LSIL lesion of the cervix uteri, vagina or vulva

N14_FEMALE_GENITAL_LSIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N87.0, N89.0, N90.0
  • Hospital discharge: ICD-9 6221A|0781C
  • Cause of death: ICD-10 N87.0, N89.0, N90.0
  • Cause of death: ICD-9 6221A|0781C

2 out of 7 registries used, show all original rules.

7045

4. Check minimum number of events

None

7045

5. Include endpoints

None

7045

6. Filter based on genotype QC (FinnGen only)

6450

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36492 36492 -
Only index persons 35540 35540 -
Unadjusted period prevalence (%)
Whole population 1.05 1.05 -
Only index persons 1.31 1.31 -
Median age at first event (years)
Whole population - 35.02 -
Only index persons - 34.91 -

-FinnGen-

Key figures

All Female Male
Number of individuals 6450 6450 -
Unadjusted period prevalence (%) 2.29 2.29 -
Median age at first event (years) 36.99 36.99 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6693
Matched controls
66930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
40.4
323.0
196
50
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
24.7
307.7
257
108
N90.0
ICD-10 Finland
Mild vulvar dysplasia
5012.5
307.7
477
*
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.4
307.7
1809
2110
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
5.7
307.7
727
1398
N87.1
ICD-10 Finland
Moderate cervical dysplasia
8.8
307.7
876
1127
N87.0
ICD-10 Finland
Mild cervical dysplasia
4637.3
307.7
5171
49
ULA02
NOMESCO Finland
Kolposcopy
26.3
307.7
4831
6010
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
16.6
307.7
2422
2216
LEB00
NOMESCO Finland
Biopsy of vagina
12.9
307.7
686
588
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
22.5
307.7
4671
6235
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
307.7
650
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
6.5
307.7
614
1018
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
8.7
307.7
705
898
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
10.7
307.7
900
954
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
18.0
307.7
3543
3928
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.4
307.7
3726
7867
N89.0
ICD-10 Finland
Mild vaginal dysplasia
6542.4
307.7
607
*
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
75.7
307.7
184
25
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.3
307.7
1100
1753
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
13.4
307.7
371
292
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
40.5
216.1
131
33
8411
FHL
Local change laser, coagulation, biopsy or removal
45.5
212.1
125
28
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
+∞
198.9
190
*
ZXC00
NOMESCO Finland
Use of diathermy
12.2
190.9
192
162
8326
FHL
Batch conization
17.7
185.5
151
87
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
32.2
137.9
89
28
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
15.0
136.7
121
82
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
22.3
134.9
99
45
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
24.4
132.7
94
39
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
15.9
122.4
105
67
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
120.1
3359
23899
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
25.9
118.3
82
32
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
9.7
117.0
137
144
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
7.8
113.7
159
209
G01AA10
ATC
clindamycin; vaginal
1.9
109.0
1756
10451
D06BB10
ATC
imiquimod; topical
2.9
98.1
478
1704
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
8.4
94.1
123
149
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
19.1
89.3
70
37
D06BB04
ATC
podophyllotoxin; topical
2.4
88.7
650
2839
X86
ICPC
Abnormal cervix smear
4.4
83.8
212
490
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
4.8
69.2
159
340
LDB10
NOMESCO Finland
Cryotherapy of cervix uteri
9.3
67.5
81
88
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
8.8
59.0
74
85
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
52.1
1204
7746
C539, 6666, 0
ICD-O-3
3.8
49.9
151
399
J02AC01
ATC
fluconazole; systemic
1.5
48.6
3588
29570
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.6
48.6
1273
8439
1390
FHL
Colposcopy
12.9
47.7
46
36
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
15.1
47.6
42
28
P01AB01
ATC
metronidazole; oral, rectal
1.5
47.4
3039
24340
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
46.8
2246
16993
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
12.5
41.8
41
33
N93.0
ICD-10 Finland
Postcoital and contact bleeding
3.5
40.4
143
420
X23
ICPC
Fear sexually transm dis female
1.8
40.4
656
3806
Z3231
NOMESCO Finland
Registered nurse
1.5
40.0
1548
11143
Z2221
NOMESCO Finland
Medical doctor
1.4
37.6
1888
14274
Z3232
NOMESCO Finland
Midwife
1.6
37.0
1020
6799
N76.0
ICD-10 Finland
Acute vaginitis
1.6
33.6
816
5268
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
6.2
32.5
55
89
G01AF01
ATC
metronidazole; vaginal
1.6
32.2
778
5012
N72
ICD-10 Finland
Inflammatory disease of cervix uteri
3.8
31.2
96
257
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
29.7
1801
13972
N87
ICD-10 Finland
Dysplasia of cervix uteri
8.3
29.1
38
46
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
28.9
2146
17187
LFC00
NOMESCO Finland
Partial excision of vulva
6.7
28.4
45
68
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.7
27.8
520
3132
LDC00
NOMESCO Finland
Conisation of cervix uteri using knife
10.4
27.1
30
29
TLC02
NOMESCO Finland
Simple extraction of IUD
1.7
26.3
494
2978
N07BA03
ATC
varenicline; oral
1.9
25.3
339
1848
R2110
NOMESCO Finland
Giving the first information
1.6
25.1
559
3521
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
24.0
369
2099
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.4
23.1
1069
7866
R87.2
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of other drugs, medicaments and biological substances
6.5
23.0
37
57
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.5
22.5
914
6562
R87.8
ICD-10 Finland
Abnormal findings in specimens from female genital organs, other abnormal findings
4.1
22.2
60
147
SPAT1193
SPAT
Pap smear
1.4
22.1
1040
7667
M03BX02
ATC
tizanidine; oral
1.3
21.6
4263
38509
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
21.5
2118
17495
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
21.4
4811
44192
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
20.9
2625
22362
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
2.1
20.6
196
948
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
20.6
5049
46770
N02AX02
ATC
tramadol; systemic, rectal
1.3
20.6
2264
18951
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
20.5
2554
21717
ZXC10
NOMESCO Finland
Use of laser
2.5
20.3
127
514
J05AB01
ATC
aciclovir; systemic
1.3
20.1
1463
11563
J01CA08
ATC
pivmecillinam; oral
1.3
19.7
3501
31037
X92
ICPC
Chlamydia infection genital female
2.3
19.2
142
620
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
1.9
19.2
248
1336
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
19.2
3245
28562
X15
ICPC
Vaginal symptom/complaint other
1.6
19.1
424
2667
SDA03
NOMESCO Finland
Periodontal treatment
1.3
19.1
2864
24849
M54.5
ICD-10 Finland
Low back pain
1.3
19.0
2497
21314
8113
FHL
Fractional scraping
1.8
19.0
263
1449
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
2.1
18.6
170
811
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
18.6
347
2087
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.5
18.4
543
3647
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
18.3
2004
16709
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
2.2
17.9
153
711
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
17.9
959
7212
Z01.2
ICD-10 Finland
Dental examination
1.3
17.8
3291
29164
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
17.7
3898
35228
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
17.5
2001
16752
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
15.6
17.4
28
18
Z71.8
ICD-10 Finland
Other specified counselling
1.3
17.4
2377
20323
L04AX01
ATC
azathioprine; systemic
1.8
17.3
259
1463
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.4
16.9
706
5081
J01AA02
ATC
doxycycline; systemic
1.3
16.8
4889
45491
SPAT1308
SPAT
Sexual health counselling
1.3
16.7
1234
9736
SFA10
NOMESCO Finland
One-surface restoration
1.2
16.4
3695
33332
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
16.2
911
6896
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
16.0
2363
20332
R87.1
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of hormones
6.2
15.9
27
44
J01DB01
ATC
cefalexin; oral
1.3
15.7
5397
50976
8339
FHL
Other measure in this category
5.6
15.5
29
52
A02BC02
ATC
pantoprazole; systemic
1.2
15.0
4054
37111
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
14.9
2570
22442
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
14.9
4782
44588
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
3.5
14.8
50
144
SFA20
NOMESCO Finland
Two-surface restoration
1.2
14.7
3998
36589
8077/2-C53.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of exocervix
5.6
14.6
27
48
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.4
14.5
703
5188
N90.4
ICD-10 Finland
Leukoplakia of vulva
4.0
14.5
40
100
N30.0
ICD-10 Finland
Acute cystitis
1.3
14.3
1235
9933
J01EA01
ATC
trimethoprim; systemic
1.3
14.3
1771
14893
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
14.1
1402
11482
N02BE01
ATC
paracetamol; systemic, rectal
1.3
13.6
5768
55210
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.6
13.2
322
2072
XLA10, ,
NOMESCO Finland
1.5
13.1
374
2493
J05AB11
ATC
valaciclovir; oral
1.3
13.1
908
7082
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
5.5
13.0
25
46
J01DA01
ATC
[U] cefalexin
1.2
13.0
3874
35548
N03AX16
ATC
[U] pregabalin
1.3
12.9
1177
9520
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
12.9
2578
22749
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
2.2
12.9
106
486
UJF32
NOMESCO Finland
Coloscopy
1.3
12.9
1158
9349
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.3
12.7
1482
12347
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.4
12.7
694
5220
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
12.7
1342
11057
LCH11
NOMESCO Finland
Pharmacologic abortion
1.5
12.6
414
2841
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
12.6
3054
27439
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.5
12.5
471
3320
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
12.5
2562
22645
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
3.6
12.5
41
116
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
20.0
12.4
18
9
D19
ICPC
Teeth/gum symptom/complaint
1.2
12.3
2126
18467
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
12.3
610
4518
N76.6
ICD-10 Finland
Ulceration of vulva
2.4
12.2
85
364
L04AD02
ATC
tacrolimus; systemic
3.0
12.2
53
179
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
12.1
3579
32710
N06AB04
ATC
citalopram; systemic
1.3
12.1
1240
10173
N06AX11
ATC
mirtazapine; oral
1.2
12.1
2068
17944
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
12.0
581
4284
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.6
11.9
253
1576
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
11.8
4486
41931
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2.6
11.7
65
250
K02.1
ICD-10 Finland
Caries of dentine
1.2
11.7
3999
36982
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
11.7
4078
37782
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
2.5
11.7
69
274
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
11.6
2085
18166
ULC02
NOMESCO Finland
Hysteroscopy
1.5
11.5
386
2661
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
1.5
11.5
353
2392
L04AA01
ATC
[U] ciclosporin
2.4
11.4
74
307
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
4.5
11.4
27
60
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
4.1
11.3
30
73
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
1.8
11.2
166
937
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
11.2
2573
22915
WZA90
NOMESCO Finland
Other medical or dental certificate
1.2
11.2
1357
11336
EBA00
NOMESCO Finland
Extraction of tooth
1.2
11.2
2075
18113
127
Kela drug reimbursment
Transplant complication
2.5
11.2
68
274
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
11.1
1908
16528
R4110
NOMESCO Finland
Physiotherapy
1.2
11.1
1378
11539
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
1.6
11.0
224
1380
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.3
10.8
930
7455
C07AA05
ATC
propranolol; systemic
1.2
10.8
1358
11384
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.4
10.8
590
4436
M01AH05
ATC
etoricoxib; oral
1.2
10.8
3980
36922
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.3
10.7
636
4843
X14
ICPC
Vaginal discharge
1.6
10.6
237
1496
ZXE00
NOMESCO Finland
One hour or less
1.2
10.5
2297
20331
L29.2
ICD-10 Finland
Pruritus vulvae
1.8
10.5
156
882
K05.31
ICD-10 Finland
Periodontitis pronounced
1.4
10.4
446
3219
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
10.4
1263
10542
7020X
ICD-9 Finland
Other dermatoses, Actinic keratosis[DERMATOSES PRAECANCEROSAE ALIAE]
110.2
10.4
11
*
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
1.5
10.4
299
1999
D07AD01
ATC
clobetasol; topical
1.3
10.4
933
7520
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.2
10.3
1773
15338
A05
ICPC
Feeling ill
1.5
10.3
367
2561
N30
ICD-10 Finland
Cystitis
1.3
10.3
663
5111
N05CF01
ATC
zopiclone; oral
1.2
10.3
1567
13401
R74
ICPC
Upper respiratory infection acute
1.2
10.2
2683
24119
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.2
10.2
1206
10041
M79.6
ICD-10 Finland
Pain in limb
1.2
10.0
2814
25431
N95.0
ICD-10 Finland
Postmenopausal bleeding
1.4
10.0
497
3680
L13
ICPC
Hip symptom/complaint
1.3
10.0
961
7807
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
10.0
767
6059
WZC00
NOMESCO Finland
Treatment plan or consultation
1.2
9.9
2168
19165
Z00.0
ICD-10 Finland
General medical examination
1.3
9.9
976
7951
G01AF04
ATC
miconazole; vaginal
1.5
9.9
357
2500
WX290
NOMESCO Finland
Other blockage of nerve
1.2
9.8
3347
30730
Z3226
NOMESCO Finland
Physiotherapist
1.3
9.7
863
6944
H02AB06
ATC
prednisolone; systemic
1.2
9.7
2661
23987
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
7.8
9.6
21
27
8112
FHL
Scraping the cervix
7.8
9.6
21
27
D06.1
ICD-10 Finland
Carcinoma in situ: Exocervix
3.7
9.6
29
78
N05BA04
ATC
oxazepam; oral
1.2
9.6
1570
13509
XLD00, ,
SPAT
1.8
9.6
143
812
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.3
9.5
560
4257
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.3
9.5
578
4416
J01MA02
ATC
ciprofloxacin; systemic
1.2
9.5
1841
16089
P01
ICPC
Feeling anxious/nervous/tense
1.2
9.5
1106
9185
M01AB05
ATC
diclofenac; systemic, rectal
1.2
9.5
4029
37614
R53
ICD-10 Finland
Malaise and fatigue
1.2
9.4
1586
13675
R05
ICPC
Cough
1.2
9.4
1550
13339
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.2
9.4
1337
11342
N88.9
ICD-10 Finland
Noninflammatory disorder of cervix uteri, unspecified
5.1
9.3
19
37
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
4.4
9.3
23
53
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.2
9.2
1084
9005
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
1.7
9.1
179
1096
N63
ICD-10 Finland
Unspecified lump in breast
1.3
9.1
559
4280
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
4.8
9.0
20
42
R51.80
ICD-10 Finland
Headache
1.2
9.0
1121
9367
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
3.4
9.0
31
91
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
10.0
9.0
17
17
M25.5
ICD-10 Finland
Pain in joint
1.2
9.0
2202
19622
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.2
9.0
1180
9923
WX002
NOMESCO Finland
Sedation and analgesia
1.3
8.9
813
6556
D82
ICPC
Teeth/gum disease
1.2
8.9
2544
22950
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
8.9
1125
9416
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.2
8.9
1592
13798
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
8.8
2367
21249
ZX120
NOMESCO Finland
Intravenous
1.4
8.8
417
3067
J01FF01
ATC
clindamycin; systemic
1.2
8.8
1434
12321
LEB10
NOMESCO Finland
Excision of lesion of vagina
2.8
8.7
42
151
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
2.0
8.7
89
447
M01AE01
ATC
ibuprofen; systemic, rectal
1.3
8.7
6102
59404
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
8.6
890
7283
SFA00
NOMESCO Finland
Small restoration
1.3
8.6
818
6633
A02BC03
ATC
lansoprazole; oral
1.2
8.5
1357
11624
6230A
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE LEVIS]
20.0
8.5
12
6
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
8.4
1663
14532
E000006, ,
ATC
1.4
8.3
347
2495
W11
ICPC
Contraception oral
1.3
8.3
814
6622
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.2
8.3
1298
11097
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
8.3
2294
20612
SFA30
NOMESCO Finland
Three-surface restoration
1.2
8.3
2444
22077
R07.4
ICD-10 Finland
Chest pain, unspecified
1.2
8.2
1227
10444
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
3.5
8.1
27
78
A11CC03
ATC
alfacalcidol; systemic
2.0
8.1
79
391
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
10.0
8.0
15
15
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.5
8.0
240
1624
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
8.0
837
6864
H02AB07
ATC
prednisone; oral
1.3
8.0
641
5091
J01FA10
ATC
azithromycin; systemic
1.2
7.9
3941
36976
8511
FHL
Cervical dilation and drainage with suction
1.5
7.9
226
1513
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
3.0
7.9
33
110
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.5
7.8
244
1663
ZXA00
NOMESCO Finland
Right side
1.2
7.8
1039
8737
Z2446
NOMESCO Finland
Social worker
1.4
7.8
312
2229
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.6
7.8
186
1198
A06AC01
ATC
ispaghula (psylla seeds); oral
1.2
7.7
1340
11563
K30
ICD-10 Finland
Functional dyspepsia
1.3
7.7
703
5670
P17
ICPC
Tobacco abuse
2.0
7.7
83
426
R87
ICD-10 Finland
Abnormal findings in specimens from female genital organs
3.5
7.7
25
71
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.2
7.7
857
7074
Z29.8
ICD-10 Finland
Other specified prophylactic measures
1.6
7.7
178
1138
U02
ICPC
Urinary frequency/urgency
1.2
7.7
887
7351
S18
ICPC
Laceration/cut
1.2
7.7
2304
20807
W12
ICPC
Contraception intrauterine
1.2
7.6
1030
8673
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
1.9
7.6
88
462
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.3
7.6
442
3356
P01BA02
ATC
hydroxychloroquine; oral
1.3
7.6
458
3499
E0000UV, ,
ATC
1.2
7.5
2574
23460
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.3
7.5
550
4313
K05.30
ICD-10 Finland
Periodontitis complex
1.3
7.5
687
5541
J01CA04
ATC
amoxicillin; systemic
1.2
7.5
5439
52439
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
7.5
564
4442
K02.0
ICD-10 Finland
Caries limited to enamel
1.2
7.5
1436
12500
G44.2
ICD-10 Finland
Tension-type headache
1.2
7.4
967
8113
KMAK, ,
NOMESCO Finland
1.2
7.4
3485
32486
G01AF05
ATC
econazole; vaginal
1.3
7.4
594
4715
A56.2
ICD-10 Finland
Chlamydial infection of genitourinary tract, unspecified
2.8
7.4
35
125
M03BC01
ATC
orphenadrine (citrate); systemic
1.2
7.4
1437
12521
L04AA06
ATC
mycophenolic acid; systemic
1.9
7.3
85
447
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
1.5
7.3
250
1735
N06AX16
ATC
venlafaxine; oral
1.2
7.3
973
8183
Z30.2
ICD-10 Finland
Sterilization
1.2
7.3
775
6363
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.2
7.2
1516
13288
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.2
7.2
1096
9332
L03
ICPC
Low back symptom/complaint
1.2
7.2
1845
16435
F32.1
ICD-10 Finland
Moderate depressive episode
1.3
7.2
473
3657
K50.8
ICD-10 Finland
Other Crohn disease
1.9
7.2
87
465
N06AB10
ATC
escitalopram; oral
1.2
7.2
1478
12939
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.2
7.1
733
5997
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
7.1
42
169
XF400
NOMESCO Finland
ECG with 12 standard connections
1.3
7.0
495
3863
SPAT1283
SPAT
Restricted health certificate
1.2
7.0
1449
12681
A12AA04
ATC
calcium carbonate; oral
2.4
7.0
47
200
A03
ICPC
Fever
1.2
7.0
1171
10061
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
1.5
7.0
234
1620
TK810
NOMESCO Finland
Hemofiltration
3.9
7.0
20
52
SPAT1192
SPAT
Gynaecological examination
1.2
7.0
911
7645
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
2.9
6.9
30
102
ZXE20
NOMESCO Finland
More than three and less than five hours
1.3
6.9
485
3787
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.8
1960
17600
K07.60
ICD-10 Finland
Snapping jaw
1.3
6.8
403
3069
WX408
NOMESCO Finland
General anesthesy, balanced
1.2
6.8
1248
10807
N06AX21
ATC
duloxetine; oral
1.2
6.8
744
6125
Z72.0
ICD-10 Finland
Tobacco use
1.6
6.8
132
810
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.4
6.8
309
2261
A07EC02
ATC
mesalazine; oral, rectal
1.4
6.8
264
1881
N89.3
ICD-10 Finland
Dysplasia of vagina, unspecified
16.7
6.7
10
6
R42
ICD-10 Finland
Dizziness and giddiness
1.2
6.7
1110
9522
M01AE02
ATC
naproxen; oral, rectal
1.1
6.7
3630
34064
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.3
6.7
646
5244
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.2
6.7
873
7323
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
1.7
6.7
109
638
09992
ICD-8 Finland
Other veneral disease, Condyloma acuminatum
3.3
6.7
24
73
D06BB03
ATC
aciclovir; topical
1.4
6.7
263
1877
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
1.4
6.6
262
1870
N03AX12
ATC
[U] gabapentin; oral
1.2
6.6
776
6439
L04AX03
ATC
methotrexate; systemic
1.3
6.6
511
4043
N05AH04
ATC
quetiapine; oral
1.2
6.5
1055
9032
N86
ICD-10 Finland
Erosion and ectropion of cervix uteri
2.6
6.5
35
134
Z94.4
ICD-10 Finland
Liver transplant status
3.8
6.5
19
50
G04BD12
ATC
mirabegron; oral
1.3
6.5
401
3073
G03CA04
ATC
estriol; systemic, vaginal
1.5
6.5
195
1321
J02AC02
ATC
itraconazole; systemic
1.2
6.5
1010
8615
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
1.7
6.5
102
591
D11
ICPC
Diarrhoea
1.2
6.5
814
6800
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.2
6.5
1112
9571
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.2
6.5
828
6932
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.3
6.4
465
3643
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.2
6.4
857
7204
M01AH01
ATC
celecoxib; oral
1.2
6.4
812
6791
A02BC05
ATC
esomeprazole; systemic
1.1
6.4
2237
20363
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
1.7
6.4
114
685
X59
ICD-10 Finland
Exposure to unspecified factor
1.2
6.4
920
7795
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.2
6.3
1502
13281
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
1.9
6.3
76
406
R87.4
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal immunological findings
8.1
6.3
13
16
A04
ICPC
Weakness/tiredness general
1.2
6.3
879
7420
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.3
6.3
372
2834
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.3
6.3
426
3308
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.4
6.3
313
2324
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.4
6.3
246
1755
G01AX03
ATC
policresulen; vaginal
2.1
6.3
57
276
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.1
6.2
56
270
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
26.7
6.2
8
*
-1, ,
NOMESCO Finland
1.2
6.2
2033
18407
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.2
6.2
739
6139
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.3
6.2
444
3474
4044, ,
NOMESCO Finland
7.0
6.2
14
20
TK800
NOMESCO Finland
Hemodialysis
2.1
6.2
58
284
G03AC03
ATC
levonorgestrel; oral, implant
1.2
6.2
817
6859
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
1.5
6.2
174
1164
R03AC02
ATC
salbutamol; inhalant
1.1
6.2
3561
33470
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
1.2
6.2
1208
10514
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.1
6.2
56
271
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.2
6.1
1800
16167
ZXA05
NOMESCO Finland
Left side
1.2
6.1
934
7954
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.2
6.1
1610
14350
L01BB02
ATC
mercaptopurine; oral
1.9
6.1
69
362
J01FA06
ATC
roxithromycin; oral
1.1
6.1
2277
20808
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
2.0
6.0
63
321
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.4
6.0
210
1467
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
6.0
1306
11463

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1407
1894
9.14
307.65
2.7
1.7
—
—
—
0
0
3902
26641
2.11
187.59
2.7
2.0
—
—
—
0
0
727
4629
1.64
31.54
1.4
1.4
—
—
—
0
0
1121
8142
1.45
26.28
2.9
2.7
4.74
4.73
e6/l
0.01
543
3683
2084
16982
1.33
23.92
3.4
3.0
29.69
64.75
e6/l
2.58
1553
12614
4917
45110
1.34
23.37
4.7
4.2
10.04
10.14
mm/h
0.24
4701
42989
1270
9710
1.38
21.80
1.7
1.6
—
—
—
0
0
1180
8938
1.39
21.39
2.8
2.6
1.05
1.19
e6/l
0.44
600
4494
2506
21192
1.29
21.25
4.3
3.6
59.05
77.87
e6/l
1.71
1702
13933
4445
40574
1.28
19.67
4.7
4.3
1223.88
2176.83
e6/l
0.78
41
455
1812
14798
1.31
19.64
3.9
3.6
1.00
0.23
1.13
11
116
1792
14672
1.30
18.92
3.3
2.9
0.36
0.32
e6/l
0.28
1265
10414
2280
19265
1.28
18.81
2.4
2.1
—
—
—
0
0
3524
31385
1.26
18.59
7.2
6.2
0.52
0.53
e9/l
0.55
3143
27681
3700
33166
1.26
18.35
3.9
3.6
0.00
0.00
estimate
0.17
746
7002
4720
43580
1.28
18.13
8.5
7.5
72.56
73.96
u/l
1.90
4485
41607
3523
31443
1.25
17.96
7.3
6.3
0.04
0.04
e9/l
0.69
3138
27689
3724
33462
1.25
17.84
3.9
3.6
3.69
4.38
estimate
0.10
759
7081
771
5610
1.42
17.39
2.1
2.0
0.01
0.04
estimate
3.23
180
1281
3862
34907
1.25
17.30
10.0
9.2
3.91
3.95
e9/l
0.64
3401
30722
3739
33700
1.25
17.06
4.0
3.7
0.00
0.16
estimate
0.57
728
6902
3616
32552
1.24
16.34
7.4
6.4
0.18
0.18
e9/l
1.29
3301
29148
3580
32255
1.24
15.81
7.3
6.2
1.99
1.96
e9/l
0.77
3306
29082
4543
42095
1.25
15.09
4.9
4.3
3.67
2.27
—
6
43
2608
22918
1.23
13.97
6.2
5.4
1.22
1.22
mmol/l
0.21
2443
21413
3038
27120
1.22
13.91
10.4
9.8
0.00
0.00
e9/l
1.07
2477
22213
562
4020
1.43
13.84
1.3
1.2
—
—
—
0
0
3192
28683
1.22
13.53
7.3
6.3
2.73
2.77
%
0.50
3014
27077
3251
29279
1.21
13.43
7.2
6.1
56.02
56.48
%
1.71
3111
28131
3187
28650
1.21
13.40
7.3
6.4
0.69
0.70
%
0.23
3007
26976
3192
28721
1.21
13.23
7.4
6.4
8.26
8.21
%
0.49
3018
27160
742
5607
1.36
13.21
2.5
2.4
40.78
35.98
u/l
0.38
622
4724
3221
29118
1.20
12.37
6.2
5.8
9.45
9.69
umol/l
0.92
3080
27646
1664
14094
1.24
12.28
4.3
3.5
96.27
97.65
%
1.69
1620
13707
2060
17872
1.22
12.03
6.5
5.9
—
—
—
0
0
1273
10509
1.26
11.72
2.7
2.5
112.55
102.07
ug/g
0.53
1027
8325
2968
26718
1.20
11.67
3.5
3.2
6.22
6.23
ph
0.27
1643
15455
3272
29738
1.20
11.52
7.3
6.2
29.99
29.56
%
1.80
3127
28388
2656
23702
1.20
11.39
5.2
4.5
36.94
36.85
g/l
0.39
2537
22405
2886
25976
1.20
11.20
6.9
6.0
1.22
1.22
mmol/l
0.40
2571
22597
2623
23468
1.19
10.73
2.0
1.9
98.47
99.47
pmol/l
0.54
1431
12453
1025
8351
1.27
10.44
1.2
1.2
—
—
—
0
0
1378
11631
1.23
10.24
2.8
2.5
7.92
8.50
e6/l
0.56
1249
10495
1788
15504
1.21
10.14
1.5
1.5
2.16
2.14
g/l
0.35
1132
10186
274
1811
1.53
10.06
1.2
1.1
—
—
—
0
0
6011
58285
1.31
9.74
14.2
12.6
3.90
3.90
mmol/l
0.13
5914
57021
6000
58176
1.30
9.63
14.0
12.4
139.60
139.62
mmol/l
0.32
5915
57046
6152
59894
1.34
9.29
14.4
12.4
19.22
19.17
mg/l
0.04
5034
48328
660
5158
1.31
9.26
2.2
2.4
6.11
6.16
ph
0.77
408
3189
2073
18346
1.19
9.23
1.4
1.3
1.40
1.47
u/ml
0.10
652
5469
2174
19328
1.18
9.16
3.0
2.7
0.19
0.04
0.79
31
296
847
6857
1.27
9.03
1.8
1.7
—
—
—
0
0
1990
17592
1.19
8.90
4.0
3.8
0.00
0.00
estimate
0.06
729
6759
1534
13248
1.20
8.89
1.8
1.8
—
—
—
0
0
1799
15765
1.19
8.89
4.7
3.7
7.40
7.40
ph
0.64
1275
11083
1218
10335
1.22
8.42
2.5
2.5
2.42
2.43
mmol/l
0.30
1062
9284
802
6503
1.27
8.42
1.5
1.5
—
—
—
0
0
2039
18140
1.18
8.35
2.6
2.5
55.20
58.50
u/l
1.86
1920
16933
1155
9779
1.22
8.14
3.1
2.6
487.21
509.71
mosm/kgh2o
2.96
1029
8523
383
2814
1.38
8.12
2.2
2.0
0.02
0.03
estimate
0.11
161
1042
442
3330
1.35
8.01
2.8
2.1
12.28
7.16
iu/ml
1.63
131
814
820
6707
1.25
7.98
1.4
1.4
—
—
—
0
0
565
4418
1.30
7.90
1.8
1.9
—
—
—
0
0
2188
19652
1.17
7.85
3.3
3.3
2.35
2.35
mmol/l
1.03
2007
18256
6357
62369
1.38
7.65
16.5
14.5
67.19
66.67
umol/l
1.09
6298
61766
1674
14768
1.18
7.43
2.2
2.0
—
—
—
0
0
1254
10829
1.19
7.10
1.5
1.4
516.12
566.75
titre
0.56
299
2347
3195
29665
1.15
7.04
2.7
2.5
76.87
3012.11
nmol/l
0.50
2989
27925
5733
55623
1.21
6.99
4.4
4.2
5.60
5.63
mmol/l
0.97
5432
52660
1632
14433
1.17
6.96
1.7
1.6
21.13
20.78
nmol/l
0.46
1460
12696
1866
16685
1.16
6.91
1.8
1.8
—
—
—
0
0
210
1429
1.48
6.83
3.8
2.6
1.40
2.15
index
1.23
119
715
1694
15047
1.17
6.81
1.4
1.4
26.01
26.22
iu/ml
0.02
521
4525
5530
53504
1.19
6.78
5.1
5.0
36.95
37.35
mmol/mol
3.58
5295
51188
2781
25644
1.14
6.64
3.6
3.4
1.05
0.15
estimate
0.53
598
5804
6356
62460
1.35
6.62
12.0
10.6
23.60
23.91
u/l
0.52
6252
61202
2331
21242
1.15
6.59
3.7
3.1
30.26
29.53
u/l
0.15
2222
20258
1646
14633
1.17
6.50
4.0
3.6
1.02
1.23
kg/l
0.81
1049
9498
728
6014
1.24
6.45
7.1
4.9
1.04
1.04
mmol/l
0.23
673
5575
39
159
2.46
6.41
3.5
2.5
0.60
0.62
mmol/l
1.04
39
159
1560
13851
1.16
6.23
1.4
1.3
8.27
8.81
u/ml
0.16
676
5967
448
3512
1.30
6.18
8.6
8.4
—
—
—
0
0
2187
19916
1.15
6.14
2.3
2.1
—
—
—
0
0
5969
58275
1.22
6.08
6.2
6.0
1.71
1.75
mu/l
1.24
5724
55836
1696
15188
1.16
6.01
2.0
2.1
126.31
139.60
u/l
0.78
1634
14505
5418
52481
1.17
5.83
5.2
5.0
14.38
14.35
pmol/l
0.42
5161
49882
970
8330
1.19
5.77
1.2
1.2
—
—
—
0
0
57
286
2.00
5.73
3.3
2.9
42.16
47.04
%
1.27
26
183
1637
14672
1.15
5.69
1.7
1.7
0.93
0.90
mg/l
0.20
1223
11197
427
3372
1.28
5.59
9.2
6.8
7.97
7.52
mmol/l
0.79
411
3246
2662
24687
1.13
5.48
1.8
1.8
1.32
1.32
mmol/l
0.06
2350
21607
845
7200
1.20
5.48
1.6
1.4
—
—
—
0
0
5666
55160
1.18
5.37
3.8
3.7
1.19
1.20
mmol/l
0.47
5402
52506
287
2165
1.34
5.26
1.4
1.4
27.25
25.73
u/l
0.34
234
1779
218
2969
0.73
5.14
1.5
1.5
59.97
59.66
ug/l
0.04
218
2969
193
1373
1.42
5.08
1.6
1.6
389.92
386.24
mu/l
0.03
153
1105
591
4901
1.23
5.07
3.2
2.8
10.41
10.45
g/l
0.09
557
4540
4635
44554
1.13
5.03
3.3
3.0
34.53
34.98
u/l
0.20
4475
42738
6600
65444
1.61
5.02
21.6
19.3
90.93
90.44
fl
17.63
6567
65079
6600
65444
1.61
5.02
21.6
19.3
30.26
30.07
pg
17.77
6567
65080
960
8334
1.18
5.01
3.5
3.1
0.82
0.82
mmol/l
0.67
906
7885
6601
65458
1.61
5.00
21.8
19.4
6.67
6.65
e9/l
0.21
6504
64468
798
6821
1.19
4.99
3.0
2.4
5.52
6.29
umol/l
1.03
687
5805
6600
65450
1.60
4.94
22.0
19.6
40.54
40.38
%
0.10
6566
65054
66
367
1.81
4.93
2.9
3.0
0.66
0.84
e9/l
2.69
66
356
6600
65451
1.60
4.93
21.7
19.4
4.42
4.45
e12/l
5.76
6501
64493
305
2346
1.31
4.90
3.0
2.0
0.22
0.23
g/l
1.12
289
2242
621
5196
1.22
4.88
2.4
2.4
20.26
20.99
au/ml
0.09
78
714
468
3811
1.25
4.77
1.1
1.1
35.80
2.51
u/ml
—
9
37
15
42
3.58
4.76
7.3
12.5
5.05
4.86
mmol/l
0.08
15
42
487
3987
1.24
4.73
2.6
2.2
0.38
0.34
e6/l
0.11
453
3735
6600
65467
1.59
4.72
21.8
19.5
133.07
133.01
g/l
0.16
6569
65101
411
3307
1.26
4.66
1.4
1.3
1.87
1.16
u/ml
0.33
34
250
639
5387
1.21
4.65
2.7
3.0
30.02
43.51
u/ml
2.46
613
5230
191
1382
1.39
4.60
1.5
1.5
11.67
13.36
iu/ml
—
7
31
5977
58577
1.19
4.60
4.5
4.3
4.82
4.84
mmol/l
1.10
5772
56234
1001
8779
1.16
4.59
3.2
3.1
166.08
292.60
ng/l
1.50
554
4950
578
4836
1.21
4.56
1.3
1.3
33.36
44.33
au/ml
0.73
24
289
77
459
1.69
4.55
1.1
1.2
26.00
98.75
titre
—
5
8
77
459
1.69
4.55
1.1
1.2
424.00
190.90
titre
0.91
15
89
1209
10761
1.15
4.54
2.7
2.7
674.56
694.96
ng/l
0.10
1007
8863
6595
65430
1.54
4.41
21.8
19.4
269.99
269.33
e9/l
0.38
6513
64585
1325
11897
1.14
4.37
4.0
3.8
—
—
—
0
0
848
7380
1.17
4.29
2.0
1.9
—
—
—
0
0
472
3895
1.23
4.28
4.0
3.3
81.10
75.24
ng/l
0.73
429
3448
847
7376
1.17
4.25
1.7
1.7
1189.01
1184.08
nmol/l
0.06
698
5800
763
6589
1.18
4.24
2.1
2.2
383.11
376.47
nmol/l
0.41
721
6125
308
2427
1.28
4.18
3.0
2.0
1.14
1.18
g/l
1.73
295
2327
332
2641
1.27
4.18
1.6
1.6
0.25
0.29
mg/l
0.65
151
1065
319
2532
1.27
4.09
1.4
1.3
37.11
33.91
u/ml
0.12
31
167
222
1680
1.33
4.06
1.3
1.4
322.76
305.46
ug/g
0.62
133
868
3885
37178
1.11
4.04
3.5
3.3
74.33
72.54
ug/l
0.39
3729
35531
6009
59014
1.18
3.99
4.9
4.7
2.85
2.87
mmol/l
1.37
5760
56446
474
3951
1.21
3.91
4.1
3.6
5.88
5.81
kpa
0.89
466
3837
73
450
1.63
3.86
4.1
2.7
13.34
14.11
index
0.32
47
270
429
3554
1.22
3.78
1.1
1.1
—
—
—
0
0
243
1884
1.30
3.77
1.3
1.3
—
—
—
0
0
451
3764
1.21
3.69
7.1
7.0
1.12
1.23
mmol/l
2.14
442
3694
1705
15691
1.12
3.69
2.3
2.3
2.61
2.61
mg/l
0.00
1500
13720
34
168
2.03
3.68
1.3
1.3
—
—
—
0
0
5942
58357
1.16
3.68
4.4
4.3
1.56
1.55
mmol/l
0.70
5701
55835
221
1701
1.31
3.63
2.4
2.3
—
—
—
0
0
472
3965
1.20
3.62
4.1
3.6
7.38
7.38
ph
0.03
259
2138
15
51
2.95
3.57
1.1
2.2
39.55
31.98
mg/mmol
0.14
15
43
225
1741
1.30
3.56
8.7
7.7
—
—
—
0
0
650
5627
1.17
3.53
3.3
3.6
4.53
4.52
pmol/l
0.06
578
5130
456
3828
1.21
3.53
4.2
3.6
1.78
1.79
mmol/l
0.02
403
3361
587
5040
1.18
3.53
1.2
1.2
—
—
—
0
0
3128
29740
1.10
3.49
2.7
2.6
—
—
estimate
—
0
0
76
490
1.56
3.38
2.1
2.7
21.86
24.70
mg/l
0.35
51
344
150
1105
1.37
3.34
3.7
3.3
36.83
40.32
mg/l
0.25
132
952
1031
9264
1.13
3.33
2.8
2.3
14.59
14.24
umol/l
0.80
985
8694
150
1107
1.36
3.31
3.7
3.3
28.56
36.84
mg/l
1.08
133
953
268
2145
1.26
3.28
1.6
1.6
4.65
9.87
iu/ml
—
6
63
325
2660
1.23
3.26
1.2
1.2
—
—
—
0
0
288
2327
1.25
3.25
1.4
1.3
15.75
6.36
u/ml
0.78
39
221
722
6350
1.15
3.20
1.2
1.2
—
—
—
0
0
49
287
1.71
3.20
2.3
2.0
9.47
9.70
mg/l
0.10
43
244
1940
18099
1.10
3.16
2.9
2.8
21.29
73.25
ng/l
0.80
897
8705
287
2330
1.24
3.12
1.4
1.4
16.50
8.18
u/ml
0.85
51
354
180
1379
1.31
3.11
2.4
2.1
426.26
491.83
ug/l
0.11
163
1254
34
180
1.89
3.08
1.5
4.3
61.00
932.03
mg/l
0.49
28
126
27
132
2.05
3.06
4.7
5.1
—
—
—
0
0
786
6981
1.14
3.04
2.2
2.0
29.28
28.91
s
0.78
768
6764
381
3195
1.20
3.02
1.4
1.3
—
—
—
0
0
3331
31890
1.09
3.01
4.7
4.2
6.25
6.32
mmol/l
0.87
3113
29313
220
1740
1.27
3.00
2.2
1.8
1.44
1.44
g/l
0.00
196
1515
31
161
1.93
2.98
2.1
2.0
1.53
3.81
ug/l
0.74
18
97
250
2012
1.25
2.95
1.1
1.1
—
—
—
0
0
321
2654
1.22
2.95
1.2
1.2
—
—
—
0
0
12
37
3.25
2.93
1.0
1.8
—
—
—
0
0
903
8117
1.13
2.90
1.4
1.3
26.17
26.37
iu/l
0.06
777
7075
432
3682
1.19
2.88
2.2
1.9
—
—
—
0
0
480
4128
1.18
2.87
1.1
1.1
311.36
216.23
titre
0.21
11
109
446
3814
1.18
2.86
2.0
1.9
1.47
1.34
g/l
0.32
419
3548
130
963
1.36
2.85
3.5
3.2
1.32
2.95
ratio
2.16
76
543
347
2905
1.21
2.82
2.4
2.4
—
—
—
0
0
253
2051
1.24
2.82
1.3
1.3
—
—
—
0
0
462
3969
1.18
2.81
1.4
1.4
218.36
236.01
miu/ml
0.53
241
2050
935
8449
1.12
2.76
2.8
2.3
2.41
2.46
g/l
2.02
869
7836
5378
52688
1.11
2.72
17.2
15.0
13.37
13.39
%
0.31
5330
52067
280
2307
1.22
2.69
8.8
9.0
24.40
24.25
mmol/l
0.38
271
2272
235
1905
1.24
2.64
2.7
2.4
3.57
3.62
g/l
0.20
228
1801
30
163
1.84
2.56
1.8
1.4
7.65
7.83
mmol/l
0.07
30
163
36
208
1.73
2.53
1.8
1.7
119.66
143.38
au/ml
—
7
31
382
3262
1.18
2.52
3.3
3.1
4.43
4.59
kpa
0.92
371
3162
55
356
1.55
2.50
2.5
2.7
—
—
—
0
0
179
1418
1.27
2.47
1.3
1.2
300.06
264.40
u/ml
0.89
127
922
532
4676
1.15
2.43
2.7
2.2
0.22
0.22
g/l
0.07
508
4408
246
2025
1.22
2.42
1.3
1.3
39.08
41.41
u/ml
0.09
24
201
65
440
1.48
2.41
2.9
2.8
55.20
56.39
%
0.23
54
380
1750
16430
1.09
2.40
3.6
3.3
7.16
7.30
mmol/l
0.59
1509
14300
230
1883
1.23
2.39
1.4
1.3
1.81
3.25
u/ml
0.63
23
118
5
8
6.25
2.37
1.0
1.0
—
—
—
0
0
118
891
1.33
2.35
2.3
2.2
—
—
—
0
0
2192
20794
1.08
2.32
8.9
8.2
1.10
1.10
inr
0.17
1792
17069
458
4000
1.16
2.30
2.1
1.9
—
—
—
0
0
460
4019
1.16
2.30
2.1
1.8
—
—
—
0
0
79
562
1.41
2.28
1.6
1.9
22.12
26.05
mg/l
0.39
33
210
1488
13901
1.09
2.28
2.5
2.1
295.61
298.83
umol/l
0.75
1347
12644
184
1479
1.25
2.28
4.0
2.8
1.40
1.32
mg/l
0.87
174
1380
461
4033
1.15
2.27
2.2
1.9
—
—
—
0
0
99
737
1.35
2.19
1.5
1.5
—
—
—
0
0
183
1480
1.24
2.16
3.3
3.4
212.51
362.68
u/ml
0.35
153
1259
155
1230
1.27
2.16
1.3
1.2
2.53
3.69
u/ml
2.08
74
531
299
2540
1.19
2.15
2.8
2.9
1.02
1.02
ratio
1.32
259
2216
286
2424
1.19
2.11
2.2
1.9
20.36
20.22
s
0.18
253
2067
454
3991
1.15
2.11
2.2
1.8
—
—
—
0
0
30
175
1.72
2.09
2.0
1.5
—
—
—
0
0
828
7556
1.11
2.08
3.0
2.4
23.93
23.33
%
0.69
781
7035
45
292
1.54
2.07
1.8
2.4
153.30
158.99
umol/l
0.05
27
154
516
4589
1.13
2.02
3.5
3.5
7.36
7.35
ph
0.16
380
3253
12
50
2.40
2.02
1.0
1.1
1.50
1.43
umol/24h
0.14
12
50
88
653
1.35
2.01
1.1
1.2
—
—
—
0
0
9
32
2.81
2.00
1.0
1.7
—
—
—
0
0
174
1415
1.24
1.98
1.4
1.3
—
—
—
0
0
54
369
1.47
1.97
3.0
2.7
104.37
49.17
mg/l
0.36
34
252
347
3009
1.16
1.96
1.6
1.6
9.52
11.05
u/ml
0.36
92
804
120
937
1.29
1.93
1.4
1.3
—
—
—
0
0
128
1008
1.28
1.93
2.5
2.6
10.13
27.95
iu/ml
—
7
57
557
4995
1.13
1.92
5.0
4.7
0.19
0.24
%
0.09
129
1016
505
4504
1.13
1.91
3.7
3.9
20.71
24.03
ug/l
0.08
382
3330
699
6358
1.11
1.88
2.2
2.2
4181.25
6182.05
u/l
0.90
259
2644
434
3838
1.14
1.88
8.0
7.8
96.00
96.22
%
0.27
417
3700
47
316
1.49
1.87
2.3
1.9
—
—
—
0
0
85
636
1.34
1.87
1.4
1.5
—
—
—
0
0
85
636
1.34
1.87
1.4
1.5
—
—
—
0
0
85
636
1.34
1.87
1.4
1.5
—
—
—
0
0
85
636
1.34
1.87
1.4
1.5
—
—
—
0
0
768
8379
0.91
1.85
1.5
1.6
1103.48
1016.63
mu/l
1.04
627
6995
2038
19424
1.07
1.83
3.0
2.9
0.89
0.08
estimate
0.75
597
5800
161
1312
1.23
1.83
1.4
1.3
153.56
155.72
au/ml
0.09
48
348
199
1658
1.21
1.82
2.5
2.2
9.99
10.77
mg/l
0.90
193
1571
29
176
1.65
1.78
1.2
1.1
—
—
—
0
0
103
804
1.29
1.70
2.9
2.7
32.82
32.74
umol/l
0.01
98
742
771
7098
1.10
1.65
1.2
1.2
140.14
146.05
u/ml
0.16
283
2911
31
196
1.58
1.65
1.0
1.1
5.11
5.35
mg/g
0.17
31
189
37
244
1.52
1.64
1.9
2.3
0.19
0.18
e9/l
0.10
15
115
70
521
1.35
1.63
1.3
1.3
15.56
63.15
u/ml
—
5
43
55
394
1.40
1.62
3.2
3.5
0.74
0.80
nmol/l
0.60
43
314
139
1135
1.23
1.59
1.5
1.5
0.64
0.62
g/l
0.07
112
880
536
4867
1.11
1.53
4.7
4.5
0.09
0.14
%
0.68
124
1054
889
8271
1.09
1.52
2.7
2.9
4.49
4.21
e9/l
0.35
808
7411
553
5036
1.11
1.50
4.6
4.5
0.77
0.90
%
0.30
141
1225
91
713
1.28
1.50
1.1
1.2
33.24
36.00
mg/l
0.39
80
607
187
1584
1.19
1.48
1.5
1.4
21853.41
1308.58
e6/l
0.48
141
1250
370
3297
1.13
1.48
2.5
2.5
66.32
67.24
g/l
1.40
338
3064
191
1622
1.18
1.47
2.9
3.0
623.00
364.33
mg/l
0.38
79
643
495
4488
1.11
1.47
7.7
7.3
7.42
7.42
ph
0.84
247
2398
17
94
1.81
1.47
1.1
1.1
0.53
0.65
umol/24h
0.75
12
49
71
540
1.32
1.46
1.1
1.1
—
—
—
0
0
184
1560
1.18
1.45
1.4
1.3
50.93
26.93
e6/l
0.51
134
1158
29
187
1.55
1.45
1.5
2.2
7.79
8.36
mmol/l
0.43
29
187
74
569
1.30
1.42
1.8
1.6
—
—
—
0
0
88
694
1.27
1.40
1.2
1.2
—
—
—
0
0
42
296
1.42
1.39
2.5
2.6
—
—
—
0
0
34
230
1.48
1.38
1.1
1.1
28.06
27.82
s
0.09
34
230
527
4815
1.10
1.36
4.5
4.3
0.70
0.70
%
0.00
139
1177
479
5256
0.90
1.34
3.5
3.5
—
—
—
0
0
0
37
0.00
1.34
0.0
7.7
—
—
—
0
0
57
754
0.75
1.33
1.1
1.2
4509.65
1951.13
pmol/l
0.27
11
60
178
1518
1.18
1.33
2.8
2.2
2.85
2.81
g/l
0.18
165
1412
12
61
1.97
1.32
1.2
1.3
—
—
—
0
0
16
271
0.59
1.31
1.1
1.1
—
3.81
—
0
16
85
675
1.26
1.30
1.0
1.1
6.28
7.85
iu/ml
0.38
26
199
28
415
0.67
1.29
10.1
14.2
779.00
3940.56
nmol/l
0.51
28
401
38
267
1.43
1.29
2.1
2.5
199.83
147.02
au/ml
—
6
41
53
702
0.75
1.27
2.2
2.7
7.07
7.25
mmol/l
0.20
53
681
20
122
1.64
1.27
2.1
1.5
—
—
—
0
0
499
4567
1.10
1.26
3.1
2.5
1.78
1.75
%
0.29
450
4102
1666
15952
1.06
1.26
4.4
4.2
—
—
—
0
0
487
4453
1.10
1.26
7.6
7.2
0.87
0.81
mmol/l
0.12
400
3609
30
203
1.48
1.24
29.6
26.5
113.48
107.03
ug/l
0.22
25
168
408
3703
1.11
1.23
8.6
8.1
117.89
120.35
g/l
1.93
400
3613
62
477
1.30
1.22
3.4
2.6
205.85
232.98
e6/l
0.59
53
387
163
1393
1.17
1.22
1.2
1.1
—
—
—
0
0
489
4481
1.10
1.22
7.6
7.3
13.60
13.61
kpa
0.01
468
4315
53
399
1.33
1.21
2.6
3.1
—
—
—
0
0
60
460
1.31
1.21
1.7
1.3
—
—
—
0
0
38
271
1.40
1.21
2.7
2.7
—
—
—
0
0
85
682
1.25
1.21
2.8
2.9
1.26
1.49
%
0.27
78
620
80
638
1.26
1.20
1.2
1.2
—
—
—
0
0
89
719
1.24
1.19
1.4
1.5
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
481
4411
1.10
1.18
1.4
1.6
291.06
313.08
mu/l
0.79
438
3922
2721
27994
0.95
1.18
2.5
2.6
—
—
—
0
0
28
189
1.48
1.18
1.1
1.1
—
—
—
0
0
8
38
2.11
1.18
1.0
1.1
—
—
—
0
0
77
613
1.26
1.17
3.1
2.5
1269.63
1349.93
e6/l
0.38
68
520
71
560
1.27
1.17
1.0
1.0
—
—
—
0
0
488
4482
1.10
1.17
7.6
7.3
5.05
5.05
kpa
0.02
469
4322
86
695
1.24
1.16
1.0
1.1
196.65
211.83
mg/l
0.80
79
621
59
455
1.30
1.16
3.0
2.6
581.04
515.90
e6/l
0.54
50
353
127
1069
1.19
1.15
1.3
1.2
33.21
12.23
u/ml
0.84
14
46
90
734
1.23
1.12
1.4
1.4
2.80
2.96
g/l
0.46
70
522
18
111
1.62
1.11
1.1
1.2
361.28
315.51
pmol/l
0.19
18
78
31
436
0.71
1.11
11.1
19.4
1257.23
3677.17
nmol/l
0.57
31
419
90
735
1.23
1.11
1.4
1.4
0.38
0.37
g/l
0.17
70
522
47
354
1.33
1.10
1.1
1.1
4.29
7.85
u/ml
—
9
65
155
1334
1.17
1.09
1.2
1.2
—
—
—
0
0
21
137
1.53
1.05
1.0
1.0
—
—
—
0
0
181
1584
1.15
1.03
2.7
2.1
3.33
3.64
g/l
3.46
168
1479
181
1585
1.15
1.02
2.7
2.2
4.14
4.33
g/l
3.00
168
1478
181
1587
1.14
1.01
2.7
2.2
7.20
7.29
g/l
0.34
168
1480
1197
11429
1.06
1.01
1.5
1.5
—
—
—
0
0
111
1311
0.84
1.01
6.0
5.2
1.14
1.24
mmol/l
0.87
99
1152
39
290
1.35
1.01
3.0
3.2
8.42
8.67
mg/l
0.09
31
226
101
845
1.20
1.01
1.4
1.5
—
—
—
0
0
75
609
1.23
1.00
1.1
1.2
64.41
57.18
nmol/l
0.54
75
602
1444
13862
1.05
1.00
3.8
3.4
49.80
44.87
mg/l
0.32
835
8194
89
736
1.21
1.00
1.4
1.4
7.79
6.41
g/l
2.08
69
525
134
1150
1.17
1.00
1.2
1.1
120.96
118.53
%
0.47
123
1054
10
175
0.57
0.98
1.1
1.2
—
52.20
—
0
5
87
720
1.21
0.98
4.5
6.0
380.90
374.00
umol/l
0.16
73
626
0
29
0.00
0.97
0.0
1.0
—
0.21
—
0
21
69
558
1.24
0.96
1.2
1.3
0.57
0.65
ratio
1.12
37
343
92
768
1.20
0.95
1.2
1.2
0.16
0.20
nmol/l
0.82
70
555
356
3262
1.10
0.94
3.0
2.6
69.48
71.90
e9/l
0.65
257
2300
20
133
1.51
0.94
1.2
1.2
—
—
—
0
0
11
62
1.78
0.94
1.1
1.1
90.18
83.10
titre
0.12
11
62
295
2679
1.11
0.94
2.0
2.1
4.96
5.33
ug/l
0.23
260
2347
55
435
1.27
0.93
2.9
3.0
9.52
10.62
mmol/l
2.01
55
426
89
1060
0.84
0.91
2.1
2.3
—
—
—
0
0
53
666
0.79
0.91
1.1
1.3
0.85
1.38
u/ml
0.40
26
362
6
28
2.14
0.91
1.3
1.4
—
—
—
0
0
1458
14037
1.05
0.91
4.3
4.0
9.58
8.35
mg/mmol
0.41
834
8288
154
1349
1.14
0.90
2.6
2.1
9.35
10.17
g/l
1.65
140
1234
271
2457
1.11
0.90
2.2
2.2
3.09
6.06
iu/l
0.81
123
1125
276
2506
1.11
0.89
2.3
2.2
—
—
—
0
0
133
1154
1.16
0.89
1.2
1.1
—
—
—
0
0
5
105
0.48
0.88
1.0
1.1
—
—
—
0
0
78
649
1.20
0.86
2.3
1.7
—
—
—
0
0
27
368
0.73
0.85
1.2
1.1
—
—
—
0
0
817
8594
0.94
0.84
1.3
1.3
—
—
—
0
0
200
1793
1.12
0.83
1.3
1.3
462.65
463.81
mg/l
0.01
192
1722
270
2460
1.10
0.83
3.1
3.1
128.36
129.76
g/l
0.57
265
2388
271
2470
1.10
0.83
1.4
1.5
71.12
109.84
pmol/l
2.66
265
2413
134
1172
1.15
0.82
2.0
2.0
5.18
5.41
mmol/24h
0.37
128
1070
111
959
1.16
0.81
1.8
2.1
—
—
—
0
0
12
188
0.64
0.79
1.1
1.1
0.09
2.67
u/ml
0.49
12
188
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
30
225
1.33
0.77
1.8
2.5
169.97
161.59
nmol/l
0.20
30
201
132
1161
1.14
0.76
1.8
1.7
8032.48
8116.79
e6/l
0.02
100
821
57
692
0.82
0.75
1.1
1.0
0.23
1.53
u/ml
1.54
19
214
37
288
1.29
0.75
1.1
1.2
65.78
70.06
ug/l
0.22
37
288
144
1276
1.13
0.75
1.2
1.2
—
—
—
0
0
12
75
1.60
0.74
3.1
2.2
—
—
—
0
0
198
2189
0.90
0.74
1.2
1.1
2.16
1.90
u/ml
0.18
90
1100
5
24
2.08
0.74
1.0
1.0
—
—
—
0
0
78
918
0.85
0.74
3.7
3.7
—
—
—
0
0
725
7615
0.95
0.73
1.5
1.6
3.46
3.47
mmol/l
0.11
486
4992
5350
53036
1.04
0.73
18.0
15.6
331.87
331.61
g/l
1.54
5327
52772
29
219
1.33
0.73
2.4
2.0
17.12
15.81
umol/l
0.33
29
219
172
1544
1.12
0.73
1.1
1.1
17.65
14.79
au/ml
0.17
44
455
43
343
1.26
0.72
3.6
2.8
293.16
216.06
e6/l
0.22
43
336
242
2214
1.10
0.71
10.0
9.0
15.69
16.03
%
1.14
234
2123
121
1064
1.14
0.71
1.5
1.3
42.83
61.65
u/ml
—
9
69
178
1604
1.11
0.71
1.3
1.2
3.47
3.59
mmol/l
1.38
171
1523
646
6138
1.06
0.69
4.2
4.0
32.20
32.82
%
0.80
473
4481
194
1759
1.11
0.69
1.1
1.1
—
—
—
0
0
194
1760
1.11
0.69
1.1
1.1
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
—
—
—
0
0
12
77
1.56
0.68
1.8
2.6
—
—
—
0
0
62
520
1.19
0.67
1.1
1.1
—
0.30
—
0
8
49
402
1.22
0.66
1.5
1.5
9088.86
87136.85
e6/l
1.88
35
269
147
1637
0.90
0.66
1.1
1.1
1.40
4.17
u/ml
3.37
57
774
126
1122
1.13
0.64
1.1
1.1
—
—
—
0
0
527
5556
0.94
0.63
1.4
1.5
—
—
—
0
0
94
822
1.15
0.63
1.6
1.4
405.80
563.12
pmol/l
0.60
84
727
46
378
1.22
0.62
1.5
1.7
1.86
3.07
nmol/l
0.91
38
300
63
534
1.18
0.62
1.1
1.2
—
—
—
0
0
5
30
1.67
0.61
1.2
1.2
—
1.11
—
0
7
54
453
1.19
0.60
1.5
1.6
5.91
6.02
mmol/l
0.12
42
360
0
20
0.00
0.60
0.0
1.2
—
33.55
—
0
20
0
22
0.00
0.59
0.0
1.2
—
68.13
—
0
22
140
1549
0.90
0.58
1.1
1.1
0.95
3.71
u/ml
10.77
49
666
276
2571
1.08
0.57
3.2
2.9
5.05
5.13
kpa
1.29
262
2482
45
373
1.21
0.57
2.6
2.8
—
—
—
0
0
83
946
0.88
0.56
4.0
2.8
—
—
—
0
0
19
141
1.35
0.56
2.3
1.7
—
—
—
0
0
142
1566
0.90
0.56
5.5
5.0
0.83
0.91
%
2.08
136
1476
8
55
1.46
0.56
2.3
2.0
0.75
0.84
u/field
—
8
55
147
1334
1.10
0.55
3.2
2.8
24.82
24.78
mmol/l
0.07
138
1242
40
329
1.22
0.55
1.3
1.3
153.10
144.12
mmol/24h
0.46
40
329
121
1089
1.11
0.54
1.0
1.1
—
—
—
0
0
32
394
0.81
0.53
1.4
1.5
0.51
0.50
e9/l
0.08
32
394
58
674
0.86
0.53
1.0
1.0
0.48
1.01
u/ml
0.79
16
154
121
1091
1.11
0.52
1.4
1.4
1.20
1.40
nmol/l
1.26
113
937
27
214
1.26
0.52
1.2
1.2
—
—
—
0
0
167
1815
0.92
0.50
1.1
1.1
0.57
1.47
u/ml
3.26
66
871
71
809
0.88
0.50
7.8
6.7
105.51
105.43
mmol/l
0.05
65
727
100
896
1.12
0.49
2.2
1.7
80.82
55.10
mu/l
0.49
92
817
71
808
0.88
0.49
7.8
6.7
11.31
11.12
mmol/l
0.18
65
726
22
171
1.29
0.49
2.1
1.7
8.20
8.81
ug/l
0.31
22
171
23
180
1.28
0.49
4.0
3.0
31.38
27.67
umol/l
1.03
17
131
7
45
1.56
0.48
4.6
1.5
—
—
—
0
0
22
172
1.28
0.48
1.2
1.2
—
—
—
0
0
277
2608
1.06
0.46
1.2
1.3
14.22
12.20
u/l
1.21
228
2151
35
418
0.84
0.45
1.1
1.1
38.80
13.02
u/ml
—
5
49
55
477
1.15
0.45
2.5
2.5
1.54
1.22
g/24h
0.45
29
272
36
301
1.20
0.45
1.1
1.2
—
—
—
0
0
76
675
1.13
0.45
1.2
1.1
20.83
15.58
u/ml
0.68
34
322
21
165
1.27
0.44
1.6
2.3
16.86
15.94
%
0.83
21
165
41
481
0.85
0.44
7.1
7.0
21.79
62.80
ug/l
0.59
27
322
146
1345
1.09
0.44
1.1
1.1
—
—
—
0
0
50
432
1.16
0.44
1.3
1.4
—
—
—
0
0
29
238
1.22
0.43
3.1
2.2
30.07
29.40
%
0.09
29
238
24
194
1.24
0.41
1.1
1.2
5.26
5.46
nmol/l
0.10
24
182
385
3675
1.05
0.41
1.1
1.1
—
—
—
0
0
111
1214
0.91
0.41
1.4
1.5
7.00
6.77
mmol/l
0.41
104
1103
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
69.00
—
0
11
37
314
1.18
0.41
1.0
1.1
—
—
—
0
0
32
268
1.19
0.40
1.3
1.2
—
—
—
0
0
16
123
1.30
0.40
1.0
1.1
—
—
—
0
0
78
867
0.90
0.40
4.8
2.9
2.01
2.39
mmol/l
0.60
47
557
60
530
1.13
0.40
1.1
1.1
301.40
298.04
mg/l
0.16
55
482
159
1478
1.08
0.40
1.5
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
4.25
—
0
7
0
19
0.00
0.39
0.0
1.1
—
11.64
—
0
12
126
1365
0.92
0.39
1.1
1.1
0.02
0.24
u/ml
1.71
32
382
21
169
1.24
0.38
1.0
1.1
7.09
6.30
u/ml
0.13
21
169
129
1395
0.92
0.38
4.0
4.0
39.47
28.08
u/ml
0.58
124
1352
75
832
0.90
0.38
5.3
4.8
36.81
91.03
u/ml
1.19
18
309
579
5594
1.04
0.37
1.3
1.3
130.83
184.10
u/ml
1.17
536
5215
177
1888
0.94
0.37
1.1
1.1
4.99
4.77
u/ml
0.08
81
982
62
553
1.12
0.37
1.8
1.7
52.90
50.27
%
0.20
42
328
48
421
1.14
0.36
1.0
1.1
0.30
4.15
nmol/l
1.22
13
68
43
492
0.87
0.36
7.1
4.0
7.20
7.27
mmol/l
0.02
33
414
272
2588
1.05
0.35
1.8
1.8
—
—
—
0
0
25
208
1.20
0.35
1.1
1.1
38.76
28.30
iu/ml
0.39
25
208
87
794
1.10
0.35
2.7
2.5
75.66
77.19
ug/min
0.02
54
490
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
77
847
0.91
0.34
1.1
1.1
—
—
—
0
0
172
1617
1.07
0.34
1.2
1.2
—
—
—
0
0
105
971
1.08
0.32
1.3
1.4
32.52
35.55
nmol/l
0.40
98
892
169
1792
0.94
0.31
1.1
1.1
0.41
0.98
u/ml
1.98
62
735
15
119
1.26
0.31
1.1
1.1
—
—
—
0
0
15
119
1.26
0.31
2.5
1.8
1062.40
25548.75
e6/l
—
10
55
435
4505
0.96
0.31
1.4
1.5
—
—
—
0
0
965
9866
0.97
0.31
1.7
1.8
3.28
3.27
ratio
0.16
709
7151
224
2354
0.95
0.31
1.5
1.5
0.36
0.48
nmol/l
2.00
186
1853
97
897
1.08
0.30
1.2
1.3
0.49
3.77
nmol/l
0.80
97
873
7
53
1.32
0.30
3.6
2.8
—
—
—
0
0
14
174
0.80
0.29
1.1
1.1
—
—
—
0
0
14
174
0.80
0.29
1.1
1.1
—
—
—
0
0
14
174
0.80
0.29
1.1
1.1
—
—
—
0
0
53
477
1.11
0.29
1.3
1.4
12.31
9.98
umol/l
1.05
53
449
466
4810
0.97
0.29
1.5
1.5
68.33
60.69
ug/l
1.19
377
3991
260
2489
1.05
0.29
3.2
2.9
7.42
7.42
ph
1.02
212
2071
388
4017
0.96
0.29
3.9
3.2
1.22
1.23
mmol/l
2.10
338
3478
14
112
1.25
0.28
1.4
1.6
—
—
—
0
0
60
546
1.10
0.27
1.1
1.1
—
—
—
0
0
241
2307
1.05
0.27
1.3
1.3
—
—
—
0
0
10
77
1.30
0.26
1.1
1.2
—
—
—
0
0
28
320
0.87
0.25
1.1
1.1
—
—
—
0
0
10
127
0.79
0.25
2.9
1.8
—
—
—
0
0
36
320
1.13
0.25
1.1
1.1
—
—
—
0
0
40
445
0.90
0.24
3.2
3.3
—
—
—
0
0
40
359
1.11
0.24
1.1
1.1
—
—
—
0
0
12
96
1.25
0.24
1.1
1.0
0.03
0.03
u/ml
0.11
12
96
10
78
1.28
0.24
1.1
1.0
0.44
0.08
u/ml
—
5
37
48
436
1.10
0.24
1.5
1.6
1.15
1.15
promille
0.00
40
341
19
161
1.18
0.24
3.2
1.6
—
—
—
0
0
58
631
0.92
0.24
1.0
1.0
0.17
0.28
u/ml
0.52
13
131
27
237
1.14
0.23
1.1
1.1
—
—
—
0
0
443
4551
0.97
0.23
1.4
1.5
1.20
1.15
ratio
0.47
248
2775
23
264
0.87
0.23
1.1
1.1
—
—
—
0
0
5
40
1.25
0.22
1.4
1.1
—
14.16
—
0
11
127
1205
1.05
0.22
1.6
1.5
—
—
—
0
0
196
1881
1.04
0.22
1.3
1.3
154.71
133.87
titre
0.10
17
186
40
362
1.11
0.22
1.5
1.8
1.98
1.93
umol/l
0.21
35
329
22
252
0.87
0.21
1.0
1.1
—
—
—
0
0
24
273
0.88
0.21
1.1
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
127.20
—
0
5
275
2660
1.04
0.21
2.3
2.6
164.26
120.20
ng/l
0.79
243
2396
138
1448
0.95
0.21
2.7
3.2
59.29
57.89
%
0.92
138
1448
13
156
0.83
0.21
1.2
1.0
—
—
—
0
0
13
156
0.83
0.21
1.2
1.0
—
—
—
0
0
13
156
0.83
0.21
1.2
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.19
—
0
6
48
440
1.09
0.21
1.3
1.2
10.25
9.47
mm/h
0.16
48
440
0
13
0.00
0.21
0.0
1.0
—
0.05
—
0
13
0
13
0.00
0.21
0.0
4.8
—
1.41
—
0
13
22
251
0.88
0.20
1.2
1.1
0.31
2.80
u/ml
1.76
16
137
114
1082
1.05
0.20
1.8
2.0
126.61
130.20
g/l
1.05
82
861
46
501
0.92
0.20
1.4
1.6
90.65
90.61
%
0.02
46
495
0
14
0.00
0.20
0.0
2.1
—
0.55
—
0
14
0
14
0.00
0.20
0.0
6.3
—
351.50
—
0
14
13
108
1.20
0.20
1.3
1.3
—
—
—
0
0
6
49
1.22
0.20
1.2
1.1
6.42
13.04
pmol/l
—
6
49
97
1025
0.95
0.20
1.1
1.2
97.15
11535.04
iu/ml
0.63
23
233
6
50
1.20
0.19
1.2
1.4
19.67
19.90
%
—
6
41
26
231
1.13
0.19
1.0
1.0
263.22
335.34
ng/l
1.41
18
177
26
231
1.13
0.19
1.1
1.2
—
0.29
g/l
—
0
11
75
798
0.94
0.19
3.9
3.5
155.12
685.47
u/ml
0.83
68
722
10
81
1.23
0.18
1.1
1.2
—
—
—
0
0
235
2276
1.03
0.18
1.1
1.1
7.26
5.40
eliau/ml
0.15
46
362
166
1725
0.96
0.18
4.8
4.7
1.71
1.66
%
0.23
157
1630
91
960
0.95
0.18
4.3
2.5
0.82
0.87
nmol/l
0.37
77
826
17
147
1.16
0.18
1.4
1.5
—
—
—
0
0
43
396
1.09
0.18
1.2
1.1
—
—
—
0
0
2073
20907
0.99
0.18
1.6
1.7
—
—
—
0
0
240
2327
1.03
0.18
1.4
1.3
2.77
3.35
ug/l
1.39
215
2122
53
569
0.93
0.17
1.2
1.2
—
—
—
0
0
22
246
0.89
0.16
1.7
1.5
3.87
4.80
%
—
8
41
26
235
1.11
0.15
1.0
1.0
711.28
790.66
ng/l
0.32
18
175
23
255
0.90
0.15
1.4
1.4
—
—
—
0
0
47
502
0.94
0.14
1.1
1.1
1490.49
1533.81
miu/ml
0.11
47
502
7
87
0.80
0.14
1.1
1.1
—
—
—
0
0
137
1322
1.04
0.14
1.1
1.1
3.47
3.14
eliau/ml
0.13
77
721
16
181
0.88
0.14
4.4
3.1
171.06
82.60
ng/l
—
7
86
102
1062
0.96
0.13
3.5
3.4
17.43
22.58
mg/l
1.52
59
715
39
364
1.07
0.13
1.9
1.8
2.22
1.84
u/field
0.19
23
200
191
1861
1.03
0.12
1.3
1.3
773.75
1031.71
titre
—
8
82
53
502
1.06
0.12
1.3
1.5
5.25
5.22
mmol/l
0.09
48
481
69
659
1.05
0.12
1.1
1.1
—
—
—
0
0
364
3701
0.98
0.11
1.5
1.5
1.27
1.25
mm
0.32
259
2684
17
153
1.11
0.11
2.9
2.2
2.62
2.91
ug/l
0.16
17
128
235
2303
1.02
0.10
1.3
1.2
—
—
—
0
0
34
362
0.94
0.10
1.6
1.2
42.14
71.58
%
—
7
36
48
456
1.05
0.10
2.8
2.5
—
—
—
0
0
65
623
1.04
0.10
1.2
1.2
116.48
118.15
pmol/l
0.14
65
623
64
614
1.04
0.10
1.1
1.1
—
—
—
0
0
1133
11247
1.01
0.09
1.6
1.6
57101035.56
31392941.59
pmol/l
0.69
1014
9824
29
308
0.94
0.08
1.3
1.4
15170.14
2580.29
e6/l
0.46
21
213
10
113
0.88
0.08
5.9
2.0
—
—
—
0
0
7
64
1.09
0.08
1.6
1.6
—
—
—
0
0
13
117
1.11
0.08
2.2
1.5
2.66
3.18
mmol/l
0.56
13
110
77
746
1.03
0.08
1.6
1.4
57.11
64.41
mmol/l
0.95
65
589
17
156
1.09
0.08
3.1
2.2
2.89
3.01
ug/l
0.06
17
142
27
254
1.06
0.07
2.2
1.6
0.00
0.02
estimate
0.80
27
254
371
3754
0.99
0.07
1.5
1.5
—
—
—
0
0
8
75
1.07
0.07
1.0
1.4
—
261.49
—
0
8
55
530
1.04
0.07
1.1
1.1
1.07
1.05
ratio
0.41
47
439
137
1342
1.02
0.07
2.0
1.9
0.79
1.78
ug/l
2.36
120
1193
7
82
0.85
0.07
1.6
2.1
1.15
1.19
mmol/l
—
7
77
7
83
0.84
0.07
1.7
1.4
—
—
—
0
0
25
265
0.94
0.07
1.3
1.4
24465.43
73132.30
e6/l
0.73
14
132
572
5767
0.99
0.06
1.7
1.7
—
—
—
0
0
31
295
1.05
0.06
1.5
2.0
37.24
24.33
ug/l
0.78
31
290
15
138
1.09
0.06
1.0
1.1
—
208.00
—
0
10
33
315
1.05
0.06
1.6
1.4
—
—
—
0
0
27
256
1.05
0.06
1.1
1.1
10.00
221.72
ng/l
—
5
65
12
109
1.10
0.06
1.2
1.3
65.67
60.53
ug/l
0.59
12
109
44
424
1.04
0.06
1.6
1.6
32.84
39.12
%
0.57
31
232
228
2307
0.99
0.05
7.3
6.4
24.58
24.38
mmol/l
0.41
217
2198
18
169
1.07
0.05
1.3
1.2
—
—
—
0
0
32
308
1.04
0.04
1.2
1.5
72.22
221.60
nmol/24h
0.84
32
308
49
477
1.03
0.04
1.6
1.7
1.25
1.88
u/ml
0.59
13
122
57
557
1.02
0.03
1.2
1.3
—
—
—
0
0
13
121
1.07
0.03
1.0
1.2
7.45
7.43
ph
—
8
78
41
421
0.97
0.03
4.1
2.7
1479.49
718.37
u/ml
0.62
41
416
23
239
0.96
0.02
1.5
1.5
12.52
11.35
u/l
0.27
23
232
33
321
1.03
0.02
1.3
1.5
125.03
128.99
nmol/l
0.25
33
321
382
3837
1.00
0.02
1.5
1.6
—
—
—
0
0
33
339
0.97
0.02
1.0
1.1
18.29
9.64
u/ml
0.64
13
240
168
1667
1.01
0.02
3.2
2.9
25.60
25.44
mmol/l
0.28
161
1598
10
107
0.93
0.02
2.3
2.8
—
—
—
0
0
11
117
0.94
0.01
1.5
1.4
20.83
43.71
%
—
6
76
15
157
0.96
0.01
1.4
2.1
41.51
41.28
g/l
0.09
15
157
322
3210
1.00
0.01
1.1
1.1
0.56
0.59
ratio
0.29
27
348
40
407
0.98
0.01
1.7
1.4
5.16
5.05
u/l
0.07
29
360
10
106
0.94
0.01
1.1
1.1
—
—
—
0
0
26
254
1.02
0.00
1.5
1.4
—
—
—
0
0
37
376
0.98
0.00
1.4
1.4
68.38
68.34
umol/l
0.00
37
376
63
636
0.99
0.00
1.3
1.2
48.08
19.61
u/l
0.69
52
555
11
114
0.96
0.00
1.0
1.0
0.03
0.08
u/ml
—
6
67
14
144
0.97
0.00
1.1
1.1
—
—
—
0
0
46
463
0.99
0.00
1.9
2.1
0.86
0.90
%
0.12
27
272
17
166
1.02
0.00
1.2
1.3
155.83
118.55
nmol/l
0.25
12
127
50
497
1.01
0.00
1.2
1.3
1069.23
1051.14
titre
0.04
13
88
27
266
1.02
0.00
1.4
1.5
—
—
—
0
0
17
175
0.97
0.00
1.1
1.0
0.04
1.08
u/ml
0.93
12
109
22
225
0.98
0.00
2.3
1.9
—
—
—
0
0
28
275
1.02
0.00
1.6
1.6
1.89
2.72
u/field
0.23
18
196
53
525
1.01
0.00
3.9
2.8
—
—
—
0
0
13
128
1.02
0.00
1.2
1.3
5.45
5.61
mmol/l
0.35
13
128
24
242
0.99
0.00
2.3
2.2
1.53
1.12
ug/l
0.36
24
231
194
1936
1.00
0.00
2.1
2.2
4.53
5.24
umol/l
0.69
145
1416
11
111
0.99
0.00
2.4
1.5
—
—
—
0
0
23
229
1.00
0.00
1.3
1.2
16.83
10.66
%
—
6
29
53
531
1.00
0.00
1.3
1.6
280.98
279.29
mosm/kgh2o
0.20
43
418
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
9
95
0.95
0.00
1.1
1.3
—
99.48
—
0
5
7
79
0.89
0.00
1.0
1.0
0.14
0.16
u/ml
—
7
72
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.0
1.1
—
3.50
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.71
—
0
5
5
51
0.98
-0.00
1.0
1.2
0.16
0.16
umol/l
—
5
51
5
51
0.98
-0.00
4.6
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
8
84
0.95
-0.00
1.7
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
308.80
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_FEMALE_GENITAL_LSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_FEMALE_GENITAL_LSIL 1.019 [0.91, 1.15] 0.75
Birth year 0.991 [0.98, 1.0] 0.052

During the follow-up period (1.1.1998 — 31.12.2019), 1028 out of 27266 females with N14_FEMALE_GENITAL_LSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_FEMALE_GENITAL_LSIL.

N-year risk Females Males
1 0.107% No data
5 0.611% No data
10 1.459% No data
15 2.814% No data
20 4.773% No data

Relationships between endpoints

Index endpoint: N14_FEMALE_GENITAL_LSIL – LSIL lesion of the cervix uteri, vagina or vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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