No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1598 |
4. Check minimum number of eventsNone |
1598 |
5. Include endpointsNone |
1598 |
6. Filter based on genotype QC (FinnGen only) |
1435 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_CIRCULATO_SYSTEM
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Bicuspidal aortic valve syndrome
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of aortic and mitral valves
- Left ventricular outflow tract obstruction, narrow definition
- Congenital malformations of heart and great arteries
- Congenital malformations of the circulatory system
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1435 | 468 | 967 |
| Unadjusted period prevalence (%) | 0.35 | 0.17 | 0.44 |
| Median age at first event (years) | 55.21 | 53.70 | 55.95 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1497
- Matched controls
- 14970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K83
ICPC
Heart valve disease NOS
49.6
319.4
187
43
WX872
NOMESCO Finland
Intensive care
12.6
307.7
355
360
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
61.7
307.7
445
102
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
61.8
307.7
449
103
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
107.0
307.7
272
31
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
59.9
307.7
216
42
B01AA03
ATC
warfarin; systemic
11.8
307.7
751
1180
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
28.5
307.7
483
246
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
43.4
307.7
695
293
I35.0
ICD-10 Finland
Aortic (valve) stenosis
39.3
307.7
652
288
Q23.11
ICD-10 Finland
Bicuspid aortic valve
+∞
307.7
1497
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
18.0
307.7
544
459
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
51.4
307.7
564
174
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
10.9
307.7
985
2246
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
8.7
307.7
750
1552
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
44.6
301.6
181
46
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
5.6
238.7
705
2044
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
96.6
222.7
116
13
PD5BD
NOMESCO Finland
Extensive CT of aorta
25.3
219.5
157
69
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
190.9
560
1572
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.8
189.7
345
628
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
15.7
170.3
152
107
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
65.9
158.0
87
14
C07AB07
ATC
bisoprolol; oral
4.1
148.6
972
4696
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.6
147.6
266
474
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
135.5
128
*
PD5AD
NOMESCO Finland
CT of aorta
10.7
129.2
146
149
AB1
HP
AVR mechanical
51.6
119.7
69
14
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
191.2
119.4
123
7
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
108.0
951
5161
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
19.2
100.8
80
44
K84
ICPC
Heart disease other
8.9
100.0
130
159
B01AB05
ATC
enoxaparin; parenteral
3.1
92.2
609
2744
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
42.2
87.8
53
13
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
83.1
79
*
XF640, ,
NOMESCO Finland
8.9
80.9
104
125
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
75.7
72
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
16.7
75.6
64
40
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
101.4
70.6
77
8
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.1
69.7
378
1491
I97.0
ICD-10 Finland
Postcardiotomy syndrome
32.4
67.8
44
14
XF404
NOMESCO Finland
Ambulatory ECG
4.0
66.8
214
604
TFP20
NOMESCO Finland
Cardiodefibrillation
4.2
66.2
196
522
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
17.5
65.4
54
32
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
22.5
65.1
48
22
WW502
NOMESCO Finland
Autotransfusion
18.5
64.8
52
29
I35.8
ICD-10 Finland
Other aortic valve disorders
25.7
64.3
45
18
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
8.3
61.8
83
105
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
5.3
61.5
130
263
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
61.0
269
934
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
60.9
300
1112
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
22.1
57.9
43
20
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
22.7
57.2
42
19
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.8
56.8
134
298
XFE00
NOMESCO Finland
Epicardial ultrasonography
8.1
56.5
77
99
K78
ICPC
Atrial fibrillation/flutter
4.2
56.1
164
431
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
21.6
56.0
42
20
201
Kela drug reimbursment
Chronic cardiac insufficiency
4.8
55.6
134
303
XF402
NOMESCO Finland
ECG with work load test
3.3
54.8
233
788
C03CA01
ATC
furosemide; systemic
2.5
52.4
426
2035
I44.2
ICD-10 Finland
Atrioventricular block, complete
6.7
51.9
84
131
AN1
HP
Coronary angiography
3.3
51.7
219
738
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.7
48.4
93
172
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
16.2
47.9
41
26
C01BD01
ATC
amiodarone; systemic
5.7
45.9
87
159
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.2
44.1
190
644
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
43.2
474
2550
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
8.7
42.3
54
64
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
79.2
41.1
46
6
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
40.8
39
*
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
108.0
38.9
42
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.2
38.9
108
272
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.6
38.4
132
387
K99
ICPC
Cardiovascular disease other
5.8
37.9
71
128
AB2
HP
AVR bio, stent
133.4
36.9
39
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.1
36.7
169
594
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
5.5
35.6
70
132
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
4.3
35.3
93
225
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
184.3
34.9
36
*
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
47.9
34.8
42
9
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
34.8
275
1272
C03DA01
ATC
spironolactone; oral
2.7
34.7
206
830
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
34.7
715
4769
J01CA04
ATC
amoxicillin; systemic
2.5
33.9
1296
10746
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
334.2
33.0
33
*
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
32.4
31
*
C09AA05
ATC
ramipril; oral
2.1
32.1
390
2146
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
4.4
32.0
82
194
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
89.6
31.8
35
*
WX402
NOMESCO Finland
General anaesthesia
2.1
31.5
414
2344
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
31.4
30
*
AJ2
HP
Reconstruction of the ascending aorta
87.0
30.8
34
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.7
30.6
187
763
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
42.1
30.0
37
9
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
29.9
564
3606
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.2
29.3
81
203
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.6
29.3
101
296
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.0
28.7
136
484
R4110
NOMESCO Finland
Physiotherapy
2.0
28.6
453
2724
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
28.2
27
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
27.2
26
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
25.6
487
3087
FM2CE, ,
NOMESCO Finland
9.5
25.4
30
32
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
25.1
24
*
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
25.1
24
*
WZC30
NOMESCO Finland
Teaching
2.1
24.6
289
1555
I35
ICD-10 Finland
Nonrheumatic aortic valve disorders
42.2
23.7
29
7
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
30.6
22.8
30
10
WX892
NOMESCO Finland
Monitored bed care
2.5
22.1
142
591
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
25.5
21.8
30
12
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
18.7
21.8
33
18
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.4
21.4
78
237
W0X00, ,
SPAT
50.8
21.2
25
5
C10AA05
ATC
atorvastatin; oral
1.7
20.9
613
4346
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
22.7
20.4
29
13
AA1AD
NOMESCO Finland
CT of head and brain
1.8
19.6
406
2606
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
19.3
419
2723
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
17.0
19.2
30
18
C09CA01
ATC
losartan; oral
1.8
19.1
372
2342
250, ,
Kela drug reimbursment
4.5
19.0
46
104
21
HP
Aortic Valve Replacement (AVR)
34.8
18.9
24
7
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.2
18.8
51
126
31
HP
Congenital heart failure surgery
+∞
18.8
18
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
18.8
18
*
61
HP
Catheterization and pressure measurement of the left side of the heart
6.0
18.7
33
56
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.6
18.7
117
481
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
5.5
18.6
36
67
Z2221
NOMESCO Finland
Medical doctor
1.8
18.5
387
2486
PC1AD
NOMESCO Finland
CT of thoracic aorta
22.0
18.2
26
12
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
18.1
119
501
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.6
18.0
108
434
C01AA05
ATC
digoxin; systemic
2.9
17.6
86
311
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.6
17.5
28
43
R55
ICD-10 Finland
Syncope and collapse
2.2
17.3
163
801
G45.3
ICD-10 Finland
Amaurosis fugax
4.5
17.1
42
96
I50.1
ICD-10 Finland
Left ventricular failure
3.0
17.1
77
266
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
17.0
105
428
XF600
NOMESCO Finland
Bloodpressure measurement
2.5
17.0
110
459
K22
ICPC
Risk factor cardiovascular disease
2.6
16.9
99
394
C07AB02
ATC
metoprolol; systemic
1.9
16.8
235
1330
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
16.7
16
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
16.7
16
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
16.4
290
1767
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.9
16.2
76
269
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.6
16.0
91
357
K29
ICPC
Cardiovascular sympt/complt other
3.0
15.9
70
239
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.3
15.8
41
98
ZXE00
NOMESCO Finland
One hour or less
1.6
15.7
533
3852
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
15.6
15
*
Q23.1
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
15.6
15
*
FMC20
NOMESCO Finland
Suture of leaflet of aortic valve
+∞
15.6
15
*
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
20.3
15.1
22
11
TFP34
NOMESCO Finland
Electrophysiological investigation
3.0
14.9
65
221
N02BE01
ATC
paracetamol; systemic, rectal
1.8
14.8
1282
11459
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.9
14.8
32
66
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
14.6
14
*
5513
FHL
Coarctation resection, plastic or bypass
+∞
14.6
14
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
14.3
403
2773
C09AA04
ATC
perindopril; oral
2.7
14.1
77
296
207
Kela drug reimbursment
Chronic arrhythmias
1.9
14.1
195
1098
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
14.0
803
6466
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.4
13.9
100
438
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
13.9
102
451
R06.0
ICD-10 Finland
Dyspnoea
1.6
13.9
367
2482
I50.0
ICD-10 Finland
Congestive heart failure
2.5
13.8
85
347
Q23.9
ICD-10 Finland
Congenital malformation of aortic and mitral valves, unspecified
+∞
13.6
13
*
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
13.6
13
*
FM1AD
NOMESCO Finland
CT of heart
16.4
13.5
21
13
I71.1
ICD-10 Finland
Thoracic aortic aneurysm, ruptured
18.4
13.4
20
11
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
13.3
329
2186
GD1AD
NOMESCO Finland
Thorax CT examination
2.3
13.2
107
493
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
13.9
13.2
22
16
R50.9
ICD-10 Finland
Fever, unspecified
1.8
13.1
240
1469
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
9.8
12.7
25
26
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
4.5
12.6
30
67
GD1LA
NOMESCO Finland
GD
4.4
12.4
31
72
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.4
12.4
44
132
I38
ICD-10 Finland
Endocarditis, valve unspecified
18.2
12.1
18
10
C08CA01
ATC
amlodipine; oral
1.5
11.9
493
3673
I34.1
ICD-10 Finland
Mitral (valve) prolapse
3.0
11.7
50
168
C10AX09
ATC
ezetimibe; oral
1.7
11.7
260
1676
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
23.1
11.6
16
7
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
11.5
11
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
11.5
11
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
11.5
11
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
11.5
94
436
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.6
11.4
65
255
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
120.9
11.4
12
*
ZXD05
NOMESCO Finland
Urgent procedure
1.5
11.3
401
2884
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.3
276
1822
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
3.8
11.1
33
88
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
11.0
503
3811
FM1DE, ,
SPAT
12.0
10.8
19
16
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.1
10.8
111
562
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
10.8
525
4021
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
3.3
10.7
39
119
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
60.4
10.6
12
*
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
60.4
10.6
12
*
FCB40
NOMESCO Finland
Resection and reconstruction of aortic arch using tube graft
60.4
10.6
12
*
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
10.6
171
1006
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
4.5
10.5
25
56
FMC10
NOMESCO Finland
Reduction of leaflet of aortic valve
110.8
10.4
11
*
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
10.4
10
*
Z71.8
ICD-10 Finland
Other specified counselling
1.5
10.4
472
3563
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
12.1
10.3
18
15
211
HP
AVR mechanical
32.8
10.3
13
*
Z50.0
ICD-10 Finland
Cardiac rehabilitation
4.9
10.3
22
45
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
18.9
10.3
15
8
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
10.2
223
1427
FN1AD
NOMESCO Finland
CT of coronary arteries
3.2
10.1
40
129
I44.0
ICD-10 Finland
Atrioventricular block, first degree
4.0
10.1
28
71
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.7
10.0
52
195
I49.1
ICD-10 Finland
Atrial premature depolarization
2.6
10.0
59
236
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
9.9
298
2060
5253
FHL
Cardiac lung machine
10.7
9.8
18
17
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.5
9.8
60
245
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.5
9.8
59
239
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
55.4
9.7
11
*
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
4.0
9.6
27
69
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.9
9.5
43
150
Z01.2
ICD-10 Finland
Dental examination
1.4
9.4
676
5522
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
9.4
9
*
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
9.4
9
*
Q32.11
ICD-10 Finland
Congenital tracheo-esophageal fissure
+∞
9.4
9
*
7463D
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[BIKUSPINEN AORTALÄPPÄ]
+∞
9.4
9
*
C09CA06
ATC
candesartan; oral
1.5
9.1
322
2301
62
HP
Catheterization and pressure measurement of the right side of the heart
12.6
8.9
15
12
WX704
NOMESCO Finland
Intubation
1.9
8.9
116
640
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
8.7
613
4969
Q96.0
ICD-10 Finland
Karyotype 45,X
50.3
8.7
10
*
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.8
8.6
42
153
C07AA07
ATC
sotalol; systemic
2.8
8.5
42
154
PA1BD
NOMESCO Finland
Extensive CT of aortic arch and branches
27.7
8.5
11
*
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
27.7
8.5
11
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
20.1
8.5
12
6
FCA96
NOMESCO Finland
Other repair of ascending aorta
+∞
8.3
8
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
8.3
8
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
8.3
8
*
K80
ICPC
Cardiac arrhythmia NOS
1.9
8.3
110
609
XF620
NOMESCO Finland
Examination of circulation with color method
10.8
8.3
15
14
R04.0
ICD-10 Finland
Epistaxis
1.9
8.3
100
538
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.2
8.1
31
98
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.1
231
1573
I71.6
ICD-10 Finland
Thoracoabdominal aortic aneurysm, without mention of rupture
17.3
8.1
12
7
I48.3
ICD-10 Finland
Typical atrial flutter
3.8
7.8
23
61
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
7.7
182
1185
Q96.9
ICD-10 Finland
Turner syndrome, unspecified
45.2
7.7
9
*
FM1AT
NOMESCO Finland
Percutaneous implantation of aortic valve endoprosthesis
45.2
7.7
9
*
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
7.7
1141
12297
N02AX02
ATC
tramadol; systemic, rectal
1.4
7.6
569
4630
FWW96
NOMESCO Finland
Other reoperation on heart or major thoracic vessels
18.5
7.6
11
6
81
HP
Angiography of the heart and coronary arteries
2.2
7.6
64
302
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
4.1
7.5
20
49
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
4.1
7.5
20
49
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.5
979
8677
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.6
7.5
165
1056
A02BC02
ATC
pantoprazole; systemic
1.4
7.5
900
7876
SPAT1079
SPAT
Echocardiography
3.9
7.4
21
54
FM1EE, ,
SPAT
3.4
7.4
26
78
I71.01
ICD-10 Finland
Aneurysm of the descending aorta
13.4
7.4
12
9
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.4
437
3422
RD211, ,
NOMESCO Finland
2.2
7.4
60
279
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
7.4
136
832
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
7.3
7
*
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
7.3
7
*
ABX
HP
Other aortic valve operation
+∞
7.3
7
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.3
7.2
54
243
R00.2
ICD-10 Finland
Palpitations
1.8
7.1
104
594
I72.1
ICD-10 Finland
Aneurysm and dissection of artery of upper extremity
20.1
7.1
10
5
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
20.1
7.1
10
5
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.3
7.1
52
231
I47.2
ICD-10 Finland
Ventricular tachycardia
2.8
7.1
35
129
FM1CD
NOMESCO Finland
Very extensive CT of heart
8.8
7.0
14
16
SPAT1263
SPAT
Sampling
1.4
7.0
516
4178
5273
FHL
Repair with flap prosthesis or graft
40.2
6.8
8
*
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
40.2
6.8
8
*
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.3
6.8
17
40
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
16.8
6.7
10
6
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
22.6
6.7
9
*
3A422, ,
NOMESCO Finland
22.6
6.7
9
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
6.7
118
714
C08CA13
ATC
lercanidipine; oral
1.6
6.6
163
1072
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
6.5
80
434
AQ1
HP
Conventional electrophysiological examination
3.7
6.5
20
55
WX882
NOMESCO Finland
High dependency care
2.3
6.5
45
196
AP1
HP
Catheterization of the left side of the heart
3.2
6.4
24
75
474, ,
NOMESCO Finland
70.1
6.4
7
*
FMB10
NOMESCO Finland
Transannular expansion of aortic ostium
70.1
6.4
7
*
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.3
6.4
23
70
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.4
560
4638
J01DB01
ATC
cefalexin; oral
1.4
6.3
1169
10770
74679
ICD-8 Finland
Congenital anomalies of heart, Aliae malformationes valvulae aortae sive ventriculi sinistri
+∞
6.3
6
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
6.3
6
*
PD5DM
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
6.3
6
*
K73
ICPC
Congenital anomaly cardiovascular
+∞
6.3
6
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
6.3
6
*
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.8
6.2
86
484
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
7.1
6.2
14
20
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
2.7
6.2
31
115
A41.9
ICD-10 Finland
Sepsis, unspecified
2.2
6.1
48
220
M01AH05
ATC
etoricoxib; oral
0.8
6.1
660
7604
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1101
3440
9.32
307.65
4.4
3.2
931.58
1169.26
ng/l
1.01
1031
2903
661
2006
5.11
207.03
3.9
2.5
30.47
29.62
s
2.60
649
1959
466
1057
5.95
204.92
2.5
2.3
17.47
8.06
ug/l
9.22
454
961
1097
5733
4.42
150.20
58.4
12.5
1.87
1.21
inr
139.11
993
4755
348
834
5.13
139.49
3.2
3.0
163.95
175.01
ng/l
0.21
329
754
67
38
18.41
83.08
10.3
6.3
6.22
6.14
kpa
0.27
62
33
62
33
19.56
79.12
9.2
6.4
4.99
5.34
kpa
0.82
62
33
533
2406
2.89
77.98
5.1
3.8
1864.14
557.41
ng/l
6.49
482
1824
390
1487
3.19
77.05
3.6
4.9
283.65
245.55
u/l
5.48
377
1423
49
24
21.07
64.69
7.4
7.3
11.19
11.14
%
0.04
49
24
698
3905
2.48
63.02
2.7
2.3
336.34
271.81
u/l
0.83
673
3730
922
5920
2.45
60.25
3.3
2.9
—
—
estimate
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
158
390
4.41
58.82
9.0
3.1
0.33
0.33
iu/ml
0.08
97
202
579
3153
2.36
53.39
2.6
2.5
—
—
—
0
0
1075
7687
2.41
50.79
9.3
5.9
6.62
6.71
mmol/l
0.96
1046
7325
50
41
12.58
50.63
9.5
6.4
25.80
25.09
mmol/l
0.57
45
35
166
474
3.81
50.47
7.4
3.1
88.22
94.21
%
2.71
166
462
322
1419
2.62
46.22
16.7
10.3
97.25
95.84
%
4.01
313
1377
343
1561
2.55
46.04
16.6
9.8
5.17
5.13
kpa
0.49
336
1516
343
1561
2.55
46.04
16.6
9.8
14.16
12.47
kpa
5.20
335
1518
751
4770
2.15
45.50
4.1
3.6
70.83
68.28
ng/l
0.05
550
3301
340
1549
2.55
45.48
16.3
9.8
0.86
0.85
mmol/l
0.01
307
1302
960
6776
2.16
43.30
6.3
7.3
14.61
12.22
umol/l
5.29
921
6516
296
1297
2.60
42.70
8.2
9.4
8.02
9.15
mmol/l
2.52
289
1252
236
942
2.79
40.84
15.8
12.3
95.12
94.14
%
1.55
236
936
418
2244
2.20
37.47
4.7
4.6
0.83
0.82
mmol/l
1.82
403
2148
400
2143
2.18
35.82
2.6
2.7
13.01
13.98
umol/l
2.04
381
2016
1469
13024
7.84
35.66
28.1
17.8
139.41
139.71
mmol/l
5.97
1460
12800
1471
13062
8.26
35.52
28.0
17.9
4.01
3.98
mmol/l
4.79
1462
12812
543
3360
1.97
32.26
5.3
4.7
74.81
89.46
%
22.64
534
3306
371
2005
2.13
32.03
2.6
2.7
2.39
2.33
g/l
1.30
352
1874
195
803
2.64
31.35
22.8
12.9
15.67
16.31
%
2.62
190
777
346
1861
2.12
30.01
2.7
2.8
22.09
24.16
%
2.10
330
1750
229
1046
2.40
29.48
3.4
2.6
62.96
71.23
ml/min/173m2
2.12
85
431
193
815
2.57
29.41
18.4
7.5
24.69
24.51
mmol/l
0.34
187
783
256
1295
2.18
25.65
12.7
10.4
1.23
1.37
mmol/l
1.68
251
1270
1191
9887
2.00
25.51
8.2
8.5
76.37
81.34
u/l
4.00
1154
9468
186
826
2.43
25.31
5.0
4.5
120.96
132.35
g/l
8.28
179
805
1389
12291
2.80
24.94
19.9
14.4
84.60
85.53
ml/min/173m2
0.91
1325
11295
74
197
3.90
24.66
9.9
6.3
11.09
11.03
mg/l
0.04
66
184
769
5640
1.75
24.30
12.1
7.9
1.18
1.21
mmol/l
20.90
734
5268
832
6262
1.74
23.77
11.8
8.4
1.18
1.21
mmol/l
20.62
735
5478
1422
12888
3.06
21.47
21.2
15.2
34.39
24.23
mg/l
21.68
1281
10497
1475
13780
5.79
19.05
28.0
19.1
80.99
78.92
umol/l
1.56
1470
13652
130
558
2.46
18.93
1.9
1.9
1.24
1.52
g/l
2.49
88
490
642
4699
1.64
18.77
3.5
3.6
33.46
37.85
u/l
0.60
621
4448
210
1116
2.03
18.10
3.4
3.4
74.43
71.73
e9/l
0.43
155
813
83
291
2.96
17.96
1.5
1.6
—
—
—
0
0
333
2072
1.78
17.63
1.9
2.0
—
—
—
0
0
467
3203
1.67
17.30
2.5
2.4
3.09
2.77
mg/l
1.77
432
2771
241
1386
1.88
16.39
4.2
5.5
1.86
1.75
mmol/l
0.19
213
1188
1112
9524
1.65
15.60
4.5
4.3
10.79
10.49
mm/h
0.33
1056
8966
761
5973
1.56
15.54
3.4
3.1
131.63
145.13
ug/l
0.88
721
5631
766
6037
1.55
15.24
13.4
11.8
0.00
0.00
e9/l
0.02
666
4916
94
387
2.52
14.95
1.5
1.7
—
—
—
0
0
422
2917
1.62
14.74
2.9
1.9
1.39
1.12
mg/l
0.59
304
2234
117
538
2.27
14.55
3.1
2.0
1.65
2.17
ug/l
0.31
108
491
713
5599
1.52
13.98
5.6
5.7
36.12
36.20
g/l
0.13
682
5300
252
1568
1.73
12.99
1.8
1.9
—
—
—
0
0
238
1488
1.71
12.00
1.9
1.9
—
—
—
0
0
1334
12232
1.83
12.00
4.9
4.3
1.30
1.35
mmol/l
1.66
1279
11428
60
226
2.72
11.44
1.4
1.3
4.45
3.64
u/ml
0.11
31
88
1231
11091
1.62
11.25
26.8
18.7
13.53
13.50
%
0.50
1221
10975
224
1407
1.70
11.06
9.2
6.6
—
—
—
0
0
1483
14272
5.18
10.66
33.6
22.8
235.12
247.55
e9/l
12.94
1467
14015
278
1863
1.60
10.62
8.0
7.5
1.08
1.06
mmol/l
0.50
272
1757
1483
14277
5.14
10.55
33.4
22.7
90.58
90.58
fl
0.00
1474
14159
1444
13702
2.52
10.52
13.5
11.9
28.58
29.39
u/l
1.06
1414
13408
1483
14279
5.13
10.51
35.3
23.5
39.89
42.05
%
5.25
1474
14151
1483
14279
5.13
10.51
33.5
22.8
4.46
4.62
e12/l
26.36
1465
13981
1483
14282
5.10
10.44
33.9
23.0
133.37
139.32
g/l
37.05
1474
14162
1483
14282
5.10
10.44
33.5
22.9
6.81
6.70
e9/l
1.30
1464
13978
82
380
2.22
10.05
1.5
1.9
—
—
—
0
0
1277
11689
1.63
10.03
5.3
4.8
1.91
1.89
mu/l
0.21
1207
10884
1323
12245
1.69
9.63
4.9
4.9
5.90
5.96
mmol/l
0.83
1239
11395
56
225
2.55
9.44
1.4
1.3
7.03
5.31
u/ml
0.28
35
112
14
8
17.65
9.40
14.8
4.4
100.57
104.25
g/l
—
14
8
537
4217
1.43
9.36
3.6
3.4
275.13
70.09
e6/l
0.42
419
3195
1085
9646
1.45
9.25
4.4
3.9
15.02
14.72
pmol/l
3.49
1014
8914
1375
12895
1.81
9.13
5.7
5.0
4.44
4.61
mmol/l
9.32
1330
12206
384
2855
1.46
8.90
2.9
2.7
4.08
4.73
e6/l
0.47
350
2603
1381
13005
1.80
8.52
6.5
5.6
2.61
2.74
mmol/l
7.24
1336
12254
44
167
2.68
8.34
2.8
2.4
32.61
33.07
pg
0.37
44
167
75
363
2.12
8.29
1.5
1.9
—
—
—
0
0
1366
12845
1.73
8.18
5.6
4.9
1.38
1.38
mmol/l
0.16
1317
12081
463
3631
1.40
7.83
3.5
3.3
0.42
0.41
e6/l
0.06
353
2626
879
7636
1.37
7.83
9.9
10.5
4.12
4.09
e9/l
0.13
775
6615
1302
12145
1.55
7.51
5.9
6.1
38.13
39.08
mmol/mol
4.20
1248
11532
67
326
2.10
7.34
1.4
1.6
—
—
—
0
0
896
7869
1.35
7.08
4.4
4.2
1354.07
641.73
e6/l
0.28
15
114
124
760
1.69
6.67
1.7
1.6
—
—
—
0
0
30
108
2.81
6.34
1.4
1.4
273.63
411.55
u/l
0.69
30
103
425
3391
1.35
6.21
1.6
1.7
19.91
19.77
nmol/l
0.07
375
2914
55
266
2.11
6.16
1.3
1.6
—
—
—
0
0
42
191
2.23
5.51
1.4
1.8
—
—
—
0
0
503
4172
1.31
5.50
2.9
2.8
60.08
79.95
u/l
0.52
462
3922
27
100
2.73
5.45
6.2
3.6
13.32
12.89
index
0.07
19
73
38
167
2.31
5.40
2.3
3.1
0.83
0.84
nmol/l
0.05
30
129
54
277
1.98
5.21
1.3
1.6
—
—
—
0
0
41
192
2.17
5.03
1.5
1.9
—
—
—
0
0
48
242
2.02
4.88
1.4
2.0
—
—
—
0
0
966
8800
1.28
4.74
3.0
3.1
—
—
—
0
0
174
1249
1.44
4.69
3.2
3.3
—
—
—
0
0
101
650
1.59
4.55
1.4
1.4
—
—
—
0
0
43
215
2.03
4.49
1.4
1.6
—
—
—
0
0
69
407
1.73
4.35
1.4
1.9
—
—
—
0
0
290
2301
1.32
4.23
3.3
3.0
0.77
0.92
e6/l
0.38
172
1195
28
123
2.30
4.05
1.2
1.4
6.24
6.35
mmol/l
0.12
28
115
46
249
1.87
3.87
1.4
1.3
—
—
—
0
0
46
249
1.87
3.87
1.4
1.3
—
—
—
0
0
44
241
1.85
3.59
1.2
1.1
—
1.38
—
0
14
72
457
1.60
3.50
2.3
2.8
—
—
—
0
0
28
132
2.14
3.46
1.6
1.4
2658.00
1842.56
e6/l
0.43
21
84
69
436
1.61
3.42
1.6
2.1
—
—
—
0
0
104
723
1.47
3.36
3.8
3.6
4.52
4.66
pmol/l
0.65
94
655
745
6759
1.20
3.16
3.9
3.5
15.05
3.81
estimate
0.52
166
1389
49
290
1.71
3.13
1.5
1.6
—
—
—
0
0
47
275
1.73
3.13
2.7
4.4
—
1919.21
—
0
24
737
6691
1.20
3.07
3.9
3.5
0.00
0.00
estimate
0.50
160
1390
18
74
2.45
3.05
1.3
1.2
—
—
—
0
0
51
308
1.68
3.04
1.9
1.8
—
—
—
0
0
24
113
2.14
3.01
1.5
1.4
97990.00
23164.28
e6/l
0.79
13
58
11
31
3.57
2.99
1.3
1.4
84.83
90.15
%
—
6
13
19
81
2.36
2.99
1.4
2.1
—
—
—
0
0
32
170
1.90
2.91
1.2
1.4
414.16
337.76
pmol/l
0.26
26
152
743
6787
1.19
2.79
3.9
3.6
0.00
0.25
estimate
0.53
155
1272
421
3655
1.21
2.77
4.1
3.7
0.52
0.01
estimate
0.49
143
1286
571
5106
1.19
2.72
3.8
3.4
0.01
0.02
estimate
0.01
136
1172
14
55
2.56
2.62
1.0
1.1
—
—
—
0
0
118
881
1.37
2.61
1.9
1.7
—
—
—
0
0
9
25
3.62
2.57
1.3
1.4
—
—
—
0
0
55
357
1.56
2.51
6.1
7.7
2154.33
360.77
iu/ml
—
6
53
12
45
2.68
2.45
1.0
1.2
71.00
94.48
%
—
7
27
21
103
2.05
2.42
1.4
1.7
—
—
—
0
0
198
1615
1.26
2.33
2.8
3.3
9.00
8.13
umol/l
0.25
179
1446
120
916
1.34
2.33
4.0
4.3
1.22
1.22
mmol/l
0.04
107
801
406
3566
1.19
2.31
2.9
2.9
359.75
352.82
umol/l
0.75
379
3213
254
2133
1.23
2.31
3.3
3.2
1.73
1.55
e6/l
0.12
134
1026
591
5357
1.17
2.30
2.0
2.0
95.36
95.72
pmol/l
0.07
338
2969
71
500
1.44
2.23
3.0
3.1
1.02
1.02
ratio
0.20
62
471
17
82
2.09
2.07
1.4
1.7
—
—
—
0
0
17
82
2.09
2.07
1.4
1.8
—
—
—
0
0
6
15
4.01
2.04
1.0
1.7
—
—
—
0
0
627
5752
1.15
2.02
1.9
1.9
1.44
1.43
mmol/l
0.12
521
4930
59
410
1.46
2.01
2.1
2.6
0.94
1.09
g/l
0.12
52
370
18
91
1.99
1.95
1.3
1.7
—
—
—
0
0
57
397
1.45
1.93
3.6
3.7
106.60
39.65
mg/l
0.51
47
333
11
45
2.46
1.93
1.0
1.6
57.17
93.44
%
—
6
27
57
398
1.45
1.91
3.6
3.7
89.23
62.56
mg/l
0.30
46
332
20
106
1.90
1.91
5.8
2.3
28.86
37.35
mg/l
0.51
14
76
48
324
1.50
1.90
5.0
3.3
7.97
2.00
index
0.77
34
182
162
1330
1.24
1.84
2.7
2.6
0.20
0.22
g/l
1.94
156
1251
21
115
1.84
1.83
1.0
1.1
—
—
—
0
0
178
2119
0.82
1.75
2.0
1.9
1.44
1.50
%
0.45
157
1879
50
347
1.46
1.75
1.7
1.6
116.10
141.28
au/ml
0.63
15
111
213
1816
1.20
1.68
1.6
1.7
1246.51
1172.06
nmol/l
0.61
173
1401
14
69
2.04
1.64
1.9
2.4
237.57
194.13
u/l
1.37
14
69
10
42
2.39
1.61
2.7
1.7
40.17
41.74
g/l
—
10
42
16
84
1.91
1.60
4.1
2.9
969.88
1041.13
u/ml
0.04
16
84
51
364
1.42
1.57
2.1
2.5
0.02
0.01
g/l
0.15
46
335
28
176
1.60
1.55
1.1
1.5
0.55
0.60
nmol/l
0.30
28
169
31
468
0.66
1.55
1.2
1.3
131.55
221.79
miu/ml
1.36
14
210
141
1166
1.23
1.53
3.4
2.8
11.30
10.59
g/l
1.06
133
1091
52
375
1.40
1.52
1.4
1.4
279.17
258.26
u/ml
0.21
39
222
19
108
1.77
1.51
1.3
3.0
—
—
—
0
0
456
4165
1.14
1.49
3.2
3.6
2.34
2.35
mmol/l
0.92
416
3833
49
354
1.40
1.43
1.6
2.5
0.00
0.00
g/l
-0.00
43
312
21
126
1.68
1.40
1.1
1.1
—
—
—
0
0
50
364
1.39
1.40
1.2
1.1
—
—
—
0
0
12
61
1.98
1.33
1.1
1.2
—
—
—
0
0
71
552
1.30
1.31
1.9
1.7
11.26
7.03
iu/ml
0.63
23
130
10
48
2.09
1.28
1.4
1.6
—
—
—
0
0
41
563
0.72
1.27
1.6
1.6
9.22
6.94
u/l
0.53
33
440
49
363
1.36
1.26
3.4
3.4
3.31
3.37
ratio
0.01
24
200
49
365
1.35
1.22
1.2
1.1
—
—
—
0
0
18
108
1.67
1.22
1.1
1.1
—
—
—
0
0
120
1003
1.21
1.21
1.6
1.5
—
—
—
0
0
109
1306
0.82
1.19
1.8
1.8
3.31
3.51
mmol/l
1.06
80
931
18
109
1.66
1.19
1.1
1.1
—
—
—
0
0
18
109
1.66
1.19
1.1
1.1
—
—
—
0
0
47
351
1.35
1.16
1.3
1.3
—
—
—
0
0
10
50
2.01
1.16
2.3
2.5
—
—
—
0
0
293
2646
1.13
1.14
1.6
1.6
—
—
—
0
0
17
103
1.66
1.13
1.6
1.6
3.26
4.00
mg/l
0.74
17
98
18
111
1.63
1.12
1.3
1.9
—
—
—
0
0
18
111
1.63
1.12
1.3
1.9
—
—
—
0
0
18
111
1.63
1.12
1.3
1.9
—
—
—
0
0
21
135
1.56
1.11
1.4
1.5
75.81
56.06
%
1.96
16
87
63
496
1.28
1.09
1.8
1.7
—
—
—
0
0
57
443
1.30
1.09
1.2
1.3
—
—
—
0
0
12
66
1.82
1.09
1.0
1.2
183.58
227.16
iu/ml
0.29
12
66
36
261
1.39
1.08
1.5
1.4
—
—
—
0
0
67
533
1.27
1.08
1.2
1.4
—
—
—
0
0
505
4726
1.10
1.04
4.6
4.0
23.04
21.39
%
1.19
241
2078
8
147
0.54
1.04
1.1
1.0
—
—
—
0
0
9
47
1.92
1.02
1.1
1.1
—
—
—
0
0
106
895
1.20
1.00
7.2
4.6
2.09
1.47
mmol/l
1.54
82
672
7
35
2.00
1.00
1.1
1.2
100.00
89.51
%
—
7
35
7
132
0.53
0.99
13.4
16.9
680.43
800.65
nmol/l
—
7
127
64
513
1.26
0.99
1.3
1.2
0.31
1.06
u/ml
—
9
32
154
1757
0.86
0.98
2.1
2.1
3.56
3.71
ratio
0.82
127
1387
43
328
1.32
0.96
2.0
2.4
129.76
132.54
g/l
0.32
33
259
251
2277
1.12
0.92
2.1
3.1
2.43
2.44
mmol/l
0.68
216
2060
15
232
0.64
0.92
1.1
1.4
—
—
—
0
0
11
63
1.75
0.90
3.5
2.8
19.04
150.26
ug/l
0.51
11
55
30
219
1.38
0.89
1.2
1.2
—
—
—
0
0
26
185
1.41
0.89
1.2
1.4
62.38
148.21
pmol/l
0.80
26
180
51
404
1.27
0.88
1.5
2.6
16121.69
5680.51
u/l
0.61
15
160
18
119
1.52
0.88
2.8
2.7
1.19
1.19
mmol/l
0.02
18
119
16
103
1.56
0.87
1.1
1.1
—
—
—
0
0
42
325
1.30
0.87
1.7
1.6
12622.43
13617.15
e6/l
0.09
28
233
60
486
1.24
0.87
1.6
1.7
11.57
16.98
u/ml
0.59
13
125
10
168
0.59
0.87
1.2
1.1
—
—
—
0
0
13
80
1.63
0.84
1.6
2.1
0.40
1.44
u/field
—
5
48
50
398
1.27
0.84
1.3
1.5
265.08
281.22
ug/g
0.17
25
246
98
838
1.18
0.83
1.2
1.2
70.75
154.08
u/ml
2.58
41
320
10
57
1.76
0.83
2.7
5.1
—
—
—
0
0
12
73
1.65
0.81
1.1
1.1
—
—
—
0
0
18
122
1.48
0.80
2.8
2.6
3.96
4.04
mmol/l
0.64
18
122
18
122
1.48
0.80
2.8
2.6
105.72
105.29
mmol/l
0.20
18
122
20
139
1.44
0.79
1.5
2.1
—
—
—
0
0
25
182
1.38
0.78
1.4
1.2
—
23.33
—
0
6
398
3732
1.09
0.77
3.2
3.0
4.10
0.04
estimate
0.79
122
1114
327
3040
1.10
0.77
4.2
3.5
1.02
1.02
kg/l
0.99
225
1995
105
912
1.16
0.76
4.8
5.0
92.58
86.04
ng/l
0.28
97
833
5
25
2.00
0.72
1.4
1.0
—
—
—
0
0
132
1484
0.88
0.72
4.7
4.7
31.51
30.89
%
0.25
102
1015
22
159
1.39
0.72
1.5
2.0
—
—
—
0
0
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
14
92
1.53
0.72
1.1
1.2
—
—
—
0
0
10
60
1.67
0.72
1.2
1.2
128.15
191.84
mmol/24h
—
10
60
615
5886
1.08
0.72
4.8
4.9
2.20
2.23
ug/l
0.05
555
5396
12
76
1.58
0.71
1.3
1.6
17.20
27.72
umol/l
1.56
12
71
22
160
1.38
0.70
1.6
1.3
—
—
—
0
0
7
41
1.71
0.70
1.6
1.0
—
—
—
0
0
147
1317
1.13
0.70
2.3
2.8
33.80
76.33
u/l
0.62
123
1132
42
338
1.25
0.68
1.4
1.4
—
—
—
0
0
17
119
1.43
0.67
1.3
1.2
417006.33
77231.45
e6/l
0.45
12
84
5
95
0.52
0.66
1.0
1.0
258.00
241.46
ng/l
—
5
67
23
302
0.76
0.62
2.7
2.5
81.31
98.48
ug/min
0.12
18
174
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
449
4278
1.07
0.58
3.9
4.3
7.07
8.99
mg/mmol
0.62
298
2809
29
228
1.28
0.58
5.6
4.1
7.26
8.59
pmol/l
0.47
29
228
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
6
35
1.72
0.57
1.2
1.4
0.50
0.52
e9/l
—
6
35
13
184
0.70
0.57
3.9
3.3
21.54
21.54
nmol/l
0.00
13
176
80
701
1.15
0.56
1.2
1.1
3.10
0.74
u/ml
—
5
5
36
293
1.23
0.55
1.3
1.2
23.42
47.76
u/ml
—
5
27
109
1215
0.89
0.55
3.9
4.6
3.09
22.45
ug/l
2.06
91
1006
40
332
1.21
0.52
2.1
1.9
2.71
4.29
iu/l
1.51
18
136
9
63
1.43
0.52
1.1
1.3
—
51.25
—
0
8
15
202
0.74
0.50
1.7
1.6
22.56
30.28
ng/l
0.48
15
202
120
1320
0.90
0.50
2.2
2.3
361.61
366.80
nmol/l
0.11
108
1249
491
4720
1.06
0.48
3.4
3.7
8.05
8.42
mmol/l
0.90
426
4079
11
155
0.71
0.48
1.5
1.5
—
—
—
0
0
7
46
1.52
0.48
5.1
2.9
0.61
0.59
mmol/l
—
7
46
377
3599
1.06
0.47
3.1
3.0
0.73
0.70
ug/l
0.31
223
2147
10
69
1.45
0.44
1.0
1.3
3.60
5.73
umol/l
—
10
58
56
489
1.15
0.44
3.4
2.9
24.22
24.78
mmol/l
0.57
56
484
49
564
0.86
0.43
1.6
1.5
30.50
21.80
iu/l
0.96
43
456
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
93
0.64
0.42
1.2
1.1
—
—
—
0
0
13
96
1.36
0.41
1.1
1.1
104.69
109.57
pmol/l
0.16
13
96
5
33
1.52
0.41
1.4
1.6
—
—
—
0
0
5
34
1.47
0.40
1.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
28
335
0.83
0.39
1.7
1.6
5.14
43.00
e6/l
1.22
21
238
7
106
0.66
0.39
1.0
1.0
—
—
—
0
0
9
66
1.37
0.38
1.6
1.3
—
—
—
0
0
9
66
1.37
0.38
1.6
1.3
—
—
—
0
0
9
67
1.35
0.38
1.8
1.7
123.33
111.03
ng/l
—
9
67
971
9550
1.05
0.37
3.5
3.6
47.79
51.84
u/l
1.10
921
9117
255
2429
1.06
0.36
1.6
1.7
62559665.28
32368974.58
pmol/l
0.20
211
2073
12
155
0.77
0.33
1.6
1.5
—
—
—
0
0
79
722
1.10
0.32
1.0
1.1
—
—
—
0
0
20
164
1.22
0.32
1.2
1.4
145.41
221.66
pmol/l
0.71
20
164
12
154
0.78
0.32
1.5
1.4
—
—
—
0
0
24
284
0.84
0.32
1.4
1.4
—
—
—
0
0
21
174
1.21
0.31
1.2
1.1
—
—
—
0
0
7
96
0.73
0.31
1.1
1.1
—
—
—
0
0
7
53
1.32
0.31
1.1
1.4
—
—
—
0
0
7
53
1.32
0.31
1.1
1.4
—
—
—
0
0
53
476
1.12
0.30
1.5
1.5
12.42
0.16
iu/ml
—
10
73
93
862
1.08
0.29
1.2
1.3
19.36
53.24
au/ml
—
7
62
184
1935
0.94
0.29
2.2
2.5
13.44
13.93
nmol/l
0.41
168
1788
34
387
0.88
0.29
1.5
1.6
497.09
538.32
mg/l
0.51
34
370
32
279
1.15
0.28
1.1
1.1
8.65
18.15
au/ml
1.08
11
77
19
227
0.83
0.28
1.1
1.1
0.27
0.33
u/ml
—
8
87
8
63
1.27
0.27
1.0
1.4
144.13
442.89
u/l
—
8
57
9
119
0.75
0.27
1.2
1.2
—
—
—
0
0
18
215
0.84
0.27
1.0
1.1
1.28
2.57
eliau/ml
—
9
104
15
122
1.23
0.27
1.5
1.3
6.09
2.53
u/ml
—
8
69
17
204
0.83
0.27
2.7
3.9
1.79
1.54
%
0.12
17
189
56
614
0.91
0.26
1.1
1.1
0.66
0.68
ratio
—
9
66
74
800
0.92
0.26
2.8
2.3
—
—
—
0
0
331
3207
1.04
0.25
1.3
1.4
1.80
1.86
u/ml
0.04
96
904
45
406
1.11
0.25
1.2
1.1
3.75
3.36
—
8
66
12
147
0.81
0.23
1.6
1.5
—
—
—
0
0
11
136
0.81
0.23
3.5
4.4
—
—
—
0
0
12
97
1.24
0.23
1.1
1.2
—
—
—
0
0
11
88
1.25
0.22
1.1
1.2
—
—
—
0
0
12
146
0.82
0.22
1.6
1.5
—
—
—
0
0
12
146
0.82
0.22
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
7.9
—
—
—
0
0
0
12
0.00
0.21
0.0
5.8
—
—
—
0
0
28
314
0.89
0.21
1.0
1.1
0.93
1.01
u/ml
0.03
15
161
6
48
1.25
0.20
1.2
1.1
45.38
42.00
u/ml
—
6
48
69
645
1.07
0.20
1.4
1.3
—
—
—
0
0
23
202
1.14
0.20
1.9
2.2
—
1884.44
—
0
9
26
292
0.89
0.20
1.3
1.2
—
—
—
0
0
12
99
1.21
0.19
1.1
1.2
—
—
—
0
0
29
322
0.90
0.19
1.1
1.1
9.09
6.46
u/ml
0.24
17
194
166
1722
0.96
0.18
2.2
2.2
—
—
—
0
0
98
932
1.06
0.18
2.3
2.4
17.54
18.29
au/ml
0.06
14
93
14
119
1.18
0.17
1.7
1.3
2.45
2.05
mmol/l
0.86
14
110
227
2338
0.97
0.17
1.3
1.3
32.59
29.86
iu/ml
0.13
69
683
207
2134
0.97
0.17
1.3
1.3
6.47
11.57
u/ml
0.73
80
856
5
69
0.72
0.17
1.2
1.3
—
—
—
0
0
31
340
0.91
0.16
1.6
1.7
841.73
1434.54
e6/l
0.30
26
256
5
70
0.71
0.16
4.6
4.2
1.75
1.26
ug/l
—
5
65
51
545
0.93
0.16
2.3
1.8
3.39
4.39
mg/l
0.53
37
410
26
287
0.90
0.16
1.6
1.5
—
—
—
0
0
298
2914
1.03
0.15
1.8
1.6
2.41
2.50
g/l
0.36
209
1838
9
81
1.11
0.15
2.9
2.3
—
—
—
0
0
9
81
1.11
0.15
2.9
2.3
—
—
—
0
0
66
625
1.06
0.14
2.3
2.1
35.55
40.35
u/l
0.90
58
565
61
645
0.94
0.14
1.2
1.2
1.38
1.47
g/l
2.45
61
645
26
237
1.10
0.14
1.0
1.1
1.54
1.48
g/l
0.30
26
219
9
107
0.84
0.13
1.1
1.1
334.33
294.39
mg/l
—
9
95
155
1592
0.97
0.11
2.1
2.1
—
—
—
0
0
65
678
0.96
0.10
2.7
2.3
—
—
—
0
0
32
341
0.94
0.10
1.2
1.6
3.49
3.75
mmol/l
1.47
32
323
5
47
1.06
0.09
1.4
1.3
—
—
—
0
0
11
98
1.12
0.07
2.1
1.6
—
—
—
0
0
30
317
0.95
0.07
1.1
1.1
2.64
1.85
u/ml
0.14
16
179
28
264
1.06
0.07
1.2
1.3
14.57
44.66
u/l
1.73
23
225
8
76
1.05
0.07
1.1
1.0
1891.50
1436.87
miu/ml
—
8
76
8
90
0.89
0.06
2.1
1.6
—
—
—
0
0
8
95
0.84
0.06
1.0
1.5
76.13
80.07
umol/l
—
8
95
183
1804
1.02
0.06
2.6
2.9
129.49
135.09
ug/g
0.08
149
1488
27
257
1.05
0.05
1.3
1.6
—
—
—
0
0
19
202
0.94
0.05
1.1
1.1
—
—
—
0
0
15
161
0.93
0.05
2.1
1.4
—
—
—
0
0
11
120
0.92
0.05
2.4
2.8
—
—
—
0
0
15
140
1.07
0.04
1.1
1.3
—
—
—
0
0
16
170
0.94
0.04
2.1
1.8
—
—
—
0
0
17
180
0.94
0.04
1.3
1.5
0.34
0.30
nmol/l
—
10
137
10
109
0.92
0.04
2.2
1.5
—
—
—
0
0
37
359
1.03
0.03
1.2
1.1
3.12
3.25
u/ml
0.02
25
216
13
138
0.94
0.02
1.0
1.1
—
—
—
0
0
15
142
1.06
0.02
1.1
1.2
12.60
17.06
u/ml
—
7
55
13
123
1.06
0.01
1.7
2.3
23.35
16.92
mg/l
—
8
54
565
5638
1.00
0.01
2.4
2.5
76.92
74.52
nmol/l
1.10
519
5170
23
223
1.03
0.01
1.1
1.1
2.44
2.27
—
5
44
76
768
0.99
0.01
2.0
1.8
0.30
0.33
mg/l
0.20
38
417
13
124
1.05
0.00
1.7
2.0
—
—
—
0
0
20
202
0.99
0.00
1.2
1.3
—
—
—
0
0
26
262
0.99
0.00
1.1
1.1
0.85
3.49
u/ml
2.36
11
139
13
129
1.01
0.00
1.2
1.1
—
79.00
—
0
6
14
139
1.01
0.00
1.7
1.6
66.74
49.95
ug/l
0.70
14
139
20
201
0.99
0.00
1.7
1.7
—
—
—
0
0
127
1268
1.00
0.00
1.5
1.5
—
—
—
0
0
12
117
1.03
0.00
1.1
1.7
—
—
—
0
0
17
167
1.02
0.00
1.1
1.3
—
—
—
0
0
19
187
1.02
0.00
1.2
1.3
—
—
—
0
0
39
385
1.01
0.00
1.3
1.3
—
—
—
0
0
5
53
0.94
0.00
1.4
1.6
—
—
—
0
0
7
74
0.95
-0.00
1.3
1.2
5.57
8.68
mm/h
—
7
74
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
0.50
—
0
8
0
8
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.01
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
9.0
6.2
13.50
8.93
%
—
6
68
7
70
1.00
-0.00
1.4
3.2
1.50
1.21
%
—
7
70
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_BICUSP_AORTIC_VALVE – Bicuspidal aortic valve syndrome
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).