This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Carcinoma in situ of colon
CD2_INSITU_COLON
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditions
|
549830 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
1162 |
4. Check minimum number of eventsNone |
1162 |
5. Include endpointsNone |
1162 |
6. Filter based on genotype QC (FinnGen only) |
1063 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D01
- Name in latin
- Carcinoma in situ ani
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of colon
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of other and unspecified digestive organs
- In situ neoplasms
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1063 | 468 | 595 |
| Unadjusted period prevalence (%) | 0.23 | 0.17 | 0.27 |
| Median age at first event (years) | 70.13 | 69.89 | 70.33 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1096
- Matched controls
- 10960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
12.2
315.9
388
473
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
14.6
304.6
312
290
K63.5
ICD-10 Finland
Polyp of colon
20.4
277.2
226
138
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
19.9
260.7
214
132
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
11.0
251.4
315
387
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
14.1
237.9
240
214
UJF32
NOMESCO Finland
Coloscopy
5.3
167.9
640
2278
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
11.2
149.9
170
177
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
16.4
126.3
110
74
C187, 8148, 2
ICD-O-3
676.8
124.9
121
*
8263/2-C18.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of colon, NOS
651.6
120.6
117
*
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
12.4
116.1
120
108
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
16.6
115.8
100
66
C189, 8211, 2
ICD-O-3
403.3
111.5
110
*
C187, 8211, 2
ICD-O-3
+∞
109.2
103
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
5.4
104.5
244
554
JFA15, ,
SPAT
21.9
96.0
72
35
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
10.7
90.3
102
104
UJF32, ,
SPAT
7.3
87.3
137
210
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
6.4
85.4
153
269
8263/2-C18.7
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of sigmoid colon
398.9
75.7
75
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.2
68.1
390
1624
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
8.0
67.9
96
130
8263/2-C18.0
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of cecum
353.0
67.3
67
*
C189, 8148, 2
ICD-O-3
+∞
66.3
63
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
8.3
59.8
81
104
UJF30
NOMESCO Finland
Ileoscopy through colon
3.6
59.3
231
752
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
23.5
59.2
43
19
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
9.5
52.9
64
71
C180, 8148, 2
ICD-O-3
521.1
50.8
50
*
WX402
NOMESCO Finland
General anaesthesia
2.7
48.8
366
1714
C180, 8211, 2
ICD-O-3
466.4
45.6
45
*
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
9.8
42.7
50
53
C189, 8213, 2
ICD-O-3
390.5
38.3
38
*
Z12.1
ICD-10 Finland
Special screening examination for neoplasm of intestinal tract
7.0
35.5
55
82
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.7
34.1
114
330
C182, 8148, 2
ICD-O-3
+∞
33.5
32
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
33.0
114
337
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
9.0
28.2
35
40
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
27.0
197
882
B01AB05
ATC
enoxaparin; parenteral
2.0
26.8
441
2742
WX600
NOMESCO Finland
Single shot through catheter
8.2
26.1
35
44
8263/2-C18.2
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of ascending colon
255.7
24.8
25
*
8211/2-C18.2
ICD-O-3
Tubular adenocarcinoma in situ of ascending colon
+∞
24.0
23
*
JN4AD
NOMESCO Finland
Body CT examination
2.3
24.0
208
1003
UJF30, ,
SPAT
7.9
23.9
33
43
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.8
23.1
130
511
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.9
23.0
114
418
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
22.6
202
985
C182, 8213, 2
ICD-O-3
+∞
21.9
21
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
21.4
174
814
C20
ICD-10 Finland
Malignant neoplasm of rectum
8.6
21.1
27
32
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
24.8
20.9
29
12
R4110
NOMESCO Finland
Physiotherapy
1.9
19.9
366
2310
C184, 8211, 2
ICD-O-3
+∞
19.8
19
*
D01.0
ICD-10 Finland
Carcinoma in situ: Colon
+∞
19.8
19
*
C187, 8213, 2
ICD-O-3
+∞
18.8
18
*
C181, 8480, 2
ICD-O-3
+∞
18.8
18
*
K92.1
ICD-10 Finland
Melaena
2.8
18.2
94
352
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
17.9
297
1803
JFA42
NOMESCO Finland
Endoscopic injection in colon
18.4
17.8
27
15
C186, 8211, 2
ICD-O-3
+∞
17.8
17
*
JFF23
NOMESCO Finland
Transversostomy
6.4
17.6
29
46
C184, 8148, 2
ICD-O-3
182.8
17.6
18
*
JG1BG
NOMESCO Finland
MRI of rectum
7.2
17.4
26
37
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
50.9
17.0
20
*
Z71.8
ICD-10 Finland
Other specified counselling
1.8
16.6
384
2569
B01AB10
ATC
tinzaparin; parenteral
2.2
16.6
164
827
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.1
16.0
68
228
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
14.8
15.9
26
18
C184, 8213, 2
ICD-O-3
+∞
15.7
15
*
C186, 8148, 2
ICD-O-3
162.2
15.5
16
*
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
7.1
15.3
23
33
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
10.6
14.3
27
26
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
5.0
14.1
30
61
8140/2-C18.7
ICD-O-3
Adenocarcinoma in situ, NOS, of sigmoid colon
+∞
13.6
13
*
C188, 8211, 2
ICD-O-3
+∞
12.5
12
*
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
10.2
12.5
24
24
WF001
NOMESCO Finland
Preoperative radiotherapy
5.7
12.5
23
41
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
11.9
247
1579
UJD10, ,
SPAT
3.4
11.9
43
131
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.0
11.9
52
178
Z3231
NOMESCO Finland
Registered nurse
1.6
11.7
310
2117
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
4.4
11.5
29
68
C180, 8213, 2
ICD-O-3
+∞
11.5
11
*
A98
ICPC
Health maint/preventive medicine
3.6
11.5
1068
10017
WZC30
NOMESCO Finland
Teaching
1.7
10.9
215
1354
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
5.3
10.6
21
40
C08CA01
ATC
amlodipine; oral
1.5
10.3
485
3754
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
19.0
10.3
15
8
WX704
NOMESCO Finland
Intubation
2.1
10.1
98
488
Z2221
NOMESCO Finland
Medical doctor
1.6
9.9
282
1948
TJF80
NOMESCO Finland
Ostomy education
4.7
9.6
22
48
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
9.3
229
1525
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
10.1
9.0
17
17
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.9
988
9094
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.9
348
2571
JFF10
NOMESCO Finland
Loop enterostomy
8.0
8.9
19
24
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
8.8
207
1361
JEA01
NOMESCO Finland
Laparoscopic appendectomy
2.9
8.7
40
141
B80
ICPC
Iron deficiency anaemia
3.2
8.7
33
104
JFB51
NOMESCO Finland
Other laparoscopic resection of colon
27.7
8.5
11
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
8.4
308
2238
8263/2-C18.4
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of transverse colon
90.7
8.4
9
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
8.3
143
863
D75
ICPC
Malignant neoplasm colon/rectum
4.6
8.1
19
42
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.1
399
3079
A02BC02
ATC
pantoprazole; systemic
1.5
8.0
766
6686
L01BC06
ATC
capecitabine; oral
2.3
8.0
58
257
WF002
NOMESCO Finland
Radical radiotherapy
2.0
7.8
82
421
D16
ICPC
Rectal bleeding
2.8
7.8
37
133
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
7.7
93
502
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
8.1
7.6
16
20
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
8.1
7.6
16
20
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.6
7.6
44
176
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.6
567
4707
T90
ICPC
Diabetes non-insulin dependent
1.5
7.5
306
2266
JG1CG
NOMESCO Finland
Extensive MRI of rectum
6.5
7.4
18
28
B82
ICPC
Anaemia other/unspecified
2.6
7.4
42
166
D12.1
ICD-10 Finland
Benign neoplasm: Appendix
10.9
7.3
13
12
8263/2-C18.6
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of descending colon
+∞
7.3
7
*
8261/2-C18.7
ICD-O-3
Adenocarcinoma in situ in villous adenoma of sigmoid colon
+∞
7.3
7
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.3
735
6415
207
Kela drug reimbursment
Chronic arrhythmias
1.6
7.3
204
1394
A10AE04
ATC
insulin glargine; parenteral
1.8
7.2
117
693
S18
ICPC
Laceration/cut
1.4
7.2
544
4510
K64.8
ICD-10 Finland
Other specified haemorrhoids
4.2
7.0
18
43
U07
ICPC
Urine symptom/complaint other
1.8
7.0
96
541
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
7.0
291
2161
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
6.9
382
2989
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
13.9
6.9
11
8
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
3.5
6.9
23
67
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
6.8
85
464
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.4
6.8
44
186
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
16.8
6.7
10
6
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
6.7
194
1334
D12
ICD-10 Finland
Benign neoplasm of colon, rectum, anus and anal canal
7.9
6.6
14
18
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
6.5
99
576
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
7.4
6.4
14
19
D18
ICPC
Change in faeces/bowel movements
2.6
6.4
36
142
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
6.6
6.3
15
23
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
18.1
6.3
9
5
8263/2-C18.8
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of overlapping lesion of colon
+∞
6.3
6
*
K64.0
ICD-10 Finland
First degree haemorrhoids
2.6
6.3
34
132
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.8
6.3
30
109
R03BB04
ATC
tiotropium bromide; inhalant
1.7
6.2
120
746
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
7.7
6.1
13
17
JFB30
NOMESCO Finland
Right hemicolectomy
3.2
6.0
23
73
S29
ICPC
Skin symptom/complaint other
1.5
6.0
213
1527
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
461
1273
5.52
163.87
4.3
4.5
6.32
22.95
ug/l
1.65
375
1061
387
1793
2.79
53.47
3.2
2.6
2.38
2.28
g/l
2.62
370
1667
367
1677
2.79
51.82
3.2
2.6
19.19
22.58
%
4.60
350
1567
396
1915
2.67
49.63
3.3
2.7
11.42
12.70
umol/l
2.95
380
1789
745
4886
2.64
48.64
3.7
2.9
—
—
estimate
—
0
0
741
4898
2.58
46.71
6.8
5.4
35.39
35.20
g/l
0.46
716
4604
475
2665
2.38
41.67
3.3
2.5
—
—
—
0
0
490
2813
2.34
40.46
3.0
2.3
2.96
2.91
mg/l
0.15
443
2420
668
4418
2.31
38.82
4.1
3.0
117.06
155.06
ug/l
4.66
629
4082
196
748
2.97
37.54
11.9
10.4
23.91
24.34
mmol/l
1.23
196
741
233
1012
2.65
34.70
2.6
2.5
47.03
41.57
u/l
0.21
194
850
789
5736
2.34
34.68
9.0
7.1
12.62
11.95
umol/l
0.38
759
5495
284
1421
2.35
30.81
10.0
8.4
0.20
0.93
mmol/l
2.60
250
1186
191
796
2.69
30.61
12.6
10.5
0.54
0.64
%
3.49
191
789
284
1441
2.31
29.69
10.3
8.4
5.17
5.12
kpa
0.47
279
1395
284
1441
2.31
29.69
10.3
8.4
12.78
12.08
kpa
1.58
278
1396
192
831
2.59
28.38
12.6
10.1
1.12
1.31
%
2.86
192
823
190
832
2.55
27.35
12.9
10.3
94.25
93.86
%
0.39
190
826
963
7950
2.74
27.35
12.0
8.9
83.20
80.46
u/l
0.81
937
7550
259
1307
2.29
27.15
10.6
8.7
95.52
95.46
%
0.04
253
1266
238
1159
2.35
27.12
2.8
2.3
0.22
0.21
g/l
1.99
223
1088
133
489
2.96
26.83
3.8
3.7
1040.49
3121.83
u/ml
0.44
111
418
239
1219
2.23
24.13
3.0
3.0
7.75
8.13
umol/l
0.12
213
1101
336
1962
2.03
23.75
3.5
3.0
0.94
1.09
e6/l
0.34
163
1074
708
5324
1.93
23.18
20.0
16.2
1.33
1.27
inr
1.66
575
4460
529
3628
1.89
22.98
3.9
3.5
147.21
77.98
e6/l
0.28
375
2813
762
5884
1.97
22.91
12.5
10.1
4.22
4.18
e9/l
0.19
623
5099
309
1800
2.00
21.68
3.7
3.2
1.24
1.94
e6/l
1.21
134
911
465
3124
1.85
21.00
3.7
3.4
0.89
0.46
e6/l
0.45
318
2320
803
6395
1.96
20.96
8.1
5.5
6.97
6.78
mmol/l
2.06
784
6150
717
5555
1.84
19.76
10.7
7.7
1.20
1.21
mmol/l
5.22
657
4807
1052
9488
3.71
18.32
26.6
18.2
30.62
26.30
mg/l
4.23
963
7972
657
5020
1.77
18.30
10.2
7.0
1.20
1.21
mmol/l
3.81
626
4644
204
1095
2.06
17.58
2.8
2.9
72.29
69.43
e9/l
0.46
136
821
470
3297
1.75
17.42
1.9
1.7
19.93
20.20
nmol/l
0.15
421
2761
1041
9393
3.16
16.86
27.9
17.8
75.53
77.06
ml/min/173m2
1.64
974
8811
633
4886
1.70
16.04
2.5
2.2
94.61
95.41
pmol/l
0.15
362
2628
880
7495
1.88
15.35
5.0
4.5
15.26
13.07
mm/h
3.28
835
6975
322
2087
1.77
15.33
1.2
1.3
2.90
1.40
u/ml
0.40
69
563
477
3459
1.67
14.97
4.6
3.4
38.96
33.61
u/l
0.33
452
3259
232
1379
1.87
14.62
4.2
4.5
236.00
250.77
u/l
0.87
227
1315
118
553
2.27
14.23
1.9
1.8
1.56
1.59
g/l
0.16
112
484
292
1884
1.75
13.92
1.6
1.6
2.66
2.67
g/l
0.01
143
1129
585
4540
1.62
13.53
16.8
12.7
0.00
0.00
e9/l
0.92
458
3739
193
1115
1.89
13.18
2.1
2.4
193.80
149.83
ug/g
0.87
159
905
1085
10247
6.86
12.36
42.1
27.7
243.94
243.21
e9/l
0.13
1063
10040
1085
10249
6.84
12.31
42.1
27.7
7.04
6.76
e9/l
2.07
1056
10003
1085
10249
6.84
12.31
42.1
27.7
4.38
4.47
e12/l
6.75
1057
10002
385
2752
1.62
12.13
3.4
3.1
0.27
0.03
0.60
11
62
463
3462
1.58
12.05
3.6
2.7
60.86
85.22
u/l
0.53
433
3211
661
5376
1.58
11.83
4.5
4.0
0.00
0.00
estimate
-0.00
125
1165
666
5441
1.57
11.56
4.6
4.0
0.00
2.83
estimate
0.81
128
1194
783
6646
1.62
11.53
5.7
4.8
265.20
1806.10
e6/l
1.57
15
115
289
1950
1.65
11.35
3.8
3.5
0.80
0.82
mmol/l
1.88
271
1840
1070
10059
3.69
11.19
17.9
13.4
26.58
26.33
u/l
0.17
1060
9773
193
1183
1.77
10.73
5.6
3.5
1.42
1.98
mmol/l
1.41
175
1018
665
5480
1.54
10.71
4.7
4.0
0.03
0.29
estimate
0.47
118
1106
100
505
2.08
9.97
1.8
2.5
3.71
3.75
g/l
0.08
95
460
477
3703
1.51
9.88
3.5
3.2
1363.60
1317.34
ng/l
0.11
429
3224
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
86
412
2.18
9.82
2.6
2.5
0.23
0.36
iu/ml
3.51
35
217
89
437
2.13
9.55
1.7
2.6
10.07
10.81
g/l
0.76
84
390
134
762
1.86
9.49
2.0
1.7
—
—
—
0
0
504
3991
1.49
9.29
4.5
4.2
8.49
8.31
mg/mmol
0.04
349
2528
215
1414
1.65
9.12
2.1
1.9
—
—
—
0
0
501
3974
1.48
9.09
3.8
3.5
7.59
7.58
mmol/l
0.01
444
3343
472
3708
1.48
8.95
4.9
3.8
2.36
2.35
mmol/l
0.65
434
3367
744
6445
1.48
8.20
4.4
3.5
72.86
56.46
u/l
2.79
706
6015
87
449
2.02
8.19
2.2
2.7
0.51
1.39
g/l
1.45
78
386
76
373
2.11
8.18
1.7
2.5
0.00
0.00
g/l
-0.00
70
323
137
822
1.76
8.11
1.7
1.7
—
—
—
0
0
77
383
2.09
8.01
1.8
2.5
0.00
0.03
g/l
0.97
71
343
220
1505
1.58
7.85
2.1
1.9
—
—
—
0
0
55
242
2.34
7.72
1.4
1.2
—
—
—
0
0
1035
9748
2.11
7.64
6.8
6.5
2.50
2.62
mmol/l
4.52
976
9006
301
2218
1.49
7.60
4.1
3.2
2.47
2.46
mmol/l
1.38
268
2009
1017
9536
1.92
7.37
5.4
5.5
1.42
1.44
mmol/l
0.84
959
8782
160
1033
1.64
7.21
2.4
3.0
65.82
66.42
g/l
0.50
152
954
851
7647
1.50
7.21
37.4
23.7
330.24
332.14
g/l
7.07
851
7611
603
5097
1.41
7.06
2.5
2.4
—
—
—
0
0
1020
9593
1.91
7.02
5.6
5.6
4.40
4.53
mmol/l
4.08
974
8905
1011
9491
1.84
6.87
6.2
5.7
6.28
6.06
mmol/l
5.15
960
8675
958
8881
1.63
6.60
6.0
5.3
2.04
2.00
mu/l
0.19
905
8116
999
9364
1.76
6.57
8.4
7.1
41.08
40.04
mmol/mol
3.12
953
8746
284
2149
1.43
6.06
4.4
4.3
593.95
416.44
ng/l
0.38
251
1783
264
1975
1.44
5.98
2.2
2.0
—
—
—
0
0
328
2557
1.40
5.89
2.8
2.7
4.11
5.00
e6/l
0.61
292
2338
540
4580
1.35
5.68
2.6
2.4
76.67
78.71
nmol/l
1.01
488
4088
370
2965
1.37
5.58
3.4
2.9
371.62
353.76
umol/l
2.47
330
2582
62
328
1.94
5.51
1.3
1.4
206.22
268.37
ug/g
1.69
36
205
213
1573
1.44
5.11
8.3
6.1
1.02
1.03
mmol/l
0.20
201
1459
127
851
1.56
4.89
1.6
1.5
—
—
—
0
0
289
2273
1.37
4.78
1.8
1.7
1.69
1.34
mg/l
0.45
247
1805
971
9165
1.52
4.66
4.6
4.7
1.36
1.31
mmol/l
1.26
907
8375
15
35
4.33
4.64
3.3
3.2
10.37
9.93
kpa
0.16
15
35
15
35
4.33
4.64
3.3
3.2
4.97
5.00
kpa
0.03
15
35
24
92
2.64
4.58
1.5
1.4
—
—
—
0
0
152
1085
1.47
4.34
2.1
1.8
1.71
1.59
%
0.68
133
911
74
453
1.68
4.13
2.2
2.8
—
—
—
0
0
48
270
1.81
3.62
1.7
1.5
—
—
—
0
0
19
75
2.56
3.47
1.5
3.3
133.84
93.89
nmol/l
0.50
19
75
14
47
3.00
3.42
1.1
1.1
—
—
—
0
0
45
255
1.80
3.34
3.0
3.4
0.77
0.83
nmol/l
0.44
36
213
39
212
1.87
3.30
1.2
1.3
—
—
—
0
0
39
212
1.87
3.30
1.2
1.3
—
—
—
0
0
54
328
1.68
3.16
1.6
1.6
24.55
18.02
u/ml
0.23
11
61
15
55
2.75
3.16
1.0
1.1
—
—
—
0
0
488
4305
1.24
3.09
4.9
4.2
27.32
59.65
ng/l
1.59
381
3343
88
605
1.49
3.07
1.6
1.5
—
—
—
0
0
66
429
1.57
2.97
2.3
1.7
0.32
0.36
mg/l
0.25
42
207
63
405
1.59
2.97
3.8
3.7
24.44
3.42
ratio
0.44
35
231
67
441
1.55
2.87
3.9
4.0
58.53
77.30
mg/l
0.26
62
377
67
442
1.55
2.84
3.8
4.0
138.59
63.67
mg/l
0.43
62
376
70
467
1.53
2.83
2.1
2.0
39.83
39.16
u/l
0.10
61
414
403
3509
1.23
2.82
2.3
2.3
215.45
223.30
u/l
0.07
378
3342
25
124
2.04
2.77
1.6
1.3
0.14
0.19
nmol/l
3.46
19
97
45
271
1.69
2.75
1.8
1.6
—
—
—
0
0
117
868
1.39
2.74
5.6
3.7
114.06
90.57
ng/l
1.56
104
751
50
311
1.64
2.71
1.7
1.6
10596.71
15972.31
e6/l
0.55
34
222
48
298
1.64
2.63
1.4
1.6
—
—
—
0
0
790
7408
1.24
2.57
4.8
4.2
15.16
14.98
pmol/l
1.19
741
6735
14
57
2.47
2.45
1.0
1.3
—
—
—
0
0
23
117
1.99
2.41
1.4
1.3
800914.53
188709.62
e6/l
0.79
15
80
47
303
1.58
2.25
2.1
1.6
—
—
—
0
0
13
54
2.42
2.20
1.7
2.9
648.08
897.09
u/ml
0.64
13
54
38
235
1.64
2.16
1.5
1.9
3.71
28.81
iu/l
0.51
16
95
14
61
2.31
2.15
2.7
1.4
—
—
—
0
0
14
61
2.31
2.15
2.7
1.4
—
—
—
0
0
9
30
3.02
2.15
2.2
3.3
3.67
5.63
ug/l
—
9
30
53
358
1.50
2.08
1.3
1.3
—
—
—
0
0
24
133
1.82
2.00
1.7
1.2
8.38
4.56
u/ml
—
8
43
117
918
1.31
1.95
5.1
4.3
1.22
1.23
mmol/l
0.18
100
798
111
865
1.32
1.94
3.2
2.8
11.20
10.90
g/l
0.27
104
800
405
3646
1.18
1.82
5.1
4.7
21.23
21.31
%
0.04
203
1874
46
313
1.49
1.78
1.5
1.4
—
—
—
0
0
23
132
1.76
1.74
1.4
1.4
88865.56
85506.83
e6/l
—
9
71
23
132
1.76
1.74
3.9
3.3
—
—
—
0
0
111
1378
0.78
1.67
5.2
5.2
32.69
32.13
%
0.19
77
912
46
318
1.47
1.67
1.5
1.6
0.00
0.08
iu/ml
—
6
49
315
2801
1.17
1.62
4.3
3.6
0.12
0.05
estimate
0.28
100
921
490
4512
1.16
1.60
6.0
5.8
2.90
2.70
ug/l
0.10
443
4071
35
231
1.53
1.58
6.4
6.4
280.50
338.13
iu/ml
—
6
30
477
4387
1.15
1.57
2.0
2.0
1.41
1.34
mmol/l
0.86
414
3607
43
298
1.46
1.55
2.2
2.3
124.13
128.57
g/l
0.46
32
238
56
408
1.39
1.55
1.8
1.6
7.40
7.44
iu/ml
0.00
11
95
46
325
1.43
1.51
1.3
1.4
—
—
—
0
0
22
132
1.68
1.46
1.9
1.2
4.60
6.02
u/ml
—
10
58
15
80
1.89
1.45
6.7
5.1
34.73
28.17
u/ml
—
6
23
25
156
1.62
1.44
1.4
1.4
1032.83
1766.73
e6/l
0.98
12
104
439
4035
1.15
1.43
4.8
4.0
4.84
0.03
estimate
0.50
104
964
18
103
1.76
1.41
1.4
1.4
25.06
28.48
%
0.15
12
66
17
97
1.76
1.35
4.2
3.2
10.00
11.77
index
—
10
61
39
274
1.44
1.34
3.6
3.5
42.65
1169.23
u/ml
0.69
32
258
19
113
1.69
1.32
2.6
2.7
—
—
—
0
0
15
83
1.82
1.31
2.5
2.7
9.65
8.09
mmol/l
0.39
15
83
21
129
1.64
1.30
1.4
1.1
—
—
—
0
0
39
276
1.43
1.30
1.7
1.6
—
—
—
0
0
25
161
1.57
1.29
1.1
1.1
325.98
86.66
iu/ml
—
6
29
109
900
1.23
1.26
2.6
3.2
182.15
210.85
ng/l
0.35
102
834
24
155
1.56
1.23
5.5
3.0
12.63
10.51
mmol/l
1.39
24
155
15
85
1.78
1.23
1.1
1.1
—
—
—
0
0
301
2722
1.15
1.22
3.6
3.4
0.77
0.76
ug/l
0.05
218
1848
45
332
1.37
1.20
1.8
1.6
—
—
—
0
0
13
71
1.84
1.19
1.2
1.3
—
—
—
0
0
138
1180
1.19
1.14
4.1
3.5
—
—
—
0
0
39
284
1.39
1.14
1.3
1.2
—
—
—
0
0
53
406
1.32
1.13
1.1
1.1
—
—
—
0
0
213
1892
1.16
1.11
1.7
1.8
1177.87
1191.78
nmol/l
0.07
169
1444
30
210
1.44
1.09
1.3
1.2
—
456.67
—
0
6
12
66
1.83
1.09
3.2
1.7
—
—
—
0
0
39
290
1.36
1.02
4.6
3.2
3.14
2.00
index
0.50
14
159
13
76
1.72
0.99
1.1
1.1
—
—
—
0
0
13
76
1.72
0.99
1.1
1.1
—
—
—
0
0
5
23
2.18
0.98
1.2
1.3
0.29
0.41
ug/l
—
5
16
12
197
0.60
0.94
1.4
1.2
1.54
1.55
g/l
0.06
12
197
6
27
2.23
0.93
2.8
6.8
6.90
5.58
kpa
—
6
27
25
175
1.44
0.93
1.2
1.3
136.57
169.52
au/ml
—
7
45
33
244
1.36
0.91
1.8
1.5
—
—
—
0
0
13
78
1.67
0.91
1.2
1.1
107.08
99.71
pmol/l
0.23
13
78
13
79
1.65
0.88
1.1
1.1
—
—
—
0
0
13
79
1.65
0.88
1.1
1.1
—
—
—
0
0
30
402
0.74
0.87
1.4
1.6
—
—
—
0
0
19
128
1.49
0.86
1.5
1.8
—
—
—
0
0
12
72
1.67
0.85
2.8
1.9
1.00
2.22
u/field
—
6
41
16
104
1.55
0.85
1.3
1.1
—
—
—
0
0
20
137
1.47
0.84
1.5
1.6
58.15
62.20
%
0.16
13
88
24
171
1.41
0.83
1.3
1.1
—
—
—
0
0
41
319
1.30
0.83
1.9
1.8
—
—
—
0
0
43
337
1.29
0.83
4.2
4.1
3.92
3.94
mmol/l
0.08
43
331
8
46
1.74
0.82
1.0
1.1
—
—
—
0
0
129
1133
1.16
0.81
1.3
1.3
—
—
—
0
0
64
529
1.22
0.80
1.1
1.2
140.78
143.39
u/ml
0.02
21
192
10
58
1.73
0.79
6.2
3.8
—
—
—
0
0
113
985
1.16
0.79
2.1
2.3
11.12
13.32
nmol/l
2.33
93
877
6
33
1.82
0.79
1.0
1.0
—
—
—
0
0
7
38
1.85
0.73
1.3
1.1
117.86
281.21
iu/ml
—
7
38
29
220
1.33
0.72
1.9
1.9
—
—
—
0
0
71
601
1.19
0.71
1.5
1.3
352.94
241.44
u/ml
0.45
63
556
9
57
1.58
0.71
3.0
3.1
1.06
1.08
%
—
9
57
21
152
1.39
0.69
1.7
1.5
—
—
—
0
0
10
61
1.65
0.68
4.8
3.3
3.50
0.95
index
—
10
61
14
94
1.50
0.67
1.1
1.1
—
—
—
0
0
63
532
1.20
0.66
4.4
3.8
1.02
1.02
ratio
1.49
58
501
31
242
1.29
0.65
1.7
1.5
—
—
—
0
0
115
1283
0.88
0.60
9.8
7.6
—
—
—
0
0
17
122
1.40
0.60
1.6
1.8
—
—
—
0
0
246
2294
1.09
0.59
1.9
1.8
446.14
34113077.10
pmol/l
2.35
211
1882
0
23
0.00
0.58
0.0
2.4
—
8.84
—
0
13
255
2386
1.09
0.57
5.2
4.1
1.02
1.02
kg/l
0.07
194
1606
38
311
1.23
0.56
1.9
1.7
—
—
—
0
0
35
285
1.24
0.54
1.2
1.2
3.58
3.02
u/ml
—
6
41
22
169
1.31
0.53
1.9
1.7
—
—
—
0
0
329
3122
1.08
0.52
5.1
4.1
0.00
0.00
estimate
0.78
108
1074
14
100
1.41
0.52
1.3
1.3
29.93
11.78
u/l
0.55
14
90
13
92
1.42
0.50
1.3
1.4
12.23
13.76
u/l
0.44
13
86
33
399
0.82
0.49
2.0
1.8
—
—
—
0
0
36
429
0.83
0.47
2.2
2.0
—
—
—
0
0
108
981
1.11
0.46
3.5
2.3
347.53
381.60
nmol/l
1.03
101
914
25
307
0.81
0.44
1.6
1.8
11.71
5.09
mg/l
0.49
19
241
13
95
1.37
0.44
1.2
1.0
—
—
—
0
0
54
473
1.15
0.41
2.7
2.2
1331.15
465.97
ug/l
0.65
54
450
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
35
296
1.19
0.41
1.9
2.1
12.62
12.18
mg/l
0.11
35
277
0
17
0.00
0.40
0.0
1.1
—
1.17
—
0
17
31
368
0.84
0.40
1.4
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
2.0
—
0.63
—
0
12
15
115
1.31
0.39
1.1
1.1
6.06
1.76
u/ml
—
10
62
8
116
0.69
0.37
1.6
1.5
—
—
—
0
0
9
71
1.27
0.36
1.1
1.1
—
81.33
—
0
6
113
1046
1.09
0.35
2.4
2.4
7.86
7.69
ug/l
0.03
107
944
25
208
1.21
0.35
1.7
1.5
—
—
—
0
0
6
43
1.40
0.35
1.3
1.0
—
—
—
0
0
14
178
0.78
0.34
1.1
1.3
64.79
197.34
miu/ml
—
6
71
19
154
1.24
0.34
2.4
1.8
—
—
—
0
0
50
560
0.89
0.32
1.5
1.8
3.37
3.46
mmol/l
0.18
34
422
27
229
1.18
0.32
3.3
3.6
34.86
28.74
mg/l
0.33
21
159
12
92
1.31
0.32
2.2
1.6
—
—
—
0
0
7
53
1.32
0.31
1.1
1.6
38.90
40.18
g/l
—
7
53
177
1680
1.06
0.30
1.3
1.3
23.79
13.24
u/ml
0.61
55
629
191
1819
1.06
0.29
1.3
1.3
35.07
34.22
iu/ml
0.03
58
566
22
185
1.19
0.29
1.4
1.3
10.58
7.97
u/l
0.48
15
144
8
108
0.74
0.29
1.1
1.4
—
—
—
0
0
8
62
1.29
0.28
1.7
2.0
—
—
—
0
0
8
66
1.21
0.26
1.5
1.6
1.38
8.88
u/l
—
8
56
24
207
1.16
0.25
2.5
4.0
15.83
9.70
pmol/l
1.06
24
207
42
378
1.12
0.25
1.2
1.3
—
—
—
0
0
24
208
1.16
0.24
1.1
1.1
—
6.04
—
0
19
25
286
0.87
0.24
2.6
2.4
76.27
117.37
ug/min
0.46
15
168
5
38
1.32
0.23
1.2
2.7
33.62
228.46
ug/l
—
5
33
13
106
1.23
0.23
1.3
1.6
—
—
—
0
0
13
106
1.23
0.23
1.3
1.6
—
—
—
0
0
13
106
1.23
0.23
1.3
1.6
—
—
—
0
0
12
97
1.24
0.23
1.2
1.3
—
—
—
0
0
35
314
1.12
0.22
1.4
1.8
43.69
41.73
nmol/l
0.25
35
298
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
8.14
—
0
11
0
11
0.00
0.21
0.0
1.4
—
16.82
—
0
11
0
10
0.00
0.21
0.0
2.8
—
0.60
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
12
0.00
0.21
0.0
1.3
—
5422.57
—
0
7
0
12
0.00
0.21
0.0
3.9
—
—
—
0
0
5
43
1.16
0.21
1.0
1.0
1414.00
1433.16
miu/ml
—
5
43
0
13
0.00
0.21
0.0
1.1
—
16.39
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
14
117
1.20
0.20
2.5
1.6
29.15
36.50
ng/l
0.30
14
117
75
799
0.93
0.20
1.9
2.1
3.44
3.49
ratio
0.11
60
663
10
81
1.24
0.18
2.4
1.6
—
—
—
0
0
7
61
1.15
0.17
4.1
2.3
—
—
—
0
0
29
262
1.11
0.17
1.2
1.2
—
—
—
0
0
20
176
1.14
0.17
1.3
1.2
280.31
316.19
u/ml
0.26
13
94
10
82
1.22
0.17
2.4
1.6
—
—
—
0
0
73
690
1.06
0.17
3.8
3.6
1.65
1.97
mmol/l
0.33
56
532
17
194
0.87
0.16
1.4
1.5
—
—
—
0
0
29
263
1.11
0.16
1.2
1.1
—
—
—
0
0
8
72
1.11
0.16
1.0
1.3
—
51.43
—
0
7
20
179
1.12
0.14
1.1
1.1
—
1.07
—
0
6
9
109
0.82
0.13
1.1
1.2
7.16
7.53
mmol/l
—
9
93
99
958
1.04
0.10
1.3
1.4
—
—
—
0
0
5
44
1.14
0.10
1.4
2.2
0.59
0.61
mmol/l
—
5
44
5
48
1.04
0.09
1.0
1.5
—
—
—
0
0
88
907
0.97
0.09
2.9
3.0
64.67
61.51
ml/min/173m2
0.41
39
382
6
57
1.05
0.08
2.2
2.4
—
—
—
0
0
10
113
0.88
0.08
1.2
1.1
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
11
98
1.12
0.07
1.1
1.1
2.00
2.20
eliau/ml
—
5
33
6
74
0.81
0.07
1.3
1.4
—
—
—
0
0
6
74
0.81
0.07
1.3
1.4
—
—
—
0
0
8
74
1.08
0.07
1.5
1.8
108.27
109.78
ng/l
—
8
74
8
77
1.04
0.07
1.0
1.4
—
418.57
—
0
7
8
90
0.89
0.06
1.1
1.1
—
—
—
0
0
19
179
1.06
0.05
1.3
1.3
—
—
—
0
0
13
140
0.93
0.04
1.6
1.6
—
—
—
0
0
13
139
0.93
0.03
1.5
1.6
—
—
—
0
0
22
211
1.04
0.03
1.0
1.4
—
—
—
0
0
13
138
0.94
0.02
1.5
1.6
—
—
—
0
0
13
138
0.94
0.02
1.5
1.6
—
—
—
0
0
15
158
0.95
0.02
1.1
1.0
—
—
—
0
0
12
113
1.06
0.02
2.0
1.7
—
—
—
0
0
15
143
1.05
0.01
3.9
2.6
41.50
21.82
mg/l
—
8
58
25
244
1.03
0.00
1.3
1.3
—
—
—
0
0
14
142
0.99
0.00
1.6
1.6
—
—
—
0
0
14
142
0.99
0.00
1.6
1.6
—
—
—
0
0
24
238
1.01
0.00
1.7
1.3
7116.16
650.28
e6/l
0.44
19
178
13
131
0.99
0.00
1.1
1.4
—
—
—
0
0
10
103
0.97
0.00
1.2
1.1
—
—
—
0
0
10
103
0.97
0.00
2.6
1.7
—
—
—
0
0
16
163
0.98
0.00
1.5
1.3
17.61
32.80
iu/l
0.95
11
131
23
233
0.99
0.00
1.7
1.2
7.82
30.61
e6/l
0.76
17
166
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
2.33
—
0
6
5
58
0.86
0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
46.23
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.2
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
844.29
—
0
7
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
66
0.91
-0.00
1.3
1.4
151.83
155.04
pmol/l
—
6
66
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_COLON – Carcinoma in situ of colon
GWS hits: 1
This endpoint is excluded from FinRegistry analyses (omitted endpoint).