No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
647 |
4. Check minimum number of eventsNone |
647 |
5. Include endpointsNone |
647 |
6. Filter based on genotype QC (FinnGen only) |
587 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Similar endpoints
↥List of similar endpoints to
LSIL lesion of the vagina
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the vagina
- Other noninflammatory disorders of vagina
- LSIL lesion of the cervix uteri, vagina or vulva
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Noninflammatory disorders of female genital tract
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2429 | 2429 | - |
| Only index persons | 2363 | 2363 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.07 | - |
| Only index persons | 0.09 | 0.09 | - |
| Median age at first event (years) | |||
| Whole population | - | 50.78 | - |
| Only index persons | - | 50.56 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 587 | 587 | - |
| Unadjusted period prevalence (%) | 0.21 | 0.21 | - |
| Median age at first event (years) | 52.93 | 52.93 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 607
- Matched controls
- 6070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LEB00
NOMESCO Finland
Biopsy of vagina
125.4
307.7
340
61
ULA02
NOMESCO Finland
Kolposcopy
59.7
307.7
520
552
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
33.2
307.7
469
564
N89.0
ICD-10 Finland
Mild vaginal dysplasia
+∞
307.7
607
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
165.7
303.6
150
12
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
15.5
268.4
400
671
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
16.1
263.5
305
359
N87.0
ICD-10 Finland
Mild cervical dysplasia
25.8
256.5
198
112
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
20.7
180.9
149
94
A63.0
ICD-10 Finland
Anogenital (venereal) warts
17.2
174.2
160
124
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
22.9
165.5
128
70
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.2
143.8
178
216
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
11.7
141.1
168
193
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
284.6
75.2
75
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
102.0
66.5
72
8
N87.1
ICD-10 Finland
Moderate cervical dysplasia
9.4
56.9
72
86
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
17.7
55.3
46
28
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
9.8
51.0
62
70
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
271.9
49.8
50
*
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
108.8
46.5
50
5
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
7.6
45.4
68
99
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.7
31.1
337
1929
D06BB10
ATC
imiquimod; topical
4.8
30.3
73
167
L04AX01
ATC
azathioprine; systemic
5.1
23.8
52
109
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
21.7
22.8
33
16
G01AA10
ATC
clindamycin; vaginal
2.4
21.0
185
924
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
49.8
20.3
24
5
ZXC10
NOMESCO Finland
Use of laser
6.2
20.2
35
59
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
32.5
19.4
25
8
X86
ICPC
Abnormal cervix smear
7.8
17.1
24
32
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
34.4
15.8
20
6
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.0
14.1
419
3184
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
29.1
13.0
17
6
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.3
11.6
93
436
D06BB04
ATC
podophyllotoxin; topical
2.8
10.6
54
203
LCA06
NOMESCO Finland
Biopsy of endometrium
2.0
10.0
130
733
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
9.9
117
638
LEB10
NOMESCO Finland
Excision of lesion of vagina
12.5
9.9
17
14
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.5
9.4
63
272
ZXC00
NOMESCO Finland
Use of diathermy
10.3
9.1
17
17
L04AA06
ATC
mycophenolic acid; systemic
5.0
8.9
19
39
ULC02
NOMESCO Finland
Hysteroscopy
2.5
8.8
55
230
P01BA02
ATC
hydroxychloroquine; oral
2.2
8.4
74
359
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
4.9
8.2
18
38
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
6.4
8.1
20
32
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.2
8.0
71
347
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.0
7.9
35
122
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
7.4
45
185
R87.0
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal level of enzymes
20.3
7.1
10
5
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
12.2
7.1
12
10
L04AD02
ATC
tacrolimus; systemic
8.4
6.9
14
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
6.7
255
1914
N30.0
ICD-10 Finland
Acute cystitis
1.7
6.5
135
873
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
11.2
6.3
11
10
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
12.7
6.1
10
8
M05BA04
ATC
alendronic acid; oral
2.1
6.0
55
271
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
2.3
6.0
44
198
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
37
25.11
111.80
3.7
1.5
—
—
—
0
0
412
1594
5.93
99.73
3.0
1.5
—
—
—
0
0
162
362
5.74
71.90
2.9
1.5
—
—
—
0
0
145
770
2.16
13.50
2.2
1.9
—
—
—
0
0
148
840
2.01
11.33
2.4
2.0
—
—
—
0
0
107
563
2.09
9.98
2.0
1.8
—
—
—
0
0
65
287
2.42
9.22
4.4
1.8
19.01
7.08
iu/ml
1.04
20
72
115
653
1.94
8.60
4.6
4.4
32.44
32.72
%
0.10
70
441
89
463
2.08
8.50
1.8
1.7
—
—
—
0
0
490
4221
1.83
7.97
6.3
4.4
11.85
11.17
mm/h
0.64
454
3974
40
163
2.56
6.74
2.6
2.2
1.49
1.43
g/l
0.15
35
139
27
90
3.09
6.58
2.3
1.8
—
—
—
0
0
29
101
2.97
6.56
1.9
3.8
1.12
2.02
ratio
1.14
17
60
13
17
7.79
6.15
3.8
2.7
0.59
0.63
mmol/l
0.75
13
17
480
4225
1.65
5.87
11.7
7.6
78.95
76.31
u/l
0.52
451
4006
17
47
3.69
5.51
1.3
1.2
—
—
—
0
0
224
1701
1.50
5.29
3.5
2.4
57.60
60.79
u/l
0.44
210
1574
22
75
3.01
5.19
1.9
1.3
—
—
—
0
0
21
70
3.07
5.15
1.8
1.3
—
—
—
0
0
91
561
1.73
5.12
6.3
5.1
—
—
—
0
0
40
186
2.23
5.09
2.1
1.9
—
—
—
0
0
183
1341
1.52
5.08
2.7
2.1
—
—
—
0
0
22
76
2.97
5.08
1.9
1.3
—
—
—
0
0
22
76
2.97
5.08
1.9
1.3
—
—
—
0
0
342
2842
1.47
5.04
8.9
5.9
9.80
9.81
umol/l
0.01
327
2704
21
71
3.03
5.03
1.8
1.3
—
—
—
0
0
21
71
3.03
5.03
1.8
1.3
—
—
—
0
0
291
2349
1.46
4.96
7.8
5.4
1.22
1.22
mmol/l
0.30
257
2174
321
2657
1.44
4.69
8.9
6.1
1.22
1.22
mmol/l
0.07
275
2304
380
3246
1.46
4.69
13.5
9.3
3.77
3.91
e9/l
0.76
338
2841
179
1334
1.48
4.51
1.6
1.5
2.19
2.19
g/l
0.01
111
842
122
838
1.57
4.48
3.5
2.6
0.95
1.10
e6/l
0.18
65
406
12
23
5.30
4.47
1.5
1.1
—
—
—
0
0
12
23
5.30
4.47
1.5
1.1
—
—
—
0
0
11
19
5.87
4.46
1.5
1.1
—
—
—
0
0
11
19
5.87
4.46
1.5
1.1
—
—
—
0
0
31
139
2.30
4.32
2.8
2.7
1.78
2.16
index
0.14
18
70
36
172
2.16
4.32
2.0
1.8
—
—
—
0
0
26
108
2.47
4.28
17.0
5.0
496.89
163.00
iu/ml
—
9
11
416
3648
1.45
4.23
6.1
4.4
—
1489.79
—
0
47
92
600
1.63
4.19
8.7
4.5
1.03
1.04
mmol/l
0.08
83
542
67
402
1.75
4.15
1.4
1.3
25.56
42.84
au/ml
—
5
36
279
2287
1.41
4.12
6.4
4.2
36.61
36.55
g/l
0.07
261
2175
282
2324
1.40
4.00
2.1
2.0
101.62
99.43
pmol/l
0.33
141
1179
46
250
1.91
3.92
1.6
1.6
—
—
—
0
0
28
126
2.28
3.89
1.6
1.2
—
—
—
0
0
110
764
1.54
3.83
3.6
2.8
4.36
4.53
e6/l
0.05
50
333
14
39
3.65
3.72
1.4
1.4
—
—
—
0
0
326
2777
1.38
3.68
3.0
2.5
78.57
78.06
nmol/l
0.13
289
2567
40
213
1.94
3.63
1.6
1.2
14.03
1.97
u/ml
—
8
22
40
214
1.93
3.58
1.6
1.2
14.73
12.68
u/ml
—
10
42
37
193
1.98
3.56
1.6
1.5
0.01
0.02
iu/ml
—
5
21
34
172
2.03
3.56
1.2
1.3
—
—
—
0
0
12
31
3.93
3.50
1.8
2.2
824.33
501.64
e6/l
1.07
12
25
560
5288
1.76
3.49
15.0
12.5
85.43
85.24
ml/min/173m2
0.08
514
4855
202
1607
1.39
3.41
4.6
3.1
27.22
53.17
e6/l
1.21
158
1196
557
5257
1.72
3.41
5.3
4.7
5.64
5.75
mmol/l
1.98
505
4918
69
443
1.63
3.35
2.8
2.4
27.19
25.09
au/ml
—
8
41
9
19
4.79
3.25
1.1
1.9
—
—
—
0
0
9
19
4.79
3.25
1.1
1.9
—
—
—
0
0
34
179
1.95
3.21
1.6
1.3
—
—
—
0
0
178
1400
1.38
3.19
2.6
2.2
2.74
2.76
mg/l
0.07
147
1211
107
768
1.48
3.17
2.1
1.8
—
—
—
0
0
176
1383
1.38
3.17
4.3
2.9
0.30
0.37
e6/l
0.30
127
981
308
2643
1.34
3.11
3.0
2.5
—
—
estimate
—
0
0
143
1094
1.40
3.00
3.9
2.5
8.50
8.57
e6/l
0.01
135
998
5
5
10.07
2.98
1.0
2.2
—
—
—
0
0
592
5725
2.38
2.93
16.5
11.4
24.45
23.91
u/l
0.40
575
5592
18
76
2.41
2.92
4.1
2.8
25.89
31.59
umol/l
0.95
18
68
107
782
1.45
2.89
2.7
2.3
2.36
2.42
g/l
0.52
101
730
14
53
2.68
2.81
1.6
1.7
24.40
15.81
mg/l
—
5
20
8
18
4.49
2.80
2.9
2.1
52.88
51.16
ug/l
—
8
18
21
98
2.18
2.74
1.8
1.4
143.76
174.57
au/ml
—
5
29
157
1238
1.36
2.73
2.8
2.9
810.05
829.40
ng/l
0.03
133
1047
20
92
2.21
2.70
1.3
1.3
—
—
—
0
0
184
1489
1.34
2.69
1.8
1.6
22.39
21.65
nmol/l
0.24
158
1283
9
24
3.79
2.68
1.3
1.1
—
—
—
0
0
14
55
2.58
2.63
1.3
1.2
—
—
—
0
0
14
55
2.58
2.63
1.3
1.2
—
—
—
0
0
192
1570
1.33
2.60
1.3
1.3
0.62
1.85
u/ml
2.17
46
441
84
599
1.47
2.58
4.6
2.3
7.32
5.77
umol/l
0.28
76
524
18
81
2.26
2.56
1.7
1.3
—
—
—
0
0
7
17
4.15
2.36
1.6
1.1
—
—
—
0
0
52
342
1.57
2.34
2.0
1.6
—
—
—
0
0
441
4713
0.76
2.22
21.6
16.3
13.63
13.48
%
1.83
436
4657
7
19
3.71
2.15
1.3
1.1
—
—
—
0
0
29
167
1.77
2.15
3.0
1.9
188.14
170.47
%
0.70
29
159
336
3008
1.26
2.14
5.7
4.3
6.27
6.42
mmol/l
0.55
310
2811
425
3915
1.29
2.12
4.5
3.1
38.47
39.41
u/l
0.13
401
3732
30
176
1.74
2.10
1.5
1.2
54.80
46.32
u/ml
—
8
17
10
37
2.73
2.07
1.5
2.0
—
—
—
0
0
192
1614
1.28
2.05
5.3
3.8
0.02
0.01
estimate
0.31
59
598
9
32
2.84
2.00
3.2
2.0
95.22
103.25
%
—
9
32
332
2982
1.25
2.00
5.0
3.7
0.00
0.00
estimate
0.50
60
613
93
709
1.37
1.99
3.0
2.4
24.83
23.21
%
0.40
88
666
568
5485
1.55
1.93
18.2
14.4
3.92
3.92
mmol/l
0.01
553
5362
189
1597
1.27
1.92
2.6
2.1
102.38
181.55
u/l
1.24
180
1518
7
22
3.21
1.88
2.1
1.4
9.39
8.30
ug/l
—
7
22
213
1831
1.25
1.86
3.5
3.2
18.63
65.03
ng/l
0.67
131
1092
333
3008
1.24
1.84
5.1
3.7
0.00
4.65
estimate
0.80
58
627
53
371
1.47
1.83
1.7
2.6
66.20
67.61
g/l
0.63
46
347
5
12
4.19
1.82
1.8
1.2
—
—
—
0
0
13
60
2.19
1.79
1.5
1.1
—
—
—
0
0
18
95
1.92
1.77
1.2
1.1
2.50
5.46
u/ml
—
8
35
334
3027
1.23
1.76
5.1
3.8
0.00
0.02
estimate
1.08
58
600
55
391
1.45
1.76
3.1
2.3
0.18
0.58
e6/l
0.85
48
369
588
5738
1.79
1.75
22.0
16.6
68.21
67.57
umol/l
0.32
576
5678
200
1721
1.24
1.71
3.7
3.2
6.56
6.98
mmol/l
0.88
164
1471
51
360
1.45
1.70
1.0
1.1
—
—
—
0
0
59
430
1.41
1.66
4.5
3.7
4.52
4.63
pmol/l
0.42
52
383
73
553
1.36
1.64
2.0
1.8
—
—
—
0
0
104
831
1.30
1.63
5.0
3.0
0.81
0.82
mmol/l
0.50
94
784
10
42
2.40
1.62
2.2
1.6
—
—
—
0
0
10
42
2.40
1.62
3.8
3.2
28.30
16.47
mu/l
—
10
42
275
2458
1.22
1.62
2.0
1.9
1.31
1.33
mmol/l
0.18
238
2136
5
14
3.59
1.62
1.2
3.1
134.20
116.43
%
—
5
14
565
5474
1.46
1.61
17.9
14.3
139.61
139.77
mmol/l
0.79
550
5366
7
27
2.61
1.52
4.1
2.1
1.37
1.30
nmol/l
—
7
20
77
597
1.33
1.50
2.3
2.1
394.06
381.84
nmol/l
0.22
69
563
17
94
1.83
1.48
1.2
1.1
2.57
1.53
u/ml
—
7
32
10
45
2.24
1.47
1.0
1.0
313.60
295.12
mg/l
—
10
40
331
3031
1.20
1.47
3.6
3.2
85.70
80.51
ug/l
0.33
310
2871
27
173
1.59
1.42
1.2
1.8
2.77
2.92
g/l
0.37
22
165
74
933
0.76
1.37
2.9
3.4
186.22
222.33
ng/l
0.10
50
602
183
1593
1.21
1.37
4.2
3.9
17.34
8.76
mg/mmol
0.64
86
920
94
760
1.28
1.36
1.7
1.7
1030.99
1210.11
nmol/l
1.37
71
574
25
159
1.60
1.36
1.2
1.8
8.38
10.05
g/l
1.77
20
150
10
47
2.15
1.34
2.2
1.5
—
—
—
0
0
9
42
2.16
1.34
1.1
1.0
—
—
—
0
0
56
422
1.36
1.33
5.2
3.3
81.67
74.71
ng/l
0.22
50
379
48
354
1.39
1.30
1.8
1.5
—
—
—
0
0
6
133
0.45
1.29
1.7
1.5
41.47
56.19
ug/l
—
6
133
222
1981
1.19
1.26
5.5
3.0
28.26
28.67
u/l
0.12
213
1885
23
147
1.59
1.24
1.2
1.4
23.57
26.22
u/l
0.13
16
122
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
25
2.41
1.24
1.3
2.3
128.83
109.00
%
—
6
25
27
180
1.52
1.23
1.2
1.8
7.27
7.45
g/l
0.19
22
172
27
180
1.52
1.23
1.2
1.8
4.03
4.30
g/l
0.91
22
172
27
180
1.52
1.23
1.2
1.8
3.42
3.86
g/l
0.95
22
172
600
5929
2.04
1.22
28.2
20.7
4.38
4.44
e12/l
2.57
587
5820
600
5929
2.04
1.22
28.7
21.0
39.65
39.94
%
1.13
592
5882
600
5928
2.05
1.22
28.2
20.7
91.23
90.85
fl
1.35
593
5882
600
5927
2.07
1.22
28.3
20.8
270.54
265.72
e9/l
1.03
590
5833
5
19
2.64
1.22
2.2
3.2
0.80
1.82
%
—
5
19
561
5463
1.36
1.19
5.3
4.9
4.89
4.87
mmol/l
0.31
526
5170
600
5930
2.02
1.10
28.4
20.9
132.10
132.96
g/l
1.09
593
5884
8
41
1.96
1.09
2.5
2.2
—
—
—
0
0
15
89
1.70
1.08
1.3
1.1
—
—
—
0
0
14
82
1.72
1.06
1.4
1.3
733.86
332.93
mu/l
—
7
67
9
46
1.97
1.04
1.9
1.7
—
—
—
0
0
124
1068
1.20
1.03
1.6
1.6
467.63
30769673.87
pmol/l
1.31
109
923
54
423
1.30
1.03
5.5
3.2
5.94
5.78
kpa
0.52
54
415
217
1965
1.16
1.00
3.2
3.5
2.35
2.36
mmol/l
0.48
195
1814
56
443
1.29
1.00
2.9
2.3
69.83
72.54
ml/min/173m2
0.22
23
184
5
23
2.18
0.98
2.8
3.5
1.00
0.96
index
—
5
23
12
69
1.75
0.97
1.2
1.1
98.83
98.68
%
0.01
12
62
9
50
1.81
0.97
1.0
1.0
—
—
—
0
0
33
242
1.38
0.97
1.5
1.5
—
—
—
0
0
156
1380
1.18
0.96
1.8
1.7
1.08
0.96
mg/l
0.26
114
1069
6
27
2.23
0.93
1.8
2.7
178.00
180.41
u/l
—
6
27
12
70
1.73
0.93
1.2
1.0
—
—
—
0
0
65
530
1.25
0.92
1.9
1.8
—
—
—
0
0
30
402
0.73
0.89
1.3
1.6
970.90
997.19
mu/l
0.06
22
320
14
87
1.62
0.88
1.1
1.2
—
—
—
0
0
527
5125
1.21
0.87
6.0
5.6
37.28
38.15
mmol/mol
2.33
488
4856
61
498
1.25
0.86
1.3
1.3
215.36
162.61
u/ml
0.30
56
463
8
44
1.83
0.86
2.3
1.4
—
—
—
0
0
8
44
1.83
0.86
2.3
1.4
—
—
—
0
0
8
44
1.83
0.86
2.3
1.4
—
—
—
0
0
51
408
1.27
0.85
1.5
1.5
—
—
—
0
0
148
1318
1.16
0.84
3.8
2.4
302.58
307.55
umol/l
0.29
130
1184
563
5517
1.28
0.84
5.9
5.5
2.85
2.85
mmol/l
0.01
521
5202
18
121
1.50
0.83
2.6
2.4
—
—
—
0
0
11
65
1.71
0.83
2.5
1.7
32.76
64.04
u/ml
0.21
11
65
6
32
1.88
0.82
4.0
3.8
4519.67
646.16
u/ml
—
6
32
33
251
1.33
0.80
1.6
1.8
—
—
—
0
0
556
5445
1.25
0.80
5.3
4.8
1.61
1.58
mmol/l
0.63
512
5126
411
3932
1.14
0.79
3.5
3.4
—
—
—
0
0
13
82
1.60
0.78
2.1
1.6
—
—
—
0
0
6
34
1.77
0.76
1.2
1.6
1.33
1.13
promille
—
6
25
6
34
1.77
0.76
2.0
2.3
1.80
6.80
nmol/l
—
6
29
78
664
1.20
0.76
2.2
1.6
1.29
1.36
%
0.64
66
591
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
99
1.53
0.76
4.6
3.1
0.23
0.45
iu/ml
—
5
53
11
67
1.65
0.75
1.0
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
529
5162
1.19
0.74
4.4
4.0
1.23
1.23
mmol/l
0.01
477
4823
31
238
1.32
0.72
1.4
1.4
0.27
0.31
mg/l
0.19
14
95
143
1288
1.14
0.70
1.4
1.3
12.90
11.98
u/ml
0.06
57
532
26
195
1.35
0.70
1.2
1.3
—
—
—
0
0
152
1377
1.14
0.69
1.5
1.4
19.75
30.42
iu/ml
1.37
42
429
11
69
1.61
0.68
1.0
1.1
—
—
—
0
0
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
144
1303
1.14
0.66
5.9
3.7
1.02
1.02
kg/l
0.56
85
871
17
236
0.71
0.66
1.3
1.5
1.30
1.10
ratio
—
9
143
17
236
0.71
0.66
1.3
1.5
0.85
0.96
ratio
—
9
143
17
236
0.71
0.66
1.3
1.5
1.18
1.23
ratio
—
9
143
24
180
1.35
0.66
1.7
1.4
349.56
300.76
ug/g
0.56
16
102
34
269
1.28
0.65
3.7
2.9
128.88
130.46
g/l
0.21
34
263
10
62
1.62
0.65
1.0
1.0
—
—
—
0
0
40
490
0.80
0.65
2.9
3.1
—
—
—
0
0
5
29
1.73
0.64
1.2
1.7
115.20
76.77
nmol/24h
—
5
29
30
235
1.29
0.62
4.3
2.9
1.47
1.78
mmol/l
0.20
24
180
35
280
1.27
0.62
1.5
1.3
117.01
227.83
miu/ml
1.33
17
139
17
233
0.72
0.62
1.3
1.5
—
—
—
0
0
9
137
0.65
0.61
1.2
1.5
—
—
—
0
0
21
277
0.75
0.60
1.3
1.5
—
—
—
0
0
45
537
0.83
0.58
1.4
1.3
30.40
27.93
iu/l
0.17
37
466
13
90
1.45
0.55
1.2
1.3
—
—
—
0
0
6
37
1.63
0.55
1.0
1.2
—
—
—
0
0
6
38
1.58
0.54
1.5
1.2
—
—
—
0
0
13
91
1.44
0.53
1.5
1.5
—
—
—
0
0
9
63
1.43
0.52
1.2
1.6
—
—
—
0
0
15
109
1.39
0.51
1.4
1.5
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
110.29
108.59
pmol/l
—
7
46
12
85
1.42
0.47
1.2
1.2
—
—
—
0
0
241
2285
1.09
0.47
4.8
3.5
2.10
0.03
estimate
0.50
49
504
115
1055
1.11
0.44
2.6
2.5
2.43
2.44
mmol/l
0.68
103
959
7
51
1.38
0.44
1.4
1.1
—
—
—
0
0
10
140
0.71
0.43
1.3
1.4
—
—
—
0
0
15
196
0.76
0.43
1.5
1.6
—
—
—
0
0
28
230
1.23
0.43
3.9
2.4
0.63
0.61
%
0.11
28
230
32
267
1.21
0.43
1.6
1.2
0.91
0.88
g/l
0.33
32
267
8
56
1.43
0.42
1.0
1.2
—
—
—
0
0
8
57
1.41
0.42
1.0
1.2
—
—
—
0
0
12
161
0.74
0.41
1.6
1.7
—
—
—
0
0
5
33
1.52
0.41
3.2
1.5
29.97
28.48
ug/l
—
5
33
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
8
59
1.36
0.41
1.0
1.2
—
—
—
0
0
8
59
1.36
0.41
1.0
1.2
—
—
—
0
0
13
97
1.35
0.39
1.2
1.1
—
—
—
0
0
8
61
1.32
0.39
1.0
1.1
—
—
—
0
0
10
71
1.42
0.39
1.0
1.2
—
—
—
0
0
28
233
1.21
0.39
3.9
2.5
1.20
1.19
%
0.01
28
233
46
401
1.16
0.39
8.2
6.5
1.28
1.18
mmol/l
0.20
46
395
553
5461
1.14
0.39
18.9
13.2
20.13
20.09
mg/l
0.01
462
4382
160
1700
0.92
0.38
3.5
3.2
5.00
0.02
estimate
0.49
50
498
12
89
1.36
0.38
1.3
1.8
—
—
—
0
0
21
170
1.24
0.37
1.2
1.2
—
—
—
0
0
65
585
1.12
0.36
1.5
1.8
3.44
3.41
mmol/l
0.09
38
415
12
90
1.34
0.36
1.3
1.1
115.58
119.20
%
0.21
12
82
6
42
1.43
0.35
1.2
1.1
24.77
27.90
nmol/l
—
6
32
6
42
1.43
0.35
1.0
1.5
—
—
—
0
0
40
349
1.16
0.34
1.9
1.4
—
—
—
0
0
21
172
1.23
0.34
1.2
1.2
—
—
—
0
0
6
44
1.37
0.34
1.7
1.3
—
—
—
0
0
83
764
1.10
0.32
1.9
1.9
3.31
3.25
ratio
0.15
53
596
26
224
1.17
0.27
1.2
1.4
110.38
171.99
pmol/l
0.45
26
219
143
1361
1.07
0.25
1.7
1.6
—
—
—
0
0
10
127
0.78
0.25
1.9
1.6
—
—
—
0
0
5
38
1.32
0.23
1.2
1.6
—
—
—
0
0
16
134
1.20
0.23
2.1
1.6
—
—
—
0
0
24
274
0.87
0.23
1.4
1.7
248.21
306.48
mu/l
0.81
19
245
15
125
1.21
0.22
1.9
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.5
—
0.55
—
0
6
0
10
0.00
0.21
0.0
2.1
—
1.21
—
0
10
0
12
0.00
0.21
0.0
1.1
—
15.25
—
0
12
481
4752
1.06
0.21
5.4
5.0
14.54
14.50
pmol/l
0.13
447
4465
53
490
1.09
0.20
3.6
4.2
7.88
8.67
ug/l
0.05
42
396
6
48
1.25
0.20
1.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
5.80
—
0
9
537
5324
1.07
0.20
6.5
6.0
1.74
1.81
mu/l
0.88
497
5037
11
91
1.21
0.17
3.3
2.4
10.75
5.80
umol/l
—
6
65
7
62
1.13
0.17
1.3
1.6
—
—
—
0
0
8
69
1.16
0.16
1.5
1.5
—
—
—
0
0
9
78
1.16
0.15
1.0
1.1
—
—
—
0
0
10
118
0.84
0.14
3.2
2.2
9.10
7.00
pmol/l
—
10
118
31
336
0.92
0.14
2.6
2.1
209.02
5935.63
u/l
—
8
147
8
100
0.80
0.13
1.6
1.5
—
—
—
0
0
11
94
1.17
0.13
2.9
2.1
12.91
13.28
%
0.61
11
94
61
580
1.06
0.13
1.2
1.2
98.89
139.82
u/ml
0.67
22
247
50
475
1.06
0.11
7.9
7.5
0.12
1.04
mmol/l
0.98
39
397
32
302
1.06
0.08
2.4
2.2
5.32
5.56
ug/l
0.05
24
267
10
88
1.14
0.08
1.7
1.3
—
—
—
0
0
10
88
1.14
0.08
1.7
1.3
—
—
—
0
0
16
147
1.09
0.07
1.1
1.2
3.38
3.66
mmol/l
1.29
16
137
22
207
1.07
0.06
2.0
2.0
2.70
4.43
iu/l
—
8
87
11
101
1.09
0.04
1.5
1.2
—
—
—
0
0
71
696
1.02
0.04
2.6
1.8
28.55
29.13
s
0.45
71
673
25
260
0.96
0.03
1.2
1.1
1.62
1.62
g/l
0.02
25
260
18
174
1.04
0.00
1.3
1.2
—
—
—
0
0
13
135
0.96
0.00
1.0
1.1
0.15
0.99
u/ml
—
5
61
10
96
1.04
0.00
1.5
1.5
—
—
—
0
0
17
165
1.03
0.00
1.1
1.1
0.90
1.89
u/ml
—
9
87
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
30.02
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
9.66
—
0
7
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
6.04
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
11.00
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint N14_VAGINAL_LSIL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VAGINAL_LSIL | 1.229 [1.05, 1.44] | 0.012 |
| Birth year | 1.0 [0.99, 1.01] | 0.998 |
During the follow-up period (1.1.1998 — 31.12.2019), 199 out of 2071 females with N14_VAGINAL_LSIL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VAGINAL_LSIL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | No data |
| 5 | 0.814% | No data |
| 10 | 2.011% | No data |
| 15 | 4.023% | No data |
| 20 | 7.318% | No data |
Relationships between endpoints
↥Index endpoint: N14_VAGINAL_LSIL – LSIL lesion of the vagina
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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