
130
502
1.88
9.86
1.1
1.0
8.75
13.61
u/ml
0.64
24
60
200
610
1.65
9.02
1.1
1.0
4.84
12.16
u/ml
2.22
24
67
70
317
2.22
8.91
1.1
1.0
3.86
11.16
u/ml
—
7
47
181
907
1.64
8.86
1.1
1.0
6.84
12.00
u/ml
1.64
24
119
186
560
1.67
8.81
1.0
1.0
12.53
13.62
u/ml
0.09
24
64
230
1003
1.55
8.78
1.1
1.0
8.94
11.34
u/ml
0.28
29
140
63
275
2.30
8.75
1.0
1.0
27.08
6.11
u/ml
—
10
28
64
274
2.28
8.69
1.1
1.1
8.35
9.71
u/ml
0.08
15
33
203
787
1.60
8.69
1.1
1.0
10.60
10.81
u/ml
0.02
23
110
35
114
3.09
8.66
1.1
1.0
4.13
5.01
u/ml
—
8
13
171
569
1.68
8.66
1.0
1.0
10.92
13.08
u/ml
0.22
30
70
181
940
1.61
8.37
1.1
1.0
11.93
10.08
u/ml
0.14
18
124
74
351
2.11
8.34
1.1
1.0
8.33
7.02
u/ml
0.19
14
37
98
524
1.87
7.97
1.1
1.0
11.00
8.57
u/ml
0.23
21
65
74
356
2.06
7.93
1.1
1.0
11.36
8.35
u/ml
0.30
12
44
288
1022
1.46
7.92
1.1
1.0
7.48
10.17
u/ml
0.61
40
136
250
843
1.49
7.59
1.1
1.0
6.47
12.52
u/ml
1.75
34
101
229
939
1.51
7.57
1.1
1.0
6.17
11.36
u/ml
1.56
27
131
183
706
1.59
7.55
1.1
1.0
11.39
10.45
u/ml
0.10
32
82
66
148
2.25
7.50
1.0
1.0
6.93
17.08
u/ml
—
8
15
71
349
2.04
7.40
1.0
1.1
14.72
8.43
u/ml
0.50
14
44
182
573
1.60
7.38
1.1
1.0
8.24
11.48
u/ml
0.49
24
71
39
137
2.65
7.30
1.1
1.1
8.11
6.61
u/ml
—
8
15
77
393
1.96
7.24
1.1
1.0
7.81
8.43
u/ml
0.06
18
53
124
354
1.76
7.24
1.1
1.0
5.38
13.81
u/ml
1.85
15
36
241
1130
1.47
7.21
1.0
1.0
9.85
11.52
u/ml
0.25
47
144
150
827
1.61
7.08
1.0
1.0
8.62
12.17
u/ml
0.53
21
111
104
591
1.76
6.98
1.1
1.0
12.22
11.24
u/ml
0.08
14
67
23
66
3.50
6.98
1.0
1.0
3.56
20.39
u/ml
—
5
8
264
913
1.45
6.92
1.1
1.0
11.84
10.25
u/ml
0.19
36
122
130
698
1.65
6.83
1.1
1.0
7.32
11.54
u/ml
0.92
19
87
118
705
1.68
6.66
1.1
1.0
5.52
11.26
u/ml
1.71
23
90
153
825
1.58
6.65
1.1
1.0
7.51
12.28
u/ml
1.03
22
98
240
825
1.46
6.65
1.0
1.0
6.67
13.30
u/ml
2.05
27
107
255
943
1.44
6.62
1.0
1.0
12.46
10.71
u/ml
0.20
38
127
109
596
1.71
6.57
1.1
1.0
6.51
10.72
u/ml
0.85
15
73
247
1133
1.44
6.53
1.0
1.0
10.28
11.52
u/ml
0.18
47
144
247
1133
1.43
6.48
1.0
1.0
10.28
11.52
u/ml
0.18
47
144
70
171
2.06
6.47
1.1
1.0
5.23
8.22
u/ml
—
8
14
239
825
1.45
6.39
1.0
1.0
7.44
13.30
u/ml
1.57
26
107
116
592
1.67
6.31
1.0
1.0
19.79
9.20
u/ml
0.90
17
68
146
929
1.57
6.28
1.0
1.1
13.88
9.88
u/ml
0.42
22
124
220
918
1.46
6.28
1.1
1.0
10.00
11.65
u/ml
0.23
43
118
81
445
1.82
6.16
1.1
1.1
13.15
9.41
u/ml
0.31
16
60
79
433
1.83
6.04
1.0
1.0
9.68
10.19
u/ml
—
8
49
35
140
2.51
6.00
1.1
1.1
4.96
5.91
u/ml
—
10
16
170
869
1.51
5.97
1.1
1.0
8.84
10.94
u/ml
0.25
25
121
29
101
2.76
5.95
1.0
1.0
—
6.97
—
0
15
37
153
2.42
5.92
1.0
1.1
12.22
10.07
u/ml
—
5
17
186
1155
1.47
5.88
1.1
1.0
13.82
10.87
u/ml
0.28
25
155
156
1008
1.51
5.79
1.1
1.0
8.96
10.35
u/ml
0.17
30
134
254
962
1.39
5.55
1.0
1.0
11.15
11.32
u/ml
0.02
38
128
44
203
2.18
5.52
1.1
1.1
10.27
5.58
u/ml
—
10
34
24
83
2.90
5.45
1.0
1.1
11.65
4.21
u/ml
—
6
8
211
970
1.42
5.41
1.0
1.1
9.68
10.45
u/ml
0.12
27
134
147
968
1.51
5.37
1.1
1.0
5.85
11.18
u/ml
1.83
27
129
79
217
1.83
5.36
1.0
1.0
7.49
13.61
u/ml
—
8
23
79
217
1.83
5.36
1.0
1.0
7.49
13.61
u/ml
—
8
23
175
1131
1.45
5.30
1.1
1.0
12.14
10.93
u/ml
0.13
30
143
147
972
1.50
5.25
1.1
1.0
5.85
11.10
u/ml
1.79
27
130
259
979
1.38
5.24
1.0
1.0
5.77
11.69
u/ml
2.57
32
134
114
647
1.59
5.23
1.1
1.0
10.38
9.98
u/ml
0.04
21
89
262
977
1.37
5.16
1.0
1.0
9.52
11.24
u/ml
0.24
34
129
124
803
1.55
5.13
1.0
1.0
9.10
11.73
u/ml
0.36
17
100
26
98
2.66
5.07
1.0
1.0
5.88
6.24
u/ml
—
5
13
158
843
1.47
5.02
1.1
1.0
12.74
8.66
u/ml
0.60
29
109
60
325
1.85
4.87
1.1
1.1
8.60
6.18
u/ml
0.22
11
43
89
264
1.71
4.84
1.1
1.0
6.64
18.22
u/ml
1.60
12
32
171
786
1.44
4.78
1.1
1.0
8.77
9.92
u/ml
0.17
24
113
129
865
1.49
4.57
1.0
1.0
8.70
11.79
u/ml
0.41
21
108
39
172
2.11
4.53
1.0
1.0
21.57
15.34
u/ml
—
6
15
89
475
1.62
4.48
1.0
1.0
10.92
12.64
u/ml
0.14
12
51
37
175
2.12
4.42
1.1
1.0
3.49
9.50
u/ml
—
5
23
50
264
1.90
4.42
1.1
1.0
11.22
8.62
u/ml
0.18
12
26
80
989
0.62
4.40
1.0
1.1
18.61
9.18
u/ml
1.14
15
123
237
952
1.35
4.37
1.1
1.0
9.65
11.32
u/ml
0.24
37
128
162
756
1.43
4.36
1.1
1.1
5.99
10.98
u/ml
1.35
20
98
217
813
1.36
4.24
1.0
1.0
9.14
13.07
u/ml
0.45
22
104
59
333
1.77
4.24
1.0
1.0
11.97
8.71
u/ml
—
9
37
220
1188
1.34
4.17
1.1
1.0
15.25
10.06
u/ml
0.67
34
161
104
614
1.53
4.15
1.1
1.1
7.69
11.13
u/ml
0.56
13
87
50
270
1.86
4.15
1.1
1.0
9.40
7.33
u/ml
—
9
38
99
445
1.56
4.11
1.1
1.0
6.82
10.45
u/ml
0.57
11
59
63
188
1.79
4.11
1.2
1.0
5.92
14.21
u/ml
1.32
14
22
263
1001
1.32
4.10
1.1
1.0
11.79
10.05
u/ml
0.20
30
135
225
838
1.35
4.10
1.0
1.1
7.86
12.18
u/ml
1.06
29
94
225
838
1.35
4.10
1.0
1.1
7.86
12.18
u/ml
1.06
29
94
42
215
1.96
4.09
1.0
1.0
10.82
11.89
u/ml
—
5
26
232
882
1.34
4.07
1.1
1.0
9.50
12.26
u/ml
0.32
28
114
90
822
0.65
4.03
1.0
1.1
15.10
9.72
u/ml
—
8
120
86
507
1.58
4.00
1.1
1.0
18.43
10.54
u/ml
—
9
63
112
377
1.53
4.00
1.1
1.1
5.37
9.89
u/ml
1.05
16
54
44
193
1.93
3.99
1.1
1.0
6.63
7.80
u/ml
0.13
12
23
210
1218
1.34
3.96
1.1
1.0
5.97
11.81
u/ml
2.08
30
166
129
440
1.48
3.94
1.0
1.0
10.57
12.55
u/ml
0.14
17
61
48
259
1.85
3.93
1.1
1.0
18.11
8.02
u/ml
0.59
11
29
54
305
1.77
3.90
1.1
1.0
8.44
10.11
u/ml
0.12
11
39
91
822
0.65
3.89
1.0
1.1
15.10
9.72
u/ml
—
8
120
205
1194
1.34
3.85
1.0
1.0
7.82
11.51
u/ml
0.85
28
165
93
608
1.53
3.81
1.1
1.0
11.01
9.40
u/ml
0.14
16
69
62
367
1.69
3.81
1.0
1.0
9.95
9.69
u/ml
0.02
12
46
34
138
2.08
3.79
1.1
1.1
5.53
6.22
u/ml
—
10
19
57
331
1.72
3.76
1.1
1.0
9.40
8.74
u/ml
—
9
47
55
317
1.74
3.73
1.1
1.0
14.11
7.09
u/ml
—
9
51
54
255
1.76
3.73
1.1
1.1
6.14
11.26
u/ml
0.71
13
34
188
918
1.35
3.73
1.1
1.1
8.77
10.58
u/ml
0.29
24
128
140
738
1.42
3.72
1.0
1.0
7.37
12.19
u/ml
0.93
20
96
116
400
1.49
3.70
1.1
1.1
4.19
10.23
u/ml
1.97
15
58
46
253
1.82
3.65
1.1
1.0
3.28
9.20
u/ml
—
9
34
68
648
0.62
3.65
1.0
1.1
11.29
9.60
u/ml
0.18
11
87
43
194
1.88
3.65
1.1
1.0
6.63
7.80
u/ml
0.13
12
23
48
268
1.79
3.63
1.0
1.0
8.03
8.99
u/ml
—
9
32
71
443
1.61
3.58
1.1
1.1
3.40
14.39
u/ml
3.37
15
54
27
124
2.18
3.53
1.0
1.0
7.69
15.17
u/ml
—
8
13
177
895
1.35
3.51
1.1
1.1
9.76
10.23
u/ml
0.06
24
128
22
300
0.45
3.49
1.0
1.0
—
10.98
—
0
37
49
280
1.75
3.45
1.0
1.0
17.93
9.93
u/ml
—
9
33
64
397
1.62
3.34
1.0
1.1
20.43
7.40
u/ml
—
8
51
82
539
1.52
3.32
1.1
1.0
18.47
8.01
u/ml
0.81
14
65
223
903
1.30
3.30
1.1
1.0
7.61
12.44
u/ml
1.10
35
116
190
949
1.32
3.29
1.1
1.1
8.77
10.71
u/ml
0.31
24
132
49
285
1.72
3.26
1.0
1.1
6.10
10.88
u/ml
—
7
45
156
572
1.37
3.22
1.1
1.0
10.30
12.60
u/ml
0.17
17
67
91
791
0.68
3.22
1.0
1.1
17.07
9.75
u/ml
—
7
116
77
445
1.52
3.05
1.1
1.1
10.18
7.64
u/ml
0.26
14
68
163
624
1.34
3.00
1.0
1.0
8.51
10.75
u/ml
0.27
19
84
22
100
2.20
2.98
1.0
1.1
7.51
5.32
u/ml
—
6
11
236
929
1.27
2.97
1.1
1.0
11.99
11.56
u/ml
0.04
35
119
236
945
1.27
2.96
1.1
1.0
12.11
10.71
u/ml
0.14
32
127
32
579
0.55
2.93
1.1
1.0
4.90
9.35
u/ml
—
9
75
46
265
1.70
2.91
1.0
1.0
2.53
12.36
u/ml
—
5
29
45
265
1.70
2.90
1.1
1.0
7.15
8.87
u/ml
—
9
33
26
128
2.04
2.90
1.0
1.1
19.53
5.58
u/ml
—
6
15
107
524
1.41
2.90
1.1
1.0
6.68
11.17
u/ml
0.82
15
71
234
924
1.27
2.89
1.1
1.0
11.99
11.64
u/ml
0.03
35
118
64
410
1.55
2.88
1.0
1.1
3.04
10.51
u/ml
—
8
57
32
171
1.87
2.84
1.1
1.0
2.27
11.30
u/ml
—
6
24
111
909
0.72
2.84
1.0
1.1
15.64
10.01
u/ml
—
10
134
126
751
1.36
2.81
1.0
1.1
6.85
9.47
u/ml
0.29
11
101
48
291
1.65
2.80
1.0
1.0
5.60
9.27
u/ml
—
5
33
41
239
1.72
2.76
1.0
1.0
6.22
8.42
u/ml
—
8
31
42
247
1.70
2.74
1.0
1.0
6.22
8.87
u/ml
—
8
32
41
662
0.60
2.74
1.1
1.0
2.33
10.26
u/ml
—
8
86
52
325
1.60
2.70
1.1
1.0
4.41
12.13
u/ml
—
9
43
43
254
1.68
2.70
1.1
1.1
9.81
8.10
u/ml
—
7
36
157
947
1.31
2.69
1.1
1.0
8.37
10.00
u/ml
0.15
22
125
74
491
1.48
2.67
1.0
1.1
2.75
10.74
u/ml
—
9
66
10
32
3.14
2.64
1.0
1.1
—
4.59
—
0
6
174
687
1.30
2.64
1.0
1.1
8.17
10.38
u/ml
0.26
19
88
21
99
2.12
2.64
1.1
1.1
13.05
3.91
u/ml
—
7
11
21
99
2.12
2.64
1.1
1.1
13.05
3.91
u/ml
—
7
11
59
385
1.54
2.57
1.0
1.1
5.70
9.58
u/ml
—
7
59
138
782
1.32
2.55
1.1
1.0
8.38
9.17
u/ml
0.10
25
99
187
732
1.28
2.53
1.0
1.0
10.94
9.55
u/ml
0.13
23
94
216
898
1.26
2.52
1.1
1.0
10.32
12.44
u/ml
0.24
31
116
17
75
2.27
2.50
1.0
1.1
—
4.50
—
0
8
110
700
1.36
2.50
1.1
1.0
13.17
12.60
u/ml
0.04
11
85
56
751
0.66
2.50
1.0
1.1
14.31
8.94
u/ml
0.44
11
99
78
396
1.45
2.48
1.1
1.0
7.17
10.53
u/ml
0.61
13
50
39
202
1.69
2.47
1.1
1.0
9.69
6.50
u/ml
—
5
20
74
511
1.45
2.46
1.1
1.0
19.67
11.50
u/ml
0.45
11
63
56
755
0.66
2.46
1.1
1.0
7.66
10.30
u/ml
0.26
11
96
46
284
1.60
2.42
1.0
1.0
2.53
9.15
u/ml
—
5
39
154
864
1.29
2.38
1.0
1.0
4.99
10.37
u/ml
2.71
18
115
51
712
0.66
2.37
1.1
1.0
8.36
10.21
u/ml
—
10
92
34
198
1.72
2.34
1.1
1.0
4.65
12.35
u/ml
—
7
29
185
732
1.27
2.33
1.0
1.0
12.13
9.55
u/ml
0.23
20
94
49
314
1.56
2.33
1.1
1.0
11.77
9.12
u/ml
—
8
36
91
654
1.38
2.31
1.1
1.0
17.56
10.31
u/ml
0.48
14
86
100
652
1.36
2.31
1.1
1.0
11.32
9.72
u/ml
0.12
17
78
43
268
1.61
2.30
1.1
1.0
9.81
7.87
u/ml
—
7
33
31
177
1.75
2.29
1.1
1.0
6.44
9.34
u/ml
—
7
20
43
269
1.60
2.28
1.1
1.0
7.60
8.65
u/ml
—
5
33
26
120
1.85
2.22
1.2
1.1
6.89
5.77
u/ml
—
6
16
70
488
1.43
2.22
1.1
1.0
17.52
10.92
u/ml
—
10
62
25
136
1.84
2.17
1.1
1.0
27.83
4.78
u/ml
—
7
16
140
552
1.30
2.16
1.1
1.0
5.26
10.12
u/ml
1.26
16
75
140
552
1.30
2.16
1.1
1.0
5.26
10.12
u/ml
1.26
16
75
52
348
1.50
2.08
1.1
1.1
8.70
9.82
u/ml
—
6
47
24
131
1.83
2.07
1.0
1.1
7.51
8.07
u/ml
—
6
18
27
153
1.77
2.07
1.1
1.0
9.55
10.20
u/ml
—
6
20
27
153
1.77
2.07
1.1
1.1
8.27
4.83
u/ml
—
8
21
27
153
1.77
2.07
1.0
1.0
9.38
6.34
u/ml
—
6
15
50
477
0.67
2.06
1.0
1.0
7.62
10.71
u/ml
—
5
66
187
1079
1.23
2.04
1.1
1.0
7.11
10.65
u/ml
0.85
31
149
33
199
1.66
2.04
1.1
1.0
1.84
7.63
u/ml
—
5
28
46
465
0.66
2.04
1.0
1.0
3.30
10.96
u/ml
—
8
59
140
558
1.28
2.02
1.1
1.0
4.08
10.19
u/ml
2.13
15
77
18
90
2.00
2.00
1.2
1.0
4.17
4.92
u/ml
—
5
11
46
299
1.52
1.99
1.0
1.0
2.53
9.15
u/ml
—
5
39
36
132
1.64
1.97
1.1
1.0
6.16
9.74
u/ml
—
5
16
64
449
1.42
1.97
1.1
1.1
12.03
11.18
u/ml
—
10
63
46
683
0.67
1.97
1.0
1.0
4.54
9.99
u/ml
—
10
94
60
810
0.71
1.96
1.1
1.0
2.71
10.96
u/ml
—
9
110
200
1140
1.22
1.94
1.1
1.0
8.39
10.85
u/ml
0.35
28
161
95
607
1.33
1.93
1.1
1.0
9.33
8.65
u/ml
0.06
13
79
98
889
0.76
1.93
1.0
1.0
24.98
8.82
u/ml
1.11
13
120
127
808
1.28
1.91
1.0
1.0
6.46
10.02
u/ml
0.72
17
112
80
590
1.36
1.91
1.0
1.0
6.68
9.54
u/ml
0.31
12
82
63
828
0.72
1.90
1.1
1.0
2.75
11.07
u/ml
—
10
111
183
937
1.23
1.90
1.1
1.0
6.98
10.95
u/ml
1.13
24
130
141
683
1.26
1.89
1.1
1.1
8.33
10.61
u/ml
0.21
21
101
45
301
1.50
1.84
1.0
1.0
17.61
8.56
u/ml
—
7
32
163
827
1.24
1.81
1.1
1.0
7.44
9.80
u/ml
0.61
27
109
163
827
1.24
1.81
1.1
1.0
7.44
9.80
u/ml
0.61
27
109
44
293
1.50
1.81
1.1
1.0
32.00
9.28
u/ml
—
5
38
77
568
1.35
1.80
1.1
1.0
10.18
8.97
u/ml
0.11
14
80
9
35
2.58
1.80
1.0
1.0
—
3.13
—
0
7
52
360
1.45
1.80
1.1
1.1
8.66
8.53
u/ml
—
8
48
95
727
1.31
1.78
1.1
1.0
4.83
10.23
u/ml
—
9
98
208
973
1.20
1.76
1.1
1.0
6.73
11.42
u/ml
1.20
34
123
115
915
0.79
1.76
1.0
1.1
9.27
9.71
u/ml
0.04
19
117
83
625
1.33
1.75
1.0
1.1
6.68
10.17
u/ml
0.40
12
83
18
95
1.90
1.75
1.1
1.0
—
6.87
—
0
11
46
383
0.69
1.74
1.1
1.0
3.03
13.65
u/ml
—
6
45
84
634
1.33
1.74
1.1
1.0
5.43
10.29
u/ml
0.98
11
84
48
330
1.46
1.73
1.0
1.0
20.56
9.73
u/ml
—
5
42
38
249
1.53
1.72
1.1
1.0
7.20
9.39
u/ml
—
6
31
32
202
1.58
1.70
1.0
1.0
6.45
9.78
u/ml
—
8
28
0
49
0.00
1.68
0.0
1.0
—
4.59
—
0
7
63
541
0.73
1.66
1.0
1.0
8.97
10.48
u/ml
—
9
67
25
149
1.68
1.66
1.0
1.0
11.34
4.39
u/ml
—
5
18
135
1051
1.24
1.65
1.0
1.0
8.13
10.65
u/ml
0.58
22
142
141
1040
1.23
1.65
1.0
1.0
6.72
11.00
u/ml
1.03
20
136
85
616
1.31
1.63
1.1
1.1
6.88
10.06
u/ml
—
10
79
26
415
0.63
1.62
1.0
1.0
22.00
11.15
u/ml
—
6
43
227
1117
1.18
1.61
1.1
1.0
10.30
10.40
u/ml
0.01
36
150
7
26
2.70
1.58
1.1
1.0
—
3.61
—
0
5
32
484
0.66
1.57
1.1
1.0
2.15
12.01
u/ml
—
6
61
81
615
1.31
1.56
1.0
1.0
20.52
10.20
u/ml
—
10
76
105
821
0.79
1.54
1.1
1.0
7.06
10.84
u/ml
0.54
17
108
109
669
1.26
1.54
1.1
1.0
11.02
10.66
u/ml
0.02
14
91
124
508
1.25
1.53
1.1
1.0
4.80
10.67
u/ml
1.77
14
68
48
422
0.71
1.53
1.0
1.0
6.91
10.56
u/ml
—
5
60
150
627
1.22
1.53
1.0
1.0
3.46
9.82
u/ml
2.45
16
81
112
684
1.25
1.52
1.1
1.1
6.32
10.05
u/ml
0.84
15
90
65
473
1.34
1.51
1.0
1.0
9.92
12.81
u/ml
—
8
51
40
275
1.46
1.48
1.0
1.1
4.84
5.66
u/ml
—
6
44
148
622
1.22
1.44
1.0
1.0
4.61
9.75
u/ml
1.46
17
79
77
516
1.30
1.43
1.1
1.0
10.18
9.73
u/ml
0.04
14
70
47
337
1.40
1.41
1.1
1.0
5.10
9.71
u/ml
—
6
43
171
878
1.19
1.39
1.0
1.1
4.96
10.80
u/ml
2.74
27
112
43
431
0.71
1.39
1.1
1.0
9.36
10.82
u/ml
—
6
58
24
127
1.61
1.37
1.1
1.1
7.19
5.40
u/ml
—
7
16
192
888
1.18
1.36
1.0
1.1
9.00
11.26
u/ml
0.37
26
118
137
856
1.21
1.33
1.1
1.1
9.31
9.22
u/ml
0.01
19
123
114
929
1.22
1.33
1.0
1.0
8.49
10.03
u/ml
0.27
18
120
124
519
1.22
1.30
1.1
1.0
4.62
10.42
u/ml
1.71
13
71
39
275
1.42
1.30
1.0
1.1
11.10
10.07
u/ml
—
6
37
60
686
0.76
1.28
1.1
1.0
2.71
10.96
u/ml
—
9
78
73
677
0.78
1.27
1.1
1.1
13.16
9.99
u/ml
0.20
12
94
92
740
1.24
1.25
1.0
1.0
6.48
9.69
u/ml
0.77
15
95
92
740
1.24
1.25
1.0
1.0
6.48
9.69
u/ml
0.77
15
95
18
107
1.69
1.25
1.0
1.0
11.40
5.39
u/ml
—
5
13
52
591
0.75
1.25
1.1
1.0
11.66
10.55
u/ml
—
7
81
87
695
1.25
1.25
1.1
1.0
12.25
9.71
u/ml
0.24
12
86
5
118
0.42
1.24
1.2
1.1
—
5.24
—
0
17
171
744
1.18
1.24
1.1
1.0
5.57
12.07
u/ml
2.12
27
97
135
1067
1.19
1.23
1.0
1.0
11.20
10.16
u/ml
0.10
22
144
100
689
0.81
1.22
1.0
1.1
3.20
9.81
u/ml
4.25
13
103
54
365
1.33
1.22
1.1
1.0
7.21
7.50
u/ml
—
7
41
81
320
1.27
1.21
1.0
1.1
4.36
10.95
u/ml
—
8
37
42
348
0.73
1.21
1.0
1.0
3.96
11.54
u/ml
—
8
39
51
626
0.76
1.20
1.0
1.0
8.16
10.26
u/ml
—
10
84
165
847
1.18
1.20
1.0
1.1
5.35
10.63
u/ml
1.72
24
120
65
359
1.30
1.19
1.1
1.0
12.23
11.06
u/ml
—
8
46
230
1016
1.15
1.19
1.0
1.0
11.71
10.77
u/ml
0.11
25
143
26
341
0.68
1.18
1.1
1.0
4.19
9.38
u/ml
—
7
44
27
181
1.49
1.17
1.0
1.0
2.14
16.45
u/ml
—
7
14
21
133
1.58
1.17
1.1
1.0
5.17
10.30
u/ml
—
5
17
10
50
2.01
1.16
1.0
1.0
—
5.93
—
0
7
67
512
1.28
1.16
1.1
1.0
8.80
10.13
u/ml
0.14
14
70
0
33
0.00
1.16
0.0
1.0
—
4.12
—
0
5
0
33
0.00
1.16
0.0
1.1
—
4.77
—
0
5
0
35
0.00
1.15
0.0
1.0
—
5.93
—
0
7
65
603
0.78
1.15
1.0
1.1
15.21
9.68
u/ml
0.36
12
79
25
166
1.51
1.14
1.0
1.1
21.95
4.72
u/ml
—
5
21
35
249
1.41
1.14
1.1
1.1
8.70
5.86
u/ml
—
6
30
0
36
0.00
1.14
0.0
1.0
—
5.93
—
0
7
77
420
1.25
1.11
1.1
1.0
11.62
10.95
u/ml
0.03
12
59
84
388
1.25
1.11
1.1
1.0
6.54
12.01
u/ml
—
9
55
84
388
1.25
1.11
1.1
1.0
6.54
12.01
u/ml
—
9
55
52
397
1.31
1.10
1.0
1.0
16.64
10.51
u/ml
—
5
47
120
874
0.84
1.10
1.1
1.1
10.87
9.92
u/ml
0.08
19
121
40
251
1.37
1.09
1.1
1.0
9.41
9.05
u/ml
—
5
35
12
66
1.82
1.09
1.2
1.0
—
6.22
—
0
9
48
356
1.32
1.09
1.0
1.1
20.56
8.73
u/ml
—
5
50
28
193
1.45
1.09
1.0
1.0
5.80
7.74
u/ml
—
5
27
85
394
1.24
1.08
1.1
1.0
6.54
12.01
u/ml
—
9
55
30
422
0.71
1.08
1.1
1.0
22.12
9.38
u/ml
—
5
51
96
855
0.83
1.07
1.0
1.1
11.13
9.86
u/ml
0.18
19
115
37
238
1.38
1.07
1.1
1.0
11.48
9.68
u/ml
—
8
29
74
585
1.25
1.07
1.0
1.0
7.93
12.19
u/ml
0.61
13
76
96
855
0.83
1.06
1.0
1.1
11.13
9.86
u/ml
0.18
19
115
17
106
1.61
1.02
1.1
1.1
—
5.70
—
0
18
42
315
1.34
1.02
1.0
1.0
8.20
7.24
u/ml
—
5
44
52
614
0.78
1.01
1.1
1.1
11.66
10.67
u/ml
—
7
85
37
271
1.36
1.01
1.0
1.0
10.42
9.46
u/ml
—
6
32
5
109
0.46
1.00
1.0
1.0
—
6.32
—
0
14
148
636
1.17
0.99
1.1
1.0
6.24
9.07
u/ml
0.62
17
84
241
1072
1.13
0.98
1.0
1.0
9.09
10.57
u/ml
0.25
28
145
96
850
0.84
0.98
1.0
1.1
11.13
10.00
u/ml
0.15
19
112
5
23
2.18
0.98
1.0
1.0
—
3.59
—
0
6
128
782
1.17
0.98
1.1
1.0
7.98
10.39
u/ml
0.29
18
106
115
727
1.18
0.97
1.1
1.0
13.17
13.01
u/ml
0.01
11
87
0
30
0.00
0.97
0.0
1.0
—
4.22
—
0
5
119
854
0.85
0.97
1.1
1.1
10.87
9.06
u/ml
0.17
19
119
103
479
1.20
0.96
1.1
1.0
6.06
10.49
u/ml
0.59
18
60
138
1084
1.16
0.96
1.0
1.0
11.19
10.01
u/ml
0.11
22
148
66
434
0.80
0.95
1.1
1.0
2.55
12.79
u/ml
—
8
46
0
32
0.00
0.95
0.0
1.0
—
4.12
—
0
5
20
294
0.68
0.94
1.1
1.0
2.45
9.69
u/ml
—
5
31
16
85
1.60
0.94
1.2
1.1
8.14
5.24
u/ml
—
5
10
43
187
1.33
0.94
1.1
1.1
10.97
9.34
u/ml
—
7
25
6
118
0.51
0.93
1.0
1.1
—
3.64
—
0
16
96
778
1.19
0.93
1.1
1.0
14.71
12.03
u/ml
—
5
100
137
1082
1.16
0.93
1.0
1.0
11.20
10.08
u/ml
0.11
22
147
48
349
1.29
0.92
1.1
1.0
11.46
9.44
u/ml
—
10
44
161
988
0.87
0.92
1.0
1.1
11.43
10.80
u/ml
0.06
16
143
9
52
1.73
0.92
1.0
1.1
—
4.02
—
0
7
232
1056
1.12
0.92
1.0
1.0
11.40
10.76
u/ml
0.07
23
149
60
479
1.25
0.91
1.0
1.0
6.01
10.53
u/ml
—
8
62
40
299
1.32
0.91
1.0
1.0
6.74
11.04
u/ml
—
7
41
90
698
1.20
0.90
1.1
1.1
5.54
8.53
u/ml
—
5
106
59
473
1.25
0.90
1.1
1.1
6.42
9.57
u/ml
0.41
12
52
67
464
0.81
0.90
1.0
1.1
10.89
7.97
u/ml
0.22
14
73
5
102
0.49
0.89
1.2
1.1
—
4.93
—
0
15
28
167
1.39
0.89
1.1
1.0
8.41
7.99
u/ml
—
6
18
5
103
0.48
0.89
1.2
1.0
—
5.09
—
0
14
62
501
1.24
0.89
1.1
1.1
4.21
10.60
u/ml
2.03
12
68
79
403
1.21
0.87
1.0
1.0
5.03
10.65
u/ml
1.49
14
53
6
30
2.00
0.87
1.0
1.1
—
1.96
—
0
7
83
694
1.20
0.86
1.0
1.0
6.37
10.96
u/ml
1.14
17
89
37
281
1.32
0.86
1.1
1.0
14.80
11.19
u/ml
—
5
30
63
768
0.82
0.85
1.0
1.1
20.63
9.07
u/ml
—
7
103
6
31
1.94
0.84
1.2
1.0
—
4.06
—
0
7
90
827
0.85
0.84
1.0
1.1
11.30
10.18
u/ml
0.14
18
108
146
996
0.88
0.84
1.0
1.0
14.95
9.68
u/ml
0.52
23
139
42
323
1.29
0.84
1.0
1.0
4.37
15.38
u/ml
—
8
36
51
335
0.80
0.83
1.0
1.0
4.31
14.26
u/ml
—
7
36
208
1212
1.12
0.83
1.1
1.0
9.27
11.23
u/ml
0.29
22
172
92
619
1.18
0.82
1.1
1.1
9.95
10.29
u/ml
0.02
15
89
23
163
1.41
0.81
1.2
1.0
6.83
4.91
u/ml
—
5
19
12
73
1.65
0.81
1.2
1.0
18.63
5.44
u/ml
—
5
10
123
533
1.16
0.79
1.0
1.0
6.71
9.16
u/ml
0.51
14
70
58
418
1.23
0.79
1.0
1.0
13.83
8.90
u/ml
—
6
51
31
233
1.33
0.79
1.1
1.0
—
7.86
—
0
29
149
1008
0.88
0.79
1.0
1.0
14.95
9.63
u/ml
0.53
23
141
0
26
0.00
0.78
0.0
1.0
—
3.23
—
0
7
66
425
0.83
0.78
1.1
1.0
3.13
13.07
u/ml
—
8
45
0
27
0.00
0.77
0.0
1.0
—
4.06
—
0
7
26
191
1.36
0.76
1.1
1.0
13.67
5.59
u/ml
—
8
21
26
191
1.36
0.76
1.0
1.0
6.96
19.29
u/ml
—
6
18
144
991
0.88
0.76
1.0
1.0
11.86
9.95
u/ml
0.19
22
137
77
520
0.84
0.76
1.0
1.1
11.24
8.14
u/ml
0.26
15
74
10
59
1.70
0.75
1.0
1.1
—
2.81
—
0
7
54
456
0.82
0.75
1.1
1.0
9.98
10.40
u/ml
0.03
12
56
53
418
1.23
0.75
1.1
1.0
22.49
9.06
u/ml
—
9
57
5
24
2.09
0.74
1.0
1.0
—
3.59
—
0
6
108
705
0.87
0.74
1.0
1.1
12.19
9.04
u/ml
0.37
19
100
17
116
1.47
0.74
1.1
1.1
14.48
5.17
u/ml
—
6
13
70
322
1.20
0.74
1.1
1.0
8.24
9.16
u/ml
0.09
18
43
85
664
0.85
0.74
1.0
1.0
9.14
10.01
u/ml
0.08
11
86
37
285
1.28
0.73
1.0
1.0
18.86
8.29
u/ml
—
8
35
108
704
0.87
0.73
1.0
1.1
12.19
9.04
u/ml
0.37
19
100
131
762
1.14
0.71
1.0
1.0
8.11
8.09
u/ml
0.00
14
104
54
442
1.22
0.71
1.1
1.0
16.24
10.14
u/ml
—
9
55
31
238
1.30
0.70
1.1
1.1
2.24
6.98
u/ml
—
8
28
50
408
1.23
0.70
1.1
1.0
11.97
7.46
u/ml
—
6
51
148
1160
1.12
0.69
1.1
1.0
10.91
10.53
u/ml
0.04
21
161
32
294
0.78
0.69
1.1
1.1
6.63
7.40
u/ml
—
5
39
41
329
1.25
0.67
1.1
1.0
12.04
7.00
u/ml
—
5
46
35
266
1.27
0.67
1.0
1.0
8.31
7.96
u/ml
—
9
33
54
647
0.83
0.66
1.1
1.0
6.99
8.73
u/ml
—
10
89
93
566
1.16
0.66
1.1
1.0
8.93
13.80
u/ml
0.53
17
66
50
411
1.22
0.66
1.0
1.1
9.23
7.37
u/ml
—
5
58
5
95
0.53
0.66
1.0
1.1
—
4.57
—
0
11
123
985
1.13
0.65
1.1
1.0
11.73
11.42
u/ml
0.02
18
121
106
657
1.14
0.65
1.1
1.0
3.77
9.58
u/ml
2.31
16
98
27
206
1.31
0.65
1.1
1.0
26.20
9.52
u/ml
—
5
28
53
442
1.20
0.62
1.0
1.0
7.17
9.31
u/ml
—
8
56
10
63
1.59
0.62
1.1
1.0
—
5.21
—
0
11
61
257
1.19
0.61
1.0
1.0
6.32
11.94
u/ml
—
6
33
30
235
1.28
0.61
1.0
1.1
4.02
12.27
u/ml
—
5
35
60
378
0.84
0.61
1.1
1.0
2.70
14.26
u/ml
—
7
40
198
1188
1.10
0.60
1.1
1.0
9.12
11.28
u/ml
0.41
35
157
34
270
1.25
0.60
1.1
1.0
4.37
17.67
u/ml
—
8
28
44
362
1.22
0.59
1.0
1.0
10.79
8.51
u/ml
—
5
46
12
80
1.50
0.59
1.0
1.0
—
6.27
—
0
7
0
23
0.00
0.58
0.0
1.0
—
4.12
—
0
5
56
467
1.18
0.58
1.1
1.0
4.15
9.41
u/ml
—
8
62
33
264
1.25
0.57
1.0
1.0
1.54
5.91
u/ml
—
5
37
71
603
1.16
0.57
1.0
1.0
6.74
9.44
u/ml
0.38
11
80
25
193
1.30
0.57
1.1
1.1
12.50
5.75
u/ml
—
7
23
5
87
0.57
0.56
1.0
1.1
—
5.00
—
0
12
26
306
0.79
0.56
1.1
1.0
—
12.12
—
0
33
5
90
0.55
0.55
1.0
1.0
—
4.83
—
0
14
130
1122
1.11
0.55
1.0
1.0
10.64
11.68
u/ml
0.15
23
145
200
1216
0.92
0.55
1.1
1.0
11.84
10.85
u/ml
0.11
31
162
15
107
1.40
0.55
1.1
1.0
—
4.73
—
0
14
8
122
0.65
0.54
1.0
1.0
—
5.18
—
0
14
6
38
1.58
0.54
1.0
1.0
—
3.56
—
0
8
6
38
1.58
0.54
1.0
1.0
—
6.44
—
0
5
40
330
1.21
0.54
1.1
1.0
5.65
11.49
u/ml
—
7
45
62
716
0.86
0.54
1.0
1.1
8.57
10.84
u/ml
0.36
13
90
48
557
0.84
0.53
1.1
1.0
11.66
10.86
u/ml
—
7
76
174
987
1.09
0.53
1.1
1.0
8.39
10.45
u/ml
0.27
22
133
22
169
1.30
0.53
1.0
1.1
23.31
10.01
u/ml
—
5
20
39
319
1.21
0.53
1.1
1.0
6.42
9.89
u/ml
—
7
42
35
263
1.23
0.52
1.1
1.0
9.00
6.37
u/ml
—
6
22
31
250
1.24
0.52
1.0
1.1
15.13
4.77
u/ml
—
7
31
45
310
0.84
0.52
1.1
1.0
6.11
11.69
u/ml
—
7
36
55
470
1.17
0.52
1.1
1.0
18.94
10.23
u/ml
—
10
60
14
100
1.40
0.51
1.0
1.0
—
7.81
—
0
13
9
136
0.66
0.51
1.0
1.0
—
10.54
—
0
13
62
446
1.16
0.51
1.0
1.1
18.39
8.31
u/ml
—
10
57
43
480
0.84
0.50
1.0
1.0
8.20
8.81
u/ml
—
6
63
188
952
1.09
0.49
1.1
1.0
9.07
11.48
u/ml
0.24
22
133
48
491
0.85
0.49
1.1
1.0
5.52
8.61
u/ml
—
10
68
58
496
1.16
0.48
1.0
1.1
8.21
13.64
u/ml
—
7
55
16
212
0.75
0.48
1.3
1.0
12.81
6.72
u/ml
—
5
26
7
108
0.65
0.48
1.0
1.0
—
3.69
—
0
16
20
154
1.30
0.48
1.1
1.1
9.30
9.45
u/ml
—
8
19
40
314
1.19
0.48
1.1
1.0
15.31
11.33
u/ml
—
10
40
7
46
1.52
0.48
1.0
1.1
—
3.25
—
0
6
103
832
0.90
0.48
1.0
1.1
14.79
9.79
u/ml
0.65
22
105
132
754
1.10
0.48
1.1
1.0
6.66
11.17
u/ml
1.00
25
104
42
371
0.84
0.47
1.0
1.0
8.00
10.20
u/ml
—
7
46
170
1028
0.92
0.47
1.1
1.0
14.26
10.76
u/ml
0.41
21
149
105
975
0.90
0.47
1.1
1.0
12.62
10.49
u/ml
0.17
13
129
207
1064
1.08
0.46
1.1
1.0
9.81
10.43
u/ml
0.06
23
156
173
1040
0.92
0.46
1.1
1.0
14.26
10.76
u/ml
0.41
21
149
89
738
1.12
0.46
1.0
1.0
16.73
9.86
u/ml
0.48
15
92
7
49
1.43
0.46
1.0
1.0
—
3.59
—
0
6
5
83
0.60
0.45
1.0
1.0
—
3.50
—
0
11
8
119
0.67
0.45
1.0
1.1
—
4.47
—
0
15
131
852
0.91
0.45
1.0
1.1
12.31
8.41
u/ml
0.44
21
120
8
120
0.67
0.45
1.1
1.0
—
3.73
—
0
13
5
84
0.59
0.45
1.0
1.1
—
4.05
—
0
13
37
310
1.19
0.45
1.0
1.1
18.86
7.84
u/ml
—
8
47
147
926
0.92
0.45
1.0
1.0
12.15
9.53
u/ml
0.30
21
131
5
85
0.59
0.45
1.0
1.0
—
4.07
—
0
11
89
578
0.89
0.45
1.0
1.1
13.01
8.28
u/ml
0.56
17
84
14
103
1.36
0.45
1.1
1.1
—
4.83
—
0
15
59
451
0.87
0.45
1.1
1.0
6.16
9.33
u/ml
0.56
14
67
114
699
0.91
0.43
1.1
1.0
5.08
10.60
u/ml
1.62
20
96
77
392
1.13
0.43
1.0
1.0
1.29
11.70
u/ml
—
6
52
14
104
1.35
0.43
1.1
1.1
—
5.12
—
0
14
5
31
1.62
0.43
1.0
1.0
—
4.22
—
0
5
40
456
0.85
0.43
1.0
1.1
6.18
9.67
u/ml
—
5
63
8
56
1.43
0.42
1.0
1.0
—
12.64
—
0
6
12
87
1.38
0.42
1.0
1.1
—
5.74
—
0
10
112
512
1.10
0.41
1.0
1.0
4.89
12.06
u/ml
1.95
13
64
99
548
1.11
0.41
1.0
1.1
19.78
10.95
u/ml
—
8
81
34
386
0.84
0.41
1.0
1.0
19.85
8.21
u/ml
—
6
50
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
121
958
1.09
0.41
1.0
1.1
7.60
10.33
u/ml
0.50
13
134
37
265
0.85
0.40
1.1
1.0
1.78
10.99
u/ml
—
7
31
65
385
1.13
0.40
1.0
1.0
4.91
10.90
u/ml
—
10
51
89
435
1.11
0.40
1.0
1.1
8.46
13.16
u/ml
0.54
12
57
36
422
0.85
0.40
1.1
1.1
4.60
9.23
u/ml
—
6
55
36
422
0.85
0.40
1.1
1.1
4.60
9.13
u/ml
—
6
56
12
88
1.36
0.40
1.1
1.1
—
4.26
—
0
12
98
888
1.10
0.39
1.1
1.0
13.46
10.14
u/ml
0.27
17
112
5
35
1.43
0.39
1.0
1.0
—
4.22
—
0
5
42
442
0.87
0.38
1.0
1.0
41.84
8.98
u/ml
—
6
52
50
438
1.14
0.38
1.0
1.1
9.23
9.11
u/ml
—
5
62
8
113
0.71
0.37
1.0
1.1
—
3.80
—
0
17
5
37
1.35
0.37
1.2
1.1
—
3.17
—
0
6
9
70
1.29
0.36
1.0
1.0
—
3.66
—
0
10
10
130
0.74
0.36
1.1
1.0
—
11.02
—
0
13
145
975
1.08
0.36
1.1
1.0
8.51
11.38
u/ml
0.64
27
127
50
403
1.14
0.35
1.1
1.0
9.94
11.42
u/ml
—
9
45
68
405
1.12
0.35
1.1
1.0
8.14
10.05
u/ml
—
6
54
29
244
1.19
0.35
1.0
1.1
23.99
9.00
u/ml
—
7
33
108
670
0.92
0.35
1.0
1.1
11.61
8.78
u/ml
0.33
20
93
19
224
0.81
0.35
1.1
1.0
—
10.78
—
0
20
59
527
1.12
0.35
1.1
1.1
6.42
8.19
u/ml
0.21
12
68
6
44
1.36
0.34
1.0
1.0
—
4.16
—
0
6
74
544
0.91
0.34
1.1
1.0
13.23
7.66
u/ml
0.56
11
77
154
742
1.07
0.33
1.0
1.0
6.85
12.07
u/ml
1.21
18
97
123
899
0.93
0.33
1.0
1.1
14.95
9.53
u/ml
0.39
17
127
12
91
1.32
0.33
1.1
1.1
—
4.26
—
0
12
122
847
0.93
0.33
1.1
1.1
5.20
10.14
u/ml
1.66
21
115
36
312
1.15
0.33
1.0
1.1
12.30
7.20
u/ml
—
7
41
48
425
1.13
0.33
1.0
1.0
23.61
9.59
u/ml
—
8
55
96
535
1.09
0.33
1.1
1.1
15.80
10.54
u/ml
0.28
11
75
6
89
0.67
0.33
1.0
1.1
—
3.92
—
0
14
41
464
0.88
0.31
1.0
1.1
7.62
8.67
u/ml
—
5
74
127
648
1.08
0.31
1.0
1.1
11.21
10.05
u/ml
0.08
20
91
76
750
0.91
0.31
1.1
1.0
4.01
9.20
u/ml
—
9
113
7
53
1.32
0.31
1.1
1.0
—
4.99
—
0
8
10
131
0.76
0.30
1.1
1.1
—
6.44
—
0
17
15
120
1.25
0.30
1.0
1.0
—
10.47
—
0
18
119
713
1.07
0.29
1.1
1.0
4.58
11.27
u/ml
1.69
19
102
14
174
0.80
0.29
1.1
1.0
10.83
5.24
u/ml
—
5
20
7
56
1.25
0.29
1.0
1.1
—
3.49
—
0
6
41
363
1.13
0.29
1.0
1.0
23.15
8.25
u/ml
—
6
44
8
109
0.73
0.29
1.0
1.0
—
5.83
—
0
17
126
704
0.94
0.28
1.1
1.0
7.85
10.34
u/ml
0.37
24
97
40
288
0.89
0.28
1.1
1.0
4.87
11.05
u/ml
—
8
35
203
1013
1.05
0.27
1.1
1.0
5.66
12.46
u/ml
2.81
34
142
27
233
1.16
0.27
1.1
1.1
8.65
6.67
u/ml
—
6
39
32
279
1.14
0.27
1.1
1.1
10.28
9.59
u/ml
—
6
38
5
73
0.68
0.26
1.0
1.0
—
4.07
—
0
11
5
73
0.68
0.26
1.0
1.0
—
7.40
—
0
7
60
391
0.91
0.26
1.0
1.0
15.79
9.60
u/ml
0.58
13
48
123
788
0.94
0.25
1.0
1.1
12.17
9.13
u/ml
0.32
21
110
9
73
1.23
0.25
1.0
1.1
—
6.21
—
0
9
77
542
0.93
0.25
1.0
1.1
13.03
9.83
u/ml
0.23
14
71
32
361
0.89
0.24
1.1
1.1
5.90
7.53
u/ml
—
6
46
9
77
1.17
0.24
1.1
1.0
—
6.37
—
0
11
151
919
0.95
0.24
1.0
1.0
13.43
9.84
u/ml
0.45
20
129
6
81
0.74
0.24
1.0
1.0
—
7.89
—
0
11
63
430
1.09
0.24
1.0
1.0
15.98
11.56
u/ml
—
10
60
22
189
1.16
0.24
1.0
1.0
13.65
8.59
u/ml
—
6
31
49
446
1.10
0.23
1.1
1.0
18.51
8.40
u/ml
—
10
57
65
566
0.92
0.23
1.1
1.0
19.00
9.48
u/ml
—
7
82
197
1051
1.05
0.23
1.0
1.0
13.14
10.28
u/ml
0.36
26
145
26
296
0.88
0.23
1.1
1.1
6.81
6.58
u/ml
—
6
44
51
360
1.10
0.23
1.0
1.1
12.67
8.91
u/ml
—
6
46
12
97
1.24
0.22
1.0
1.0
12.90
7.70
u/ml
—
5
9
98
505
1.07
0.22
1.0
1.1
8.32
10.59
u/ml
—
9
75
5
40
1.25
0.22
1.0
1.0
—
4.92
—
0
5
7
95
0.74
0.22
1.0
1.1
—
4.47
—
0
13
98
875
1.06
0.22
1.1
1.1
6.37
10.31
u/ml
0.67
11
123
5
41
1.22
0.22
1.0
1.1
—
4.77
—
0
5
55
336
1.09
0.21
1.0
1.0
7.34
9.97
u/ml
—
8
47
5
42
1.19
0.21
1.0
1.0
—
6.75
—
0
6
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
16
135
1.19
0.21
1.1
1.1
—
7.51
—
0
19
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
31
345
0.90
0.21
1.0
1.0
11.78
11.30
u/ml
—
5
40
5
43
1.16
0.21
1.0
1.0
—
4.76
—
0
6
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
84
739
1.06
0.20
1.1
1.0
6.95
10.79
u/ml
0.43
14
89
25
209
1.13
0.20
1.1
1.0
5.22
10.37
u/ml
—
5
30
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
61
565
1.08
0.20
1.1
1.0
14.07
9.42
u/ml
—
7
71
6
48
1.25
0.20
1.0
1.0
—
3.22
—
0
6
19
211
0.87
0.20
1.2
1.1
12.90
7.44
u/ml
—
7
27
6
49
1.22
0.20
1.0
1.1
—
3.70
—
0
7
49
383
0.92
0.20
1.1
1.0
6.62
15.43
u/ml
—
5
42
15
176
0.85
0.19
1.0
1.0
10.63
3.59
u/ml
—
5
18
198
1075
0.96
0.19
1.1
1.0
9.93
11.05
u/ml
0.10
22
143
10
121
0.82
0.19
1.1
1.0
—
7.72
—
0
14
38
300
1.10
0.19
1.1
1.0
7.35
10.87
u/ml
—
6
42
6
52
1.15
0.19
1.0
1.0
—
6.53
—
0
7
6
52
1.15
0.19
1.0
1.1
—
5.76
—
0
10
198
1073
0.96
0.18
1.1
1.0
9.93
11.05
u/ml
0.10
22
143
28
251
1.12
0.18
1.1
1.1
5.17
9.20
u/ml
—
5
31
166
978
0.96
0.18
1.0
1.1
14.61
10.14
u/ml
0.57
23
141
21
238
0.88
0.18
1.0
1.1
10.86
7.46
u/ml
—
5
31
67
529
1.07
0.18
1.0
1.0
15.10
11.44
u/ml
—
6
61
24
213
1.13
0.18
1.1
1.0
15.18
5.42
u/ml
—
5
24
39
357
1.09
0.18
1.0
1.1
11.86
11.54
u/ml
—
9
47
12
100
1.20
0.18
1.0
1.1
—
3.33
—
0
12
7
60
1.17
0.18
1.1
1.0
—
6.64
—
0
8
73
440
1.06
0.18
1.1
1.0
4.58
10.54
u/ml
1.45
11
54
7
60
1.17
0.17
1.0
1.0
—
6.01
—
0
8
21
237
0.89
0.17
1.0
1.1
10.86
7.46
u/ml
—
5
31
61
571
1.07
0.17
1.0
1.0
6.92
9.54
u/ml
0.31
11
77
100
747
1.05
0.17
1.1
1.0
12.78
8.08
u/ml
0.74
18
104
50
432
0.93
0.17
1.0
1.1
9.81
8.68
u/ml
—
10
55
14
163
0.86
0.17
1.1
1.0
—
7.57
—
0
28
41
401
0.92
0.17
1.0
1.0
12.95
7.98
u/ml
—
5
47
30
262
1.10
0.17
1.1
1.0
5.90
8.06
u/ml
—
6
32
30
294
0.91
0.17
1.0
1.0
18.17
7.44
u/ml
—
6
34
5
67
0.75
0.17
1.2
1.0
—
3.34
—
0
9
5
61
0.71
0.17
1.0
1.0
—
7.10
—
0
7
5
68
0.73
0.17
1.2
1.0
—
3.57
—
0
10
5
70
0.71
0.16
1.0
1.0
—
7.89
—
0
11
41
256
1.09
0.16
1.0
1.1
7.35
10.72
u/ml
—
6
33
8
68
1.18
0.16
1.1
1.0
—
5.34
—
0
8
29
319
0.91
0.16
1.0
1.0
10.65
7.79
u/ml
—
6
41
8
70
1.14
0.16
1.1
1.0
—
5.78
—
0
11
14
120
1.17
0.16
1.1
1.1
—
7.40
—
0
17
217
1203
1.03
0.16
1.0
1.0
13.36
10.62
u/ml
0.33
33
160
14
162
0.86
0.16
1.0
1.1
18.18
8.51
u/ml
—
5
21
8
71
1.13
0.16
1.0
1.1
—
3.22
—
0
12
62
440
1.06
0.16
1.0
1.1
3.54
7.93
u/ml
—
5
58
55
583
0.94
0.16
1.1
1.0
11.76
8.82
u/ml
—
6
83
6
75
0.78
0.15
1.0
1.0
—
7.46
—
0
7
51
355
1.07
0.15
1.1
1.0
7.85
9.54
u/ml
—
8
46
6
78
0.77
0.15
1.0
1.1
—
5.06
—
0
8
13
86
1.17
0.15
1.1
1.1
12.80
9.77
u/ml
—
5
9
33
302
1.09
0.15
1.1
1.0
15.82
8.06
u/ml
—
6
36
170
1138
1.03
0.15
1.1
1.0
8.46
10.84
u/ml
0.55
28
150
9
64
1.11
0.15
1.0
1.1
—
4.17
—
0
7
37
249
1.08
0.15
1.0
1.0
15.59
11.98
u/ml
—
5
29
33
358
0.92
0.14
1.0
1.1
10.65
9.58
u/ml
—
6
48
7
88
0.79
0.14
1.0
1.1
—
4.90
—
0
12
112
1000
1.04
0.14
1.1
1.0
10.44
10.68
u/ml
0.02
16
124
16
141
1.14
0.13
1.0
1.1
24.60
8.68
u/ml
—
5
21
12
103
1.17
0.13
1.0
1.1
—
3.13
—
0
13
8
98
0.82
0.13
1.0
1.1
—
5.23
—
0
14
88
835
1.05
0.13
1.0
1.0
7.75
11.30
u/ml
—
10
101
49
461
1.06
0.13
1.0
1.0
8.13
8.28
u/ml
—
9
61
106
755
0.96
0.13
1.1
1.1
5.57
10.33
u/ml
1.31
19
104
23
252
0.91
0.12
1.0
1.1
10.42
7.36
u/ml
—
6
33
23
252
0.91
0.12
1.0
1.1
10.42
7.36
u/ml
—
6
33
77
425
1.05
0.12
1.0
1.0
5.43
9.88
u/ml
1.01
13
53
12
104
1.15
0.12
1.1
1.0
—
6.20
—
0
11
18
165
0.90
0.12
1.0
1.1
11.75
10.61
u/ml
—
6
19
29
259
1.08
0.12
1.1
1.0
6.82
8.06
u/ml
—
5
32
28
218
0.92
0.11
1.0
1.1
19.64
9.49
u/ml
—
5
29
171
1148
1.03
0.11
1.1
1.0
8.46
10.73
u/ml
0.51
28
152
79
758
1.04
0.11
1.1
1.0
9.46
10.23
u/ml
0.07
14
91
115
754
1.03
0.11
1.0
1.0
8.01
12.81
u/ml
0.49
14
92
12
105
1.14
0.11
1.0
1.1
—
3.26
—
0
15
12
105
1.14
0.11
1.0
1.0
—
5.05
—
0
13
52
494
1.05
0.11
1.1
1.0
7.08
8.87
u/ml
—
7
75
12
136
0.88
0.11
1.2
1.1
—
4.93
—
0
19
10
82
1.16
0.11
1.1
1.0
—
9.53
—
0
7
120
763
0.97
0.11
1.0
1.1
12.17
9.25
u/ml
0.30
21
102
86
487
1.04
0.10
1.0
1.1
1.23
11.02
u/ml
—
7
71
198
1053
0.98
0.10
1.1
1.0
9.11
11.22
u/ml
0.20
22
139
51
485
1.05
0.10
1.1
1.0
12.40
9.28
u/ml
—
6
63
198
1053
0.98
0.10
1.1
1.0
9.11
11.22
u/ml
0.20
22
139
86
521
1.04
0.10
1.0
1.1
1.16
10.68
u/ml
—
8
72
51
534
0.95
0.10
1.1
1.1
13.92
8.78
u/ml
—
5
81
11
94
1.15
0.10
1.0
1.0
—
5.35
—
0
12
198
1052
0.98
0.10
1.1
1.0
9.11
11.26
u/ml
0.21
22
138
88
660
1.04
0.10
1.0
1.1
18.14
8.75
u/ml
1.20
17
84
5
44
1.14
0.10
1.0
1.0
—
4.84
—
0
9
27
243
1.07
0.10
1.1
1.0
9.04
11.55
u/ml
—
5
29
5
45
1.11
0.09
1.2
1.0
—
5.14
—
0
8
5
46
1.09
0.09
1.0
1.0
—
6.70
—
0
7
5
46
1.09
0.09
1.0
1.1
—
3.47
—
0
8
56
404
0.96
0.09
1.1
1.0
8.88
8.90
u/ml
—
7
50
5
47
1.06
0.09
1.0
1.1
—
3.71
—
0
5
39
358
1.06
0.09
1.1
1.0
4.09
9.57
u/ml
—
9
39
126
773
0.97
0.09
1.0
1.1
12.44
9.17
u/ml
0.32
20
108
75
738
0.96
0.09
1.1
1.0
11.59
11.45
u/ml
0.01
11
83
41
376
1.05
0.09
1.0
1.1
2.80
13.53
u/ml
—
5
54
40
333
1.05
0.09
1.0
1.0
7.51
10.54
u/ml
—
6
49
25
233
1.07
0.09
1.0
1.0
22.78
6.81
u/ml
—
5
25
6
54
1.11
0.09
1.2
1.0
—
4.58
—
0
6
41
384
0.95
0.08
1.1
1.0
8.88
9.27
u/ml
—
10
54
27
208
0.94
0.08
1.0
1.1
19.64
10.22
u/ml
—
5
25
6
56
1.07
0.08
1.0
1.1
—
3.13
—
0
7
6
57
1.05
0.08
1.0
1.0
—
4.76
—
0
9
6
57
1.05
0.08
1.0
1.0
—
4.53
—
0
10
19
175
1.09
0.08
1.2
1.1
7.49
6.69
u/ml
—
5
29
126
771
0.97
0.08
1.0
1.1
12.44
8.48
u/ml
0.42
20
107
13
144
0.90
0.08
1.0
1.0
—
7.03
—
0
15
5
61
0.82
0.08
1.0
1.0
—
4.07
—
0
11
23
226
0.93
0.08
1.0
1.0
18.17
7.15
u/ml
—
6
28
5
65
0.77
0.08
1.0
1.0
—
3.10
—
0
11
5
65
0.77
0.08
1.0
1.1
—
5.06
—
0
8
44
416
1.05
0.08
1.0
1.0
17.06
8.31
u/ml
—
7
47
32
338
0.95
0.08
1.0
1.1
7.83
7.89
u/ml
—
5
42
7
67
1.04
0.08
1.0
1.0
—
4.39
—
0
10
17
182
0.92
0.07
1.1
1.0
18.65
6.48
u/ml
—
5
23
48
285
1.04
0.07
1.0
1.1
13.47
6.00
u/ml
—
6
37
6
70
0.85
0.07
1.0
1.0
—
7.09
—
0
7
6
71
0.84
0.07
1.0
1.1
—
8.24
—
0
9
37
257
1.05
0.07
1.0
1.0
15.59
11.98
u/ml
—
5
29
28
214
0.94
0.07
1.0
1.1
19.64
9.49
u/ml
—
5
29
8
74
1.08
0.07
1.1
1.1
—
3.09
—
0
12
73
753
0.97
0.07
1.1
1.1
19.70
9.09
u/ml
0.82
13
97
91
574
1.03
0.07
1.1
1.0
4.01
9.82
u/ml
1.85
14
79
8
78
1.03
0.07
1.0
1.0
—
4.07
—
0
11
25
235
1.06
0.07
1.0
1.0
16.82
4.57
u/ml
—
5
29
141
1032
0.98
0.07
1.1
1.0
8.77
10.58
u/ml
0.24
17
143
14
124
1.10
0.07
1.0
1.1
—
5.38
—
0
16
39
365
1.05
0.07
1.1
1.1
9.99
9.10
u/ml
—
7
47
46
442
1.04
0.07
1.0
1.0
10.14
10.80
u/ml
—
8
49
8
89
0.88
0.06
1.1
1.0
—
9.87
—
0
7
8
95
0.84
0.06
1.0
1.1
—
4.15
—
0
10
104
746
0.98
0.06
1.1
1.1
5.57
9.63
u/ml
1.11
19
101
123
682
0.98
0.06
1.1
1.0
8.27
9.16
u/ml
0.10
21
92
17
159
1.07
0.05
1.0
1.0
—
6.74
—
0
25
12
110
1.09
0.05
1.0
1.1
—
3.13
—
0
15
68
447
1.03
0.05
1.0
1.0
7.38
9.53
u/ml
—
9
60
84
727
1.02
0.05
1.1
1.1
5.73
9.52
u/ml
0.87
15
102
20
211
0.95
0.04
1.0
1.0
16.82
6.55
u/ml
—
5
26
95
616
1.02
0.04
1.1
1.1
8.53
8.77
u/ml
—
10
83
10
91
1.10
0.04
1.0
1.0
—
4.92
—
0
13
90
601
1.02
0.04
1.1
1.0
6.49
8.33
u/ml
0.30
16
87
39
378
1.03
0.04
1.1
1.1
14.04
10.00
u/ml
—
5
51
39
378
1.03
0.04
1.1
1.1
14.04
10.17
u/ml
—
5
50
80
512
0.98
0.03
1.1
1.0
5.88
10.36
u/ml
0.96
12
60
13
121
1.07
0.03
1.2
1.0
—
7.46
—
0
19
44
449
0.97
0.03
1.1
1.0
13.11
10.23
u/ml
—
6
56
13
139
0.94
0.03
1.1
1.1
—
4.67
—
0
18
131
785
0.99
0.03
1.0
1.1
12.44
9.27
u/ml
0.31
20
113
94
620
0.98
0.03
1.1
1.0
5.17
10.03
u/ml
1.41
12
96
61
568
1.02
0.03
1.1
1.1
4.38
10.63
u/ml
—
8
79
11
102
1.08
0.03
1.0
1.1
—
4.60
—
0
16
19
187
0.96
0.02
1.1
1.0
—
14.75
—
0
20
61
378
1.02
0.02
1.0
1.1
22.19
6.36
u/ml
1.13
12
45
36
351
1.03
0.02
1.1
1.0
14.80
10.30
u/ml
—
5
46
31
286
1.03
0.02
1.1
1.0
5.90
9.55
u/ml
—
6
36
14
132
1.06
0.02
1.1
1.1
—
7.86
—
0
18
76
705
0.99
0.02
1.0
1.1
8.89
9.81
u/ml
—
8
93
11
103
1.07
0.02
1.0
1.1
—
4.52
—
0
17
29
298
0.97
0.02
1.0
1.1
3.58
10.74
u/ml
—
5
35
11
100
1.06
0.01
1.0
1.0
—
5.35
—
0
12
99
653
1.01
0.01
1.1
1.1
11.26
10.69
u/ml
0.03
14
85
16
154
1.04
0.00
1.1
1.0
—
5.69
—
0
19
14
81
0.96
0.00
1.1
1.0
—
6.81
—
0
8
29
229
0.98
0.00
1.0
1.1
26.50
5.82
u/ml
—
8
28
77
742
1.00
0.00
1.0
1.0
3.21
11.69
u/ml
—
6
71
35
289
1.00
0.00
1.1
1.1
4.17
9.30
u/ml
—
5
36
15
143
0.97
0.00
1.0
1.0
—
7.86
—
0
23
54
511
1.01
0.00
1.1
1.0
8.18
8.55
u/ml
—
10
66
42
301
1.01
0.00
1.0
1.1
7.35
10.81
u/ml
—
6
41
165
901
1.00
0.00
1.0
1.0
8.34
12.46
u/ml
0.74
22
119
16
156
1.03
0.00
1.1
1.0
—
6.27
—
0
25
45
384
1.00
0.00
1.1
1.0
22.74
10.89
u/ml
—
5
56
34
336
1.01
0.00
1.0
1.1
21.65
6.67
u/ml
—
9
51
53
525
1.01
0.00
1.1
1.0
6.42
8.62
u/ml
—
5
81
22
225
0.98
0.00
1.1
1.0
—
7.65
—
0
26
39
379
1.00
0.00
1.1
1.1
9.99
9.10
u/ml
—
7
47
29
291
1.00
0.00
1.0
1.1
10.65
7.78
u/ml
—
6
36
42
312
0.99
0.00
1.0
1.1
7.54
13.89
u/ml
—
6
39
13
133
0.98
0.00
1.1
1.0
—
5.23
—
0
18
20
199
1.01
0.00
1.0
1.0
16.82
4.53
u/ml
—
5
26
178
1012
1.00
0.00
1.1
1.0
9.98
10.27
u/ml
0.03
18
144
6
59
0.91
0.00
1.0
1.1
—
5.40
—
0
7
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.0
1.1
—
9.98
—
0
9
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
22
220
1.00
0.00
1.0
1.1
—
8.68
—
0
35
6
69
0.86
0.00
1.0
1.0
—
6.77
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
5
0.00
0.00
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—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
5
0.00
0.00
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—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
5.23
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
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—
—
—
0
0
0
9
0.00
0.00
0.0
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—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
6
0.00
0.00
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—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
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1.0
—
—
—
0
0
0
5
0.00
0.00
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—
—
—
0
0
0
8
0.00
0.00
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1.0
—
—
—
0
0
0
6
0.00
0.00
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1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
89
1.01
0.00
1.1
1.1
—
5.87
—
0
12
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.92
0.00
1.0
1.0
—
6.81
—
0
9
17
170
1.00
0.00
1.1
1.0
—
6.13
—
0
21
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.0
1.0
—
3.95
—
0
11
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
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1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
0.00
1.0
1.1
—
3.59
—
0
10
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.0
1.0
—
6.25
—
0
10
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.0
1.0
—
4.63
—
0
7
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
3.60
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
73
0.99
0.00
1.0
1.1
—
7.15
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
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—
—
—
0
0
0
5
0.00
0.00
0.0
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—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
1.0
1.0
—
3.84
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
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1.0
—
—
—
0
0
0
9
0.00
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0.0
1.0
—
—
—
0
0