Postpartum haemorrhage due to anatomy

O15_POSTPART_HAEMORRH_ANATOMY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O72.1
  • Hospital discharge: ICD-9 6661
  • Cause of death: ICD-10 O72.1
  • Cause of death: ICD-9 6661

2 out of 7 registries used, show all original rules.

5302

4. Check minimum number of events

None

5302

5. Include endpoints

None

5302

6. Filter based on genotype QC (FinnGen only)

4826

Control definitions (FinnGen only)

Control exclude
!(NUMBER_OF_OFFSPRING>0), !(O15_DELIVERY, O15_DELIVERY_PROXY)

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 29763 29763 -
Only index persons 29492 29492 -
Unadjusted period prevalence (%)
Whole population 0.85 0.85 -
Only index persons 1.08 1.08 -
Median age at first event (years)
Whole population - 30.31 -
Only index persons - 30.30 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4826 4826 -
Unadjusted period prevalence (%) 1.71 1.71 -
Median age at first event (years) 30.86 30.86 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5077
Matched controls
50770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
307.7
454
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
15832.0
307.7
4456
23
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.8
307.7
1568
5297
O72.0
ICD-10 Finland
Third-stage haemorrhage
4.5
266.6
733
1846
6661X
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ACUTA ALIA]
+∞
183.4
175
*
MBA04
NOMESCO Finland
Curettage of uterus after delivery
6.9
178.4
283
430
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
2.6
104.4
683
2858
WW500
NOMESCO Finland
Blood transfusion
4.1
96.1
279
718
SPAT1373
SPAT
Combined screening in early pregnancy
2.9
94.3
494
1841
O61.8
ICD-10 Finland
Other failed induction of labour
5.9
88.8
161
279
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
3.4
87.3
336
1046
MAX99
NOMESCO Finland
Assistance to normal delivery
1.7
72.5
1865
12706
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
2.9
64.1
325
1184
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.7
56.9
335
1318
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
2.7
55.6
324
1268
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.5
54.7
353
1452
Z39.2
ICD-10 Finland
Routine postpartum follow-up
1.6
49.8
2738
21827
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
2.2
47.3
410
1919
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
1.7
46.4
1147
7555
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
4.1
41.1
112
275
SPAT1197
SPAT
Extensive health check-up of expecting family
1.5
39.1
2514
20283
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.3
39.0
308
1384
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
1.5
36.9
2450
19805
W92
ICPC
Compl labour/ delivery livebirth
1.9
36.1
492
2712
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
6.7
35.2
56
85
O71.3
ICD-10 Finland
Obstetric laceration of cervix
6.6
34.8
56
86
SPAT1380
SPAT
Postpartum check-up
1.5
34.0
1949
15244
SPAT1200
SPAT
Guidance for breast-feeding and breast care
1.8
32.6
525
3046
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
2.0
32.5
369
1909
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
2.0
30.6
347
1793
SPAT1379
SPAT
Health check-up of pregnant person
1.4
30.2
2241
18241
W90
ICPC
Uncompl labour/delivery livebirth
1.5
30.2
1047
7374
MBB10
NOMESCO Finland
Packing of delivered uterus
7.1
30.1
45
64
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
5.6
28.4
54
98
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
2.9
26.5
124
432
SPAT1195
SPAT
Antenatal classes
1.7
25.7
578
3667
W78
ICPC
Pregnancy
1.4
25.1
2965
25718
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
24.0
175
760
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.6
23.6
595
3879
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1.6
23.3
556
3576
W85
ICPC
Gestational diabetes
1.5
23.0
822
5789
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.4
19.6
1407
11181
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
1.3
19.2
2205
18740
O48
ICD-10 Finland
Prolonged pregnancy
1.5
18.8
555
3745
WX307
NOMESCO Finland
Obstetric epidural analgesia
0.7
17.8
1087
13772
WX234
NOMESCO Finland
Paracervical blockade
0.5
17.5
191
3537
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
7.4
17.4
25
34
Z39.1
ICD-10 Finland
Care and examination of lactating mother
1.6
17.2
391
2479
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
2.4
17.2
117
494
O62.3
ICD-10 Finland
Precipitate labour
3.9
16.9
49
127
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
1.6
16.5
459
3053
O47.9
ICD-10 Finland
False labour, unspecified
1.7
16.2
306
1851
SPAT1189
SPAT
Other ultrasound examination during pregnancy
1.5
15.9
570
3998
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.3
15.2
1437
11793
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.4
15.2
723
5345
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
1.6
14.4
377
2473
Z34
ICD-10 Finland
Supervision of normal pregnancy
1.4
14.4
761
5725
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
14.1
168
884
WX600
NOMESCO Finland
Single shot through catheter
1.8
13.5
211
1212
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.3
13.3
1220
9942
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.2
13.1
113
529
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1.4
13.0
507
3612
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
1.8
12.7
202
1166
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.3
12.6
835
6497
SPAT1324
SPAT
Screening procedure
0.8
12.3
954
11817
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
2.7
12.2
65
245
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.3
11.7
760
5892
WX725
NOMESCO Finland
Noninvasive ventilation
0.4
11.6
54
1371
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
9.2
11.5
23
25
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
1.2
11.4
3439
31889
MBA05
NOMESCO Finland
Curettage of uterus after abortion
1.9
11.1
145
788
XMA22
NOMESCO Finland
General examination of pregnant woman
0.7
10.8
423
5821
N81.6
ICD-10 Finland
Rectocele
1.6
10.7
235
1479
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
1.5
10.7
293
1943
OAA48, ,
SPAT
0.4
10.4
57
1347
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
0.6
10.1
233
3558
TPH04
NOMESCO Finland
Cathetrisation of vein
0.7
10.1
440
5951
Z75.1
ICD-10 Finland
Person awaiting admission to adequate facility elsewhere
2.1
9.9
90
432
WX704
NOMESCO Finland
Intubation
0.6
9.9
143
2445
B01AB05
ATC
enoxaparin; parenteral
1.3
9.8
1032
8511
R45
ICD-10 Finland
Symptoms and signs involving emotional state
2.4
9.8
65
273
D82
ICPC
Teeth/gum disease
1.2
9.8
2195
19615
8834
FHL
Kerviksrupure repair
10.6
9.8
18
17
LX2A3, ,
SPAT
0.6
9.4
124
2173
SPAT1322
SPAT
Pre-employment physical examination
1.8
9.4
138
781
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
1.9
9.3
118
638
TLW12
NOMESCO Finland
Insertion of frozen embryo
1.6
9.2
201
1267
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
1.4
8.9
362
2599
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
1.7
8.9
154
914
SPAT1310
SPAT
Counselling related to known health issue
1.2
8.8
1470
12735
ZXD05
NOMESCO Finland
Urgent procedure
1.2
8.7
1691
14855
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
8.7
2359
21368
WX720
NOMESCO Finland
Own respiration
0.4
8.7
50
1157
O70.22
ICD-10 Finland
III degree perineal tear involving one half or more of external anal sphincter thickness torn during childbirth
2.7
8.7
46
174
ZXA00
NOMESCO Finland
Right side
0.7
8.6
309
4321
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
8.5
1478
12841
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
1.9
8.3
97
510
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.3
8.3
527
4063
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
8.3
761
6163
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
0.4
8.3
52
1163
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
2.3
8.1
58
253
K05.31
ICD-10 Finland
Periodontitis pronounced
0.5
8.1
91
1670
MBW96
NOMESCO Finland
Other operation after delivery or abortion
3.2
8.1
31
98
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
2.1
8.1
74
358
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
1.3
8.0
739
5988
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
1.6
7.9
201
1315
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
2.1
7.8
70
335
-1, ,
NOMESCO Finland
0.8
7.8
1472
16710
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.4
7.8
326
2354
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
1.9
7.7
99
539
Z3231
NOMESCO Finland
Registered nurse
0.8
7.7
607
7555
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
1.2
7.7
1349
11713
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
0.6
7.6
106
1829
Z01.2
ICD-10 Finland
Dental examination
1.2
7.6
2603
23945
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
2.4
7.5
51
218
A78
ICPC
Infectious disease other/NOS
0.5
7.5
49
1074
SPAT1389
SPAT
Visit based on need for special support
1.5
7.4
223
1514
KMAK, ,
NOMESCO Finland
0.9
7.3
2545
27483
OAA30, ,
SPAT
3.5
7.3
24
69
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
0.6
7.3
120
1977
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
1.4
7.2
278
1976
H01CC01
ATC
ganirelix; parenteral
1.4
7.1
295
2130
W29
ICPC
Pregnancy symptom/complaint other
1.3
6.9
461
3580
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.4
6.9
300
2180
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
0.4
6.9
36
863
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.2
6.8
2541
23446
O84.8
ICD-10 Finland
Other multiple delivery
2.5
6.8
41
166
ULC02
NOMESCO Finland
Hysteroscopy
1.4
6.8
241
1689
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
2.5
6.7
39
155
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.5
6.7
195
1314
ZXD10
NOMESCO Finland
Scheduled procedure
0.8
6.7
991
11537
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
3.5
6.7
22
63
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
3.4
6.7
23
68
SCC01
NOMESCO Finland
Fluoride application or other respective small prophylactic procedure
0.5
6.6
50
1040
A10AB01
ATC
insulin (human); parenteral
0.4
6.6
34
819
O47
ICD-10 Finland
False labour
1.6
6.6
141
887
R03CC03
ATC
terbutaline; systemic
0.5
6.5
69
1285
A10AB05
ATC
insulin aspart; parenteral
0.6
6.5
83
1464
A10AE05
ATC
insulin detemir; parenteral
0.5
6.5
45
965
N81.1
ICD-10 Finland
Cystocele
1.5
6.5
173
1145
SPAT1313
SPAT
Guidance and counselling related to accident prevention
2.9
6.5
29
101
RD211, ,
NOMESCO Finland
0.4
6.4
41
905
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
1.5
6.4
162
1060
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.2
6.4
1478
13115
W31
ICPC
Pregnancy, Medical examin/health eval partial
0.5
6.3
53
1063
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
9.2
6.3
12
13
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
0.8
6.3
988
11444
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.8
6.3
879
10293
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
6.2
1518
13516
6661B, ,
ICD-9 Finland
+∞
6.2
6
*
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
1.6
6.2
139
886
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
0.7
6.2
190
2731
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
1.7
6.1
107
641
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
6.1
229
3174
O30.01
ICD-10 Finland
Twin pregnancy with a shared chorionic sac and a separate amniotic sac
2.5
6.0
35
140

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
809
3380
2.66
125.51
2.6
3.0
33.58
32.74
%
1.50
654
2709
571
2476
2.47
79.95
2.3
2.9
7.37
7.34
ph
3.99
404
1791
455
1793
2.69
77.57
1.6
2.2
3.64
3.73
g/l
0.89
426
1695
3668
41627
0.57
63.28
11.6
12.8
332.66
332.75
g/l
0.24
3645
41411
2359
17965
1.58
54.34
1.9
1.9
—
—
—
0
0
341
1557
2.28
41.66
1.6
1.5
486.50
364.10
mu/l
1.41
284
1281
1765
13150
1.52
41.36
1.8
1.8
—
—
—
0
0
3840
42186
0.63
39.57
11.7
12.2
13.32
13.22
%
7.70
3804
41777
1319
9350
1.55
38.21
1.5
1.5
—
—
—
0
0
1317
9470
1.53
35.25
1.5
1.5
1.21
1.16
ratio
1.32
945
5617
99
263
3.82
32.61
1.2
1.2
—
—
—
0
0
1337
10052
1.45
27.42
1.6
1.5
66.66
62.35
ug/l
2.29
1179
8501
408
2311
1.83
27.25
1.9
1.8
0.04
0.03
estimate
0.16
81
1048
59
131
4.55
24.70
1.1
1.0
—
—
—
0
0
960
12921
0.68
24.00
3.6
3.4
0.44
0.33
—
9
67
118
436
2.75
22.69
1.6
1.6
4.88
5.54
mmol/l
8.74
113
395
680
4703
1.51
20.61
1.6
2.0
27.98
28.62
s
3.70
654
4548
2786
24320
1.32
20.53
2.4
2.1
—
—
—
0
0
1153
8818
1.40
20.50
2.3
2.2
—
0.86
—
0
14
1498
12058
1.34
19.06
1.6
1.4
—
—
—
0
0
2782
24430
1.31
18.89
2.0
1.9
—
—
—
0
0
2611
23007
1.28
16.05
2.0
1.9
—
—
—
0
0
303
1849
1.68
15.52
1.3
1.4
17.31
19.09
u/l
0.51
249
1538
2121
18357
1.27
14.58
1.7
1.6
1077.31
1003.95
mu/l
1.88
1809
15792
1033
12863
0.75
14.29
3.4
3.3
1.02
1.26
kg/l
0.80
722
8444
2880
25973
1.25
13.38
2.3
2.2
—
—
—
0
0
1454
17200
0.78
13.30
3.1
3.3
53.57
62.40
e6/l
0.30
924
10507
3080
28011
1.25
13.19
3.1
2.7
—
—
estimate
—
0
0
1519
12847
1.26
12.08
4.1
4.7
1.03
1.04
inr
0.83
1204
10778
1431
16799
0.79
11.86
2.6
2.7
0.16
0.03
0.36
19
183
154
846
1.85
11.43
1.7
2.3
—
—
—
0
0
720
9168
0.75
11.22
3.3
3.2
7.40
7.39
ph
0.32
517
6351
119
607
1.98
11.05
1.5
1.3
—
—
—
0
0
380
5328
0.69
10.76
2.6
2.5
143.09
231.31
ng/l
0.43
166
2040
1111
9160
1.27
10.73
2.6
2.4
7878.58
8051.69
u/l
0.06
607
4395
1278
14977
0.80
9.97
2.3
2.8
26.01
27.38
u/l
0.91
1213
14345
61
249
2.47
9.82
1.1
1.1
15.90
11.40
u/ml
0.21
11
53
75
346
2.19
9.15
1.6
1.7
26.86
23.32
mg/l
0.25
28
140
487
6378
0.74
9.04
2.4
2.3
1.09
1.07
e6/l
0.04
253
3167
1400
12075
1.22
8.71
2.2
2.1
2.72
2.43
mg/l
5.79
1188
10548
2123
19057
1.20
8.65
2.0
1.9
—
—
—
0
0
69
321
2.17
8.29
1.4
1.3
77.00
59.14
u/ml
—
6
27
101
542
1.88
8.18
3.4
3.2
30.10
24.79
mu/l
0.70
101
518
1097
12823
0.82
7.96
2.6
2.7
31.06
65.20
e6/l
1.62
820
9336
4903
48095
1.57
7.80
11.0
9.8
—
—
—
0
0
1055
12352
0.82
7.74
4.0
4.5
—
—
—
0
0
121
705
1.73
7.51
1.3
1.5
—
2488.00
—
0
10
1867
20697
0.85
7.45
9.3
8.5
0.00
0.00
e9/l
1.31
1584
17318
131
2126
0.61
7.44
1.3
1.3
—
—
—
0
0
703
5724
1.26
7.31
1.2
1.2
—
—
—
0
0
121
714
1.71
7.20
1.6
2.1
23.87
24.37
mmol/l
1.79
113
669
598
4796
1.28
7.03
1.9
1.8
0.06
0.04
estimate
0.19
94
1243
20
54
3.71
6.63
1.2
1.1
—
—
—
0
0
19
50
3.81
6.52
1.3
1.4
—
—
—
0
0
134
2079
0.63
6.31
3.8
2.9
1.72
1.46
mmol/l
0.44
121
1775
346
4517
0.75
6.22
1.4
1.4
—
—
—
0
0
33
781
0.42
6.18
1.2
1.2
68.12
68.30
ug/l
0.01
33
781
142
2165
0.65
6.18
3.7
2.8
7.38
7.37
ph
0.39
71
1155
478
5963
0.78
6.09
2.4
2.4
4.88
5.19
e6/l
0.19
238
2748
1282
11281
1.18
6.05
2.1
2.2
13.12
32.31
ng/l
1.01
414
3576
177
1201
1.49
5.93
1.2
1.3
1.22
1.24
nmol/l
0.12
161
1051
624
5134
1.25
5.89
3.0
3.1
—
—
—
0
0
20
60
3.34
5.71
1.2
1.2
—
—
—
0
0
282
3729
0.74
5.55
2.5
2.2
48.00
35.07
u/l
0.44
241
3160
952
10957
0.84
5.54
2.5
2.6
0.21
0.24
e6/l
0.17
673
7656
46
908
0.50
5.31
3.7
4.3
1.13
1.14
mmol/l
0.01
41
811
269
2012
1.36
5.26
1.8
1.8
20.45
19.89
s
0.54
232
1659
69
1186
0.58
5.02
8.3
6.4
—
—
—
0
0
2745
29072
0.88
4.90
3.3
3.5
2.41
3.09
estimate
0.10
627
6745
1486
13423
1.15
4.83
4.0
4.5
1.21
1.21
mmol/l
0.66
1352
12608
194
1399
1.40
4.78
1.6
2.3
7.42
7.41
ph
0.81
148
1175
199
1453
1.38
4.57
1.6
2.4
4.94
5.01
kpa
1.02
190
1393
471
5664
0.81
4.31
1.3
1.3
—
—
—
0
0
694
8043
0.84
4.28
1.6
1.5
—
—
—
0
0
2727
28767
0.89
4.24
3.3
3.4
0.00
0.00
estimate
0.09
637
6772
2770
29188
0.89
4.22
3.4
3.5
0.00
0.16
estimate
0.57
636
6692
54
305
1.78
3.91
1.1
1.1
8.17
10.50
u/ml
0.37
26
219
1446
15791
0.88
3.91
1.6
1.7
1.25
1.26
mmol/l
0.21
1206
14181
709
8143
0.85
3.91
1.7
1.6
—
—
—
0
0
125
866
1.45
3.90
1.4
1.5
—
1.31
—
0
16
78
1216
0.64
3.89
3.0
2.1
129.44
57.47
ng/l
0.81
70
1065
1449
13248
1.13
3.77
5.6
5.5
—
4.48
—
0
9
775
8813
0.86
3.76
2.2
2.3
8.54
9.50
e6/l
0.67
687
7787
163
2192
0.74
3.68
2.5
2.5
1.02
1.02
ratio
0.18
140
1865
477
4019
1.21
3.61
2.0
2.3
5.05
4.81
umol/l
0.33
302
2990
695
7909
0.86
3.39
1.6
1.5
1.23
1.26
mm
1.10
492
5931
1847
19758
0.90
3.37
4.3
4.7
9.00
9.34
umol/l
1.67
1728
18614
102
702
1.46
3.35
1.3
1.2
16.13
21.99
u/ml
—
8
29
220
2798
0.78
3.34
2.1
2.1
0.21
0.25
e6/l
0.13
212
2606
30
149
2.02
3.24
1.1
1.0
3.66
1.20
u/ml
0.36
20
88
187
1434
1.32
3.22
2.7
2.7
23.08
31.52
iu/ml
—
5
60
365
4369
0.82
3.22
2.1
2.0
—
—
—
0
0
155
2051
0.75
3.18
1.7
1.9
—
—
—
0
0
2100
22229
0.91
3.02
3.1
3.2
0.06
0.12
estimate
0.27
554
5793
3688
35755
1.12
3.00
4.5
4.3
1275.82
1564.79
e6/l
0.10
33
393
97
1365
0.70
2.96
3.6
2.6
131.28
132.39
g/l
0.20
92
1328
204
1605
1.28
2.93
1.3
1.3
2.72
5.93
u/ml
0.69
23
145
62
396
1.57
2.93
1.1
1.2
2.09
20.17
u/ml
0.98
11
46
5039
50118
1.73
2.90
17.2
16.4
7.24
6.93
e9/l
14.39
4997
49530
5038
50109
1.70
2.85
17.1
16.3
89.73
89.83
fl
0.92
5020
49951
5038
50111
1.70
2.82
17.1
16.3
29.96
29.98
pg
0.41
5020
49955
5038
50112
1.70
2.81
17.3
16.5
39.99
40.00
%
0.01
5020
49932
203
1607
1.27
2.79
1.3
1.3
5.30
8.08
u/ml
0.52
33
227
5038
50114
1.69
2.78
17.2
16.3
4.39
4.44
e12/l
21.23
4994
49549
392
4594
0.84
2.77
1.9
2.1
5.47
5.79
umol/l
0.17
325
3871
50
309
1.62
2.72
2.0
2.1
—
—
—
0
0
407
3480
1.18
2.67
1.3
1.3
50.20
37.96
au/ml
0.32
15
175
1215
11191
1.11
2.67
1.8
1.8
1.10
0.94
mg/l
1.13
940
8448
25
126
1.99
2.65
1.1
1.1
—
—
—
0
0
177
1389
1.28
2.63
1.1
1.2
840.66
1295.71
pmol/l
0.21
12
112
53
336
1.58
2.62
1.9
2.1
—
—
—
0
0
5038
50128
1.65
2.58
17.3
16.4
130.66
132.36
g/l
24.38
5021
49968
532
4675
1.15
2.49
2.1
2.3
231.87
338.21
ng/l
1.60
382
3656
132
1006
1.32
2.46
1.4
1.3
—
—
—
0
0
62
911
0.68
2.46
1.9
2.2
0.92
1.68
index
0.83
38
462
24
443
0.54
2.43
1.6
1.5
—
—
—
0
0
24
443
0.54
2.43
1.6
1.5
—
—
—
0
0
24
443
0.54
2.43
1.6
1.5
—
—
—
0
0
24
443
0.54
2.43
1.6
1.5
—
—
—
0
0
1030
9450
1.11
2.42
2.2
2.0
290.27
287.75
umol/l
0.50
942
8737
1093
11847
0.90
2.42
2.3
2.7
2.33
2.34
mmol/l
0.12
998
11107
1382
14778
0.91
2.31
3.8
4.0
37.43
37.38
g/l
0.13
1289
13987
940
10234
0.90
2.25
1.6
1.7
—
—
—
0
0
147
1859
0.78
2.23
4.1
2.7
—
—
—
0
0
174
1395
1.26
2.22
1.3
1.2
—
—
—
0
0
12
48
2.50
2.18
1.2
1.0
—
—
—
0
0
104
1371
0.75
2.18
1.3
1.1
—
—
—
0
0
938
10196
0.90
2.18
3.3
3.3
7.59
7.91
mmol/l
1.26
841
9197
156
1948
0.79
2.14
7.9
6.9
—
—
—
0
0
510
5737
0.88
2.13
2.0
2.1
2.39
2.39
mmol/l
0.07
448
5080
5033
50101
1.53
2.11
17.2
16.4
255.34
266.34
e9/l
36.48
4996
49577
88
1182
0.74
2.11
1.3
1.4
316.27
1385.43
e6/l
1.09
70
951
383
4386
0.86
2.08
2.5
2.0
—
—
—
0
0
40
617
0.65
2.06
3.0
3.9
27.65
21.59
u/ml
0.37
40
595
386
4410
0.87
2.03
2.5
2.0
—
—
—
0
0
159
1278
1.25
2.02
2.5
2.3
1.06
1.13
g/l
0.52
143
1143
385
4396
0.87
2.01
2.4
2.0
—
—
—
0
0
87
1161
0.74
2.01
1.2
1.3
18.54
22.40
e6/l
0.15
65
877
18
90
2.00
2.00
1.1
1.0
0.68
0.10
u/ml
—
8
36
155
1244
1.25
2.00
1.1
1.1
0.29
0.21
u/ml
0.15
34
346
4668
46127
1.15
1.97
9.9
10.3
18.30
18.25
mg/l
0.04
3902
37747
675
7426
0.90
1.96
2.2
2.4
527.11
527.16
mosm/kgh2o
0.00
592
6424
421
3714
1.15
1.91
2.4
2.3
20.28
19.41
au/ml
0.07
49
557
13
267
0.49
1.90
1.2
1.3
4.60
5.01
u/l
0.40
13
231
6
155
0.39
1.88
16.7
15.0
1024.33
1152.32
nmol/l
—
6
145
27
158
1.71
1.88
1.7
2.5
31.15
28.70
%
0.52
27
158
197
1636
1.21
1.87
1.1
1.2
—
—
—
0
0
0
54
0.00
1.85
0.0
1.8
—
1.19
—
0
49
70
509
1.38
1.85
1.1
1.1
1347.84
1446.39
miu/ml
0.36
70
509
461
4103
1.14
1.84
1.6
1.6
1075.65
1206.90
nmol/l
2.24
358
3333
85
1121
0.75
1.84
3.4
4.5
—
—
—
0
0
2900
29901
0.93
1.83
6.2
6.3
69.37
69.73
u/l
0.27
2719
28483
1646
15620
1.08
1.80
4.6
4.9
1.21
1.21
mmol/l
2.57
1416
13565
353
4020
0.87
1.80
2.5
2.1
—
—
—
0
0
108
1374
0.78
1.79
1.3
1.3
176.84
150.64
au/ml
1.80
31
334
211
1773
1.20
1.78
1.4
1.3
18.70
31.91
u/ml
—
10
115
271
2329
1.17
1.77
1.6
1.7
—
—
—
0
0
671
7340
0.90
1.77
3.2
3.6
95.86
81.33
mg/l
0.56
442
4818
104
809
1.29
1.76
1.9
1.9
—
—
—
0
0
156
1275
1.23
1.75
2.0
2.8
374.50
366.98
mg/l
0.03
62
589
17
88
1.93
1.74
1.1
1.0
0.17
0.17
u/ml
—
7
32
39
257
1.52
1.73
1.6
1.5
0.00
0.01
estimate
0.50
39
257
2168
22554
0.93
1.71
3.0
3.1
6.32
6.28
ph
1.21
1294
12849
888
8230
1.10
1.71
1.6
1.6
3.18
3.23
ratio
0.64
626
5762
114
902
1.27
1.70
1.4
1.4
1381.82
1023.95
titre
0.57
11
167
684
7446
0.91
1.64
3.8
4.2
14.77
13.39
mg/mmol
0.30
431
4883
6
145
0.41
1.64
16.0
11.7
653.00
671.37
nmol/l
—
6
138
120
965
1.25
1.58
4.0
3.3
—
—
—
0
0
65
482
1.35
1.56
1.0
1.0
—
—
—
0
0
66
875
0.75
1.53
1.1
1.1
—
—
—
0
0
342
3028
1.14
1.52
1.3
1.2
10.22
10.11
u/l
0.06
298
2564
17
93
1.83
1.51
1.1
1.0
0.03
0.06
u/ml
—
10
38
55
400
1.38
1.50
1.1
1.4
1015.25
384.09
mu/l
0.75
55
382
248
2151
1.16
1.48
2.4
2.4
4.11
3.78
iu/l
0.27
103
1021
20
116
1.73
1.48
1.1
1.1
—
—
—
0
0
170
2013
0.84
1.47
6.2
7.1
96.93
97.02
%
0.07
162
1930
195
1662
1.18
1.46
1.1
1.1
1.69
1.75
u/ml
0.03
84
803
31
204
1.52
1.42
1.5
2.5
—
—
—
0
0
21
339
0.62
1.41
1.0
1.6
1.48
1.20
promille
0.42
14
267
3330
32558
1.07
1.40
3.7
3.6
58.08
55.09
ug/l
0.80
3103
31303
53
389
1.37
1.39
1.1
1.4
4.38
6.38
ug/l
3.22
45
352
1227
12940
0.93
1.39
2.3
2.4
52.43
56.52
u/l
2.75
1121
12195
56
415
1.35
1.38
1.1
1.4
71.93
73.18
%
0.26
56
397
22
349
0.63
1.38
1.6
3.1
—
—
—
0
0
42
583
0.72
1.35
2.8
2.8
—
—
—
0
0
433
4768
0.90
1.33
1.4
1.3
—
—
—
0
0
24
370
0.65
1.33
10.7
13.5
0.63
0.59
mmol/l
0.78
24
345
109
1327
0.82
1.30
1.6
1.7
5.28
4.42
ug/l
0.19
97
1168
2411
24843
0.94
1.29
6.5
7.0
3.94
4.01
e9/l
0.83
2144
21876
46
335
1.38
1.28
1.1
1.1
294.10
296.26
mg/l
0.08
39
317
145
1223
1.19
1.26
1.1
1.1
15.84
14.82
au/ml
0.08
45
397
166
1419
1.18
1.24
1.1
1.1
4.87
4.39
u/ml
0.13
64
627
181
2093
0.86
1.22
6.6
5.9
1.31
1.23
mmol/l
0.38
174
2057
18
108
1.67
1.22
1.0
1.0
0.44
0.14
u/ml
—
8
62
122
1456
0.83
1.20
1.3
1.3
—
—
—
0
0
36
501
0.72
1.20
1.3
1.3
0.63
0.70
ratio
0.38
16
298
695
6480
1.08
1.20
1.5
1.4
3.31
3.38
mmol/l
0.94
447
4132
40
547
0.73
1.20
1.9
1.2
—
0.12
nmol/l
—
0
9
15
86
1.75
1.18
1.1
1.2
—
—
—
0
0
15
86
1.75
1.18
1.1
1.2
—
—
—
0
0
15
86
1.75
1.18
1.1
1.2
—
—
—
0
0
2570
25009
1.06
1.18
3.5
3.9
5.92
6.00
mmol/l
1.32
1995
21537
374
3393
1.11
1.16
1.3
1.3
3.49
3.66
ug/l
0.32
348
3243
1619
15561
1.06
1.15
3.3
3.4
0.01
0.00
estimate
0.63
610
6592
173
1996
0.86
1.15
1.4
1.7
0.20
0.24
mg/l
0.44
53
786
129
1088
1.19
1.14
1.3
1.3
2.84
4.07
u/ml
1.18
51
475
187
1627
1.16
1.14
1.1
1.1
2.42
1.00
u/ml
0.61
73
683
58
448
1.30
1.13
1.7
1.5
0.52
0.49
e9/l
0.48
58
448
271
2421
1.13
1.12
1.4
1.3
—
—
—
0
0
139
1624
0.85
1.10
1.6
1.5
28.29
36.32
nmol/l
3.36
124
1528
12
206
0.58
1.08
1.9
1.5
121.18
123.43
nmol/l
0.06
12
206
240
2693
0.89
1.07
1.1
1.1
0.52
0.58
ratio
0.64
17
232
209
2365
0.88
1.07
6.1
6.8
7.41
7.42
ph
1.57
107
1318
468
4321
1.09
1.04
1.2
1.3
184.41
153.67
u/ml
0.43
441
4041
7
34
2.06
1.02
1.0
1.1
—
—
—
0
0
37
496
0.74
1.01
1.1
1.2
—
—
—
0
0
311
3424
0.90
1.01
4.2
4.1
1.13
0.93
%
0.31
57
708
545
5077
1.08
0.99
1.2
1.2
—
—
—
0
0
216
2424
0.89
0.99
1.2
1.3
0.43
0.94
u/ml
—
6
169
311
3418
0.90
0.98
4.3
4.3
0.10
0.37
%
0.68
51
568
33
240
1.38
0.98
1.2
1.2
—
—
—
0
0
31
424
0.73
0.97
1.5
1.4
—
—
—
0
0
14
224
0.62
0.97
1.9
1.9
26.79
28.44
%
0.24
14
219
170
1490
1.15
0.97
1.1
1.1
4.34
4.28
u/ml
0.01
72
739
157
1795
0.87
0.96
5.2
6.3
5.76
6.03
mmol/l
0.32
150
1746
20
133
1.51
0.94
5.0
2.1
11334.62
4191.74
mg/l
0.26
13
95
7
37
1.89
0.94
1.0
1.1
1.13
1.33
umol/24h
—
7
37
38
499
0.76
0.92
1.2
1.4
—
—
—
0
0
3405
33496
1.05
0.92
2.8
2.7
26.76
28.60
u/l
1.46
3274
32429
112
1305
0.86
0.90
1.2
1.2
258.02
239.99
u/ml
0.31
64
911
19
277
0.68
0.88
1.1
1.1
—
—
—
0
0
211
2350
0.89
0.87
6.1
6.7
15.39
14.52
kpa
0.81
202
2262
211
2349
0.89
0.87
6.1
6.7
4.83
4.88
kpa
0.41
203
2261
13
205
0.63
0.87
1.8
1.9
0.12
0.20
e9/l
—
7
90
15
229
0.65
0.87
1.7
2.5
12.89
15.37
index
—
9
134
208
2315
0.89
0.86
6.0
6.8
-0.47
0.36
mmol/l
2.04
149
1752
28
379
0.74
0.85
5.5
5.5
339.70
368.80
umol/l
0.42
23
326
304
3316
0.91
0.85
4.2
4.2
0.24
0.16
%
0.36
50
601
6
31
1.94
0.84
1.0
1.0
0.04
0.32
u/ml
—
6
31
607
5720
1.07
0.84
2.1
2.3
3.89
4.28
e9/l
3.07
505
5282
4594
46254
0.93
0.83
9.6
10.3
64.15
64.25
umol/l
0.18
4516
45832
2276
23297
0.96
0.81
5.3
5.4
0.18
0.18
e9/l
0.65
2061
21123
16
237
0.67
0.81
1.8
1.7
39.61
46.76
%
—
9
137
10
165
0.61
0.81
3.7
3.2
53.00
43.28
umol/l
—
10
153
881
8409
1.06
0.81
2.8
2.6
126.17
93.03
ug/g
1.67
666
6640
823
7841
1.06
0.81
2.8
3.1
—
—
—
0
0
7
123
0.57
0.77
2.9
2.4
15.62
21.51
ug/l
—
7
123
220
1995
1.11
0.77
1.2
1.1
3.22
2.22
u/ml
0.49
109
1027
34
439
0.77
0.76
1.9
1.2
0.16
0.15
nmol/l
0.17
22
299
538
5070
1.07
0.76
1.2
1.2
—
—
—
0
0
223
2450
0.91
0.75
2.9
2.9
1.23
1.23
mmol/l
0.12
185
2102
37
468
0.79
0.72
2.0
1.2
—
—
nmol/l
—
0
0
467
4964
0.93
0.72
1.6
1.7
—
—
—
0
0
25
332
0.75
0.70
1.0
1.1
—
—
—
0
0
2194
22422
0.96
0.70
5.3
5.4
0.50
0.51
e9/l
2.75
1978
19994
60
717
0.83
0.69
1.0
1.0
—
—
—
0
0
302
3258
0.92
0.69
4.1
4.0
0.86
0.63
%
0.45
61
661
469
4423
1.07
0.67
3.9
3.6
4.58
4.63
pmol/l
0.64
421
4081
99
1131
0.87
0.66
1.1
1.1
—
—
—
0
0
27
351
0.77
0.66
1.3
1.3
—
—
—
0
0
446
4730
0.94
0.65
2.5
2.8
0.84
0.84
mmol/l
0.23
415
4513
37
461
0.80
0.65
1.1
1.2
—
—
—
0
0
706
7385
0.95
0.65
1.3
1.3
—
—
—
0
0
42
340
1.24
0.65
1.0
1.3
—
—
—
0
0
92
802
1.15
0.64
2.3
2.3
—
—
—
0
0
190
1732
1.10
0.63
1.1
1.1
6.79
5.84
u/ml
0.36
88
944
253
2338
1.09
0.63
2.2
2.1
7.55
6.69
iu/ml
0.26
62
585
30
381
0.79
0.62
1.1
1.1
—
—
—
0
0
47
387
1.22
0.62
1.3
1.2
11.09
8.92
mm/h
0.47
47
387
242
2233
1.09
0.62
1.6
1.7
8.83
10.06
u/ml
0.27
59
648
17
121
1.41
0.62
1.3
1.2
—
—
—
0
0
673
6437
1.05
0.60
1.3
1.3
134.39
146.54
u/ml
0.35
253
2633
0
20
0.00
0.60
0.0
2.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.5
—
184.65
—
0
20
68
584
1.17
0.59
1.2
1.2
1.07
1.05
ratio
0.37
57
491
2201
22432
0.97
0.58
5.3
5.4
0.04
0.04
e9/l
1.40
1980
19969
7
113
0.62
0.58
56.3
42.7
8.17
7.48
ug/l
—
7
106
500
5257
0.95
0.57
1.4
1.5
390.68
278.39
mu/l
0.72
433
4684
186
1706
1.09
0.57
2.9
2.4
74.00
71.12
e9/l
0.44
134
1185
92
812
1.14
0.56
3.7
3.2
25.03
23.04
mg/l
0.22
53
531
173
1584
1.10
0.55
1.9
2.1
67.97
67.57
g/l
0.30
161
1497
487
4633
1.06
0.55
2.1
2.3
6.24
6.30
ph
0.64
263
2963
112
1003
1.12
0.54
3.0
3.1
58.52
58.52
%
0.00
112
1003
12
171
0.70
0.54
2.5
1.7
106.92
106.27
mmol/l
0.34
12
171
12
170
0.71
0.53
2.5
1.7
3.96
3.89
mmol/l
0.37
12
170
39
322
1.21
0.53
1.3
1.4
20.54
22.98
umol/l
0.26
34
300
15
108
1.39
0.53
1.0
1.1
—
26.00
—
0
5
24
187
1.28
0.52
1.6
1.5
893.44
18997.93
e6/l
—
9
126
6
98
0.61
0.52
5.2
2.0
6.45
7.06
mmol/l
—
6
98
43
510
0.84
0.50
1.0
1.1
—
—
—
0
0
582
5585
1.05
0.49
2.0
2.1
2.55
2.54
g/l
0.15
522
5130
114
1031
1.11
0.48
1.1
1.1
116.93
116.59
%
0.06
107
940
7
110
0.64
0.48
1.1
1.4
—
—
—
0
0
7
46
1.52
0.48
1.0
1.4
48.14
77.04
mu/l
—
7
37
7
46
1.52
0.48
1.0
1.1
9.57
10.12
pmol/l
—
7
46
31
377
0.82
0.48
4.1
3.0
32.03
27.46
mg/l
0.16
23
322
33
272
1.21
0.47
3.2
2.7
0.80
0.87
e9/l
0.43
33
264
17
222
0.76
0.47
1.5
1.8
—
—
—
0
0
12
165
0.73
0.46
2.5
1.7
1.22
1.20
mmol/l
0.65
12
165
234
2495
0.93
0.45
1.1
1.1
—
—
—
0
0
15
112
1.34
0.44
1.0
1.2
—
—
—
0
0
3971
39994
0.97
0.44
5.4
5.0
14.15
14.14
pmol/l
0.14
3732
38288
446
4269
1.05
0.43
1.4
1.4
—
—
—
0
0
5
31
1.61
0.43
2.2
3.2
—
—
—
0
0
6
93
0.64
0.42
1.0
1.4
8.80
8.74
mmol/l
—
6
93
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
1493
15229
0.97
0.41
1.3
1.4
1.12
1.45
u/ml
1.08
428
4851
516
5362
0.96
0.41
1.5
1.6
—
—
—
0
0
8
59
1.36
0.41
1.5
1.8
41.06
41.81
g/l
—
8
59
98
1077
0.91
0.40
1.9
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
0.09
—
0
8
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
35
296
1.18
0.40
2.4
3.2
1.63
1.42
g/24h
0.24
20
179
5
35
1.43
0.39
1.0
1.0
—
—
—
0
0
64
569
1.13
0.39
1.9
2.3
2.22
1.94
mmol/l
0.26
26
303
0
19
0.00
0.39
0.0
1.0
—
0.42
—
0
12
0
19
0.00
0.39
0.0
2.4
—
218.04
—
0
19
61
541
1.13
0.39
1.1
1.1
3.66
7.55
iu/ml
2.95
19
163
43
372
1.16
0.38
1.1
1.1
—
0.32
—
0
7
268
2542
1.06
0.38
2.3
2.4
1.67
1.67
%
0.05
238
2286
32
377
0.85
0.38
4.0
3.0
26.32
42.20
mg/l
0.72
23
322
30
252
1.19
0.37
2.3
2.6
202.92
160.55
au/ml
—
5
46
50
568
0.88
0.37
1.1
1.1
18.85
14.89
u/ml
0.41
21
274
10
72
1.39
0.36
1.0
1.0
0.03
0.08
u/ml
—
10
72
27
321
0.84
0.36
3.4
3.0
1.45
1.72
ratio
0.25
11
177
61
545
1.12
0.35
1.0
1.1
1.32
1.43
g/l
2.19
52
511
67
603
1.11
0.35
1.3
1.2
—
—
—
0
0
3917
38927
1.03
0.34
2.9
3.0
1.09
1.11
mmol/l
1.04
3734
37628
811
7901
1.03
0.34
1.4
1.4
590.59
568.81
titre
0.10
170
1585
70
773
0.90
0.34
1.5
2.2
129.53
131.38
g/l
0.36
49
664
10
133
0.75
0.33
1.0
1.1
—
—
—
0
0
16
127
1.26
0.33
3.6
3.0
—
—
—
0
0
99
1073
0.92
0.33
1.2
1.3
—
—
—
0
0
50
444
1.13
0.33
1.0
1.0
—
—
—
0
0
6
46
1.30
0.33
1.5
1.4
0.67
1.17
u/field
—
6
46
6
86
0.70
0.33
1.8
1.5
—
—
—
0
0
42
369
1.14
0.32
2.0
2.2
44.27
44.17
%
0.02
42
361
309
3225
0.96
0.32
3.0
2.9
—
—
—
0
0
57
634
0.90
0.32
1.1
1.2
29.82
36.07
mg/l
1.30
49
533
15
187
0.80
0.32
1.0
1.1
—
—
—
0
0
112
1205
0.93
0.32
1.3
1.3
112.50
110.66
titre
—
8
121
37
420
0.88
0.29
1.3
3.4
5.89
6.35
mmol/l
0.93
31
329
1085
11059
0.98
0.29
1.4
1.4
21.95
21.80
iu/ml
0.01
283
3142
2074
20499
1.02
0.28
5.4
5.4
7.80
7.90
%
1.32
1937
19396
3996
39759
1.02
0.28
3.2
3.3
5.37
5.44
mmol/l
5.19
3737
38010
2065
20412
1.02
0.28
5.4
5.4
0.66
0.66
%
0.21
1921
19183
2069
20452
1.02
0.28
5.4
5.4
2.72
2.73
%
0.08
1928
19295
56
617
0.91
0.28
1.1
1.1
175.44
195.86
mg/l
1.29
48
550
689
7056
0.97
0.27
1.7
1.5
62.37
60.22
ug/l
0.72
689
7056
9
118
0.76
0.27
2.1
2.1
135.22
157.88
nmol/l
—
9
109
14
172
0.81
0.27
1.0
1.3
—
—
—
0
0
210
2007
1.05
0.26
1.1
1.1
1.95
5.02
eliau/ml
2.66
30
342
27
310
0.87
0.26
1.1
1.0
—
—
—
0
0
11
86
1.28
0.26
1.1
1.5
—
6.12
—
0
9
110
1172
0.94
0.26
1.3
1.3
1386.67
1012.34
titre
—
6
47
76
703
1.08
0.25
1.6
2.0
136.01
222.55
ug/l
0.83
61
604
709
7249
0.97
0.25
1.5
1.5
7942067.39
50278113.39
pmol/l
3.78
617
6482
1001
10191
0.98
0.25
1.3
1.3
6.97
6.75
u/ml
0.06
398
4499
123
1159
1.06
0.25
1.1
1.1
3.55
3.32
eliau/ml
0.05
61
622
34
301
1.13
0.25
6.9
6.9
31.60
74.74
ug/l
0.35
25
204
2288
23101
0.98
0.25
5.2
5.3
1.95
1.99
e9/l
0.46
2093
21129
108
1014
1.07
0.25
1.2
1.2
—
—
—
0
0
3699
37183
0.98
0.24
3.5
3.8
35.49
35.92
mmol/mol
4.06
3524
35884
21
244
0.86
0.24
4.8
2.0
0.85
0.88
%
0.08
11
136
18
212
0.85
0.24
1.2
1.5
71.78
89.52
nmol/24h
0.74
18
212
6
85
0.71
0.24
1.0
1.6
—
—
—
0
0
886
9022
0.98
0.23
1.7
1.9
121.92
132.69
u/l
0.37
846
8663
28
246
1.14
0.23
1.2
1.7
1.53
2.56
u/field
1.13
17
148
4214
41982
1.02
0.23
3.3
3.5
4.71
4.74
mmol/l
1.62
4015
40738
5
38
1.32
0.23
1.2
2.5
—
—
—
0
0
72
774
0.93
0.23
1.7
1.5
0.63
0.57
g/l
0.32
60
611
180
1880
0.96
0.22
3.4
3.7
38.50
32.03
ug/l
0.06
113
1263
91
968
0.94
0.22
2.1
2.9
1.10
1.20
mg/l
1.29
84
921
2126
21067
1.02
0.21
5.2
5.2
56.58
56.53
%
0.09
2026
20268
1484
15019
0.98
0.21
2.2
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
40.73
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
375.00
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
494
4824
1.03
0.21
2.1
2.1
24.70
24.57
%
0.07
446
4458
13
156
0.83
0.21
1.0
1.0
—
—
—
0
0
13
156
0.83
0.21
1.0
1.0
—
—
—
0
0
13
156
0.83
0.21
1.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
7.8
—
108.92
—
0
12
0
13
0.00
0.21
0.0
1.4
—
479.31
—
0
13
544
5559
0.98
0.20
1.8
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
1.40
—
0
8
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
9
113
0.80
0.20
1.0
1.2
—
—
—
0
0
9
113
0.80
0.20
1.6
1.5
—
—
—
0
0
15
176
0.85
0.19
1.1
1.2
—
52.20
u/ml
—
0
5
6
50
1.20
0.19
1.0
1.3
305.33
344.23
pmol/l
—
6
40
110
1045
1.05
0.19
2.1
2.1
10.05
10.32
mg/l
0.15
105
999
4198
41843
1.02
0.19
3.3
3.4
1.51
1.52
mmol/l
1.16
3996
40504
31
279
1.11
0.19
1.1
1.1
—
—
—
0
0
21
184
1.14
0.19
1.2
1.0
0.92
0.94
u/ml
0.01
15
161
49
453
1.08
0.18
2.5
2.5
1248.98
1434.66
e6/l
1.23
44
377
58
622
0.93
0.18
3.0
3.4
1375.56
122.54
u/ml
0.65
49
531
170
1636
1.04
0.18
1.1
1.1
—
—
—
0
0
315
3234
0.97
0.18
1.1
1.1
—
—
—
0
0
7
61
1.15
0.17
1.4
1.2
—
—
—
0
0
48
517
0.93
0.17
1.3
1.3
2.91
3.08
g/l
0.32
36
369
48
517
0.93
0.17
1.3
1.3
0.38
0.37
g/l
0.11
38
371
325
3332
0.97
0.17
2.2
2.5
10.77
10.49
g/l
0.77
294
3116
4659
46499
1.02
0.17
8.2
8.6
22.95
23.32
u/l
0.62
4514
45562
17
194
0.88
0.16
1.1
2.3
96.56
211.55
umol/l
—
9
99
169
1632
1.04
0.16
1.1
1.1
—
—
—
0
0
8
70
1.14
0.16
1.0
1.1
—
—
—
0
0
108
1033
1.05
0.16
1.2
1.2
—
—
—
0
0
25
277
0.90
0.16
1.4
1.2
300.00
180.00
titre
—
6
48
8
72
1.11
0.16
1.1
1.7
—
—
—
0
0
707
6965
1.02
0.16
1.3
1.3
21.96
20.58
iu/l
0.59
638
6089
42
390
1.08
0.15
1.0
1.1
—
—
—
0
0
61
575
1.06
0.15
1.1
1.0
0.59
0.34
u/ml
0.38
13
126
23
255
0.90
0.15
1.0
1.4
—
—
—
0
0
23
255
0.90
0.15
1.1
1.1
5.12
38.92
u/ml
0.45
14
148
252
2455
1.03
0.15
2.4
2.1
0.23
0.23
g/l
0.35
239
2335
9
80
1.13
0.15
1.1
1.2
—
—
—
0
0
14
121
1.16
0.15
1.9
2.6
—
—
—
0
0
57
537
1.06
0.14
1.2
1.1
—
—
—
0
0
39
362
1.08
0.14
1.7
2.0
13.62
12.60
%
0.35
39
356
40
372
1.08
0.14
2.9
2.4
180.60
216.02
e6/l
1.20
35
298
20
179
1.12
0.14
1.1
1.1
—
—
—
0
0
50
530
0.94
0.13
1.8
1.7
10.21
10.41
g/l
0.15
44
502
23
209
1.10
0.13
1.1
1.5
4.25
2.44
u/field
0.43
16
148
4393
44017
0.99
0.13
6.0
5.8
1.58
1.62
mu/l
1.86
4156
42626
277
2830
0.98
0.12
1.2
1.2
—
—
—
0
0
19
171
1.11
0.12
1.0
1.1
16.28
34.70
iu/ml
2.56
19
171
318
3242
0.98
0.12
4.0
4.7
1.04
1.04
mmol/l
0.02
292
3028
21
231
0.91
0.12
1.1
1.3
129.86
146.50
mmol/24h
1.01
21
231
429
4222
1.02
0.12
1.4
1.3
235.42
236.31
miu/ml
0.02
247
2198
191
1862
1.03
0.12
3.1
3.1
58.89
69.68
ng/l
2.12
173
1707
118
1141
1.03
0.12
1.3
1.3
—
—
—
0
0
49
517
0.95
0.11
1.3
1.3
7.32
6.45
g/l
1.01
39
371
40
424
0.94
0.11
1.3
1.1
116.38
123.11
pmol/l
0.35
40
424
474
4676
1.02
0.10
1.3
1.4
—
—
—
0
0
170
1659
1.03
0.10
2.1
2.1
0.23
0.23
g/l
0.40
163
1589
1231
12401
0.99
0.10
1.4
1.4
2.03
2.04
g/l
0.09
814
8325
16
144
1.11
0.10
1.1
1.1
—
—
—
0
0
96
991
0.97
0.09
1.1
1.2
102.54
11223.36
iu/ml
0.63
37
239
5
46
1.09
0.09
1.0
1.1
102.40
89.04
titre
—
5
46
358
3528
1.02
0.09
1.1
1.1
55.83
215.84
titre
2.58
12
107
897
9042
0.99
0.09
1.6
1.5
20.66
20.31
nmol/l
0.35
776
8190
1728
17362
0.99
0.08
2.7
2.8
0.02
0.03
estimate
0.62
544
5805
175
1716
1.02
0.08
2.1
2.1
1.17
1.17
g/l
0.03
169
1648
938
9314
1.01
0.08
2.7
3.0
99.06
98.85
%
0.11
907
9036
49
511
0.96
0.08
1.3
1.3
—
—
—
0
0
632
6264
1.01
0.08
2.1
2.1
15.10
15.29
umol/l
0.29
576
5857
14
127
1.10
0.07
3.1
2.0
—
—
—
0
0
6
72
0.83
0.07
1.7
1.3
62.50
60.08
ug/l
—
6
72
2149
21412
1.01
0.07
5.3
5.3
30.03
30.00
%
0.07
2046
20452
8
74
1.08
0.07
4.1
2.3
14.77
16.51
%
—
8
74
44
422
1.04
0.07
1.8
1.6
3.21
2.72
u/ml
0.09
14
105
8
93
0.86
0.06
1.5
1.5
—
—
—
0
0
27
285
0.95
0.06
1.3
1.3
65.48
65.86
umol/l
0.06
27
285
30
285
1.05
0.06
1.4
1.8
39.76
41.98
%
0.12
21
167
9
104
0.87
0.06
1.1
1.1
—
—
—
0
0
4223
42280
0.99
0.06
7.7
8.6
3.87
3.87
mmol/l
0.25
4054
41290
12
109
1.10
0.06
1.2
1.6
8.54
8.46
ug/l
0.02
12
109
51
493
1.03
0.06
1.2
1.2
3.09
1.69
u/ml
0.37
26
266
45
434
1.04
0.06
1.5
1.9
—
—
—
0
0
24
253
0.95
0.05
1.4
1.1
6.73
5.86
nmol/l
0.54
24
244
337
3400
0.99
0.05
2.0
2.2
29.00
28.88
u/ml
0.01
328
3292
60
616
0.97
0.05
1.5
2.3
—
—
—
0
0
25
238
1.05
0.05
2.0
2.5
—
—
—
0
0
82
803
1.02
0.04
1.0
1.1
—
—
—
0
0
55
565
0.97
0.04
1.7
1.7
7103.59
7965.19
e6/l
0.14
46
399
20
189
1.06
0.04
2.3
2.1
—
—
—
0
0
37
357
1.04
0.04
2.8
2.3
476.71
535.00
e6/l
0.62
31
273
28
268
1.05
0.04
1.1
1.2
—
—
—
0
0
12
130
0.92
0.04
1.4
1.6
71.42
76.15
ng/l
0.17
12
130
62
605
1.03
0.04
4.7
4.2
115.01
88.55
u/ml
0.18
29
219
249
2513
0.99
0.04
1.7
1.8
1.19
1.36
g/l
2.66
228
2383
25
239
1.05
0.04
1.5
2.2
17.26
148.56
ug/l
0.90
25
230
363
3656
0.99
0.04
1.2
1.2
—
—
—
0
0
1990
19857
1.00
0.04
2.4
2.4
74.13
72.84
nmol/l
1.52
1863
18981
28
269
1.04
0.04
3.3
3.4
7.99
8.24
mg/l
0.12
16
220
19
180
1.06
0.04
1.1
1.2
—
—
—
0
0
18
190
0.95
0.04
2.7
1.8
2.62
2.62
mg/l
0.00
18
184
20
190
1.05
0.04
1.3
1.5
5.12
5.22
mmol/l
0.40
20
190
4221
42238
1.00
0.03
7.7
8.5
139.34
139.42
mmol/l
1.67
4075
41352
39
380
1.03
0.02
1.7
2.1
77.59
76.54
%
0.27
39
371
41
401
1.02
0.02
2.2
2.3
17.11
25.21
mg/l
1.94
27
279
469
4674
1.00
0.02
1.7
1.6
—
—
—
0
0
136
1349
1.01
0.02
2.2
2.1
—
—
—
0
0
2129
21311
1.00
0.01
2.2
2.2
—
—
—
0
0
1476
14741
1.00
0.01
1.8
1.8
99.16
98.88
pmol/l
0.10
881
8472
15
157
0.96
0.01
1.0
1.0
29.23
7.47
u/ml
0.39
15
157
63
622
1.01
0.01
1.1
1.0
1.27
1.64
u/ml
0.14
17
200
324
3251
1.00
0.01
1.2
1.2
—
—
—
0
0
148
1471
1.01
0.01
1.2
1.3
30.78
38.76
u/ml
0.24
12
120
170
1692
1.00
0.01
1.1
1.1
—
—
—
0
0
11
116
0.95
0.00
2.1
1.8
—
—
—
0
0
23
236
0.97
0.00
2.3
1.7
—
—
—
0
0
470
4693
1.00
0.00
2.0
2.0
390.34
378.06
nmol/l
0.80
444
4400
63
636
0.99
0.00
1.9
1.9
0.57
1.43
ug/l
2.08
53
569
17
172
0.99
0.00
1.2
1.4
—
—
—
0
0
26
262
0.99
0.00
3.7
2.2
31.92
32.10
pg
0.07
26
262
62
615
1.01
0.00
1.1
1.0
0.29
1.04
u/ml
2.22
13
150
65
645
1.01
0.00
2.4
2.0
6.47
5.31
mmol/24h
1.57
58
601
19
186
1.02
0.00
1.4
1.2
27.37
27.11
s
0.11
19
186
4215
42148
1.00
0.00
3.4
3.6
2.81
2.84
mmol/l
1.16
3994
40758
16
157
1.02
0.00
1.2
1.2
6.09
6.03
mmol/l
0.05
16
148
42
416
1.01
0.00
1.0
1.1
—
—
—
0
0
89
893
1.00
0.00
1.4
1.3
320.33
336.40
ug/g
0.28
33
402
16
161
0.99
0.00
1.1
1.1
—
—
—
0
0
240
2403
1.00
0.00
1.4
1.5
0.61
0.54
nmol/l
0.29
207
2003
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1.20
—
0
6
6
64
0.94
-0.00
3.0
2.0
23.50
24.62
mg/l
—
6
64
0
8
0.00
-0.00
0.0
1.1
—
4.21
—
0
8
6
62
0.97
-0.00
1.0
1.5
—
126.98
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.03
—
0
5
8
79
1.01
-0.00
1.1
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
50
1.00
-0.00
1.8
2.0
—
—
—
0
0
8
88
0.91
-0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
30.73
—
0
9
6
61
0.98
-0.00
2.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
68.71
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
75
0.93
-0.00
10.4
6.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint O15_POSTPART_HAEMORRH_ANATOMY and mortality.

Females

Parameter HR [95% CI] p-value
O15_POSTPART_HAEMORRH_ANATOMY 0.525 [0.4, 0.68] < 0.001
Birth year 0.996 [0.99, 1.0] 0.323

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 21640 females with O15_POSTPART_HAEMORRH_ANATOMY died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POSTPART_HAEMORRH_ANATOMY.

N-year risk Females Males
1 0.046% No data
5 0.315% No data
10 0.742% No data
15 1.405% No data
20 2.702% No data

Relationships between endpoints

Index endpoint: O15_POSTPART_HAEMORRH_ANATOMY – Postpartum haemorrhage due to anatomy

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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