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Other retinal artery occlusion

DOID EFO Endpoint Browser PheWeb

H7_OTHRETARTOCC

retinal artery occlusion: Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H34.2
  • Hospital discharge: ICD-9 — 3623B
  • Hospital discharge: ICD-8 — 37703
  • Cause of death: ICD-10 — H34.2
  • Cause of death: ICD-9 — 3623B
  • Cause of death: ICD-8 — 37703

2 out of 7 registries used, show all original rules.

991

4. Check minimum number of events

None

991

5. Include endpoints

None

991

6. Filter based on genotype QC (FinnGen only)

882

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H34
Name in latin
Aliae occlusiones arteriales retinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6560 2771 3720
Only index persons 5215 2234 2981
Unadjusted period prevalence (%)
Whole population 0.09 0.08 0.10
Only index persons 0.10 0.08 0.11
Median age at first event (years)
Whole population 68.13 69.45 67.22
Only index persons 68.45 69.76 67.47

-FinnGen-

Key figures

All Female Male
Number of individuals 882 346 536
Unadjusted period prevalence (%) 0.20 0.12 0.25
Median age at first event (years) 68.41 67.76 68.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
920
Matched controls
9200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H34.2
ICD-10 Finland
Other retinal artery occlusions
4503599627370496.0
307.7
853
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
725.6
185.6
177
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
100.9
175.3
91
10
CKC12
NOMESCO Finland
Photocoagulation of retina
93.6
162.2
85
10
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
9.2
151.2
210
288
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
10.9
131.8
153
165
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.6
131.1
215
354
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
126.0
118
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
11.7
114.1
124
121
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
7.2
102.3
171
284
H43.1
ICD-10 Finland
Vitreous haemorrhage
21.7
97.7
74
37
H53.4
ICD-10 Finland
Visual field defects
13.1
94.9
94
79
XCK10
NOMESCO Finland
Photography of fundus of eye
5.7
90.0
195
415
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
8.0
84.1
122
172
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
12.1
80.7
84
76
XCK00
NOMESCO Finland
Perimetry
6.3
79.7
148
271
B01AC04
ATC
clopidogrel; oral
3.7
78.4
357
1331
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
77.7
274
856
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
5.1
75.6
183
426
AA1AD
NOMESCO Finland
CT of head and brain
3.2
63.8
466
2261
H53.1
ICD-10 Finland
Subjective visual disturbances
5.4
62.1
134
280
G45.3
ICD-10 Finland
Amaurosis fugax
9.4
62.0
77
89
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
12.9
56.9
56
46
PA6AD
NOMESCO Finland
CT of neck arteries
6.2
55.8
102
182
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
17.7
53.4
44
26
C10AA05
ATC
atorvastatin; oral
2.9
51.7
566
3299
37703
ICD-8 Finland
Other diseases of retina and optic nerve, Thrombosis venae centralis retinae
+∞
51.5
49
*
H53.9
ICD-10 Finland
Visual disturbance, unspecified
6.8
50.4
83
133
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
59.9
43.8
51
9
XCD20
NOMESCO Finland
Photoangiography of eye
70.6
41.4
47
7
WX140
NOMESCO Finland
Parabulbar anesthesy
6.6
39.4
65
104
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.8
34.9
207
851
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
31.4
30
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.5
30.5
114
356
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
42.8
30.1
37
9
XCH00
NOMESCO Finland
Eye pressure measurement
4.4
28.0
73
176
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
27.6
545
3710
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
30.3
26.5
35
12
CS494
NOMESCO Finland
Other visual field testing
5.3
23.8
49
97
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.5
23.5
181
834
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
23.3
339
2023
H3601, E113,
ICD-10 Finland
+∞
23.0
22
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
+∞
23.0
22
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
85.7
22.8
25
*
H33.3
ICD-10 Finland
Retinal breaks without detachment
123.1
22.7
24
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.2
22.0
91
302
H3600, E113,
ICD-10 Finland
+∞
22.0
21
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
21.8
160
720
C08CA01
ATC
amlodipine; oral
2.0
21.6
450
3026
C10AX09
ATC
ezetimibe; oral
2.3
21.4
205
1035
H53.8
ICD-10 Finland
Other visual disturbances
7.4
21.3
31
43
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.1
21.2
283
1627
C10AA01
ATC
simvastatin; oral
1.9
20.9
508
3582
3623B
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO RAMI ARTERIAE CENTRALIS RETINAE]
+∞
20.9
20
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.4
20.8
157
714
H25.1
ICD-10 Finland
Senile nuclear cataract
2.0
20.7
362
2285
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.7
20.7
69
199
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.6
20.7
139
599
F05
ICPC
Visual disturbance other
4.5
20.6
51
118
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
20.6
343
2130
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
7.6
20.5
29
39
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
16.5
20.2
32
20
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
16.5
20.2
32
20
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
19.8
667
5208
CKD40
NOMESCO Finland
Endophotocoagulation of retina
107.4
19.6
21
*
C01DA14
ATC
isosorbide mononitrate; oral
2.1
19.6
250
1408
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
18.9
399
2661
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
18.8
18
*
H34.0
ICD-10 Finland
Transient retinal artery occlusion
+∞
18.8
18
*
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
18.8
18
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.5
18.5
123
526
S01ED51
ATC
timolol, combinations; ophthalmic
2.7
18.3
107
429
Z3231
NOMESCO Finland
Registered nurse
1.9
18.1
288
1746
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.0
17.8
51
132
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
17.8
224
1249
T90
ICPC
Diabetes non-insulin dependent
1.9
17.5
276
1664
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
17.4
267
1594
S01EC01
ATC
acetazolamide; systemic
4.8
17.2
39
84
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.7
16.9
40
89
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
16.9
291
1804
A10AE04
ATC
insulin glargine; parenteral
2.5
16.8
113
485
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
64.6
16.8
19
*
H33.5
ICD-10 Finland
Other retinal detachments
35.8
16.7
21
6
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
16.7
234
1353
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
16.6
306
1937
ZXA10
NOMESCO Finland
Bilateral
2.0
15.9
199
1104
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.2
15.7
64
210
114
Kela drug reimbursment
Glaucoma
2.3
15.4
123
570
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
15.3
68
235
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.9
15.0
33
69
C07AB07
ATC
bisoprolol; oral
1.8
15.0
539
4111
N02AX02
ATC
tramadol; systemic, rectal
1.7
14.9
430
3082
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
14.8
287
1833
A10BA02
ATC
metformin; oral
1.8
14.5
318
2103
H36.00
ICD-10 Finland
Diabetic background retinopathy
152.3
14.5
15
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
152.3
14.5
15
*
H54.4
ICD-10 Finland
Blindness, monocular
36.7
14.5
18
5
F29
ICPC
Eye symptom/complaint other
2.4
14.0
106
479
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.3
14.0
36
86
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
13.9
96
417
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
76.3
13.6
15
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
13.6
13
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
142.0
13.5
14
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
13.4
340
2333
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
13.4
340
2334
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.8
13.3
274
1771
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
13.2
392
2804
A10AB05
ATC
insulin aspart; parenteral
2.6
13.1
80
327
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
13.1
191
1110
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.2
12.9
117
571
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
12.9
96
431
ZXD05
NOMESCO Finland
Urgent procedure
1.7
12.8
288
1906
Z2221
NOMESCO Finland
Medical doctor
1.8
12.8
255
1630
H02AB06
ATC
prednisolone; systemic
1.7
12.7
452
3382
CKC15
NOMESCO Finland
Panretinal photocoagulation
32.5
12.6
16
5
C03CA01
ATC
furosemide; systemic
1.7
12.4
395
2865
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
12.3
260
1687
205
Kela drug reimbursment
Chronic hypertension
1.7
12.3
330
2289
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.3
12.2
93
421
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
38.1
12.2
15
*
ZXA00
NOMESCO Finland
Right side
1.7
12.1
268
1761
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.0
12.1
34
87
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
21.6
12.0
17
8
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
11.9
151
835
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
5.2
11.8
24
47
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
11.7
174
1015
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
11.5
279
1875
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
11.5
271
1809
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
11.5
11
*
C10AA07
ATC
rosuvastatin; oral
1.7
11.4
303
2086
I20.09
ICD-10 Finland
Unstable angina
2.4
11.4
83
369
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
11.2
211
1320
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
4.0
11.1
31
79
81
HP
Angiography of the heart and coronary arteries
2.2
11.0
96
460
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
11.0
96
460
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.7
11.0
61
238
A02BC02
ATC
pantoprazole; systemic
1.6
10.9
622
5147
S01EA05
ATC
brimonidine; ophthalmic
3.4
10.8
39
119
B01AA03
ATC
warfarin; systemic
1.7
10.8
253
1683
WX002
NOMESCO Finland
Sedation and analgesia
1.8
10.7
188
1152
H26.4
ICD-10 Finland
After-cataract
2.1
10.6
113
586
280
Kela drug reimbursment
Clopidogrel
3.7
10.6
33
91
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.5
10.6
70
298
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.2
10.5
41
131
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.2
10.5
94
456
H35.37
ICD-10 Finland
Macular holes
111.2
10.4
11
*
H3603, E113,
ICD-10 Finland
+∞
10.4
10
*
R4110
NOMESCO Finland
Physiotherapy
1.7
10.4
264
1790
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.1
10.3
96
473
S01ED01
ATC
timolol; ophthalmic
2.9
10.3
48
171
J01AA02
ATC
doxycycline; systemic
1.7
10.2
680
5795
M04AA01
ATC
allopurinol; systemic
1.8
10.2
172
1040
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.9
10.2
130
719
C08CA05
ATC
nifedipine; systemic
2.3
10.2
82
381
R06.0
ICD-10 Finland
Dyspnoea
1.6
10.1
281
1947
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.0
10.1
116
618
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.4
10.1
36
109
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.0
795
7092
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.9
9.9
143
822
C07AB02
ATC
metoprolol; systemic
1.7
9.9
233
1545
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
9.9
28
72
C09AA05
ATC
ramipril; oral
1.6
9.9
286
1999
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.5
9.7
61
254
ZXE00
NOMESCO Finland
One hour or less
1.6
9.5
338
2476
AN1
HP
Coronary angiography
1.8
9.5
143
834
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.2
9.5
25
61
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.7
9.4
49
185
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
9.4
372
2791
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.4
9.4
62
264
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
9.3
340
2503
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.8
9.3
19
22
ZXA05
NOMESCO Finland
Left side
1.6
9.3
237
1602
11
HP
Coronary artery bypass surgery
2.9
9.3
42
147
A10AC01
ATC
insulin (human); parenteral
2.3
9.3
73
336
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.7
9.2
50
193
M10.9
ICD-10 Finland
Gout, unspecified
2.0
9.1
96
495
C08CA10
ATC
nilvadipine; oral
3.8
9.1
27
72
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
9.1
97
503
C09CA01
ATC
losartan; oral
1.6
9.0
256
1775
A10AB04
ATC
insulin lispro; parenteral
3.8
8.8
26
69
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
8.8
143
853
I25.2
ICD-10 Finland
Old myocardial infarction
2.0
8.7
97
511
H25.8
ICD-10 Finland
Other senile cataract
1.8
8.6
127
734
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
11.7
8.6
15
13
A10BH05
ATC
linagliptin; oral
2.3
8.6
68
314
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.5
562
4671
R03AC02
ATC
salbutamol; inhalant
1.5
8.5
445
3525
RS221, ,
NOMESCO Finland
4.9
8.4
18
37
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
8.3
8
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
8.3
8
*
J01CA04
ATC
amoxicillin; systemic
1.6
8.3
669
5789
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
9.6
8.3
16
17
A10AE05
ATC
insulin detemir; parenteral
2.6
8.3
49
198
S01EE01
ATC
latanoprost; ophthalmic
2.1
8.2
77
380
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
8.2
231
1593
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
14.6
8.2
13
9
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
8.2
92
486
ZX120
NOMESCO Finland
Intravenous
2.0
8.2
98
530
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.2
8.1
31
98
H36.01
ICD-10 Finland
Diabetic maculopathy
33.7
8.1
10
*
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
33.7
8.1
10
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.9
8.1
104
576
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.0
8.1
87
453
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
8.1
79
397
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.9
219
1503
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.7
7.9
41
155
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.9
172
1112
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.6
7.9
209
1420
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.8
227
1577
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.4
7.7
19
30
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
7.7
76
383
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.0
7.7
88
468
S01EC04
ATC
brinzolamide; ophthalmic
2.5
7.6
49
206
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
2.7
7.6
41
158
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
12.0
7.6
13
11
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.3
7.5
58
265
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.3
7.5
19
45
H04AA01
ATC
glucagon; nasal, parenteral
7.2
7.5
17
24
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
4.5
7.5
18
41
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
7.4
76
388
R53
ICD-10 Finland
Malaise and fatigue
1.6
7.3
232
1640
H3600, E103,
ICD-10 Finland
+∞
7.3
7
*
H35.36
ICD-10 Finland
Macular cyst
+∞
7.3
7
*
H3601, E103,
ICD-10 Finland
+∞
7.3
7
*
WX892
NOMESCO Finland
Monitored bed care
2.0
7.3
85
455
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
4.4
7.2
18
42
A10AB01
ATC
insulin (human); parenteral
3.4
7.1
25
75
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
7.1
99
563
K78
ICPC
Atrial fibrillation/flutter
1.8
7.1
104
601
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
7.0
121
732
M10.0
ICD-10 Finland
Idiopathic gout
2.4
7.0
49
214
N03AX16
ATC
[U] pregabalin
1.6
7.0
200
1380
R4120
NOMESCO Finland
Occupational therapy
2.1
7.0
63
307
C09CA03
ATC
valsartan; oral
1.9
6.9
93
522
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
3.2
6.9
26
82
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.9
273
2023
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.5
6.8
41
167
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.8
215
1515
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
16.8
6.8
10
6
C03DA01
ATC
spironolactone; oral
1.7
6.8
142
908
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
6.7
29
99
J01DB01
ATC
cefalexin; oral
1.5
6.7
687
6084
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.4
6.7
23
68
A11CC03
ATC
alfacalcidol; systemic
2.9
6.7
30
105
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.7
125
775
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
6.7
62
306
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.9
6.6
81
441
C10AA04
ATC
fluvastatin; oral
1.8
6.6
102
598
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
8.8
6.6
13
15
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
6.5
168
1129
A10BB12
ATC
glimepiride; oral
1.9
6.5
84
465
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.7
6.5
35
135
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
3.7
6.5
20
55
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.5
360
2839
B01AC07
ATC
dipyridamole; systemic
2.0
6.5
66
337
WX872
NOMESCO Finland
Intensive care
2.1
6.5
58
282
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.5
277
2079
315
Kela drug reimbursment
Clopidogrel
3.6
6.5
21
60
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.3
6.5
24
75
I50.0
ICD-10 Finland
Congestive heart failure
1.8
6.4
103
610
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
70.3
6.4
7
*
H02.4
ICD-10 Finland
Ptosis of eyelid
2.8
6.4
31
113
S01EC54
ATC
brinzolamide, combinations; ophthalmic
3.8
6.4
19
51
D02AX
ATC
Other emollients and protectives
3.1
6.4
26
86
R51.80
ICD-10 Finland
Headache
1.7
6.4
115
705
M79.6
ICD-10 Finland
Pain in limb
1.4
6.3
351
2767
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.1
6.3
61
306
H25.0
ICD-10 Finland
Senile incipient cataract
2.0
6.3
63
320
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
6.3
92
531
R02
ICPC
Shortness of breath/dyspnoea
1.7
6.3
133
852
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
6.3
6
*
H3603, E103,
ICD-10 Finland
+∞
6.3
6
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
6.3
6
*
XF402
NOMESCO Finland
ECG with work load test
1.7
6.2
107
647
FXZ00
NOMESCO Finland
Off-pump cardiac operation
5.4
6.2
17
32
A12AA04
ATC
calcium carbonate; oral
3.4
6.2
21
62
C08CA13
ATC
lercanidipine; oral
1.6
6.2
147
970
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.0
6.1
69
365
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.1
398
3219
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
6.1
131
841
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
3.1
6.1
24
78
C10AA02
ATC
lovastatin; oral
2.2
6.0
49
229
A02BC03
ATC
lansoprazole; oral
1.5
6.0
258
1931
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
6.0
64
332
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.0
6.0
62
318
C10AB05
ATC
fenofibrate; oral
3.4
6.0
21
63
S01EA03
ATC
apraclonidine; ophthalmic
6.1
6.0
15
25
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
6.1
6.0
15
25

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
453
2638
2.41
37.21
2.9
2.2
206.27
246.36
u/l
0.27
435
2493
45
72
6.52
27.19
1.3
1.3
2.86
7.31
u/ml
0.91
28
36
584
4184
2.08
24.58
27.7
18.9
1.41
1.34
inr
1.64
492
3561
89
272
3.52
24.52
1.6
2.0
21.59
21.19
s
0.16
78
247
641
4871
2.04
21.43
7.3
5.3
7.00
6.79
mmol/l
1.58
617
4667
337
2058
2.01
21.36
5.6
4.3
84.37
84.12
%
0.06
331
2020
536
3865
1.93
20.45
7.4
5.9
0.63
0.62
e9/l
0.52
445
3293
543
3936
1.93
20.35
7.5
6.0
1.94
1.82
e9/l
0.45
464
3436
366
2341
1.94
19.97
2.9
2.3
2.97
2.98
mg/l
0.02
317
2004
535
3881
1.90
19.76
7.4
5.9
0.04
0.04
e9/l
0.18
444
3310
546
3998
1.90
19.47
7.5
6.0
0.21
0.20
e9/l
0.66
462
3468
37
68
5.63
19.44
1.1
1.2
—
—
—
0
0
435
2974
1.88
19.10
3.9
3.4
2412.02
1727.57
ng/l
1.78
387
2597
238
1331
2.06
18.90
3.5
2.7
19.42
21.82
%
2.38
223
1234
117
487
2.61
18.61
1.8
1.9
1.61
1.58
g/l
0.12
105
426
248
1415
2.03
18.60
3.4
2.7
2.22
2.24
g/l
0.20
234
1302
164
810
2.25
17.82
10.5
8.8
—
—
—
0
0
256
1515
1.96
17.10
3.4
2.7
10.44
12.04
umol/l
3.74
242
1404
498
3661
1.79
16.32
7.8
6.1
25.14
25.75
%
0.54
467
3469
386
2651
1.79
15.82
7.3
5.8
—
—
—
0
0
488
3593
1.76
15.66
7.9
6.0
59.19
58.77
%
0.31
464
3419
488
3601
1.76
15.47
7.8
6.1
0.66
0.64
%
0.31
452
3368
488
3604
1.75
15.40
7.8
6.1
9.02
9.10
%
0.25
454
3375
487
3597
1.75
15.34
7.9
6.0
3.00
2.83
%
0.79
452
3365
164
861
2.10
15.11
8.5
6.6
12.79
11.02
mmol/l
1.84
154
819
187
1032
2.02
15.05
8.1
7.8
95.50
95.19
%
0.25
180
995
202
1154
1.96
14.70
7.9
7.5
0.58
1.04
mmol/l
0.71
166
933
128
618
2.24
14.55
9.4
9.6
94.65
93.70
%
2.21
128
611
202
1161
1.95
14.41
7.9
7.5
4.94
5.11
kpa
1.83
190
1110
202
1162
1.95
14.37
7.9
7.5
11.78
11.79
kpa
0.01
191
1115
306
2009
1.78
14.29
3.3
2.5
—
—
—
0
0
201
1159
1.94
14.18
7.9
7.6
7.42
7.41
ph
0.56
98
677
560
4359
1.73
14.11
11.0
9.4
4.57
4.31
e9/l
1.52
471
3795
127
622
2.21
13.92
9.4
9.4
1.29
1.29
%
0.01
127
617
208
1228
1.90
13.61
7.9
5.6
1.05
1.02
mmol/l
1.01
197
1130
319
2147
1.74
13.52
3.5
3.0
370.68
360.78
umol/l
0.81
278
1851
266
1702
1.79
13.41
5.3
4.4
643.38
370.62
ng/l
0.61
227
1462
399
2866
1.69
13.27
4.4
3.3
6.58
7.46
mmol/l
4.81
340
2395
27
53
5.22
13.22
2.5
2.3
—
—
—
0
0
200
1183
1.88
12.95
2.5
2.5
1.86
1.81
%
0.28
174
1066
75
299
2.64
12.94
1.2
1.2
—
—
—
0
0
453
3382
1.67
12.88
4.1
3.1
139.18
149.38
ug/l
0.53
421
3078
445
3342
1.64
12.10
5.6
4.4
73.47
88.76
ng/l
0.16
359
2622
387
2806
1.65
12.09
4.5
3.3
75.54
49.16
mg/l
1.09
277
1855
395
2881
1.65
12.05
5.2
4.0
16.62
8.43
mg/mmol
2.22
270
1851
492
3796
1.64
11.95
6.2
5.2
34.22
34.65
g/l
0.86
453
3542
118
598
2.12
11.80
9.5
9.5
24.28
24.39
mmol/l
0.13
111
579
490
3817
1.61
11.13
2.5
2.3
94.78
93.52
pmol/l
0.22
293
2059
440
3342
1.61
11.10
14.5
12.5
0.00
0.00
e9/l
1.34
351
2743
768
6741
1.84
10.70
9.0
7.0
42.02
39.97
mmol/mol
7.14
721
6206
498
3919
1.59
10.65
9.5
6.8
1.20
1.21
mmol/l
0.73
469
3602
163
960
1.85
10.53
4.7
3.5
1.53
2.07
mmol/l
1.12
145
828
167
993
1.83
10.46
4.8
3.6
7.37
7.38
ph
0.61
103
595
795
7082
1.90
10.18
29.3
19.5
28.04
28.05
mg/l
0.00
711
6022
224
1463
1.70
10.12
3.1
3.2
0.82
0.82
mmol/l
0.06
214
1375
536
4325
1.57
10.03
10.3
7.5
1.21
1.21
mmol/l
0.39
473
3712
34
100
3.49
9.95
1.6
2.6
1.40
0.84
g/24h
0.70
18
58
359
2649
1.58
9.91
3.8
2.6
—
—
—
0
0
240
1616
1.66
9.59
1.6
1.7
1.17
1.46
mg/l
1.37
187
1288
743
6519
1.73
9.59
5.3
4.5
1.36
1.26
mmol/l
2.21
683
5866
231
1544
1.66
9.49
4.2
3.2
1.18
1.01
e6/l
0.22
130
873
153
915
1.81
9.35
2.4
2.5
72.80
67.52
e9/l
0.92
105
704
363
2716
1.56
9.27
5.8
4.5
—
—
—
0
0
528
4293
1.54
9.19
6.7
6.8
12.11
12.25
umol/l
0.09
506
4112
139
813
1.84
9.12
3.0
3.1
65.73
65.97
g/l
0.14
125
749
406
3137
1.53
8.83
5.9
4.2
85.28
135.28
e6/l
0.80
298
2320
137
809
1.81
8.70
3.2
2.6
5.08
7.02
ug/l
1.43
117
703
215
1441
1.64
8.65
4.4
3.3
1.54
1.97
e6/l
0.42
119
767
615
5207
1.55
8.60
6.4
5.2
631.33
2035.21
e6/l
—
6
90
459
3654
1.51
8.59
3.9
2.9
—
—
estimate
—
0
0
762
6791
1.71
8.57
6.2
5.2
1.33
1.43
mmol/l
8.55
709
6176
243
1687
1.60
8.44
1.8
1.8
1087.12
1161.60
nmol/l
0.61
184
1277
766
6844
1.71
8.44
6.4
5.3
4.05
4.40
mmol/l
18.11
719
6276
348
2623
1.53
8.38
5.6
4.4
7.40
7.40
ph
0.26
252
1926
679
5894
1.58
8.35
10.0
8.5
81.99
81.55
u/l
0.08
638
5579
150
922
1.75
8.30
1.5
1.3
531.61
454.24
titre
0.30
31
205
190
1251
1.65
8.15
2.5
2.1
—
—
—
0
0
777
6993
1.71
8.03
7.5
6.2
2.21
2.53
mmol/l
21.82
728
6372
125
741
1.79
7.81
2.9
2.4
36.66
34.43
u/l
0.28
105
622
20
48
4.24
7.76
1.2
1.2
—
—
—
0
0
116
674
1.83
7.74
2.7
2.8
—
—
—
0
0
329
2487
1.50
7.65
4.8
3.5
0.43
0.42
e6/l
0.01
251
1882
807
7363
1.78
7.65
35.8
23.8
139.35
139.58
mmol/l
1.56
789
7215
807
7370
1.77
7.53
36.3
24.1
4.01
4.01
mmol/l
0.09
787
7215
369
2866
1.48
7.46
5.1
3.7
42.09
89.06
e6/l
1.12
289
2251
493
4056
1.46
7.39
5.0
4.2
0.00
0.35
estimate
0.50
95
861
491
4047
1.46
7.22
5.0
4.2
13.08
1.77
estimate
0.40
105
916
484
3979
1.46
7.22
5.0
4.2
0.00
0.00
estimate
-0.00
105
888
762
6887
1.62
6.99
6.4
5.6
6.28
6.06
mmol/l
3.82
694
6214
400
3189
1.45
6.92
4.2
3.8
6.24
6.26
ph
0.11
197
1785
813
7484
1.74
6.79
38.0
26.0
93.69
84.34
umol/l
4.60
795
7374
79
430
1.92
6.47
2.3
2.7
16.96
23.65
au/ml
—
7
33
49
224
2.25
6.36
1.4
1.4
1.20
1.18
g/l
0.22
44
214
49
225
2.24
6.30
3.4
3.6
3.45
1.64
index
1.08
30
118
105
631
1.75
6.25
1.5
1.5
—
—
—
0
0
725
6528
1.52
6.24
5.8
5.2
2.06
2.03
mu/l
0.15
669
5921
341
2690
1.43
6.03
4.0
3.5
—
—
—
0
0
364
2908
1.42
5.98
2.4
2.3
—
—
—
0
0
815
7561
1.68
5.92
43.0
29.1
92.03
91.79
fl
0.75
800
7457
815
7562
1.68
5.91
42.9
29.1
30.45
30.46
pg
0.06
800
7458
815
7562
1.68
5.91
44.1
29.7
38.93
39.68
%
2.73
800
7450
815
7562
1.68
5.91
43.1
29.2
4.33
4.40
e12/l
2.44
787
7362
815
7562
1.68
5.91
43.5
29.4
130.31
132.79
g/l
3.99
802
7460
529
4514
1.40
5.90
3.7
3.4
57.30
55.06
u/l
0.17
495
4194
815
7563
1.68
5.89
43.1
29.2
7.51
6.93
e9/l
1.50
787
7360
298
2304
1.43
5.85
7.9
6.4
—
—
—
0
0
144
957
1.60
5.84
2.1
1.8
—
—
—
0
0
779
7156
1.58
5.80
24.6
17.7
—
—
—
0
0
814
7559
1.67
5.77
43.1
29.2
236.73
239.63
e9/l
0.62
792
7381
266
2018
1.45
5.77
3.5
3.4
0.00
0.06
—
8
66
110
685
1.69
5.77
6.1
3.9
127.82
98.81
ng/l
1.47
96
595
55
280
2.03
5.47
1.7
1.6
6.61
7.63
iu/ml
0.14
15
72
796
7386
1.58
5.25
16.8
12.8
24.43
25.28
u/l
0.85
771
7130
96
593
1.69
5.19
3.1
2.9
10.07
10.96
g/l
1.30
87
539
17
49
3.52
5.19
1.3
1.2
—
—
—
0
0
405
3355
1.37
5.14
2.7
2.4
79.15
79.22
nmol/l
0.02
359
2957
79
466
1.76
5.04
1.6
1.9
1.15
1.59
g/l
1.16
73
420
98
617
1.66
4.94
4.5
4.4
—
—
—
0
0
66
371
1.84
4.93
1.5
1.3
—
—
—
0
0
43
215
2.05
4.53
1.3
1.2
—
—
—
0
0
25
99
2.57
4.49
2.5
2.5
—
—
—
0
0
177
1298
1.45
4.49
1.9
1.6
2.60
2.65
g/l
0.12
107
758
134
933
1.51
4.40
3.0
2.7
7.66
9.19
umol/l
0.41
112
829
83
516
1.67
4.40
3.0
2.5
0.58
0.62
%
0.70
83
511
100
654
1.59
4.34
1.9
1.6
—
—
—
0
0
84
526
1.66
4.34
2.9
2.6
1.13
1.16
%
0.16
84
521
315
2560
1.35
4.34
3.0
2.6
75.49
94.46
u/l
0.25
295
2365
325
2654
1.35
4.33
2.0
1.8
20.11
19.99
nmol/l
0.05
275
2248
61
354
1.77
4.14
1.5
2.9
9.73
10.81
g/l
1.50
55
318
306
2493
1.34
4.10
2.9
3.2
31.00
34.52
u/l
1.16
283
2351
350
2909
1.33
4.09
3.5
3.5
2.35
2.35
mmol/l
0.07
313
2620
14
42
3.37
4.05
1.5
1.4
74.67
69.00
mg/l
—
9
29
633
5724
1.34
4.03
36.4
24.1
14.14
13.89
%
4.16
626
5646
34
164
2.11
3.96
1.1
1.2
65.65
55.23
u/l
0.16
28
142
8
11
7.33
3.86
1.0
1.0
—
—
—
0
0
128
913
1.47
3.74
1.7
1.5
—
—
—
0
0
619
5612
1.31
3.67
39.0
25.5
329.95
331.47
g/l
3.63
612
5571
253
2035
1.34
3.63
3.8
2.8
3.51
4.52
e6/l
1.59
233
1866
597
5392
1.31
3.60
4.3
4.1
15.05
15.07
pmol/l
0.07
545
4855
92
619
1.54
3.56
5.1
3.9
7.42
7.42
ph
0.45
78
521
15
52
2.92
3.47
1.7
1.7
38.29
39.74
%
0.12
15
52
47
267
1.80
3.46
1.7
1.6
0.24
0.31
mg/l
0.60
19
125
144
1067
1.41
3.43
1.2
1.3
—
—
—
0
0
221
1759
1.34
3.38
3.7
3.1
503.65
543.31
mosm/kgh2o
2.29
198
1544
9
18
5.04
3.37
1.1
1.3
—
—
—
0
0
54
325
1.70
3.28
3.5
3.8
2.54
2.76
ratio
0.07
30
192
26
123
2.15
3.22
1.2
1.3
—
—
—
0
0
77
512
1.55
3.16
1.2
1.2
—
—
—
0
0
54
330
1.68
3.12
3.2
3.5
1.35
1.45
mmol/l
0.39
54
323
6
8
7.54
3.06
1.2
1.1
—
—
—
0
0
39
219
1.82
3.02
1.8
1.6
14519.59
16529.73
e6/l
0.17
27
156
223
1808
1.31
2.97
3.4
3.1
2.47
2.46
mmol/l
0.22
190
1613
107
772
1.44
2.96
1.9
1.6
—
—
—
0
0
20
88
2.30
2.95
2.3
1.6
10.37
10.39
%
0.01
20
88
8
17
4.74
2.92
1.4
1.3
27.63
27.94
s
—
8
17
23
110
2.12
2.80
1.3
1.4
145.10
182.38
au/ml
—
10
25
56
356
1.61
2.80
3.7
3.8
56.76
69.52
mg/l
0.30
43
305
56
357
1.61
2.77
3.7
3.9
46.27
78.41
mg/l
0.46
44
306
30
160
1.90
2.74
1.2
1.2
—
—
—
0
0
334
2884
1.25
2.63
2.1
1.9
1.37
1.29
mmol/l
1.08
283
2390
10
30
3.36
2.60
1.1
1.1
109.00
184.69
mmol/24h
—
10
30
19
87
2.21
2.58
2.8
2.5
1408.89
1002.72
mg
0.35
19
87
25
128
1.98
2.57
1.2
1.1
—
—
—
0
0
191
1549
1.29
2.51
6.2
4.7
—
—
—
0
0
7
16
4.40
2.48
3.4
1.8
—
—
—
0
0
18
83
2.19
2.42
1.1
1.1
—
—
—
0
0
33
190
1.76
2.40
2.0
2.4
274.60
88.21
ug/min
0.44
14
115
119
909
1.36
2.38
1.8
1.7
—
—
—
0
0
64
437
1.50
2.38
5.7
4.1
—
—
—
0
0
21
104
2.04
2.37
1.3
1.1
1.53
1.53
g/l
0.03
21
90
11
39
2.84
2.35
1.5
2.2
489.55
1034.00
u/ml
1.00
11
39
63
433
1.49
2.28
1.5
1.5
—
—
—
0
0
6
13
4.64
2.27
17.5
11.9
5.03
5.45
mmol/l
—
6
13
15
67
2.26
2.18
1.1
1.1
326.00
89.00
titre
—
5
10
149
1194
1.30
2.15
1.2
1.3
50.04
36.33
iu/ml
0.54
43
365
19
95
2.02
2.11
2.8
2.5
—
—
—
0
0
17
82
2.09
2.07
1.0
1.2
—
—
—
0
0
36
223
1.64
2.05
1.6
1.6
—
—
—
0
0
94
714
1.35
1.98
5.7
4.6
0.23
0.13
%
0.26
30
200
31
187
1.68
1.96
1.4
1.2
7.00
2.65
u/ml
—
5
24
47
315
1.52
1.94
4.0
2.9
490.69
239.38
mg/l
1.50
29
125
8
27
2.98
1.94
2.0
2.3
0.63
0.60
mmol/l
—
8
27
9
33
2.74
1.93
1.2
1.0
—
—
—
0
0
96
735
1.34
1.92
1.9
2.1
407.17
387.31
nmol/l
0.21
87
677
99
764
1.33
1.88
2.6
2.2
0.00
0.02
estimate
0.50
19
140
339
3015
1.20
1.87
5.1
4.2
0.05
0.03
estimate
0.25
91
735
35
222
1.60
1.84
1.7
1.6
12.68
18.35
u/ml
—
5
45
6
17
3.55
1.84
1.2
1.1
—
—
—
0
0
128
1029
1.28
1.82
1.4
1.4
—
—
—
0
0
91
698
1.34
1.81
5.1
4.0
0.70
0.68
%
0.02
33
232
59
421
1.43
1.81
2.3
3.0
—
—
—
0
0
210
1789
1.23
1.80
5.2
4.4
1.02
1.02
kg/l
0.06
134
1214
7
23
3.06
1.80
1.0
1.1
—
13.40
—
0
5
193
2259
0.82
1.75
4.0
3.5
—
—
—
0
0
48
332
1.47
1.73
1.3
1.6
—
—
—
0
0
95
743
1.31
1.67
5.5
4.2
0.94
0.87
%
0.09
34
251
90
699
1.32
1.66
5.5
4.3
0.14
0.13
%
0.04
29
209
14
69
2.04
1.65
1.8
2.8
15.61
16.05
%
0.21
14
69
7
25
2.81
1.65
1.0
1.1
—
—
—
0
0
79
604
1.34
1.62
3.2
3.1
5.94
6.06
ph
0.64
58
433
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
7
26
2.70
1.58
1.9
3.0
—
—
—
0
0
20
115
1.76
1.53
1.2
1.1
—
—
—
0
0
5
15
3.35
1.52
3.0
5.7
—
—
—
0
0
170
1443
1.22
1.51
1.3
1.2
1.00
1.28
u/ml
0.38
32
384
17
96
1.79
1.39
1.2
1.2
116.15
50.23
mu/l
0.72
11
88
31
206
1.52
1.39
3.9
4.1
—
—
—
0
0
9
41
2.21
1.37
1.3
1.3
—
—
—
0
0
20
120
1.68
1.35
1.1
1.4
5489.10
25334.23
e6/l
—
10
69
9
42
2.15
1.34
1.9
3.3
—
—
—
0
0
11
54
2.05
1.33
1.0
1.1
0.29
3.75
u/ml
—
5
28
11
54
2.05
1.33
2.7
2.6
—
—
—
0
0
135
1136
1.22
1.32
1.2
1.3
5.10
15.75
u/ml
2.64
47
389
101
824
1.25
1.31
2.9
2.3
0.19
0.20
g/l
0.41
96
748
5
18
2.79
1.28
1.2
1.1
—
—
—
0
0
28
186
1.52
1.27
1.6
1.4
66.39
63.02
mmol/l
0.14
23
151
11
55
2.01
1.27
1.0
1.1
0.07
1.02
u/ml
—
5
21
9
44
2.06
1.27
1.7
1.6
86.44
86.50
umol/l
—
9
44
374
3439
1.15
1.26
6.1
6.0
2.40
4.35
ug/l
0.93
330
3065
16
92
1.75
1.25
1.2
1.3
—
—
—
0
0
19
115
1.67
1.25
1.3
1.2
364.15
288.39
u/ml
0.37
13
62
10
49
2.05
1.22
1.1
1.6
—
—
—
0
0
5
19
2.64
1.21
1.2
1.5
—
14.80
—
0
5
25
164
1.54
1.21
2.5
1.5
—
—
—
0
0
112
936
1.22
1.18
2.4
3.2
5.87
4.67
e9/l
0.61
96
798
81
654
1.26
1.17
4.6
3.4
—
—
—
0
0
23
150
1.55
1.15
1.5
1.3
—
—
—
0
0
27
183
1.49
1.14
5.2
5.2
2.57
2.88
mmol/l
0.24
19
123
17
103
1.66
1.13
1.1
1.0
—
—
—
0
0
48
363
1.34
1.12
1.2
1.2
81.80
133.43
u/ml
0.65
21
134
15
88
1.72
1.11
1.5
1.1
—
—
—
0
0
5
21
2.39
1.09
1.0
1.2
38.80
31.81
%
—
5
21
8
41
1.96
1.09
1.3
1.0
—
—
—
0
0
31
221
1.42
1.04
2.1
2.3
126.95
127.35
g/l
0.02
20
177
23
334
0.68
1.03
1.3
1.4
—
—
—
0
0
17
106
1.62
1.03
1.1
1.0
—
—
—
0
0
256
2322
1.14
1.03
5.8
4.2
0.00
0.00
estimate
0.75
89
800
29
205
1.43
1.02
1.0
1.1
—
—
—
0
0
21
139
1.52
1.01
1.5
1.2
42.12
59.33
u/ml
—
5
11
18
115
1.58
1.00
1.1
1.5
—
—
—
0
0
9
49
1.84
0.98
1.1
1.6
—
—
—
0
0
15
92
1.64
0.97
1.2
1.6
22.17
38.17
ng/l
0.62
15
92
9
50
1.81
0.96
2.0
1.6
98.48
98.97
ng/l
—
9
50
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
—
—
0
0
11
62
1.78
0.94
1.0
1.2
0.82
1.07
u/ml
—
5
33
10
55
1.83
0.92
1.0
1.1
0.63
0.91
u/ml
—
5
29
11
63
1.76
0.90
1.6
1.7
—
—
—
0
0
6
29
2.08
0.89
1.2
1.1
199.50
212.74
iu/ml
—
6
29
21
144
1.47
0.88
2.5
2.4
—
—
—
0
0
86
725
1.21
0.87
1.4
1.4
—
—
—
0
0
17
112
1.53
0.85
1.2
1.6
—
—
—
0
0
54
436
1.25
0.83
2.5
2.4
—
—
—
0
0
57
464
1.24
0.82
1.1
1.3
—
—
—
0
0
12
73
1.65
0.82
1.6
1.2
—
—
—
0
0
99
856
1.18
0.78
1.5
1.3
—
—
—
0
0
15
99
1.52
0.76
2.5
4.8
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
11
67
1.65
0.75
2.5
1.7
—
—
—
0
0
7
38
1.85
0.73
1.7
2.8
2262.86
1881.41
ml
—
7
32
82
702
1.18
0.73
1.6
1.5
—
—
—
0
0
5
25
2.01
0.72
2.0
2.5
—
—
—
0
0
7
39
1.80
0.72
1.9
3.3
—
—
—
0
0
88
759
1.18
0.72
2.2
2.2
183.21
153.13
ug/g
0.44
66
603
30
232
1.30
0.67
12.7
13.3
—
—
—
0
0
92
803
1.16
0.66
7.0
4.6
7.33
7.36
ph
0.74
74
581
55
459
1.21
0.66
3.3
3.9
1.02
1.02
ratio
1.13
50
423
24
181
1.33
0.63
1.1
1.2
—
—
—
0
0
19
138
1.38
0.63
1.2
1.4
754.83
1540.97
e6/l
1.77
12
100
8
49
1.64
0.62
1.1
1.1
—
—
—
0
0
13
88
1.48
0.60
1.8
1.3
12546.25
168940.96
e6/l
—
8
55
24
311
0.77
0.60
1.6
1.8
2.78
3.37
mmol/l
1.57
13
232
34
272
1.26
0.60
3.9
3.6
0.83
0.78
nmol/l
0.24
26
226
12
80
1.51
0.60
1.1
1.5
—
—
—
0
0
211
1960
1.10
0.57
1.4
1.4
—
—
—
0
0
29
230
1.27
0.56
1.5
1.4
220.58
275.87
ug/g
0.84
19
139
71
618
1.16
0.55
5.2
4.0
—
—
—
0
0
16
116
1.39
0.54
1.0
1.4
—
—
—
0
0
11
74
1.49
0.53
1.5
2.6
8.42
8.41
mmol/l
0.00
11
74
15
108
1.40
0.53
1.1
1.4
—
—
—
0
0
15
108
1.40
0.53
1.1
1.4
—
—
—
0
0
15
108
1.40
0.53
1.1
1.4
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
10
66
1.52
0.52
1.2
1.2
—
—
—
0
0
45
379
1.20
0.52
2.8
2.2
0.00
2.30
estimate
0.50
14
109
14
100
1.41
0.52
1.1
1.4
—
—
—
0
0
12
83
1.45
0.52
1.2
1.3
—
—
—
0
0
226
2122
1.09
0.49
4.8
3.7
0.04
0.05
estimate
0.05
91
681
15
110
1.37
0.49
1.1
1.4
—
—
—
0
0
7
45
1.56
0.49
4.6
3.8
180.71
150.20
nmol/l
—
7
45
11
77
1.43
0.45
1.1
1.3
—
—
—
0
0
14
104
1.35
0.43
3.0
3.8
61.11
57.37
%
0.24
14
90
43
369
1.17
0.42
1.4
1.3
—
—
—
0
0
5
33
1.52
0.41
1.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
2.03
—
0
15
8
60
1.34
0.40
2.0
2.4
—
—
—
0
0
22
178
1.24
0.39
2.1
1.7
—
—
—
0
0
9
69
1.31
0.37
1.8
1.3
—
—
—
0
0
16
128
1.25
0.32
2.4
2.9
3.96
4.65
e9/l
0.95
16
128
106
987
1.08
0.31
3.9
4.3
10.63
17.94
ug/l
0.50
93
826
7
54
1.30
0.30
1.3
1.8
—
—
—
0
0
16
129
1.24
0.30
1.2
1.2
1.53
1.51
g/l
0.09
16
129
14
111
1.27
0.30
4.4
6.4
7.01
7.21
mmol/l
—
9
93
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
20
167
1.20
0.28
2.0
1.7
2.98
38.45
iu/l
—
7
67
20
237
0.84
0.28
3.2
4.8
—
—
—
0
0
27
234
1.16
0.26
1.2
1.1
—
—
—
0
0
5
75
0.66
0.26
1.2
1.2
—
—
—
0
0
9
74
1.22
0.25
1.3
1.1
—
—
—
0
0
14
114
1.23
0.25
1.6
1.5
—
—
—
0
0
14
114
1.23
0.25
1.6
1.5
—
—
—
0
0
14
114
1.23
0.25
1.6
1.5
—
—
—
0
0
14
114
1.23
0.25
1.6
1.5
—
—
—
0
0
43
390
1.11
0.23
1.9
2.1
—
—
—
0
0
191
1838
1.05
0.22
1.8
1.8
88571845.54
14399905.28
pmol/l
0.39
140
1507
0
11
0.00
0.21
0.0
1.0
—
219.17
—
0
6
0
11
0.00
0.21
0.0
2.6
—
38.27
—
0
11
0
10
0.00
0.21
0.0
1.1
—
29.36
—
0
10
0
12
0.00
0.21
0.0
1.0
—
8.57
—
0
7
0
13
0.00
0.21
0.0
1.0
—
18.83
—
0
6
6
48
1.25
0.20
1.0
1.1
228.33
137.53
nmol/l
—
6
48
7
60
1.17
0.18
1.3
1.3
—
—
—
0
0
7
62
1.13
0.17
3.9
2.6
19.71
36.29
mg/l
—
7
49
19
167
1.14
0.17
2.4
1.9
1.00
0.84
%
0.71
14
126
16
140
1.15
0.15
1.3
1.3
0.94
0.91
g/l
0.18
16
140
9
83
1.09
0.14
1.3
1.2
—
—
—
0
0
17
150
1.14
0.14
3.0
4.2
0.97
1.76
%
0.61
17
132
8
96
0.83
0.13
3.6
2.3
—
—
—
0
0
27
292
0.92
0.12
2.7
3.2
35.96
119.84
u/ml
1.23
27
284
38
360
1.06
0.09
1.6
1.2
—
—
—
0
0
8
78
1.03
0.07
1.3
1.3
—
—
—
0
0
72
701
1.03
0.06
4.0
4.0
1.24
1.22
mmol/l
0.85
65
608
203
2004
1.02
0.06
3.5
3.5
0.88
0.82
ug/l
0.41
139
1389
23
243
0.95
0.05
1.2
1.2
—
—
—
0
0
66
675
0.98
0.04
1.9
2.3
11.84
12.64
nmol/l
0.19
53
601
17
160
1.06
0.04
2.5
2.8
55.53
60.25
%
1.08
17
160
11
101
1.09
0.04
1.0
1.3
—
—
—
0
0
18
189
0.95
0.03
1.3
1.8
42.83
41.36
nmol/l
0.09
18
178
13
134
0.97
0.00
1.8
1.6
—
—
—
0
0
14
138
1.01
0.00
2.6
2.8
—
—
—
0
0
17
168
1.01
0.00
1.0
1.1
—
—
—
0
0
25
248
1.01
0.00
2.8
3.2
1.44
1.60
mmol/l
0.62
25
240
15
151
0.99
0.00
1.5
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
84.00
—
0
8
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
5
50
1.00
-0.00
1.6
1.8
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.2
—
0.16
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_OTHRETARTOCC and mortality.

Females

Parameter HR [95% CI] p-value
H7_OTHRETARTOCC 1.324 [1.16, 1.52] < 0.001
Birth year 0.995 [0.99, 1.0] 0.249

During the follow-up period (1.1.1998 — 31.12.2019), 627 out of 1845 females with H7_OTHRETARTOCC died.

Males

Parameter HR [95% CI] p-value
H7_OTHRETARTOCC 1.387 [1.22, 1.58] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1009 out of 2645 males with H7_OTHRETARTOCC died.

Mortality risk

Mortality risk for people of age

years, who have H7_OTHRETARTOCC.

N-year risk Females Males
1 0.151% 0.239%
5 0.758% 1.507%
10 1.952% 3.968%
15 3.719% 7.186%
20 6.363% 11.684%

Relationships between endpoints

↥

Index endpoint: H7_OTHRETARTOCC – Other retinal artery occlusion

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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