This is a non-core endpoint: only basic statistics are computed.
Toxic effect of other gases, fumes and vapours
ST19_TOXIC_EFFECT_OTHER_GASES_FUMES_VAPOU
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
247 |
4. Check minimum number of eventsNone |
247 |
5. Include endpointsNone |
247 |
6. Filter based on genotype QC (FinnGen only) |
221 |
Control definitions (FinnGen only)
- Control exclude
- ST19_TOXIC_EFFEC_SUBST_CHIEF_NONME_SOURCE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T5[1-9]|T6[0-5]
- Name in latin
- Effectus toxicus aliorum gasorum, fumorum et vaporum
Similar endpoints
↥List of similar endpoints to
Toxic effect of other gases, fumes and vapours
based on the number of shared cases.
Similar with more cases:
- Toxic effects of substances chiefly nonmedicinal as to source
- Injury, poisoning and certain other consequences of external causes
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 221 | 89 | 132 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 46.33 | 45.07 | 47.19 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 230
- Matched controls
- 2300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T59.8
ICD-10 Finland
Toxic effect: Other specified gases, fumes and vapours
876.9
112.0
101
*
T59.9
ICD-10 Finland
Toxic effect: Gases, fumes and vapours, unspecified
+∞
49.8
46
*
T59.7
ICD-10 Finland
Toxic effect: Carbon dioxide
+∞
36.4
34
*
X09
ICD-10 Finland
Exposure to unspecified smoke, fire and flames
184.9
31.5
32
*
X47
ICD-10 Finland
Accidental poisoning by and exposure to carbon monoxide and other gases and vapours
+∞
24.4
23
*
T59.4
ICD-10 Finland
Toxic effect: Chlorine gas
+∞
16.9
16
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.0
16.2
26
41
T59.0
ICD-10 Finland
Toxic effect: Nitrogen oxides
+∞
14.7
14
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
12.9
54
188
X00
ICD-10 Finland
Exposure to uncontrolled fire in building or structure
137.2
12.6
13
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.3
11.3
23
27
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
63.0
10.7
12
*
J96.1
ICD-10 Finland
Chronic respiratory failure
15.2
10.7
17
12
R06.0
ICD-10 Finland
Dyspnoea
2.6
9.9
77
374
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.7
9.7
33
99
N05AH04
ATC
quetiapine; oral
2.7
9.7
63
279
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
9.4
119
717
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
14.5
9.3
15
11
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
9.3
51
206
N02BF02
ATC
pregabalin; oral
3.8
8.4
27
78
M01AE03
ATC
ketoprofen; systemic, rectal
2.3
8.3
90
502
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.7
8.2
28
84
AA1AD
NOMESCO Finland
CT of head and brain
2.4
7.9
73
378
IHZ05, ,
SPAT
4.3
7.8
21
53
P29
ICPC
Psychological sympt/compl other
3.2
7.6
32
110
N07BB01
ATC
disulfiram; oral
4.0
7.6
22
59
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.1
7.5
16
21
N05CF01
ATC
zopiclone; oral
2.2
7.4
82
457
T59.5
ICD-10 Finland
Toxic effect: Fluorine gas and hydrogen fluoride
+∞
7.3
7
*
T58
ICD-10 Finland
Toxic effect of carbon monoxide
+∞
7.3
7
*
K04.1
ICD-10 Finland
Necrosis of pulp
2.9
7.2
37
143
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
31.1
7.2
9
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.2
7.0
75
411
N05BA01
ATC
diazepam; systemic, rectal
2.7
6.9
41
172
X59
ICD-10 Finland
Exposure to unspecified factor
2.3
6.8
59
296
N05AA02
ATC
levomepromazine; systemic
4.0
6.5
19
51
N06AB04
ATC
citalopram; systemic
2.4
6.4
53
259
E86
ICD-10 Finland
Volume depletion
11.5
6.4
11
10
R03BB04
ATC
tiotropium bromide; inhalant
3.2
6.2
25
84
I50.9
ICD-10 Finland
Heart failure, unspecified
2.7
6.2
36
149
J96.0
ICD-10 Finland
Acute respiratory failure
13.0
6.1
10
8
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
13.0
6.1
10
8
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
6.3
6.1
15
25
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
10.4
6.1
11
11
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
6.0
65
354
N05CD07
ATC
temazepam; oral
2.9
6.0
30
114
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
105
3.50
8.91
2.9
2.7
1.78
1.28
%
1.20
33
105
114
692
2.28
8.63
7.0
3.5
25.94
41.27
ng/l
1.34
80
479
45
187
2.75
7.69
5.5
3.5
6.29
5.71
kpa
1.42
45
181
38
160
2.65
6.29
5.5
3.0
5.02
4.48
kpa
0.87
38
154
43
194
2.50
6.18
7.7
13.6
1.47
1.00
mmol/l
0.30
35
162
29
110
2.87
5.83
4.0
11.4
25.23
24.56
mmol/l
0.52
29
103
25
87
3.10
5.83
2.6
10.2
2.41
1.51
%
2.53
25
78
28
106
2.87
5.65
5.6
2.9
24.06
24.45
mmol/l
0.28
28
106
42
199
2.36
5.41
7.8
13.3
5.44
5.10
kpa
0.88
42
189
42
199
2.36
5.41
7.9
13.3
12.94
12.23
kpa
0.19
42
191
38
174
2.42
5.27
7.9
14.7
132.26
124.56
g/l
1.24
38
169
27
106
2.75
5.10
3.3
2.7
0.59
0.64
%
0.29
27
106
15
46
3.42
4.27
3.6
4.6
26.27
36.46
umol/l
2.27
15
41
87
589
1.77
4.04
4.1
2.1
181.06
268.24
u/l
1.04
80
566
52
301
1.94
3.97
3.2
1.9
—
—
—
0
0
26
114
2.44
3.95
6.6
3.1
3.86
1.58
mmol/l
1.11
21
88
54
319
1.91
3.88
2.3
2.1
1.58
1.45
%
0.57
48
284
132
1019
1.69
3.72
8.5
6.7
10.15
11.86
umol/l
1.89
126
977
174
1453
1.81
3.66
9.9
7.9
77.94
78.56
u/l
0.08
165
1387
40
221
1.98
3.47
3.0
1.7
—
—
—
0
0
54
334
1.81
3.33
4.6
3.6
335.28
291.92
ng/l
0.08
38
241
45
263
1.88
3.32
2.7
2.3
30.01
29.64
s
0.16
45
258
38
210
1.97
3.30
3.1
1.8
—
—
—
0
0
105
787
1.61
3.15
9.4
7.4
1.19
1.21
mmol/l
2.03
100
741
5
5
10.18
2.99
2.0
2.0
—
—
—
0
0
113
876
1.57
2.86
11.2
8.1
1.20
1.21
mmol/l
0.99
102
775
22
105
2.21
2.79
3.2
1.6
—
—
—
0
0
14
55
2.65
2.67
2.1
2.8
—
—
—
0
0
133
1087
1.53
2.55
10.2
10.8
4.25
4.12
e9/l
0.28
120
946
21
103
2.14
2.51
10.6
17.9
17.46
16.37
%
0.69
21
98
93
711
1.52
2.40
4.5
3.0
28.26
30.70
u/l
0.75
88
673
8
22
3.73
2.38
3.0
1.4
—
—
—
0
0
5
8
6.36
2.38
2.6
8.9
—
—
—
0
0
37
226
1.76
2.36
4.0
3.0
4.70
7.17
umol/l
1.84
31
205
23
120
2.02
2.35
2.1
1.6
0.17
0.31
mg/l
1.26
12
49
70
512
1.53
2.19
4.9
3.8
1568.28
1192.09
ng/l
0.41
61
434
13
55
2.45
2.16
1.5
1.3
—
—
—
0
0
41
266
1.66
2.12
2.0
1.7
1295.08
1136.16
nmol/l
0.42
29
212
6
15
4.08
2.05
1.0
1.1
—
—
—
0
0
164
1435
1.50
2.03
4.6
4.1
14.63
14.71
pmol/l
0.15
151
1325
19
98
2.02
2.02
2.3
1.3
—
—
—
0
0
28
166
1.78
1.98
11.6
7.4
11.29
8.24
mmol/l
0.92
28
161
61
442
1.52
1.98
4.4
3.5
1.02
1.02
kg/l
0.19
37
284
7
21
3.40
1.98
3.4
4.0
—
—
—
0
0
58
416
1.53
1.97
2.4
1.8
1.11
1.32
mg/l
0.22
39
332
15
71
2.19
1.97
9.1
3.2
26.67
25.10
mmol/l
0.53
15
66
10
39
2.63
1.96
1.0
1.1
1.04
1.07
eliau/ml
—
5
16
208
1929
1.82
1.94
27.2
14.4
22.44
24.25
mg/l
0.40
175
1563
32
202
1.68
1.83
2.2
2.2
324.88
397.37
nmol/l
1.45
32
191
26
158
1.73
1.71
3.0
2.5
—
—
—
0
0
29
182
1.68
1.70
5.0
3.0
—
—
—
0
0
157
1385
1.42
1.68
4.6
3.3
—
—
—
0
0
11
49
2.31
1.66
1.6
1.4
—
—
—
0
0
14
70
2.06
1.63
1.7
1.7
27.12
5.33
u/ml
—
6
18
5
15
3.38
1.53
1.0
1.0
—
—
—
0
0
13
65
2.06
1.52
3.5
1.8
—
—
—
0
0
94
773
1.37
1.49
2.4
2.0
95.87
94.55
pmol/l
0.11
57
398
9
38
2.42
1.47
1.8
1.8
—
—
—
0
0
69
541
1.39
1.46
4.8
3.6
0.00
0.00
estimate
-0.00
24
194
67
525
1.39
1.42
4.2
2.8
0.58
0.31
e6/l
0.39
51
369
7
29
2.46
1.40
1.9
1.4
—
—
—
0
0
6
23
2.65
1.37
7.7
3.0
1.17
1.18
mmol/l
—
6
23
6
23
2.65
1.37
7.7
3.0
104.17
107.00
mmol/l
—
6
23
13
68
1.97
1.36
3.6
2.0
—
—
—
0
0
41
296
1.47
1.35
4.4
2.7
3.26
2.45
e6/l
0.17
20
139
40
288
1.47
1.34
2.2
2.2
—
—
—
0
0
6
25
2.44
1.25
1.0
1.2
—
—
—
0
0
21
133
1.64
1.22
1.7
1.5
—
—
—
0
0
187
1737
1.41
1.22
5.9
4.9
1.72
1.88
mu/l
1.21
177
1614
61
484
1.35
1.18
4.0
2.8
350.15
355.68
umol/l
0.14
54
429
43
322
1.41
1.18
3.9
2.6
0.22
0.73
e6/l
3.70
23
163
72
588
1.33
1.15
3.0
3.3
2.36
2.36
mmol/l
0.14
64
543
7
31
2.30
1.11
2.1
1.6
—
—
—
0
0
7
32
2.22
1.09
2.1
1.4
—
—
—
0
0
10
52
1.97
1.08
1.3
1.4
—
—
—
0
0
35
464
0.71
1.06
2.5
2.7
0.55
0.72
ug/l
0.51
16
255
18
271
0.64
1.04
2.2
2.0
4.58
3.63
ratio
0.91
12
215
5
22
2.30
1.04
1.6
1.1
119.74
159.81
pmol/l
—
5
22
7
34
2.09
1.03
1.0
1.1
—
—
—
0
0
7
34
2.09
1.03
1.7
1.4
—
—
—
0
0
7
34
2.09
1.03
1.3
1.4
—
—
—
0
0
61
494
1.32
1.03
2.0
1.6
18.81
21.21
nmol/l
0.56
56
432
13
77
1.73
0.97
1.3
1.3
—
—
—
0
0
20
134
1.54
0.95
2.9
2.3
—
—
—
0
0
115
1019
1.26
0.95
4.7
3.5
0.00
0.00
estimate
-0.00
26
211
116
1029
1.26
0.95
4.7
3.6
0.00
7.77
estimate
0.50
26
209
194
1834
1.37
0.95
21.5
13.2
88.61
86.22
ml/min/173m2
0.75
182
1672
154
1416
1.27
0.90
5.5
4.0
10.75
10.09
mm/h
0.19
144
1329
20
136
1.52
0.90
1.5
1.2
121.48
122.22
u/ml
—
9
46
69
579
1.27
0.89
3.9
4.1
9.41
10.58
mg/mmol
0.09
42
383
28
205
1.42
0.88
5.5
7.4
—
—
—
0
0
8
43
1.89
0.88
3.0
1.4
—
—
—
0
0
8
44
1.85
0.87
2.6
1.8
—
—
—
0
0
180
1692
1.29
0.85
27.2
17.7
334.06
334.16
g/l
0.04
180
1686
13
200
0.63
0.84
1.6
1.7
3.58
3.59
mmol/l
—
6
142
116
1040
1.23
0.83
4.7
3.6
0.00
0.00
estimate
-0.00
26
197
191
1812
1.32
0.82
5.1
4.6
6.05
5.93
mmol/l
0.43
179
1684
37
289
1.33
0.81
4.2
2.0
2.42
2.32
g/l
0.48
32
270
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
188
1785
1.29
0.76
6.3
5.8
38.77
39.01
mmol/mol
0.13
179
1700
5
24
2.11
0.75
1.0
1.1
—
—
—
0
0
5
24
2.11
0.75
1.2
1.3
—
—
—
0
0
5
25
2.02
0.73
1.0
1.1
—
—
—
0
0
7
40
1.77
0.72
2.0
1.3
—
—
—
0
0
43
350
1.28
0.71
2.0
1.7
507.32
37261596.67
pmol/l
0.50
37
314
33
261
1.31
0.67
4.7
2.0
20.97
23.99
%
0.63
27
250
88
784
1.20
0.64
4.6
3.4
0.00
0.00
estimate
-0.00
20
184
55
468
1.23
0.63
3.2
2.1
3.25
2.81
mg/l
0.88
48
415
95
854
1.19
0.62
3.3
2.8
—
—
estimate
—
0
0
51
597
0.81
0.62
3.4
3.8
16.44
21.78
%
1.24
13
239
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
18.19
—
0
8
9
59
1.55
0.55
1.0
1.1
—
—
—
0
0
9
60
1.52
0.55
1.0
1.1
—
—
—
0
0
52
447
1.21
0.54
1.8
1.7
—
—
—
0
0
17
126
1.38
0.53
2.2
2.0
34.82
36.71
nmol/l
0.15
17
121
38
320
1.22
0.49
2.4
2.3
—
—
—
0
0
7
51
1.38
0.44
2.3
1.5
—
—
—
0
0
5
32
1.57
0.42
2.0
1.6
—
—
—
0
0
8
58
1.39
0.42
2.6
1.6
—
—
—
0
0
5
33
1.53
0.41
1.6
1.6
43.78
55.38
ug/l
—
5
33
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
14
106
1.34
0.40
1.2
1.3
—
—
—
0
0
5
36
1.40
0.38
2.2
1.5
—
—
—
0
0
8
112
0.70
0.38
1.1
1.0
—
—
—
0
0
41
358
1.18
0.37
1.3
1.3
23.53
30.46
iu/ml
0.30
14
112
87
804
1.13
0.37
3.4
2.5
78.69
74.53
nmol/l
0.53
82
746
6
41
1.48
0.36
2.0
1.5
—
—
—
0
0
6
42
1.44
0.36
2.0
1.8
—
—
—
0
0
64
582
1.14
0.35
4.0
3.0
0.00
0.00
estimate
-0.00
21
168
17
138
1.25
0.31
1.6
3.4
64.75
67.44
g/l
0.58
17
131
13
102
1.29
0.30
2.1
2.1
196.92
236.78
pmol/l
0.76
13
96
8
63
1.28
0.28
2.5
1.7
—
—
—
0
0
16
132
1.23
0.26
1.9
2.8
68.14
68.61
ml/min/173m2
—
7
62
5
75
0.66
0.26
1.6
1.3
—
—
—
0
0
75
799
0.91
0.25
2.0
1.9
1.75
1.43
mmol/l
1.09
66
684
5
38
1.32
0.23
2.0
1.6
—
—
—
0
0
12
97
1.25
0.23
2.1
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
15.99
—
0
11
0
10
0.00
0.21
0.0
3.6
—
200.70
—
0
10
0
10
0.00
0.21
0.0
1.1
—
99.00
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.9
—
187.90
—
0
10
0
13
0.00
0.21
0.0
5.9
—
132.28
—
0
13
53
493
1.10
0.20
1.4
1.3
0.84
1.18
u/ml
0.75
14
141
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
193
1897
1.11
0.19
5.1
4.7
4.67
4.61
mmol/l
0.39
181
1794
7
58
1.21
0.18
3.9
2.5
212.57
187.00
%
—
7
58
7
58
1.21
0.18
1.3
2.6
9.40
10.77
g/l
—
7
53
47
438
1.09
0.17
3.5
2.3
—
—
—
0
0
5
66
0.75
0.17
1.4
1.3
—
—
—
0
0
184
1810
1.08
0.15
4.4
4.0
1.48
1.32
mmol/l
1.44
173
1691
192
1893
1.09
0.14
5.1
4.7
1.38
1.39
mmol/l
0.19
181
1781
5
47
1.07
0.09
1.4
2.9
0.00
0.00
g/l
—
5
47
10
88
1.14
0.08
1.1
2.2
44.20
40.02
u/l
—
10
79
22
233
0.94
0.06
2.4
1.5
—
—
—
0
0
21
222
0.94
0.05
5.0
4.4
29.67
30.71
%
0.16
15
143
76
773
0.97
0.04
3.8
4.2
1.29
1.63
ug/l
0.96
68
698
193
1919
1.04
0.03
5.6
5.3
2.78
2.74
mmol/l
0.21
184
1810
33
322
1.03
0.02
1.2
1.3
20.21
8.28
u/ml
0.27
18
125
16
165
0.97
0.00
1.6
1.4
—
—
—
0
0
7
77
0.91
0.00
2.4
1.6
16.18
5.05
mg/l
—
7
57
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
81.96
—
0
7
9
92
0.98
-0.00
1.1
1.1
0.94
0.91
g/l
—
9
92
0
5
0.00
-0.00
0.0
12.2
—
5.96
—
0
5
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
42.60
—
0
9
9
90
1.00
-0.00
1.1
1.1
1.48
1.52
g/l
—
9
90
6
69
0.87
-0.00
4.0
2.3
89.50
94.96
%
—
6
69
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
79.73
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
2.4
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: ST19_TOXIC_EFFECT_OTHER_GASES_FUMES_VAPOU – Toxic effect of other gases, fumes and vapours
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).