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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ of colon

CD2_INSITU_COLON

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

  • not C3_COLON
513404

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D01.0&
  • Hospital discharge: ICD-9 2303
  • Cause of death: ICD-10 D01.0&
  • Cause of death: ICD-9 2303
  • Cancer registry: Topography ICD-O-3 C18
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

678

4. Check minimum number of events

None

678

5. Include endpoints

None

678

6. Filter based on genotype QC (FinnGen only)

652

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D01
Name in latin
Carcinoma in situ ani

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 652 268 384
Unadjusted period prevalence (%) 0.14 0.10 0.18
Median age at first event (years) 71.21 71.04 71.33

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
678
Matched controls
6780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
14.9
187.9
190
173
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
19.4
176.4
148
96
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
15.3
161.7
156
130
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
27.5
160.0
113
49
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
10.3
155.3
208
279
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
10.0
138.6
186
248
UJF32
NOMESCO Finland
Coloscopy
6.2
123.0
415
1382
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
19.0
99.5
81
48
K63.5
ICD-10 Finland
Polyp of colon
14.7
94.8
89
69
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
6.5
89.4
174
341
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
11.1
89.1
101
105
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
13.2
82.2
82
70
C187, 8211, 2
ICD-O-3
+∞
82.0
77
*
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
12.3
67.6
70
63
C187, 8148, 2
ICD-O-3
+∞
64.6
61
*
8263/2-C18.9
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of colon, NOS
+∞
63.5
60
*
WX402
NOMESCO Finland
General anaesthesia
3.9
61.2
259
926
8263/2-C18.0
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of cecum
607.0
57.5
56
*
UJF32, ,
SPAT
8.4
55.4
76
100
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
6.4
50.9
91
160
C189, 8211, 2
ICD-O-3
275.2
50.8
51
*
8263/2-C18.7
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of sigmoid colon
524.7
50.1
49
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
8.4
47.5
65
85
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.7
47.1
96
191
B01AB05
ATC
enoxaparin; parenteral
3.1
46.5
344
1682
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
8.6
39.3
52
65
C180, 8211, 2
ICD-O-3
+∞
37.9
36
*
C189, 8148, 2
ICD-O-3
+∞
34.7
33
*
JFA15, ,
SPAT
44.7
34.4
42
10
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
8.4
33.6
45
57
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.9
33.3
220
976
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
9.8
33.0
39
42
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
9.4
32.7
40
45
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
4.2
32.6
96
257
C180, 8148, 2
ICD-O-3
315.8
30.0
30
*
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
9.9
30.0
35
37
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
28.4
144
547
UJF30
NOMESCO Finland
Ileoscopy through colon
3.3
27.9
121
419
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.6
25.2
63
148
C182, 8148, 2
ICD-O-3
+∞
25.2
24
*
L01BC06
ATC
capecitabine; oral
4.2
24.3
68
174
8263/2-C18.2
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of ascending colon
+∞
22.0
21
*
JN4AD
NOMESCO Finland
Body CT examination
2.8
22.0
126
508
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
19.2
21.9
33
18
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
8.0
21.8
30
39
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.9
21.7
68
189
8211/2-C18.2
ICD-O-3
Tubular adenocarcinoma in situ of ascending colon
+∞
19.9
19
*
D01.0
ICD-10 Finland
Carcinoma in situ: Colon
+∞
18.8
18
*
R4110
NOMESCO Finland
Physiotherapy
2.1
18.3
237
1364
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
20.0
18.3
27
14
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
6.5
18.1
30
48
B01AB10
ATC
tinzaparin; parenteral
2.7
17.6
106
436
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
17.5
113
481
C184, 8211, 2
ICD-O-3
+∞
16.7
16
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.9
16.2
82
307
WX600
NOMESCO Finland
Single shot through catheter
11.6
15.4
28
25
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
15.3
111
498
K92.1
ICD-10 Finland
Melaena
3.2
15.2
64
215
130
Kela drug reimbursment
Malignant tumour
2.5
14.1
101
450
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
54.5
13.9
16
*
C189, 8213, 2
ICD-O-3
+∞
13.6
13
*
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
15.4
13.2
21
14
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
12.8
241
1546
Z71.8
ICD-10 Finland
Other specified counselling
1.9
12.6
211
1301
C184, 8148, 2
ICD-O-3
+∞
12.5
12
*
C188, 8211, 2
ICD-O-3
+∞
12.5
12
*
8140/2-C18.7
ICD-O-3
Adenocarcinoma in situ, NOS, of sigmoid colon
+∞
12.5
12
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
12.1
184
1098
JFB30
NOMESCO Finland
Right hemicolectomy
5.4
11.6
23
44
C186, 8211, 2
ICD-O-3
+∞
11.5
11
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
10.8
11.3
21
20
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.7
11.2
36
102
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
8.3
11.2
24
30
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
8.8
11.1
23
27
C20
ICD-10 Finland
Malignant neoplasm of rectum
10.3
11.1
21
21
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
15.8
10.9
17
11
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.6
10.6
35
101
C187, 8213, 2
ICD-O-3
+∞
10.4
10
*
UJF30, ,
SPAT
9.3
10.1
20
22
Z3231
NOMESCO Finland
Registered nurse
1.8
9.9
203
1316
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
9.8
75
343
K64.0
ICD-10 Finland
First degree haemorrhoids
4.3
9.7
25
60
C08CA01
ATC
amlodipine; oral
1.7
9.6
310
2272
N02BE01
ATC
paracetamol; systemic, rectal
2.3
9.6
617
5502
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
17.8
9.4
14
8
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
12.6
9.4
16
13
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
10.2
9.1
17
17
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.5
9.0
59
251
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
7.0
8.9
21
31
WX704
NOMESCO Finland
Intubation
2.4
8.7
62
274
D50
ICD-10 Finland
Iron deficiency anaemia
4.3
8.7
22
52
A10AE04
ATC
insulin glargine; parenteral
2.1
8.5
85
434
8263/2-C18.4
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of transverse colon
91.2
8.4
9
*
A98
ICPC
Health maint/preventive medicine
3.3
8.3
654
6055
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
8.2
227
1585
UJD10, ,
SPAT
3.7
8.1
25
69
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
9.1
8.1
16
18
JFB43
NOMESCO Finland
Left hemicolectomy
10.2
8.1
15
15
A04AA02
ATC
granisetron; systemic, transdermal
2.3
7.9
61
280
WZC30
NOMESCO Finland
Teaching
1.8
7.9
124
738
B82
ICPC
Anaemia other/unspecified
3.1
7.7
31
102
JN4BD
NOMESCO Finland
Extensive body CT
1.9
7.6
95
524
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
7.5
454
3785
Z2221
NOMESCO Finland
Medical doctor
1.7
7.5
184
1240
A02BC02
ATC
pantoprazole; systemic
1.6
7.5
470
3954
JFF10
NOMESCO Finland
Loop enterostomy
9.5
7.3
14
15
JFA98, ,
SPAT
+∞
7.3
7
*
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
7.3
155
1005
S18
ICPC
Laceration/cut
1.6
7.3
335
2618
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
7.3
254
1865
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
3.6
7.0
23
66
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
6.9
53
243
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
6.8
193
1344
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.0
6.8
29
99
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
40.5
6.8
8
*
JFB51
NOMESCO Finland
Other laparoscopic resection of colon
22.8
6.7
9
*
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
6.5
6.7
16
25
WX110, ,
SPAT
2.5
6.7
42
176
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
6.7
146
953
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
8.8
6.6
13
15
8140/3-C18.0
ICD-O-3
Adenocarcinoma, NOS, of cecum
6.9
6.5
15
22
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.4
6.5
18
34
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
6.4
256
1926
JFF23
NOMESCO Finland
Transversostomy
5.3
6.4
18
35
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
3.5
6.3
21
61
D12
ICD-10 Finland
Benign neoplasm of colon, rectum, anus and anal canal
11.2
6.3
11
10
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
6.3
149
991
ZXE00
NOMESCO Finland
One hour or less
1.5
6.3
251
1886
8263/2-C18.8
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of overlapping lesion of colon
+∞
6.3
6
*
8140/2-C18.0
ICD-O-3
Adenocarcinoma in situ, NOS, of cecum
+∞
6.3
6
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.7
6.2
33
127
D75
ICPC
Malignant neoplasm colon/rectum
5.8
6.2
16
28
WF002
NOMESCO Finland
Radical radiotherapy
2.2
6.2
52
248
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
7.8
6.1
13
17
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.1
186
1313
JFA42
NOMESCO Finland
Endoscopic injection in colon
10.1
6.0
11
11
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
5.3
6.0
17
33
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
6.0
344
2774

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
478
691
21.06
307.65
1.9
1.3
—
—
—
0
0
363
734
9.49
195.48
4.8
4.4
6.96
31.32
ug/l
1.37
299
622
243
889
3.70
54.62
2.7
2.4
17.57
22.40
%
6.23
220
750
248
921
3.67
54.46
2.7
2.5
2.41
2.28
g/l
2.91
239
855
481
2710
3.67
53.47
6.5
5.1
34.87
34.98
g/l
0.17
464
2542
490
2799
3.71
53.15
3.5
2.7
—
—
—
0
0
254
991
3.50
51.16
2.8
2.5
10.88
12.56
umol/l
3.01
247
924
423
2281
3.27
48.86
2.5
2.2
—
—
—
0
0
327
1536
3.18
47.68
2.8
2.2
3.37
3.15
mg/l
0.47
284
1311
375
1930
3.11
46.15
3.3
2.5
—
—
—
0
0
412
2269
3.08
44.32
3.5
2.7
108.95
160.35
ug/l
5.52
384
2057
303
1497
2.85
38.32
3.0
2.4
—
—
—
0
0
127
373
3.96
38.21
10.8
10.8
—
—
—
0
0
136
438
3.63
35.63
12.8
9.4
0.60
0.67
%
1.66
136
432
135
439
3.59
34.80
12.7
9.3
1.18
1.39
%
2.35
135
433
133
438
3.53
33.55
13.2
9.6
94.72
93.83
%
1.14
133
433
102
283
4.07
33.01
3.3
3.7
1269.27
4914.15
u/ml
0.48
89
243
191
807
2.90
31.43
10.5
7.9
-0.01
1.18
mmol/l
4.14
166
653
164
644
3.04
30.74
2.5
2.2
0.22
0.21
g/l
1.91
151
603
146
538
3.18
30.53
13.2
9.0
—
—
—
0
0
483
3263
2.67
29.56
9.0
6.7
12.67
11.89
umol/l
0.32
465
3109
186
810
2.79
28.60
10.8
7.9
13.15
12.04
kpa
2.17
181
777
141
536
3.06
27.76
2.4
2.4
33.75
33.87
u/l
0.02
118
461
328
1941
2.34
25.59
3.3
3.3
226.52
96.40
e6/l
0.33
228
1526
592
4601
3.26
24.88
11.3
8.1
85.07
79.65
u/l
1.36
580
4321
294
1706
2.28
23.50
3.2
3.1
—
—
—
0
0
503
3647
2.47
23.49
8.0
5.1
7.09
6.81
mmol/l
2.13
491
3450
179
836
2.55
23.39
1.4
1.2
—
—
—
0
0
352
2202
2.24
23.38
4.0
3.8
108.40
91.43
e6/l
0.18
235
1624
301
1792
2.22
22.30
3.2
3.2
1.22
0.54
e6/l
0.47
208
1384
258
1473
2.21
20.90
1.3
1.3
—
—
—
0
0
211
1111
2.31
20.79
2.9
2.8
1.11
1.13
e6/l
0.02
103
666
440
3106
2.19
20.46
20.6
16.6
1.37
1.31
inr
0.60
129
903
199
1035
2.31
20.08
3.0
3.0
1.33
1.79
e6/l
0.48
90
599
163
777
2.45
20.06
2.6
2.6
1.89
1.82
%
0.34
148
704
301
1861
2.11
19.56
4.4
3.4
44.06
32.98
u/l
0.46
284
1764
203
1077
2.26
19.45
1.2
1.2
2.18
1.27
u/ml
0.61
37
293
149
698
2.45
18.95
3.3
2.8
7.94
9.05
umol/l
0.29
130
627
297
1860
2.06
18.33
5.6
4.4
—
—
—
0
0
128
573
2.52
17.87
2.1
2.2
234.13
146.44
ug/g
1.44
109
464
430
3097
2.06
17.80
10.2
7.2
1.19
1.21
mmol/l
5.91
378
2636
156
768
2.34
17.64
1.2
1.3
—
—
—
0
0
453
3350
2.06
17.11
12.3
9.6
4.23
4.16
e9/l
0.21
360
2955
400
2836
2.00
16.95
9.7
6.4
1.19
1.21
mmol/l
3.57
381
2575
185
993
2.19
16.91
1.6
1.5
2.54
2.76
g/l
0.49
78
591
649
5637
4.54
16.82
25.6
16.2
32.90
26.67
mg/l
4.82
607
4558
129
598
2.43
16.63
2.9
2.7
74.12
70.21
e9/l
0.48
92
474
93
369
2.76
16.49
1.2
1.2
—
—
—
0
0
365
2551
1.93
15.64
14.7
10.1
0.00
0.00
e9/l
0.56
280
2109
121
574
2.35
14.70
1.4
1.4
—
—
—
0
0
374
2714
1.84
13.48
7.8
6.2
—
—
—
0
0
276
1838
1.85
13.02
4.7
4.2
7.41
7.40
ph
1.10
56
366
390
2886
1.83
13.00
7.0
5.7
0.61
0.61
e9/l
0.18
308
2489
357
2577
1.81
12.87
2.4
2.1
90.96
94.78
pmol/l
0.88
205
1336
390
2897
1.82
12.73
7.0
5.7
0.04
0.04
e9/l
0.97
308
2507
490
3907
1.92
12.71
5.3
4.6
50.55
2865.68
e6/l
1.52
11
75
362
2632
1.81
12.67
7.1
5.9
0.64
0.66
%
0.28
340
2470
243
1569
1.86
12.56
1.8
1.6
19.70
20.44
nmol/l
0.36
214
1316
393
2940
1.80
12.38
7.3
5.8
2.07
1.97
e9/l
0.13
321
2591
524
4292
1.97
12.27
4.7
4.2
15.65
13.57
mm/h
1.91
493
3939
370
2728
1.78
12.16
7.3
6.2
8.89
8.90
%
0.01
348
2562
75
311
2.59
12.11
1.8
2.0
1.68
1.54
g/l
0.69
69
270
195
1186
1.90
12.06
3.7
3.3
2.47
2.46
mmol/l
0.79
169
1054
395
2973
1.79
12.06
7.2
6.0
0.18
0.20
e9/l
0.88
318
2611
367
2716
1.77
11.76
7.1
5.9
2.59
2.88
%
1.82
345
2547
171
1007
1.93
11.60
3.8
3.5
0.79
0.82
mmol/l
1.33
163
944
372
2774
1.76
11.51
7.5
6.1
24.91
26.82
%
2.33
349
2606
515
4229
1.91
11.49
4.9
4.2
—
—
—
0
0
367
2729
1.75
11.44
7.1
5.8
60.11
57.74
%
3.01
346
2569
290
2039
1.74
10.86
4.7
3.7
2.36
2.35
mmol/l
0.51
262
1789
658
6011
4.21
10.71
15.8
11.5
26.00
26.21
u/l
0.14
649
5780
61
245
2.64
10.49
1.8
2.9
9.90
10.71
g/l
0.76
55
216
279
1962
1.72
10.30
3.4
2.5
60.95
99.20
u/l
0.46
261
1825
667
6181
5.88
9.98
40.0
24.0
6.98
6.78
e9/l
0.79
640
5997
667
6181
5.88
9.98
41.4
24.1
38.45
39.98
%
7.26
638
5743
667
6181
5.88
9.98
39.9
24.0
240.11
240.85
e9/l
0.10
645
6022
371
2833
1.68
9.94
6.1
5.2
0.00
0.00
estimate
-0.00
79
546
667
6183
5.85
9.93
40.0
24.0
4.36
4.47
e12/l
5.30
642
5999
372
2846
1.68
9.87
4.5
3.9
0.00
0.00
estimate
0.50
84
588
310
2267
1.68
9.73
3.8
3.6
4.95
5.79
ph
—
9
139
371
2875
1.64
9.05
4.6
3.9
0.00
0.00
estimate
-0.00
76
530
282
2046
1.65
8.90
3.4
3.0
1250.68
1430.17
ng/l
0.39
256
1777
484
4027
1.71
8.83
5.4
4.4
—
—
—
0
0
52
212
2.57
8.69
1.8
2.9
36.68
37.25
g/l
0.26
47
184
262
1879
1.64
8.58
4.0
3.2
—
—
—
0
0
201
1357
1.68
8.26
3.3
3.8
—
—
—
0
0
636
5816
2.51
8.11
24.6
15.6
—
—
—
0
0
102
569
1.93
7.92
2.9
3.2
65.76
66.65
g/l
0.65
95
515
23
61
3.87
7.85
1.5
1.3
—
—
—
0
0
578
5129
1.86
7.61
5.0
4.6
2.06
1.99
mu/l
0.26
526
4598
618
5616
2.13
7.47
5.3
5.0
6.30
6.07
mmol/l
3.50
569
5054
89
484
1.97
7.44
2.6
2.8
—
—
—
0
0
66
321
2.17
7.43
2.5
2.5
—
—
—
0
0
157
1018
1.71
7.40
2.5
2.0
31.11
29.77
s
1.04
157
986
190
1298
1.64
7.34
3.2
2.9
547.52
553.46
mosm/kgh2o
0.14
153
1120
434
3593
1.58
7.29
4.2
3.3
79.27
56.91
u/l
2.26
409
3311
277
2076
1.57
7.24
3.9
3.8
8.13
8.87
mg/mmol
0.16
188
1314
195
1364
1.60
6.77
2.5
2.5
4.82
4.38
e6/l
0.15
172
1231
266
2002
1.54
6.69
3.3
3.2
7.92
7.65
mmol/l
0.41
231
1651
29
102
2.93
6.44
2.9
2.2
—
—
—
0
0
260
1960
1.53
6.43
3.2
3.3
254.23
230.51
mg/l
0.04
186
1293
21
61
3.52
6.33
1.1
1.1
—
—
—
0
0
201
1438
1.57
6.26
7.9
7.1
—
—
—
0
0
40
169
2.45
6.25
1.4
1.7
—
—
—
0
0
143
949
1.64
6.07
2.6
2.1
—
—
—
0
0
622
5751
1.99
5.83
5.5
5.4
2.48
2.65
mmol/l
4.56
572
5221
100
611
1.75
5.76
4.5
3.7
1.10
2.03
mmol/l
1.72
87
508
57
295
2.02
5.49
3.8
4.0
23.59
24.28
mmol/l
0.90
57
288
610
5631
1.83
5.36
4.6
4.8
4.34
4.52
mmol/l
4.06
571
5149
19
60
3.23
5.07
1.4
1.3
—
—
nmol/l
—
0
0
217
1642
1.47
5.01
1.6
1.7
1.44
1.35
mmol/l
0.63
182
1359
290
2320
1.44
4.99
2.2
2.3
76.25
78.59
nmol/l
0.75
258
2025
591
5433
1.68
4.93
7.4
6.3
42.31
40.64
mmol/mol
3.41
559
4983
605
5598
1.75
4.91
4.6
4.7
1.41
1.43
mmol/l
0.70
555
5075
172
1247
1.51
4.89
1.8
1.7
2.06
1.34
mg/l
0.64
142
999
59
324
1.90
4.81
3.2
2.4
1.10
1.17
%
0.31
59
324
85
522
1.72
4.80
5.0
3.8
1.22
1.23
mmol/l
0.10
73
460
98
626
1.66
4.79
1.4
1.6
—
—
—
0
0
83
516
1.69
4.49
1.5
1.6
—
—
—
0
0
33
152
2.23
4.31
4.0
3.5
16.38
1929.06
u/ml
0.65
26
145
106
710
1.58
4.27
1.3
1.3
813.91
514.90
titre
0.58
23
157
23
90
2.61
4.26
1.1
1.1
—
—
—
0
0
45
238
1.95
4.12
5.1
4.3
189.42
86.11
mg/l
0.34
38
193
122
851
1.53
4.11
6.1
5.8
0.99
1.03
mmol/l
1.02
116
784
16
52
3.13
4.10
3.6
3.2
33.39
34.06
mg/l
0.01
11
41
45
239
1.95
4.07
5.3
4.3
64.71
85.36
mg/l
0.15
38
197
300
2477
1.38
4.05
4.9
3.9
24.83
51.86
ng/l
1.40
234
1906
581
5407
1.52
3.60
4.0
4.3
1.38
1.31
mmol/l
1.35
530
4877
82
539
1.59
3.58
1.4
1.5
—
—
—
0
0
44
243
1.87
3.57
3.5
3.0
0.40
0.23
g/l
0.94
26
107
30
146
2.10
3.47
2.8
2.8
—
—
—
0
0
463
4154
1.36
3.41
3.9
3.7
15.15
14.99
pmol/l
0.60
420
3699
18
70
2.61
3.40
1.9
3.1
9.26
5.75
nmol/l
0.22
18
70
73
475
1.60
3.33
3.3
4.2
0.42
0.51
%
0.24
32
178
23
105
2.23
3.12
3.3
2.9
4.18
4.45
e9/l
0.34
23
105
496
4529
1.35
3.05
36.6
21.5
329.23
332.26
g/l
8.94
496
4504
14
51
2.78
3.00
2.2
1.6
10.21
10.60
%
0.11
14
51
54
336
1.66
2.96
1.4
1.4
—
—
—
0
0
33
178
1.90
2.92
1.2
1.5
230.49
272.66
ug/g
0.50
16
105
71
475
1.55
2.90
3.8
3.8
92.98
91.94
ng/l
0.03
64
412
11
33
3.37
2.82
1.7
4.0
161.55
114.24
nmol/l
0.33
11
33
77
529
1.51
2.80
3.6
4.2
0.68
0.94
%
0.79
36
211
27
138
2.00
2.79
2.9
3.8
—
—
—
0
0
23
111
2.11
2.76
3.7
3.2
57.43
58.59
%
0.16
23
111
58
375
1.60
2.75
2.3
1.8
1.16
1.53
g/l
0.74
51
340
28
147
1.94
2.69
2.0
2.2
124.33
129.55
g/l
0.45
21
109
15
61
2.49
2.63
1.2
1.3
—
—
—
0
0
50
316
1.63
2.61
2.7
2.7
—
—
—
0
0
53
340
1.61
2.60
1.3
1.3
—
—
—
0
0
25
128
1.99
2.58
3.2
2.5
—
—
—
0
0
12
44
2.76
2.56
2.4
3.0
—
—
—
0
0
5
7
7.19
2.55
2.0
3.4
122.80
87.73
pmol/l
—
5
7
68
467
1.51
2.49
3.6
4.4
0.00
0.69
%
0.63
27
151
32
181
1.81
2.48
5.9
4.5
—
—
—
0
0
227
1907
1.29
2.42
2.2
2.1
160.87
234.73
u/l
0.95
211
1798
199
1646
1.30
2.39
3.2
2.9
7576.77
8425.31
umol/l
0.07
173
1416
156
1248
1.32
2.39
1.7
1.8
1213.94
1196.33
nmol/l
0.07
120
958
31
176
1.80
2.38
4.3
4.3
7.44
7.42
ph
3.21
26
155
15
66
2.30
2.26
1.3
1.4
1325633.33
174568.11
e6/l
—
9
45
15
66
2.30
2.26
2.0
1.3
65.77
53.05
mu/l
0.18
15
60
11
41
2.71
2.21
1.0
1.0
—
—
—
0
0
30
173
1.77
2.20
1.6
1.6
—
—
—
0
0
152
1225
1.31
2.20
4.2
4.0
647.72
365.51
ng/l
0.48
144
1029
53
355
1.53
2.20
3.0
2.8
0.07
0.24
e6/l
2.82
53
347
191
1588
1.28
2.18
3.7
3.2
0.71
0.76
ug/l
0.46
143
1103
310
2730
1.25
2.18
5.8
5.3
3.40
3.04
ug/l
0.11
275
2431
67
473
1.46
2.17
3.0
2.8
11.09
10.60
g/l
0.36
61
430
26
145
1.82
2.13
4.8
4.6
1.93
2.55
mmol/l
0.61
21
94
31
184
1.72
2.08
4.7
3.3
—
—
—
0
0
70
503
1.44
2.07
5.9
3.9
—
—
—
0
0
22
119
1.88
1.99
2.9
2.2
65.14
61.26
%
0.37
22
119
66
474
1.43
1.97
5.0
5.1
—
—
—
0
0
7
21
3.36
1.97
1.7
1.3
—
—
—
0
0
96
736
1.35
1.96
2.1
1.7
—
—
—
0
0
22
120
1.86
1.95
2.5
2.5
—
—
—
0
0
68
497
1.41
1.85
3.8
4.3
0.04
0.12
%
1.10
27
180
22
123
1.82
1.82
1.2
1.2
0.93
0.86
nmol/l
0.20
22
100
15
73
2.08
1.81
1.1
1.3
—
—
—
0
0
12
53
2.29
1.81
1.4
1.1
1.21
1.67
nmol/l
0.85
12
48
21
116
1.84
1.80
1.1
1.2
—
—
—
0
0
163
1360
1.26
1.79
1.8
1.7
423.11
5140196.92
pmol/l
0.50
139
1109
178
1513
1.24
1.65
5.3
3.6
—
—
—
0
0
19
106
1.82
1.60
1.7
1.5
—
—
—
0
0
19
107
1.80
1.56
1.6
2.7
—
—
—
0
0
65
488
1.37
1.54
2.0
2.2
11.57
12.86
nmol/l
0.52
50
426
12
58
2.09
1.50
4.0
3.1
—
—
—
0
0
15
264
0.56
1.44
1.3
1.3
—
—
—
0
0
18
104
1.75
1.38
1.3
1.5
3.29
5.51
iu/l
—
8
33
21
127
1.67
1.38
1.7
1.7
—
—
—
0
0
17
97
1.77
1.36
4.1
2.7
—
—
—
0
0
9
43
2.11
1.30
1.1
1.1
—
—
—
0
0
183
1597
1.20
1.30
5.3
4.1
0.00
0.01
estimate
0.50
73
525
17
99
1.74
1.28
4.1
2.7
4.03
4.07
mmol/l
0.14
17
99
17
99
1.74
1.28
4.1
2.7
103.53
104.88
mmol/l
0.68
17
99
14
77
1.84
1.26
1.4
1.3
10958.00
117097.95
e6/l
—
5
39
6
25
2.41
1.24
5.0
6.6
—
—
—
0
0
92
752
1.26
1.22
1.6
1.5
—
—
—
0
0
15
86
1.76
1.19
1.3
1.3
—
—
—
0
0
22
141
1.58
1.18
2.9
2.5
14.25
16.20
%
1.74
15
72
14
79
1.79
1.17
1.7
1.2
5.43
6.69
u/ml
—
7
35
0
35
0.00
1.15
0.0
1.4
—
1.00
—
0
35
0
36
0.00
1.14
0.0
1.4
—
82.56
—
0
36
8
40
2.01
1.12
4.1
3.2
—
—
—
0
0
14
81
1.74
1.09
1.5
2.8
—
—
—
0
0
11
193
0.56
1.09
1.8
1.4
—
—
—
0
0
13
74
1.77
1.07
1.8
2.8
0.73
1.87
g/24h
—
8
38
14
82
1.72
1.05
1.4
1.3
624.83
1447.67
e6/l
—
6
52
12
67
1.81
1.05
1.4
1.3
—
—
—
0
0
11
60
1.85
1.03
1.2
1.2
—
—
—
0
0
7
35
2.01
1.00
1.1
1.0
—
—
—
0
0
24
165
1.47
0.98
1.7
1.7
7010.19
16737.34
e6/l
1.20
16
121
36
269
1.36
0.94
6.4
4.5
—
—
—
0
0
25
175
1.44
0.94
1.7
1.3
0.29
0.24
g/l
1.80
25
169
8
42
1.92
0.88
1.4
1.2
—
—
—
0
0
35
265
1.34
0.86
1.1
1.3
—
—
—
0
0
39
301
1.31
0.85
1.5
1.3
157.36
211.75
u/ml
0.41
34
275
8
45
1.79
0.84
1.0
1.2
—
—
—
0
0
29
214
1.37
0.84
4.4
3.9
3.90
3.92
mmol/l
0.07
29
209
6
32
1.88
0.82
1.5
2.0
—
—
—
0
0
8
47
1.71
0.81
1.1
1.7
—
—
—
0
0
64
531
1.23
0.79
1.6
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
6.90
—
0
25
25
182
1.39
0.79
1.7
1.3
1.23
1.19
g/l
0.25
25
175
15
222
0.67
0.78
1.2
1.4
—
—
—
0
0
6
34
1.77
0.76
1.2
1.9
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
1.53
—
0
28
0
28
0.00
0.76
0.0
1.8
—
74.45
—
0
20
9
54
1.68
0.74
1.2
1.3
—
—
—
0
0
5
25
2.01
0.73
1.6
2.3
—
—
—
0
0
54
445
1.23
0.72
1.5
1.4
—
—
—
0
0
7
40
1.76
0.71
1.4
1.9
—
—
—
0
0
5
26
1.93
0.70
1.0
1.2
25.82
28.66
%
—
5
20
5
26
1.93
0.70
3.8
2.9
—
—
—
0
0
7
42
1.67
0.68
1.0
1.4
—
—
—
0
0
7
43
1.63
0.67
2.6
3.1
—
—
—
0
0
16
111
1.45
0.66
1.3
1.6
—
—
—
0
0
5
29
1.73
0.64
1.2
1.8
961.20
920.62
u/ml
—
5
29
35
279
1.27
0.63
1.1
1.1
150.08
129.74
iu/ml
0.12
12
103
22
164
1.35
0.63
1.0
1.1
—
—
—
0
0
54
453
1.21
0.63
4.3
3.6
5.19
5.12
kpa
0.17
54
438
12
79
1.53
0.63
1.4
1.4
—
—
—
0
0
5
30
1.67
0.61
37.6
15.2
—
—
—
0
0
9
141
0.63
0.60
1.4
1.7
—
—
—
0
0
53
446
1.20
0.60
4.3
3.6
7.42
7.40
ph
—
10
56
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
15
105
1.44
0.60
1.3
1.4
—
—
—
0
0
8
52
1.54
0.59
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
13
89
1.47
0.58
1.3
1.0
—
—
—
0
0
6
36
1.67
0.57
1.0
1.3
—
—
—
0
0
10
65
1.55
0.55
2.2
1.9
—
—
—
0
0
12
82
1.47
0.54
1.6
1.6
—
—
—
0
0
9
60
1.51
0.54
1.2
1.2
—
—
—
0
0
54
629
0.85
0.54
5.2
4.6
—
—
—
0
0
13
91
1.44
0.53
1.5
1.4
—
—
—
0
0
10
66
1.52
0.52
1.0
1.1
—
—
—
0
0
22
171
1.30
0.50
1.2
1.2
—
—
—
0
0
13
93
1.41
0.48
1.4
1.1
—
—
—
0
0
13
94
1.39
0.46
1.2
1.1
—
—
—
0
0
21
165
1.28
0.45
7.4
7.9
11.05
11.20
mmol/l
0.10
21
151
21
165
1.28
0.45
7.4
7.9
106.33
105.39
mmol/l
0.60
21
151
24
194
1.25
0.42
8.3
4.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.2
—
130.27
—
0
11
30
250
1.21
0.41
2.6
2.0
373.87
565.11
ug/l
0.34
30
235
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
14
182
0.76
0.39
15.1
12.7
—
—
—
0
0
52
589
0.87
0.39
1.6
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.8
—
—
—
0
0
206
1954
1.08
0.38
4.8
4.1
—
—
—
0
0
8
116
0.69
0.37
1.1
1.3
—
—
—
0
0
50
560
0.88
0.33
3.7
3.3
—
—
—
0
0
175
1843
0.93
0.33
3.5
3.1
—
—
—
0
0
46
408
1.14
0.32
4.8
3.1
—
—
—
0
0
11
83
1.33
0.32
2.5
4.5
—
—
—
0
0
7
57
1.23
0.29
1.4
1.6
—
—
—
0
0
10
129
0.77
0.28
1.0
1.1
—
—
—
0
0
12
94
1.28
0.28
1.3
1.4
105.00
95.33
u/ml
—
6
12
35
310
1.14
0.26
1.4
1.3
—
—
—
0
0
16
132
1.22
0.26
1.2
1.2
—
—
—
0
0
6
84
0.71
0.24
3.8
2.5
—
—
—
0
0
5
38
1.32
0.23
3.8
2.0
—
—
—
0
0
134
1279
1.06
0.22
5.0
4.3
1.02
1.02
kg/l
0.06
25
181
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
18.99
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
16.70
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.16
0.21
3.6
1.7
33.14
34.77
%
—
5
43
0
13
0.00
0.21
0.0
1.0
—
1.81
—
0
7
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.0
1.1
—
89.00
—
0
10
6
52
1.16
0.19
1.3
1.3
—
—
—
0
0
19
167
1.14
0.17
1.7
1.8
11.93
12.70
mg/l
0.17
19
151
14
121
1.16
0.15
1.9
1.6
—
—
—
0
0
14
121
1.16
0.15
1.3
1.3
73.01
33.00
u/l
0.59
14
106
29
265
1.10
0.15
1.7
1.9
—
—
—
0
0
13
113
1.15
0.13
1.6
1.2
—
—
—
0
0
37
345
1.08
0.13
6.3
3.6
—
—
—
0
0
17
189
0.90
0.12
1.2
1.2
—
—
—
0
0
41
387
1.06
0.11
3.0
2.9
6.99
5.51
e9/l
0.23
33
297
29
311
0.93
0.10
1.3
1.4
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
5
61
0.82
0.08
1.2
1.2
—
—
—
0
0
8
74
1.08
0.07
1.1
1.3
—
—
—
0
0
92
907
1.02
0.03
1.2
1.3
19.15
37.25
iu/ml
2.44
31
279
19
181
1.05
0.03
2.7
2.4
105.63
97.57
ug/min
—
8
103
16
168
0.95
0.02
2.7
2.5
—
—
—
0
0
34
332
1.03
0.01
4.9
3.7
—
—
—
0
0
16
167
0.96
0.01
1.4
1.8
50.94
42.77
nmol/l
0.72
16
156
86
854
1.01
0.00
1.3
1.3
17.26
13.92
u/ml
0.12
28
309
11
113
0.97
0.00
3.6
2.7
—
—
—
0
0
19
192
0.99
0.00
1.0
1.1
—
—
—
0
0
11
109
1.01
0.00
2.0
1.2
—
—
—
0
0
14
139
1.01
0.00
2.2
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
18.49
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
9
89
1.01
-0.00
1.1
1.1
1.48
1.57
g/l
—
9
80
5
55
0.91
-0.00
1.0
1.1
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.2
—
—
—
0
0
5
54
0.93
-0.00
1.4
1.2
—
—
—
0
0
5
53
0.94
-0.00
2.8
2.5
—
—
—
0
0
6
67
0.89
-0.00
1.3
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
1.3
1.2
—
—
—
0
0
6
67
0.89
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
100.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_COLON – Carcinoma in situ of colon

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).