Congenital malformations of great arteries

Q17_CONGEN_MALFO_GREAT_ARTERIES

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q25
  • Cause of death: ICD-10 Q25

2 out of 7 registries used, show all original rules.

854

4. Check minimum number of events

None

854

5. Include endpoints

None

854

6. Filter based on genotype QC (FinnGen only)

764

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q2
Name in latin
Malformationes congenitae arteriarum magnarum

Similar endpoints

List of similar endpoints to Congenital malformations of great arteries based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11820 5910 5895
Only index persons 7116 3524 3592
Unadjusted period prevalence (%)
Whole population 0.17 0.17 0.16
Only index persons 0.13 0.13 0.14
Median age at first event (years)
Whole population 0.49 0.43 0.38
Only index persons 3.34 3.12 3.56

-FinnGen-

Key figures

All Female Male
Number of individuals 764 396 368
Unadjusted period prevalence (%) 0.15 0.14 0.17
Median age at first event (years) 14.30 13.27 15.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
813
Matched controls
7976
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
40.3
321.5
207
67
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
26.6
310.5
235
120
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
307.7
302
*
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
307.7
346
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
12.8
307.1
508
918
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
34.8
273.5
183
66
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
11.3
250.4
353
506
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
23.0
192.8
149
77
XF400
NOMESCO Finland
ECG with 12 standard connections
7.7
176.2
351
717
Q23.11
ICD-10 Finland
Bicuspid aortic valve
935.0
162.5
155
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
17.8
161.1
140
92
FM2CE, ,
NOMESCO Finland
12.7
159.6
173
166
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
86.9
148.6
80
10
B01AA03
ATC
warfarin; systemic
8.7
142.4
214
315
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
9.5
141.2
194
256
61
HP
Catheterization and pressure measurement of the left side of the heart
49.8
124.8
74
16
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
28.0
124.4
87
34
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
37.2
123.9
79
23
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
28.5
123.8
86
33
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.8
117.3
190
301
XF600
NOMESCO Finland
Bloodpressure measurement
7.1
115.8
210
375
XF402
NOMESCO Finland
ECG with work load test
9.1
114.7
158
207
I35.0
ICD-10 Finland
Aortic (valve) stenosis
14.8
113.1
107
81
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
112.4
106
*
TPH07
NOMESCO Finland
Cathetrisation of artery
6.6
110.3
214
408
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.9
107.1
513
2075
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
1115.4
103.9
100
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
101.1
278
723
XFE00
NOMESCO Finland
Epicardial ultrasonography
25.3
101.0
73
31
XF404
NOMESCO Finland
Ambulatory ECG
7.7
100.3
159
244
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
96.2
91
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
31.3
92.6
62
21
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
91.8
87
*
C03CA01
ATC
furosemide; systemic
4.9
83.3
231
596
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
+∞
77.9
74
*
ZXE20
NOMESCO Finland
More than three and less than five hours
4.9
77.2
207
517
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
76.8
73
*
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
20.1
74.5
59
31
31
HP
Congenital heart failure surgery
+∞
70.4
67
*
C03DA01
ATC
spironolactone; oral
5.9
68.8
140
273
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
35.0
68.1
44
13
Q25.3
ICD-10 Finland
Stenosis of aorta
+∞
64.0
61
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
19.3
62.2
50
27
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.1
61.2
117
214
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
325.5
60.8
61
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
60.3
343
1421
C01AA05
ATC
digoxin; systemic
8.7
59.4
79
97
ZXD10
NOMESCO Finland
Scheduled procedure
3.2
58.6
415
1951
ZXE10
NOMESCO Finland
More than one and less than three hours
3.2
57.5
370
1640
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
55.5
53
*
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
55.5
53
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
4.2
55.2
176
494
Z2221
NOMESCO Finland
Medical doctor
3.2
54.4
333
1425
G04BE03
ATC
sildenafil; oral
22.2
54.3
41
19
WX872
NOMESCO Finland
Intensive care
8.3
53.6
74
95
FDE32
NOMESCO Finland
Percutaneous transluminal closure of patent ductus arteriosus
+∞
50.2
48
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
48.1
46
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
47.0
45
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
46.5
289
1228
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
69.3
46.3
53
8
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
46.0
44
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
8.0
45.4
64
84
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
442.2
43.3
43
*
C01BD01
ATC
amiodarone; systemic
12.7
42.9
43
35
62
HP
Catheterization and pressure measurement of the right side of the heart
119.4
42.9
46
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
42.8
41
*
XF622
NOMESCO Finland
Measurement of minute volume of heart
151.9
41.9
44
*
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
40.7
39
*
WX882
NOMESCO Finland
High dependency care
4.0
39.2
127
356
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
7.1
39.0
61
90
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
38.6
37
*
C07AB07
ATC
bisoprolol; oral
2.7
38.6
305
1448
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
37.5
36
*
WX402
NOMESCO Finland
General anaesthesia
2.6
36.2
294
1406
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
61.9
36.2
42
7
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
366.1
36.0
36
*
205
Kela drug reimbursment
Chronic hypertension
3.3
35.9
158
541
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
9.8
34.5
41
43
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
34.4
33
*
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
34.4
33
*
XF640, ,
NOMESCO Finland
10.8
34.3
38
36
TFP20
NOMESCO Finland
Cardiodefibrillation
5.6
34.1
68
128
RS224, ,
NOMESCO Finland
10.0
33.3
39
40
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
32.3
31
*
WX892
NOMESCO Finland
Monitored bed care
3.7
31.5
109
318
ZXD05
NOMESCO Finland
Urgent procedure
2.5
30.2
273
1354
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
6.7
29.8
49
76
R4110
NOMESCO Finland
Physiotherapy
2.4
28.3
296
1559
C07AB02
ATC
metoprolol; systemic
3.2
28.3
128
442
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
28.1
27
*
I50.9
ICD-10 Finland
Heart failure, unspecified
4.0
27.9
86
231
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.2
27.8
124
424
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.2
27.8
32
32
PD5DG
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
101.8
27.6
30
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.0
27.3
84
225
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
27.0
26
*
Z3231
NOMESCO Finland
Registered nurse
2.3
26.9
334
1883
74709
ICD-8 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
274.6
26.7
27
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
6.2
26.3
46
76
K83
ICPC
Heart valve disease NOS
52.6
26.1
31
6
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
26.0
25
*
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
26.0
25
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
26.0
25
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.2
25.9
113
381
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
40.8
25.8
32
8
K84
ICPC
Heart disease other
7.9
25.1
35
45
5513
FHL
Coarctation resection, plastic or bypass
+∞
24.9
24
*
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
35.1
24.2
31
9
PD5AD
NOMESCO Finland
CT of aorta
7.6
24.2
35
47
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
7.3
24.2
36
50
I44.2
ICD-10 Finland
Atrioventricular block, complete
8.7
24.1
31
36
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
23.9
23
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
8.7
23.2
30
35
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
22.9
22
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
22.9
22
*
FDJ42
NOMESCO Finland
Percutaneous transluminal angioplasty of thoracic aorta in coarctation
+∞
22.9
22
*
FDJ00
NOMESCO Finland
End to end reconstruction of aorta for coarctation
+∞
22.9
22
*
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
6.6
22.6
37
57
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.1
22.6
31
39
FCA60
NOMESCO Finland
Resection of aortic root and ascending aorta with reimplantation of coronary arteries and use of composite graft with mechanical valve prosthesis
84.3
22.6
25
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.7
21.8
52
114
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
21.8
21
*
Q20.48
ICD-10 Finland
Single ventricle
+∞
21.8
21
*
WX704
NOMESCO Finland
Intubation
3.4
21.8
86
272
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
21.5
196
956
PD5BD
NOMESCO Finland
Extensive CT of aorta
18.1
20.8
32
18
Q25.9
ICD-10 Finland
Congenital malformation of great arteries, unspecified
+∞
20.8
20
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
20.8
20
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
+∞
20.8
20
*
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
21.8
20.7
30
14
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
16.3
20.0
32
20
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.9
19.9
60
158
ZXE00
NOMESCO Finland
One hour or less
2.0
19.8
355
2233
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
19.7
19
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
+∞
19.7
19
*
602
Kela drug reimbursment
Children's severe malnutrition
4.1
19.5
55
138
XF620
NOMESCO Finland
Examination of circulation with color method
46.3
19.1
23
5
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
+∞
18.7
18
*
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
100.5
18.5
20
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
18.5
56
148
C07AA07
ATC
sotalol; systemic
6.3
17.7
30
48
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
13.8
17.7
30
22
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
17.6
17
*
Q25.70
ICD-10 Finland
Aneurysm, congenital of pulmonary artery
+∞
17.6
17
*
Q25.8
ICD-10 Finland
Other congenital malformations of great arteries
+∞
17.6
17
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
17.6
17
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
17.6
17
*
UGC02
NOMESCO Finland
Rigid bronchoscopy
13.2
17.3
30
23
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
17.2
198
1053
TJD20
NOMESCO Finland
Change of gastrostomy tube
7.1
17.0
26
37
XQ903
NOMESCO Finland
Production of other scan or drawing
31.6
16.9
22
7
FC1AC
NOMESCO Finland
Angiography of thoracal aortta
50.2
16.9
20
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
6.9
16.6
26
38
PD5BG
NOMESCO Finland
MRI examination of thoracal and abdominal aortta with high intensity magnet
170.1
16.4
17
*
207
Kela drug reimbursment
Chronic arrhythmias
3.0
16.4
78
275
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
15.9
197
1073
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
15.8
180
949
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
15.6
15
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
15.6
15
*
Q25.45
ICD-10 Finland
Congenital aortic aneurysm
+∞
15.6
15
*
1EA01, ,
NOMESCO Finland
+∞
15.6
15
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
15.6
15
*
FCA50
NOMESCO Finland
Resection and reconstruction of ascending aorta using tube graft
+∞
15.6
15
*
Q20.00
ICD-10 Finland
Common arterial trunk
+∞
15.6
15
*
Z31.5
ICD-10 Finland
Genetic counselling
2.6
15.4
96
390
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
159.9
15.4
16
*
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
159.9
15.4
16
*
81
HP
Angiography of the heart and coronary arteries
4.7
15.1
35
75
ZX120
NOMESCO Finland
Intravenous
2.6
14.9
93
378
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.8
14.9
34
72
R62.0
ICD-10 Finland
Delayed milestone
3.1
14.8
66
224
B01AB05
ATC
enoxaparin; parenteral
2.1
14.5
172
918
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
14.5
14
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
14.5
14
*
Q21.32
ICD-10 Finland
Pulmonary atresia with Fallot ventricular septal defect
+∞
14.5
14
*
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
14.5
14
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
+∞
14.5
14
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
14.5
14
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.2
14.4
58
185
C09AA02
ATC
enalapril; systemic
2.5
14.4
100
428
C09AA05
ATC
ramipril; oral
2.3
14.2
120
560
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
5.6
14.0
27
49
F83
ICD-10 Finland
Mixed specific developmental disorders
3.2
13.7
55
175
AP3
HP
Catheterization of the right and left side of the heart
75.0
13.5
15
*
R50.9
ICD-10 Finland
Fever, unspecified
1.9
13.5
202
1168
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
13.5
13
*
Q25.4
ICD-10 Finland
Other congenital malformations of aorta
+∞
13.5
13
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
13.5
13
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
13.5
13
*
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
13.5
13
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
139.6
13.4
14
*
WZC30
NOMESCO Finland
Teaching
2.2
13.4
124
601
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.1
12.9
56
187
AN1
HP
Coronary angiography
3.1
12.5
53
175
FBA96
NOMESCO Finland
Other suture or repair of pulmonary artery
+∞
12.4
12
*
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
12.4
12
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
12.4
12
*
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
12.4
12
*
FMD40
NOMESCO Finland
Replacement of aortic root using pulmonary autograft and reimplantation of coronary arteries (Ross)
+∞
12.4
12
*
FM1CD
NOMESCO Finland
Very extensive CT of heart
129.5
12.4
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
12.0
242
1529
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.0
11.8
52
175
P85
ICPC
Mental retardation
4.3
11.7
30
70
UDC00
NOMESCO Finland
Ear microscopy
2.4
11.6
82
353
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.1
11.6
48
156
FCA75
NOMESCO Finland
Valve-sparing repair of aortic root (David, Yacoub)
64.7
11.5
13
*
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
18.9
11.5
17
9
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.1
11.5
24
47
5609
FHL
Other measure in this category
+∞
11.4
11
*
FCC45
NOMESCO Finland
Percutaneous insertion of stent into descending aorta
+∞
11.4
11
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.4
148
812
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
119.4
11.4
12
*
5512
FHL
Cleavage or ligation of the ductus arteriosus
119.4
11.4
12
*
I28.8
ICD-10 Finland
Other specified diseases of pulmonary vessels
119.4
11.4
12
*
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.0
11.3
50
169
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
10.5
11.2
21
20
7AX01, ,
NOMESCO Finland
17.0
11.1
17
10
I50.0
ICD-10 Finland
Congestive heart failure
3.6
11.0
37
105
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
8.1
11.0
24
30
J01CA04
ATC
amoxicillin; systemic
2.2
10.9
732
6397
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
10.8
48
163
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
15.4
10.7
17
11
K78
ICPC
Atrial fibrillation/flutter
3.4
10.7
38
112
RS221, ,
NOMESCO Finland
3.7
10.7
34
93
RK260, ,
NOMESCO Finland
17.8
10.6
16
9
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.9
10.6
155
883
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.4
10.6
38
113
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
59.7
10.6
12
*
Z2446
NOMESCO Finland
Social worker
2.0
10.4
130
702
7463A
ICD-9 Finland
Other congenital anomalies of heart, Congenital stenosis of aortic valve[STENOSIS VALVULAE AORTAE CONGENITA]
+∞
10.4
10
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
+∞
10.4
10
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
10.4
10
*
FJD20
NOMESCO Finland
Bypass of pulmonary valve with ventriculopulmonary prosthesis or homograft
+∞
10.4
10
*
FBE96
NOMESCO Finland
Other expansion or reconstruction of pulmonary artery
+∞
10.4
10
*
74673
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae aortae
+∞
10.4
10
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
10.4
10
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
16.0
10.3
16
10
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.2
10.1
27
65
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
13.1
10.1
17
13
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.5
10.0
24
53
I97.0
ICD-10 Finland
Postcardiotomy syndrome
39.8
9.9
12
*
1CX08, ,
NOMESCO Finland
39.8
9.9
12
*
C08CA02
ATC
felodipine; oral
3.0
9.9
45
155
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
3.0
9.8
43
145
J45.1
ICD-10 Finland
Nonallergic asthma
2.2
9.7
91
441
Z3226
NOMESCO Finland
Physiotherapist
1.8
9.7
191
1188
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.2
9.7
88
421
TFC10
NOMESCO Finland
Catheterisation of left atrium or ventricle
10.6
9.7
18
17
I49.5
ICD-10 Finland
Sick sinus syndrome
5.1
9.6
20
39
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
4.7
9.5
22
47
21
HP
Aortic Valve Replacement (AVR)
99.3
9.4
10
*
ZXX09
NOMESCO Finland
Extent of procedure, more than 8 units
99.3
9.4
10
*
90492, ,
NOMESCO Finland
99.3
9.4
10
*
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
29.8
9.3
12
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
9.3
9
*
Q90
ICD-10 Finland
Down syndrome
+∞
9.3
9
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
9.3
9
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
9.3
9
*
FCC50
NOMESCO Finland
Resection and reconstruction of descending aorta using tube graft
+∞
9.3
9
*
FMA20
NOMESCO Finland
Plastic repair of aortic valve for stenosis
+∞
9.3
9
*
GAB00
NOMESCO Finland
Emergency thoracotomy
+∞
9.3
9
*
Q25.43
ICD-10 Finland
(Ruptured) aneurysm of sinus Valsalva
+∞
9.3
9
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
9.3
9
*
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
12.3
9.3
16
13
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
4.2
9.2
24
57
WX002
NOMESCO Finland
Sedation and analgesia
2.0
9.2
114
614
PD5CD
NOMESCO Finland
Very extensive CT angiography of aorta
36.4
9.0
11
*
ZX199
NOMESCO Finland
Other rote
7.0
8.9
21
30
AB1
HP
AVR mechanical
23.9
8.8
12
5
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.7
8.6
46
173
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
8.6
92
470
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.8
8.5
42
151
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
8.5
80
388
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
11.5
8.5
15
13
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
8.4
161
990
Q90.9
ICD-10 Finland
Down syndrome, unspecified
27.3
8.4
11
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.0
8.4
91
466
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
19.9
8.4
12
6
FM1BD
NOMESCO Finland
Extensive CT of heart
19.9
8.4
12
6
I27.0
ICD-10 Finland
Primary pulmonary hypertension
89.2
8.4
9
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
89.2
8.4
9
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
8.3
50
200
Q25.5
ICD-10 Finland
Atresia of pulmonary artery
+∞
8.3
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
8.3
8
*
5207
FHL
VSD closure
+∞
8.3
8
*
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
8.3
8
*
PD5CM
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
8.3
8
*
C07AB03
ATC
atenolol; systemic
3.3
8.3
31
95
3A019, ,
NOMESCO Finland
10.7
8.2
15
14
Z94.1
ICD-10 Finland
Heart transplant status
10.7
8.2
15
14
F82
ICD-10 Finland
Specific developmental disorder of motor function
3.0
8.1
36
122
R06.0
ICD-10 Finland
Dyspnoea
1.7
8.0
168
1058
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
33.1
8.0
10
*
FM1AD
NOMESCO Finland
CT of heart
17.0
8.0
12
7
GD1AD
NOMESCO Finland
Thorax CT examination
2.7
8.0
42
157
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
2.7
8.0
42
157
I47.2
ICD-10 Finland
Ventricular tachycardia
4.5
7.9
19
42
AA1AD
NOMESCO Finland
CT of head and brain
1.8
7.9
145
880
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
7.8
66
307
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
2.9
7.8
36
125
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
10.7
7.7
14
13
WX870
NOMESCO Finland
Other postsurgical intensive care
10.7
7.7
14
13
FN1AD
NOMESCO Finland
CT of coronary arteries
4.6
7.7
18
39
C08CA01
ATC
amlodipine; oral
1.7
7.7
166
1054
FC1BC
NOMESCO Finland
Extensive angiography of thoracal aortta
44.6
7.7
9
*
XG460
NOMESCO Finland
Short time oxymetry
6.3
7.6
19
30
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.0
7.5
32
106
324, ,
NOMESCO Finland
18.2
7.5
11
6
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
18.2
7.5
11
6
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
7.5
88
464
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.3
7.4
58
262
ZF61V, ,
NOMESCO Finland
79.3
7.4
8
*
AB2
HP
AVR bio, stent
79.3
7.4
8
*
FDJ30
NOMESCO Finland
Reconstruction of aorta for coarctation using tube graft
+∞
7.2
7
*
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
+∞
7.2
7
*
7451A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[TRANSPOSITIO CORDIS COMPLETA]
+∞
7.2
7
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
7.2
7
*
74619
ICD-8 Finland
Congenital anomalies of heart, Transposition of great vessels
+∞
7.2
7
*
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
+∞
7.2
7
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
7.2
7
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
7.2
7
*
FDH96
NOMESCO Finland
Other operation for interrupted or hypoplastic aortic arch
+∞
7.2
7
*
PD5DM
NOMESCO Finland
Very extensive MRI examination of thoracal and abdominal aorta with 3 Tesla magnet
+∞
7.2
7
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
7.2
7
*
74729
ICD-8 Finland
Other congenital anomalies of circulatory system, Maleformationes aortae aliae
+∞
7.2
7
*
FBE00
NOMESCO Finland
Expansion of pulmonary artery
+∞
7.2
7
*
74659
ICD-8 Finland
Congenital anomalies of heart, Maleformatio valvulae mitralis
+∞
7.2
7
*
Q23.9
ICD-10 Finland
Congenital malformation of aortic and mitral valves, unspecified
+∞
7.2
7
*
FDE96
NOMESCO Finland
Other closure of patent ductus arteriosus
+∞
7.2
7
*
Q23.20
ICD-10 Finland
Congenital mitral stenosis
+∞
7.2
7
*
3A077, ,
NOMESCO Finland
15.6
7.2
11
7
WX250
NOMESCO Finland
Intercostal blockade
15.6
7.2
11
7
5253
FHL
Cardiac lung machine
29.7
7.1
9
*
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.7
7.0
38
144
TFJ02
NOMESCO Finland
Muscle biopsy of heart
11.9
7.0
12
10
B34.9
ICD-10 Finland
Viral infection, unspecified
2.1
7.0
64
308
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.3
6.9
26
80
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
6.8
55
251
I34.1
ICD-10 Finland
Mitral (valve) prolapse
4.2
6.8
18
43
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
2.7
6.8
36
135
FXF00
NOMESCO Finland
Decannulation after ECHLA or ECLA
39.6
6.7
8
*
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
39.6
6.7
8
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.0
6.7
76
396
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
16.5
6.7
10
6
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
6.7
67
334
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
6.7
51
228
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
4.1
6.6
18
44
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.6
159
1034
Q76.30
ICD-10 Finland
Hemivertebra fusion or failure of segmentation with scoliosis
22.3
6.6
9
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
6.6
243
1745
F98.2
ICD-10 Finland
Feeding disorder of infancy and childhood
3.9
6.5
19
49
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
5.4
6.5
18
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.5
347
2684
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.5
464
5273
H50.31
ICD-10 Finland
Intermittent exotropia
3.0
6.4
27
89
R03BB01
ATC
ipratropium bromide; inhalant
3.6
6.4
21
59
I50.1
ICD-10 Finland
Left ventricular failure
3.2
6.4
25
79
ZX108
NOMESCO Finland
Inhalation
4.1
6.4
17
41
AJ2
HP
Reconstruction of the ascending aorta
69.1
6.4
7
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
3.5
6.3
21
60
R04.0
ICD-10 Finland
Epistaxis
2.3
6.3
48
215
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
6.2
24
75
UDQ02
NOMESCO Finland
Direct laryngoscopy
5.1
6.2
18
35
FDA96
NOMESCO Finland
Other operation for HLHS
+∞
6.2
6
*
FLE00
NOMESCO Finland
Excision of subvalvular membrane of left ventricle
+∞
6.2
6
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
6.2
6
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
6.2
6
*
FBJ00
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery
+∞
6.2
6
*
FLE10
NOMESCO Finland
Myotomy or myectomy of left ventricle for outlet obstruction
+∞
6.2
6
*
FDH10
NOMESCO Finland
Reconstruction of interrupted or hypoplastic aortic arch using patch
+∞
6.2
6
*
FMC20
NOMESCO Finland
Suture of leaflet of aortic valve
+∞
6.2
6
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
6.2
6
*
FDB20
NOMESCO Finland
Arterial switch operation for other congenital heart defect
+∞
6.2
6
*
AF1
HP
Surgery of congenital heart defect
+∞
6.2
6
*
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
6.2
6
*
FBE20
NOMESCO Finland
Reconstruction of pulmonary artery using tube graft
+∞
6.2
6
*
FAE96
NOMESCO Finland
Other connection to pulmonary artery from superior vena cava
+∞
6.2
6
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.1
6.1
25
81
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
6.0
142
918

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
469
1099
8.53
211.67
8.3
3.7
1123.36
1055.36
ng/l
0.15
435
911
236
277
11.37
190.93
5.2
5.1
197.65
198.36
ng/l
0.01
216
250
509
2047
4.85
107.07
34.6
8.8
1.52
1.17
inr
16.34
442
1701
45
11
42.43
73.23
5.3
12.7
5.00
4.89
kpa
0.20
45
11
372
1534
3.54
67.37
3.4
3.1
—
—
—
0
0
419
1938
3.31
61.59
3.5
3.2
—
—
—
0
0
269
946
3.67
61.53
6.8
3.3
2383.68
403.70
ng/l
3.31
230
587
147
404
4.14
46.97
5.6
6.7
22.79
22.31
s
0.37
142
388
486
2718
2.88
46.70
4.0
3.3
—
—
estimate
—
0
0
124
321
4.29
42.75
2.4
2.3
18.67
7.98
ug/l
4.10
117
280
171
560
3.53
42.09
28.2
10.6
7.42
7.41
ph
1.14
58
270
168
552
3.50
41.07
28.5
10.7
0.29
0.28
mmol/l
0.01
150
457
200
805
2.91
34.18
19.1
10.3
105.94
104.85
mmol/l
2.38
200
805
293
1481
2.47
31.29
5.6
4.4
—
—
—
0
0
223
1044
2.51
27.60
3.5
3.1
2.49
2.44
g/l
0.70
214
989
230
1126
2.40
25.56
3.6
3.1
13.72
13.75
umol/l
0.02
223
1075
206
962
2.47
25.39
3.5
3.2
21.31
22.65
%
0.85
199
931
186
840
2.52
24.55
2.3
2.1
—
—
—
0
0
104
348
3.22
24.07
8.6
11.2
0.66
0.57
%
1.86
104
348
226
1162
2.26
21.96
25.6
11.7
—
—
—
0
0
540
3853
2.12
21.96
16.1
7.2
6.36
6.31
mmol/l
0.13
522
3615
32
48
6.77
20.03
4.5
4.7
6.02
4.16
%
0.29
13
22
243
1338
2.12
19.55
4.5
3.3
1.78
1.50
mg/l
0.42
178
1014
161
749
2.38
19.54
1.7
1.6
—
—
—
0
0
764
6464
3.65
19.21
31.0
16.2
139.48
139.55
mmol/l
0.39
758
6327
439
2994
1.95
19.15
10.3
8.1
22.59
18.00
umol/l
1.67
418
2839
340
2137
1.96
18.77
1.6
1.6
—
—
—
0
0
762
6461
3.50
18.57
30.8
16.3
3.99
3.96
mmol/l
2.86
757
6296
51
126
4.17
18.43
11.2
23.6
11.73
11.49
%
0.17
51
126
273
1632
1.97
17.11
4.2
3.2
53.03
32.39
ng/l
0.95
180
968
229
1295
2.02
16.77
14.1
11.2
1.29
1.26
mmol/l
0.52
224
1231
227
1310
1.97
15.52
10.8
10.7
7.38
7.37
ph
1.23
160
858
221
1290
1.93
14.47
10.4
10.7
1.20
1.16
mmol/l
0.09
193
1061
289
1860
1.81
13.81
3.4
3.1
2.88
2.57
mg/l
1.54
267
1656
254
1574
1.85
13.72
3.4
2.6
448.17
283.00
u/l
1.34
248
1513
433
3151
1.74
13.41
24.6
12.2
1.20
1.22
mmol/l
14.68
421
2996
456
3389
1.73
12.89
18.8
11.9
1.20
1.22
mmol/l
8.04
426
3096
177
1005
1.93
12.37
13.3
10.6
—
—
—
0
0
768
6811
2.92
11.90
18.8
10.9
—
—
—
0
0
318
2213
1.67
10.92
5.1
4.7
40.70
32.61
u/l
1.06
309
2114
195
1189
1.80
10.74
14.9
10.5
7.42
7.41
ph
4.41
171
936
157
896
1.89
10.68
2.0
1.8
—
—
—
0
0
59
232
2.61
10.09
1.7
2.3
1.29
1.32
g/l
0.07
42
208
345
2511
1.60
9.56
9.7
7.6
36.28
37.10
g/l
1.63
332
2404
759
6800
2.43
9.50
22.2
13.9
28.34
23.36
mg/l
3.59
646
5198
511
4092
1.61
9.37
8.7
9.6
0.59
0.57
e9/l
0.92
447
3407
510
4095
1.60
9.13
8.8
9.6
0.04
0.04
e9/l
0.22
448
3407
521
4224
1.58
8.77
9.7
10.3
0.20
0.21
e9/l
0.67
465
3590
157
951
1.77
8.68
5.6
6.1
1.59
1.50
%
0.65
151
897
515
4179
1.57
8.51
9.0
9.6
1.91
2.25
e9/l
9.03
461
3588
545
4484
1.58
8.44
9.0
7.5
97.98
103.93
u/l
1.07
525
4261
393
3019
1.54
8.20
8.7
10.2
—
—
—
0
0
19
41
4.63
8.15
1.6
1.7
1.02
0.92
iu/ml
—
10
25
537
4421
1.56
8.13
11.4
12.4
3.87
3.66
e9/l
1.34
469
3712
480
3873
1.53
7.81
8.9
10.0
8.91
8.55
%
2.27
467
3735
478
3865
1.52
7.62
8.8
9.9
2.91
3.17
%
1.57
466
3727
476
3856
1.51
7.44
9.0
10.0
0.61
0.66
%
0.91
465
3718
447
3577
1.50
7.39
4.4
3.6
76.77
80.06
ug/l
0.25
429
3418
49
207
2.41
7.26
2.4
2.2
—
—
—
0
0
49
207
2.41
7.26
2.4
2.2
—
—
—
0
0
49
207
2.41
7.26
2.4
2.2
—
—
—
0
0
49
207
2.41
7.26
2.4
2.2
—
—
—
0
0
203
1383
1.59
7.03
3.0
3.4
550.51
559.84
mosm/kgh2o
0.21
189
1202
480
3928
1.49
6.90
8.8
9.7
55.19
51.37
%
8.71
471
3833
710
6355
1.76
6.68
30.0
18.7
13.51
13.31
%
4.02
705
6300
52
235
2.25
6.63
10.5
6.4
—
—
—
0
0
216
1511
1.55
6.62
3.0
3.4
5.29
5.67
e6/l
0.18
204
1344
486
4007
1.47
6.58
8.8
9.8
29.10
33.39
%
12.27
476
3889
143
921
1.63
6.18
5.6
6.1
9.09
6.84
umol/l
1.06
129
781
44
192
2.32
6.10
2.2
3.9
1082.03
1569.58
e6/l
2.71
36
134
307
2347
1.46
6.00
4.1
4.4
29.42
64.92
e6/l
0.59
250
1721
461
3810
1.43
5.84
13.1
12.6
0.00
0.00
e9/l
0.28
377
2956
30
116
2.60
5.39
4.7
3.1
16.94
17.22
%
0.16
30
111
37
159
2.34
5.33
5.1
6.9
89.89
91.85
%
0.67
37
152
278
2125
1.43
5.29
3.8
4.2
0.20
0.27
e6/l
0.61
215
1502
111
706
1.63
5.02
5.1
4.7
67.48
65.26
e9/l
0.24
75
448
343
2743
1.39
4.96
5.2
5.4
99.78
53.13
e6/l
0.25
255
1801
74
431
1.75
4.65
2.9
3.3
0.25
0.33
e6/l
0.14
74
412
14
31
4.49
4.48
1.6
1.5
24460.00
23510.67
e6/l
—
8
15
14
31
4.49
4.48
1.1
1.5
—
—
—
0
0
15
36
4.15
4.44
1.5
1.4
3422.00
1944.13
e6/l
—
10
23
22
81
2.71
4.38
2.1
2.2
—
—
—
0
0
14
32
4.35
4.37
1.6
1.4
—
—
—
0
0
96
610
1.62
4.36
8.1
8.0
77.09
61.05
ng/l
0.96
87
581
204
1522
1.42
4.31
6.0
5.3
—
—
—
0
0
16
50
3.18
4.21
4.3
2.8
4.06
4.03
mmol/l
0.09
16
50
13
29
4.45
4.18
2.0
1.2
—
—
—
0
0
10
18
5.50
3.92
2.9
3.1
23.70
31.83
%
—
10
18
61
354
1.75
3.91
3.5
5.0
1.22
1.23
mmol/l
0.53
54
308
17
58
2.92
3.89
1.5
2.6
31.71
33.07
pg
0.83
17
58
97
636
1.56
3.88
1.3
1.2
—
—
—
0
0
27
118
2.29
3.81
1.1
1.2
5.89
3.19
u/ml
0.54
18
62
15
49
3.04
3.69
4.5
2.8
105.33
105.90
mmol/l
0.17
15
49
32
153
2.09
3.65
11.6
9.4
—
—
—
0
0
77
485
1.62
3.65
4.5
5.9
0.78
0.51
%
0.55
23
160
218
1688
1.36
3.63
5.4
4.4
7.39
7.39
ph
0.36
159
1164
16
55
2.89
3.62
5.5
2.7
—
—
—
0
0
121
846
1.47
3.59
1.9
1.6
449.71
31536840.59
pmol/l
0.98
107
742
794
7554
2.33
3.48
34.6
21.3
6.91
6.84
e9/l
0.41
781
7282
793
7547
2.25
3.36
34.6
21.3
246.03
263.54
e9/l
11.70
781
7300
32
159
2.01
3.32
4.4
2.6
138.35
134.31
g/l
0.28
23
130
793
7553
2.22
3.25
34.5
21.2
4.52
4.60
e12/l
3.92
779
7282
62
382
1.64
3.23
1.4
1.2
—
—
—
0
0
476
4161
1.30
3.23
4.7
4.4
46.43
1044.88
e6/l
—
7
49
14
48
2.89
3.20
4.8
2.9
1.22
1.20
mmol/l
1.24
14
48
310
2566
1.30
3.19
7.0
8.6
—
—
—
0
0
77
503
1.55
3.15
5.1
6.5
0.05
0.13
%
0.47
20
143
219
1731
1.33
3.14
3.7
3.0
61.13
63.07
u/l
0.16
206
1625
36
617
0.55
3.10
2.6
1.9
—
—
—
0
0
35
185
1.89
3.07
2.1
3.9
248.62
187.07
e6/l
0.70
26
126
216
1709
1.33
3.06
4.5
3.7
0.00
0.01
estimate
0.88
80
594
169
1289
1.36
3.06
4.5
4.1
348.34
323.37
umol/l
2.45
152
1180
65
414
1.59
2.98
3.4
3.7
4.60
4.91
pmol/l
1.66
59
381
177
1370
1.34
2.91
1.7
1.6
22.45
20.55
nmol/l
0.87
159
1187
77
515
1.52
2.85
5.1
6.2
0.65
0.68
%
0.04
23
173
24
114
2.10
2.83
3.9
5.5
8.24
9.05
kpa
0.92
24
114
31
162
1.91
2.83
4.2
4.8
7.40
7.41
ph
0.18
31
162
34
184
1.85
2.80
2.0
3.9
379.04
575.71
e6/l
2.14
26
122
73
485
1.52
2.79
5.1
6.3
0.05
0.09
%
0.28
19
142
12
39
3.05
2.71
2.1
1.8
0.17
0.24
iu/ml
—
7
27
86
595
1.47
2.71
1.7
1.6
1106.85
1159.94
nmol/l
0.21
70
457
28
145
1.93
2.64
1.0
1.1
—
—
—
0
0
402
3494
1.25
2.64
4.2
3.8
0.00
0.01
estimate
0.80
85
592
24
118
2.03
2.61
10.0
4.2
1.44
1.35
mmol/l
0.26
24
113
207
1663
1.30
2.59
3.1
2.8
—
—
—
0
0
31
525
0.56
2.59
2.5
1.9
—
—
—
0
0
20
93
2.14
2.51
1.1
1.2
—
—
—
0
0
42
650
0.61
2.48
2.4
1.8
—
—
—
0
0
42
650
0.61
2.48
2.5
1.8
—
—
—
0
0
23
114
2.01
2.46
3.7
5.5
5.00
4.88
kpa
0.37
23
114
23
114
2.01
2.46
3.7
5.5
1.62
2.23
mmol/l
0.86
13
64
27
142
1.90
2.45
5.4
4.8
—
—
—
0
0
13
50
2.58
2.44
1.6
2.0
1.02
1.08
%
—
6
22
397
3467
1.24
2.43
4.3
3.8
0.00
4.59
estimate
0.79
87
621
33
186
1.77
2.42
2.4
3.9
30.49
37.95
%
1.60
33
186
394
3442
1.24
2.39
4.2
3.8
0.00
0.00
estimate
0.50
87
631
43
654
0.63
2.37
2.5
1.8
—
—
—
0
0
14
57
2.43
2.36
2.6
5.1
—
—
—
0
0
67
456
1.48
2.32
3.2
3.7
—
—
—
0
0
43
650
0.63
2.31
2.4
1.8
—
—
—
0
0
109
811
1.37
2.31
4.5
3.6
8.81
9.44
g/l
0.94
103
775
10
33
3.00
2.31
1.0
3.1
—
—
—
0
0
57
376
1.52
2.29
1.7
2.0
—
—
—
0
0
22
111
1.97
2.26
3.2
3.6
23.11
30.13
mg/l
0.51
16
76
17
78
2.16
2.22
4.4
5.4
0.88
0.67
index
0.82
17
78
7
18
3.84
2.21
3.4
3.2
4.33
4.69
mmol/l
—
7
18
87
1123
0.73
2.04
1.3
1.3
—
—
—
0
0
22
117
1.87
1.97
2.3
3.7
4.20
3.77
e9/l
0.36
22
117
25
139
1.79
1.95
1.0
1.1
—
—
—
0
0
173
1419
1.25
1.80
3.6
3.8
0.65
0.75
e6/l
0.29
92
739
29
173
1.67
1.80
2.1
4.2
0.32
0.39
e9/l
0.54
18
103
34
212
1.60
1.78
4.3
3.8
2.86
6.64
index
1.18
28
133
88
663
1.34
1.76
2.2
2.1
0.99
1.11
g/l
0.52
83
628
8
29
2.72
1.75
1.8
1.9
—
—
—
0
0
30
459
0.63
1.75
2.8
2.2
—
—
—
0
0
486
4425
1.19
1.69
4.8
4.6
—
2.44
—
0
8
17
88
1.91
1.67
1.1
1.2
—
—
—
0
0
66
483
1.37
1.60
2.1
2.4
8895.92
5813.62
u/l
0.24
24
167
39
552
0.68
1.59
1.5
1.6
3.53
3.44
mmol/l
0.16
23
367
11
49
2.22
1.57
1.3
1.9
13.44
10.08
umol/l
0.81
11
49
13
63
2.04
1.53
1.0
1.1
—
—
—
0
0
20
113
1.75
1.52
7.1
6.3
7.85
7.14
pmol/l
0.10
20
113
102
802
1.28
1.52
3.3
2.9
3.95
4.88
e9/l
1.08
95
726
21
121
1.72
1.50
1.6
2.1
—
—
—
0
0
5
15
3.28
1.49
1.0
1.7
—
—
—
0
0
13
64
2.01
1.47
1.0
1.0
—
—
—
0
0
277
2429
1.18
1.43
4.0
3.3
0.00
0.01
estimate
1.15
72
529
165
1381
1.22
1.42
3.9
3.9
2.76
1.92
e6/l
0.42
87
705
18
101
1.77
1.41
1.2
3.7
1.24
2.05
ratio
—
9
55
30
196
1.52
1.34
1.6
1.8
0.68
0.78
g/l
0.23
20
168
222
1921
1.18
1.34
3.5
3.3
2.36
2.38
mmol/l
1.40
209
1783
214
1846
1.19
1.34
4.1
3.6
—
0.00
—
0
8
452
4143
1.16
1.29
4.7
4.3
46.73
39.20
u/l
1.54
429
3985
8
155
0.50
1.26
1.1
3.9
—
—
—
0
0
240
2621
0.86
1.24
1.5
1.8
0.98
2.82
u/ml
3.64
50
518
323
2897
1.16
1.22
3.7
3.5
6.40
6.24
ph
1.76
157
1490
21
316
0.64
1.20
3.0
2.2
—
—
—
0
0
710
6767
1.23
1.19
14.1
11.4
28.67
26.91
u/l
1.05
696
6606
22
138
1.58
1.19
1.7
1.4
2.25
2.27
g/l
0.02
17
116
22
138
1.58
1.19
1.7
1.4
—
—
—
0
0
22
138
1.58
1.19
1.7
1.4
5.90
6.26
g/l
0.15
16
117
22
138
1.58
1.19
1.7
1.4
0.31
0.36
g/l
0.39
17
114
12
63
1.88
1.17
1.0
1.5
—
—
nmol/l
—
0
0
10
49
2.01
1.17
1.8
1.9
—
—
—
0
0
8
38
2.08
1.16
2.0
3.6
1020.50
966.05
mg
—
8
38
40
529
0.73
1.16
1.0
1.2
6.09
5.78
u/ml
0.04
27
401
536
4996
1.15
1.16
4.3
3.8
1.24
1.23
mmol/l
0.19
518
4716
16
93
1.70
1.15
1.1
1.1
—
—
—
0
0
0
35
0.00
1.15
0.0
2.8
—
22.06
—
0
28
0
35
0.00
1.15
0.0
3.1
—
—
—
0
0
194
2142
0.85
1.14
2.7
2.7
—
—
—
0
0
125
1045
1.21
1.11
1.2
1.3
26.42
27.16
iu/ml
0.03
22
277
49
366
1.33
1.10
1.2
1.2
—
—
—
0
0
50
375
1.33
1.09
5.0
8.4
382.90
324.87
mg/l
0.18
40
266
43
317
1.35
1.06
2.9
2.3
95.17
110.33
au/ml
0.40
21
134
34
241
1.40
1.05
1.3
1.3
—
—
—
0
0
40
520
0.74
1.05
1.0
1.2
1.46
1.10
u/ml
0.25
25
364
20
127
1.56
1.04
2.0
1.3
—
—
—
0
0
186
1620
1.16
1.03
4.2
3.3
1.02
1.02
kg/l
0.13
126
1057
23
327
0.68
1.02
1.0
1.1
2.71
0.76
u/ml
0.48
15
175
569
5347
1.15
1.02
5.0
4.4
4.36
4.55
mmol/l
5.00
552
5098
34
243
1.39
1.01
1.4
1.3
—
—
—
0
0
5
106
0.46
1.01
1.0
1.3
0.02
15.51
u/ml
—
5
98
33
236
1.39
0.98
1.2
2.6
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
13
75
1.71
0.97
1.1
1.5
—
—
—
0
0
0
30
0.00
0.97
0.0
2.1
—
1.05
—
0
22
121
1025
1.19
0.95
1.4
1.5
275.79
509.23
titre
2.06
19
182
17
252
0.65
0.94
1.0
1.2
—
—
—
0
0
10
54
1.83
0.92
1.4
1.1
—
—
—
0
0
551
5187
1.13
0.90
4.5
4.1
14.95
14.57
pmol/l
2.99
521
4818
16
101
1.57
0.88
4.9
3.5
—
—
—
0
0
14
86
1.61
0.85
1.1
1.2
—
—
—
0
0
6
30
1.97
0.85
1.0
1.3
133.83
149.47
nmol/l
—
6
30
8
44
1.79
0.84
2.3
5.0
—
—
—
0
0
122
1363
0.86
0.84
2.6
3.3
140.99
99.07
ug/g
0.30
104
1130
43
330
1.29
0.84
2.9
2.2
—
—
—
0
0
28
201
1.38
0.84
1.2
1.2
—
—
—
0
0
6
31
1.91
0.83
1.0
1.2
—
—
—
0
0
31
228
1.35
0.81
1.4
1.8
—
—
—
0
0
81
673
1.20
0.80
1.5
1.5
—
—
—
0
0
12
184
0.63
0.79
1.4
5.1
—
—
—
0
0
36
274
1.30
0.76
2.4
2.5
—
—
—
0
0
20
272
0.71
0.74
1.0
1.0
—
—
—
0
0
20
272
0.71
0.74
1.0
1.0
-1.87
-2.55
mmol/l
—
6
69
20
272
0.71
0.74
1.0
1.0
7.21
7.28
kpa
0.07
20
236
20
272
0.71
0.74
1.0
1.0
20.16
19.48
mmol/l
0.68
20
267
28
207
1.34
0.72
1.3
1.4
259.24
340.23
ug/g
1.11
17
120
42
511
0.80
0.72
1.1
1.2
1.33
3.39
u/ml
1.71
32
374
203
1827
1.12
0.70
2.4
2.2
—
—
—
0
0
9
140
0.63
0.70
4.3
4.8
—
—
—
0
0
22
291
0.73
0.70
1.1
1.1
—
—
—
0
0
9
57
1.56
0.69
1.1
1.1
—
—
—
0
0
5
26
1.89
0.69
1.4
1.3
—
—
—
0
0
20
268
0.73
0.69
1.0
1.0
3.07
3.29
kpa
0.54
20
233
7
41
1.68
0.69
3.7
4.6
175.43
181.47
ug/l
—
7
41
14
92
1.50
0.67
1.4
2.0
—
—
—
0
0
558
5299
1.11
0.66
4.8
4.3
1.39
1.42
mmol/l
0.94
542
5021
5
28
1.76
0.65
1.0
1.0
—
—
—
0
0
34
264
1.27
0.64
2.1
1.9
25.94
21.18
ng/l
0.59
34
264
563
5352
1.10
0.64
5.4
4.8
2.61
2.72
mmol/l
2.68
546
5070
18
241
0.73
0.63
1.2
1.6
0.47
3.77
u/ml
3.37
13
173
62
518
1.19
0.61
1.9
2.1
0.00
0.00
estimate
-0.00
17
132
8
50
1.58
0.60
1.1
1.3
157.57
191.09
pmol/l
—
8
50
8
50
1.58
0.60
1.9
3.2
29.41
2.77
nmol/l
—
8
50
93
805
1.15
0.60
1.5
1.5
172.94
398.93
u/ml
1.29
88
754
0
22
0.00
0.59
0.0
1.7
—
—
—
0
0
49
571
0.83
0.59
1.1
1.3
0.96
2.94
u/ml
1.45
32
413
17
226
0.73
0.58
1.2
1.7
5.83
11.56
u/ml
—
10
154
0
23
0.00
0.58
0.0
1.0
—
299.77
—
0
13
121
1070
1.13
0.57
1.9
1.7
—
—
—
0
0
17
121
1.39
0.57
1.4
1.1
—
—
—
0
0
236
2168
1.10
0.56
2.2
1.9
93.56
96.62
pmol/l
0.45
135
1136
16
212
0.74
0.54
1.4
1.6
—
—
—
0
0
194
1772
1.10
0.52
3.5
3.1
0.00
0.01
estimate
0.99
76
512
16
210
0.74
0.51
1.3
1.5
—
—
—
0
0
25
307
0.79
0.50
1.1
1.1
4.56
22.97
au/ml
—
5
44
20
252
0.77
0.49
1.3
4.1
7105.71
931.94
e6/l
0.47
14
179
65
725
0.87
0.48
3.2
2.7
1.12
0.71
ug/l
0.72
40
404
20
251
0.78
0.48
1.3
4.1
9.14
10.50
e6/l
0.07
14
172
165
1503
1.10
0.47
1.7
1.7
—
—
—
0
0
7
47
1.47
0.47
1.1
1.1
—
—
—
0
0
29
344
0.82
0.44
1.1
1.1
3.49
11.38
u/ml
4.51
20
218
544
5205
1.08
0.44
4.6
3.9
5.64
5.71
mmol/l
0.70
511
4831
51
573
0.86
0.43
1.6
1.8
—
—
—
0
0
67
584
1.14
0.42
1.5
1.3
116.50
143.84
u/ml
0.21
20
196
8
57
1.38
0.41
2.9
2.2
800.25
1079.77
u/ml
—
8
57
0
18
0.00
0.39
0.0
1.1
—
—
—
0
0
251
2345
1.07
0.39
2.0
2.0
1.33
1.32
mmol/l
0.08
224
2076
5
35
1.40
0.38
1.0
1.2
219.00
571.24
u/l
—
5
29
10
70
1.41
0.38
1.4
4.3
33.00
155.24
umol/l
—
5
35
9
65
1.36
0.38
1.1
1.1
—
—
—
0
0
5
36
1.36
0.37
1.0
1.1
—
—
—
0
0
8
112
0.70
0.37
1.4
1.4
—
290.00
—
0
5
19
230
0.81
0.36
1.3
4.4
—
—
—
0
0
24
195
1.21
0.35
2.8
2.1
2.10
3.72
iu/l
1.56
11
81
38
427
0.87
0.34
1.1
1.2
—
—
—
0
0
6
44
1.34
0.34
1.2
1.4
—
—
—
0
0
6
44
1.34
0.34
1.2
1.4
—
—
—
0
0
6
44
1.34
0.34
1.2
1.4
—
—
—
0
0
16
195
0.80
0.33
1.2
1.2
—
—
—
0
0
58
512
1.12
0.32
2.5
2.2
6.29
6.63
u/l
0.10
44
314
7
99
0.69
0.30
1.0
1.3
—
—
—
0
0
7
99
0.69
0.30
1.0
1.1
—
—
—
0
0
31
263
1.16
0.30
2.3
2.2
0.00
0.00
estimate
-0.00
12
101
25
208
1.18
0.30
1.2
1.2
—
—
—
0
0
33
367
0.88
0.27
4.8
5.0
7.42
7.35
ph
1.66
25
274
8
64
1.23
0.27
1.5
1.2
0.68
1.40
promille
—
8
53
5
71
0.69
0.26
1.2
1.1
18.74
41.89
iu/ml
—
5
71
26
222
1.15
0.24
1.2
1.2
—
—
—
0
0
9
75
1.18
0.24
2.0
2.0
—
—
—
0
0
245
2485
0.95
0.24
1.8
1.8
1.90
1.81
g/l
0.43
158
1362
19
158
1.18
0.24
2.1
2.1
—
22.00
—
0
5
66
699
0.92
0.24
3.4
2.5
31.79
30.63
u/l
0.12
58
569
6
82
0.72
0.24
1.5
2.0
3.49
5.01
mmol/24h
—
6
75
49
526
0.91
0.23
1.5
1.6
1043.72
932.01
mu/l
0.49
44
465
5
37
1.33
0.23
1.8
2.7
19.76
20.63
umol/l
—
5
37
64
677
0.92
0.23
2.2
1.8
—
—
—
0
0
5
40
1.23
0.22
1.0
1.1
1588.60
1296.72
miu/ml
—
5
40
95
987
0.94
0.22
1.3
1.3
15.06
6.88
u/ml
0.40
33
353
33
360
0.90
0.21
1.1
1.1
8.15
8.55
u/ml
0.04
26
241
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
3.30
—
0
11
619
6004
1.05
0.21
5.5
4.8
1.98
1.92
mu/l
0.70
593
5661
0
12
0.00
0.21
0.0
1.3
—
63.58
—
0
12
0
14
0.00
0.20
0.0
1.1
—
11.83
—
0
14
315
3017
1.04
0.20
4.2
3.4
73.60
71.36
nmol/l
0.77
295
2827
33
358
0.90
0.20
1.0
1.1
—
—
—
0
0
6
49
1.20
0.19
1.0
1.2
226.17
196.80
iu/ml
—
6
49
11
88
1.23
0.19
2.1
1.3
—
—
—
0
0
29
255
1.12
0.19
2.1
2.7
56.05
54.04
%
0.37
29
255
6
50
1.18
0.19
1.7
2.5
5.95
3.72
mg/l
—
6
50
6
51
1.16
0.19
1.0
1.1
—
—
—
0
0
44
398
1.09
0.18
2.6
2.0
222.16
171.64
u/ml
0.47
25
186
7
57
1.21
0.18
1.0
1.1
—
—
—
0
0
5
69
0.71
0.16
1.4
1.8
4.52
6.54
ug/l
—
5
63
8
67
1.17
0.16
1.1
1.3
90.63
116.09
pmol/l
—
8
67
120
1225
0.95
0.16
4.4
4.4
1.80
1.97
ug/l
0.21
108
1113
208
1985
1.04
0.16
1.9
2.0
—
—
—
0
0
32
287
1.10
0.16
1.1
1.3
—
—
—
0
0
31
278
1.10
0.15
2.0
1.3
—
—
—
0
0
65
674
0.94
0.15
1.6
1.5
—
—
—
0
0
14
158
0.87
0.15
1.2
1.3
0.69
22.41
u/ml
—
9
129
32
288
1.09
0.15
1.1
1.3
—
—
—
0
0
60
623
0.94
0.15
1.4
1.3
—
—
—
0
0
7
88
0.78
0.14
1.7
1.5
—
—
—
0
0
16
138
1.14
0.14
5.5
3.5
1.67
2.51
mmol/l
1.71
16
130
8
96
0.82
0.13
1.0
1.0
—
—
—
0
0
41
376
1.07
0.13
4.0
4.6
12.32
19.10
ug/l
0.18
30
294
26
276
0.92
0.11
1.8
1.6
—
—
—
0
0
514
5000
1.02
0.10
6.0
5.3
36.90
37.87
mmol/mol
2.01
490
4766
209
2089
0.98
0.10
4.4
4.3
6.98
8.28
mmol/l
3.72
193
1870
5
43
1.14
0.10
1.0
1.0
10.85
14.63
u/ml
—
5
33
18
192
0.92
0.08
1.6
1.8
172.94
216.52
pmol/l
0.99
18
182
34
351
0.95
0.08
1.9
1.6
0.28
0.27
mg/l
0.08
15
154
24
251
0.94
0.07
4.3
2.5
30.97
34.92
u/ml
0.15
24
240
12
106
1.11
0.07
2.3
3.3
21.64
19.50
mmol/l
0.19
12
101
8
77
1.02
0.07
1.1
1.1
—
—
—
0
0
50
473
1.04
0.06
2.1
2.0
6.10
6.24
ph
0.48
31
306
114
1141
0.98
0.06
2.3
2.0
—
—
—
0
0
31
318
0.95
0.05
1.1
1.3
336.08
236.60
miu/ml
0.93
12
161
77
739
1.02
0.05
1.3
1.4
—
—
—
0
0
91
877
1.02
0.04
2.6
2.5
2.41
2.44
mmol/l
1.36
76
767
63
604
1.03
0.04
1.5
1.4
—
—
—
0
0
28
264
1.04
0.04
1.5
1.8
39.04
39.23
nmol/l
0.02
28
257
141
1399
0.99
0.03
4.6
4.4
10.12
8.70
mg/mmol
0.13
97
950
24
245
0.96
0.03
1.1
1.1
0.84
0.89
g/l
0.53
24
245
11
116
0.93
0.03
1.2
1.3
97.09
102.85
pmol/l
0.04
11
110
57
550
1.02
0.02
2.7
2.1
15.83
13.38
iu/l
0.36
47
375
11
101
1.07
0.02
1.6
1.4
12.86
11.80
u/ml
—
6
87
31
297
1.02
0.01
1.7
1.7
1.13
5.08
iu/ml
—
7
55
16
151
1.04
0.00
1.3
1.4
—
—
—
0
0
24
239
0.98
0.00
1.1
1.1
1.40
1.49
g/l
1.40
24
239
142
1390
1.00
0.00
3.9
3.8
52.43
79.59
mg/l
0.58
99
972
27
263
1.01
0.00
3.1
2.8
1.02
1.02
ratio
0.10
21
237
13
124
1.03
0.00
2.1
1.4
26456.00
11822.29
e6/l
—
8
95
48
475
0.99
0.00
2.8
1.6
—
—
—
0
0
13
132
0.97
0.00
2.4
2.6
—
—
—
0
0
16
162
0.97
0.00
1.6
1.6
0.16
0.33
nmol/l
2.21
11
128
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
6097.00
—
0
9
0
5
0.00
-0.00
0.0
3.0
—
189.80
—
0
5
7
74
0.93
-0.00
8.1
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.03
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.97
-0.00
1.7
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.6
—
0.50
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.96
-0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
132.67
—
0
6
0
5
0.00
-0.00
0.0
3.4
—
0.22
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.93
-0.00
1.6
7.4
—
47.10
—
0
10
5
58
0.84
-0.00
1.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_CONGEN_MALFO_GREAT_ARTERIES and mortality.

Females

Parameter HR [95% CI] p-value
Q17_CONGEN_MALFO_GREAT_ARTERIES 3.101 [2.4, 4.0] < 0.001
Birth year 0.997 [0.99, 1.01] 0.421

During the follow-up period (1.1.1998 — 31.12.2019), 246 out of 5292 females with Q17_CONGEN_MALFO_GREAT_ARTERIES died.

Males

Parameter HR [95% CI] p-value
Q17_CONGEN_MALFO_GREAT_ARTERIES 2.705 [2.21, 3.31] < 0.001
Birth year 0.985 [0.98, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 5278 males with Q17_CONGEN_MALFO_GREAT_ARTERIES died.

Mortality risk

Mortality risk for people of age

years, who have Q17_CONGEN_MALFO_GREAT_ARTERIES.

N-year risk Females Males
1 0.375% 0.496%
5 1.882% 2.813%
10 4.585% 7.174%
15 8.942% 13.541%
20 15.7% 22.229%

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_GREAT_ARTERIES – Congenital malformations of great arteries

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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