Left ventricular outflow tract obstruction, narrow definition

Q17_LVOTO_NARROW

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
  • Hospital discharge: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
  • Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Hospital discharge: excluded ICD-9 758|7595|75683
  • Cause of death: ICD-10 Q23, Q24.4, Q25.1, Q25.20, Q25.3, Q25.40
  • Cause of death: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B
  • Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875
  • Cause of death: excluded ICD-9 758|7595|75683

2 out of 7 registries used, show all original rules.

2157

4. Check minimum number of events

None

2157

5. Include endpoints

None

2157

6. Filter based on genotype QC (FinnGen only)

1931

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Similar endpoints

List of similar endpoints to Left ventricular outflow tract obstruction, narrow definition based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14391 5274 9068
Only index persons 11312 4077 7235
Unadjusted period prevalence (%)
Whole population 0.22 0.15 0.25
Only index persons 0.23 0.15 0.28
Median age at first event (years)
Whole population 18.56 15.60 20.08
Only index persons 29.81 26.79 31.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1931 697 1234
Unadjusted period prevalence (%) 0.45 0.25 0.57
Median age at first event (years) 50.10 45.73 52.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2024
Matched controls
20236
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
36.9
322.5
203
61
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
38.1
307.7
605
224
K83
ICPC
Heart valve disease NOS
46.9
307.7
218
52
Q23.11
ICD-10 Finland
Bicuspid aortic valve
16384.0
307.7
1497
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.0
307.7
1012
2033
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
35.0
307.7
807
376
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
88.6
307.7
315
42
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
307.7
346
*
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
51.8
307.7
508
130
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
51.7
307.7
234
51
B01AA03
ATC
warfarin; systemic
11.5
307.7
982
1530
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
24.9
307.7
635
365
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
16.4
307.7
722
661
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
10.0
307.7
1286
3003
I35.0
ICD-10 Finland
Aortic (valve) stenosis
32.0
307.7
746
363
WX872
NOMESCO Finland
Intensive care
11.4
307.7
421
456
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
53.2
307.7
530
134
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
5.3
285.8
862
2501
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
118.5
261.3
133
12
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.1
258.9
751
2087
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.8
255.5
465
846
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
87.5
248.5
131
16
PD5BD
NOMESCO Finland
Extensive CT of aorta
21.0
232.8
179
93
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.7
220.0
396
707
201
Kela drug reimbursment
Chronic cardiac insufficiency
8.3
207.6
297
412
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
15.3
207.1
187
134
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
84.3
196.2
104
13
C07AB07
ATC
bisoprolol; oral
3.7
177.1
1217
5905
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
53.6
169.7
97
19
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
149.2
1263
6721
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
146.7
139
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
7.2
146.0
230
352
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
11.0
140.5
155
152
PD5AD
NOMESCO Finland
CT of aorta
9.5
138.0
170
194
XF404
NOMESCO Finland
Ambulatory ECG
4.9
137.4
346
822
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
132.8
126
*
AB1
HP
AVR mechanical
39.1
128.6
79
21
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
34.8
121.4
77
23
XF640, ,
NOMESCO Finland
9.4
119.9
148
169
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
18.6
119.6
96
54
C03CA01
ATC
furosemide; systemic
3.2
118.8
654
2640
B01AB05
ATC
enoxaparin; parenteral
3.0
118.2
781
3494
XFE00
NOMESCO Finland
Epicardial ultrasonography
10.3
117.1
134
138
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
56.8
116.8
66
12
TPH07
NOMESCO Finland
Cathetrisation of artery
3.8
115.5
412
1262
XF402
NOMESCO Finland
ECG with work load test
4.1
115.3
362
1013
61
HP
Catheterization and pressure measurement of the left side of the heart
15.0
114.9
103
72
K84
ICPC
Heart disease other
8.3
114.6
157
204
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
28.5
114.1
77
28
ZXE20
NOMESCO Finland
More than three and less than five hours
3.6
113.3
454
1502
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
28.8
111.5
75
27
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
1105.5
108.4
105
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.6
107.7
220
433
FM2CE, ,
NOMESCO Finland
9.3
101.5
125
142
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
16.6
101.4
86
54
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
37.9
95.3
59
16
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.1
94.2
490
1884
TFP20
NOMESCO Finland
Cardiodefibrillation
4.4
93.8
257
645
XF400
NOMESCO Finland
ECG with 12 standard connections
3.1
92.1
482
1857
C03DA01
ATC
spironolactone; oral
3.6
90.2
344
1091
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
30.3
89.3
59
20
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
11.6
88.7
93
84
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
20.1
88.0
68
35
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
87.1
83
*
Q21.10
ICD-10 Finland
Persistent ostium secundum
12.9
84.1
82
66
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
22.0
83.5
62
29
C01AA05
ATC
digoxin; systemic
4.9
83.4
195
430
I44.2
ICD-10 Finland
Atrioventricular block, complete
7.6
83.2
121
168
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
24.4
80.0
57
24
XF622
NOMESCO Finland
Measurement of minute volume of heart
26.9
79.9
55
21
Q25.0
ICD-10 Finland
Patent ductus arteriosus
17.6
79.3
65
38
62
HP
Catheterization and pressure measurement of the right side of the heart
28.6
78.7
53
19
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
14.9
76.1
68
47
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
74.9
695
3536
I35.8
ICD-10 Finland
Other aortic valve disorders
25.4
74.0
52
21
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
32.0
72.3
47
15
WW502
NOMESCO Finland
Autotransfusion
18.3
70.8
57
32
C01BD01
ATC
amiodarone; systemic
6.2
70.7
125
213
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
4.2
70.4
198
504
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
14.4
69.2
63
45
FCA70
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of biological valve prosthesis and tube graft
30.7
68.3
45
15
I50.9
ICD-10 Finland
Heart failure, unspecified
3.3
67.0
289
981
I97.0
ICD-10 Finland
Postcardiotomy syndrome
24.0
65.6
47
20
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
64.9
62
*
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
17.8
63.7
52
30
XF600
NOMESCO Finland
Bloodpressure measurement
3.5
63.4
242
760
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
16.3
63.4
54
34
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
5.0
63.1
142
302
AN1
HP
Coronary angiography
3.2
62.2
270
918
31
HP
Congenital heart failure surgery
99.0
61.2
67
7
K78
ICPC
Atrial fibrillation/flutter
3.9
61.0
196
548
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
5.1
58.8
129
268
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
58.6
56
*
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
58.6
56
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
4.4
58.1
155
378
K99
ICPC
Cardiovascular disease other
6.6
57.5
95
151
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.9
57.5
106
188
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
57.1
828
4956
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.1
52.5
249
889
5253
FHL
Cardiac lung machine
15.8
52.1
45
29
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.2
51.2
107
213
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
50.2
48
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
17.4
49.8
41
24
WX402
NOMESCO Finland
General anaesthesia
2.2
49.3
591
3252
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.0
48.9
61
70
R4110
NOMESCO Finland
Physiotherapy
2.1
48.2
650
3734
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.1
48.2
226
800
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
69.2
47.3
54
8
Z2221
NOMESCO Finland
Medical doctor
2.1
47.1
610
3448
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
47.1
45
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
61.6
46.5
54
9
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.5
45.6
115
268
C09AA05
ATC
ramipril; oral
2.2
45.1
500
2655
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
73.0
44.2
50
7
WX892
NOMESCO Finland
Monitored bed care
2.9
43.1
221
821
AB2
HP
AVR bio, stent
96.2
42.9
47
5
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
15.7
42.6
37
24
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
41.8
40
*
I71.00
ICD-10 Finland
Dissecting aneurysm of aorta (ruptured) [any part]
16.2
40.9
35
22
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
38.7
37
*
J01CA04
ATC
amoxicillin; systemic
2.3
37.7
1752
14849
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.7
37.4
123
348
WZC30
NOMESCO Finland
Teaching
2.2
36.7
385
1983
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
4.4
36.4
94
223
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
6.0
36.1
64
109
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.1
35.5
62
104
C07AB02
ATC
metoprolol; systemic
2.2
35.4
345
1724
Z94.1
ICD-10 Finland
Heart transplant status
13.4
34.9
33
25
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
11.1
34.7
37
34
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
77.5
33.9
38
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
33.8
925
6517
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
33.5
648
4114
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
33.4
32
*
AJ2
HP
Reconstruction of the ascending aorta
75.5
32.9
37
5
WX882
NOMESCO Finland
High dependency care
3.4
32.4
122
377
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
40.8
32.2
40
10
I34.1
ICD-10 Finland
Mitral (valve) prolapse
4.2
32.0
88
219
5273
FHL
Repair with flap prosthesis or graft
167.6
31.8
33
*
21
HP
Aortic Valve Replacement (AVR)
53.8
31.4
37
7
ZXD05
NOMESCO Finland
Urgent procedure
1.8
31.2
616
3920
RS224, ,
NOMESCO Finland
8.1
29.9
40
50
I50.1
ICD-10 Finland
Left ventricular failure
3.3
29.7
113
351
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.8
29.7
159
602
I50.0
ICD-10 Finland
Congestive heart failure
3.0
29.3
132
454
5513
FHL
Coarctation resection, plastic or bypass
+∞
29.2
28
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
28.9
148
547
ZXE00
NOMESCO Finland
One hour or less
1.7
28.3
771
5347
207
Kela drug reimbursment
Chronic arrhythmias
2.2
28.2
278
1388
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
29.0
27.6
37
13
C07AA07
ATC
sotalol; systemic
4.0
27.6
80
207
Q20.48
ICD-10 Finland
Single ventricle
98.1
26.7
29
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
26.1
25
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
26.1
524
3322
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
6.3
25.7
43
69
I47.1
ICD-10 Finland
Supraventricular tachycardia
3.0
25.5
115
396
R50.9
ICD-10 Finland
Fever, unspecified
1.9
25.3
368
2109
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
25.3
425
2551
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
25.2
675
4629
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
25.1
453
2777
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
5.6
24.9
47
85
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.5
24.9
171
731
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
24.9
466
2889
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.7
24.8
144
568
250, ,
Kela drug reimbursment
4.6
24.4
58
129
I35
ICD-10 Finland
Nonrheumatic aortic valve disorders
34.9
24.3
31
9
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.8
24.1
54
114
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
56.7
24.1
28
5
7464A
ICD-9 Finland
Other congenital anomalies of heart, Congenital insufficiency of aortic valve
+∞
24.0
23
*
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
24.0
23
*
Q23.8
ICD-10 Finland
Other congenital malformations of aortic and mitral valves
+∞
24.0
23
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.3
23.9
92
288
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.6
23.9
57
127
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
21.6
23.5
34
16
C09CA01
ATC
losartan; oral
1.8
23.2
456
2859
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
23.0
22
*
Q23.9
ICD-10 Finland
Congenital malformation of aortic and mitral valves, unspecified
+∞
23.0
22
*
7463D
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[BIKUSPINEN AORTALÄPPÄ]
+∞
23.0
22
*
81
HP
Angiography of the heart and coronary arteries
2.9
22.8
107
377
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
121.4
22.6
24
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
121.4
22.6
24
*
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
6.2
22.4
38
62
C10AA05
ATC
atorvastatin; oral
1.6
22.3
739
5309
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.0
22.2
64
165
C09AA02
ATC
enalapril; systemic
1.9
22.1
321
1832
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
22.1
368
2193
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
21.9
21
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.4
21.6
54
125
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
21.3
528
3517
WX704
NOMESCO Finland
Intubation
2.2
21.3
181
848
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
34.2
21.1
27
8
R55
ICD-10 Finland
Syncope and collapse
2.1
21.1
211
1055
K22
ICPC
Risk factor cardiovascular disease
2.7
20.9
120
470
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
111.2
20.6
22
*
PC1AD
NOMESCO Finland
CT of thoracic aorta
20.3
20.4
30
15
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
58.1
19.9
23
*
W0X00, ,
SPAT
29.2
19.6
26
9
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
19.5
550
3774
XF620
NOMESCO Finland
Examination of circulation with color method
8.4
19.3
25
30
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.5
18.8
118
483
FMC20
NOMESCO Finland
Suture of leaflet of aortic valve
+∞
18.8
18
*
Q23.1
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
18.8
18
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
70.5
18.7
21
*
R06.0
ICD-10 Finland
Dyspnoea
1.6
18.7
484
3247
Z3231
NOMESCO Finland
Registered nurse
1.6
18.6
554
3843
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
18.6
326
1965
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.9
18.6
89
317
Q20.1
ICD-10 Finland
Double outlet right ventricle
38.8
18.6
23
6
G04BE03
ATC
sildenafil; oral
4.1
18.4
51
128
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.9
18.2
86
304
TFP34
NOMESCO Finland
Electrophysiological investigation
3.0
18.2
83
288
K29
ICPC
Cardiovascular sympt/complt other
2.9
18.0
88
317
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
18.0
998
7930
I71.09
ICD-10 Finland
Aortic dissection [regardless of location]
16.7
17.9
28
17
Q21.0
ICD-10 Finland
Ventricular septal defect
20.2
17.7
26
13
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
67.2
17.7
20
*
G45.3
ICD-10 Finland
Amaurosis fugax
4.1
17.6
48
119
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
17.2
143
663
GD1LA
NOMESCO Finland
GD
4.3
16.9
43
101
Q23.20
ICD-10 Finland
Congenital mitral stenosis
+∞
16.7
16
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
171.3
16.5
17
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.3
16.4
128
578
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
4.5
16.4
40
91
C08CA01
ATC
amlodipine; oral
1.5
16.4
620
4522
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
15.5
16.2
26
17
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.2
16.1
146
701
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
4.5
16.1
39
88
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
47.9
16.0
19
*
A40.8
ICD-10 Finland
Other streptococcal sepsis
5.5
15.7
30
55
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
15.7
1447
16062
I33.9
ICD-10 Finland
Acute endocarditis, unspecified
22.2
15.5
22
10
4241A
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[INSUFFICIENTIA VALVULAE AORTAE (NON RHEUMATICA)]
161.2
15.5
16
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
5.1
15.3
32
64
205
Kela drug reimbursment
Chronic hypertension
1.6
15.2
378
2495
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
4.6
15.2
36
80
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
5.0
15.0
32
65
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
14.8
228
1318
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
57.1
14.8
17
*
GD1AD
NOMESCO Finland
Thorax CT examination
2.2
14.8
131
624
I38
ICD-10 Finland
Endocarditis, valve unspecified
16.6
14.8
23
14
L04AD02
ATC
tacrolimus; systemic
3.7
14.7
46
126
7AX01, ,
NOMESCO Finland
18.5
14.7
22
12
74679
ICD-8 Finland
Congenital anomalies of heart, Aliae malformationes valvulae aortae sive ventriculi sinistri
151.0
14.5
15
*
602
Kela drug reimbursment
Children's severe malnutrition
4.0
14.4
41
105
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
12.6
14.4
25
20
AP1
HP
Catheterization of the left side of the heart
4.3
14.4
37
88
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
17.1
14.3
22
13
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
27.4
14.3
19
7
211
HP
AVR mechanical
42.8
14.1
17
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
13.9
191
1064
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.2
13.9
113
520
FM1AD
NOMESCO Finland
CT of heart
12.8
13.9
24
19
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
30.2
13.9
18
6
FXD00
NOMESCO Finland
Use of ECHLA without concurrent surgical procedure
30.2
13.9
18
6
C09AA04
ATC
perindopril; oral
2.5
13.8
89
370
Z50.0
ICD-10 Finland
Cardiac rehabilitation
5.0
13.6
29
59
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
13.6
13
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
13.6
13
*
127
Kela drug reimbursment
Transplant complication
3.1
13.5
56
184
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
140.9
13.5
14
*
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
4.7
13.3
30
64
I71.1
ICD-10 Finland
Thoracic aortic aneurysm, ruptured
13.9
13.2
22
16
I44.0
ICD-10 Finland
Atrioventricular block, first degree
4.2
13.2
35
85
I47.2
ICD-10 Finland
Ventricular tachycardia
3.2
13.2
53
171
WX870
NOMESCO Finland
Other postsurgical intensive care
9.7
13.2
26
27
FCB40
NOMESCO Finland
Resection and reconstruction of aortic arch using tube graft
40.3
13.2
16
*
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
40.3
13.2
16
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
40.3
13.2
16
*
I49.1
ICD-10 Finland
Atrial premature depolarization
2.6
13.1
74
288
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.1
13.1
120
580
FN1AD
NOMESCO Finland
CT of coronary arteries
3.2
13.0
50
157
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.1
13.0
127
628
N02BE01
ATC
paracetamol; systemic, rectal
1.6
13.0
1647
14932
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
16.8
13.0
20
12
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
10.1
13.0
25
25
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
28.5
13.0
17
6
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
4.9
12.9
28
58
AP3
HP
Catheterization of the right and left side of the heart
14.1
12.7
21
15
ZX199
NOMESCO Finland
Other rote
9.7
12.7
25
26
Q21.21
ICD-10 Finland
Atrioventricular duct
70.3
12.6
14
*
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.2
12.5
50
161
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
12.5
12
*
7468X
ICD-9 Finland
Other congenital anomalies of heart, Other specified anomalies of heart[MUU SYDÄMEN EPÄMUODOSTUMA]
+∞
12.5
12
*
I48.4
ICD-10 Finland
Atypical atrial flutter
6.2
12.5
21
34
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
24.5
12.5
17
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
12.3
276
1771
Q26.1
ICD-10 Finland
Persistent left superior vena cava
37.8
12.2
15
*
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
4.0
12.2
34
86
R04.0
ICD-10 Finland
Epistaxis
2.0
12.2
139
728
I44.1
ICD-10 Finland
Atrioventricular block, second degree
3.6
12.1
40
114
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
18.1
12.0
18
10
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
26.9
12.0
16
6
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.0
352
2404
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.7
11.9
37
101
XA800
NOMESCO Finland
Neuropsychological investigation
2.1
11.9
119
594
ZX120
NOMESCO Finland
Intravenous
1.8
11.9
169
952
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
46.9
11.9
14
*
GAB00
NOMESCO Finland
Emergency thoracotomy
46.9
11.9
14
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.5
11.7
74
305
UGC02
NOMESCO Finland
Rigid bronchoscopy
5.5
11.6
22
40
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.8
11.6
56
201
I42.0
ICD-10 Finland
Dilated cardiomyopathy
2.9
11.6
54
190
90492, ,
NOMESCO Finland
65.3
11.6
13
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
2.8
11.6
57
207
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
19.0
11.6
17
9
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.5
11.5
72
295
TFJ02
NOMESCO Finland
Muscle biopsy of heart
10.1
11.5
22
22
7466A
ICD-9 Finland
Other congenital anomalies of heart, Congenital mitral insufficiency
+∞
11.5
11
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
11.5
11
*
5609
FHL
Other measure in this category
+∞
11.5
11
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
11.5
11
*
FMC10
NOMESCO Finland
Reduction of leaflet of aortic valve
120.7
11.4
12
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
11.3
711
5633
WX002
NOMESCO Finland
Sedation and analgesia
1.6
11.3
307
2061
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
10.6
11.3
21
20
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.2
727
5787
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
17.1
11.2
17
10
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
11.2
660
5170
I48.3
ICD-10 Finland
Typical atrial flutter
4.1
11.1
30
74
PA1BD
NOMESCO Finland
Extensive CT of aortic arch and branches
20.1
11.1
16
8
XQ903
NOMESCO Finland
Production of other scan or drawing
20.1
11.1
16
8
Z01.2
ICD-10 Finland
Dental examination
1.4
10.9
936
7793
FM1CD
NOMESCO Finland
Very extensive CT of heart
10.6
10.8
20
19
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
10.8
72
305
XF602
NOMESCO Finland
Bloodpressure monitoring
3.7
10.7
33
90
I49.5
ICD-10 Finland
Sick sinus syndrome
2.6
10.7
59
228
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
60.3
10.6
12
*
FM1BD
NOMESCO Finland
Extensive CT of heart
10.1
10.5
20
20
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
110.6
10.4
11
*
4241B
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[STENOSIS VALVULAE AORTAE (NON RHEUMATICA)]
110.6
10.4
11
*
FCA96
NOMESCO Finland
Other repair of ascending aorta
+∞
10.4
10
*
5207
FHL
VSD closure
+∞
10.4
10
*
K73
ICPC
Congenital anomaly cardiovascular
+∞
10.4
10
*
Z71.8
ICD-10 Finland
Other specified counselling
1.4
10.4
637
5009
L04AA06
ATC
mycophenolic acid; systemic
2.7
10.3
54
203
TFP35
NOMESCO Finland
Electroanatomical mapping
3.2
10.3
40
127
FM1DE, ,
SPAT
10.6
10.3
19
18
M01AH05
ATC
etoricoxib; oral
0.7
10.0
807
9600
AQ1
HP
Conventional electrophysiological examination
4.0
10.0
28
71
XF405
NOMESCO Finland
Symptom ECG
4.6
10.0
23
50
I71.01
ICD-10 Finland
Aneurysm of the descending aorta
14.6
10.0
16
11
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
40.3
10.0
12
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.8
9.9
47
168
FWW96
NOMESCO Finland
Other reoperation on heart or major thoracic vessels
16.8
9.9
15
9
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
26.1
9.8
13
5
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
20.1
9.8
14
7
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
4.9
9.8
21
43
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
9.7
136
763
A02BC02
ATC
pantoprazole; systemic
1.3
9.7
1150
9991
SPAT1079
SPAT
Echocardiography
4.1
9.7
26
64
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.4
9.7
62
258
K80
ICPC
Cardiac arrhythmia NOS
1.8
9.6
140
796
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
5.0
9.6
20
40
Q21.30
ICD-10 Finland
Tetralogy of Fallot
11.4
9.6
17
15
Q21.19
ICD-10 Finland
Atrial septal defect NOS
10.1
9.5
18
18
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
9.4
159
943
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
100.5
9.4
10
*
Q25.9
ICD-10 Finland
Congenital malformation of great arteries, unspecified
100.5
9.4
10
*
3A566, ,
NOMESCO Finland
100.5
9.4
10
*
Q32.11
ICD-10 Finland
Congenital tracheo-esophageal fissure
+∞
9.4
9
*
7465A
ICD-9 Finland
Other congenital anomalies of heart, Congenital mitral stenosis
+∞
9.4
9
*
FDA96
NOMESCO Finland
Other operation for HLHS
+∞
9.4
9
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
9.4
9
*
74659
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae mitralis
+∞
9.4
9
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
9.4
9
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.3
9.3
69
306
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
7.8
9.1
20
26
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.9
9.1
42
148
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.9
9.1
42
148
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.3
9.0
33
101
1CX08, ,
NOMESCO Finland
9.1
9.0
18
20
Q96.0
ICD-10 Finland
Karyotype 45,X
36.8
9.0
11
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
36.8
9.0
11
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
36.8
9.0
11
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
3.9
9.0
26
68
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.6
9.0
29
82
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
8.9
406
3018
ZXX09
NOMESCO Finland
Extent of procedure, more than 8 units
18.7
8.9
13
7
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
18.7
8.9
13
7
C10AA03
ATC
pravastatin; oral
1.9
8.9
105
557
C09CA06
ATC
candesartan; oral
1.4
8.9
392
2896
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.9
326
2325
3A422, ,
NOMESCO Finland
24.1
8.9
12
5
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
3.4
8.9
31
92
I71.6
ICD-10 Finland
Thoracoabdominal aortic aneurysm, without mention of rupture
12.6
8.9
15
12
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.6
8.8
50
196
J01DB01
ATC
cefalexin; oral
1.4
8.8
1563
14332
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.5
8.8
54
220
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.9
8.8
109
588
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
3.8
8.8
26
69
R00.2
ICD-10 Finland
Palpitations
1.8
8.7
135
783
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
4.3
8.7
22
52
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.2
8.6
69
317
342
Kela drug reimbursment
Dronedarone
4.8
8.6
19
40
FPK00
NOMESCO Finland
Implantation of electrocardiograph with loop recorder
4.8
8.6
19
40
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
8.6
188
1197
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
9.0
8.5
17
19
Z3226
NOMESCO Finland
Physiotherapist
1.5
8.5
322
2312
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
27.6
8.5
11
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
27.6
8.5
11
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
27.6
8.5
11
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
27.6
8.5
11
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
8.5
110
603
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.8
8.5
42
154
PD5DM
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
90.4
8.4
9
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.8
8.4
117
656
B34.9
ICD-10 Finland
Viral infection, unspecified
2.1
8.4
79
387
-, ,
ICD-10 Finland
2.9
8.4
39
138
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
12.8
8.4
14
11
FDH96
NOMESCO Finland
Other operation for interrupted or hypoplastic aortic arch
+∞
8.3
8
*
Q25.4
ICD-10 Finland
Other congenital malformations of aorta
+∞
8.3
8
*
FLE00
NOMESCO Finland
Excision of subvalvular membrane of left ventricle
+∞
8.3
8
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
2.7
8.3
43
161
C10AX09
ATC
ezetimibe; oral
1.5
8.3
288
2032
FM1EE, ,
SPAT
3.3
8.2
30
92
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
4.6
8.1
19
42
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
33.5
8.1
10
*
FM1AT
NOMESCO Finland
Percutaneous implantation of aortic valve endoprosthesis
33.5
8.1
10
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.0
795
6663
SPAT1263
SPAT
Sampling
1.3
8.0
694
5706
1EA01, ,
NOMESCO Finland
22.1
8.0
11
5
C07AB03
ATC
atenolol; systemic
2.1
7.9
75
369
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.2
7.9
62
283
ZYC01
NOMESCO Finland
Remote contact by phone
1.8
7.9
125
729
Z01.7
ICD-10 Finland
Laboratory examination
1.5
7.9
290
2070
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
3.1
7.8
31
100
3A064, ,
NOMESCO Finland
10.8
7.8
14
13
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
9.4
7.8
15
16
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.8
761
6362
4241C
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[INSUFFICIENTIA/STENOSIS VALVULAE AORTAE (NON RHEUM)]
45.1
7.7
9
*
474, ,
NOMESCO Finland
45.1
7.7
9
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
45.1
7.7
9
*
R31
ICD-10 Finland
Unspecified haematuria
1.6
7.7
164
1037
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
7.7
119
690
RS221, ,
NOMESCO Finland
2.7
7.7
40
151
ZX108
NOMESCO Finland
Inhalation
3.7
7.6
23
62
Y0399
ICD-8 Finland
Investigation of circulatory system
4.0
7.6
21
53
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.6
1333
12035
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
8.9
7.5
15
17
FXZ00
NOMESCO Finland
Off-pump cardiac operation
6.2
7.5
19
31
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
10.1
7.5
14
14
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.2
7.4
60
277
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
7.4
155
974
FAE96
NOMESCO Finland
Other connection to pulmonary artery from superior vena cava
80.4
7.4
8
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
80.4
7.4
8
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
80.4
7.4
8
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
7.4
215
1460
Z31.5
ICD-10 Finland
Genetic counselling
1.8
7.4
108
615
TGW99
NOMESCO Finland
Other minor procedure in thoracic surgery
13.4
7.4
12
9
N03AX14
ATC
levetiracetam; systemic
2.3
7.4
55
246
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.9
7.3
82
429
FDJ30
NOMESCO Finland
Reconstruction of aorta for coarctation using tube graft
+∞
7.3
7
*
120, ,
NOMESCO Finland
+∞
7.3
7
*
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
2.9
7.3
32
110
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
9.4
7.3
14
15
TK800
NOMESCO Finland
Hemodialysis
2.4
7.3
46
191
324, ,
NOMESCO Finland
15.8
7.2
11
7
GAB20
NOMESCO Finland
Median sternotomy
15.8
7.2
11
7
R62.0
ICD-10 Finland
Delayed milestone
2.6
7.2
40
156
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.9
7.2
82
432
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.4
7.2
49
211
Q96.9
ICD-10 Finland
Turner syndrome, unspecified
30.1
7.1
9
*
FWC00
NOMESCO Finland
Reoperation for deep infection in surgery of heart and major thoracic vessels
30.1
7.1
9
*
74729
ICD-8 Finland
Other congenital anomalies of circulatory system, Maleformationes aortae aliae
30.1
7.1
9
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.1
238
1665
RK260, ,
NOMESCO Finland
7.9
7.1
15
19
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
12.1
7.1
12
10
1AB02, ,
NOMESCO Finland
12.1
7.1
12
10
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
7.0
50
220
SPAT1097
SPAT
Recording of ECG
1.5
7.0
199
1347
C08CA13
ATC
lercanidipine; oral
1.5
6.9
198
1340
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.5
6.9
193
1299
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
5.8
6.9
18
31
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
7.5
6.9
15
20
C09DX04
ATC
valsartan and sacubitril; oral
3.3
6.8
25
77
C07AG02
ATC
carvedilol; oral
1.9
6.8
81
433
FXL00
NOMESCO Finland
Insertion and use of extra-, para- or intracorporeal VAD
11.0
6.8
12
11
0034, ,
NOMESCO Finland
40.2
6.8
8
*
FXE00
NOMESCO Finland
Use of ECLA
40.2
6.8
8
*
3AE00, ,
NOMESCO Finland
40.2
6.8
8
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
40.2
6.8
8
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
16.7
6.7
10
6
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
16.7
6.7
10
6
I72.1
ICD-10 Finland
Aneurysm and dissection of artery of upper extremity
16.7
6.7
10
6
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
1.9
6.7
82
442
FWA00
NOMESCO Finland
Repair of wound dehiscence in surgery of heart and major thoracic vessels
22.6
6.7
9
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
22.6
6.7
9
*
C02EA02, ,
ATC
2.3
6.6
48
212
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
6.6
128
789
C08CA05
ATC
nifedipine; systemic
1.9
6.6
76
401
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.6
6.6
149
955
TJD20
NOMESCO Finland
Change of gastrostomy tube
4.0
6.6
18
45
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
7.8
6.6
14
18
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.8
6.6
96
547
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
3.6
6.6
21
59
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
3.6
6.6
21
59
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
12.3
6.6
11
9
I50
ICD-10 Finland
Heart failure
2.6
6.5
36
140
XCK00
NOMESCO Finland
Perimetry
1.9
6.5
75
396
SPAT1260
SPAT
Consultation of another employee
1.4
6.5
264
1915
3A019, ,
NOMESCO Finland
10.0
6.5
12
12
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
6.9
6.5
15
22
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
2.7
6.4
32
118
J01FA06
ATC
roxithromycin; oral
1.3
6.4
590
4861
ABX
HP
Other aortic valve operation
70.1
6.4
7
*
FMB10
NOMESCO Finland
Transannular expansion of aortic ostium
70.1
6.4
7
*
FLE10
NOMESCO Finland
Myotomy or myectomy of left ventricle for outlet obstruction
70.1
6.4
7
*
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
6.6
6.3
15
23
XX7FW, ,
NOMESCO Finland
11.0
6.3
11
10
0557, ,
NOMESCO Finland
+∞
6.3
6
*
421
HP
Reconstruction of the aortic base, e.g., composite graft
+∞
6.3
6
*
FFK20
NOMESCO Finland
Atrio-pulmonary anastomosis
+∞
6.3
6
*
FDH10
NOMESCO Finland
Reconstruction of interrupted or hypoplastic aortic arch using patch
+∞
6.3
6
*
FDJ20
NOMESCO Finland
Aortoplasty for coarctation using patch
+∞
6.3
6
*
5271
FHL
Valvulotomy
+∞
6.3
6
*
FDG10
NOMESCO Finland
Reconstruction of ascending aorta for supravalvular aortic stenosis using patch
+∞
6.3
6
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.4
6.2
41
174
XX3CW, ,
NOMESCO Finland
26.7
6.2
8
*
Q20.00
ICD-10 Finland
Common arterial trunk
26.7
6.2
8
*
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
26.7
6.2
8
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.5
6.2
166
1108
AS4
HP
Physiological pacemaker insertion DDD (R)
3.5
6.2
20
57
L04AX01
ATC
azathioprine; systemic
1.9
6.1
78
427
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.4
6.1
244
1766
RD211, ,
NOMESCO Finland
2.0
6.1
67
349
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
12.6
6.1
10
8
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
6.1
193
1337
Z2446
NOMESCO Finland
Social worker
1.6
6.1
146
952
3A077, ,
NOMESCO Finland
8.6
6.1
12
14
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
3.6
6.0
19
53
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
2.5
6.0
37
152
Q87.4
ICD-10 Finland
Marfan syndrome
10.0
6.0
11
11
B01AF02
ATC
apixaban; oral
1.5
6.0
174
1181
S18
ICPC
Laceration/cut
1.3
6.0
801
6904

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1433
4404
8.72
307.65
5.9
3.4
998.29
1153.63
ng/l
0.69
1344
3723
875
2773
4.80
255.40
4.7
2.9
30.92
29.75
s
5.56
859
2710
526
1142
5.87
239.56
4.2
3.0
167.96
169.96
ng/l
0.04
493
1026
564
1314
5.56
237.27
2.4
2.2
17.44
7.88
ug/l
11.79
544
1187
1452
7362
4.44
210.12
56.0
12.6
1.83
1.21
inr
150.83
1304
6117
290
713
4.58
109.30
5.7
4.2
3.10
3.41
g/l
3.01
284
685
718
3197
2.93
107.86
5.9
3.8
1805.32
536.48
ng/l
9.05
639
2368
90
62
15.14
101.10
8.8
6.5
6.25
6.03
kpa
1.29
85
56
85
56
15.80
97.76
7.9
6.6
5.04
5.42
kpa
0.88
85
56
464
1852
2.95
82.37
10.4
10.2
7.86
8.55
mmol/l
1.55
455
1795
1224
7805
2.44
80.70
3.6
2.9
—
—
estimate
—
0
0
800
4228
2.47
80.47
3.0
2.6
—
—
—
0
0
888
5048
2.35
74.35
2.9
2.3
348.52
279.64
u/l
1.00
859
4825
269
821
3.62
74.08
4.7
3.6
22.16
21.45
s
1.01
257
756
935
5463
2.32
73.06
3.1
2.7
—
—
—
0
0
440
1816
2.82
72.54
20.2
10.5
97.24
95.64
%
6.74
429
1765
467
2003
2.73
71.37
19.8
10.0
14.20
12.61
kpa
6.34
456
1948
467
2003
2.73
71.37
19.8
10.0
5.17
5.14
kpa
0.27
457
1945
463
1986
2.73
70.68
19.6
10.0
0.66
0.79
mmol/l
0.32
417
1672
463
2002
2.70
69.44
20.0
10.0
7.41
7.41
ph
0.05
231
1052
414
1700
2.80
68.58
20.0
10.6
114.13
124.69
g/l
20.86
408
1669
1437
10218
2.40
68.50
11.3
6.1
6.60
6.64
mmol/l
0.26
1398
9725
808
4583
2.27
66.09
5.5
4.5
—
—
—
0
0
1282
8788
2.25
65.11
7.7
7.2
15.32
13.09
umol/l
4.24
1234
8420
972
6022
2.18
63.00
4.5
3.6
63.12
64.31
ng/l
0.03
701
4058
579
2934
2.36
60.92
3.1
2.8
13.17
13.89
umol/l
1.68
555
2761
588
3014
2.34
60.13
7.8
5.1
0.83
0.82
mmol/l
1.21
570
2885
545
2749
2.34
57.49
3.0
2.8
2.43
2.35
g/l
2.80
521
2569
515
2545
2.37
56.87
3.1
2.9
21.88
23.81
%
2.78
496
2395
282
1042
2.98
56.06
27.2
13.0
15.70
16.30
%
3.19
275
1011
768
4622
2.07
50.77
6.9
5.1
74.06
88.83
%
34.02
758
4544
56
55
10.44
50.32
9.4
8.3
25.82
25.16
mmol/l
0.61
51
48
371
1759
2.36
43.89
19.0
10.7
1.22
1.35
mmol/l
2.29
364
1723
435
2217
2.23
43.29
7.1
6.4
7.37
7.37
ph
0.10
280
1330
116
285
4.26
42.92
10.8
6.1
10.79
11.13
mg/l
0.34
106
265
1953
17296
4.68
42.52
30.7
17.6
139.40
139.69
mmol/l
7.24
1939
16974
400
1991
2.26
42.05
19.5
11.5
—
—
—
0
0
1955
17346
4.72
42.01
30.6
17.8
4.01
3.98
mmol/l
6.06
1941
16985
403
2033
2.23
40.91
3.6
3.9
1.65
1.70
%
0.49
384
1864
239
997
2.58
37.00
16.7
7.4
24.59
24.50
mmol/l
0.15
231
959
257
1114
2.50
36.70
6.4
5.2
122.73
132.07
g/l
7.82
249
1087
1057
7688
1.78
34.99
15.8
8.6
1.18
1.21
mmol/l
28.58
1017
7191
1569
12913
1.96
34.09
8.9
8.4
81.16
83.29
u/l
0.89
1522
12366
1134
8457
1.77
34.08
13.6
8.9
1.18
1.21
mmol/l
27.34
1024
7445
892
6208
1.78
34.05
4.3
3.7
35.39
36.53
u/l
0.14
865
5885
32
24
13.53
33.99
8.1
3.0
103.09
98.00
g/l
0.81
32
24
675
4447
1.78
30.20
2.7
2.5
3.06
2.70
mg/l
2.97
624
3856
438
2526
1.94
30.02
2.5
2.2
—
—
—
0
0
180
733
2.60
29.09
2.0
2.0
1.21
1.47
g/l
2.59
123
638
772
5347
1.72
28.55
1.5
1.5
—
—
—
0
0
593
3817
1.78
28.40
3.5
2.2
1.50
1.20
mg/l
0.95
437
2893
382
2150
1.96
27.94
6.8
6.4
1.60
1.60
mmol/l
0.01
338
1817
984
7342
1.66
26.99
6.9
6.1
36.06
36.35
g/l
0.79
942
6962
182
788
2.44
25.78
7.4
5.0
36.92
36.92
°c
0.03
182
783
293
1548
2.04
25.47
3.6
3.6
72.55
69.73
e9/l
0.57
216
1107
1897
17303
2.53
23.73
22.9
15.1
32.28
24.23
mg/l
19.69
1698
13969
423
2639
1.76
21.74
10.7
8.3
1.13
1.10
mmol/l
1.09
416
2492
1055
8302
1.57
21.19
3.7
3.2
119.75
130.00
ug/l
0.87
1005
7858
1963
18334
3.34
21.17
29.0
18.6
79.13
77.11
umol/l
1.96
1956
18147
1044
8332
1.52
18.72
14.5
11.9
0.00
0.00
e9/l
0.33
890
6733
149
686
2.26
18.27
3.1
2.0
1.79
1.98
ug/l
0.11
138
622
151
724
2.17
16.76
14.7
5.6
1.64
1.64
%
0.03
145
686
1454
12601
1.55
16.66
4.9
4.4
10.64
10.24
mm/h
0.54
1383
11884
42
104
4.10
15.44
9.6
4.7
4496.59
77.01
mg/l
0.49
34
84
64
215
3.04
14.87
2.8
3.2
0.86
0.84
nmol/l
0.13
52
168
536
3868
1.52
14.57
3.1
2.9
4.34
4.85
e6/l
0.44
493
3524
1131
9442
1.45
14.54
8.5
7.5
0.60
0.59
e9/l
0.53
998
8086
1132
9452
1.45
14.54
8.5
7.6
0.04
0.04
e9/l
0.54
998
8092
1157
9737
1.44
14.00
9.0
7.9
0.20
0.20
e9/l
0.08
1035
8504
1223
10401
1.44
13.96
11.3
10.7
4.11
4.03
e9/l
0.55
1078
8959
1664
15080
1.58
13.58
29.6
18.8
13.58
13.46
%
3.60
1651
14915
51
158
3.28
13.57
5.2
3.9
16.32
14.37
index
0.31
41
116
81
325
2.55
13.51
21.0
8.5
10.28
11.33
mmol/l
2.96
75
291
81
326
2.55
13.42
21.0
8.5
106.56
105.36
mmol/l
2.06
75
292
332
2184
1.62
13.41
2.0
1.8
—
—
—
0
0
162
867
1.94
13.34
11.6
10.2
1.26
1.32
mg/l
0.53
157
820
62
218
2.90
13.33
2.4
2.3
—
—
—
0
0
78
310
2.58
13.27
1.3
1.2
6.62
4.97
u/ml
0.36
45
146
131
652
2.08
13.21
16.6
6.0
0.94
0.86
%
1.83
125
615
735
5743
1.44
13.09
3.8
3.6
222.94
63.80
e6/l
0.47
592
4349
1140
9640
1.42
12.97
8.6
7.6
1.70
2.01
e9/l
15.41
1023
8481
24
43
5.64
12.89
5.0
4.6
3.33
4.36
%
—
9
18
711
5546
1.43
12.68
7.5
7.1
—
—
—
0
0
1046
8737
1.41
12.63
8.6
7.9
9.13
8.88
%
2.30
993
8278
102
475
2.21
12.20
18.1
7.1
1.23
1.30
mmol/l
0.61
94
410
628
4815
1.44
12.19
4.7
4.6
7.39
7.40
ph
0.48
476
3398
1041
8721
1.40
12.17
8.5
7.8
2.99
2.93
%
0.32
987
8263
1035
8703
1.39
11.61
8.6
7.9
0.69
0.68
%
0.27
985
8249
676
5301
1.41
11.42
3.2
2.8
59.79
75.06
u/l
0.51
627
4984
1058
8969
1.38
11.07
8.5
7.8
26.29
29.32
%
16.32
1014
8587
1713
15803
1.55
11.05
4.9
4.2
1.32
1.33
mmol/l
0.34
1641
14824
316
2149
1.56
10.94
4.0
3.8
9.21
7.77
umol/l
0.74
289
1896
807
6561
1.38
10.88
4.5
4.3
99.92
68.04
e6/l
0.34
607
4585
278
1845
1.59
10.69
3.1
2.9
0.20
0.22
g/l
3.35
264
1744
1037
8815
1.36
10.40
8.5
7.6
58.01
55.66
%
8.91
1007
8499
73
324
2.30
9.84
1.9
1.8
—
—
—
0
0
73
324
2.30
9.84
1.9
1.8
—
—
—
0
0
73
324
2.30
9.84
1.9
1.8
—
—
—
0
0
73
324
2.30
9.84
1.9
1.8
—
—
—
0
0
632
4999
1.38
9.83
3.7
3.5
0.41
0.36
e6/l
0.23
494
3625
56
223
2.55
9.57
3.1
2.4
32.41
32.95
pg
0.47
56
223
1209
10603
1.35
9.48
4.8
4.2
850.87
841.37
e6/l
0.00
24
156
39
129
3.06
9.40
24.3
35.7
160.36
132.41
ug/l
0.98
25
111
301
2091
1.52
9.38
1.2
1.3
—
—
—
0
0
313
2203
1.50
9.15
1.7
1.6
—
—
—
0
0
1906
18192
1.81
9.10
14.6
11.8
28.79
28.78
u/l
0.00
1867
17781
1686
15656
1.46
8.99
5.3
4.8
1.92
1.89
mu/l
0.32
1595
14640
1443
13082
1.36
8.61
4.4
4.0
15.07
14.68
pmol/l
6.98
1352
12122
1775
16697
1.51
8.41
5.7
4.9
4.40
4.59
mmol/l
14.16
1714
15849
1978
19165
2.40
8.39
36.1
22.7
235.99
249.99
e9/l
19.60
1958
18776
1657
15393
1.42
8.30
31.4
18.8
333.23
334.16
g/l
4.01
1650
15310
1978
19174
2.38
8.22
35.9
22.6
90.27
90.19
fl
0.31
1967
19011
1978
19176
2.38
8.18
35.8
22.6
30.12
30.20
pg
1.32
1967
19011
1978
19177
2.37
8.16
36.0
22.6
4.47
4.62
e12/l
24.76
1956
18746
1978
19177
2.37
8.16
39.1
23.4
39.86
42.09
%
5.80
1967
19001
1978
19180
2.37
8.10
36.0
22.7
6.81
6.71
e9/l
1.50
1955
18741
1978
19183
2.36
8.05
36.7
22.8
133.34
138.54
g/l
37.05
1967
19015
239
1636
1.52
7.94
10.0
6.3
7.42
7.41
ph
3.12
207
1358
433
3331
1.38
7.70
3.1
3.0
552.98
556.06
mosm/kgh2o
0.10
379
2936
51
219
2.36
7.49
2.9
2.3
1.21
0.94
%
1.31
32
142
1781
16839
1.48
7.45
6.4
5.4
2.59
2.73
mmol/l
10.93
1720
15916
32
109
2.97
7.39
4.7
4.6
—
—
—
0
0
544
4369
1.33
7.27
1.7
1.7
19.92
19.78
nmol/l
0.08
483
3770
189
1254
1.56
7.24
10.4
6.6
—
—
—
0
0
22
60
3.70
7.19
1.2
1.3
33.82
29.52
s
1.41
22
60
1759
16619
1.44
7.11
5.6
4.8
1.37
1.39
mmol/l
1.48
1696
15682
1692
15901
1.39
6.84
4.9
4.7
5.87
5.91
mmol/l
0.62
1585
14814
43
182
2.39
6.55
1.4
1.5
30.22
32.73
g/l
0.58
38
163
158
1038
1.57
6.33
3.6
3.6
4.47
4.69
pmol/l
1.95
140
944
582
4809
1.29
6.17
4.4
3.7
0.39
0.01
estimate
0.51
197
1688
39
165
2.39
5.98
1.5
1.5
2518.53
1857.64
e6/l
0.45
30
110
543
4472
1.29
5.86
3.4
3.1
361.72
349.64
umol/l
1.96
511
4040
731
6253
1.26
5.79
1.9
2.0
—
—
—
0
0
35
147
2.40
5.47
1.5
1.5
—
—
—
0
0
400
3193
1.31
5.40
3.3
3.1
0.84
0.86
e6/l
0.06
240
1649
34
142
2.42
5.39
1.5
1.5
67517.62
29755.62
e6/l
0.57
21
80
1016
9071
1.24
5.39
4.2
3.6
11.26
5.28
estimate
0.33
222
1817
33
136
2.45
5.38
1.4
1.5
—
—
—
0
0
1658
15672
1.32
5.35
6.0
5.9
38.05
38.88
mmol/mol
3.98
1587
14886
107
668
1.64
5.34
5.0
4.0
23.84
24.60
mmol/l
1.16
107
657
81
471
1.75
5.26
4.6
3.2
6.18
3.08
index
0.67
63
267
1005
8980
1.24
5.23
4.2
3.6
0.00
0.00
estimate
0.50
216
1818
84
495
1.73
5.21
2.3
1.8
115.28
131.06
au/ml
0.52
30
170
188
1336
1.45
5.20
2.5
2.9
64.46
66.55
g/l
3.02
183
1251
87
523
1.69
5.03
2.3
1.8
—
—
—
0
0
222
1642
1.40
4.92
4.0
3.0
10.55
10.40
g/l
0.17
213
1533
495
4112
1.27
4.87
3.2
2.9
—
—
—
0
0
774
6762
1.23
4.86
4.1
3.4
0.01
0.02
estimate
0.40
188
1526
1014
9111
1.23
4.86
4.3
3.6
0.01
0.19
estimate
0.48
211
1682
25
95
2.65
4.82
1.0
1.0
—
—
—
0
0
25
95
2.65
4.82
1.0
1.1
—
—
—
0
0
180
1301
1.42
4.56
2.2
1.9
1.18
1.20
g/l
0.07
172
1219
9
12
7.53
4.35
1.0
1.1
—
—
—
0
0
93
605
1.56
3.99
1.3
1.2
—
—
—
0
0
9
15
6.02
3.81
1.8
1.3
—
—
—
0
0
20
77
2.61
3.80
1.5
1.2
—
—
—
0
0
172
1277
1.38
3.76
5.5
5.6
88.36
81.26
ng/l
0.46
158
1167
162
1193
1.39
3.72
4.8
4.6
1.22
1.22
mmol/l
0.05
143
1037
67
410
1.66
3.71
5.2
4.4
—
—
—
0
0
76
483
1.60
3.63
14.7
8.7
—
—
—
0
0
306
2489
1.27
3.52
1.7
1.7
—
—
—
0
0
622
5459
1.20
3.48
3.2
3.5
2.35
2.36
mmol/l
1.11
571
5040
86
573
1.52
3.36
2.1
1.6
264.95
236.98
u/ml
0.37
60
311
13
38
3.44
3.31
1.7
1.5
1.02
0.75
iu/ml
—
8
17
196
1520
1.32
3.25
5.3
5.5
0.46
0.13
%
0.41
56
402
31
156
2.00
3.25
3.4
2.6
106.68
105.56
mmol/l
0.81
31
156
357
2985
1.24
3.23
3.4
3.3
2.05
1.63
e6/l
0.43
196
1444
31
157
1.99
3.20
3.4
2.6
3.94
4.05
mmol/l
1.29
31
157
201
1569
1.31
3.19
4.9
5.3
0.87
0.89
%
0.04
67
501
80
532
1.52
3.17
1.2
1.3
—
—
—
0
0
30
152
1.99
3.10
3.4
2.6
1.19
1.19
mmol/l
0.01
30
152
74
487
1.54
3.09
3.4
3.7
78.38
59.70
mg/l
0.26
60
406
74
487
1.54
3.09
3.4
3.7
90.45
45.53
mg/l
0.42
61
408
69
447
1.56
3.08
2.7
2.5
132.24
132.84
g/l
0.08
55
357
191
1491
1.31
3.04
2.1
2.0
0.02
0.01
estimate
0.23
47
346
37
203
1.84
3.04
2.2
3.7
212.78
210.73
e6/l
0.02
27
158
43
248
1.75
3.00
2.0
3.3
845.09
1384.69
e6/l
5.03
34
200
45
263
1.73
3.00
1.5
1.2
—
—
—
0
0
34
183
1.87
2.96
1.1
1.1
—
—
—
0
0
28
141
2.00
2.95
1.5
1.6
—
—
—
0
0
96
675
1.44
2.92
3.2
3.0
1.02
1.02
ratio
0.14
84
626
56
350
1.62
2.92
4.6
5.5
1.85
2.37
mmol/l
1.02
41
224
191
1500
1.30
2.91
4.9
5.4
0.18
0.11
%
0.41
57
432
27
135
2.01
2.90
2.0
3.8
0.29
0.33
e9/l
0.29
17
76
190
1499
1.29
2.81
4.7
5.0
0.89
0.63
%
0.63
60
469
126
940
1.36
2.74
1.2
1.3
—
—
—
0
0
808
7380
1.16
2.63
3.6
3.2
6.29
6.17
ph
2.30
441
4145
30
162
1.86
2.62
1.3
1.6
12.80
12.44
umol/l
0.11
30
153
7
15
4.68
2.59
2.4
3.2
4.10
4.51
mmol/l
—
7
15
102
744
1.39
2.56
2.0
2.3
—
—
—
0
0
25
129
1.95
2.50
1.6
1.9
3.88
3.87
mg/l
0.01
25
124
11
37
2.98
2.48
1.7
1.3
170.88
88.04
ug/l
—
5
14
36
210
1.73
2.47
1.2
1.1
—
—
—
0
0
123
933
1.34
2.43
1.9
1.5
—
—
—
0
0
6
176
0.34
2.40
3.7
2.7
—
—
—
0
0
363
3133
1.19
2.37
1.6
1.7
—
—
—
0
0
34
200
1.71
2.28
2.1
3.6
313.72
608.01
e6/l
3.11
25
149
273
2304
1.21
2.27
1.6
1.7
1277.08
1154.72
nmol/l
1.47
221
1781
796
7329
1.14
2.22
1.9
2.0
1.44
1.42
mmol/l
0.21
675
6329
70
492
1.44
2.20
1.3
1.2
—
—
—
0
0
136
1722
0.77
2.20
1.8
1.7
3.31
3.47
mmol/l
0.91
99
1203
236
1970
1.22
2.19
1.5
1.5
—
—
—
0
0
64
443
1.46
2.18
3.0
3.4
2.86
3.00
ratio
0.03
31
246
49
321
1.54
2.17
1.4
1.8
71.54
67.55
mmol/l
0.20
39
271
259
2191
1.21
2.11
3.2
3.4
4.16
4.84
e9/l
1.20
236
1943
73
522
1.41
2.11
1.1
1.1
—
—
—
0
0
458
4074
1.16
2.07
4.6
3.5
1.02
1.02
kg/l
0.78
315
2666
78
568
1.39
2.04
1.4
1.4
84.55
103.49
titre
0.28
11
63
47
310
1.53
2.04
7.7
4.5
7.90
8.52
pmol/l
0.17
47
310
94
706
1.35
2.03
1.3
1.3
—
—
—
0
0
22
118
1.87
2.01
3.5
3.1
1081.09
950.88
u/ml
0.10
22
118
191
2297
0.81
1.99
2.0
2.0
3.54
3.67
ratio
0.75
152
1789
7
21
3.34
1.96
1.4
2.3
30.14
27.86
umol/l
—
7
21
7
22
3.19
1.88
1.4
2.2
37.71
34.64
umol/l
—
7
22
44
293
1.51
1.85
3.3
4.0
—
—
—
0
0
545
4945
1.14
1.85
3.4
3.0
2.89
0.07
estimate
0.77
173
1458
66
477
1.40
1.83
1.7
1.8
—
—
—
0
0
164
1346
1.24
1.82
3.5
3.8
—
—
—
0
0
43
287
1.51
1.80
1.2
1.2
—
—
—
0
0
1296
12405
1.12
1.77
4.1
3.6
49.17
48.89
u/l
0.05
1233
11848
36
233
1.55
1.73
1.3
1.5
403.04
377.55
pmol/l
0.08
30
204
49
339
1.46
1.73
1.0
1.1
—
—
—
0
0
5
13
3.85
1.71
1.0
1.0
—
—
—
0
0
37
242
1.54
1.71
2.3
3.2
32.85
38.34
%
1.21
37
242
37
243
1.53
1.68
2.3
3.2
—
—
—
0
0
65
478
1.37
1.65
1.1
1.2
—
—
—
0
0
33
212
1.57
1.65
2.4
3.1
—
—
—
0
0
71
530
1.35
1.65
1.3
1.5
269.24
286.87
ug/g
0.24
37
328
750
6982
1.12
1.64
2.1
2.0
95.38
95.73
pmol/l
0.08
445
3879
167
1396
1.21
1.58
1.2
1.4
230.02
244.99
u/ml
0.09
162
1309
93
1177
0.78
1.57
2.1
2.2
—
—
—
0
0
15
78
1.93
1.54
2.2
2.1
—
—
—
0
0
95
1196
0.78
1.54
2.0
2.2
—
—
—
0
0
64
477
1.35
1.52
1.1
1.2
—
—
—
0
0
95
1191
0.79
1.49
2.0
2.2
—
—
—
0
0
96
1202
0.79
1.49
2.3
2.2
—
—
—
0
0
88
1112
0.78
1.48
2.1
2.3
—
—
—
0
0
85
670
1.28
1.39
1.9
2.5
9003.52
5975.70
u/l
0.29
30
250
37
255
1.46
1.38
1.2
1.4
74.48
161.83
pmol/l
1.06
37
248
193
1659
1.18
1.38
1.5
1.5
—
—
—
0
0
74
946
0.77
1.38
2.3
2.3
—
—
—
0
0
24
150
1.61
1.38
1.1
1.1
—
—
—
0
0
37
525
0.70
1.36
3.3
3.0
—
—
—
0
0
41
290
1.42
1.35
1.3
1.6
—
—
—
0
0
12
61
1.97
1.32
1.9
3.1
27.06
32.86
umol/l
—
7
43
23
144
1.60
1.32
5.2
2.4
36.06
33.87
mg/l
0.07
16
100
42
300
1.41
1.31
1.5
1.4
—
8.28
—
0
8
48
353
1.37
1.28
2.3
2.5
—
13.44
—
0
9
287
2566
1.14
1.23
1.5
1.4
508.97
476.67
titre
0.11
58
516
11
56
1.97
1.22
2.5
1.6
40.06
41.20
g/l
0.30
11
56
29
196
1.49
1.22
1.2
1.4
—
—
nmol/l
—
0
0
16
264
0.60
1.22
1.4
3.1
—
—
—
0
0
5
19
2.63
1.21
1.0
1.0
—
—
—
0
0
5
19
2.63
1.21
1.0
1.1
—
—
—
0
0
8
38
2.11
1.18
2.4
3.3
—
—
—
0
0
21
322
0.65
1.18
1.2
1.6
—
—
—
0
0
47
351
1.35
1.16
1.1
1.1
—
—
—
0
0
61
776
0.78
1.13
1.2
1.6
327.09
297.59
mu/l
0.21
54
726
563
5254
1.10
1.13
3.6
3.6
46.68
52.73
mg/l
0.31
387
3581
10
51
1.97
1.11
1.4
2.1
469.20
4176.21
e6/l
—
5
29
7
31
2.26
1.10
1.7
1.8
—
—
—
0
0
7
32
2.19
1.08
1.4
2.7
—
—
—
0
0
321
2918
1.12
1.07
2.0
3.0
2.43
2.44
mmol/l
1.00
275
2617
423
3907
1.10
1.05
2.1
2.0
—
—
—
0
0
341
3118
1.11
1.02
1.6
1.7
69231193.00
28324994.77
pmol/l
0.36
286
2662
44
333
1.33
1.02
2.6
3.6
3.96
3.98
e9/l
0.03
44
333
10
53
1.89
1.01
1.5
2.0
—
—
—
0
0
22
319
0.69
0.97
1.0
1.1
2.23
3.79
eliau/ml
0.56
11
138
164
1864
0.87
0.97
4.8
4.6
31.88
30.90
%
0.51
129
1290
16
100
1.60
0.96
1.9
4.0
552.00
142.80
umol/l
—
6
59
31
224
1.39
0.96
1.2
1.4
0.54
0.59
nmol/l
0.34
31
215
22
149
1.48
0.95
1.8
2.3
—
—
—
0
0
25
175
1.43
0.93
1.4
1.7
77.00
56.12
%
2.34
17
119
43
330
1.31
0.92
1.2
1.2
—
—
—
0
0
22
315
0.69
0.92
1.2
1.5
—
—
—
0
0
21
142
1.48
0.92
1.1
1.1
—
—
—
0
0
15
94
1.60
0.90
1.0
1.2
178.00
226.56
iu/ml
0.47
15
94
32
236
1.36
0.89
3.6
3.6
17.07
9.17
umol/l
0.85
26
189
89
749
1.20
0.88
2.1
1.7
10.77
6.38
iu/ml
0.79
28
174
9
156
0.57
0.88
1.0
1.1
—
—
—
0
0
22
152
1.45
0.88
1.1
1.1
—
—
—
0
0
58
467
1.25
0.87
2.1
2.0
2.53
4.24
iu/l
2.21
22
198
564
5322
1.08
0.87
4.0
4.4
7.73
11.81
mg/mmol
0.62
377
3532
134
1170
1.16
0.86
1.2
1.3
21.49
55.39
au/ml
—
8
85
60
735
0.81
0.86
1.0
1.1
—
—
—
0
0
8
44
1.82
0.86
1.0
1.3
—
0.54
—
0
7
67
809
0.82
0.84
2.8
3.0
—
—
—
0
0
10
166
0.60
0.83
1.1
1.1
308.50
296.02
mg/l
—
10
142
22
154
1.43
0.83
1.1
1.1
—
—
—
0
0
8
46
1.74
0.82
1.1
1.2
—
—
—
0
0
454
4258
1.09
0.82
1.7
1.6
2.41
2.32
g/l
0.41
315
2620
642
6105
1.08
0.81
3.5
3.8
7.97
8.45
mmol/l
1.57
560
5311
685
7173
0.93
0.80
3.0
3.0
—
—
—
0
0
82
695
1.19
0.77
1.2
1.2
—
—
—
0
0
0
27
0.00
0.77
0.0
1.4
—
231.23
—
0
22
9
53
1.70
0.75
1.2
2.2
—
—
—
0
0
5
25
2.00
0.72
1.0
1.1
64.00
70.40
titre
—
5
25
52
425
1.23
0.72
1.8
1.6
15918.59
14099.15
e6/l
0.14
34
302
29
220
1.32
0.71
1.4
1.3
—
—
—
0
0
138
1232
1.13
0.68
3.5
2.1
6.09
6.08
ph
0.05
97
795
191
1740
1.11
0.66
2.6
2.7
33.87
68.84
u/l
0.69
160
1494
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
22
162
1.36
0.66
1.7
1.3
314244.13
57642.56
e6/l
0.45
16
115
19
259
0.73
0.65
1.3
1.3
—
—
—
0
0
75
644
1.17
0.64
2.1
1.7
—
—
—
0
0
73
626
1.17
0.63
1.6
1.7
26.03
14.78
u/ml
0.34
15
165
5
30
1.67
0.61
2.8
3.2
1.00
2.87
%
—
5
30
188
2049
0.91
0.61
1.3
1.3
—
—
—
0
0
140
1262
1.12
0.60
2.2
2.4
18.37
19.08
au/ml
0.06
15
140
227
2452
0.92
0.60
2.4
2.4
13.22
13.78
nmol/l
0.53
207
2256
134
1206
1.12
0.60
1.3
1.2
80.71
143.10
u/ml
1.93
52
440
8
52
1.54
0.59
1.5
1.0
—
—
—
0
0
8
52
1.54
0.59
1.5
1.0
—
—
—
0
0
8
52
1.54
0.59
1.5
1.0
—
—
—
0
0
529
5057
1.06
0.57
3.1
2.8
0.00
0.05
—
7
66
8
54
1.48
0.57
1.3
1.3
—
—
—
0
0
8
54
1.48
0.57
1.3
1.3
—
—
—
0
0
21
275
0.76
0.57
1.9
2.4
—
—
—
0
0
12
81
1.48
0.57
1.6
2.0
148.75
115.06
ng/l
0.43
12
81
45
374
1.21
0.57
1.5
1.7
0.88
0.81
g/l
0.17
30
294
18
133
1.36
0.55
1.1
1.0
—
—
—
0
0
6
38
1.58
0.54
1.5
1.3
—
—
—
0
0
12
82
1.47
0.54
1.1
1.4
138.50
425.82
u/l
1.46
12
74
30
372
0.80
0.54
2.7
2.5
113.98
140.74
ug/min
0.16
22
227
28
222
1.26
0.54
1.4
1.3
7.49
6.38
g/l
0.50
18
158
28
222
1.26
0.54
1.4
1.3
2.05
2.75
g/l
1.59
18
158
28
222
1.26
0.54
1.4
1.3
0.30
0.39
g/l
1.10
18
156
58
497
1.17
0.53
1.3
1.2
1.16
2.57
u/ml
—
5
35
9
62
1.45
0.53
4.2
2.9
0.63
0.60
mmol/l
—
9
62
76
864
0.87
0.53
2.0
1.8
7.79
6.76
u/l
0.34
61
643
9
133
0.68
0.52
1.0
1.0
19.44
19.65
mmol/l
—
9
127
12
83
1.45
0.51
1.2
1.3
121.71
185.59
mmol/24h
2.33
12
83
51
435
1.18
0.50
1.1
1.1
8.14
20.94
au/ml
1.57
13
104
63
723
0.87
0.50
1.4
1.6
1032.25
983.22
mu/l
0.23
57
615
77
679
1.14
0.50
1.3
1.2
0.29
0.85
u/ml
0.66
12
42
39
464
0.84
0.48
1.6
2.3
—
—
—
0
0
33
271
1.22
0.48
1.8
1.9
—
—
—
0
0
41
484
0.84
0.47
1.6
2.3
4.17
31.35
e6/l
1.26
30
340
38
318
1.20
0.47
1.3
1.3
—
—
—
0
0
10
68
1.47
0.47
1.5
2.3
24.10
29.63
%
—
10
68
37
309
1.20
0.47
1.4
1.6
—
—
—
0
0
32
386
0.83
0.46
1.0
1.1
1.27
0.93
u/ml
0.11
14
165
272
2566
1.07
0.46
2.6
3.1
120.07
124.24
ug/g
0.09
217
2118
54
469
1.16
0.44
2.7
3.2
58.99
55.92
%
0.97
54
469
25
202
1.24
0.43
1.3
1.2
—
296.00
—
0
5
111
1013
1.10
0.42
2.7
2.4
—
—
—
0
0
15
113
1.33
0.42
1.7
2.4
0.33
1.24
u/field
—
6
70
21
167
1.26
0.41
1.4
1.4
6.85
5.30
u/ml
0.15
13
103
13
96
1.36
0.41
1.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
35.54
—
0
16
0
17
0.00
0.40
0.0
1.0
—
0.19
—
0
10
17
132
1.29
0.40
1.3
2.0
16.19
23.45
umol/l
1.62
17
124
11
149
0.74
0.40
1.0
1.0
—
—
—
0
0
82
907
0.90
0.40
2.0
1.7
24.26
19.57
iu/l
0.68
71
717
79
875
0.90
0.39
1.6
1.6
—
—
—
0
0
7
104
0.67
0.39
1.3
1.3
119.86
144.04
nmol/l
—
7
104
44
505
0.87
0.38
1.0
1.1
1.92
7.48
eliau/ml
—
5
75
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
67
601
1.12
0.37
2.6
2.5
—
—
—
0
0
18
143
1.26
0.37
1.1
1.2
93.89
109.70
pmol/l
0.91
18
143
716
6978
1.04
0.36
4.8
4.9
2.10
2.25
ug/l
0.32
645
6398
58
649
0.89
0.35
1.2
1.3
127.08
221.19
miu/ml
2.51
22
288
9
125
0.72
0.35
1.0
1.0
—
—
—
0
0
283
2704
1.05
0.34
1.6
1.6
—
—
—
0
0
19
232
0.82
0.33
1.2
1.5
—
—
—
0
0
480
4648
1.04
0.33
1.4
1.5
1.63
2.06
u/ml
0.45
136
1213
38
435
0.87
0.33
1.1
1.1
2.58
5.49
u/ml
1.49
19
252
17
137
1.24
0.32
1.9
1.7
—
—
—
0
0
14
110
1.27
0.31
1.2
1.3
—
—
—
0
0
73
797
0.91
0.30
1.1
1.1
0.64
0.67
ratio
0.22
13
85
7
54
1.30
0.30
1.3
1.3
—
—
—
0
0
46
515
0.89
0.30
1.5
1.6
—
—
—
0
0
17
139
1.22
0.29
1.9
1.5
15.07
30.98
%
2.54
12
95
7
57
1.23
0.29
1.3
2.2
—
—
—
0
0
36
408
0.88
0.29
1.1
1.1
7.08
7.89
u/ml
0.09
16
216
157
1485
1.06
0.28
3.5
4.5
55.51
19.88
ug/l
0.32
125
1218
44
489
0.90
0.26
1.5
2.3
628.29
1042.89
e6/l
0.29
35
365
22
187
1.18
0.26
1.0
1.4
0.81
2.25
u/ml
1.59
11
106
12
95
1.26
0.26
3.3
3.4
18.23
356.07
ug/l
0.70
12
84
12
95
1.26
0.26
3.1
2.5
7.02
7.84
mmol/l
0.73
12
95
5
74
0.67
0.26
2.2
3.2
26.80
94.24
ug/l
—
5
74
9
73
1.23
0.25
1.2
1.8
—
—
—
0
0
32
360
0.89
0.24
1.3
1.1
66.00
142.88
iu/ml
—
5
96
51
558
0.91
0.24
1.0
1.2
0.76
1.06
u/ml
0.28
30
316
18
152
1.19
0.23
1.5
1.4
8.23
9.09
mmol/l
0.51
18
146
13
158
0.82
0.23
4.8
5.3
609.11
61.19
u/ml
—
7
50
22
190
1.16
0.23
2.0
2.7
1.27
1.74
g/24h
0.41
14
126
5
39
1.28
0.23
2.6
3.4
16.60
4.72
ug/l
—
5
39
11
88
1.25
0.22
1.0
1.2
—
—
—
0
0
53
575
0.92
0.21
1.0
1.2
6.35
7.21
u/ml
0.13
32
366
19
220
0.86
0.21
3.0
4.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
3.4
—
0.63
—
0
11
0
11
0.00
0.21
0.0
2.6
—
197.73
—
0
11
0
12
0.00
0.21
0.0
1.1
—
0.14
—
0
7
30
335
0.89
0.21
5.0
3.7
22.92
22.66
nmol/l
0.04
30
322
0
13
0.00
0.21
0.0
1.2
—
0.16
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
20
173
1.16
0.21
2.1
2.4
—
—
—
0
0
14
166
0.84
0.20
23.9
21.2
1426.14
1373.01
nmol/l
0.20
14
159
118
1122
1.05
0.20
1.2
1.2
3.10
2.01
u/ml
—
5
9
0
14
0.00
0.20
0.0
1.1
—
0.16
—
0
7
51
551
0.92
0.19
1.0
1.2
1.63
2.15
u/ml
0.17
30
340
22
193
1.14
0.19
2.1
1.8
—
—
—
0
0
37
405
0.91
0.18
1.2
1.2
—
—
—
0
0
76
716
1.06
0.18
3.2
5.2
1853.40
373.22
mg/l
0.48
50
406
13
152
0.85
0.17
1.7
2.0
—
—
—
0
0
10
120
0.83
0.16
4.7
4.3
4.66
1.63
ug/l
—
10
112
110
1149
0.95
0.16
1.3
1.2
—
—
—
0
0
20
177
1.13
0.16
1.1
1.4
9.52
3.37
u/ml
—
6
87
14
161
0.87
0.15
14.7
16.7
890.93
806.34
nmol/l
0.43
14
155
80
840
0.95
0.15
1.1
1.2
1.39
1.47
g/l
2.52
80
840
66
625
1.06
0.14
3.1
3.8
177.09
2553.29
u/ml
0.87
58
541
167
1722
0.97
0.14
1.2
1.2
—
—
—
0
0
18
202
0.89
0.14
1.2
1.2
—
—
—
0
0
107
1028
1.04
0.14
1.1
1.1
—
—
—
0
0
25
227
1.10
0.14
1.2
1.4
146.31
214.76
pmol/l
0.94
25
227
8
98
0.82
0.13
5.3
2.9
28.63
42.49
%
—
8
98
8
98
0.82
0.13
10.5
5.9
13.88
8.44
%
—
8
98
43
403
1.07
0.13
1.3
1.2
43.59
45.30
u/ml
—
7
38
10
85
1.18
0.12
1.0
1.2
0.36
8.83
u/ml
—
10
78
20
181
1.11
0.12
1.1
1.2
—
—
—
0
0
16
143
1.12
0.11
1.1
1.3
—
—
—
0
0
769
7620
1.01
0.11
2.9
2.7
76.10
73.93
nmol/l
1.29
704
7025
432
4261
1.02
0.11
3.1
3.0
0.77
0.72
ug/l
0.45
253
2557
10
115
0.87
0.10
1.1
1.2
—
—
—
0
0
19
173
1.10
0.10
1.3
1.3
—
—
—
0
0
34
320
1.06
0.09
1.2
1.2
17.13
42.40
u/l
1.72
28
275
10
87
1.15
0.09
2.0
1.7
—
—
—
0
0
6
57
1.05
0.08
1.2
1.1
—
—
—
0
0
6
73
0.82
0.07
1.2
1.5
0.50
0.50
e9/l
—
6
73
35
333
1.05
0.07
3.8
3.4
17.39
28.28
mg/l
2.20
30
225
10
112
0.89
0.07
1.4
1.2
—
—
—
0
0
85
827
1.03
0.07
2.1
2.2
0.00
0.94
estimate
0.51
35
270
15
163
0.92
0.07
1.7
1.4
2.40
1.99
mmol/l
0.98
15
153
9
88
1.02
0.07
1.7
1.5
—
—
—
0
0
9
100
0.90
0.06
4.9
2.7
16.08
16.90
%
—
9
100
61
628
0.97
0.06
1.1
1.2
3.04
2.44
u/ml
0.14
41
390
10
90
1.11
0.05
1.7
3.0
1970.40
2122.55
ml
—
10
82
136
1382
0.98
0.05
3.1
4.5
7.37
7.35
ph
0.40
101
1024
276
2785
0.99
0.04
1.3
1.3
9.38
11.36
u/ml
0.20
108
1106
13
120
1.08
0.04
1.2
1.1
—
74.20
—
0
6
138
1363
1.01
0.03
2.0
1.5
—
—
—
0
0
12
112
1.07
0.03
2.0
2.2
—
—
—
0
0
304
3054
0.99
0.02
1.3
1.3
29.96
28.05
iu/ml
0.11
85
883
203
2017
1.01
0.02
2.0
1.9
—
—
—
0
0
189
1878
1.01
0.02
2.5
2.4
359.55
364.60
nmol/l
0.11
175
1779
11
103
1.07
0.02
1.1
1.0
1624.55
1416.05
miu/ml
0.25
11
103
11
103
1.07
0.02
1.0
1.5
5.41
8.54
ug/l
0.85
11
89
35
342
1.02
0.01
1.1
1.2
—
—
—
0
0
20
207
0.97
0.01
1.1
1.1
11.19
16.61
u/ml
—
9
73
27
276
0.98
0.00
3.1
4.2
1.54
1.39
%
0.10
27
254
198
1973
1.00
0.00
1.4
1.4
—
—
—
0
0
229
2284
1.00
0.00
1.2
1.3
—
—
—
0
0
29
294
0.99
0.00
1.5
1.6
0.32
0.29
nmol/l
0.08
19
224
29
294
0.99
0.00
1.1
1.2
—
—
—
0
0
33
327
1.01
0.00
1.8
1.7
21.31
27.45
ng/l
0.72
33
327
100
1002
1.00
0.00
2.0
1.8
0.27
0.32
mg/l
0.48
52
519
15
151
0.99
0.00
1.2
1.2
—
—
—
0
0
16
155
1.03
0.00
1.0
1.2
0.40
4.09
u/ml
—
7
68
12
123
0.98
0.00
1.3
1.5
78.58
79.23
umol/l
0.03
12
123
11
111
0.99
0.00
1.0
1.3
0.23
32.28
u/ml
—
6
81
24
238
1.01
0.00
1.3
1.5
283.05
283.51
mosm/kgh2o
0.02
19
182
6
64
0.94
0.00
1.2
1.3
—
—
—
0
0
6
60
1.00
0.00
1.0
1.0
165.67
163.58
g/l
—
6
60
6
60
1.00
0.00
2.7
2.5
—
—
—
0
0
5
55
0.91
0.00
1.4
1.3
5.60
10.02
mmol/l
—
5
55
9
97
0.93
0.00
1.3
1.2
4.78
8.42
mm/h
—
9
97
0
9
0.00
-0.00
0.0
3.2
—
139.78
—
0
9
7
78
0.90
-0.00
1.0
1.1
—
0.06
—
0
5
6
62
0.97
-0.00
1.0
1.3
1.01
11.83
u/ml
—
6
54
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
317.57
—
0
7
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
372.00
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
9
91
0.99
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.36
—
0
5
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
2.0
2.3
23.95
17.53
umol/l
—
6
61
0
5
0.00
-0.00
0.0
8.4
—
221.00
—
0
5
6
68
0.88
-0.00
2.0
1.4
0.00
0.04
estimate
—
6
68
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_LVOTO_NARROW and mortality.

Females

Parameter HR [95% CI] p-value
Q17_LVOTO_NARROW 2.247 [1.81, 2.8] < 0.001
Birth year 0.991 [0.98, 1.0] 0.053

During the follow-up period (1.1.1998 — 31.12.2019), 263 out of 3839 females with Q17_LVOTO_NARROW died.

Males

Parameter HR [95% CI] p-value
Q17_LVOTO_NARROW 1.537 [1.3, 1.81] < 0.001
Birth year 0.99 [0.98, 1.0] 0.082

During the follow-up period (1.1.1998 — 31.12.2019), 418 out of 6581 males with Q17_LVOTO_NARROW died.

Mortality risk

Mortality risk for people of age

years, who have Q17_LVOTO_NARROW.

N-year risk Females Males
1 0.212% 0.276%
5 1.202% 1.713%
10 2.968% 4.62%
15 5.465% 8.948%
20 9.766% 15.278%

Relationships between endpoints

Index endpoint: Q17_LVOTO_NARROW – Left ventricular outflow tract obstruction, narrow definition

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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