LSIL lesion of the vulva

N14_VULVAL_LSIL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N90.0
  • Hospital discharge: ICD-9 0781C
  • Cause of death: ICD-10 N90.0
  • Cause of death: ICD-9 0781C

2 out of 7 registries used, show all original rules.

1196

4. Check minimum number of events

None

1196

5. Include endpoints

None

1196

6. Filter based on genotype QC (FinnGen only)

1085

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6816 6816 -
Only index persons 6423 6423 -
Unadjusted period prevalence (%)
Whole population 0.20 0.20 -
Only index persons 0.24 0.24 -
Median age at first event (years)
Whole population - 32.01 -
Only index persons - 31.60 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1085 1085 -
Unadjusted period prevalence (%) 0.39 0.39 -
Median age at first event (years) 33.80 33.80 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1124
Matched controls
11240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
25.1
307.7
325
179
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
217.0
307.7
182
10
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
307.7
650
*
N90.0
ICD-10 Finland
Mild vulvar dysplasia
+∞
307.7
476
*
ULA02
NOMESCO Finland
Kolposcopy
7.1
224.8
478
1057
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
206.9
157.3
160
9
8326
FHL
Batch conization
60.9
132.3
74
13
N89.0
ICD-10 Finland
Mild vaginal dysplasia
34.4
120.3
77
24
LEB00
NOMESCO Finland
Biopsy of vagina
11.6
118.6
128
123
8411
FHL
Local change laser, coagulation, biopsy or removal
182.7
111.6
115
7
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
4.2
111.1
408
1329
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
16.4
93.9
81
53
A63.0
ICD-10 Finland
Anogenital (venereal) warts
7.4
91.5
142
215
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
35.4
85.3
54
16
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
4.2
75.7
238
674
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
20.3
75.0
58
30
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
3.5
69.7
309
1101
D06BB04
ATC
podophyllotoxin; topical
5.1
62.7
145
320
D06BB10
ATC
imiquimod; topical
5.3
61.7
133
276
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
15.3
53.0
47
32
N87.0
ICD-10 Finland
Mild cervical dysplasia
5.3
52.6
112
229
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
87.4
52.4
58
7
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
4.9
52.1
124
279
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
191.1
36.0
37
*
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
11.2
35.7
38
35
1390
FHL
Colposcopy
175.1
32.9
34
*
LDA10
NOMESCO Finland
Curettage of cervix uteri
3.3
31.0
128
424
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
3.2
27.3
117
395
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
63.7
27.1
31
5
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
42.4
26.9
33
8
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
53.0
26.3
31
6
8113
FHL
Fractional scraping
3.1
25.7
117
409
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
4.5
24.8
61
140
D07AD01
ATC
clobetasol; topical
2.1
23.1
261
1399
LFC00
NOMESCO Finland
Partial excision of vulva
20.0
22.2
33
17
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
6.3
22.0
37
60
J02AC01
ATC
fluconazole; systemic
1.8
21.0
661
4929
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.8
20.1
520
3639
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
2.5
18.9
124
524
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
39.1
18.6
23
6
127
Kela drug reimbursment
Transplant complication
7.0
18.3
28
41
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
18.4
17.8
27
15
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
16.7
351
2283
8339
FHL
Other measure in this category
18.2
16.5
25
14
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
4.1
16.1
44
110
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.4
15.6
39
91
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.9
15.1
45
120
N03AX16
ATC
[U] pregabalin
1.8
14.9
299
1908
A10AB01
ATC
insulin (human); parenteral
3.5
14.7
51
151
A10AA02, ,
ATC
3.6
13.6
45
129
P01AB01
ATC
metronidazole; oral, rectal
1.6
13.4
551
4209
G01AF01
ATC
metronidazole; vaginal
1.9
13.2
192
1105
A10AA01, ,
ATC
3.7
13.1
42
118
N90.4
ICD-10 Finland
Leukoplakia of vulva
10.2
13.0
25
25
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
28.7
13.0
17
6
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
3.0
12.6
55
188
G01AF04
ATC
miconazole; vaginal
2.2
12.5
108
515
G01AA10
ATC
clindamycin; vaginal
1.7
12.1
276
1811
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.3
12.0
24
46
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
14.8
11.8
19
13
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.8
11.7
191
1137
8112
FHL
Scraping the cervix
30.4
11.7
15
5
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.9
11.5
53
187
A11CC03
ATC
alfacalcidol; systemic
4.1
11.2
30
74
N02AX02
ATC
tramadol; systemic, rectal
1.5
11.1
469
3559
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
43.8
10.9
13
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
2.9
10.9
50
176
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
15.7
10.8
17
11
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
18.0
10.7
16
9
L29.2
ICD-10 Finland
Pruritus vulvae
3.2
10.6
41
130
8511
FHL
Cervical dilation and drainage with suction
2.3
10.6
79
353
J01FF01
ATC
clindamycin; systemic
1.6
10.5
310
2160
A10AC01
ATC
insulin (human); parenteral
2.3
10.4
81
370
A10AE04
ATC
insulin glargine; parenteral
2.2
10.3
92
444
L04AA06
ATC
mycophenolic acid; systemic
4.1
10.3
28
70
UJF32
NOMESCO Finland
Coloscopy
1.6
10.2
276
1881
A02BC02
ATC
pantoprazole; systemic
1.6
10.0
791
6795
Z01.2
ICD-10 Finland
Dental examination
1.5
10.0
574
4612
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
10.0
504
3943
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
9.9
51
191
L04AD02
ATC
tacrolimus; systemic
7.5
9.7
22
30
E0000UV, ,
ATC
1.5
9.6
493
3860
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
9.6
455
3506
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
9.6
340
2464
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
2.6
9.6
55
218
TK800
NOMESCO Finland
Hemodialysis
4.8
9.6
21
44
7020X
ICD-9 Finland
Other dermatoses, Actinic keratosis[DERMATOSES PRAECANCEROSAE ALIAE]
100.9
9.4
10
*
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
9.4
300
2121
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.7
9.3
48
180
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
9.3
92
462
ZXA05
NOMESCO Finland
Left side
1.6
9.2
250
1701
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.5
9.0
30
87
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
9.0
132
760
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
24.2
8.9
12
5
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
24.2
8.9
12
5
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
8.9
63
276
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
12.6
8.9
15
12
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.9
388
2930
C03CA01
ATC
furosemide; systemic
1.6
8.8
233
1576
Z25.1
ICD-10 Finland
Need for immunization against influenza
2.3
8.8
63
278
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
50.4
8.7
10
*
Z2221
NOMESCO Finland
Medical doctor
1.5
8.7
322
2348
A12AA04
ATC
calcium carbonate; oral
4.9
8.4
18
37
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
3.8
8.4
25
67
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
8.4
152
931
A10AB04
ATC
insulin lispro; parenteral
2.8
8.3
42
156
H04AA01
ATC
glucagon; nasal, parenteral
3.4
8.2
29
87
N76.6
ICD-10 Finland
Ulceration of vulva
4.3
8.2
21
50
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.3
8.2
21
50
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
8.2
112
630
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
8.1
82
415
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.1
360
2717
H3603, E103,
ICD-10 Finland
6.9
8.1
19
28
N01BB02
ATC
lidocaine; parenteral
4.2
8.0
21
51
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
8.0
309
2266
6230A
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE LEVIS]
45.3
7.7
9
*
J01MA12
ATC
levofloxacin; systemic
1.6
7.7
180
1177
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
8.1
7.6
16
20
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.6
459
3664
R4110
NOMESCO Finland
Physiotherapy
1.5
7.5
300
2210
N06AX12
ATC
bupropion; oral
1.9
7.5
97
536
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
3.1
7.5
30
98
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.9
7.5
21
54
Z94.0
ICD-10 Finland
Kidney transplant status
6.5
7.4
18
28
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
7.4
195
1314
TLC02
NOMESCO Finland
Simple extraction of IUD
2.0
7.4
84
445
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.3
7.3
56
254
J01DA01
ATC
[U] cefalexin
1.4
7.3
722
6263
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.3
270
1959
ZXD05
NOMESCO Finland
Urgent procedure
1.5
7.3
324
2438
H02AB06
ATC
prednisolone; systemic
1.4
7.2
522
4288
A46
ICD-10 Finland
Erysipelas
1.7
7.2
124
748
L04AA01
ATC
[U] ciclosporin
4.0
7.2
20
51
K29.4
ICD-10 Finland
Chronic atrophic gastritis
3.6
7.2
23
65
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.8
7.1
14
16
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.0
247
1770
G01AF02
ATC
clotrimazole; vaginal
2.0
7.0
73
374
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.0
233
1651
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
2.9
7.0
32
113
T89
ICPC
Diabetes insulin dependent
2.4
6.9
47
203
A10AB05
ATC
insulin aspart; parenteral
2.0
6.9
70
356
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
8.3
6.8
14
17
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
2.5
6.8
42
173
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.8
130
806
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.8
677
5844
Z3231
NOMESCO Finland
Registered nurse
1.5
6.8
274
2019
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.8
195
1338
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.3
6.8
48
211
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
5.7
6.8
18
32
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
6.7
408
3239
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.7
445
3590
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
6.5
6.6
16
25
G01AF05
ATC
econazole; vaginal
1.6
6.5
143
919
A02BC05
ATC
esomeprazole; systemic
1.4
6.5
465
3788
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.7
6.5
131
824
J01EA01
ATC
trimethoprim; systemic
1.4
6.5
336
2590
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
6.4
117
716
J01DB01
ATC
cefalexin; oral
1.5
6.4
925
8487
N02AA05
ATC
oxycodone; systemic
1.6
6.2
154
1019
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.2
185
1278
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.2
128
811
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
6.2
66
342
M05BA07
ATC
risedronic acid; oral
2.5
6.2
37
151
D07AC01
ATC
betamethasone; topical
1.4
6.2
397
3174
L04AX01
ATC
azathioprine; systemic
2.2
6.1
49
227
S20.2
ICD-10 Finland
Contusion of thorax
2.1
6.1
53
254
R2110
NOMESCO Finland
Giving the first information
1.8
6.1
96
564
LCA06
NOMESCO Finland
Biopsy of endometrium
1.5
6.1
206
1463
ZXA00
NOMESCO Finland
Right side
1.4
6.1
258
1916
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.0
380
3023
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
3.2
6.0
23
73
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
6.0
72
388

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
179
293
7.08
107.85
3.2
1.9
—
—
—
0
0
652
4662
1.95
25.72
3.4
2.1
—
—
—
0
0
259
1429
2.06
20.98
3.6
2.8
5.06
4.76
e6/l
0.15
143
617
477
3425
1.68
15.61
7.8
5.9
—
—
—
0
0
428
3027
1.67
14.58
4.7
3.0
48.64
80.79
e6/l
0.56
331
2266
255
1610
1.76
12.95
3.4
2.6
1.21
1.14
e6/l
0.11
137
803
192
1139
1.83
11.95
9.5
4.6
1.07
1.04
mmol/l
0.91
181
1035
435
3208
1.58
11.87
2.8
2.2
—
—
—
0
0
369
2621
1.61
11.79
4.6
2.8
0.25
0.41
e6/l
2.06
276
1869
477
3618
1.55
11.37
5.9
3.6
89.50
84.33
e6/l
0.09
351
2448
560
4420
1.53
11.01
6.5
4.3
35.93
36.52
g/l
1.85
547
4174
182
1098
1.78
10.65
2.3
1.6
—
—
—
0
0
557
4431
1.51
10.30
8.6
5.5
1.22
1.22
mmol/l
0.85
529
4126
123
666
1.95
10.09
11.6
6.5
8.57
8.21
mmol/l
0.28
116
644
236
1565
1.64
9.71
1.2
1.2
—
—
—
0
0
239
1597
1.63
9.52
4.3
3.0
0.81
0.82
mmol/l
0.24
234
1507
651
5409
1.48
9.34
8.5
6.0
0.55
0.53
e9/l
1.04
584
4716
421
3214
1.50
9.20
3.7
2.9
—
—
—
0
0
661
5521
1.48
9.15
8.6
6.0
1.97
1.95
e9/l
0.15
614
4928
650
5421
1.47
8.99
8.5
6.0
0.04
0.04
e9/l
0.02
585
4720
116
643
1.90
8.87
1.3
1.2
—
—
—
0
0
597
4919
1.46
8.66
8.6
6.1
8.48
8.38
%
0.41
561
4641
602
4971
1.45
8.61
8.4
6.0
56.34
56.58
%
0.21
573
4770
604
4993
1.45
8.57
9.3
6.2
1.22
1.22
mmol/l
1.25
557
4338
150
909
1.75
8.57
1.5
1.4
—
—
—
0
0
329
2418
1.51
8.51
2.6
2.2
—
—
—
0
0
665
5605
1.46
8.47
8.8
6.3
0.19
0.18
e9/l
0.70
617
4962
594
4905
1.45
8.42
8.6
6.1
0.69
0.70
%
0.30
560
4605
764
6619
1.48
8.41
6.0
4.5
2313.71
3598.72
e6/l
—
7
78
594
4912
1.44
8.31
8.6
6.1
2.85
2.77
%
0.40
558
4631
249
1731
1.56
8.29
4.6
2.6
467.85
491.41
mosm/kgh2o
1.03
227
1521
606
5053
1.43
7.96
8.6
6.1
29.05
29.10
%
0.04
579
4818
415
3237
1.45
7.81
9.5
5.9
—
—
—
0
0
705
6067
1.43
7.63
13.2
9.3
3.87
3.91
e9/l
0.19
631
5331
212
1446
1.57
7.62
1.3
1.2
—
—
—
0
0
415
3250
1.44
7.59
2.8
2.4
52.89
59.73
u/l
2.44
397
3017
342
2586
1.46
7.53
5.5
3.4
96.77
97.43
%
0.21
332
2520
228
1594
1.54
7.32
3.5
2.3
13.34
13.59
umol/l
0.21
220
1495
15
19
7.99
7.11
1.5
1.3
7.44
8.29
mmol/l
0.21
15
19
281
2074
1.47
6.91
3.9
2.5
7.29
7.87
e6/l
0.26
256
1897
20
53
3.82
6.82
3.3
3.1
80.11
9.53
mg/l
—
10
31
176
1178
1.59
6.82
1.6
1.5
—
—
—
0
0
630
5376
1.39
6.76
7.5
5.9
9.44
9.98
umol/l
0.71
620
5139
63
311
2.09
6.71
2.8
2.1
1.49
1.50
g/l
0.03
55
277
300
2255
1.45
6.69
5.0
3.8
—
—
—
0
0
208
1460
1.52
6.50
3.7
2.3
2.36
2.42
g/l
1.00
195
1367
133
844
1.65
6.39
2.8
3.7
4.44
4.52
pmol/l
0.23
116
757
113
690
1.71
6.27
10.2
7.6
—
—
—
0
0
190
1319
1.53
6.24
3.9
2.3
21.74
22.59
%
0.48
182
1235
521
4352
1.37
6.16
2.3
2.0
100.40
99.61
pmol/l
0.13
270
2205
64
330
2.00
6.09
1.4
1.4
304.59
305.72
ug/g
0.01
41
189
218
1575
1.48
5.89
2.1
2.3
167.34
100.77
ug/g
1.07
177
1252
640
5545
1.36
5.87
4.9
3.9
0.00
0.01
estimate
1.63
103
1086
148
993
1.56
5.65
2.5
2.0
0.00
0.04
estimate
1.05
24
207
310
2407
1.40
5.63
3.2
2.8
890.96
774.37
ng/l
0.32
273
2039
627
5442
1.34
5.54
4.9
3.8
0.00
0.00
estimate
0.80
105
1104
345
2736
1.38
5.50
1.8
1.6
21.48
21.56
nmol/l
0.03
312
2370
312
2435
1.39
5.48
1.5
1.5
2.14
2.18
g/l
0.18
194
1555
15
29
5.23
5.40
2.7
2.5
0.58
0.63
mmol/l
1.42
15
29
863
7901
1.40
5.23
10.5
7.7
75.48
76.70
u/l
0.57
820
7534
90
544
1.71
5.21
3.2
2.0
10.48
7.34
iu/ml
0.45
27
137
83
491
1.75
5.18
1.2
1.2
—
—
—
0
0
120
783
1.60
5.16
1.4
1.3
—
—
—
0
0
630
5506
1.33
5.14
4.9
3.8
0.00
5.59
estimate
1.33
109
1140
181
1295
1.47
5.10
2.7
1.9
—
—
—
0
0
40
185
2.21
5.08
1.6
1.3
—
—
—
0
0
477
4014
1.33
5.04
12.7
10.6
1.15
1.13
inr
0.25
380
3310
146
1003
1.52
5.01
2.3
2.3
32.53
39.13
u/l
1.12
119
828
326
2596
1.36
4.98
2.3
2.2
2.99
2.77
mg/l
0.65
298
2255
124
823
1.57
4.97
3.5
3.2
9.88
10.42
g/l
0.77
116
773
270
2088
1.39
4.95
2.8
2.5
2.44
2.44
mmol/l
0.12
231
1895
443
3708
1.32
4.80
4.1
2.9
33.18
29.22
u/l
0.58
423
3527
129
872
1.54
4.77
3.3
2.7
1.88
1.84
%
0.16
119
785
59
323
1.87
4.76
1.2
1.2
—
—
—
0
0
309
2459
1.35
4.70
4.8
3.8
—
0.18
—
0
22
61
339
1.85
4.70
2.6
3.3
—
—
—
0
0
230
1746
1.40
4.68
4.0
3.6
97.95
328.77
ng/l
2.42
141
1144
124
835
1.55
4.67
5.6
3.1
7.38
7.38
ph
0.50
73
461
81
491
1.70
4.66
6.1
3.1
24.23
24.46
mmol/l
0.23
81
483
167
1197
1.46
4.66
2.8
2.3
5.32
5.74
umol/l
0.24
145
1042
127
861
1.54
4.64
2.7
2.4
5.98
6.09
ph
0.88
86
532
382
3144
1.33
4.62
4.7
3.2
6.61
6.91
mmol/l
0.82
319
2696
91
573
1.64
4.54
2.3
2.9
192.97
150.87
ng/l
0.36
80
519
36
168
2.18
4.50
1.6
1.3
151.32
161.51
au/ml
0.24
15
48
197
1467
1.42
4.47
1.8
1.7
1246.39
1184.43
nmol/l
0.41
168
1123
133
920
1.51
4.42
2.8
2.1
0.21
0.22
g/l
0.53
128
875
637
5642
1.30
4.40
6.3
4.3
6.64
6.44
mmol/l
1.17
610
5328
357
2927
1.32
4.39
4.7
3.3
47.56
30.91
mg/l
0.58
221
1682
445
3761
1.30
4.39
4.1
3.5
2.36
2.36
mmol/l
0.18
405
3479
79
486
1.67
4.32
2.9
3.2
7.41
7.42
ph
0.54
64
413
119
810
1.52
4.27
5.7
3.0
1.86
2.07
mmol/l
0.21
104
707
374
3098
1.31
4.25
3.6
2.9
0.29
0.04
—
7
51
590
5199
1.28
4.13
3.2
2.5
78.30
78.46
nmol/l
0.05
541
4816
38
188
2.06
4.12
1.4
1.2
337.85
274.76
u/ml
0.64
30
119
118
810
1.51
4.08
5.6
3.2
102.90
74.90
ng/l
1.68
106
719
97
640
1.56
4.01
2.8
2.8
69.85
74.61
e9/l
0.51
66
458
59
342
1.77
4.00
1.2
1.2
—
—
—
0
0
173
1285
1.41
3.97
1.6
1.4
—
—
—
0
0
357
2962
1.30
3.96
5.6
3.9
9.13
6.72
mg/mmol
0.39
219
1670
48
263
1.86
3.91
6.3
2.9
1.85
2.15
index
0.12
27
136
175
1307
1.40
3.89
2.9
1.9
29.19
29.20
s
0.01
170
1269
533
4661
1.27
3.88
13.3
10.1
0.00
0.00
e9/l
0.08
449
3805
58
338
1.75
3.87
1.2
1.2
—
—
—
0
0
10
19
5.30
3.83
6.5
4.8
—
—
—
0
0
538
4724
1.27
3.74
3.1
2.6
—
—
estimate
—
0
0
106
727
1.51
3.69
3.2
2.4
0.29
0.55
e6/l
0.68
98
683
96
645
1.53
3.68
1.9
1.9
1.52
1.36
g/l
0.25
91
603
1044
10037
1.56
3.68
20.3
13.7
20.72
19.78
mg/l
0.42
889
8142
20
80
2.53
3.56
6.4
2.6
12.50
12.83
index
0.08
12
48
128
920
1.44
3.53
7.7
7.5
1.28
1.11
mmol/l
0.22
111
758
502
4401
1.25
3.44
4.2
3.4
6.26
6.22
ph
0.28
276
2566
236
1888
1.32
3.36
1.9
1.8
—
—
—
0
0
74
480
1.58
3.33
2.6
2.0
0.00
0.01
estimate
0.80
25
162
9
19
4.77
3.24
1.0
1.0
—
—
—
0
0
101
706
1.47
3.23
4.7
2.5
4.64
4.54
kpa
0.19
94
684
344
2907
1.26
3.18
1.4
1.3
2.02
1.62
u/ml
0.14
99
807
1023
9836
1.45
3.14
6.9
6.1
1.78
1.81
mu/l
0.47
969
9353
50
298
1.71
3.14
10.6
7.8
—
—
—
0
0
10
25
4.03
3.09
2.3
1.6
—
—
—
0
0
91
630
1.48
3.06
1.1
1.1
—
154.33
—
0
15
126
928
1.40
3.05
8.2
7.5
7.43
7.42
ph
0.83
64
527
48
287
1.70
2.99
2.6
3.1
1522.86
326.76
mg/l
0.49
21
91
160
1230
1.35
2.99
1.4
1.3
—
—
—
0
0
306
2568
1.26
2.98
2.0
1.7
0.95
0.87
mg/l
0.31
236
1975
223
1801
1.30
2.95
1.5
1.4
523.57
560.30
titre
0.17
56
399
790
7355
1.25
2.92
3.6
3.2
41.43
38.77
u/l
0.49
765
7019
374
3225
1.24
2.85
3.6
3.1
—
0.78
—
0
9
144
1098
1.36
2.84
2.0
2.0
384.83
375.64
nmol/l
0.22
136
1032
199
1592
1.30
2.82
1.7
1.6
—
—
—
0
0
73
492
1.52
2.81
1.9
1.9
1941.61
4769.75
u/l
0.66
26
184
301
2539
1.25
2.78
3.0
2.3
313.55
306.61
umol/l
0.59
273
2282
927
8818
1.29
2.72
5.6
5.0
14.72
14.51
pmol/l
1.84
876
8333
1087
10621
1.71
2.70
15.1
11.5
23.73
23.97
u/l
0.26
1075
10408
354
3058
1.23
2.61
6.9
3.7
7.40
7.40
ph
0.25
254
2175
8
20
4.02
2.57
1.1
1.2
—
—
—
0
0
11
36
3.08
2.57
1.9
1.4
—
—
—
0
0
5
7
7.17
2.55
6.0
7.6
4.02
5.43
mmol/l
—
5
7
1001
9645
1.35
2.51
4.6
4.1
1.30
1.24
mmol/l
1.81
950
9067
7
16
4.40
2.47
1.3
4.4
—
—
—
0
0
610
5581
1.20
2.46
3.8
3.1
102.15
81.91
ug/l
1.76
584
5302
13
51
2.57
2.45
1.4
1.3
27514.50
70856.33
e6/l
—
8
27
18
83
2.19
2.42
1.4
1.4
—
—
—
0
0
40
245
1.66
2.34
1.3
1.3
—
7.96
—
0
7
398
3513
1.21
2.32
3.9
3.2
20.57
57.96
ng/l
0.99
240
2079
408
4561
0.83
2.24
3.1
3.0
—
—
—
0
0
12
48
2.52
2.19
8.2
2.7
0.67
0.81
index
0.30
12
48
344
3010
1.21
2.18
2.3
2.1
130.06
155.66
u/l
0.49
333
2868
81
1093
0.72
2.15
1.7
1.8
3.60
3.51
mmol/l
0.42
51
758
57
389
1.49
2.13
3.9
1.9
1.13
1.21
g/l
1.38
57
368
49
324
1.54
2.12
1.5
1.4
35.26
29.94
u/l
0.51
43
268
124
973
1.31
2.05
3.8
4.0
3.54
14.13
ug/l
1.50
99
765
127
1000
1.30
2.05
1.2
1.2
—
—
—
0
0
502
4579
1.17
1.93
2.0
1.9
1.37
1.36
mmol/l
0.12
439
3991
26
150
1.75
1.92
1.1
1.3
0.17
0.30
nmol/l
0.45
18
106
74
543
1.39
1.91
1.4
1.3
0.27
0.99
u/ml
—
10
44
981
9490
1.27
1.89
7.2
5.6
39.32
38.28
mmol/mol
2.79
940
9021
12
52
2.32
1.88
1.7
1.5
—
—
—
0
0
16
79
2.04
1.86
1.2
1.4
17.71
10.20
umol/l
1.50
16
73
46
310
1.50
1.85
1.1
1.2
—
—
—
0
0
22
122
1.82
1.85
1.7
1.4
—
—
—
0
0
5
12
4.18
1.82
1.0
1.0
5.68
5.43
nmol/l
—
5
12
12
53
2.28
1.81
1.7
1.3
—
—
—
0
0
113
1415
0.78
1.80
1.9
2.0
3.27
3.27
ratio
0.00
82
1067
1106
10916
1.82
1.79
29.8
21.3
6.64
6.58
e9/l
0.36
1091
10729
1106
10916
1.82
1.79
29.7
21.2
4.40
4.44
e12/l
1.65
1090
10733
461
4198
1.17
1.77
4.6
3.7
7.69
0.06
estimate
0.61
78
896
1039
10138
1.33
1.76
21.8
14.7
139.67
139.76
mmol/l
0.61
1029
9966
274
2391
1.19
1.76
4.8
3.9
1.02
1.65
kg/l
0.50
184
1600
80
606
1.34
1.72
2.2
2.2
4.12
5.78
ug/l
0.76
74
535
80
607
1.34
1.70
2.1
2.3
—
—
—
0
0
330
2934
1.18
1.70
5.1
4.0
0.00
0.00
estimate
0.80
100
1066
55
394
1.42
1.65
3.1
1.7
20.15
20.29
s
0.11
48
337
11
49
2.26
1.64
3.0
2.7
31.76
187.93
ug/l
0.45
11
42
1105
10913
1.74
1.63
29.9
21.2
267.12
267.37
e9/l
0.04
1094
10759
35
230
1.54
1.61
1.3
1.1
—
—
—
0
0
10
43
2.34
1.59
2.8
3.2
—
—
—
0
0
1082
10642
1.45
1.57
24.5
17.0
70.53
67.93
umol/l
1.84
1072
10537
1039
10158
1.30
1.56
22.5
14.9
3.94
3.93
mmol/l
1.11
1029
9961
6
22
2.74
1.43
1.0
1.0
—
—
—
0
0
7
29
2.42
1.39
1.0
1.0
6.74
7.27
u/ml
—
7
29
50
365
1.39
1.39
1.8
1.7
—
—
—
0
0
13
67
1.95
1.38
1.1
1.2
—
—
—
0
0
1060
10410
1.32
1.37
16.3
12.1
—
—
—
0
0
6
23
2.62
1.37
2.0
3.6
53.58
49.91
%
—
6
23
1037
10158
1.27
1.35
5.6
4.9
4.86
4.89
mmol/l
0.54
999
9670
0
40
0.00
1.32
0.0
1.8
—
—
—
0
0
90
722
1.27
1.32
2.3
2.7
65.08
67.66
g/l
1.79
81
676
112
923
1.24
1.31
3.5
3.7
7.35
7.36
ph
0.20
90
663
57
431
1.34
1.29
1.6
1.6
301.36
319.70
mu/l
0.24
50
387
14
77
1.83
1.25
1.2
1.9
—
—
—
0
0
26
171
1.53
1.24
1.0
1.0
—
—
—
0
0
26
171
1.53
1.24
2.9
2.4
169.34
117.32
ug/min
0.17
15
109
39
535
0.72
1.23
1.1
1.1
1.60
1.63
g/l
0.41
39
535
21
132
1.60
1.21
1.1
1.5
18.31
22.26
ng/l
0.99
21
132
18
109
1.66
1.19
1.4
1.8
56.69
50.40
%
0.24
13
65
51
385
1.34
1.18
1.5
1.4
0.25
0.30
mg/l
0.55
25
158
289
2612
1.14
1.17
1.4
1.4
23.70
26.80
iu/ml
0.27
81
819
14
79
1.78
1.17
1.0
1.1
—
—
—
0
0
998
9759
1.20
1.17
5.5
4.8
5.86
5.75
mmol/l
1.96
945
9170
10
50
2.01
1.16
1.5
1.2
—
—
—
0
0
26
174
1.51
1.16
1.1
1.3
—
0.46
nmol/l
—
0
7
5
20
2.51
1.15
2.8
2.0
23.50
22.48
umol/l
—
5
20
0
36
0.00
1.14
0.0
1.0
—
—
—
0
0
0
36
0.00
1.14
0.0
1.0
—
—
—
0
0
0
36
0.00
1.14
0.0
1.0
—
—
—
0
0
52
397
1.32
1.13
1.3
1.3
9.41
12.11
u/ml
—
7
70
8
40
2.01
1.12
5.1
1.6
—
—
—
0
0
10
51
1.97
1.11
2.8
2.9
—
—
—
0
0
25
168
1.50
1.10
1.1
1.3
0.51
11.12
nmol/l
0.50
25
162
27
185
1.47
1.09
4.7
4.1
—
—
—
0
0
34
244
1.41
1.08
1.1
1.2
19.81
17.69
u/l
0.24
28
196
15
89
1.69
1.08
2.3
2.2
1.29
0.87
g/24h
—
9
53
16
97
1.66
1.07
1.4
1.2
—
63.93
—
0
8
19
121
1.58
1.06
1.5
1.4
—
—
—
0
0
30
212
1.43
1.04
2.5
3.9
1.25
2.00
ratio
1.33
17
127
50
385
1.31
1.04
2.2
2.1
2.51
17.72
iu/l
0.59
24
173
7
34
2.07
1.03
1.4
1.2
25.86
28.18
s
—
7
34
1042
10249
1.23
1.02
6.3
5.5
2.84
2.87
mmol/l
0.60
995
9727
1030
10120
1.21
1.02
5.5
4.8
1.55
1.58
mmol/l
1.20
983
9589
101
849
1.21
1.01
1.3
1.2
—
—
—
0
0
57
449
1.28
1.01
2.2
1.9
—
—
—
0
0
102
1204
0.83
1.01
1.3
1.4
—
—
—
0
0
7
35
2.01
1.00
1.7
2.3
7.43
6.80
%
—
7
35
11
61
1.81
0.98
1.3
1.4
29.89
30.87
umol/l
0.20
11
55
119
1021
1.19
0.97
1.2
1.2
169.91
154.55
u/ml
0.16
41
426
30
216
1.40
0.96
2.1
2.3
—
—
—
0
0
38
285
1.34
0.96
1.0
1.1
—
—
—
0
0
7
37
1.90
0.94
1.7
2.2
29.71
29.76
%
—
7
37
58
465
1.26
0.91
1.3
1.3
171.64
236.36
miu/ml
0.82
27
237
23
159
1.46
0.91
1.0
1.1
—
—
—
0
0
21
143
1.48
0.90
1.7
1.5
307.00
367.21
mu/l
0.71
16
116
77
639
1.22
0.90
1.1
1.1
—
—
—
0
0
6
29
2.07
0.89
1.0
1.3
188.50
367.42
pmol/l
—
6
24
64
522
1.24
0.88
2.4
2.3
—
—
—
0
0
24
169
1.43
0.88
7.2
2.8
—
—
—
0
0
8
43
1.87
0.87
1.3
1.1
—
—
—
0
0
27
196
1.39
0.84
3.3
3.5
4.08
4.15
e9/l
0.07
27
196
6
31
1.94
0.84
1.2
1.3
19.83
17.18
umol/l
—
6
24
35
266
1.33
0.83
2.3
1.4
8.08
15.49
e6/l
0.62
26
193
23
163
1.42
0.82
1.7
1.8
—
—
—
0
0
12
74
1.63
0.78
1.0
1.3
—
—
—
0
0
23
165
1.40
0.78
1.1
1.1
—
—
—
0
0
76
895
0.84
0.77
1.6
1.8
—
—
—
0
0
67
798
0.83
0.76
6.4
3.3
1.23
1.24
mmol/l
0.49
61
693
44
548
0.79
0.76
1.3
1.2
0.92
0.90
g/l
0.30
44
548
10
59
1.70
0.76
1.0
1.5
164.20
158.63
mmol/24h
—
10
59
15
99
1.52
0.76
2.3
2.4
—
—
—
0
0
35
271
1.30
0.75
2.3
1.5
428.70
1408.91
e6/l
0.46
30
208
5
24
2.09
0.74
1.0
1.3
—
39.86
—
0
14
9
54
1.67
0.74
1.2
1.7
54.11
70.26
nmol/24h
—
9
54
11
172
0.64
0.74
2.1
2.4
—
—
—
0
0
29
219
1.33
0.74
2.0
1.8
121.04
130.64
g/l
1.50
23
172
329
3078
1.10
0.72
3.9
3.2
3.40
0.03
estimate
0.55
81
888
21
151
1.40
0.71
1.1
1.3
—
—
nmol/l
—
0
0
16
109
1.47
0.71
2.1
1.7
3.91
39.79
u/ml
0.53
16
109
101
882
1.16
0.70
5.3
4.5
0.07
0.13
%
0.43
27
208
23
169
1.37
0.70
1.5
1.3
—
—
—
0
0
20
144
1.40
0.68
1.1
1.1
—
—
—
0
0
11
70
1.58
0.65
2.2
2.7
—
—
—
0
0
31
242
1.29
0.65
3.2
3.4
58.62
58.90
%
0.05
31
242
104
921
1.14
0.62
5.1
4.4
0.62
1.07
%
1.24
30
247
10
63
1.59
0.62
1.2
1.9
32.95
25.82
ug/l
—
10
63
34
421
0.80
0.60
1.4
1.6
1414.05
1006.09
mu/l
1.08
26
336
260
2431
1.09
0.59
1.4
1.3
4.82
9.93
u/ml
1.28
102
994
20
149
1.35
0.58
1.1
1.2
—
—
—
0
0
21
158
1.34
0.57
12.0
3.0
3.01
2.69
mmol/l
0.14
14
107
22
167
1.32
0.57
5.0
1.7
—
—
—
0
0
6
37
1.62
0.55
1.0
1.2
—
6.67
%
—
0
6
13
90
1.45
0.55
1.5
1.4
1.11
1.64
nmol/l
0.94
13
80
11
159
0.69
0.54
1.0
1.1
—
—
—
0
0
100
897
1.13
0.51
5.5
4.7
0.04
0.54
%
0.60
23
186
13
92
1.42
0.50
1.2
1.1
—
—
—
0
0
10
67
1.50
0.49
1.3
1.1
6.29
6.52
mmol/l
—
10
62
130
1189
1.11
0.48
1.3
1.4
29.30
32.93
iu/l
0.54
107
1041
44
373
1.19
0.48
3.2
1.5
—
—
—
0
0
22
173
1.28
0.46
1.1
1.3
—
70.47
—
0
12
41
347
1.19
0.46
3.0
1.5
—
—
—
0
0
44
377
1.17
0.44
3.1
1.5
—
—
—
0
0
44
377
1.17
0.44
3.1
1.5
—
—
—
0
0
38
322
1.19
0.43
3.1
3.1
49.63
656.05
u/ml
0.81
32
280
33
276
1.20
0.42
1.3
1.2
—
—
—
0
0
35
295
1.19
0.42
3.6
1.5
—
—
—
0
0
44
379
1.17
0.41
3.1
1.5
—
—
—
0
0
13
96
1.36
0.41
2.4
2.6
—
—
—
0
0
98
892
1.11
0.41
1.4
1.3
172.59
162.24
u/ml
0.06
93
834
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
12
88
1.37
0.40
1.9
1.3
—
—
—
0
0
8
61
1.31
0.39
6.0
3.2
1594.38
975.70
u/ml
—
8
61
5
35
1.43
0.39
5.2
2.0
0.00
0.00
estimate
—
5
35
16
204
0.78
0.39
1.3
1.5
—
—
—
0
0
16
203
0.79
0.38
1.3
1.5
1.39
1.31
mm
—
10
137
96
879
1.10
0.37
2.4
2.5
25.25
22.80
au/ml
0.09
11
105
218
2069
1.07
0.36
1.7
1.7
490.30
37697064.71
pmol/l
2.46
193
1780
17
212
0.80
0.36
1.3
1.5
—
—
—
0
0
54
480
1.13
0.35
1.6
1.7
13.64
13.02
u/ml
—
8
122
6
43
1.40
0.35
1.8
2.1
7.23
8.96
mg/l
—
6
35
861
8725
0.94
0.34
25.6
17.4
330.61
330.88
g/l
0.43
856
8682
12
91
1.32
0.34
4.8
2.0
32.28
8.94
ug/l
0.42
12
78
13
100
1.30
0.33
1.2
1.1
—
—
—
0
0
16
128
1.25
0.32
2.3
2.1
—
—
—
0
0
22
183
1.21
0.32
1.7
1.4
—
—
—
0
0
17
208
0.81
0.31
1.1
1.0
0.95
3.53
u/ml
—
5
94
17
138
1.24
0.30
3.5
3.0
1.97
1.54
%
0.16
17
128
17
139
1.23
0.29
1.7
1.5
—
—
—
0
0
13
103
1.27
0.28
1.6
2.0
34.31
31.50
pg
1.64
13
103
76
822
0.92
0.27
5.4
3.8
—
—
—
0
0
28
243
1.16
0.27
2.4
1.4
—
—
—
0
0
12
95
1.27
0.26
1.1
1.1
—
—
—
0
0
94
878
1.08
0.26
5.1
4.3
0.38
0.78
%
0.60
24
231
254
2633
0.95
0.25
5.9
4.4
—
—
—
0
0
9
75
1.20
0.25
3.4
3.7
—
—
—
0
0
15
124
1.21
0.24
3.3
5.7
9.74
43.93
u/ml
—
5
41
128
1215
1.06
0.23
1.7
1.7
—
—
—
0
0
103
971
1.07
0.23
1.6
1.7
—
—
—
0
0
146
1394
1.05
0.22
1.4
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
35.70
—
0
10
23
201
1.15
0.21
1.1
1.2
—
—
—
0
0
148
1416
1.05
0.21
2.8
3.0
4.37
4.27
e9/l
0.11
137
1264
0
12
0.00
0.21
0.0
1.0
—
0.00
—
0
6
0
13
0.00
0.21
0.0
2.2
—
2.85
—
0
13
25
282
0.88
0.20
1.1
1.1
2.33
2.17
u/ml
—
6
153
0
14
0.00
0.20
0.0
3.6
—
—
—
0
0
0
14
0.00
0.20
0.0
3.5
—
—
—
0
0
0
14
0.00
0.20
0.0
7.4
—
4.98
—
0
14
6
48
1.25
0.20
1.3
1.3
—
—
—
0
0
11
90
1.22
0.19
2.4
2.2
1.21
1.20
mmol/l
0.18
11
90
718
7102
1.03
0.17
4.2
3.5
—
0.27
—
0
11
285
2784
1.03
0.16
1.4
1.5
—
—
—
0
0
8
71
1.13
0.16
15.2
14.2
0.75
0.67
mmol/l
—
8
62
11
92
1.20
0.16
2.4
2.2
103.45
105.79
mmol/l
1.16
11
92
11
92
1.20
0.16
2.4
2.2
4.22
3.96
mmol/l
1.01
11
92
11
92
1.20
0.16
1.3
1.1
—
—
—
0
0
21
187
1.13
0.16
1.2
1.2
2.09
3.85
u/ml
0.60
11
66
12
103
1.17
0.13
1.0
1.2
34.03
30.78
mg/l
—
7
84
13
149
0.87
0.13
1.1
1.1
—
—
—
0
0
15
132
1.14
0.13
3.0
1.6
—
—
—
0
0
13
113
1.15
0.13
1.5
2.0
1.08
0.88
%
—
8
69
23
209
1.10
0.13
2.8
2.5
1.61
1.50
mmol/l
0.21
23
204
12
104
1.16
0.12
1.4
1.1
102.58
116.88
pmol/l
0.57
12
104
22
240
0.92
0.11
1.1
1.0
9.71
3.30
u/ml
—
5
120
14
156
0.90
0.10
1.0
1.1
96.60
3719.03
iu/ml
—
5
34
5
45
1.11
0.10
2.0
1.4
—
—
—
0
0
24
223
1.08
0.09
1.2
1.2
—
—
—
0
0
5
64
0.78
0.08
1.4
1.6
58.80
88.53
ng/l
—
5
64
9
84
1.07
0.07
1.0
1.1
—
—
—
0
0
9
103
0.87
0.06
4.1
2.6
—
—
—
0
0
10
92
1.09
0.03
1.8
2.0
89.46
90.27
%
—
10
92
12
112
1.07
0.03
1.3
1.1
—
—
—
0
0
11
118
0.93
0.02
2.4
1.4
—
—
—
0
0
11
118
0.93
0.02
2.4
1.4
—
—
—
0
0
11
118
0.93
0.02
2.4
1.4
—
—
—
0
0
11
118
0.93
0.02
2.4
1.4
—
—
—
0
0
866
8673
0.99
0.02
25.0
16.6
13.64
13.52
%
2.06
860
8560
43
438
0.98
0.01
1.2
1.3
—
—
—
0
0
24
244
0.98
0.00
1.1
1.1
—
—
—
0
0
10
98
1.02
0.00
1.2
1.2
—
—
—
0
0
19
192
0.99
0.00
1.1
1.1
6.46
2.45
eliau/ml
—
9
97
19
189
1.01
0.00
4.5
3.7
19.77
20.13
mg/l
0.02
13
123
14
137
1.02
0.00
1.9
1.8
3.96
4.49
ug/l
—
9
110
25
253
0.99
0.00
5.2
1.9
—
—
—
0
0
51
513
0.99
0.00
1.1
1.1
—
—
—
0
0
24
245
0.98
0.00
1.1
1.1
—
—
—
0
0
6
63
0.95
0.00
1.5
1.3
72.67
70.03
umol/l
—
6
63
5
59
0.85
0.00
1.6
1.8
—
3488.00
—
0
10
0
8
0.00
0.00
0.0
2.0
—
75.51
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
66
0.91
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
70.58
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
64.00
—
0
9
6
60
1.00
-0.00
1.3
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
4249.40
—
0
5
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
8
81
0.99
-0.00
1.3
1.1
1.03
1.04
ratio
—
8
66
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
511.67
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
206.89
—
0
9
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
353.57
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
150.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
37.26
—
0
5
6
67
0.89
-0.00
1.0
1.1
—
49.00
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.6
2.3
9.86
7.78
mmol/l
—
5
54
0
6
0.00
-0.00
0.0
1.0
—
102.17
—
0
6

Mortality – FinRegistry

Association

Association between endpoint N14_VULVAL_LSIL and mortality.

Females

Parameter HR [95% CI] p-value
N14_VULVAL_LSIL 0.98 [0.83, 1.16] 0.81
Birth year 0.998 [0.99, 1.01] 0.701

During the follow-up period (1.1.1998 — 31.12.2019), 201 out of 1884 females with N14_VULVAL_LSIL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VULVAL_LSIL.

N-year risk Females Males
1 0.081% No data
5 0.557% No data
10 1.448% No data
15 2.86% No data
20 5.428% No data

Relationships between endpoints

Index endpoint: N14_VULVAL_LSIL – LSIL lesion of the vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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