All dysplastic lesions of the vulva

N14_VULVAL_DYSPLASIA_ALL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1852

4. Check minimum number of events

None

1852

5. Include endpoints

None

1852

6. Filter based on genotype QC (FinnGen only)

1671

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9508 9508 -
Only index persons 8975 8975 -
Unadjusted period prevalence (%)
Whole population 0.27 0.27 -
Only index persons 0.33 0.33 -
Median age at first event (years)
Whole population - 38.96 -
Only index persons - 38.45 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1671 1671 -
Unadjusted period prevalence (%) 0.59 0.59 -
Median age at first event (years) 42.66 42.66 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1729
Matched controls
17290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ULA02
NOMESCO Finland
Kolposcopy
12.8
307.7
952
1515
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
41.6
307.7
280
80
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
+∞
307.7
394
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
46.5
307.7
696
247
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
163.5
307.7
163
11
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
307.7
650
*
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
178.8
307.7
191
12
N90.0
ICD-10 Finland
Mild vulvar dysplasia
+∞
307.7
477
*
LEB00
NOMESCO Finland
Biopsy of vagina
17.2
305.2
265
180
LFC00
NOMESCO Finland
Partial excision of vulva
138.8
303.2
152
12
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
+∞
302.2
281
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
6.2
298.9
763
1967
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
47.2
269.7
159
37
8411
FHL
Local change laser, coagulation, biopsy or removal
114.0
228.9
117
11
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
1199.2
220.8
211
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
8.8
185.3
251
327
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
5.6
182.2
414
921
D06BB10
ATC
imiquimod; topical
7.4
174.6
280
442
N89.0
ICD-10 Finland
Mild vaginal dysplasia
32.2
162.8
106
35
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
4.3
155.3
520
1567
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
144.9
137
*
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
6.1
126.6
239
441
8326
FHL
Batch conization
34.5
119.4
76
23
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
39.1
104.1
64
17
N87.0
ICD-10 Finland
Mild cervical dysplasia
6.4
102.3
180
308
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
17.7
98.4
81
48
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
17.9
94.2
77
45
D06BB04
ATC
podophyllotoxin; topical
5.0
92.8
219
490
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
53.6
90.8
52
10
N90.4
ICD-10 Finland
Leukoplakia of vulva
20.4
84.7
65
33
LDA10
NOMESCO Finland
Curettage of cervix uteri
4.5
84.5
230
576
N76.6
ICD-10 Finland
Ulceration of vulva
10.7
73.4
81
79
D07AD01
ATC
clobetasol; topical
2.7
71.8
494
2197
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
6.3
68.1
119
201
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
4.0
66.2
208
576
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
8.6
63.7
83
101
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
619.3
61.1
60
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.2
53.2
861
5432
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
171.5
48.1
50
*
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
4.3
40.4
109
268
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
77.1
40.1
45
6
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
209.8
40.0
41
*
J02AC01
ATC
fluconazole; systemic
1.9
38.4
1020
7363
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
37.6
36
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
4.2
37.6
103
256
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
77.8
33.9
38
5
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
4.8
33.8
78
169
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.2
33.6
336
1705
1390
FHL
Colposcopy
71.3
31.0
35
5
P01AB01
ATC
metronidazole; oral, rectal
1.8
30.6
884
6370
127
Kela drug reimbursment
Transplant complication
7.0
29.3
45
66
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
24.3
27.0
38
16
L04AA06
ATC
mycophenolic acid; systemic
5.0
25.7
55
112
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
3.6
25.7
85
242
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
25.1
246
1229
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
39.5
24.9
31
8
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
28.0
24.5
33
12
G01AA10
ATC
clindamycin; vaginal
1.8
24.0
435
2685
8113
FHL
Fractional scraping
2.4
22.9
161
697
L29.2
ICD-10 Finland
Pruritus vulvae
3.7
22.8
73
203
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.5
22.7
44
82
G01AF01
ATC
metronidazole; vaginal
1.9
21.2
290
1630
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
2.4
20.9
159
713
WX002
NOMESCO Finland
Sedation and analgesia
1.8
20.5
348
2095
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
48.6
20.2
24
5
L04AD02
ATC
tacrolimus; systemic
6.8
20.0
31
46
E0000UV, ,
ATC
1.6
19.8
794
5992
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
+∞
19.8
19
*
Z94.0
ICD-10 Finland
Kidney transplant status
6.7
19.6
31
47
LFD10
NOMESCO Finland
Vulvectomy and excision of regional lymph nodes
202.2
19.6
20
*
A11CC03
ATC
alfacalcidol; systemic
4.3
19.6
50
118
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.9
19.2
42
87
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.6
19.2
65
188
N02AX02
ATC
tramadol; systemic, rectal
1.6
19.0
735
5486
N03AX16
ATC
[U] pregabalin
1.7
18.6
446
2952
A10AB01
ATC
insulin (human); parenteral
3.2
18.6
73
232
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.0
18.6
205
1066
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.0
18.0
51
130
J01MA02
ATC
ciprofloxacin; systemic
1.6
17.9
629
4574
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
17.8
522
3631
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.7
17.5
95
363
ZXC00
NOMESCO Finland
Use of diathermy
5.9
17.5
31
53
8339
FHL
Other measure in this category
14.0
17.3
29
21
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
16.7
438
2955
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
16.5
16.6
26
16
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
23.3
16.4
23
10
UKC02
NOMESCO Finland
Cystoscopy
2.0
16.3
190
1006
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
16.3
367
2379
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
16.2
523
3710
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
16.0
748
5757
C03CA01
ATC
furosemide; systemic
1.6
15.8
403
2695
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
15.8
664
4990
ZXC10
NOMESCO Finland
Use of laser
3.5
15.6
53
154
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
4.4
15.5
39
91
J01EA01
ATC
trimethoprim; systemic
1.6
15.3
564
4111
A12AA04
ATC
calcium carbonate; oral
5.1
15.3
32
64
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
15.3
701
5358
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
15.2
459
3197
J01FF01
ATC
clindamycin; systemic
1.6
15.1
475
3338
UJF32
NOMESCO Finland
Coloscopy
1.6
15.0
435
2997
D07AC01
ATC
betamethasone; topical
1.5
15.0
649
4893
Z2221
NOMESCO Finland
Medical doctor
1.6
14.8
497
3545
8070/3-C51.1
ICD-O-3
Squamous cell carcinoma, NOS, of labium minus
+∞
14.6
14
*
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
14.6
69
245
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
14.6
766
6005
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
14.5
194
1075
A02BC02
ATC
pantoprazole; systemic
1.5
14.5
1218
10503
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
14.5
331
2148
A10AA02, ,
ATC
3.1
14.3
60
199
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
14.3
219
1269
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
14.2
541
3960
TAC99
NOMESCO Finland
Other blockade for chronic pain
5.7
14.2
26
46
H3603, E103,
ICD-10 Finland
5.7
14.2
26
46
T89
ICPC
Diabetes insulin dependent
2.7
14.0
77
296
A10AA01, ,
ATC
3.2
13.9
55
176
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
24.0
13.8
19
8
A10AC01
ATC
insulin (human); parenteral
2.2
13.7
122
583
N94.1
ICD-10 Finland
Dyspareunia
3.8
13.7
42
114
A10AE04
ATC
insulin glargine; parenteral
2.1
13.6
139
701
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
13.6
71
266
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.5
13.5
1153
9888
LFD00
NOMESCO Finland
Vulvectomy
141.1
13.5
14
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
5.6
13.4
25
45
TK800
NOMESCO Finland
Hemodialysis
4.4
13.4
33
76
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.4
13.3
22
35
ZXA05
NOMESCO Finland
Left side
1.6
13.2
386
2655
Z3231
NOMESCO Finland
Registered nurse
1.6
13.2
436
3084
Z01.2
ICD-10 Finland
Dental examination
1.5
13.1
864
7030
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.6
13.1
76
301
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
12.8
128
640
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
12.7
398
2778
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
12.6
216
1291
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
12.6
548
4105
8077/2-C51.1
ICD-O-3
Squamous intraepithelial neoplasia, high grade of labium minus
+∞
12.5
12
*
2333B
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Other and unspecified female genital organs[CARCINOMA IN SITU VULVAE]
+∞
12.5
12
*
7020X
ICD-9 Finland
Other dermatoses, Actinic keratosis[DERMATOSES PRAECANCEROSAE ALIAE]
130.9
12.4
13
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
12.4
488
3577
N01BB02
ATC
lidocaine; parenteral
4.5
12.4
30
68
J01DB01
ATC
cefalexin; oral
1.6
12.3
1433
12971
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
12.2
268
1716
N30.0
ICD-10 Finland
Acute cystitis
1.6
12.2
376
2614
WX320
NOMESCO Finland
Spinalanesthesy
1.5
12.1
414
2944
L04AA01
ATC
[U] ciclosporin
3.8
12.0
36
96
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
12.0
156
857
LFC96
NOMESCO Finland
Other partial excision of vulva or perineum
65.4
11.6
13
*
R2110
NOMESCO Finland
Giving the first information
1.9
11.6
155
859
ZXE00
NOMESCO Finland
One hour or less
1.4
11.6
665
5234
LFE10
NOMESCO Finland
Plastic repair of vulva
9.3
11.5
23
25
G01AF04
ATC
miconazole; vaginal
1.9
11.5
140
752
8542/3-C51.9
ICD-O-3
Paget disease, extramammary of vulva, NOS
120.8
11.4
12
*
ZZR00
NOMESCO Finland
Flap of skin
3.4
11.4
40
119
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
11.3
302
2028
H04AA01
ATC
glucagon; nasal, parenteral
3.2
11.3
44
140
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
11.2
393
2803
M79.6
ICD-10 Finland
Pain in limb
1.4
11.2
835
6872
8070/2-C53.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of cervix uteri
5.6
11.2
21
38
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.5
11.2
69
282
H02AB06
ATC
prednisolone; systemic
1.4
11.1
810
6639
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.1
11.1
24
30
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
8.1
11.1
24
30
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
5.3
11.1
22
42
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
11.0
88
404
G04BD12
ATC
mirabegron; oral
1.7
10.9
195
1179
TQW99
NOMESCO Finland
Other minor procedure on skin
2.3
10.8
84
380
X15
ICPC
Vaginal symptom/complaint other
2.1
10.8
99
479
J01DA01
ATC
[U] cefalexin
1.4
10.8
1087
9401
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.8
300
2032
8112
FHL
Scraping the cervix
17.9
10.7
16
9
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
17.9
10.7
16
9
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
4.6
10.7
25
55
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
10.7
691
5532
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.3
10.6
21
40
E000006, ,
ATC
1.9
10.5
132
716
B01AB10
ATC
tinzaparin; parenteral
1.7
10.5
194
1185
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.8
10.4
51
185
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
10.4
197
1210
N07BA03
ATC
varenicline; oral
2.2
10.4
90
427
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.1
10.4
42
137
ZXA00
NOMESCO Finland
Right side
1.5
10.4
411
3002
A10AB04
ATC
insulin lispro; parenteral
2.6
10.3
60
238
TLC02
NOMESCO Finland
Simple extraction of IUD
1.9
10.2
121
645
R03AC02
ATC
salbutamol; inhalant
1.4
10.1
1006
8637
J01AA02
ATC
doxycycline; systemic
1.5
10.1
1375
12484
A10AB05
ATC
insulin aspart; parenteral
2.0
10.0
109
563
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
10.0
179
1082
M03BX02
ATC
tizanidine; oral
1.4
10.0
1143
10037
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.2
10.0
81
374
R4110
NOMESCO Finland
Physiotherapy
1.5
10.0
460
3456
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.9
442
3299
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
9.9
620
4921
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
9.9
286
1952
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
2.4
9.8
68
293
J05AB01
ATC
aciclovir; systemic
1.5
9.8
428
3180
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
10.7
9.8
18
17
N02BE01
ATC
paracetamol; systemic, rectal
1.7
9.8
1560
14599
J01MA12
ATC
levofloxacin; systemic
1.6
9.8
269
1815
8511
FHL
Cervical dilation and drainage with suction
2.1
9.8
98
492
J01CA08
ATC
pivmecillinam; oral
1.4
9.8
949
8095
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
9.7
451
3391
N06AX12
ATC
bupropion; oral
1.8
9.7
140
796
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
3.8
9.6
29
78
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
9.5
580
4572
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
4.8
9.5
21
44
JAH01
NOMESCO Finland
Laparoscopy
2.0
9.5
102
524
P17
ICPC
Tobacco abuse
3.6
9.5
31
88
ZXD05
NOMESCO Finland
Urgent procedure
1.4
9.5
478
3645
B03XA02
ATC
darbepoetin alfa; parenteral
3.3
9.5
35
108
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
9.4
104
540
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
9.4
77
357
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
9.3
137
782
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.3
417
3111
C539, 6666, 0
ICD-O-3
3.4
9.2
32
95
A46
ICD-10 Finland
Erysipelas
1.7
9.2
191
1203
J05AB11
ATC
valaciclovir; oral
1.5
9.2
280
1932
R42
ICD-10 Finland
Dizziness and giddiness
1.5
9.2
388
2862
LFW96
NOMESCO Finland
Other operation on vulva or perineum
15.7
9.0
14
9
C51.00
ICD-10 Finland
Malignant tumor of the labium majus without histology
36.9
9.0
11
*
L04AX01
ATC
azathioprine; systemic
2.2
9.0
77
364
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
9.0
160
967
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
9.0
92
466
X16
ICPC
Vulval symptom/complaint
2.9
8.9
41
144
ZX120
NOMESCO Finland
Intravenous
1.7
8.9
152
908
L57.0
ICD-10 Finland
Actinic keratosis
1.7
8.8
151
901
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
8.8
164
1002
A02BC05
ATC
esomeprazole; systemic
1.4
8.8
709
5833
ZXA10
NOMESCO Finland
Bilateral
1.5
8.8
296
2083
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
3.5
8.8
29
83
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
8.8
172
1066
G01AF02
ATC
clotrimazole; vaginal
2.0
8.8
101
533
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
8.8
622
5016
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
8.7
227
1509
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
7.2
8.7
20
28
137
Kela drug reimbursment
Uraemia requiring dialysis
7.2
8.7
20
28
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
8.7
230
1535
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.7
483
3737
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.8
8.7
137
799
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.6
1011
8802
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.1
8.6
81
398
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
8.5
118
661
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.4
8.5
386
2880
J02AC02
ATC
itraconazole; systemic
1.5
8.5
333
2416
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
3.4
8.5
30
90
WX892
NOMESCO Finland
Monitored bed care
1.9
8.4
99
526
N06AB04
ATC
citalopram; systemic
1.4
8.4
372
2762
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.3
127
733
N02AA05
ATC
oxycodone; systemic
1.5
8.3
249
1708
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
8.6
8.3
17
20
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.7
8.3
26
72
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.2
241
1645
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.9
8.2
38
134
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.5
8.2
28
82
H3600, E103,
ICD-10 Finland
3.7
8.2
25
68
Z29.8
ICD-10 Finland
Other specified prophylactic measures
2.2
8.1
63
286
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.1
158
979
N03AX12
ATC
[U] gabapentin; oral
1.5
8.0
278
1966
B01AB05
ATC
enoxaparin; parenteral
1.4
8.0
505
3981
L43.8
ICD-10 Finland
Other lichen planus
2.7
8.0
41
153
Z49.0
ICD-10 Finland
Preparatory care for dialysis
7.3
8.0
18
25
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.9
1131
10082
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
7.9
172
1095
1530
FHL
Urethrocystoscopy
3.7
7.9
24
65
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
7.9
78
390
N18.0
ICD-10 Finland
End-stage renal disease
6.6
7.9
19
29
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.7
7.9
18
39
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
1235
11165
LEB10
NOMESCO Finland
Excision of lesion of vagina
6.1
7.8
20
33
XKD00
NOMESCO Finland
Uroflowmetry
2.1
7.8
73
357
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.4
7.8
27
80
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
4.1
7.8
21
52
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
2.3
7.8
58
259
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
10.8
7.8
14
13
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
10.8
7.8
14
13
K59.0
ICD-10 Finland
Constipation
1.9
7.8
91
483
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.8
190
1244
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
9.4
7.8
15
16
M54.5
ICD-10 Finland
Low back pain
1.3
7.8
661
5457
6230A
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE LEVIS]
45.2
7.7
9
*
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
7.7
120
698
WZA10
NOMESCO Finland
Extensive medical or dental certificate
3.2
7.7
30
96
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
4.4
7.7
19
44
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.7
340
2522
A01AB09
ATC
miconazole; local oral
1.7
7.6
145
891
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.6
182
1185
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.6
182
1185
N30.2
ICD-10 Finland
Other chronic cystitis
3.7
7.6
23
62
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.8
7.6
118
685
G44.2
ICD-10 Finland
Tension-type headache
1.5
7.6
277
1979
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
7.6
179
1163
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
7.6
84
438
U07
ICPC
Urine symptom/complaint other
1.7
7.6
147
909
C03DA01
ATC
spironolactone; oral
1.6
7.6
159
1004
R06AE07
ATC
cetirizine; oral
1.3
7.6
814
6944
G01AF05
ATC
econazole; vaginal
1.6
7.5
202
1352
NF1AA
NOMESCO Finland
Hip X-ray examination
1.7
7.5
134
810
S20
ICPC
Corn/callosity
3.0
7.5
31
103
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.8
7.4
35
125
N06AX16
ATC
venlafaxine; oral
1.5
7.4
279
2005
K05.31
ICD-10 Finland
Periodontitis pronounced
1.6
7.4
169
1089
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.5
7.4
25
73
N76.3
ICD-10 Finland
Subacute and chronic vulvitis
2.9
7.4
34
120
R69
ICD-10 Finland
Unknown and unspecified causes of morbidity
2.9
7.4
34
120
L12
ICPC
Hand/finger symptom/complaint
1.4
7.4
313
2301
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.3
581
4734
8077/2-C51.8
ICD-O-3
Squamous intraepithelial neoplasia, high grade of overlapping lesion of vulva
+∞
7.3
7
*
C51.21
ICD-10 Finland
Squamous cell carcinoma of the clitoris
+∞
7.3
7
*
PBM09
NOMESCO Finland
Closure of arteriovenous fistula of brachial artery
+∞
7.3
7
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
7.3
78
402
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.8
7.3
104
590
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.3
599
4910
A10AE05
ATC
insulin detemir; parenteral
2.0
7.1
75
384
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.1
159
1019
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.9
7.1
33
117
D12
ICPC
Constipation
2.2
7.1
60
283
N06AX11
ATC
mirtazapine; oral
1.3
7.1
588
4821
N76.1
ICD-10 Finland
Subacute and chronic vaginitis
2.2
7.1
57
264
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
8.8
7.0
14
16
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
7.0
75
386
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
2.7
7.0
35
129
WF002
NOMESCO Finland
Radical radiotherapy
2.2
7.0
54
245
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.0
198
1341
TQW80
NOMESCO Finland
Local dermatologic skincare
2.4
7.0
45
189
3AC01, ,
NOMESCO Finland
3.7
6.9
21
57
B05DB
ATC
Hypertonic solutions
7.6
6.9
15
20
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.6
6.9
15
20
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.9
151
965
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.8
6.8
106
616
SFA20
NOMESCO Finland
Two-surface restoration
1.3
6.8
1021
9060
N76.0
ICD-10 Finland
Acute vaginitis
1.6
6.8
148
942
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
2.5
6.8
42
173
V03AE02
ATC
sevelamer; oral
9.3
6.8
13
14
D39.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other female genital organs
9.3
6.8
13
14
S20.2
ICD-10 Finland
Contusion of thorax
1.9
6.8
78
413
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.8
6.7
33
121
S06.0
ICD-10 Finland
Concussion
1.6
6.7
165
1083
K30
ICD-10 Finland
Functional dyspepsia
1.5
6.7
214
1488
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.7
6.6
20
54
SPAT1262
SPAT
Handing over of treatment supplies
1.5
6.6
216
1507
C07AB07
ATC
bisoprolol; oral
1.3
6.6
672
5655
H02AB04
ATC
methylprednisolone; systemic
1.5
6.6
238
1696
J01MA06
ATC
norfloxacin; oral
1.5
6.6
242
1731
D07AC13
ATC
mometasone; topical
1.3
6.5
470
3763
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.5
330
2498
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.5
220
1545
ZXD20
NOMESCO Finland
Day surgery
1.5
6.5
220
1546
R51.80
ICD-10 Finland
Headache
1.4
6.5
299
2227
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.5
123
756
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
6.5
62
307
K08.80
ICD-10 Finland
Toothache NOS
1.6
6.5
172
1148
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.2
6.5
16
26
A07AA09
ATC
vancomycin; oral
3.2
6.4
24
75
R15
ICD-10 Finland
Faecal incontinence
2.1
6.4
60
295
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.4
180
1218
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
6.4
232
1655
N05BA04
ATC
oxazepam; oral
1.3
6.4
446
3557
N81.6
ICD-10 Finland
Rectocele
1.6
6.3
149
968
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.3
6.3
45
198
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.3
301
2256
M01AH05
ATC
etoricoxib; oral
1.3
6.3
1103
9942
X23
ICPC
Fear sexually transm dis female
1.8
6.3
85
474
A02BC03
ATC
lansoprazole; oral
1.3
6.3
461
3698
J20
ICD-10 Finland
Acute bronchitis
1.5
6.3
185
1263
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
6.0
6.3
16
27
WZC30
NOMESCO Finland
Teaching
1.4
6.3
250
1813
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.3
98
571
H3603, E107,
ICD-10 Finland
18.1
6.3
9
5
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
6.2
869
7602
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.2
1242
11386
H02AB07
ATC
prednisone; oral
1.5
6.2
219
1552
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.2
315
2385
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.2
936
8267
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.6
6.2
125
781
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.3
6.2
445
3558
M01AE02
ATC
naproxen; oral, rectal
1.3
6.2
978
8688
D07AB08
ATC
desonide; topical
1.5
6.2
172
1160
H3601, E103,
ICD-10 Finland
5.0
6.2
18
36
N05CD07
ATC
temazepam; oral
1.6
6.2
153
1006
SDA03
NOMESCO Finland
Periodontal treatment
1.3
6.2
713
6087
WX402
NOMESCO Finland
General anaesthesia
1.4
6.2
371
2889
N06AX21
ATC
duloxetine; oral
1.5
6.1
235
1692
Z3226
NOMESCO Finland
Physiotherapist
1.4
6.1
280
2082
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
6.1
107
645
JN3AD
NOMESCO Finland
Abdominal CT examination
1.5
6.1
194
1348
A02BC01
ATC
omeprazole; systemic
1.3
6.1
414
3286
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
6.0
148
971
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
10.1
6.0
11
11
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.0
6.0
65
337
Z2446
NOMESCO Finland
Social worker
1.7
6.0
97
571
S18
ICPC
Laceration/cut
1.3
6.0
718
6149
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.7
6.0
98
579
A07AA02
ATC
nystatin; oral
1.7
6.0
96
564

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
342
419
9.93
268.36
3.2
1.8
—
—
—
0
0
1085
7152
2.39
64.74
3.9
2.1
—
—
—
0
0
54
44
12.64
54.88
1.8
1.8
6.19
1.93
ug/l
0.47
37
24
316
1425
2.49
42.31
1.6
1.4
—
—
—
0
0
723
5071
1.73
26.13
2.9
2.2
—
—
—
0
0
380
2221
1.91
25.07
1.4
1.3
—
—
—
0
0
673
4749
1.68
22.97
4.7
3.2
36.37
62.11
e6/l
0.76
532
3533
735
5325
1.66
22.55
8.0
6.1
—
—
—
0
0
311
1758
1.94
22.45
2.4
1.7
—
—
—
0
0
561
3831
1.69
21.31
2.7
2.2
—
—
—
0
0
908
7008
1.62
21.15
6.7
4.4
35.93
36.31
g/l
1.44
882
6601
211
1067
2.11
20.69
11.3
6.6
8.59
8.44
mmol/l
0.15
201
1028
374
2297
1.80
20.62
3.8
2.9
4.55
4.53
e6/l
0.01
204
1012
900
6966
1.61
20.45
8.3
5.6
1.22
1.22
mmol/l
0.50
845
6465
759
5679
1.60
19.58
5.7
3.8
71.10
90.66
e6/l
0.66
567
3807
388
2446
1.76
19.44
4.0
3.1
0.80
0.82
mmol/l
1.61
375
2309
1235
10389
1.66
19.44
6.4
4.7
1642.80
2948.49
e6/l
—
10
127
583
4109
1.63
19.14
4.6
3.0
0.25
0.37
e6/l
2.12
445
2919
981
7845
1.58
18.68
9.1
6.3
1.22
1.22
mmol/l
1.53
880
6828
928
7352
1.57
18.22
3.3
2.6
—
—
estimate
—
0
0
1026
8321
1.57
18.13
7.2
6.1
9.37
10.08
umol/l
1.80
997
7947
702
5234
1.57
17.91
3.8
3.1
—
—
—
0
0
1021
8292
1.56
17.76
8.6
6.2
0.55
0.54
e9/l
0.86
914
7200
673
4992
1.57
17.43
3.2
2.4
53.93
58.45
u/l
1.56
638
4626
303
1839
1.79
17.09
9.7
4.7
1.08
1.04
mmol/l
1.51
282
1684
1036
8485
1.55
17.00
8.6
6.2
1.92
1.95
e9/l
0.33
960
7545
1018
8309
1.55
16.94
8.6
6.2
0.04
0.04
e9/l
0.39
912
7207
1046
8596
1.55
16.81
8.8
6.4
0.19
0.18
e9/l
0.53
964
7570
390
2556
1.68
16.66
3.6
2.7
1.58
1.19
e6/l
0.59
220
1279
325
2032
1.74
16.49
2.7
1.9
—
—
—
0
0
1113
9331
1.54
15.85
12.6
9.4
3.94
3.93
e9/l
0.03
996
8158
1378
12157
1.66
15.57
10.5
7.9
76.98
77.03
u/l
0.02
1317
11575
945
7671
1.51
15.51
8.4
6.1
57.27
56.63
%
0.97
901
7345
465
3237
1.60
15.44
3.8
2.6
8.39
7.97
e6/l
0.15
427
2946
936
7597
1.51
15.27
8.8
6.3
8.47
8.43
%
0.19
878
7153
954
7794
1.50
14.93
8.7
6.2
28.37
29.02
%
1.16
911
7422
405
2747
1.62
14.91
4.3
2.8
474.43
495.68
mosm/kgh2o
1.29
370
2401
366
2422
1.65
14.87
1.2
1.2
—
—
—
0
0
1041
8668
1.51
14.78
5.1
4.0
0.00
0.01
estimate
2.11
194
1710
930
7585
1.49
14.50
8.8
6.3
0.67
0.71
%
1.26
873
7111
148
752
2.06
14.22
1.3
1.2
—
—
—
0
0
928
7583
1.48
14.21
8.7
6.2
2.81
2.79
%
0.13
872
7129
246
1478
1.77
14.20
2.6
2.0
0.21
0.22
g/l
0.41
235
1391
544
4002
1.52
13.87
5.5
3.5
97.19
96.08
%
0.51
529
3897
495
3583
1.53
13.55
5.1
4.0
—
—
—
0
0
97
424
2.36
13.50
3.6
3.0
1.54
1.41
mg/l
0.87
89
392
1015
8499
1.47
13.35
5.0
4.0
0.00
0.00
estimate
0.80
195
1721
795
6366
1.46
13.10
13.6
11.4
1.16
1.16
inr
0.01
653
5236
192
1102
1.84
12.86
10.2
7.8
—
—
—
0
0
529
3937
1.50
12.51
3.1
3.0
1074.28
839.36
ng/l
0.48
458
3333
1018
8595
1.45
12.36
5.0
4.0
9.39
3.37
estimate
0.28
200
1782
282
1827
1.65
12.26
1.7
1.5
—
—
—
0
0
1351
12095
1.54
11.91
5.7
4.5
12.66
11.71
mm/h
1.77
1285
11419
22
40
5.56
11.65
2.9
2.5
0.59
0.62
mmol/l
1.27
22
40
145
790
1.91
11.41
4.1
3.2
5.10
5.21
kpa
1.09
138
762
637
4984
1.44
11.40
4.8
3.2
6.49
6.80
mmol/l
1.22
535
4259
1032
8820
1.42
11.16
6.4
4.4
6.66
6.48
mmol/l
1.55
984
8318
494
3710
1.46
10.88
1.5
1.5
2.12
2.22
g/l
0.64
297
2318
635
5005
1.42
10.76
8.6
5.9
—
—
—
0
0
139
768
1.88
10.48
4.0
3.2
7.41
7.42
ph
0.34
110
645
301
2066
1.55
10.15
2.6
2.0
29.18
29.17
s
0.01
294
2002
592
4654
1.41
10.00
4.7
3.3
55.79
34.52
mg/l
1.09
373
2684
826
6873
1.39
9.96
4.3
3.5
6.30
6.24
ph
0.68
459
3941
356
2552
1.50
9.77
3.7
2.4
12.92
13.35
umol/l
0.53
335
2386
205
1300
1.65
9.59
5.4
3.1
5.84
5.82
kpa
0.12
198
1268
146
843
1.80
9.57
3.4
2.0
13.59
8.07
iu/ml
0.79
43
202
330
2340
1.51
9.53
3.8
2.3
2.32
2.42
g/l
2.62
303
2167
276
1883
1.55
9.52
2.8
2.4
5.71
6.25
umol/l
0.36
238
1643
554
4335
1.41
9.51
1.8
1.7
21.52
21.36
nmol/l
0.08
495
3719
204
1295
1.65
9.51
5.4
3.1
7.38
7.38
ph
0.29
128
710
199
1257
1.66
9.45
5.5
3.1
1.81
1.96
mmol/l
0.21
173
1104
826
6916
1.37
9.38
2.4
2.1
99.53
99.53
pmol/l
0.00
429
3462
20
41
4.92
9.32
1.8
1.5
—
—
—
0
0
303
2120
1.52
9.30
4.0
2.4
21.26
22.27
%
0.84
280
1975
135
768
1.82
9.29
8.7
8.6
24.17
24.46
mmol/l
0.50
130
753
198
1258
1.65
9.19
3.7
3.0
10.05
10.47
g/l
0.70
184
1164
592
4712
1.39
9.11
5.5
3.9
10.42
7.01
mg/mmol
0.81
364
2691
332
2386
1.48
8.93
1.8
1.7
1205.64
1185.84
nmol/l
0.14
272
1811
602
4820
1.38
8.89
6.2
3.8
7.40
7.40
ph
0.17
444
3408
236
1581
1.57
8.80
2.6
2.1
0.00
0.03
estimate
1.30
34
336
97
508
1.96
8.61
1.4
1.4
328.31
303.95
ug/g
0.45
58
287
199
1291
1.61
8.49
5.2
3.2
100.72
75.39
ng/l
2.40
177
1124
248
1696
1.54
8.42
2.3
2.1
374.29
377.06
nmol/l
0.07
230
1570
199
1296
1.61
8.35
7.9
7.8
96.06
96.15
%
0.07
192
1252
222
1484
1.57
8.34
7.5
7.3
0.66
1.18
mmol/l
1.16
187
1216
493
3853
1.39
8.31
1.9
1.8
0.95
0.97
mg/l
0.09
390
2959
935
8076
1.34
8.24
3.1
2.5
78.98
78.67
nmol/l
0.12
853
7440
157
966
1.69
8.24
1.3
1.2
—
—
—
0
0
190
1228
1.61
8.23
1.4
1.4
—
—
—
0
0
100
538
1.91
8.21
4.0
3.1
—
—
—
0
0
598
4835
1.36
8.14
3.6
3.0
0.33
0.02
0.71
12
97
101
547
1.90
8.13
2.4
1.9
1.64
1.54
g/l
0.42
85
480
522
4146
1.37
7.90
2.6
2.3
2.98
2.78
mg/l
0.88
463
3600
334
2466
1.44
7.72
2.1
2.3
154.69
107.56
ug/g
1.03
259
1961
220
1495
1.54
7.67
7.9
7.3
5.13
5.13
kpa
0.04
214
1436
220
1495
1.54
7.67
7.9
7.3
13.02
12.97
kpa
0.05
213
1435
280
2005
1.47
7.59
1.6
1.4
—
—
—
0
0
182
1189
1.59
7.53
8.6
6.7
1.14
1.24
mmol/l
1.13
177
1169
1619
15455
1.75
7.47
21.9
14.2
20.49
20.25
mg/l
0.11
1387
12563
707
5919
1.33
7.45
4.2
3.4
2.36
2.36
mmol/l
0.34
642
5446
219
1498
1.53
7.40
7.9
7.3
7.42
7.42
ph
0.03
113
832
218
1495
1.52
7.28
3.1
2.6
1.89
1.85
%
0.25
195
1329
167
1083
1.60
7.13
4.4
2.6
4.75
4.51
kpa
0.56
157
1054
92
508
1.86
7.01
1.3
1.2
—
—
—
0
0
90
494
1.87
6.99
1.2
1.2
—
—
—
0
0
61
292
2.13
6.96
1.7
1.3
—
—
—
0
0
1628
15599
1.75
6.94
23.5
15.7
139.58
139.74
mmol/l
1.94
1611
15335
360
2742
1.40
6.91
1.5
1.4
594.22
569.34
titre
0.10
90
608
195
1320
1.54
6.91
3.4
3.5
4.47
4.49
pmol/l
0.05
169
1190
225
1572
1.50
6.87
2.8
2.4
31.71
38.36
u/l
1.71
182
1319
79
419
1.93
6.81
5.3
3.1
1.70
1.97
index
0.16
44
207
334
2526
1.40
6.67
1.8
1.6
—
—
—
0
0
758
6483
1.30
6.59
4.7
3.8
3.92
0.13
estimate
0.59
154
1397
1209
11008
1.33
6.58
3.8
3.2
44.32
39.62
u/l
1.21
1166
10444
562
4619
1.32
6.53
5.2
4.1
0.00
0.00
estimate
1.34
185
1673
153
993
1.59
6.52
1.9
1.8
1.44
1.38
g/l
0.11
140
916
56
267
2.13
6.47
1.7
1.3
160.54
158.48
au/ml
0.05
18
76
826
7164
1.29
6.39
13.8
10.4
0.00
0.00
e9/l
0.09
697
5839
666
5618
1.30
6.36
4.1
3.0
31.63
30.17
u/l
0.26
636
5343
487
3934
1.33
6.36
2.9
2.3
312.98
309.16
umol/l
0.35
440
3515
51
236
2.20
6.36
2.3
2.4
31.35
33.25
umol/l
0.24
46
218
167
1115
1.55
6.30
2.7
2.7
72.27
73.47
e9/l
0.15
125
798
359
2772
1.37
6.30
4.1
3.5
117.99
325.95
ng/l
2.60
239
1884
418
3310
1.35
6.23
3.0
2.7
2.45
2.45
mmol/l
0.14
360
2982
1627
15634
1.69
6.22
24.1
15.8
3.93
3.93
mmol/l
0.44
1611
15329
1442
13523
1.40
6.22
5.7
5.1
14.73
14.60
pmol/l
1.38
1362
12702
123
768
1.65
6.14
2.6
2.1
0.00
0.01
estimate
0.80
34
255
569
4721
1.31
6.09
2.4
2.1
119.91
161.17
u/l
1.69
543
4492
169
1145
1.53
5.97
3.0
2.4
0.33
0.54
e6/l
0.79
161
1083
260
1918
1.42
5.96
1.4
1.3
—
—
—
0
0
373
2929
1.35
5.83
2.1
1.8
—
—
—
0
0
118
743
1.63
5.71
2.0
1.9
1884.30
5049.02
u/l
1.28
43
291
191
1347
1.47
5.56
2.9
2.6
5.99
6.11
ph
1.21
124
862
1578
15112
1.51
5.45
7.1
6.2
1.80
1.84
mu/l
0.62
1498
14299
57
295
1.96
5.34
1.4
1.2
305.76
266.33
u/ml
0.51
44
187
1674
16278
1.89
5.27
15.8
11.8
23.80
23.98
u/l
0.21
1652
15929
16
44
3.66
5.21
1.5
1.5
7.45
7.02
mmol/l
0.13
16
44
15
31
4.87
5.12
5.5
4.4
—
—
—
0
0
598
5082
1.27
5.11
3.8
3.2
—
0.79
—
0
14
143
972
1.51
5.00
2.4
3.1
196.14
158.80
ng/l
0.42
128
877
527
4421
1.28
4.98
1.4
1.3
1.60
1.45
u/ml
0.07
142
1196
637
5480
1.26
4.85
4.1
3.3
22.19
46.73
ng/l
1.03
397
3306
78
464
1.71
4.73
3.1
3.1
1027.56
292.13
mg/l
0.53
36
164
947
8532
1.24
4.72
3.8
3.2
102.83
83.77
ug/l
2.53
895
8085
1675
16330
1.82
4.63
26.3
18.0
71.22
68.37
umol/l
2.68
1662
16175
451
3748
1.28
4.54
5.0
4.1
1.02
1.42
kg/l
0.50
309
2491
237
1805
1.36
4.47
5.0
4.7
32.46
33.10
%
0.37
164
1242
21
76
2.78
4.45
6.1
3.1
0.71
0.76
index
0.10
21
76
105
685
1.57
4.44
4.4
2.6
0.63
0.62
%
0.13
105
680
119
801
1.52
4.38
1.4
1.3
0.52
0.98
u/ml
0.51
13
61
86
539
1.63
4.31
1.4
1.2
—
—
—
0
0
142
996
1.46
4.28
2.2
2.2
3.48
5.82
ug/l
2.46
125
869
1530
14675
1.37
4.20
4.6
4.1
1.30
1.24
mmol/l
2.66
1436
13707
24
97
2.49
4.14
3.1
3.3
347.88
37.15
mg/l
0.52
14
62
66
391
1.72
4.10
1.3
1.4
—
10.88
—
0
9
25
104
2.42
4.06
1.8
1.9
16.04
15.11
%
0.14
25
99
31
142
2.20
4.06
5.3
2.9
12.62
11.79
index
0.24
21
76
8
10
8.03
4.06
4.6
15.3
5.43
4.77
mmol/l
—
8
10
1518
14559
1.35
4.02
7.4
5.8
39.24
38.42
mmol/mol
2.88
1449
13776
20
75
2.69
3.99
2.3
2.7
39.33
46.16
%
—
9
45
60
350
1.74
3.95
1.9
2.2
—
—
—
0
0
11
23
4.81
3.87
1.9
3.9
—
—
—
0
0
15
49
3.08
3.81
1.7
1.3
—
—
—
0
0
26
115
2.28
3.72
1.2
1.4
15.55
10.46
umol/l
1.62
26
108
14
40
3.52
3.60
1.5
1.7
0.23
0.17
e9/l
—
7
21
25
111
2.27
3.55
1.8
1.9
73.76
73.79
%
0.00
25
103
90
605
1.51
3.39
2.7
1.8
20.56
20.71
s
0.12
78
523
95
646
1.50
3.39
1.3
1.3
38.58
39.99
u/ml
—
6
42
83
549
1.54
3.37
1.7
1.7
—
—
—
0
0
15
53
2.85
3.36
1.7
1.7
32.13
27.87
%
0.59
15
48
70
447
1.59
3.32
2.1
2.2
10.80
12.24
mg/l
0.75
64
418
1701
16747
1.97
3.27
32.0
22.0
91.29
90.96
fl
2.29
1693
16624
1701
16748
1.97
3.25
32.0
22.0
30.26
30.16
pg
1.71
1693
16625
1701
16748
1.97
3.25
32.1
22.0
4.38
4.42
e12/l
3.67
1679
16439
1701
16748
1.97
3.25
32.7
22.4
39.56
40.06
%
1.08
1692
16618
1701
16751
1.95
3.20
32.1
22.1
6.69
6.59
e9/l
0.99
1680
16437
770
6968
1.19
3.16
2.1
1.9
1.36
1.35
mmol/l
0.10
664
6010
44
252
1.77
3.14
1.6
1.3
—
—
—
0
0
1701
16755
1.94
3.13
32.4
22.2
131.61
132.55
g/l
2.56
1693
16628
17
67
2.55
3.13
3.1
3.4
—
—
—
0
0
1700
16744
1.91
3.10
32.2
22.1
267.19
266.40
e9/l
0.20
1684
16484
536
4703
1.20
3.08
4.0
3.3
1.80
0.24
estimate
0.46
153
1382
84
569
1.50
3.08
1.3
1.6
0.30
0.30
mg/l
0.03
39
232
89
611
1.48
3.06
4.2
2.0
1.15
1.19
g/l
0.61
89
581
60
377
1.61
3.06
1.3
1.2
—
—
—
0
0
106
756
1.43
3.00
2.2
2.0
—
—
—
0
0
87
599
1.48
2.96
1.4
1.3
14.41
6.94
u/ml
0.41
12
62
19
82
2.33
2.91
1.6
1.6
2.25
2.04
umol/l
0.33
14
74
188
1482
1.30
2.83
4.3
3.7
7.35
7.36
ph
0.20
140
1054
68
449
1.54
2.83
1.2
1.1
—
—
—
0
0
195
1550
1.29
2.76
1.2
1.2
—
—
—
0
0
5
6
8.35
2.75
1.2
1.5
60.26
15.77
mg/mmol
—
5
6
129
969
1.36
2.72
2.3
2.4
—
—
—
0
0
26
132
1.98
2.71
1.5
1.2
—
—
—
0
0
86
603
1.45
2.69
1.4
1.4
7.91
10.99
u/ml
0.27
17
106
22
105
2.11
2.69
1.0
1.2
—
—
—
0
0
180
1422
1.30
2.68
4.7
4.6
0.78
1.04
%
0.78
56
381
82
571
1.46
2.66
3.3
1.5
—
—
—
0
0
76
523
1.47
2.63
3.3
1.6
—
—
—
0
0
13
49
2.67
2.62
1.2
1.2
27.23
28.90
s
0.50
13
49
13
49
2.67
2.62
4.8
1.6
—
—
—
0
0
82
574
1.45
2.60
3.3
1.5
—
—
—
0
0
173
1368
1.29
2.56
4.8
4.7
0.04
0.12
%
1.60
49
324
151
1177
1.31
2.49
2.4
2.7
65.49
67.13
g/l
1.33
130
1092
52
334
1.57
2.48
2.4
2.1
121.00
128.78
g/l
1.52
36
263
41
248
1.67
2.47
5.2
1.8
—
—
—
0
0
43
264
1.64
2.46
3.1
2.5
105.87
96.53
ug/min
0.05
28
168
17
76
2.25
2.44
3.1
3.2
—
—
—
0
0
80
569
1.43
2.36
3.4
1.5
—
—
—
0
0
56
371
1.53
2.35
3.1
3.5
1.26
3.28
ratio
1.27
35
209
105
784
1.36
2.33
6.7
6.8
24.81
24.67
mmol/l
0.15
100
745
43
268
1.62
2.33
6.1
3.3
—
—
—
0
0
79
562
1.43
2.33
3.5
1.5
—
—
—
0
0
10
34
2.95
2.28
1.0
1.0
—
—
—
0
0
43
270
1.61
2.27
1.1
1.3
—
0.36
nmol/l
—
0
11
65
449
1.47
2.24
1.5
1.4
35.18
30.69
u/l
0.49
56
369
38
232
1.65
2.24
1.2
1.3
0.18
0.25
nmol/l
0.35
25
174
440
3895
1.17
2.20
1.4
1.4
23.73
27.61
iu/ml
0.51
124
1213
191
1563
1.25
2.17
3.5
4.1
3.46
12.14
ug/l
2.17
152
1225
68
478
1.44
2.16
10.6
8.1
—
—
—
0
0
1585
15488
1.28
2.16
5.7
4.9
4.81
4.88
mmol/l
1.90
1511
14669
64
446
1.45
2.13
3.7
1.5
—
—
—
0
0
45
291
1.56
2.12
2.0
1.4
49.69
60.32
mmol/l
1.37
39
234
1147
10907
1.15
2.10
4.5
3.6
—
0.35
—
0
20
34
206
1.66
2.08
2.8
3.1
1.87
1.67
%
0.10
34
190
370
3244
1.18
2.07
1.7
1.7
474.35
34887552.88
pmol/l
3.39
316
2746
167
1358
1.25
2.02
4.6
4.4
0.38
0.76
%
1.34
48
364
10
38
2.64
2.00
1.0
1.1
—
—
—
0
0
614
6692
0.87
2.00
3.2
3.0
—
—
—
0
0
170
1387
1.25
2.00
5.0
4.9
0.02
0.34
%
0.66
43
305
1538
14997
1.23
1.99
5.8
4.9
5.87
5.77
mmol/l
2.72
1445
14009
30
178
1.70
1.99
1.7
1.7
63.50
53.62
%
0.61
20
102
1598
15653
1.28
1.95
6.4
5.6
2.80
2.85
mmol/l
1.85
1512
14779
28
165
1.71
1.91
2.3
1.8
4.54
28.23
u/ml
0.53
28
165
59
417
1.43
1.86
1.4
1.2
—
—
—
0
0
5
12
4.18
1.82
7.0
1.4
—
—
—
0
0
9
35
2.58
1.80
1.1
1.2
—
—
—
0
0
1574
15412
1.24
1.78
5.6
4.9
1.55
1.58
mmol/l
2.29
1489
14523
52
363
1.45
1.76
3.9
3.3
58.74
58.59
%
0.03
52
363
30
185
1.63
1.76
2.3
2.2
—
—
—
0
0
6
18
3.34
1.74
1.0
1.1
—
—
—
0
0
43
290
1.50
1.73
1.4
1.6
0.80
0.64
g/l
0.43
37
234
39
258
1.52
1.71
1.1
1.1
—
—
—
0
0
59
424
1.41
1.71
3.1
3.6
37.89
50.43
mg/l
0.61
51
374
59
425
1.40
1.69
3.1
3.5
37.98
44.20
mg/l
0.20
52
373
31
195
1.60
1.69
1.5
1.6
21.70
21.39
ng/l
0.02
31
195
34
219
1.56
1.68
1.2
1.3
—
—
nmol/l
—
0
0
66
486
1.37
1.67
1.3
1.2
242.86
111.50
titre
—
7
40
23
134
1.73
1.66
1.7
1.5
6410.79
78340.65
e6/l
0.80
14
86
138
1678
0.81
1.65
1.3
1.3
—
—
—
0
0
10
41
2.45
1.64
1.0
1.3
338.30
328.22
pmol/l
—
10
32
30
189
1.60
1.63
1.1
1.1
—
—
—
0
0
18
98
1.85
1.62
1.4
1.4
72080.50
163808.80
e6/l
0.43
12
51
29
182
1.60
1.60
1.4
1.5
—
—
—
0
0
483
4400
1.14
1.59
1.5
1.5
—
—
—
0
0
158
1315
1.22
1.58
1.4
1.3
221.29
149.83
u/ml
0.38
148
1225
69
517
1.35
1.58
1.9
2.3
9.50
10.10
g/l
0.42
59
473
42
288
1.47
1.58
2.3
1.7
—
—
—
0
0
81
622
1.32
1.58
1.7
1.6
279.71
310.21
mu/l
0.67
72
563
252
2191
1.18
1.57
3.4
3.1
4.74
4.33
e9/l
0.45
222
1937
22
129
1.71
1.57
1.8
1.8
—
—
—
0
0
40
273
1.48
1.54
1.1
1.1
—
—
—
0
0
35
233
1.51
1.52
1.1
1.2
—
—
—
0
0
17
93
1.84
1.51
1.6
1.8
—
—
—
0
0
57
418
1.38
1.50
1.0
1.1
—
—
—
0
0
40
275
1.47
1.50
1.3
1.2
2.05
4.10
u/ml
1.10
21
105
54
393
1.39
1.49
3.8
2.1
—
—
—
0
0
184
1570
1.19
1.44
1.2
1.2
157.68
150.41
u/ml
0.09
61
639
38
261
1.47
1.44
8.4
3.3
2.37
2.85
mmol/l
0.45
28
184
17
95
1.80
1.43
1.6
1.5
—
—
—
0
0
9
40
2.26
1.40
1.0
1.2
—
—
—
0
0
13
67
1.95
1.38
1.2
1.3
—
—
—
0
0
64
487
1.33
1.36
1.0
1.1
31.59
5.43
eliau/ml
—
8
75
399
3626
1.13
1.35
1.4
1.3
7.54
10.19
u/ml
0.48
158
1454
56
741
0.75
1.35
1.2
1.1
1.64
1.62
g/l
0.23
56
741
88
702
1.27
1.32
1.4
1.3
204.51
227.55
miu/ml
0.27
40
357
28
184
1.53
1.32
1.3
1.5
8.92
6.55
g/l
1.25
23
139
212
1847
1.17
1.32
1.7
1.7
—
—
—
0
0
21
129
1.64
1.30
1.0
1.1
—
—
—
0
0
109
894
1.23
1.30
1.1
1.1
—
—
—
0
0
8
34
2.36
1.29
1.0
1.0
7.40
6.49
u/ml
—
8
34
36
251
1.44
1.29
1.2
1.1
—
—
—
0
0
5
18
2.78
1.28
6.0
10.9
0.16
0.20
%
—
5
18
176
2036
0.85
1.28
1.9
1.9
3.27
3.28
ratio
0.05
124
1527
20
122
1.65
1.27
1.6
1.7
38.47
39.09
%
0.02
15
66
21
130
1.62
1.27
2.5
2.7
—
—
—
0
0
90
725
1.25
1.26
1.6
1.6
10.84
13.75
u/ml
0.27
17
174
52
390
1.34
1.24
1.9
1.4
20.11
28.73
e6/l
0.16
38
282
33
229
1.45
1.22
3.6
3.8
0.80
0.78
nmol/l
0.06
25
187
132
1556
0.84
1.20
1.6
1.7
3.61
3.52
mmol/l
0.42
78
1063
155
1328
1.18
1.19
2.3
2.5
22.71
21.48
au/ml
0.07
18
165
53
692
0.76
1.19
1.2
1.1
0.60
0.62
ratio
—
6
88
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
177
1537
1.17
1.16
1.7
1.7
—
—
—
0
0
30
207
1.46
1.15
1.3
1.3
7.28
7.36
mmol/l
0.06
25
181
13
72
1.81
1.15
2.8
2.3
29.49
128.49
ug/l
0.44
13
65
52
396
1.32
1.14
1.9
1.4
302.74
1397.99
e6/l
0.86
43
307
93
764
1.23
1.12
4.1
3.2
1.02
1.02
ratio
0.32
88
680
8
40
2.00
1.12
2.5
1.2
—
—
—
0
0
19
119
1.60
1.11
3.2
3.6
—
—
—
0
0
5
21
2.38
1.09
1.0
1.0
5.68
5.24
nmol/l
—
5
21
7
32
2.19
1.08
1.4
1.5
31.14
43.58
%
—
7
25
142
1221
1.18
1.07
1.3
1.3
33.53
43.72
au/ml
—
6
79
100
834
1.21
1.05
2.4
2.3
—
—
—
0
0
11
60
1.84
1.03
1.8
2.1
29.91
28.70
%
0.10
11
60
50
386
1.30
1.02
2.3
1.7
9936.64
10392.90
e6/l
0.05
44
258
421
3905
1.10
0.99
5.7
4.6
—
—
—
0
0
29
206
1.41
0.99
1.6
1.6
315.27
378.13
mu/l
0.69
22
165
38
283
1.35
0.99
1.1
1.1
4.31
3.24
eliau/ml
0.18
19
140
28
198
1.42
0.98
2.0
1.9
8.07
5.42
umol/l
0.59
21
134
17
108
1.58
0.96
1.5
1.2
0.53
0.57
ratio
—
8
63
149
1303
1.16
0.93
1.3
1.3
—
—
—
0
0
27
193
1.41
0.90
1.9
1.4
—
—
—
0
0
27
193
1.41
0.90
1.9
1.4
—
—
—
0
0
27
193
1.41
0.90
1.9
1.4
—
—
—
0
0
27
193
1.41
0.90
1.9
1.4
—
—
—
0
0
58
469
1.24
0.85
2.1
1.9
0.89
1.85
ug/l
0.77
50
417
226
2047
1.12
0.85
1.5
1.4
—
—
—
0
0
60
732
0.81
0.83
1.4
1.6
1173.49
1004.15
mu/l
0.57
45
593
22
154
1.43
0.83
2.0
2.5
—
—
—
0
0
6
32
1.88
0.82
2.5
2.3
22.52
19.67
umol/l
—
6
32
46
365
1.27
0.80
2.0
1.4
—
—
—
0
0
17
114
1.50
0.79
1.1
1.2
—
—
—
0
0
22
158
1.40
0.74
1.3
1.3
—
—
—
0
0
12
76
1.58
0.71
1.3
1.5
144.58
151.29
mmol/24h
0.10
12
76
20
143
1.40
0.70
1.1
1.2
32.09
31.30
mg/l
0.06
13
119
39
310
1.26
0.69
1.1
1.2
—
—
—
0
0
5
27
1.85
0.68
2.2
1.6
—
—
—
0
0
22
161
1.37
0.68
3.0
2.5
—
—
—
0
0
45
366
1.24
0.67
1.1
1.3
18.42
16.38
u/l
0.29
37
296
21
154
1.37
0.65
2.8
2.2
1.26
0.91
g/24h
0.44
13
86
61
514
1.19
0.65
3.2
3.3
42.02
547.89
u/ml
1.20
48
449
17
120
1.42
0.64
1.0
1.2
—
—
—
0
0
22
163
1.35
0.64
2.9
2.7
—
—
—
0
0
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
12
79
1.52
0.62
1.2
1.6
60.67
423.70
nmol/24h
0.52
12
79
36
288
1.26
0.62
1.9
1.5
—
—
—
0
0
5
30
1.67
0.61
1.0
1.0
—
—
—
0
0
44
362
1.22
0.60
2.4
2.0
4.77
5.09
mmol/24h
0.27
39
322
11
72
1.53
0.59
1.2
1.2
—
—
—
0
0
14
97
1.45
0.59
1.6
1.4
65.50
70.37
umol/l
0.59
14
97
6
35
1.72
0.57
1.0
1.3
59.50
65.69
ug/l
—
6
35
17
124
1.37
0.55
1.6
2.3
2.17
1.84
u/field
0.12
12
74
16
116
1.38
0.54
1.5
1.5
5.13
5.67
u/l
—
10
105
6
38
1.58
0.54
1.7
1.6
—
—
—
0
0
26
328
0.79
0.54
1.0
1.1
1.49
0.92
u/ml
—
8
153
139
1266
1.11
0.52
5.5
3.9
—
—
—
0
0
59
508
1.17
0.52
1.2
1.3
31.35
42.31
u/ml
—
6
57
22
170
1.30
0.51
1.5
2.0
0.96
0.91
%
0.12
15
104
9
64
1.41
0.51
1.4
2.3
15.39
16.30
%
—
9
64
173
1597
1.09
0.50
1.3
1.4
31.22
32.09
iu/l
0.11
142
1391
113
1247
0.90
0.49
1.6
1.8
—
—
—
0
0
28
225
1.25
0.49
1.6
1.5
—
—
—
0
0
27
332
0.81
0.47
1.3
1.4
—
—
—
0
0
67
590
1.14
0.46
2.3
2.1
2.66
13.18
iu/l
0.60
31
252
7
49
1.43
0.46
1.0
1.1
—
—
—
0
0
13
94
1.39
0.46
1.5
1.2
—
—
—
0
0
7
50
1.40
0.45
1.6
1.2
—
—
—
0
0
27
220
1.23
0.43
1.2
1.1
—
—
—
0
0
5
32
1.56
0.42
3.2
3.4
—
—
—
0
0
27
327
0.82
0.42
1.3
1.4
1.39
1.27
mm
0.68
17
226
35
413
0.84
0.41
1.3
1.4
0.24
0.35
nmol/l
1.22
27
313
0
16
0.00
0.41
0.0
1.1
—
74.00
—
0
16
36
305
1.18
0.41
5.2
4.1
—
—
—
0
0
0
18
0.00
0.40
0.0
6.5
—
5.06
—
0
18
13
97
1.34
0.39
1.8
1.4
—
—
—
0
0
7
106
0.66
0.39
1.4
1.5
57.00
87.45
ng/l
—
7
106
16
124
1.29
0.38
3.9
1.9
25.59
8.83
ug/l
0.40
16
107
16
124
1.29
0.38
1.0
1.1
—
—
—
0
0
1338
13224
1.05
0.38
25.7
17.4
13.66
13.54
%
2.74
1328
13056
18
143
1.26
0.37
1.1
1.1
—
—
—
0
0
18
144
1.25
0.35
1.1
1.1
—
—
—
0
0
6
43
1.40
0.35
3.0
3.2
—
—
—
0
0
29
340
0.85
0.34
1.4
1.5
—
—
—
0
0
39
340
1.15
0.33
1.1
1.1
16.69
18.19
au/ml
—
7
88
15
118
1.27
0.33
1.2
1.1
1.05
1.04
ratio
0.25
15
97
21
253
0.83
0.33
2.7
2.4
—
—
—
0
0
6
86
0.70
0.33
1.8
1.4
128.50
128.72
nmol/l
—
6
86
30
347
0.86
0.31
1.0
1.1
0.11
1.18
u/ml
—
7
149
37
421
0.88
0.30
1.1
1.1
1.60
2.19
u/ml
0.34
13
222
22
184
1.20
0.30
2.4
1.5
—
—
—
0
0
7
57
1.23
0.29
4.1
2.2
0.00
0.00
estimate
—
7
57
7
57
1.23
0.29
2.3
2.4
150.00
161.49
nmol/l
—
7
51
39
345
1.13
0.28
1.1
1.1
—
—
—
0
0
8
62
1.29
0.28
3.0
1.6
—
—
—
0
0
24
279
0.86
0.27
1.0
1.1
0.60
3.91
u/ml
—
6
111
39
347
1.13
0.27
1.1
1.1
—
—
—
0
0
5
72
0.69
0.26
2.6
2.2
1.26
2.65
ug/l
—
5
62
5
74
0.67
0.26
2.8
2.2
0.88
3.43
ug/l
—
5
68
9
76
1.19
0.24
1.4
2.1
9.08
8.53
mmol/l
—
9
76
21
180
1.17
0.23
1.6
1.4
281.63
276.00
mosm/kgh2o
0.40
16
139
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
3.8
2.2
—
—
—
0
0
19
162
1.17
0.23
1.3
1.1
—
—
—
0
0
5
40
1.25
0.22
1.4
1.2
—
—
—
0
0
39
430
0.90
0.21
1.4
1.5
57.12
61.48
ug/l
0.27
30
353
5
42
1.19
0.21
1.8
1.7
0.36
0.47
e9/l
—
5
42
0
11
0.00
0.21
0.0
1.2
—
4353.80
—
0
5
0
11
0.00
0.21
0.0
1.8
—
359.27
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
27
304
0.89
0.21
1.1
1.1
0.92
3.01
u/ml
—
10
138
0
12
0.00
0.21
0.0
1.9
—
0.01
—
0
7
0
12
0.00
0.21
0.0
2.3
—
0.53
—
0
12
32
356
0.90
0.21
1.1
1.1
7.49
3.34
u/ml
0.43
11
179
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.00
—
0
7
6
50
1.20
0.19
1.3
1.1
—
—
—
0
0
1317
13259
0.97
0.19
26.9
18.2
330.66
330.78
g/l
0.19
1309
13198
33
300
1.10
0.17
8.7
2.3
0.76
0.89
nmol/l
0.86
28
255
7
61
1.15
0.17
1.7
2.2
7.27
9.50
mg/l
—
7
52
11
131
0.84
0.17
1.1
1.2
—
—
—
0
0
32
292
1.10
0.16
1.1
1.2
—
—
—
0
0
14
120
1.17
0.16
1.1
1.0
—
—
—
0
0
17
149
1.14
0.15
1.3
1.1
—
—
—
0
0
8
99
0.81
0.13
1.0
1.1
1447.63
1644.43
miu/ml
—
8
99
70
672
1.04
0.10
1.3
1.3
—
—
—
0
0
11
96
1.15
0.10
1.0
1.1
—
36.18
—
0
11
5
48
1.04
0.09
1.0
1.2
7.41
7.40
ph
—
5
32
15
165
0.91
0.09
1.1
1.3
0.19
0.60
u/ml
—
9
81
16
146
1.10
0.08
1.2
1.2
—
—
—
0
0
5
64
0.78
0.08
2.6
2.3
41.24
51.22
umol/l
—
5
53
77
749
1.03
0.06
1.1
1.1
—
—
—
0
0
13
119
1.09
0.06
1.7
2.0
17.38
19.11
nmol/l
0.28
13
114
18
168
1.07
0.06
1.3
1.1
—
—
—
0
0
11
101
1.09
0.04
14.4
13.2
0.72
0.65
mmol/l
0.25
11
89
10
92
1.09
0.03
1.5
1.2
13.80
9.53
mm/h
—
10
92
26
251
1.04
0.02
1.0
1.1
—
—
—
0
0
29
299
0.97
0.02
4.3
3.7
21.21
21.64
mg/l
0.03
19
200
26
252
1.03
0.02
1.0
1.1
80.67
2357.42
iu/ml
—
6
55
23
223
1.03
0.01
1.7
1.7
3.14
4.85
ug/l
0.51
16
189
26
266
0.98
0.00
2.9
2.5
8.32
7.42
mmol/l
0.92
26
256
32
325
0.98
0.00
2.7
2.4
1.54
1.52
mmol/l
0.05
32
314
20
198
1.01
0.00
5.2
5.5
15.42
93.18
u/ml
—
9
65
17
172
0.99
0.00
1.3
1.2
108.41
115.19
pmol/l
0.30
17
172
123
1231
1.00
0.00
6.0
3.4
1.23
1.23
mmol/l
0.69
109
1065
0
9
0.00
0.00
0.0
1.9
—
69.38
—
0
9
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
386.44
—
0
9
0
9
0.00
0.00
0.0
1.0
—
11.19
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
72.60
—
0
5
6
66
0.91
-0.00
2.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
286.60
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
153.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.7
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
159.00
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
35.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
9.74
—
0
7
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_VULVAL_DYSPLASIA_ALL and mortality.

Females

Parameter HR [95% CI] p-value
N14_VULVAL_DYSPLASIA_ALL 1.189 [1.04, 1.36] 0.011
Birth year 0.997 [0.99, 1.01] 0.487

During the follow-up period (1.1.1998 — 31.12.2019), 561 out of 4102 females with N14_VULVAL_DYSPLASIA_ALL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VULVAL_DYSPLASIA_ALL.

N-year risk Females Males
1 0.119% No data
5 0.789% No data
10 1.98% No data
15 3.774% No data
20 6.424% No data

Relationships between endpoints

Index endpoint: N14_VULVAL_DYSPLASIA_ALL – All dysplastic lesions of the vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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