Aortic stenosis

Q17_AORTIC_STENOSIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q25.3
  • Cause of death: ICD-10 Q25.3

2 out of 7 registries used, show all original rules.

53

4. Check minimum number of events

None

53

5. Include endpoints

None

53

6. Filter based on genotype QC (FinnGen only)

50

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 50 24 26
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 28.01 22.88 32.75

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
53
Matched controls
530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q253, ,
ICD-10 Finland
Stenosis of aorta
+∞
75.9
53
*
A98, ,
ICD-O-3
+∞
66.4
49
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
62.4
47
*
FM1EE, ,
ICD-O-3
+∞
47.0
38
*
J01DB01, ,
ATC
cefalexin; oral
+∞
45.5
37
*
GD1AA, ,
ICD-O-3
+∞
45.5
37
*
SAA02, ,
ICD-O-3
+∞
42.5
35
*
WX110, ,
ICD-O-3
+∞
39.6
33
*
SAA01, ,
ICD-O-3
+∞
39.6
33
*
ZXD10, ,
ICD-O-3
+∞
39.6
33
*
C03CA01, ,
ATC
furosemide; systemic
+∞
36.8
31
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
34.1
29
*
WX408, ,
ICD-O-3
+∞
34.1
29
*
K021, ,
ICD-O-3
+∞
32.7
28
*
ZXE10, ,
ICD-O-3
+∞
32.7
28
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
32.7
28
*
FM1BE, ,
ICD-O-3
+∞
31.4
27
*
GD1UA, ,
ICD-O-3
+∞
31.4
27
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
31.4
27
*
SAA03, ,
ICD-O-3
+∞
31.4
27
*
Z3231, ,
ICD-O-3
+∞
30.1
26
*
SCA01, ,
ICD-O-3
+∞
30.1
26
*
WZC00, ,
ICD-O-3
+∞
30.1
26
*
SFA10, ,
ICD-O-3
+∞
30.1
26
*
XF400, ,
ICD-O-3
+∞
30.1
26
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
30.1
26
*
TPH07, ,
ICD-O-3
+∞
28.8
25
*
FM1AE, ,
ICD-O-3
+∞
28.8
25
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
28.8
25
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
28.8
25
*
ZXE00, ,
ICD-O-3
+∞
27.5
24
*
ZXE20, ,
ICD-O-3
+∞
27.5
24
*
TPH15, ,
ICD-O-3
+∞
27.5
24
*
EB1HA, ,
ICD-O-3
+∞
26.2
23
*
J069, ,
ICD-O-3
+∞
26.2
23
*
R4110, ,
ICD-O-3
+∞
26.2
23
*
Z2221, ,
ICD-O-3
+∞
26.2
23
*
ZXD05, ,
ICD-O-3
+∞
26.2
23
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
25.0
22
*
SFA20, ,
ICD-O-3
+∞
25.0
22
*
Z012, ,
ICD-O-3
+∞
25.0
22
*
I350, ,
ICD-10 Finland
Aortic (valve) stenosis
+∞
25.0
22
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
23.7
21
*
WX404, ,
ICD-O-3
+∞
23.7
21
*
FN1AC, ,
ICD-O-3
+∞
23.7
21
*
FXA00, ,
ICD-O-3
+∞
23.7
21
*
TPH04, ,
ICD-O-3
+∞
22.5
20
*
Q251, ,
ICD-10 Finland
Coarctation of aorta
+∞
22.5
20
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
22.5
20
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
22.5
20
*
EB1AA, ,
ICD-O-3
+∞
22.5
20
*
J01DA01, ,
ATC
[U] cefalexin
+∞
22.5
20
*
B01AA03, ,
ATC
warfarin; systemic
+∞
22.5
20
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
22.5
20
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
21.3
19
*
C10AA01, ,
ATC
simvastatin; oral
+∞
21.3
19
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
21.3
19
*
WX402, ,
ICD-O-3
+∞
21.3
19
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
21.3
19
*
EB1SA, ,
ICD-O-3
+∞
20.1
18
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
20.1
18
*
C08CA01, ,
ATC
amlodipine; oral
+∞
20.1
18
*
E0000UV, ,
ATC
+∞
20.1
18
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
18.9
17
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
18.9
17
*
XF600, ,
ICD-O-3
+∞
18.9
17
*
SPAT1256, ,
ICD-O-3
+∞
18.9
17
*
Z3226, ,
ICD-O-3
+∞
18.9
17
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
18.9
17
*
SPAT1315, ,
ICD-O-3
+∞
18.9
17
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
17.7
16
*
SCA02, ,
ICD-O-3
+∞
17.7
16
*
JN3AE, ,
ICD-O-3
+∞
17.7
16
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
17.7
16
*
SDA03, ,
ICD-O-3
+∞
17.7
16
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
17.7
16
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
17.7
16
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
17.7
16
*
SPAT1325, ,
ICD-O-3
+∞
17.7
16
*
SPAT1249, ,
ICD-O-3
+∞
17.7
16
*
EBA00, ,
ICD-O-3
+∞
17.7
16
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
17.7
16
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
16.5
15
*
Z2446, ,
ICD-O-3
+∞
16.5
15
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
16.5
15
*
D82, ,
ICD-O-3
+∞
16.5
15
*
R06AE07, ,
ATC
cetirizine; oral
+∞
16.5
15
*
SPAT1263, ,
ICD-O-3
+∞
16.5
15
*
Z001, ,
ICD-O-3
+∞
16.5
15
*
WX290, ,
ICD-O-3
+∞
16.5
15
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
16.5
15
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
16.5
15
*
WYA05, ,
ICD-O-3
+∞
16.5
15
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
16.5
15
*
WX892, ,
ICD-O-3
+∞
16.5
15
*
C09AA05, ,
ATC
ramipril; oral
+∞
16.5
15
*
S18, ,
ICD-O-3
+∞
16.5
15
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
15.3
14
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
15.3
14
*
SAB03, ,
ICD-O-3
+∞
15.3
14
*
SPAT1253, ,
ICD-O-3
+∞
15.3
14
*
I351, ,
ICD-10 Finland
Aortic (valve) insufficiency
+∞
15.3
14
*
FM2CE, ,
ICD-O-3
+∞
15.3
14
*
AA1AD, ,
ICD-O-3
+∞
15.3
14
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
15.3
14
*
I251, ,
ICD-10 Finland
Atherosclerotic heart disease
+∞
15.3
14
*
-1, ,
ICD-O-3
+∞
14.2
13
*
GD1QA, ,
ICD-O-3
+∞
14.2
13
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
14.2
13
*
SDE02, ,
ICD-O-3
+∞
14.2
13
*
FM1DE, ,
ICD-O-3
+∞
14.2
13
*
KMAK, ,
ICD-O-3
+∞
14.2
13
*
WW200, ,
ICD-O-3
+∞
14.2
13
*
SDA02, ,
ICD-O-3
+∞
14.2
13
*
FN1BC, ,
ICD-O-3
+∞
14.2
13
*
K0364, ,
ICD-O-3
+∞
14.2
13
*
WZC30, ,
ICD-O-3
+∞
14.2
13
*
ZXA00, ,
ICD-O-3
+∞
14.2
13
*
I509, ,
ICD-10 Finland
Heart failure, unspecified
+∞
14.2
13
*
SPAT1316, ,
ICD-O-3
+∞
14.2
13
*
Z011, ,
ICD-10 Finland
Examination of ears and hearing
+∞
13.0
12
*
SPAT1310, ,
ICD-O-3
+∞
13.0
12
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
13.0
12
*
Z871, ,
ICD-O-3
+∞
13.0
12
*
L17, ,
ICD-O-3
+∞
13.0
12
*
SAD01, ,
ICD-O-3
+∞
13.0
12
*
R83, ,
ICD-O-3
+∞
13.0
12
*
SPAT1301, ,
ICD-O-3
+∞
13.0
12
*
C09AA02, ,
ATC
enalapril; systemic
+∞
13.0
12
*
SPAT1317, ,
ICD-O-3
+∞
13.0
12
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
13.0
12
*
R74, ,
ICD-O-3
+∞
13.0
12
*
SAB01, ,
ICD-O-3
+∞
13.0
12
*
SPAT1312, ,
ICD-O-3
+∞
13.0
12
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
13.0
12
*
UJD10, ,
ICD-O-3
+∞
11.9
11
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
11.9
11
*
ZYC01, ,
ICD-O-3
+∞
11.9
11
*
WX700, ,
ICD-O-3
+∞
11.9
11
*
I352, ,
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
+∞
11.9
11
*
D07AC13, ,
ATC
mometasone; topical
+∞
11.9
11
*
D07AC01, ,
ATC
betamethasone; topical
+∞
11.9
11
*
Z718, ,
ICD-O-3
+∞
11.9
11
*
XF402, ,
ICD-O-3
+∞
11.9
11
*
WZB00, ,
ICD-O-3
+∞
11.9
11
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
11.9
11
*
H660, ,
ICD-10 Finland
Acute suppurative otitis media
+∞
11.9
11
*
M02AA07, ,
ATC
piroxicam; topical
+∞
11.9
11
*
I10, ,
ICD-O-3
+∞
11.9
11
*
XF404, ,
ICD-O-3
+∞
11.9
11
*
N02AA05, ,
ATC
oxycodone; systemic
+∞
10.8
10
*
N03AX16, ,
ATC
[U] pregabalin
+∞
10.8
10
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
10.8
10
*
ZX120, ,
ICD-O-3
+∞
10.8
10
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
10.8
10
*
SBB10, ,
ICD-O-3
+∞
10.8
10
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
10.8
10
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
10.8
10
*
SFA30, ,
ICD-O-3
+∞
10.8
10
*
Z035, ,
ICD-10 Finland
Observation for other suspected cardiovascular diseases
+∞
10.8
10
*
C07AA05, ,
ATC
propranolol; systemic
+∞
10.8
10
*
A28, ,
ICD-O-3
+∞
10.8
10
*
Q230, ,
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
10.8
10
*
C07AB02, ,
ATC
metoprolol; systemic
+∞
10.8
10
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
10.8
10
*
ZXD30, ,
ICD-O-3
+∞
10.8
10
*
ZXA10, ,
ICD-O-3
+∞
10.8
10
*
R06AX27, ,
ATC
desloratadine; oral
+∞
10.8
10
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
10.8
10
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
10.8
10
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
10.8
10
*
R05, ,
ICD-O-3
+∞
10.8
10
*
WX882, ,
ICD-O-3
+∞
10.8
10
*
Z508, ,
ICD-10 Finland
Care involving use of other rehabilitation procedures
+∞
10.8
10
*
A97, ,
ICD-O-3
+∞
10.8
10
*
M03BX02, ,
ATC
tizanidine; oral
+∞
10.8
10
*
A03, ,
ICD-O-3
+∞
10.8
10
*
UJF32, ,
ICD-O-3
+∞
10.8
10
*
Z012, ,
ICD-10 Finland
Dental examination
+∞
9.7
9
*
T810, ,
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
+∞
9.7
9
*
I48, ,
ICD-10 Finland
Atrial fibrillation and flutter
+∞
9.7
9
*
H903, ,
ICD-10 Finland
Sensorineural hearing loss, bilateral
+∞
9.7
9
*
SPAT1153, ,
ICD-O-3
+∞
9.7
9
*
R2130, ,
ICD-O-3
+∞
9.7
9
*
WZA90, ,
ICD-O-3
+∞
9.7
9
*
I259, ,
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
+∞
9.7
9
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
9.7
9
*
J459, ,
ICD-10 Finland
Asthma, unspecified
+∞
9.7
9
*
J159, ,
ICD-10 Finland
Bacterial pneumonia, unspecified
+∞
9.7
9
*
CJE20, ,
ICD-O-3
+∞
9.7
9
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
9.7
9
*
C03DA01, ,
ATC
spironolactone; oral
+∞
9.7
9
*
K573, ,
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
+∞
9.7
9
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
9.7
9
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
9.7
9
*
C09CA01, ,
ATC
losartan; oral
+∞
9.7
9
*
L28, ,
ICD-O-3
+∞
9.7
9
*
R01AD09, ,
ATC
mometasone; nasal
+∞
9.7
9
*
Z0389, ,
ICD-10 Finland
Observation for other suspected diseases and conditions
+∞
9.7
9
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
9.7
9
*
WYA30, ,
ICD-O-3
+∞
9.7
9
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
9.7
9
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
9.7
9
*
C01AA05, ,
ATC
digoxin; systemic
+∞
9.7
9
*
ZXA05, ,
ICD-O-3
+∞
9.7
9
*
Q2311, ,
ICD-10 Finland
Bicuspid aortic valve
+∞
9.7
9
*
ZXE30, ,
ICD-O-3
+∞
9.7
9
*
Z024, ,
ICD-O-3
+∞
9.7
9
*
Z760, ,
ICD-O-3
+∞
9.7
9
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
8.6
8
*
Q2108, ,
ICD-10 Finland
Other specifed ventricular septal defect
+∞
8.6
8
*
E000001, ,
ATC
+∞
8.6
8
*
M02AA10, ,
ATC
ketoprofen; topical
+∞
8.6
8
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
8.6
8
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
8.6
8
*
I702, ,
ICD-10 Finland
Atherosclerosis of arteries of extremities
+∞
8.6
8
*
UKC02, ,
ICD-O-3
+∞
8.6
8
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
8.6
8
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
8.6
8
*
A10BA02, ,
ATC
metformin; oral
+∞
8.6
8
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
8.6
8
*
GD1PA, ,
ICD-O-3
+∞
8.6
8
*
R21, ,
ICD-O-3
+∞
8.6
8
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
8.6
8
*
201, ,
Kela drug reimbursment
Chronic cardiac insufficiency
+∞
8.6
8
*
H13, ,
ICD-O-3
+∞
8.6
8
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
8.6
8
*
Q2109, ,
ICD-10 Finland
Ventricular septal defect NOS
+∞
8.6
8
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
8.6
8
*
207, ,
Kela drug reimbursment
Chronic arrhythmias
+∞
8.6
8
*
R5110, ,
ICD-O-3
+∞
8.6
8
*
Z988, ,
ICD-10 Finland
Other specified postsurgical states
+∞
8.6
8
*
Z952, ,
ICD-10 Finland
Presence of prosthetic heart valve
+∞
8.6
8
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
8.6
8
*
M796, ,
ICD-O-3
+∞
8.6
8
*
L03, ,
ICD-O-3
+∞
8.6
8
*
SPAT1250, ,
ICD-O-3
+∞
8.6
8
*
WX872, ,
ICD-O-3
+∞
8.6
8
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
8.6
8
*
N300, ,
ICD-O-3
+∞
8.6
8
*
N05CF01, ,
ATC
zopiclone; oral
+∞
8.6
8
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
8.6
8
*
SXC05, ,
ICD-O-3
+∞
8.6
8
*
Q2110, ,
ICD-10 Finland
Persistent ostium secundum
+∞
8.6
8
*
TFC99, ,
ICD-O-3
+∞
8.6
8
*
H81, ,
ICD-O-3
+∞
8.6
8
*
AN1, ,
ICD-O-3
+∞
8.6
8
*
206, ,
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
+∞
7.5
7
*
I2081, ,
ICD-10 Finland
Other angina pectoris stenosed coronary artery
+∞
7.5
7
*
Q244, ,
ICD-10 Finland
Congenital subaortic stenosis
+∞
7.5
7
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
7.5
7
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
7.5
7
*
OAA40, ,
ICD-O-3
+∞
7.5
7
*
M545, ,
ICD-O-3
+∞
7.5
7
*
M545, ,
ICD-10 Finland
Low back pain
+∞
7.5
7
*
T90, ,
ICD-O-3
+∞
7.5
7
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
7.5
7
*
SDA01, ,
ICD-O-3
+∞
7.5
7
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
7.5
7
*
XCK10, ,
ICD-O-3
+∞
7.5
7
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
7.5
7
*
N10, ,
ICD-10 Finland
Acute tubulo-interstitial nephritis
+∞
7.5
7
*
TQX10, ,
ICD-O-3
+∞
7.5
7
*
61, ,
ICD-O-3
+∞
7.5
7
*
WX320, ,
ICD-O-3
+∞
7.5
7
*
D19, ,
ICD-O-3
+∞
7.5
7
*
B349, ,
ICD-10 Finland
Viral infection, unspecified
+∞
7.5
7
*
E7801, ,
ICD-10 Finland
Pure hypercholesterolaemia
+∞
7.5
7
*
E119, ,
ICD-10 Finland
Type 2 diabetes mellitus, without complications
+∞
7.5
7
*
Z000, ,
ICD-10 Finland
General medical examination
+∞
7.5
7
*
ZXD20, ,
ICD-O-3
+∞
7.5
7
*
KC1EE, ,
ICD-O-3
+∞
7.5
7
*
J451, ,
ICD-10 Finland
Nonallergic asthma
+∞
7.5
7
*
SPAT1260, ,
ICD-O-3
+∞
7.5
7
*
H02AB04, ,
ATC
methylprednisolone; systemic
+∞
7.5
7
*
SPAT1222, ,
ICD-O-3
+∞
7.5
7
*
VALMI, ,
ICD-O-3
+∞
7.5
7
*
SFA40, ,
ICD-O-3
+∞
7.5
7
*
FMD00, ,
ICD-O-3
+∞
7.5
7
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
7.5
7
*
N01, ,
ICD-O-3
+∞
7.5
7
*
SPAT1033, ,
ICD-O-3
+∞
7.5
7
*
K0366, ,
ICD-O-3
+∞
7.5
7
*
S060, ,
ICD-10 Finland
Concussion
+∞
7.5
7
*
A499, ,
ICD-10 Finland
Bacterial infection, unspecified
+∞
7.5
7
*
WX002, ,
ICD-O-3
+∞
7.5
7
*
B01AC04, ,
ATC
clopidogrel; oral
+∞
7.5
7
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
7.5
7
*
H01, ,
ICD-O-3
+∞
7.5
7
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
7.5
7
*
ZXE40, ,
ICD-O-3
+∞
7.5
7
*
SJC40, ,
ICD-O-3
+∞
6.4
6
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
6.4
6
*
SPAT1363, ,
ICD-O-3
+∞
6.4
6
*
FN1AT, ,
ICD-O-3
+∞
6.4
6
*
Q2100, ,
ICD-10 Finland
Multiple ventricular septal defect
+∞
6.4
6
*
B01AB10, ,
ATC
tinzaparin; parenteral
+∞
6.4
6
*
31, ,
ICD-O-3
+∞
6.4
6
*
A23, ,
ICD-O-3
+∞
6.4
6
*
Z048, ,
ICD-10 Finland
Examination and observation for other specified reasons
+∞
6.4
6
*
D01BA02, ,
ATC
terbinafine; oral
+∞
6.4
6
*
NA3AA, ,
ICD-O-3
+∞
6.4
6
*
M04AA01, ,
ATC
allopurinol; systemic
+∞
6.4
6
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
6.4
6
*
SAB02, ,
ICD-O-3
+∞
6.4
6
*
L12, ,
ICD-O-3
+∞
6.4
6
*
Z712, ,
ICD-10 Finland
Person consulting for explanation of investigation findings
+∞
6.4
6
*
Z637, ,
ICD-10 Finland
Other stressful life events affecting family and household
+∞
6.4
6
*
SFC01, ,
ICD-O-3
+∞
6.4
6
*
I500, ,
ICD-10 Finland
Congestive heart failure
+∞
6.4
6
*
I471, ,
ICD-10 Finland
Supraventricular tachycardia
+∞
6.4
6
*
SPAT1016, ,
ICD-O-3
+∞
6.4
6
*
SPAT1230, ,
ICD-O-3
+∞
6.4
6
*
H669, ,
ICD-10 Finland
Otitis media, unspecified
+∞
6.4
6
*
K020, ,
ICD-O-3
+∞
6.4
6
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
6.4
6
*
A06AD11, ,
ATC
lactulose; oral
+∞
6.4
6
*
SPAT1262, ,
ICD-O-3
+∞
6.4
6
*
Z712, ,
ICD-O-3
+∞
6.4
6
*
351, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
6.4
6
*
SPAT1223, ,
ICD-O-3
+∞
6.4
6
*
E118, ,
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
+∞
6.4
6
*
EB1MA, ,
ICD-O-3
+∞
6.4
6
*
M751, ,
ICD-10 Finland
Rotator cuff syndrome
+∞
6.4
6
*
C01DA14, ,
ATC
isosorbide mononitrate; oral
+∞
6.4
6
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
6.4
6
*
ZXE50, ,
ICD-O-3
+∞
6.4
6
*
C08CA13, ,
ATC
lercanidipine; oral
+∞
6.4
6
*
I712, ,
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
+∞
6.4
6
*
UGC12, ,
ICD-O-3
+∞
6.4
6
*
J01DA08, ,
ATC
[U] cefaclor
+∞
6.4
6
*
602, ,
Kela drug reimbursment
Children's severe malnutrition
+∞
6.4
6
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
6.4
6
*
K045, ,
ICD-O-3
+∞
6.4
6
*
T814, ,
ICD-10 Finland
Infection following a procedure, not elsewhere classified
+∞
6.4
6
*
D01, ,
ICD-O-3
+∞
6.4
6
*
SPAT1149, ,
ICD-O-3
+∞
6.4
6
*
NB1AA, ,
ICD-O-3
+∞
6.4
6
*
Q2540, ,
ICD-10 Finland
Aortic hypoplasia
+∞
6.4
6
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
6.4
6
*
PG1DE, ,
ICD-O-3
+∞
6.4
6
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
6.4
6
*
EBA05, ,
ICD-O-3
+∞
6.4
6
*
SPAT1283, ,
ICD-O-3
+∞
6.4
6
*
GAE10, ,
ICD-O-3
+∞
6.4
6
*
C08CA02, ,
ATC
felodipine; oral
+∞
6.4
6
*
Z315, ,
ICD-10 Finland
Genetic counselling
+∞
6.4
6
*
R104, ,
ICD-O-3
+∞
6.4
6
*
M255, ,
ICD-O-3
+∞
6.4
6
*
ZY010, ,
ICD-O-3
+∞
6.4
6
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
6.4
6
*
R05, ,
ICD-10 Finland
Cough
+∞
6.4
6
*
Z208, ,
ICD-O-3
+∞
6.4
6
*
J2190, ,
ICD-10 Finland
Acute obstructive bronchitis in children
+∞
6.4
6
*
Z3229, ,
ICD-O-3
+∞
6.4
6
*
290, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
6.4
6
*
A10AE05, ,
ATC
insulin detemir; parenteral
+∞
6.4
6
*
R11, ,
ICD-10 Finland
Nausea and vomiting
+∞
6.4
6
*
XKD00, ,
ICD-O-3
+∞
6.4
6
*
J010, ,
ICD-O-3
+∞
6.4
6
*
SDE03, ,
ICD-O-3
+∞
6.4
6
*
L309, ,
ICD-O-3
+∞
6.4
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
141
9.43
13.02
46.8
11.2
2.16
1.26
inr
—
7
38
26
70
6.33
10.14
5.3
5.8
32.38
30.54
s
0.81
26
70
17
32
7.30
6.92
4.2
8.9
22.59
23.81
s
0.58
17
32
27
107
4.11
6.02
6.9
4.7
—
—
—
0
0
23
84
4.07
5.70
4.3
4.5
1.73
2.19
mg/l
0.18
15
68
28
120
3.83
5.48
4.2
3.6
—
—
—
0
0
7
5
15.80
4.71
11.9
17.6
—
—
—
0
0
42
253
4.18
4.63
19.1
15.1
6.35
6.26
mmol/l
0.11
42
236
14
36
4.90
4.42
9.1
21.2
0.83
0.61
%
1.95
14
36
14
37
4.76
4.31
9.1
20.7
1.02
1.15
%
0.39
14
37
7
7
11.27
4.14
4.6
2.9
1096.29
95.39
ug/l
—
7
7
14
39
4.50
4.10
1.2
2.2
—
—
—
0
0
21
89
3.25
3.96
30.4
18.7
—
—
—
0
0
22
98
3.13
3.79
11.1
15.2
—
—
—
0
0
10
22
5.34
3.65
9.3
26.7
61.93
67.93
%
—
10
22
11
28
4.68
3.53
34.5
45.7
—
—
—
0
0
17
68
3.21
3.47
12.5
19.3
105.88
104.00
mmol/l
0.80
17
68
23
112
2.86
3.32
5.0
4.2
26.52
44.30
ng/l
0.45
16
77
9
22
4.70
3.04
10.6
31.2
—
—
—
0
0
6
9
7.34
2.95
7.3
3.0
—
—
—
0
0
15
62
2.98
2.85
2.8
2.9
—
—
—
0
0
5
7
7.73
2.60
2.8
16.0
—
—
—
0
0
34
227
2.39
2.33
9.4
10.9
—
—
—
0
0
19
98
2.46
2.33
3.3
2.8
2.60
5.24
e6/l
1.52
19
85
7
19
4.08
2.23
9.4
30.3
10.83
10.51
%
—
7
19
35
242
2.31
2.14
7.5
9.9
0.04
0.04
e9/l
0.26
28
194
35
243
2.30
2.11
7.5
9.8
0.66
0.61
e9/l
0.24
27
195
12
52
2.69
2.05
4.5
3.3
19.92
23.27
%
0.55
12
45
35
248
2.21
1.94
7.8
9.9
1.65
2.51
e9/l
5.24
29
207
19
106
2.24
1.91
4.9
3.4
—
—
—
0
0
9
36
2.80
1.84
1.4
1.2
—
—
—
0
0
35
252
2.15
1.81
8.0
10.6
0.26
0.23
e9/l
0.22
29
208
19
110
2.13
1.73
21.3
21.7
25.42
24.63
mmol/l
0.81
19
110
7
26
2.94
1.64
6.0
24.3
—
—
—
0
0
31
219
2.00
1.63
4.6
3.4
—
—
—
0
0
37
279
2.08
1.61
5.3
4.4
—
—
—
0
0
6
22
2.94
1.48
12.3
9.0
—
—
—
0
0
20
128
1.90
1.34
1.5
1.5
—
—
—
0
0
31
229
1.85
1.33
8.0
10.1
0.64
0.64
%
0.00
31
217
48
420
2.51
1.32
24.5
10.7
—
—
—
0
0
12
65
2.09
1.26
4.5
3.0
11.79
12.94
umol/l
0.36
12
59
31
232
1.81
1.25
8.1
10.0
3.77
3.15
%
0.39
31
221
31
235
1.77
1.17
8.2
10.3
9.38
8.58
%
0.54
31
225
5
21
2.52
1.11
2.2
5.0
33.00
40.90
umol/l
—
5
21
35
278
1.76
1.09
10.9
11.3
4.42
3.74
e9/l
0.93
29
226
14
85
1.88
1.07
16.9
11.9
—
—
—
0
0
5
22
2.40
1.05
2.0
2.1
—
—
—
0
0
17
113
1.74
0.98
2.9
1.8
85.29
87.54
pmol/l
—
7
59
15
96
1.78
0.98
3.7
2.9
521.67
527.16
mosm/kgh2o
0.04
15
79
31
243
1.66
0.97
8.1
9.9
25.61
35.98
%
4.58
31
235
46
407
1.98
0.93
39.3
19.8
14.11
14.59
%
0.82
46
398
12
74
1.80
0.87
2.5
1.6
—
—
—
0
0
21
154
1.60
0.83
4.6
6.4
—
—
—
0
0
5
23
2.29
0.78
2.4
1.9
—
—
—
0
0
5
93
0.49
0.75
2.2
2.6
—
—
—
0
0
8
49
1.74
0.66
2.0
1.7
—
—
—
0
0
29
240
1.46
0.62
8.4
9.8
56.67
48.47
%
2.95
29
232
6
36
1.75
0.59
1.3
1.6
—
—
—
0
0
10
70
1.53
0.45
1.9
1.7
—
—
—
0
0
34
301
1.36
0.43
5.4
4.0
1.38
1.42
mmol/l
0.26
34
278
0
16
0.00
0.42
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
19
155
1.35
0.40
6.4
4.3
—
—
—
0
0
6
89
0.63
0.36
1.7
1.8
—
—
—
0
0
6
45
1.38
0.35
1.2
1.1
—
39.83
—
0
8
34
306
1.31
0.35
6.0
4.4
2.49
2.68
mmol/l
0.61
34
282
14
111
1.36
0.34
4.7
3.7
51.07
55.50
u/l
0.31
14
106
15
123
1.31
0.29
6.8
4.0
—
—
—
0
0
8
66
1.25
0.28
2.8
2.8
476.62
341.50
nmol/l
—
8
58
9
76
1.22
0.26
5.9
3.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
1.43
—
0
11
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
5.88
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
5.6
—
42.13
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
10
89
1.15
0.07
2.0
1.9
—
—
—
0
0
10
106
0.93
0.01
2.2
2.0
—
—
—
0
0
25
247
1.02
0.00
11.4
11.7
0.00
0.05
e9/l
0.50
17
179
10
95
1.06
0.00
4.7
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
106.88
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
4.03
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.3
—
14.65
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
24.8
—
0.75
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
13.17
—
0
6
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
5.77
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
33.53
—
0
5
0
9
0.00
-0.00
0.0
1.9
—
11.64
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
1.49
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
5.53
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
11.63
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
3.91
—
0
5
0
9
0.00
-0.00
0.0
2.0
—
6.52
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.32
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_AORTIC_STENOSIS – Aortic stenosis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).