Impetigo

L12_IMPETIGO

impetigo: A pyoderma consisting of three forms of skin lesions having either a thick, adherent, recurrent, dirty yellow crust with an erythematous margin (common or superficial impetigo) or lessions which are superficial, thin-walled, and bullous as found in bullous impetigo. The lesions in bullous (staphylococcal) impetigo, which are always caused by S aureus, are superficial, thin-walled, and bullous.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L01
  • Hospital discharge: ICD-9 684
  • Hospital discharge: ICD-8 684|70708
  • Cause of death: ICD-10 L01
  • Cause of death: ICD-9 684
  • Cause of death: ICD-8 684|70708

2 out of 7 registries used, show all original rules.

2201

4. Check minimum number of events

None

2201

5. Include endpoints

None

2201

6. Filter based on genotype QC (FinnGen only)

1968

Control definitions (FinnGen only)

Control exclude
L12_INFECT_SKIN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L00-L08
Name in latin
Impetigo

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 28301 13366 14843
Only index persons 20231 9754 10477
Unadjusted period prevalence (%)
Whole population 0.40 0.38 0.41
Only index persons 0.38 0.36 0.40
Median age at first event (years)
Whole population 10.66 11.12 10.05
Only index persons 15.69 15.96 15.43

-FinnGen-

Key figures

All Female Male
Number of individuals 1968 1167 801
Unadjusted period prevalence (%) 0.40 0.41 0.37
Median age at first event (years) 26.91 28.00 25.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2036
Matched controls
20356
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
151.9
307.7
393
32
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
103.9
307.7
988
183
L01
ICD-10 Finland
Impetigo
12.7
215.0
218
190
68409
ICD-8 Finland
Impetigo, Unspecified
+∞
212.3
200
*
68408
ICD-8 Finland
Impetigo, Alia definita
+∞
195.0
184
*
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
16.0
154.9
135
90
L20.0
ICD-10 Finland
Besnier prurigo
4.1
142.5
468
1367
6840A
ICD-9 Finland
Impetigo[IMPETIGO CONTAGIOSA]
+∞
131.7
125
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.6
113.6
466
1565
E0000UV, ,
ATC
2.7
107.5
1142
6461
D07BA04
ATC
hydrocortisone and antiseptics; topical
3.4
94.2
409
1411
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.7
86.8
617
2792
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
7.2
85.4
131
193
D07AC01
ATC
betamethasone; topical
2.5
82.8
865
4686
D07AB08
ATC
desonide; topical
3.3
81.7
360
1246
D07AA02
ATC
hydrocortisone; topical
2.8
80.6
501
2105
TQW80
NOMESCO Finland
Local dermatologic skincare
7.3
75.4
114
165
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
7.3
74.1
112
162
L30.3
ICD-10 Finland
Infective dermatitis
5.4
70.0
145
287
E000001, ,
ATC
2.5
69.8
566
2692
J01FF01
ATC
clindamycin; systemic
2.5
68.2
598
2943
L08.0
ICD-10 Finland
Pyoderma
14.2
67.5
62
45
A46
ICD-10 Finland
Erysipelas
3.1
66.9
314
1121
D11AH01
ATC
tacrolimus; topical
8.3
64.7
86
107
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
10.1
64.5
74
76
E000002, ,
ATC
2.8
62.6
358
1423
J01DB01
ATC
cefalexin; oral
2.9
59.4
1765
14129
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.9
59.2
186
512
D07CC01
ATC
betamethasone and antibiotics; topical
2.7
51.0
319
1319
XQ802
NOMESCO Finland
Epicutan test
4.0
50.4
148
387
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
50.2
683
3948
D11AH02
ATC
pimecrolimus; topical
12.2
49.8
50
42
D11AX14
ATC
[U] tacrolimus
15.0
49.4
44
30
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
48.9
212
717
D07AC13
ATC
mometasone; topical
2.1
48.2
629
3569
N05BB01
ATC
hydroxyzine; systemic
3.2
45.8
194
646
J01CF05
ATC
flucloxacillin; systemic
3.1
44.9
202
697
H02AB06
ATC
prednisolone; systemic
1.9
44.3
935
6235
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.4
42.8
337
1547
E000006, ,
ATC
3.2
42.2
178
591
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.6
41.6
269
1125
D02AE01
ATC
carbamide; topical
3.2
41.4
177
592
E000003, ,
ATC
3.6
41.4
146
433
D07BC01
ATC
betamethasone and antiseptics; topical
2.5
38.6
260
1107
D07AD01
ATC
clobetasol; topical
2.3
38.6
349
1696
S29
ICPC
Skin symptom/complaint other
2.1
38.3
459
2492
D09AB01
ATC
zinc bandage without supplements; topical
6.4
37.8
63
101
S84
ICPC
Impetigo
7.9
35.8
49
63
L20
ICD-10 Finland
Atopic dermatitis
3.2
35.5
144
466
B00.10
ICD-10 Finland
Herpes simplex facialis
7.4
35.3
51
70
S87
ICPC
Dermatitis/atopic eczema
3.7
34.1
110
307
R06AE07
ATC
cetirizine; oral
1.8
33.6
961
6849
S76
ICPC
Skin infection other
3.3
32.8
131
420
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
32.7
824
5649
J05AB01
ATC
aciclovir; systemic
2.0
31.9
459
2640
XQ800
NOMESCO Finland
Prick test
2.4
31.0
222
969
D06AX01
ATC
fusidic acid; topical
2.4
30.9
231
1028
J01DA01
ATC
[U] cefalexin
1.7
30.3
1168
8945
70708
ICD-8 Finland
Chronic ulcer of skin, Aliud definitum
+∞
30.3
29
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
29.5
206
889
D02AX
ATC
Other emollients and protectives
3.1
29.2
124
412
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
5.9
28.9
52
90
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
28.3
248
1181
J01DA09
ATC
[U] cefadroxil
1.8
28.1
529
3298
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.7
27.8
90
252
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.1
27.7
77
193
XQ848
NOMESCO Finland
Dermatological photography
4.0
27.4
80
208
L03.9
ICD-10 Finland
Cellulitis, unspecified
6.1
26.9
47
79
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.7
26.5
62
136
S97
ICPC
Chronic ulcer skin
3.2
26.4
107
346
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.5
25.8
50
93
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
24.3
181
803
S21
ICPC
Skin texture symptom/complaint
2.0
24.1
308
1687
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
24.1
236
1173
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
8.6
22.8
29
34
D11AH05
ATC
dupilumab; topical
9.4
22.7
27
29
S01AD03
ATC
aciclovir; ophthalmic
3.5
22.4
79
234
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
22.0
387
2345
H03.8*L01.0
ICD-10 Finland
Involvement of eyelid in impetigo
+∞
21.9
21
*
501
Kela drug reimbursment
Cow's milk and / or soy protein allergy in young children
4.2
20.8
55
133
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.7
20.6
116
450
L30.0
ICD-10 Finland
Nummular dermatitis
3.1
20.6
89
299
L04AX01
ATC
azathioprine; systemic
2.8
20.5
105
388
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.1
20.1
86
287
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
20.1
425
2707
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
19.9
463
3024
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
19.8
61
165
R06AX27
ATC
desloratadine; oral
1.6
19.2
677
4894
E000007, ,
ATC
2.4
19.0
139
610
J05AB11
ATC
valaciclovir; oral
1.9
18.5
279
1606
L04AX03
ATC
methotrexate; systemic
2.1
18.5
195
994
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.4
18.4
67
203
D07XB05
ATC
dexamethasone; topical
3.5
18.3
64
189
SPAT1263
SPAT
Sampling
1.5
18.1
799
6052
H02AB04
ATC
methylprednisolone; systemic
1.9
18.0
247
1378
H02AB07
ATC
prednisone; oral
2.0
17.9
217
1162
B00.0
ICD-10 Finland
Eczema herpeticum
7.0
17.8
27
39
Z3231
NOMESCO Finland
Registered nurse
1.6
17.6
506
3475
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
17.6
355
2226
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
17.5
453
3031
N05AH04
ATC
quetiapine; oral
1.7
17.1
382
2459
N06AX16
ATC
venlafaxine; oral
1.8
17.0
301
1816
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
16.9
266
1549
L04AD01
ATC
ciclosporin; systemic
3.6
16.8
56
160
R03AC02
ATC
salbutamol; inhalant
1.5
16.6
1095
8952
J01MA12
ATC
levofloxacin; systemic
1.8
16.5
277
1645
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.7
16.4
89
339
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
16.4
179
923
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
4.5
16.4
39
87
L03.2
ICD-10 Finland
Cellulitis of face
14.4
16.3
27
19
R50.9
ICD-10 Finland
Fever, unspecified
1.7
16.1
327
2050
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.7
15.9
51
142
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
15.8
731
5551
N02AX02
ATC
tramadol; systemic, rectal
1.5
15.6
672
5022
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
15.6
355
2291
UJF32
NOMESCO Finland
Coloscopy
1.6
15.5
379
2493
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
15.4
381
2511
S01
ICPC
Pain/tenderness of skin
2.5
15.1
100
420
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
14.9
504
3572
D07XC01
ATC
betamethasone; topical
1.9
14.8
202
1123
WW200
NOMESCO Finland
Immunization
3.0
14.8
66
226
R06AE09
ATC
levocetirizine; oral
1.7
14.8
318
2020
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.0
14.8
177
943
L27.2
ICD-10 Finland
Dermatitis due to ingested food
3.1
14.7
62
206
68400
ICD-8 Finland
Impetigo, Pemphigus neonatorum
+∞
14.6
14
*
M79.6
ICD-10 Finland
Pain in limb
1.5
14.5
791
6174
B02.9
ICD-10 Finland
Zoster without complication
2.3
14.5
111
498
Z2446
NOMESCO Finland
Social worker
2.0
14.5
164
857
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
14.5
417
2849
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.3
14.4
107
474
N06AB04
ATC
citalopram; systemic
1.6
14.4
335
2173
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
14.3
176
947
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
4.5
14.2
34
76
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
14.2
262
1595
N03AX16
ATC
[U] pregabalin
1.6
14.2
344
2254
N02AA05
ATC
oxycodone; systemic
1.8
14.1
232
1367
S10
ICPC
Boil/carbuncle
2.3
14.0
103
454
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
13.9
214
1237
C03CA01
ATC
furosemide; systemic
1.6
13.8
320
2070
N05AH03
ATC
olanzapine; systemic
2.1
13.8
143
723
WZC30
NOMESCO Finland
Teaching
1.7
13.8
276
1720
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.7
13.7
43
118
N07BB01
ATC
disulfiram; oral
2.5
13.7
89
371
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
13.7
364
2438
S18
ICPC
Laceration/cut
1.4
13.6
788
6203
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.9
13.6
181
999
L04AA06
ATC
mycophenolic acid; systemic
3.3
13.6
50
153
P29
ICPC
Psychological sympt/compl other
1.8
13.4
215
1256
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.1
13.4
57
190
P01AB01
ATC
metronidazole; oral, rectal
1.5
13.4
676
5183
SPAT1229
SPAT
Assessment of need for aid
2.3
13.4
99
438
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
13.3
356
2386
H03.1*B00.5
ICD-10 Finland
Herpesviral dermatitis of eyelid
11.5
13.3
24
21
AA1AD
NOMESCO Finland
CT of head and brain
1.6
13.2
393
2699
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
13.2
213
1248
Z71.8
ICD-10 Finland
Other specified counselling
1.4
13.1
705
5461
R03BA05
ATC
fluticasone; inhalant
1.6
13.0
371
2521
R51.80
ICD-10 Finland
Headache
1.6
13.0
347
2322
T78.4
ICD-10 Finland
Allergy, unspecified
2.2
13.0
116
554
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
13.0
1068
8925
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
12.8
136
694
SPAT1310
SPAT
Counselling related to known health issue
1.5
12.8
582
4366
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
4.2
12.7
33
79
P19
ICPC
Drug abuse
4.2
12.7
33
79
H02AB09
ATC
hydrocortisone; systemic
2.7
12.7
68
258
E000004, ,
ATC
3.1
12.7
52
170
D05AX52
ATC
calcipotriol, combinations; topical
2.3
12.6
92
404
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.4
12.6
44
130
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.8
12.6
38
102
L01CD, ,
ICD-10 Finland
+∞
12.5
12
*
A02BC02
ATC
pantoprazole; systemic
1.4
12.5
1125
9521
SPAT1153
SPAT
Removal of sutures
1.5
12.5
453
3244
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
12.5
178
1004
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
20.2
12.5
18
9
J01MA02
ATC
ciprofloxacin; systemic
1.5
12.4
580
4369
N05BA01
ATC
diazepam; systemic, rectal
1.8
12.3
206
1219
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
12.3
245
1522
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
12.3
314
2079
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.5
12.3
77
316
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
12.2
366
2513
ZX112
NOMESCO Finland
Subcutaneous
3.4
12.2
43
128
L04AA01
ATC
[U] ciclosporin
4.3
12.2
31
73
A01
ICPC
Pain general/multiple sites
1.8
12.2
180
1026
R11
ICD-10 Finland
Nausea and vomiting
1.8
12.1
182
1044
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
12.1
153
831
395
Kela drug reimbursment
Dupilumab
9.3
12.0
24
26
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
11.9
293
1920
S06.0
ICD-10 Finland
Concussion
1.7
11.8
222
1358
SPAT1260
SPAT
Consultation of another employee
1.6
11.7
292
1919
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
9.0
11.7
24
27
B00.11
ICD-10 Finland
Herpes simplex labialis
2.9
11.7
54
189
S71
ICPC
Herpes simplex
4.5
11.7
28
63
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
3.6
11.6
37
103
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.6
11.5
286
1878
H62.4*L01.0
ICD-10 Finland
Otitis externa in impetigo
120.7
11.4
12
*
B18.2
ICD-10 Finland
Chronic viral hepatitis C
4.2
11.3
30
73
J01XC01
ATC
fusidic acid; systemic
4.2
11.3
30
73
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
11.2
70
287
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
4.5
11.2
27
61
D07AB01
ATC
clobetasone; topical
2.7
11.2
61
234
L23.3
ICD-10 Finland
Allergic contact dermatitis due to drugs in contact with skin
5.6
11.2
21
38
SPAT1301
SPAT
No procedures
1.4
11.1
514
3850
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
11.1
415
2982
C01CA24
ATC
epinephrine; parenteral
1.8
11.1
156
876
WZC00, ,
SPAT
1.6
11.0
305
2055
127
Kela drug reimbursment
Transplant complication
3.3
11.0
41
127
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
10.9
761
6122
R52.2
ICD-10 Finland
Other chronic pain
2.4
10.9
73
309
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.9
10.8
31
80
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.3
10.8
39
118
ZX120
NOMESCO Finland
Intravenous
1.8
10.8
152
854
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.8
10.8
32
85
K08.3
ICD-10 Finland
Retained dental root
2.0
10.8
120
624
49300
ICD-8 Finland
Asthma, bronchiale
3.1
10.7
43
139
ZY010
NOMESCO Finland
Hospital outpatient
1.9
10.7
133
717
K02.1
ICD-10 Finland
Caries of dentine
1.4
10.7
1221
10622
B07.9
ICD-10 Finland
Verruca simplex
2.2
10.5
91
430
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
10.5
195
1188
L01XA, ,
ICD-10 Finland
+∞
10.4
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
10.4
107
541
N05AX12
ATC
aripiprazole; systemic
2.0
10.4
107
541
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.1
10.3
42
137
J01AA02
ATC
doxycycline; systemic
1.4
10.3
1290
11350
H01
ICPC
Ear pain/earache
1.6
10.3
283
1902
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.0
10.3
117
613
D11AX15
ATC
[U] pimecrolimus
10.6
10.3
19
18
SPAT1255
SPAT
Intravenous administration of medicine
2.1
10.3
96
468
N05BA04
ATC
oxazepam; oral
1.5
10.2
428
3139
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.8
10.2
30
79
R06AX22
ATC
ebastine; oral
1.5
10.2
311
2138
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
10.2
154
884
ZY000
NOMESCO Finland
Hospital inpatient
3.2
10.2
39
123
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.7
10.1
31
84
N02BE01
ATC
paracetamol; systemic, rectal
1.5
10.1
1631
14955
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
10.1
199
1233
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
10.1
53
200
L73.8
ICD-10 Finland
Other specified follicular disorders
4.0
10.0
28
71
L28
ICPC
Limited function/disability (L)
1.6
10.0
239
1553
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
10.0
93
453
X58
ICD-10 Finland
Exposure to other specified factors
1.5
9.9
308
2125
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.8
9.8
162
954
A07EC02
ATC
mesalazine; oral, rectal
2.0
9.8
104
532
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.3
9.7
36
111
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.6
9.7
256
1704
WX002
NOMESCO Finland
Sedation and analgesia
1.6
9.7
269
1811
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.1
9.7
40
132
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.7
802
6600
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.6
9.7
31
87
L28.1
ICD-10 Finland
Prurigo nodularis
5.3
9.6
19
36
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
9.6
105
543
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
9.6
310
2158
D07AC14
ATC
methylprednisolone aceponate; topical
2.1
9.6
84
400
L12
ICPC
Hand/finger symptom/complaint
1.5
9.6
343
2439
B01AB05
ATC
enoxaparin; parenteral
1.4
9.5
427
3169
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.0
9.5
41
139
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.9
9.5
127
703
F10.24
ICD-10 Finland
Alcohol depence active use
3.3
9.5
35
108
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.4
875
7318
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.8
9.3
46
168
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
9.3
507
3894
R95
ICPC
Chron obstructive pulmonary disease
3.0
9.3
39
130
N03AX12
ATC
[U] gabapentin; oral
1.6
9.3
231
1516
SPAT1312
SPAT
General health counselling
1.4
9.2
610
4835
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
4.1
9.2
25
62
L20.8
ICD-10 Finland
Other atopic dermatitis
3.2
9.2
36
115
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
9.2
1168
10211
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
3.3
9.2
34
105
L30.8
ICD-10 Finland
Other specified dermatitis
2.4
9.2
60
252
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
9.2
141
814
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.8
9.2
126
703
L04AB04
ATC
adalimumab; parenteral
2.5
9.2
55
222
L02.1
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of neck
7.8
9.1
20
26
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
9.1
186
1162
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
9.1
227
1490
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.1
9.1
37
121
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
9.1
157
938
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.6
9.1
230
1516
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
8.3
9.1
19
23
N05AF03
ATC
chlorprothixene; systemic
2.6
9.0
49
188
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.3
9.0
64
279
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.0
607
4826
L71.8
ICD-10 Finland
Other rosacea
3.1
9.0
36
117
F03
ICPC
Eye discharge
1.8
8.9
147
866
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.2
8.9
75
352
R03BA01
ATC
beclometasone; inhalant
1.6
8.9
209
1354
R06AX13
ATC
loratadine; oral
1.5
8.8
286
1990
R60.0
ICD-10 Finland
Localized oedema
1.7
8.8
167
1023
D06BB03
ATC
aciclovir; topical
2.1
8.8
80
387
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
8.8
84
414
S06
ICPC
Rash localized
2.0
8.8
99
518
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.7
543
4257
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
8.7
125
707
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
8.7
122
685
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.7
374
2751
N05AA02
ATC
levomepromazine; systemic
2.3
8.7
67
303
S99
ICPC
Skin disease other
2.8
8.7
42
152
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.1
8.7
85
423
N05CD07
ATC
temazepam; oral
1.8
8.6
129
739
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.4
8.6
56
235
J20
ICD-10 Finland
Acute bronchitis
1.6
8.6
182
1148
L91.0
ICD-10 Finland
Hypertrophic scar
3.1
8.6
35
115
Z00.0
ICD-10 Finland
General medical examination
1.5
8.5
347
2526
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
8.5
188
1199
L26
ICD-10 Finland
Exfoliative dermatitis
20.1
8.5
12
6
ZXD05
NOMESCO Finland
Urgent procedure
1.4
8.4
495
3841
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.4
241
1632
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
4.3
8.4
21
49
S01GX02
ATC
levocabastine; ophthalmic
1.9
8.4
107
584
R03BB04
ATC
tiotropium bromide; inhalant
1.8
8.4
122
694
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
3.4
8.4
29
86
48609
ICD-8 Finland
Pneumonia, unspecified
3.3
8.4
31
96
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.5
8.3
329
2379
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
8.3
272
1896
J01CF02
ATC
cloxacillin; systemic
3.1
8.3
34
112
WX892
NOMESCO Finland
Monitored bed care
1.8
8.3
120
681
R03AC03
ATC
terbutaline; inhalant
1.5
8.3
230
1548
N02BF02
ATC
pregabalin; oral
1.8
8.1
112
626
Z02.7
ICD-10 Finland
Issue of medical certificate
1.7
8.1
137
814
N06AX21
ATC
duloxetine; oral
1.6
8.1
196
1278
A28
ICPC
Limited function/disability NOS
1.6
8.1
194
1263
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
8.0
699
5752
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.3
8.0
57
249
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
8.0
202
1329
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
4.1
8.0
21
51
N06AB03
ATC
fluoxetine; oral
1.6
8.0
206
1363
L17
ICPC
Foot/toe symptom/complaint
1.4
8.0
517
4072
D07CB01
ATC
triamcinolone and antibiotics; topical
3.0
7.9
34
115
N05CF01
ATC
zopiclone; oral
1.4
7.9
434
3326
F61.0
ICD-10 Finland
Mixed personality disorders
2.9
7.9
36
126
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
7.9
119
684
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.6
7.9
25
70
EBA30
NOMESCO Finland
Extraction of root of tooth
2.0
7.8
82
418
J01CE08
ATC
benzathine benzylpenicillin; parenteral
6.1
7.8
20
33
ICB06, ,
NOMESCO Finland
3.0
7.8
34
116
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
2.8
7.8
37
133
N06AX12
ATC
bupropion; oral
1.6
7.8
167
1058
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
7.7
53
228
L70.0
ICD-10 Finland
Acne vulgaris
1.9
7.7
100
548
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
7.7
103
571
R06.0
ICD-10 Finland
Dyspnoea
1.4
7.7
394
2986
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.2
7.6
62
287
UDC00
NOMESCO Finland
Ear microscopy
1.7
7.6
132
790
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.7
7.6
18
27
S04
ICPC
Lump/swelling localized
1.5
7.6
208
1396
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
2.8
7.6
37
135
P74
ICPC
Anxiety disorder/anxiety state
1.7
7.6
126
746
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.7
7.5
135
815
A08
ICPC
Swelling
2.0
7.5
78
397
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.5
680
5618
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.5
462
3606
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.5
415
3184
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.0
7.5
31
103
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.0
7.5
76
384
R96
ICPC
Asthma
1.6
7.5
156
981
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.5
7.5
251
1758
J01FA01
ATC
erythromycin; systemic
1.5
7.4
249
1742
R04.0
ICD-10 Finland
Epistaxis
1.8
7.4
103
577
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
7.4
285
2048
L50.0
ICD-10 Finland
Allergic urticaria
2.2
7.4
59
271
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.2
7.4
28
88
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.9
7.4
34
120
D11
ICPC
Diarrhoea
1.5
7.4
252
1771
L71.9
ICD-10 Finland
Rosacea, unspecified
2.4
7.4
47
196
L01BA01
ATC
methotrexate; systemic
2.3
7.3
55
247
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
2.6
7.3
40
155
134
Kela drug reimbursment
General erythroderma
6.8
7.3
17
25
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
9.4
7.3
14
15
A92
ICPC
Allergy/allergic reaction NOS
1.9
7.3
86
458
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.9
7.3
90
487
H04AA01
ATC
glucagon; nasal, parenteral
2.2
7.3
58
267
EB1VA, ,
NOMESCO Finland
1.4
7.2
313
2300
P76
ICPC
Depressive disorder
1.6
7.2
153
966
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
7.2
78
403
A04AA01
ATC
ondansetron; systemic, rectal
1.7
7.2
122
726
R02
ICPC
Shortness of breath/dyspnoea
1.5
7.2
203
1372
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.1
171
1112
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
7.1
101
570
IHZ04, ,
SPAT
2.4
7.1
46
193
M54.5
ICD-10 Finland
Low back pain
1.3
7.1
631
5188
L50.3
ICD-10 Finland
Dermatographic urticaria
2.6
7.1
40
157
H01.0
ICD-10 Finland
Blepharitis
1.7
7.1
137
844
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.1
995
8684
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
2.7
7.1
36
134
J01MA14
ATC
moxifloxacin; systemic
1.7
7.1
125
752
H19.1
ICD-10 Finland
Herpesviral keratitis and keratoconjunctivitis
12.1
7.1
12
10
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.9
7.1
32
112
P17
ICPC
Tobacco abuse
2.9
7.1
32
112
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
2.4
7.1
47
200
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
7.1
164
1059
L04AD02
ATC
tacrolimus; systemic
3.0
7.0
29
96
13300, ,
ICD-8 Finland
8.8
7.0
14
16
XW000
NOMESCO Finland
Bone marrow biopsy
2.2
7.0
59
277
B35.3
ICD-10 Finland
Tinea pedis
1.9
7.0
84
449
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.0
1457
13367
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
1.6
7.0
171
1118
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.3
6.9
49
214
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.6
6.9
162
1047
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.5
6.9
43
177
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.8
6.9
95
531
T82
ICPC
Obesity
1.9
6.9
80
423
P18
ICPC
Medication abuse
4.0
6.9
19
48
R03BA02
ATC
budesonide; inhalant
1.4
6.9
309
2285
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.9
217
1500
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
6.9
1289
11650
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
6.8
68
341
L29.8
ICD-10 Finland
Other pruritus
3.0
6.8
29
98
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.8
715
6006
03599
ICD-8 Finland
Erysipelas
9.3
6.8
13
14
K10.3
ICD-10 Finland
Alveolitis of jaws
1.8
6.8
95
535
Z51.5
ICD-10 Finland
Palliative care
1.9
6.8
88
484
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
4.3
6.7
17
40
A02BC01
ATC
omeprazole; systemic
1.4
6.7
383
2947
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
3.9
6.7
19
49
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.5
6.7
41
168
WZC30, ,
SPAT
1.7
6.7
130
803
IGY02, ,
SPAT
2.5
6.7
40
162
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
6.7
84
457
K50.8
ICD-10 Finland
Other Crohn disease
2.7
6.7
34
127
45400
ICD-8 Finland
Varicose veins of lower extremities, With ulcer
22.6
6.7
9
*
SPAT1254
SPAT
Administration of medicine
1.5
6.7
253
1814
N03AG01
ATC
valproic acid; systemic, rectal
1.7
6.7
106
620
J45
ICD-10 Finland
Asthma
1.5
6.6
179
1196
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.6
221
1544
E66.8
ICD-10 Finland
Other obesity
1.8
6.6
99
568
N06AX11
ATC
mirtazapine; oral
1.3
6.6
547
4445
L12.0
ICD-10 Finland
Bullous pemphigoid
6.4
6.6
16
25
SPAT1240
SPAT
Therapeutic discussion
1.5
6.6
226
1587
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.3
6.6
47
206
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
6.6
185
1247
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
3.6
6.6
21
59
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.9
6.6
82
445
QDB10, ,
SPAT
2.6
6.5
36
140
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.0
6.5
70
361
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.6
6.5
37
146
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
3.8
6.5
19
50
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.7
6.5
125
770
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.8
6.5
94
535
J01AA07
ATC
tetracycline; systemic
1.4
6.5
258
1866
N05BE01
ATC
buspirone; oral
2.2
6.5
51
234
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.5
545
4440
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
6.4
1400
12833
Z3226
NOMESCO Finland
Physiotherapist
1.4
6.4
281
2069
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
6.4
58
282
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.8
6.4
19
51
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
6.6
6.3
15
23
N91.1
ICD-10 Finland
Secondary amenorrhoea
2.2
6.3
48
217
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.3
411
3226
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.3
290
2153
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.3
6.3
412
3237
Z00.8
ICD-10 Finland
Other general examinations
1.6
6.3
148
960
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.3
237
1698
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.3
212
1487
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.7
6.3
32
120
L01XC, ,
ICD-10 Finland
+∞
6.3
6
*
L01BC, ,
ICD-10 Finland
+∞
6.3
6
*
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
2.2
6.2
52
244
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.2
6.2
48
218
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
6.2
152
993
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
6.2
150
977
IGV01
NOMESCO Finland
Psychiatric network contact
2.4
6.2
41
174
J01FA06
ATC
roxithromycin; oral
1.3
6.2
594
4916
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.0
6.2
63
319
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
6.2
556
4564
H60.3
ICD-10 Finland
Other infective otitis externa
2.3
6.2
46
206
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
6.2
76
411
N05AX08
ATC
risperidone; systemic
1.6
6.2
124
773
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.2
319
2414
D50.8
ICD-10 Finland
Other iron deficiency anaemias
2.9
6.2
27
93
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.5
6.2
20
57
ZYC03
NOMESCO Finland
Remote contact, text-based
5.3
6.1
17
32
B86
ICD-10 Finland
Scabies
1.9
6.1
68
355
K04.08
ICD-10 Finland
Other specified pulpit
1.5
6.1
161
1070
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
3.3
6.1
22
67
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
3.3
6.1
22
67
D05BB02
ATC
acitretin; oral
2.5
6.1
36
145
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.9
6.1
28
99
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.3
6.1
45
201
JN4BD
NOMESCO Finland
Extensive body CT
1.7
6.1
114
698
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.7
6.1
31
116
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.8
6.1
88
501
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
4.1
6.1
16
39
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
2.0
6.1
64
329
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
3.1
6.0
24
78
D01AC02
ATC
miconazole; topical
1.7
6.0
98
578
F41.09
ICD-10 Finland
UNS Panic Syndrome
1.9
6.0
68
358
XF602
NOMESCO Finland
Bloodpressure monitoring
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
516
1896
3.31
108.53
2.2
1.6
—
—
—
0
0
647
3701
2.10
48.57
5.8
4.0
—
—
—
0
0
1219
9101
1.85
38.28
10.3
6.8
0.58
0.56
e9/l
2.84
1086
7867
1147
8409
1.83
38.18
10.2
6.9
3.05
2.85
%
1.66
1104
7963
1219
9111
1.84
38.03
10.4
6.9
0.04
0.04
e9/l
0.86
1087
7875
1143
8395
1.82
37.57
10.5
7.0
0.69
0.68
%
0.54
1096
7946
400
2077
2.15
37.43
2.3
1.9
—
—
—
0
0
1145
8435
1.82
37.04
10.5
7.0
8.46
8.57
%
0.75
1103
7999
1245
9413
1.83
36.89
11.0
7.2
0.21
0.19
e9/l
3.00
1127
8282
1236
9360
1.82
36.04
10.5
6.8
1.95
2.05
e9/l
1.87
1131
8316
1301
10047
1.82
35.08
14.7
9.6
4.08
3.93
e9/l
1.68
1167
8738
1149
8585
1.78
34.32
9.9
6.7
56.06
55.33
%
1.25
1112
8276
1159
8751
1.75
32.70
10.2
6.8
28.86
30.10
%
3.30
1121
8384
926
6632
1.73
30.96
6.7
5.3
36.39
36.82
g/l
1.52
874
6261
169
648
2.75
30.79
1.3
1.2
—
—
—
0
0
1483
12268
1.77
27.84
11.1
7.4
82.03
80.01
u/l
0.82
1425
11707
1006
7562
1.65
26.60
10.7
7.5
1.21
1.21
mmol/l
0.32
882
6607
1064
8153
1.64
25.75
8.8
6.3
10.85
12.46
umol/l
2.60
1005
7730
643
4463
1.64
22.27
3.3
2.6
—
—
—
0
0
693
4948
1.61
21.16
4.0
2.5
57.54
59.73
u/l
0.41
650
4622
293
1653
1.90
20.83
7.2
6.0
1.66
1.49
mmol/l
0.35
259
1390
893
6786
1.56
20.73
9.7
7.3
1.21
1.21
mmol/l
0.48
838
6330
1173
9475
1.56
20.72
6.7
5.2
6.55
6.40
mmol/l
1.34
1114
8815
275
1526
1.93
20.53
1.7
1.3
1475.93
272.16
u/ml
3.76
259
1427
841
6324
1.56
20.34
12.0
10.5
1.18
1.18
inr
0.03
706
5249
1452
12351
1.61
20.23
5.7
4.1
11.56
9.54
mm/h
5.99
1368
11659
617
4348
1.60
19.59
3.1
2.3
2.68
2.67
mg/l
0.03
553
3801
399
2521
1.72
19.37
6.2
4.7
0.80
0.82
mmol/l
2.92
386
2408
293
1691
1.86
19.32
7.4
5.9
5.87
5.81
kpa
0.55
287
1647
331
1993
1.79
18.98
1.9
1.5
—
—
—
0
0
979
7693
1.52
18.91
3.1
2.6
74.19
73.78
nmol/l
0.17
903
7179
264
1502
1.87
18.16
3.6
3.0
10.71
10.30
g/l
0.82
249
1402
292
1715
1.82
18.14
7.3
5.9
7.37
7.37
ph
0.32
193
1030
221
1189
1.96
17.99
3.9
3.6
65.60
69.33
e9/l
0.85
167
848
421
2762
1.66
17.58
1.9
1.6
—
—
—
0
0
348
2172
1.73
17.50
9.8
7.1
1.11
1.11
mmol/l
0.18
330
2038
257
1484
1.84
16.81
7.2
5.6
4.80
4.78
kpa
0.03
249
1445
397
2601
1.65
16.56
3.2
2.6
13.19
14.33
umol/l
1.83
379
2442
276
1637
1.79
16.52
4.9
3.8
1.63
1.66
%
0.23
255
1495
399
2621
1.65
16.47
1.5
1.4
626.99
506.33
titre
0.45
83
515
240
1365
1.86
16.47
5.1
4.8
0.72
0.63
%
0.22
79
397
249
1436
1.84
16.34
5.3
5.0
0.81
0.91
%
0.23
92
423
213
1169
1.92
16.31
2.4
1.9
1.45
1.32
g/l
0.27
203
1099
497
3462
1.58
16.05
3.6
2.6
6.03
6.50
e6/l
0.34
470
3151
592
4302
1.53
15.77
5.7
3.8
7.40
7.39
ph
0.46
453
3020
1866
17283
1.95
15.67
21.7
12.6
21.68
21.68
mg/l
0.00
1587
13733
1283
10901
1.48
15.44
5.4
4.1
488.37
1142.15
e6/l
0.52
19
134
336
2146
1.68
15.37
3.2
2.7
21.84
23.98
%
1.93
322
2013
253
1505
1.78
14.93
7.9
9.2
1.24
0.72
mmol/l
1.48
214
1228
436
2995
1.58
14.81
3.6
2.7
517.36
545.64
mosm/kgh2o
1.80
400
2639
359
2369
1.63
14.38
3.1
2.6
2.36
2.42
g/l
1.22
341
2204
253
1526
1.75
14.21
8.0
9.2
7.42
7.41
ph
0.44
140
805
250
1510
1.75
13.96
3.3
2.8
0.22
0.22
g/l
0.29
233
1429
121
572
2.19
13.92
2.6
1.7
0.22
0.23
g/l
0.64
111
542
229
1353
1.78
13.80
8.3
9.8
95.64
95.76
%
0.07
218
1308
531
3865
1.51
13.71
3.6
2.7
333.97
330.83
umol/l
0.31
474
3510
105
471
2.30
13.71
2.5
2.2
260.98
366.19
ug/l
0.46
97
445
588
4385
1.48
13.42
2.5
2.2
158.06
238.27
u/l
1.91
567
4193
681
5228
1.45
13.37
3.8
3.1
35.82
57.64
ng/l
0.57
437
3077
520
3787
1.50
13.33
2.6
2.1
0.85
1.11
mg/l
2.39
400
2816
674
5181
1.45
13.08
4.5
3.2
40.01
72.77
e6/l
0.90
557
3871
406
2815
1.55
13.06
3.8
2.7
147.41
106.78
ug/g
1.16
342
2284
579
4325
1.47
13.04
7.1
4.5
—
—
—
0
0
802
6373
1.43
12.96
2.1
1.9
91.53
96.55
pmol/l
3.17
476
3518
540
3984
1.48
12.93
1.8
1.6
19.79
19.90
nmol/l
0.06
472
3483
283
1804
1.66
12.91
3.1
2.3
336.14
372.32
nmol/l
2.14
272
1700
973
8014
1.41
12.76
16.2
10.4
0.00
0.00
e9/l
0.36
811
6512
231
1403
1.73
12.61
5.7
5.3
0.96
0.34
%
0.29
66
344
229
1389
1.73
12.56
5.5
5.1
0.06
0.13
%
1.41
72
376
245
1521
1.69
12.34
10.8
10.1
—
—
—
0
0
592
4481
1.45
12.32
1.7
1.5
2.11
2.16
g/l
0.30
391
2871
246
1530
1.69
12.31
8.2
9.1
5.11
5.12
kpa
0.09
237
1469
246
1530
1.69
12.31
8.1
9.1
12.63
12.95
kpa
0.44
236
1472
1096
9248
1.40
12.30
4.5
3.5
0.00
0.18
estimate
0.53
236
1773
349
2368
1.57
12.29
3.6
3.2
29.48
29.51
s
0.04
338
2313
669
5182
1.43
12.29
3.5
3.2
2.35
2.36
mmol/l
0.43
613
4801
119
588
2.09
12.24
2.7
1.7
1.18
1.19
g/l
0.09
112
559
633
4857
1.44
12.23
4.3
3.6
0.00
0.01
estimate
1.54
237
1753
303
1994
1.61
12.14
1.8
1.7
1061.45
1173.87
nmol/l
1.30
238
1539
57
202
2.87
12.10
2.7
2.9
1432.46
1373.71
e6/l
0.16
50
166
1089
9204
1.39
11.96
4.4
3.5
0.00
6.94
estimate
2.30
250
1861
35
92
3.85
11.92
5.6
4.9
10.41
9.44
mg/l
0.27
28
82
275
1785
1.62
11.63
1.6
1.5
—
—
—
0
0
1078
9121
1.39
11.62
4.5
3.5
0.00
0.00
estimate
0.80
245
1860
316
2122
1.58
11.60
3.8
3.0
4.23
4.72
e9/l
0.80
272
1909
776
6234
1.40
11.35
5.2
3.8
77.09
74.64
e6/l
0.04
591
4157
1807
16841
1.65
11.31
22.2
13.8
139.42
139.63
mmol/l
3.62
1778
16491
289
1914
1.59
11.23
3.7
3.3
7.52
7.01
umol/l
0.16
242
1654
901
7431
1.38
11.20
4.1
3.1
6.23
6.21
ph
0.23
530
4254
1810
16887
1.65
11.15
22.4
13.9
3.94
3.94
mmol/l
0.16
1777
16499
736
5878
1.39
11.08
4.6
3.4
31.00
30.97
u/l
0.01
697
5589
555
4225
1.43
10.98
1.9
1.8
—
—
—
0
0
192
1152
1.74
10.92
3.2
2.4
0.62
0.34
e6/l
0.37
182
1095
108
538
2.06
10.89
2.2
2.1
1.36
1.39
g/l
0.09
94
478
227
1427
1.66
10.87
13.2
9.3
7.55
7.63
mmol/l
0.07
221
1386
49
170
2.93
10.84
2.7
3.0
213.00
215.60
e6/l
0.03
41
135
464
3424
1.46
10.83
4.0
3.4
1344.07
1004.86
ng/l
0.75
394
2857
403
2900
1.49
10.67
1.7
1.6
26100146.25
32021110.70
pmol/l
0.08
341
2514
75
326
2.35
10.58
4.3
3.3
—
—
—
0
0
937
7835
1.36
10.43
3.4
2.7
—
—
estimate
—
0
0
218
1374
1.66
10.33
3.1
2.4
7619.47
6839.67
u/l
0.11
76
533
86
401
2.19
10.29
4.7
6.9
1.26
1.26
mmol/l
0.00
78
348
131
714
1.89
10.23
1.3
1.2
0.18
1.30
u/ml
1.28
13
47
214
1347
1.66
10.19
8.0
6.3
5.11
5.08
kpa
0.25
206
1299
581
4510
1.40
10.16
4.3
3.1
0.21
0.36
e6/l
3.26
464
3218
211
1328
1.66
10.05
8.0
6.3
7.41
7.41
ph
0.41
179
1085
98
486
2.07
10.02
1.9
1.9
1.44
2.05
ug/l
0.37
81
430
47
167
2.86
9.98
2.7
3.0
606.85
586.48
e6/l
0.08
39
127
663
5283
1.38
9.85
2.4
2.2
—
—
—
0
0
212
1358
1.63
9.41
10.2
9.7
1.32
1.31
mmol/l
0.08
206
1327
134
757
1.82
9.36
2.3
1.9
6.60
7.61
iu/ml
0.16
36
174
1507
13706
1.38
9.08
4.8
4.2
14.48
14.53
pmol/l
0.40
1407
12778
637
5097
1.36
9.06
1.6
1.4
1.22
1.80
u/ml
1.04
163
1375
661
5329
1.36
8.93
3.1
2.3
—
—
—
0
0
164
1000
1.70
8.81
1.7
1.4
—
—
—
0
0
831
6944
1.33
8.79
4.3
3.2
0.00
0.03
estimate
2.11
214
1564
33
103
3.24
8.77
43.1
44.0
7.26
7.04
ug/l
0.24
27
94
55
227
2.46
8.75
3.8
3.8
1.67
1.33
%
0.28
49
212
169
1041
1.68
8.74
3.5
2.8
66.82
67.12
g/l
0.18
160
979
139
817
1.75
8.52
10.3
11.6
24.71
24.21
mmol/l
1.13
134
804
1899
18121
1.71
8.45
24.5
15.0
72.73
72.16
umol/l
0.33
1878
17917
524
4103
1.37
8.44
4.2
3.4
1.02
1.76
kg/l
0.80
352
2702
147
883
1.72
8.34
3.6
3.3
138.95
165.01
ng/l
0.34
131
798
132
770
1.76
8.31
3.7
3.6
20.83
21.12
s
0.35
117
693
76
369
2.10
8.27
2.4
3.1
33.07
34.02
umol/l
0.11
71
347
1891
18053
1.66
8.03
15.8
10.3
27.22
26.70
u/l
0.54
1854
17625
1375
12421
1.33
8.02
4.2
3.3
45.61
40.83
u/l
1.23
1311
11918
161
1007
1.65
7.86
1.3
1.2
—
—
—
0
0
33
111
3.00
7.78
2.3
3.1
1245.48
831.43
u/ml
0.53
33
111
31
104
3.01
7.35
31.1
34.2
116.04
136.24
ug/l
0.70
25
89
1066
9363
1.29
7.33
3.7
3.2
96.85
96.05
ug/l
0.06
1008
8879
635
5212
1.32
7.28
9.1
5.9
—
—
—
0
0
37
138
2.71
7.26
3.2
3.3
59.87
54.03
%
0.79
30
127
65
315
2.10
7.15
4.1
3.4
4.71
3.90
e9/l
1.77
65
315
17
26
6.58
7.11
1.2
2.0
—
—
—
0
0
167
1082
1.59
7.08
4.7
3.4
1.23
1.23
mmol/l
0.27
149
930
425
3300
1.36
7.07
1.4
1.3
20.96
25.48
iu/ml
0.69
118
933
60
284
2.15
7.02
5.0
3.4
2.30
2.23
mmol/l
0.07
40
178
128
778
1.69
6.99
3.2
2.5
—
—
—
0
0
47
203
2.35
6.84
1.4
1.3
—
—
—
0
0
515
4144
1.32
6.71
6.1
4.5
91.11
92.13
%
0.42
504
4058
44
187
2.38
6.64
6.8
7.2
9.83
10.60
mg/l
0.51
39
172
623
5162
1.30
6.52
4.7
3.5
7.79
8.31
mmol/l
1.75
552
4548
558
4559
1.31
6.48
3.5
3.0
—
0.75
—
0
12
360
2764
1.37
6.38
3.7
2.9
1.18
0.99
e6/l
0.64
214
1396
504
4069
1.32
6.37
3.1
2.3
—
—
—
0
0
62
309
2.04
6.37
3.6
3.9
4.03
2.07
ratio
0.73
41
174
102
601
1.73
6.26
5.0
2.5
—
—
—
0
0
46
205
2.27
6.26
1.4
1.3
7.03
6.51
g/l
0.45
34
161
46
205
2.27
6.26
1.4
1.3
2.49
2.80
g/l
0.70
35
159
46
205
2.27
6.26
1.4
1.3
0.53
0.38
g/l
0.51
35
159
1690
15925
1.36
6.21
5.9
5.0
2.02
1.83
mu/l
0.42
1604
15075
95
551
1.76
6.17
2.0
1.5
218.38
230.59
u/ml
0.13
47
328
222
1579
1.46
6.10
3.2
2.3
30.64
66.50
u/l
0.62
187
1332
18
48
3.77
6.09
1.1
2.1
—
—
—
0
0
385
3016
1.34
5.96
1.3
1.3
9.87
9.95
u/ml
0.01
144
1238
87
498
1.78
5.92
1.3
1.3
2.43
12.53
u/ml
1.69
13
75
626
5246
1.28
5.89
3.3
2.7
0.00
0.05
—
8
65
53
258
2.08
5.82
5.0
3.7
—
—
—
0
0
86
499
1.75
5.60
1.3
1.3
1.56
2.50
u/ml
—
9
43
81
462
1.78
5.59
4.0
3.0
58.99
57.22
%
0.58
81
462
161
1093
1.51
5.58
6.0
5.1
75.45
74.63
ng/l
0.05
141
997
83
481
1.76
5.44
1.9
1.7
—
—
—
0
0
343
2677
1.34
5.42
2.7
2.7
2.43
2.43
mmol/l
0.28
299
2405
141
938
1.54
5.38
8.6
7.1
24.74
24.41
mmol/l
0.64
136
902
32
130
2.48
5.37
1.3
1.2
16.39
7.33
u/ml
0.25
26
96
63
337
1.90
5.34
1.1
1.1
—
—
—
0
0
35
150
2.36
5.25
2.7
1.3
1.69
1.23
promille
0.80
29
124
138
920
1.54
5.22
2.1
1.7
0.38
0.31
mg/l
0.71
65
442
346
2720
1.33
5.19
4.9
3.5
206.45
570.27
ng/l
3.48
225
1812
65
355
1.86
5.18
3.7
4.0
67.79
59.89
mg/l
0.13
57
303
65
355
1.86
5.18
3.7
4.0
26.62
43.37
mg/l
1.23
56
304
63
341
1.87
5.17
1.1
1.1
—
—
—
0
0
47
231
2.06
5.08
1.8
1.6
—
—
—
0
0
61
330
1.87
5.02
1.6
1.6
0.77
0.71
g/l
0.13
46
268
150
1027
1.50
5.02
8.9
6.8
—
—
—
0
0
70
396
1.79
5.00
4.8
3.0
5.16
3.33
index
0.31
37
223
151
1040
1.49
4.91
4.6
2.4
—
—
—
0
0
189
2569
0.71
4.83
1.7
1.8
3.44
3.49
ratio
0.24
144
1908
237
1779
1.38
4.81
1.5
1.4
—
—
—
0
0
91
561
1.65
4.80
1.3
1.3
—
—
—
0
0
28
113
2.50
4.79
3.0
3.1
0.37
0.36
e9/l
0.02
18
63
33
145
2.30
4.71
1.2
1.1
103.03
114.31
pmol/l
0.71
33
145
328
2594
1.31
4.70
4.0
3.0
2.85
2.64
e6/l
0.16
179
1227
46
232
2.01
4.66
1.3
1.3
3.72
2.84
u/ml
0.11
29
117
1588
14997
1.27
4.61
5.7
5.1
38.41
37.75
mmol/mol
1.84
1488
14293
45
227
2.00
4.56
1.4
1.3
2.17
3.77
u/ml
0.42
27
98
97
618
1.60
4.50
4.7
4.6
326.14
349.04
mg/l
0.07
59
322
77
463
1.69
4.48
1.9
1.7
115.51
141.27
au/ml
0.90
21
136
36
168
2.16
4.47
4.3
4.1
—
—
—
0
0
1967
19223
1.68
4.39
31.6
19.3
90.14
89.90
fl
1.43
1955
19078
1967
19226
1.68
4.35
31.6
19.2
30.10
30.06
pg
0.47
1956
19081
1967
19226
1.68
4.35
32.4
19.8
40.22
41.60
%
2.54
1954
19070
412
3389
1.27
4.35
2.0
1.9
—
—
—
0
0
40
197
2.05
4.34
1.4
1.4
373.74
438.71
pmol/l
0.29
34
172
1967
19227
1.67
4.33
31.7
19.3
4.50
4.57
e12/l
9.41
1931
18821
607
5220
1.23
4.31
3.9
2.8
0.00
0.07
estimate
1.02
218
1521
1967
19230
1.67
4.29
31.7
19.4
7.00
6.74
e9/l
3.56
1932
18810
23
90
2.57
4.22
2.0
2.4
288.33
154.09
umol/l
0.43
12
46
1967
19235
1.66
4.22
32.0
19.5
134.45
136.65
g/l
9.55
1956
19089
33
153
2.18
4.18
1.1
1.0
—
—
—
0
0
142
1976
0.70
4.16
1.5
1.6
3.42
3.44
mmol/l
0.09
105
1330
1965
19215
1.64
4.15
31.8
19.3
261.98
257.68
e9/l
2.09
1936
18851
234
1800
1.34
4.07
1.3
1.2
—
—
—
0
0
160
1161
1.41
3.99
4.0
4.4
34.35
20.54
ug/l
0.30
130
916
46
248
1.87
3.90
2.2
1.6
57.41
69.22
mmol/l
1.05
39
209
41
213
1.94
3.88
2.4
2.1
—
—
—
0
0
269
2129
1.30
3.83
1.3
1.2
—
—
—
0
0
1625
15481
1.25
3.81
4.7
4.2
5.83
5.73
mmol/l
1.67
1500
14506
16
55
2.92
3.73
1.0
1.2
1.09
3.42
u/ml
0.67
11
42
40
209
1.93
3.73
1.4
1.3
—
—
—
0
0
19
72
2.65
3.73
1.0
1.1
218.68
236.34
iu/ml
0.09
19
72
28
128
2.20
3.70
2.5
1.8
—
—
—
0
0
161
1186
1.39
3.70
3.9
1.9
—
—
—
0
0
104
707
1.50
3.67
3.9
2.8
1.02
1.02
ratio
0.43
96
636
68
419
1.64
3.67
1.2
1.2
47.31
37.71
u/ml
—
9
33
164
1214
1.38
3.66
1.7
1.5
—
—
—
0
0
86
562
1.55
3.64
1.4
1.3
—
—
—
0
0
59
351
1.70
3.63
2.5
2.4
128.54
132.27
g/l
0.55
52
287
99
668
1.51
3.62
1.3
1.1
4.18
2.03
u/ml
0.95
80
394
31
150
2.08
3.57
1.6
2.1
0.65
3.98
u/ml
—
7
57
57
338
1.71
3.56
1.6
1.6
11805.13
14074.17
e6/l
0.18
45
243
26
119
2.20
3.45
1.2
1.1
1.07
1.05
ratio
0.18
19
103
166
1244
1.36
3.45
5.6
3.8
7.37
7.34
ph
1.32
122
925
49
281
1.76
3.44
1.6
1.7
—
—
—
0
0
49
281
1.76
3.44
1.6
1.7
—
—
—
0
0
49
281
1.76
3.44
1.6
1.7
—
—
—
0
0
49
281
1.76
3.44
1.6
1.7
—
—
—
0
0
10
22
4.56
3.43
1.1
1.1
0.13
0.02
u/ml
—
10
22
71
452
1.59
3.38
4.1
3.7
1216.89
947.21
u/ml
0.09
61
390
161
1205
1.36
3.37
1.2
1.2
35.00
135.62
titre
—
6
34
27
127
2.14
3.36
1.2
1.1
—
—
—
0
0
490
4216
1.21
3.36
4.8
4.2
45.36
8.61
mg/mmol
0.55
324
2750
187
1435
1.33
3.33
4.8
3.5
—
—
—
0
0
16
59
2.72
3.32
1.4
1.6
—
—
—
0
0
68
434
1.59
3.22
2.8
1.9
6.34
17.09
e6/l
0.93
53
313
69
442
1.58
3.22
2.8
1.9
107.42
1753.24
e6/l
1.43
59
334
50
296
1.71
3.17
1.2
1.2
—
—
—
0
0
65
413
1.59
3.14
2.9
1.9
—
—
—
0
0
482
4165
1.21
3.14
4.1
3.6
103.35
53.26
mg/l
0.63
328
2770
72
469
1.55
3.14
1.6
1.4
279.38
304.40
ug/g
0.42
37
260
15
56
2.69
3.05
2.3
2.1
33.00
29.02
%
0.46
15
56
40
225
1.79
3.03
2.4
2.3
—
—
—
0
0
178
1387
1.31
2.88
3.8
1.9
—
—
—
0
0
105
754
1.41
2.85
1.3
1.2
4.46
2.95
u/ml
0.38
76
453
183
2308
0.77
2.83
1.3
1.3
—
—
—
0
0
28
144
1.96
2.80
1.1
1.1
—
—
—
0
0
8
18
4.46
2.79
1.3
1.2
—
—
—
0
0
15
59
2.55
2.78
1.2
2.1
—
—
—
0
0
59
380
1.57
2.74
1.4
1.2
—
—
—
0
0
27
139
1.95
2.70
1.5
1.4
—
—
—
0
0
24
119
2.03
2.66
1.3
1.3
11.53
13.49
u/ml
0.07
19
84
96
689
1.41
2.64
1.2
1.1
7.23
5.15
u/ml
0.47
73
433
33
184
1.81
2.61
1.2
1.4
4.20
3.03
u/ml
0.24
25
106
51
322
1.60
2.59
1.4
1.3
1.88
4.72
u/ml
2.15
26
145
188
1499
1.28
2.57
3.6
1.8
—
—
—
0
0
16
68
2.36
2.55
3.1
3.0
14.69
17.10
%
1.48
16
68
5
7
7.15
2.55
1.0
1.3
—
—
—
0
0
187
1493
1.28
2.54
3.7
1.8
—
—
—
0
0
90
644
1.42
2.53
2.2
2.2
—
—
—
0
0
144
1111
1.32
2.53
1.7
1.7
366.90
304.35
mu/l
1.26
131
1005
35
201
1.75
2.52
1.2
1.1
0.42
3.56
u/ml
0.87
25
79
29
157
1.86
2.52
1.1
1.2
—
—
—
0
0
29
157
1.86
2.52
1.1
1.1
—
—
—
0
0
32
179
1.80
2.52
1.8
1.5
—
—
—
0
0
188
1504
1.28
2.51
3.7
1.8
—
—
—
0
0
1591
15299
1.18
2.51
26.2
15.7
13.58
13.36
%
8.95
1584
15106
17
75
2.28
2.51
2.2
1.9
81.12
97.36
ng/l
0.66
17
75
25
129
1.95
2.50
1.1
1.2
—
—
—
0
0
16
69
2.33
2.48
2.8
2.7
8.36
7.46
mmol/l
0.32
16
69
15
63
2.39
2.46
1.3
1.3
—
—
—
0
0
45
280
1.62
2.44
5.6
3.1
8.00
7.75
pmol/l
0.07
45
280
43
265
1.64
2.42
1.4
1.3
—
—
—
0
0
27
146
1.86
2.37
7.6
3.2
15.84
15.42
index
0.07
19
106
22
111
1.99
2.35
2.5
2.5
—
—
—
0
0
29
161
1.81
2.35
2.8
3.2
—
—
—
0
0
18
84
2.15
2.34
5.2
4.2
—
—
—
0
0
71
494
1.45
2.34
1.2
1.2
—
—
—
0
0
695
6322
1.15
2.33
2.2
2.0
—
—
—
0
0
92
672
1.39
2.32
1.3
1.1
1.53
0.96
u/ml
0.31
66
355
157
1243
1.28
2.30
2.3
2.4
24.91
21.44
au/ml
0.12
17
152
171
1371
1.27
2.27
1.7
1.5
18.59
21.93
iu/l
0.79
138
1107
65
448
1.47
2.26
2.4
1.7
3.58
3.62
mmol/l
0.15
60
425
14
60
2.34
2.21
1.2
1.3
28.64
28.55
s
0.02
14
60
148
1171
1.28
2.19
1.2
1.2
—
—
—
0
0
676
7380
0.87
2.17
3.0
2.7
—
—
—
0
0
28
158
1.78
2.17
3.0
2.6
0.95
1.75
g/24h
0.93
14
107
183
1488
1.25
2.16
3.5
1.8
—
—
—
0
0
146
1155
1.28
2.16
1.2
1.3
38.72
40.98
au/ml
—
6
80
7
19
3.69
2.15
1.6
1.8
—
—
—
0
0
84
1133
0.73
2.14
1.4
1.6
—
—
—
0
0
96
721
1.35
2.07
1.5
1.3
—
—
—
0
0
26
147
1.78
2.02
1.1
1.1
—
—
—
0
0
1620
15685
1.16
1.97
26.1
15.8
333.25
333.52
g/l
0.56
1609
15580
115
897
1.30
1.93
1.9
1.5
9.70
8.10
u/l
0.60
86
671
1675
16285
1.16
1.81
4.8
4.4
4.63
4.67
mmol/l
1.13
1587
15542
38
248
1.54
1.76
1.4
1.4
—
—
—
0
0
12
54
2.23
1.74
1.2
1.2
—
—
—
0
0
8
30
2.67
1.72
2.1
1.3
—
—
—
0
0
40
266
1.51
1.71
1.2
1.1
—
—
—
0
0
27
163
1.66
1.71
2.7
2.2
0.87
0.85
%
0.03
20
99
728
6753
1.12
1.70
2.1
1.9
1.42
1.36
mmol/l
0.82
631
5946
11
48
2.30
1.70
1.9
1.1
—
—
—
0
0
11
48
2.30
1.70
1.9
1.1
—
—
—
0
0
11
48
2.30
1.70
1.9
1.1
—
—
—
0
0
21
118
1.79
1.70
2.4
2.7
41.22
43.29
%
0.26
13
61
16
82
1.96
1.69
1.0
1.0
—
—
—
0
0
376
3346
1.15
1.69
1.7
1.6
—
—
—
0
0
33
211
1.57
1.68
2.0
1.7
286.40
284.84
mosm/kgh2o
0.15
25
147
180
1507
1.21
1.67
2.2
2.0
0.00
0.02
estimate
1.05
38
334
80
607
1.33
1.66
1.2
1.2
—
—
—
0
0
6
19
3.16
1.66
1.2
1.2
—
—
—
0
0
23
134
1.72
1.66
1.4
1.2
—
—
—
0
0
635
5855
1.12
1.64
1.6
1.6
—
—
—
0
0
122
982
1.26
1.63
2.9
2.3
8.28
8.14
ug/l
0.02
103
877
15
77
1.95
1.59
1.3
3.2
1.61
2.12
mmol/l
—
10
61
19
106
1.80
1.58
9.4
3.4
0.74
0.84
index
0.21
19
106
10
43
2.33
1.58
1.0
1.1
—
—
—
0
0
10
43
2.33
1.58
1.0
1.1
—
—
—
0
0
10
43
2.33
1.58
1.0
1.1
—
—
—
0
0
24
144
1.67
1.57
1.5
1.1
—
—
—
0
0
20
114
1.76
1.56
1.1
1.1
—
—
—
0
0
16
85
1.89
1.55
1.1
1.4
141.44
141.23
nmol/l
0.01
16
85
55
747
0.73
1.53
1.6
1.6
—
—
—
0
0
183
1556
1.19
1.47
1.3
1.2
153.90
139.07
u/ml
0.17
63
606
5
16
3.13
1.44
1.0
1.1
—
—
—
0
0
60
449
1.35
1.41
2.7
2.8
7.72
6.28
umol/l
0.23
46
340
72
554
1.31
1.40
1.2
1.1
4.99
4.84
u/ml
0.03
57
312
7
29
2.42
1.39
1.1
1.0
—
—
—
0
0
7
29
2.42
1.39
3.6
4.6
—
—
—
0
0
34
230
1.49
1.39
2.3
4.1
71.67
335.68
u/ml
1.24
29
215
9
41
2.20
1.37
2.6
2.3
—
—
—
0
0
6
23
2.61
1.36
2.0
5.5
42.50
44.47
umol/l
—
6
17
15
82
1.84
1.35
1.1
1.1
—
—
—
0
0
96
773
1.25
1.33
2.6
2.1
0.00
0.98
estimate
0.50
21
257
6
24
2.50
1.30
2.5
2.9
—
—
—
0
0
1677
16398
1.13
1.29
5.1
4.8
2.74
2.78
mmol/l
0.97
1583
15586
67
519
1.30
1.27
1.2
1.1
12.03
5.79
u/ml
1.40
51
271
8
35
2.29
1.27
1.3
1.2
—
—
—
0
0
6
25
2.40
1.24
2.3
1.2
—
—
—
0
0
1658
16211
1.12
1.24
4.6
4.3
1.43
1.45
mmol/l
1.36
1564
15395
225
1977
1.15
1.24
1.3
1.2
—
—
—
0
0
56
729
0.76
1.22
1.5
1.5
—
—
—
0
0
11
56
1.97
1.22
2.5
1.9
—
—
—
0
0
38
271
1.41
1.21
2.6
2.5
177.71
88.42
ug/min
0.25
26
174
55
717
0.76
1.21
1.5
1.5
1.21
1.26
mm
0.36
41
524
33
230
1.44
1.19
3.4
1.9
—
—
—
0
0
18
110
1.64
1.15
1.6
1.6
0.60
2.84
u/ml
1.86
18
110
8
39
2.05
1.15
1.9
1.7
—
—
—
0
0
5
20
2.50
1.15
1.0
1.2
—
—
—
0
0
20
126
1.59
1.14
1.1
1.1
1693.50
1551.17
miu/ml
0.20
20
126
23
150
1.54
1.14
4.3
2.5
1.46
0.28
mmol/l
0.89
18
142
32
225
1.43
1.12
4.4
2.3
—
—
—
0
0
46
345
1.34
1.11
1.4
1.1
315591.14
1533.68
iu/ml
—
7
88
7
32
2.19
1.08
1.4
1.3
35.37
53.81
%
—
7
27
32
227
1.42
1.08
1.1
1.1
12.15
5.37
iu/ml
—
6
52
81
659
1.24
1.07
1.9
1.7
—
—
—
0
0
23
154
1.50
1.03
1.0
1.0
—
—
—
0
0
5
22
2.28
1.03
1.8
2.7
104.20
97.23
g/l
—
5
22
5
22
2.28
1.03
1.0
1.2
—
—
—
0
0
31
221
1.41
1.02
1.1
1.2
—
—
—
0
0
9
47
1.92
1.02
2.2
1.2
—
—
—
0
0
12
68
1.77
1.00
2.2
2.4
16.90
18.10
umol/l
0.11
12
68
157
1369
1.16
0.99
2.3
2.2
6.26
6.15
ph
0.76
108
892
1565
15316
1.09
0.96
4.1
3.7
1.31
1.26
mmol/l
2.19
1473
14474
11
62
1.78
0.94
1.1
1.3
80.27
69.53
ug/l
0.19
11
62
12
70
1.72
0.92
1.1
1.1
—
351.21
—
0
14
1117
10797
1.08
0.91
3.8
3.4
—
27469.07
—
0
15
216
2396
0.89
0.89
3.0
2.9
0.63
0.72
ug/l
1.11
118
1357
6
29
2.07
0.89
1.8
2.1
—
—
—
0
0
61
493
1.24
0.89
1.1
1.1
0.91
0.82
u/ml
0.06
40
195
58
466
1.25
0.89
1.1
1.1
7.95
20.21
au/ml
1.36
15
109
113
971
1.17
0.88
1.3
1.3
192.97
226.05
miu/ml
0.65
60
502
189
1687
1.13
0.88
3.6
4.1
31.25
31.75
%
0.24
125
1206
6
31
1.94
0.84
1.5
1.5
130.62
51.52
mu/l
—
6
26
8
45
1.78
0.84
1.4
2.6
1.18
1.19
umol/l
—
8
34
73
607
1.21
0.83
1.1
1.1
10.49
5.72
eliau/ml
—
7
94
10
165
0.60
0.81
1.7
1.6
0.64
0.49
e9/l
—
10
165
133
1167
1.15
0.81
4.5
3.6
4.63
4.68
pmol/l
0.22
124
1060
0
24
0.00
0.79
0.0
1.0
—
6.82
—
0
24
188
1691
1.12
0.79
2.2
2.3
11.79
12.89
nmol/l
1.07
171
1564
77
908
0.84
0.77
1.0
1.1
0.72
0.64
ratio
—
5
88
29
218
1.33
0.75
1.3
1.4
0.58
0.59
nmol/l
0.14
29
210
10
60
1.67
0.72
3.4
2.7
121.30
89.96
ug/l
—
10
60
82
955
0.85
0.72
1.5
1.5
63.88
59.50
ug/l
0.42
69
813
110
963
1.15
0.71
2.5
1.9
—
—
—
0
0
57
472
1.21
0.70
9.3
8.6
—
—
—
0
0
26
195
1.34
0.69
2.5
4.6
38.14
102.48
u/ml
—
7
58
7
42
1.67
0.68
2.4
2.9
0.59
0.61
mmol/l
—
7
42
9
59
1.53
0.68
1.0
1.4
21.70
16.48
umol/l
—
9
50
49
402
1.22
0.67
3.8
2.1
0.63
0.81
nmol/l
1.13
41
350
7
43
1.63
0.66
3.7
1.8
42.37
41.67
g/l
—
7
43
5
30
1.67
0.61
1.0
1.0
—
—
—
0
0
5
30
1.67
0.61
1.4
1.3
52.80
66.20
ug/l
—
5
30
10
152
0.66
0.61
1.0
1.3
171.23
165.03
pmol/l
—
10
152
21
156
1.35
0.61
1.4
1.7
11.80
11.56
umol/l
0.06
21
144
0
20
0.00
0.60
0.0
1.2
—
43.13
—
0
8
0
20
0.00
0.60
0.0
1.0
—
167.65
—
0
20
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
22
165
1.34
0.60
2.4
2.5
30.68
32.53
pg
0.94
22
165
12
80
1.50
0.59
1.1
1.3
—
—
—
0
0
28
355
0.79
0.59
2.3
1.9
—
—
—
0
0
64
548
1.17
0.58
2.4
2.2
6.19
4.29
iu/l
0.21
29
242
25
193
1.30
0.57
1.2
1.2
29.40
37.93
mg/l
0.95
19
150
8
125
0.64
0.54
1.4
1.2
11.25
8.06
mm/h
—
8
125
19
142
1.34
0.54
1.4
1.4
1.67
1.83
mmol/l
0.97
19
131
14
99
1.42
0.54
1.6
1.6
—
—
—
0
0
17
125
1.36
0.53
1.2
1.2
—
—
—
0
0
18
134
1.35
0.53
1.3
1.6
—
—
—
0
0
15
109
1.38
0.51
1.3
1.3
—
—
—
0
0
89
989
0.90
0.45
1.1
1.1
—
—
—
0
0
7
50
1.40
0.45
1.7
6.2
5.96
5.13
kpa
—
7
50
22
175
1.26
0.43
4.5
3.5
—
—
—
0
0
20
158
1.27
0.41
1.8
2.2
—
—
—
0
0
77
691
1.12
0.40
1.6
1.7
18.04
10.06
u/ml
0.81
21
183
31
259
1.20
0.40
1.1
1.3
107.05
28.82
u/l
0.49
26
224
31
367
0.84
0.39
1.1
1.1
3.38
2.10
eliau/ml
0.30
12
171
5
36
1.39
0.38
1.4
2.0
—
—
—
0
0
37
317
1.17
0.38
3.2
3.2
32.96
24.58
mg/l
0.48
27
202
12
89
1.35
0.38
2.5
2.0
—
—
—
0
0
9
68
1.32
0.37
2.8
2.5
—
—
—
0
0
406
3906
1.05
0.37
4.1
4.7
2.19
2.08
ug/l
0.16
367
3578
91
830
1.10
0.37
1.1
1.1
—
—
—
0
0
55
489
1.13
0.35
1.3
1.1
—
—
—
0
0
6
43
1.40
0.35
1.0
1.3
10.99
11.55
mmol/l
—
6
43
51
452
1.13
0.34
1.5
1.5
0.36
0.35
nmol/l
0.04
41
361
55
490
1.13
0.34
1.3
1.1
—
—
—
0
0
19
154
1.24
0.34
1.5
1.3
0.49
0.62
ratio
1.19
11
81
25
295
0.85
0.32
1.3
1.6
—
—
—
0
0
13
101
1.29
0.31
1.1
1.0
15.90
16.94
u/ml
—
7
70
24
202
1.19
0.31
2.7
2.1
—
—
—
0
0
23
193
1.19
0.30
1.4
1.4
0.18
0.27
nmol/l
0.48
17
153
7
55
1.27
0.30
1.3
1.5
85.71
89.04
nmol/24h
—
7
55
17
139
1.22
0.29
3.2
2.2
26.92
32.38
mg/l
0.28
12
94
12
95
1.26
0.26
1.3
1.3
—
—
—
0
0
21
179
1.17
0.25
1.0
1.1
—
—
—
0
0
9
77
1.17
0.24
2.8
2.4
—
—
—
0
0
167
1749
0.95
0.24
1.6
1.6
901.34
985.57
mu/l
0.74
144
1513
39
350
1.12
0.24
1.6
1.4
15.24
20.08
u/l
0.60
31
293
10
78
1.28
0.24
1.3
1.2
—
—
—
0
0
6
84
0.71
0.24
1.0
1.5
180.17
159.58
mmol/24h
—
6
84
14
115
1.22
0.23
2.6
1.4
71.36
75.11
umol/l
0.27
14
115
185
1930
0.95
0.23
1.5
1.4
—
—
—
0
0
43
472
0.91
0.22
1.6
1.4
3.29
3.93
ug/l
0.23
37
439
0
10
0.00
0.21
0.0
1.6
—
5.31
—
0
10
0
11
0.00
0.21
0.0
1.1
—
6.33
—
0
6
0
11
0.00
0.21
0.0
1.1
—
51.17
—
0
6
0
13
0.00
0.21
0.0
3.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
38
413
0.92
0.17
1.1
1.1
—
—
—
0
0
5
70
0.71
0.16
5.2
6.0
8.00
8.27
%
—
5
70
5
70
0.71
0.16
2.6
3.0
55.80
43.70
%
—
5
70
9
78
1.15
0.15
2.8
3.3
—
—
—
0
0
9
79
1.14
0.15
1.3
1.6
1.00
3.77
u/field
—
9
65
116
1118
1.04
0.13
1.6
1.5
—
—
—
0
0
9
109
0.82
0.13
2.2
2.7
—
—
—
0
0
39
415
0.94
0.11
2.3
2.4
—
—
—
0
0
31
330
0.94
0.09
1.3
1.1
—
—
—
0
0
16
145
1.10
0.09
1.6
1.1
—
—
—
0
0
21
225
0.93
0.07
1.0
1.1
13.39
14.83
u/ml
—
8
86
7
80
0.87
0.07
1.0
1.0
59.19
38.09
iu/ml
—
7
80
12
132
0.91
0.06
1.0
1.0
—
—
—
0
0
10
91
1.10
0.04
4.1
2.4
44.90
50.10
umol/l
—
10
82
20
190
1.05
0.04
1.3
1.4
—
—
nmol/l
—
0
0
24
231
1.04
0.02
1.5
1.6
7.46
7.62
mmol/l
0.13
24
224
12
126
0.95
0.00
1.3
1.0
—
—
—
0
0
38
379
1.00
0.00
1.2
1.3
—
—
—
0
0
22
223
0.99
0.00
1.4
1.2
—
—
—
0
0
33
327
1.01
0.00
1.8
1.6
537.79
361.49
mu/l
0.75
28
267
37
375
0.99
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
12.9
—
91.00
—
0
7
7
71
0.99
-0.00
1.7
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.3
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
1302.14
—
0
7
5
53
0.94
-0.00
2.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
1.90
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_IMPETIGO and mortality.

Females

Parameter HR [95% CI] p-value
L12_IMPETIGO 2.412 [1.88, 3.09] < 0.001
Birth year 0.995 [0.98, 1.0] 0.296

During the follow-up period (1.1.1998 — 31.12.2019), 434 out of 8762 females with L12_IMPETIGO died.

Males

Parameter HR [95% CI] p-value
L12_IMPETIGO 2.621 [2.05, 3.35] < 0.001
Birth year 0.991 [0.98, 1.0] 0.068

During the follow-up period (1.1.1998 — 31.12.2019), 538 out of 9066 males with L12_IMPETIGO died.

Mortality risk

Mortality risk for people of age

years, who have L12_IMPETIGO.

N-year risk Females Males
1 0.191% 0.601%
5 1.282% 3.415%
10 3.315% 8.425%
15 6.262% 15.572%
20 11.018% 26.219%

Relationships between endpoints

Index endpoint: L12_IMPETIGO – Impetigo

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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